Abstract: A medical system suitable for delivering a fluid to a patient according to multiple modes of operation, including a safety mode that additionally enables the delivery or the treatment to continue even when a probable anomaly is detected.

Abstract: The invention relates to a system of performing an evidence Dialysis modality of Batch, Tidal or a combination of both. The system: isolates cavity volume changes due only to ultrafiltrate; determines the volume of a patient cavity; determines a full cavity; determines an objective time to initiate an exchange; and determines an empty cavity. One or more combination of these features provide for evidence base Fill, Dwell, and Drain sequences. The system comprises: a cassette having a heated region and a sensor region for measurements. A valve manifold supplies a patient connection with fluid. A microprocessor receives pressure measurements, controls the heated region and activates a volumetric pump to deliver or extract discrete increments of the fluid to the cassette from bags. Filtering pressure measurements to remove rapid fluctuations determines an accumulated pressure in the patient cavity. The volume of fluid in the patient cavity correlates to the accumulated pressure.

Abstract: A wearable ultrafiltration apparatus is provided. The apparatus can include a first dialyzer for filtering a patient's blood along a first fluid path and a second dialyzer for filtering the patient's blood along a second fluid path. The apparatus can also include a valve being positionable in a first position for directing the patient's blood along the first fluid path. The valve can also be positioned in a second position for directing the patient's blood along the second fluid path. When the valve is in the first position, blood can flow along the first fluid path and prevent blood from flowing along the second fluid path. When the valve is in the second position, blood can flow along the second fluid path and prevent blood from flowing along the first fluid path. When the valve is in the first position, the second dialyzer can be idle and capable of being serviced or replaced and when the valve is in the second position, the first dialyzer can be idle and capable of being serviced or replaced.

Abstract: A blood isolation and extraction method includes: providing a predetermined amount of blood; utilizing a platelet filter unit to filter the predetermined amount of blood to generate a filtered blood; utilizing a plasma separation unit to divide the filtered blood into a plasma layer and a blood cell layer for separating blood cells from blood plasma; and extracting the blood plasma from the plasma layer and the blood cells from the blood cell layer. In another embodiment, the blood isolation and extraction method further includes: providing a platelet-washing unit to wash the platelet filter unit with a solution to produce a platelet solution; and mixing the platelet solution with the blood plasma to produce a platelet and plasma mixed solution.

Abstract: A drain cassette for a dialysis unit has a fluid channel between venous and arterial connection ports, and a valve may controllably open and close fluid communication between a drain outlet port and the venous connection port or the arterial connection port. A blood circuit assembly and drain cassette may be removable from the dialysis unit, e.g., by hand and without the use of tools. A blood circuit assembly may include a single, unitary member that defines portions of a pair of blood pumps, control valves, channels to accurately position flexible tubing for an occluder, an air trap support, and/or other portions of the assembly. A blood circuit assembly engagement device may assist with retaining a blood circuit assembly on the dialysis unit, and/or with removal of the assembly. An actuator may operate a retainer element and an ejector element that interact with the assembly.

Abstract: The present invention relates to an apparatus for monitoring a vascular access device, including at least one signal generator for generating vibrations in order to stimulate the vascular access device or a portion thereof to vibrate, at least one signal receiver for detecting vibrations of the vascular access device or of said portion thereof, and at least one evaluation device for evaluating the detected vibrations. Moreover a method for monitoring the vascular access device by using the apparatus of the invention is specified.

Abstract: A system for controlled delivery of medical fluids to a patient includes an inlet conduit attached to a source of a medical fluid and an outlet conduit connected to the patient. The inlet and outlet conduits are interconnected by a multiple stage control valve assembly and a pair of syringes. The control valve assembly is alternated between a first state wherein the inlet conduit communicates with a first syringe for transmitting fluid from the source to the first syringe, a second state wherein the first syringe communicates with a second syringe and is isolated from the inlet conduit and the outlet for transmitting fluid from the first syringe to the second syringe, and a third state wherein the second syringe communicates with the outlet and is isolated from the inlet and the first syringe for transmitting fluid from the second syringe to the patient through the outlet.

Abstract: An IV line identification system to enable ready identification of an IV line and its associated fluid source and output from other IV lines with their fluid sources and outputs. The IV line identification system includes an optical member fixed to elongated member that emits light when a light source provides a light into the optical member.

