Abstract: A braking system for a rollator with a frame includes an adjustable handle to be installed on a right subframe or a left subframe of the frame of the rollator, a bracket fixedly connected to the handle, a lever rotatably connected to the bracket, a lock movably connected to the bracket and configured to fix the lever in a locked position when the lock is moved relative to the bracket once the lever is rotated toward the frame, and a wire operably connected between the lever and a brake on the frame of the rollator, such that the wire applies the brake when the lever is rotated toward the bracket and when the lever is fixed in the locked position.

Abstract: A rolling walker comprises a frame, a seat supported by that frame, and a backrest supported by the frame. By one approach the backrest is configured to selectively move between a first position that provides back support for a person sitting in the seat facing in a forward direction and a second position that provides back support for a person sitting in the seat facing in a rearward direction. If desired, this backrest can be comprised of a material (such as a memory foam material) that biases the backrest towards that first position when the backrest is in the first position and that biases the backrest towards the second position when the backrest is in the second position.

Abstract: A method for guiding the blind is disclosed. The method includes: determining a target direction; and controlling a mechanical device to shift its center of gravity toward the target direction according to the target direction; wherein the mechanical device comprises a balance weight, a connecting rod, and a rotating axis, the connecting rod is connected to the rotating axis, and the balance weight is located on the connecting rod.

Abstract: An orthosis for a vacuum treatment of the deformations of the thorax includes a bottom, a peripheral lip made of flexible, elastically deformable material and comes into sealing contact with the thorax so as to form a treatment space using negative pressure, and at least one suction head connected to a negative pressure generation component. The orthosis improves the sealing contact between the orthosis lip and the patient's thorax by increasing the orthosis deformability. To achieve this, the lip has a constant elasticity along the entire periphery thereof, and the bottom is formed of hollow, rigid, transverse side-by-side compartments connected to each other by bridges made of the same flexible material as the peripheral lip of the orthosis. The bridges of material allow the bottom to deform in such a way that the orthosis shape adapts to the thorax anatomy when the orthosis is applied vertically to the thorax.

Abstract: A system and method for promoting angiogenesis and adipogenesis in soft tissue using a tissue enlargement apparatus. The tissue enlargement apparatus includes an interface configured for affixation to the soft tissue. A force generating device is coupled to the interface by a connecting tube for applying mechanical forces to the soft tissue. A processor is coupled to the force generating device and is configured to apply intermittent cyclical patterns of the mechanical forces to the soft tissue to promote angiogenesis and adipogenesis in soft tissue. The intermittent cyclical patterns are based on at least one of duration, frequency, and intensity of the mechanical forces.

Abstract: An inflatable belt 100 for use in a BFR system with an outer belt material 102 hermetically sealed to an inner belt material 101 along a perimeter, thereby forming at least one inflatable chamber 103, the inflatable chamber having an input port 104 for accepting a gas into the chamber, the inflatable belt further comprising a first fastening means 110 in communication with the outer belt material, for attaching to a second fastening means 111 in communication with the outer belt material, thereby locking a circumference of the inflatable belt, when wrapped around a user's limb, efficacy feedback means 200 for gathering efficacy feedback data 205, for use in prescribing, monitoring and adjusting one or more training parameters of a BFR training session and/or program based on evaluation of the efficacy feedback data.

Abstract: An adjustable fitness and massage roller formed as a tubular structure is disclosed. The tubular structure has protrusions that can be continuously adjusted via an adjustment mechanism to extend out from the circumferential surface of the roller. In a basic position the circumferential surface is smooth and the he protrusions are not extending outward. In an extreme working position the protrusions are in utmost extended position. The user can adjust the surface of the roller according to her/his preference by adjusting the position of the protrusions.

Abstract: Provided is a decompression device that varies a stimulus and tightening force to a penis by adjusting pressure in a container.

