Abstract: Sterilization device, in particular for sterilization of packaging material, comprising a first chamber, a barrier element and a connection area. The first chamber is adapted to provide charge carriers for sterilization, and the connection area is connected to a third chamber so that the barrier element forms at least one part of the boundary of a volume in which a first atmosphere exists.

Abstract: Ultraviolet radiation is directed within an area. The target wavelength ranges and/or target intensity ranges of the ultraviolet radiation sources can correspond to at least one of a plurality of selectable operating configurations including a sterilization operating configuration and a preservation operating configuration.

Abstract: A decontamination operation chamber is partitioned into a first operation chamber and a second operation chamber. A connecting portion that connects the first operation chamber and the second operation chamber can be closed. The pressure of the first operation chamber and the second operation chamber is adjusted by a pressure-adjusting mechanism. When the connecting portion is opened and the first operation chamber and the second operation chamber are connected, an inlet portion for the first operation chamber and an outlet portion for the second operation chamber are closed and air flow is generated from the second operation chamber to the first operation chamber by the pressure-adjusting mechanism. When carrying an object into an aseptic manipulation chamber, the object is housed in the first operation chamber and a first decontamination operation is performed, then the object is transferred to the second operation chamber and a second decontamination operation is performed.

Abstract: The deodorizing mask of the present invention has a main body part that includes a deodorizing fiber layer containing a composite fiber having a chemical adsorption type deodorizer bonded to the surface of a fiber with an adhesive composition. The chemical adsorption type deodorizer is a component having at least one type selected from copper and zinc elements. The adhesive composition includes at least one type selected from polyester, poly vinyl alcohol, cellulose, starch, poly acrylamide, poly alkylene oxide and poly vinyl pyrrolidone.

Abstract: The invention relates to methods for air disinfection of microorganisms and biological agents by the method of their inactivation by electrostatic fields and filtering by the method of electrostatic precipitation. The method comprises the steps of creating a flow (A) of air to be disinfected; subjecting said flow to constant with electrostatic fields alternating in direction of intensity vector, said electrostatic fields being sequentially arranged along the flow, and created by transversely spaced air permeable electrodes (1); and filtering the treated flow with an electrostatic filter. Electrostatic field concentrators in the form of projections (3) are located on the surface of the electrodes (1), in particular nanoscale projections, and the intensity of each of the alternating electrostatic fields between the electrodes is selected in accordance with the condition of electroporation of microorganism cells or their inactivation. A device for implementing this method is also claimed.

Abstract: A thin nanocomposite film for use in an absorbent article (e.g., sanitary napkin) is provided. The film contains a first ethylene polymer having a density of about 0.94 g/cm3 or less, second ethylene polymer having a density of greater than 0.94 g/cm3, and nanoclay having an organic surface treatment. The present inventors have discovered that through selective control over the particular type and concentration of the components used to form the film, as well as the manner in which it is formed, the properties of the film can be significantly improved.

Abstract: One aspect of the present invention generally relates to methods of sealing a wound or tissue plane or filling a void splace. In a preferred embodiment, the wound is an ophthalmic, pleural or dural wound. In certain instances, the compositions used to seal the wound or tissue plane comprises a polyalkyleneimine. In a preferred embodiment, the polyalkyleneimine is polyethyleneimine. Treatment of the polyethyleneimine with a cross-linking reagent causes the polyethyleneimine polymers to polymerize forming a seal. In certain instances, the cross-linking reagent is a polyethylene glycol having reactive terminal groups. In certain instances, the reactive terminal groups are activated esters, such as N-hydroxy succinimide ester. In certain instances, the reactive terminal groups are isocyanates. In certain instances, the polyethyleneimine has a lysine, cysteine, isocysteine or other nucleophilic group attached to the periphery of the polymer.

Abstract: The invention relates to medicine and specifically to combustiology, to surgery, and to cosmetology and can be used as a bioplastic material for replacing defects in epithelial tissues (protecting against evaporation and infection) and for stimulating regeneration. The technical result is increased efficacy in healing wounds. The goal is achieved in that a histo-equivalent bioplastic material is used which includes a substrate in the form of a matrix, the material for which is a native form of hyaluronic acid, distinguished in that the histo-equivalent bioplastic material contains a 1.5% solution of hyaluronic acid and a 5% solution of a peptide complex which are mixed until a viscous elastic gel is formed, situated in the foundation and subjected to ultraviolet photopolymerization in a biosafety cabinet over the course of 5-7 hours at the following quantitative ratio in ml: 1.

Abstract: A bioprosthetic tissue having a reduced propensity to calcify in vivo, the bioprosthetic tissue. The bioprosthetic tissue comprises an aldehyde cross-linked and stressed bioprosthetic tissue comprising exposed calcium, phosphate or immunogenic binding sites that have been reacted with a calcification mitigant. The bioprosthetic tissue has a reduced propensity to calcify in vivo as compared to aldehyde cross-linked bioprosthetic tissue that has not been stressed and reacted with the calcification mitigant.