Abstract: The disclosure relates to a drug delivery device having a drive unit includes a stator comprising a plurality of coils consecutively arranged in an axial direction, and an armature axially movable within the stator, the armature including a number of magnets and pole shoes consecutively arranged in the axial direction. A respective pole shoe is arranged between respectively neighbouring magnets. At least one axial end of the armature comprises a terminal pole shoe.

Abstract: An inserter for inserting a needle or cannula of an infusion set comprises a fixed inserter member and a movable inserter member movably connected to said fixed inserter member and adapted to receive the infusion set. The movable inserter member is movable from a first position to a second position to expose the needle or cannula. The movable inserter member is locked to the fixed inserter member in the first position to prevent accidentally exposing the needle or cannula.

Abstract: Disclosed herein are devices, methods and systems for monitoring and detection of adverse events in a subject. In an embodiment, an insulin delivery device includes an insulin injection device in communication with a controller for controlling the insulin injection device. The controller is configured to receive a heart signal from one or more heart sensors, and a blood glucose signal from one or more blood glucose sensors. The controller is further configured to analyze changes in the heart rhythm of the subject based on the heart signal and determine, based on the changes in the heart rhythm and the blood glucose signal, whether the subject is and/or will be experiencing an adverse event. Upon determination that the subject is or will be experiencing an adverse event, the controller determines one or more parameters of delivery of insulin to be delivered to the subject.

Abstract: The present invention relates to a signal delaying assembly for a medicament delivery device, said assembly comprising a delay female member containing a fluid, a delay male member having at least one passage, a delay unit connected to the delay female member or to the delay male member, wherein a relative movement between the male member and the female member and towards each other causes the transfer of said fluid from said female member through the at least one passage for slowing said movement, characterized in that the delay unit is releasably connected to a signal generating assembly for delaying at least one feedback signal.

Abstract: A drug delivery device includes a container for storing a drug, the container having a stopper for expelling the drug; an injection drive comprising an energy source for directly or indirectly acting on the stopper to expel the drug; a sensor for detecting contact between the drug delivery device and a body of a patient; and a user interface (UI) for activating or causing the activation of the injection drive. The device is operative for drawing attention to the UI, if the sensor detects contact between the drug delivery device and the body of the patient, to thereby indicate that the injection drive is ready to be activated, which activation is the next step in the drug administration process.

Abstract: The present utility model provides an electrically powered needle-free injector (100), comprising: a needle-free injector body (120); and a needle-free injection end (130) extending distally from the needle-free injector body (120) for medicine administration, the needle-free injector body (120) comprises: a housing (3), an inside of which is divided into a pressurized injection chamber (123) and a motor chamber (124); a pressurized injection assembly (170) disposed within the pressurized injection chamber (123); a needle-free injector locking mechanism (180) at least partially disposed within the pressurized injection chamber; and a motor assembly (190) disposed within the motor chamber (124). The present utility model has a beneficial effect that it may provide a power source for the needle-free injector to electrically take medicine and inject by a built-in motor; it works reliably, is used conveniently, and has a small size.

Abstract: A medical syringe which is suitable for dispensing and injecting medical foams is described and claimed. The syringe has a standard syringe plunger and barrel arrangement but comprises a flexible annular flange on the inner surface of the barrel. The annular flange extends inwards and forwardly from a base portion, affixed to the inner surface of the barrel to contact the plunger shaft and form a seal. The shape and orientation of the annular flange enables injection of medical foam with reduced sputtering of the syringe contents which make administration of sclerosing foams more controllable.

Abstract: An optical decoding system including an optical sensor integral with or attachable to a housing of a drug delivery device and configured to be directed at first and second rotatable components of a dose setting and dispensing mechanism of the drug delivery device and a processor configured to: (i) cause the optical sensor to capture images of the first and second rotatable components at least at the beginning and end of a medicament dose dispensing process; (ii) determine a rotational position of both the first and second rotatable components in each of the captured images; and (iii) determine from the rotational positions of the first and second rotatable components an amount of medicament delivered by the dose setting and dispensing mechanism of the drug delivery device.

Abstract: A stopper/piston (510) having a cylindrical body (511) having a front axial end closed by a front wall (513). The hollow cylindrical body (511) includes an outside surface provided with a secondary sealing profile (610), the front wall (513) including a front axial outside surface (631) provided with a coating (635). The front wall (513) includes a primary sealing profile (630) on its radially-outer edge, the front wall (513) and the cylindrical body (511) is made of different materials, the hollow cylindrical body (511) being overmolded on the front wall (513). The front axial outside surface (631) of the front wall (513) includes a deformation profile (633) arranged radially inside the primary sealing profile (630), the deformation profile adapted to deform radially for insertion of the stopper/piston (510) into a syringe body.