Abstract: A medical, or fertility aid, or sensual device including: an outer cylindrical phallic shaped outer cover; a cylindrical phallic shaped liquid filled enclosed casing pocket; rechargeable vibrating/infrared/ultrasound core inserted into the outer cover, wherein the liquid filled pocket contains a ferrous metal disk which can be bent; and a sheath encasing the outer cover. One embodiment relates to a vibrating, and or infrared, and/or ultrasound, and heat emitting and self-hardening dildo fertility devise which offers a solution for women with endometrial or uterine caused infertility. It can also be used as an aid in re-habilitation for women recovering from trauma to the vagina due to radiation therapy in the treatment of cervical and uterine cancers.

Abstract: Methods are disclosed for treating a subject having a disease or disorder comprising providing the subject with an acoustic energy stimulus derived from a disease-specific, condition-specific, endogenous mediator-specific or pharmacologic agent-specific neurogram in an amount and manner effective to treat the disease or disorder.

Abstract: This invention is directed toward a method of neutralizing a past hurtful or anxiety-provoking memory using the practitioner's hands in a variety of steps to apply pressure and movement to the hand and wrist of a patient or upon the practitioner himself or herself, utilizing the method.

Abstract: A method to increase the overall hemodynamic efficacy of cardiopulmonary resuscitation (CPR) by alternating between chest compression-decompression cycles optimized to either cardiac output or venous return. The phases of cardiac output and venous return enhancement may themselves by adjusted in their duration and character. The method may enhance mechanical and manual techniques delivered to the anterior or circumferential chest, and be synchronized to adjunctive techniques such as airway, ventilatory or abdominal therapies.

Abstract: Devices, systems and methods for stimulating (e.g., noninvasively) a subject's inflammatory reflex are provided to reduce bleed time. The method may include the step of non-invasively stimulating the inflammatory reflex (e.g., the vagus nerve, the splenic nerve, the hepatic nerve, the facial nerve, and the trigeminal nerve) of a subject, such as by mechanical stimulation, in a manner which significantly reduces bleed time in the subject. Devices for non-invasively stimulating the inflammatory reflex may include a movable tip or actuator that is controlled to mechanically stimulate the ear. The devices may be hand-held or wearable, and may stimulate the cymba conchae region of the subject's ear.

Abstract: A bag assembly (100) capable of withstanding sterilization by gamma irradiation. The bag (100) includes two walls, each wall composed of at least one sheet (176, 178) of a fluoropolymer film, and a fitment (200). The first and second walls are attached to the fitment (200) along one edge (148) of the bag assembly (100) and sealed to each other along a perimeter (142, 144, 146, 147, 149) of the bag assembly (100).

Abstract: A blood collection device including a flow path to flow blood by capillary action capable of collecting a large amount of blood is provided. The blood collection device includes an introduction inlet 23 for introducing the blood of the subject M, a substrate 20 connected to the introduction inlet 23 and including a flow path 25 to flow the blood by capillary action, and a cooling body 30 for cooling the flow path 25.

Abstract: A system is provided for storage and reconstitution of IV solutions. The system may include one or more storage and reconstitution devices each configured to store and manipulate IV solution containers containing IV solutions in crystalline form that include hydration chemicals and therapeutic drugs. Crystalline hydration chemicals may include crystalline salts and sugars. The containers may be dimensionally precise enough for mechanical manipulation and configured such that sharp objects such as needles are not needed for fluid delivery to or from the container. Each storage and reconstitution device may store stacked containers and may include components for retrieval of a container from the storage and for reconstitution of the contents therein using a sterile water source within the device. IV doses may be manufactured, under appropriate standards, that can be mechanically reconstituted to produce high-quality doses in real time on the patient care unit or in the pharmacy.

Abstract: Devices for delivery of fluid compositions include a delivery device including an internally pierced blister in which the device includes a plunger configured to crush the blister and deliver the contents in a lateral direction with respect to the motion of a dispensing button. Certain devices are configured for oral delivery.

Abstract: A bite-safe artificial nipple is constructed of polymeric materials sufficiently soft and elastic to replicate a nursing mother's nipple tissue. Added to the soft, elastic matrix phase is a braided fibrous mesh tube to prevent a small bitten-off portion of the nipple from becoming separated from the rest of the teat, thereby preventing a choking hazard. The braided fibrous mesh tube is arranged in a very specific configuration, so that it experiences neither tension nor compression as the teat is compressed or elongated in use and so does not act to “reinforce” the soft, elastic matrix phase which would otherwise create a classic load-transfer composite destroying the soft, elastic properties of the matrix phase needed for the desired functioning of the artificial teat.

Abstract: The disclosure discloses an anti-flatulence milk bottle, which comprises a bottle body and a nipple, wherein an edge of the nipple is arranged at a bottleneck of the bottle body through a threaded cover, the threaded cover is in threaded connection with a periphery of the bottleneck, a first air returning cover and a second air returning cover are arranged between the nipple and the bottleneck, a first gap is formed between the first air returning cover and the second air returning cover, a second gap is formed between the threaded cover and an outer surface of the bottleneck, the first gap is communicated with the second gap, the first air returning cover is provided with a first opening communicated with an interior of the bottle body, and the first gap, the second gap and the first opening form a confluence passage.

Abstract: As a result of the repeated incidents (described in the Background section), the inventor decided to create a layer of soft cushioned strap that would allow the pacifier gently stay in a baby's mouth until the person holding (in charge of caring) or the baby decides to remove it. This creates a sanitary method of continuous satisfaction for the baby, which in turn reduces baby's crying—wanting a support, substitute nourishment, or a method to keep the baby busy, rested and unstressed. The invention may be in four (4) design types, using the same material but creating a variable styles (i.e. PH, PHB, PHC and PHD) as shown in Specification section.

Abstract: Metal-containing methacrylates incorporated into polymeric materials with antimicrobial capacity for biomedical applications, and more particularly for dental purposes, are provided. The incorporation of metal-containing methacrylates such as calcium methacrylate, tin methacrylate, copper methacrylate, silver methacrylate, in combination or alone, for potentializing antimicrobial effect of cements, in particular, to biomaterial compositions including metal containing methacrylates, such as calcium, tin, copper, silver, nickel, titanium and iron methacrylates, in the formulation of biomaterials for applications in human health provides advantages, particularly in dentistry, and allows for expressive antimicrobial activity to dental compositions, so as to be useful in dental prosthesis, operative dentistry, orthodontics, pediatric dentistry, implantodontics, and endodontics.

Abstract: The present invention relates to a microcomplex containing a modified nanoparticle adsorbed on a host microparticle and to a process to obtain it. The microcomplex is particularly useful for photoepilation. The present invention also relates to a composition containing the microcomplex and to the method for enhanced photoepilation based on the microcomplexes.

Abstract: Compositions and methods for administering collagen to a human subject have been developed. The collagen-containing lipid vesicles of the invention provide a delivery system for human collagen which eliminates problems associated with chemical and physical instability of the collagen as well as immune responses to non-human collagen.

Abstract: An oral care mouth rinse composition containing at least one ionic tin source and polyvinylpyrrolidone wherein the polyvinylpyrrolidone is present in an amount of from 1.5 to 4 weight % based on the total weight of the oral care mouth rinse composition is provided.

Abstract: The present invention describes a cosmetic or dermatological composition for use in the antibacterial and/or anti-inflammatory treatment comprising a combination of vegetal extracts titrated in salicin and 1,2-alkanediols, preferably 1,2-decanediol and willow bark (Salix alba) extract.