Abstract: The present invention relates to a monitoring device for monitoring operation of a drug delivery device and to a respective drug delivery device, wherein the monitoring device comprises: a fastening member (32) to releasably attach the monitoring device to an axially elongated housing (14) of the drug delivery device (10), a sliding member (40) shiftable relative to the fastening member (32) in an axial direction (1, 2) and being adapted to operably engage with at least one dose setting component (17, 18, 26) of the drug delivery device (10) to follow an axial displacement of the dose setting component (17, 18, 26) relative to the housing component (14), a first sensor arrangement (36, 46) for detecting a rotation of the dose setting component (17, 18, 26) relative to the fastening member (32), a second sensor arrangement (38, 48) for detecting an axial displacement of the sliding member (40) relative to the fastening member (32), and a processing member (34) coupled to the first and to the second sensor a

Abstract: A medication injecting apparatus has a cartridge housing and a drive housing that is threadedly connected to the cartridge housing for axial displacement relative to one another. The drive housing has a helical-shaped passage and a flexible drive member is slidingly disposed within the helical-shaped passage and extends axially outwardly therefrom toward the cartridge housing. The flexible drive member is movable in the axial direction relative to the drive housing during dose setting and is axially fixed relative to the drive housing during injecting. A clutch has an engaged position and a disengaged position. The flexible drive member is axially fixed relative to the drive housing when the clutch is in the engaged position and the flexible drive member is movable relative to the drive housing when the clutch is in the disengaged position.

Abstract: A modular retractable needle assembly having a unitary propellant release structure is provided. The modular retractable needle assembly can be coupled to a suitable syringe. A modular filler needle can be provided that is engageable to the syringe. Kits comprising the modular retractable needle assembly, one or more syringes, and a modular filler needle are provided.

Abstract: A multi-beveled needle point geometry for hypodermic needles such as pen needles. A proximal bevel is formed at a first angle of inclination, a pair of intermediate bevels at a second angle of inclination, and a pair of distal bevels at a third angle of inclination and differing angles of rotation. The second angle of inclination is substantially different than the first angle of inclination to define a marked apex at the intersections between the proximal bevel and the intermediate bevels. At least one smooth transition is typically provided between adjacent bevels, between a bevel and an outer surface of the needle, and/or between a bevel and the lumen of the needle.

Abstract: A medicinal-liquid administering device is for administering medicinal liquid filling a tubular body into a living body under a pressing action of a plunger. The medicinal-liquid administering device includes: a disposable part including: the tubular body, the plunger, and a movable part configured to be moved from an initial position and to press the plunger toward a distal-end side; a reusable part that is attachable to and detachable from the disposable part, the reusable part including: at least part of a driving part configured to move the movable part, a first position detection sensor configured to detect whether or not the movable part is at the initial position in a state before the movable part is moved, and an alarm part configured to output a first alarm when the first position detection sensor detects that the movable part is not at the initial position.

Abstract: An ultrasonic nebulizer includes a working tank configured to be detachable with respect to a main body. The working tank includes a rod-shaped tank-side contact electrode that extends in a vertical direction along an outer wall of the working tank. A specific portion that corresponds to a portion in a circumferential direction of the outer circumferential surface of the tank-side contact electrode is exposed from the outer wall, and the remaining portion of the outer circumferential surface of the tank-side contact electrode is embedded inside of the outer wall and is connected to an electrode of an ultrasonic vibrator. A main body-side contact electrode comes into contact with the specific portion of the outer circumferential surface of the tank-side contact electrode when the working tank is mounted on the main body.

Abstract: An ultrasonic nebulizer includes: a working tank in which an ultrasonic vibrator is incorporated and in which a working liquid is stored facing the ultrasonic vibrator; a medicine tank that stores a medicinal liquid, at least a bottom portion thereof being dipped in the working liquid; and a main body that includes an oscillation circuit that is to drive the ultrasonic vibrator. The medicine tank is configured to be detachable with respect to the working tank. The working tank is configured to be detachable with respect to the main body.