Abstract: A lead or chalk or color tablet for writing, drawing and/or cosmetics purposes, contains at least one sugar and/or sugar alcohol and/or pentaerythritol, at least one cellulose derivative and/or starch derivative and at least one surfactant. The at least one surfactant is selected from the group of sulfuric acid fatty acid ester salts and/or fatty acid sulfoalkyl esters and/or ethoxylated forms of alkali metal fatty acid sulfates. A pencil having such a lead and to a method for producing a lead or chalk or color tablet are also provided.

Abstract: A cosmetic method of reducing perspiration comprising the topical application of a composition comprising a non-pore blocking antiperspirant agent of general formula (I): Ar—CHaCHa—X wherein Ar is an aryl group, a is 1 or 2, and X is a sub-structure of formula CH(OH)—Y or CO.Z, wherein Y is a C1-C10 hydroxyalkyl group and Z is a C1-C10 hydroxyalkyl group or a C1-C10 oxyalkyl group.

Abstract: A skin cleansing composition comprising a salt of lauric acid; a salt of stearic acid; and at least one surfactant that is not a salt of a fatty acid; wherein the ratio of the salt of lauric acid to the salt of stearic acid, calculated as the ratio of lauric acid to stearic acid by weight, is from 2.5:1 to 3.5:1. Also provided are methods of using the compositions.

Abstract: A cleansing composition is provided for removing waxy makeup, and for cleansing the skin with excellent rinse speed and after-feel. The inventive composition is also transparent and stable to phase separation and includes specific amounts of high average HLB nonionic surfactants, specific alkyl mono esters, hydrocarbon oils and polyol(s) and in a preferred embodiment contains very low levels of or no silicone oils.

Abstract: This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, and a fluoride source, as well as to methods of using and of making these compositions.

Abstract: The invention provides for methods for treating a hiar loss disorder in a subject by administering a Janus Kinase/Signal Transducers and Activators of Transcription inhibitor.

Abstract: A shampoo composition including (a) a silicone polymer including (i) one or more quaternary groups; (ii) at least one silicone block comprising greater than 200 siloxane units; (iii) at least one polyalkylene oxide structural unit; and (iv) at least one terminal ester group, and (b) a detersive surfactant. The silicone polymer has a viscosity of up to 100,000 mPa·s. The silicone polymer is a pre-emulsified dispersion with a particle size of less than about 1 micron.

Abstract: Certain configurations of adhesive materials are described which comprise a crosslinked derivatized atelocollagen that can be cured with a sequestered curing agent. In some configurations, the crosslinked, derivatized atelocollagen is used to provide an adhesive that can be used to hold two or more tissues to each other for some period and permit a tissue repair process to occur.

Abstract: A colloidal dispersion is disclosed comprising poly alpha-1,3-glucan or poly alpha-1,3-1,6-glucan and a solvent. The colloidal dispersion has utility in various applications, including food, oil field, pharmaceutical, personal care and specialty industries.

Abstract: A method for dyeing hair includes applying a polyvinyl amine copolymer solution to the hair; and applying a hair dye composition to the hair. A hair dye composition includes an aqueous base fluid; a polyvinyl amine copolymer; and an anionic or cationic hair dye. A method of making a hair dye composition includes mixing a polyvinyl amine copolymer and an anionic or cationic hair dye into an aqueous base fluid.

Abstract: The present invention relates to a particularly effective protective coating for metallic objects, the coating method, and the special applications thereof. The particularly high protective effect is achieved by the adaptation of the inorganic fraction and the organic polymer fraction of the coating to the specific surface of the object. Further adjustments of the coating can be used for further optimization, for example of the protection properties or other product properties.

Abstract: This invention is a hydrogel capsule with a fragrance encapsulated therein during the polymerization process. The hydrogel capsule is of use in fabric care or personal care formulations.

Abstract: A dental bleaching composition comprises a dental bleaching agent and a polyvinylpyrrolidone thickening agent. The bleaching composition may include a liquid component, flavoring agents, a basic substance and desensitizing agents, as desired. Polyvinylpyrrolidone avoids acid etching and chelation of teeth that were problematic in bleaches using carbomer as a thickener. A delivery system for delivering the bleaching composition comprises the aforementioned dental bleaching composition in combination with a moisture-resistant barrier layer such as a dental tray or a flexible strip of material.