Abstract: A method of treatment for mixed carbon dioxide, carbonic acid, saline and optional active additives for treating lower body cavity ailments includes delivery of dosage of the treatment at specified flow rates, using a) main housing having a hollow central area containing the dosage; b) a dosage dispenser head located at the distal end of the main housing, and having at least one flow channel for movement of the dosage from the main housing through the dosage dispenser head and to external of the dosage dispenser head; c) a dosage release control component located between the main housing and the dosage dispenser head to permit flow of the dosage through the dosage dispenser head in response to increased pressure against the dosage; and d) a pressure-changing moveable component on the main housing.

Abstract: Systems and methods are provided for aerosolizing and delivering therapeutic substances in an electronic aerosol delivery device with airflow regulation. Calibrated airflow resistance settings enable adjustment and control of flow velocity and or flow volume of air, aerosolized air, and or entrained aerosol particles, through the device, for optimal aerosol delivery among diverse conditions and applications.

Abstract: A container for holding, dispensing and/or storing a preferably liquid medicament preparation is proposed, which comprises an inner space for the medicament preparation and an at least partially multi-layered wall structure defining the inner space, the wall structure comprising a first layer with a first through-opening of less than 40 ?m. Alternatively or additionally, the wall structure comprises a second and third layer, a second through-opening being provided in the second layer and the third layer covering or closing off the wall structure.

Abstract: An inhaler for dispensing a pharmaceutical to infants and respiratory compromised patients is disclosed.

Abstract: Systems and methods are disclosed for delivering medication to a patient. One such system has an aerosol generator for aerosolizing medication. The generator is located outside the airway of a patient. A chamber is provided for receiving aerosolized medication from the generator. The system has a carrier gas supply tube for delivering carrier gas to the chamber, and an aerosol delivery tube for receiving the aerosolized medication and the carrier gas from the chamber. The aerosol delivery tube delivers the aerosolized medication to the patient. A distal end of the aerosol delivery tube is positioned inside the airway of the patient in order to discharge the aerosolized medication within the patient's airway.

Abstract: The present invention relates to a method for protecting a ventilation device of a ventilator against backflowing exhaled air, and to a ventilator. A respiratory gas flow is generated by a blower device and is guided via a flow connection to a breathing interface. The respiratory gas flow is adjusted with the aid of a control device to a first ventilation pressure during an inhalation phase of the patient and to a second ventilation pressure during an exhalation phase. A characteristic variable for a flow within the flow connection is detected in this case by means of a monitoring device for monitoring backflowing exhaled air. And, in this case, a back pressure with respect to the backflowing expiratory flow is adjusted by means of a specific increase of the ventilation pressure with consideration for the characteristic variable, whereby an undesirable rebreathing into the ventilation device is counteracted by means of the back pressure.

Abstract: A breathing assistance apparatus includes an inner volumetric member pressurizable from a first pressure to a second pressure and an outer volumetric member surrounding at least a portion of the inner expandable volumetric member. The inner volumetric member pressurizes the outer volumetric member as the inner volumetric member is pressurized from the first pressure to the second pressure. In another embodiment, a breathing assistance apparatus includes exhalation and inhalation chambers with respective biasing members providing for the exhalation chamber to apply a pressure to the inhalation chamber and thereby provide assisted inhalation. Methods for assisting breathing are also provided.

Abstract: The present invention relates to a method for operating a data processing unit of a ventilation device, and also to a ventilation device. Therapy data are registered and stored in a memory unit and at least a part of the therapy data is transmitted with a transmission unit to a network. At least one available radio network is determined with the transmission unit and at least one parameter for a network quality of the network is defined. At least one processing of the therapy data prior to their transmission into the radio network is carried out dynamically with the data processing unit depending on the parameter.

Abstract: The invention relates to a method of controlling a respiratory assistance apparatus delivering a flow of gas, particularly a flow of air, comprising the steps of measuring at least one parameter indicative of said flow of gas; converting said at least one parameter indicative of said flow of gas into at least one signal indicative of said flow of gas; processing said at least one signal indicative of the flow of gas in order therefrom to deduce at least one item of information relating to cardiac massage being performed on a patient in cardiac arrest; on the basis of said at least one deduced item of information, automatically selecting a given ventilation mode from among a number of stored ventilation modes, and controlling the respiratory assistance apparatus by applying the selected ventilation mode. Respiratory assistance apparatus capable of implementing said control method.

Abstract: The invention relates to a respiratory-aid apparatus (1) capable of supplying a stream of gas to a patient (P), comprising a gas-transport pipe (2) for transporting a stream of gas, such as air; measurement means (6) designed to measure at least one parameter representing the stream of gas and to supply at least one signal corresponding to said at least one parameter representing said stream of gas, for example the gas flow rate or pressure; signal-processing means (8) designed to process said at least one signal from the measurement means (6) and to deduce therefrom at least one piece of information (I1, I2, I3) characterising a cardiac massage performed on a patient; and display means (7) designed to display said at least one piece of information (I1, I2, I3) characterising a cardiac massage from the signal-processing means (8).

Abstract: The invention relates to an aerosol delivery device (10) comprising an aerosol generator (3) for generating an aerosol in the aerosol delivery device (10), a sensor (5) configured to detect a use of the aerosol delivery device (10) for aerosol treatment, and a controller (7) configured to deactivate the aerosol generator (3) if no use of the aerosol delivery device (10) for aerosol treatment is detected by the sensor (5). Further, the invention relates to a method for operating an aerosol delivery device (10), comprising the steps of operating an aerosol generator (3) for generating an aerosol in the aerosol delivery device (10), detecting a use of the aerosol delivery device (10) for aerosol treatment by means of a sensor (5), and deactivating the aerosol generator (3) by means of a controller (7) if no use of the aerosol delivery device (10) for aerosol treatment is detected by the sensor (5).

Abstract: The present invention relates generally to medical devices, methods, and kits. More particularly, the present invention relates to improved endotracheal tubes or patient ventilation tubes which prevent the leakage of proximal secretions to the distal airways.

Abstract: A tracheostomy tube (1) has a movable and lockable flange (2) by which the tube can be supported about the neck of a patient. The flange has a rotatable locking ring (34), which is threaded with a housing (26) fixed with the wings (22 and 23) of the flange. A resilient sleeve (50) is located in a recess (44) of the locking ring between a compression surface (45) on the locking ring at one end and the floor (46) of the housing at the opposite end. When the locking ring (34) is twisted it is moved forwardly along the housing (26), thereby compressing the resilient sleeve (50) axially. The axial compression causes the sleeve (50) to expand radially against the outside of the tube (1) and the inside of the housing (26), thereby locking the flange (2) in position.

Abstract: An interface pillow for insertion into a nostril of a user for delivering positive air pressure (e.g. during sleep) has a pliable member having a body. The body has an insertion end and a distal sealing end that includes a seal for interfacing with a cannula. An insertion bulge extends from the body limiting an insertion distance into the user's nostrils. An insertion area of the body extends between the insertion end and the insertion bulge, the sides of which angle inwardly towards the insertion end at an angle. The outer shape of the insertion area is flattened on one side for interfacing with a septum of a nose, and an upper interface area of the outer shape of the insertion area is narrower than a lower interface area of the outer shape of the insertion area to conform to a shape of a nostril of the nose.

Abstract: A wearable device (8,60,70,86) structured to exert a contact pressure between the wearable device and a skin surface of a wearer, such as a patient interface device for delivering a flow of breathing gas to a patient, includes a first member (18,72,96), such as a faceplate member, structured to have a first pressure applied thereto, a contact member (14,74), such as a sealing cushion, structured to exert the contact pressure against the skin surface in response to the first pressure, and a support member (20,62,78) positioned between the first member and the contact member, the support member including a plurality of compression members (40,52,54,64,84), wherein each of the compression members is structured to buckle in response to a compression force having at least a first predetermined level being applied to the support member.

Abstract: An oxygen face mask composed of a molded vinyl/polyvinyl/rubber or silicone mask with a medical grade mineral oil gel strip on the bridge of the nose extending over the contour of the cheeks on both side of the patient's face, an extended under-the-chin portion of mask and decreased length dimension of an existing standard face mask to deliver oxygen and aerosolized medications to the user. Use of this face mask during aerosolized medication of medical gas or oxygen delivery allows for a better seal against the face, greater comfort to the user, more stability and good securement of the mask, and a mask size that decreases irritation of the user's eyes caused by leakage at the nose and cheek portions of a standard oxygen mask. The oxygen mask configuration can applied to both pediatric and adult patients.

Abstract: A cushion tension assembly for a respiratory interface device is provided. Cushion tension assembly includes an adjustment assembly and a number of tension members. Each tension member is operatively coupled to the adjustment assembly and is operatively coupled to the cushion body. In this configuration, the adjustment assembly is structured to move cushion body between a first configuration in which the cushion body provides a generally continuous seal, and a second configuration in which the cushion body provides a more complete seal.