Abstract: Cosmetic agents for simultaneously lightening and temporarily shaping keratin fibers include a specific thickener and also at least one oxidant and have a viscosity of from 31,000 to 90,000 mPas. Despite the high viscosity, the agents can be easily removed from the packaging and moreover can be homogeneously applied to the keratin fibers without said agents dripping after application. The agents result in a homogeneous lightening and a good hairstyle hold. A method for lightening and temporarily shaping keratin fibers uses such cosmetic agents.

Abstract: Described herein are oral care compositions comprising a crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, together with particular co-polymers as additional excipients; including some embodiments which further comprise a calcium abrasive.

Abstract: The present invention relates to an aerosol device comprising a container containing: —one or more propellants, —a hair composition comprising: (i) one or more polymers containing a silicone unit bearing alkoxy-(aminomethyl)-silyl functional groups; (ii) one or more amphoteric fixing polymers and/or one or more cationic fixing polymers; the propellant(s) possibly being present in the composition or, in the container, separate from the composition.

Abstract: The present invention relates to a process for treating the hair, which comprises: a) the application to the hair of a composition comprising one or more polymers containing a silicone unit bearing alkoxy-(aminomethyl)-silyl functional groups, b) the application to the hair of steam by means of a device that is capable of generating steam, step b) possibly preceding, following or being simultaneous with step a).

Abstract: The present invention relates to compositions and methods for the prevention and treatment of skin disorders and for the rejuvenation of the skin. In particular, the application describes topical compositions and methods of treatments comprising the combined use of one or more cannabinoids and one or more hydroxy acids in a suitable carrier.

Abstract: The present invention relates to the use, in a cosmetic composition, of a peppermint extract, as agent intended to increase renewal of the cells of the epidermis associated with a deficiency in the expression of NOTCH proteins in keratinocyte progenitor cells, in particular for mature skin and/or skin exhibiting signs of dryness and of loss of firmness. The invention also relates to a cosmetic care method, for maintaining or regulating renewal of the cells of the epidermis associated with a deficiency in the expression of NOTCH proteins in keratinocyte progenitor cells, intended for mature and/or dry skin.

Abstract: Described are microorganisms which are able to inhibit the formation of foot malodor by skin microorganisms. Also described are compositions comprising such microorganisms as well as the use of such microorganisms in cosmetic, prophylactic or therapeutic applications.

Abstract: A transdermally absorbable base material including: a lipid peptide compound including at least one of compound of Formula (1) below and the similar compounds or pharmaceutically usable salts thereof; a surfactant; a specific polyhydric alcohol; a fatty acid; and water, wherein R1 is a C9-23 aliphatic group; R2 is a hydrogen atom or a C1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; R3 is a —(CH2)n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms, or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.

Abstract: Pharmaceutical formulations and methods useful for the treatment of anorexia and the stimulation of appetite and weight gain, and the management of weight loss in dogs and cats.

Abstract: The present disclosure relates to injectable compositions sterile injectable fluid compositions comprising a polysaccharide having a color in the visible spectrum, methods of forming the same, kits containing the same, and methods for performing agent-assisted procedures in a patient using the same.

Abstract: The invention provides methods and compositions for reducing tumor-mediated immune evasion and inducing patient-specific immunization.

Abstract: Compositions useful for improving effectiveness of alpha-2-adrenergic agonist components include carrier components, alpha-2-adrenergic agonist components, solubility enhancing components which aid in solubilizing the alpha-2-adrenergic agonist components. In one embodiment, the alpha-2-adrenergic agonist components include alpha-2-adrenergic agonists. In another embodiment, the solubility enhancing components include carboxymethylcellulose.