Abstract: An interface device comprises a cushion and a shell coupled thereto which together define an interior space with the face of a user. The shell includes an inlet port structured to have a conduit carrying a flow of treatment gas to the interior space selectively coupled thereto and a first aperture structured to allow the passage of ambient air into the interior space. A first sealing member is operatively coupled to the shell and is positioned such that the first sealing member is movable between a first state in which the first sealing member substantially seals the first aperture, and a second state wherein the sealing member does not substantially seal the first aperture. The first sealing member moves between the first state and the second state responsive to breathing of the patient.

Abstract: A mask assembly suitable for the treatment of sleep disordered breathing, comprising: a mask to provide pressurized air to a patient; upper and lower slot features located on each side of the mask; a headgear assembly, comprising: a back portion; a pair of upper straps provided to the back portion, each upper strap having a loop portion and a hook portion at a free end thereof for releasably attaching to the loop portion; a pair of lower straps extending away from the back portion, each lower strap having a loop portion and a hook portion at a free end thereof for releasably attaching to the loop portion; and a connection region of each loop portion of each strap, the connection region being adapted to receive a respective hook portion, the connection region being wider than each respective hook portion along each respective hook portion's entire length.

Abstract: A respiratory assembly is provided. The assembly includes a base engaged with at least one connector and in fluid communication with a hose or fluid source for allowing the gaseous flowthrough between the at least one connector, the base and the hose or fluid source. The assembly further includes a pair of sockets engaged with the at least one connector, and a pair of posts, each post selectively engageable with at least one of the pair of sockets. Each post includes a flange that defines an opening therethrough, the openings in fluid communication with each corresponding socket of the pair of sockets. Each post further includes an adhesive adhered to each flange and configured for sealably engaging a patient's nare.

Abstract: A tube cleaning apparatus for cleaning a CPAP hose or other hose including a trough for receiving a tube therein, the trough curving downwardly from an apex to an engagement mechanism associated with each opposite end portion of the trough for hanging the hose therefrom, the opposite end portion of the hose being engageable with the engagement mechanism for allowing the hose to soak with a cleaning solution therein, and the hose being receivable within the trough with its opposite end portions extending downwardly from the apex for drying purposes.

Abstract: An anesthesia device configured to measure the hydrogen concentration in an anesthesia gas containing a hydrogen gas includes: an anesthesia gas preparation circuit configured to generate anesthesia gas by mixing an air or an oxygen mixture air with a vaporized anesthetic; a closed circuit-type or semi-closed circuit-type respiratory circuit including a gas circulation passage configured to circulate the hydrogen-containing anesthesia gas containing the hydrogen gas and the vaporized anesthetic; and a hydrogen concentration measurement circuit configured to measure the hydrogen concentration in the hydrogen-containing anesthesia gas in the gas circulation passage, wherein the hydrogen concentration measurement circuit includes: an anesthetic removing member having a removability of the vaporized anesthetic in the hydrogen-containing anesthesia gas; and a hydrogen concentration measuring instrument provided on the secondary side of the anesthetic removing member.

Abstract: A capnography system (100, 400), comprising: a controller (110, 410) configured to obtain a sample gas flow from a physical interface (107) for a patient (101); determine a change in a characteristic of the sample gas flow during a sampling time interval; determine whether the change in the characteristic of the sample gas flow during the sampling time interval is equal to or greater than a corresponding threshold value; determine that supplemental oxygen is provided when it is determined that the change in the characteristic of the sample gas flow is equal to or greater than the threshold value; and determine that supplemental oxygen is not provided when it is determined that the change in the characteristic of the sample gas flow is less than the threshold value.

Abstract: A nebulizer tubing comprising an inlet configured to be connected to a gas source and an outlet configured to be connected to a nebulizer. The nebulizer tubing comprises a port configured to be covered during inhalation to allow airflow from the gas source to the nebulizer and uncovered during exhalation to stop the airflow from the gas source to the nebulizer by allowing gas to escape from the nebulizer tubing. The airflow activates a nebulization process.

Abstract: Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure.

Abstract: Methods and apparatuses for improving sleep by transdermal electrical stimulation (TES). In general, described herein are methods for applying TES to a subject, and particularly the subject's head (e.g., temple/forehead region) and/or neck with an TES waveform adapted to improve sleep, including reducing sleep onset (falling to sleep) more quickly and/or lengthening the duration of sleep. TES waveform(s) particularly well suited to enhancing sleep are also described herein.