Abstract: A femoral head support device, in particular a mineralized collagen-based femoral head support device applicable to the treatment of early osteonecrosis of femoral head. The device is made from a dense, homogeneous organic/inorganic composite, wherein the organic phase includes collagen and inorganic phase includes nano calcium phosphate salt, and the device is of a cylinder having an upright through hole and also has a support strength of up to 4000-6000N. By implementing a method for manufacturing such mineralized collagen-based femoral head support device, the mineralized collagen-based femoral head support device with mechanical properties equivalent to human cortical bone can be manufactured; and the mineralized collagen-based femoral head support device can meet the demand for clinical treatment of early osteonecrosis of femoral head to avoid the continuous collapse of necrotic femoral head.

Abstract: Provided is a malleable implant configured to fit at or near a bone defect site to promote bone growth, the malleable implant comprising: a biodegradable polymer, mineral particles, and an oxysterol, the implant configured to become moldable upon being wetted with a fluid. Methods of making and use are further provided.

Abstract: The present disclosure provides an engineered collagen composition comprising collagen, wherein the collagen composition is compressed to form a gradient of at least one physical property. Methods of using and of manufacturing the engineered collagen compositions of the present disclosure are also provided.

Abstract: A bioabsorbable medical device or a medical device component comprises an absorbable component prepared by subjecting a prefabricated component of an iron-based raw material to ion nitriding. Substance composition inside the absorbable component changes with the depth from the surface. The absorbable component comprises at least a first part and a second part. The first part surrounds the second part. Hardness of the first part is higher than hardness of the second part. An interface exists between the first part and the second part. A crack generated in the first part is impeded by the interface when extending to the second part. On the premise of ensuring radial stand strength, the bioabsorbable medical device or medical device component and a preparation method thereof reduce wall thickness of an iron-based stand, improve a stand corrosion rate and malleability, and achieve broader adaptability.

Abstract: The invention involves bioresorbable stents which elute nitric oxide (NO). The stent is comprised of three main key design elements: a bioresorbable scaffold, a bioresorbable polymeric coating layer(s), and NO-releasing nanoparticles incorporated in the bioresorbable polymeric coating layer, and optionally also in the scaffold. The NO-releasing nanoparticles are made of nontoxic biocompatible and biodegradable materials; for example a chitosan polymer and optionally a sugar.

Abstract: A method and apparatus are disclosed for determining status of a canister of a topical negative pressure (TNP) system. The method includes the steps of monitoring pressure provided by a pump element of the TNP system, determining at least one characteristic associated with the monitored pressure and determining status of at least one parameter associated with a canister of the TNP system responsive to the determined characteristics.

Abstract: A surgical hand piece is described that maintains a vacuum pressure within the hand piece at a selected level. A check valve is provided substantially near an inlet of an integrated aspirating pump. The check valve opens to introduce fluid into the hand piece to maintain the vacuum pressure within the hand piece at or above the selected level so as to prevent or substantially reduce post-occlusion flow.

Abstract: The invention relates to an aspiration catheter for the extraction of thrombotic maternal from blood vessels. The catheter has a first and a second lumen, the first lumen being distally provided with an aspiration opening and the second lumen having a smaller cross section than the first lumen and extending coaxially in the distal region of the first lumen. The second lumen is provided with a lateral as well as a distally located opening, the lateral opening reaching through the wall of the catheter. Within the first lumen a stabilization wire is movably arranged which terminates distally of the lateral opening of the second lumen but proximally of the aspiration opening of the first lumen.

Abstract: Systems and methods for a reduced-pressure interface for providing reduced pressure through a sealing member to a distribution manifold includes a housing having a flange portion and a cavity wall portion such that the cavity wall portion forms a cavity having a tissue-facing cavity opening. A conduit port is coupled to the cavity wall and has a conduit aperture, such that the conduit port is adapted to receive a reduced-pressure delivery conduit. An attachment device is coupled to a tissue-facing side of the flange portion of the housing such that the attachment device couples the housing to the sealing member. Additionally, a cutting element is at least temporarily coupled to the housing proximate to the tissue-facing cavity opening such that the cutting element is adapted to form an aperture in the sealing member when the cutting element is driven into the sealing member with a driving force.

Abstract: Embodiments of a breast pump shield are disclosed herein. According to various embodiments, the breast pump shield can include a body portion that has a breast engagement portion and a neck portion. The breast engagement portion can include a ring. The breast engagement portion can receive at least a portion of a breast of a user, and the neck portion can be configured to receive at least a portion of a nipple of the user and to receive milk from the breast. The breast pump shield also can include a suction chamber located in proximity to the neck portion, and a cover located at the ring of the body portion. The cover can include a support layer and a lubricant layer. The cover can provide at least part of a hermetic seal for the breast pump shield prior to use.

Abstract: The catheter device comprises a motor located at the proximal end of the catheter device and a drive shaft, extending from the proximal end section to the distal end section of the catheter device, for driving a rotating element located at the distal end of the catheter device. The catheter device also comprises a hose-like catheter body which encompasses the drive shaft and extends from the proximal end section to the distal end section of the catheter device. At the proximal end of the catheter device, the drive shaft is connected to a motor by a clutch. The clutch is a magnetic clutch with a proximal and a distal magnet unit. The proximal magnet unit is connected to the motor and the distal magnet unit to the drive shaft. The distal magnet unit is mounted fluid-tight in a clutch housing. The proximal end of the catheter body makes a fluid-tight connection with the clutch housing.

Abstract: Apparatus, systems, and methods are provided for optimizing intracardiac filling pressures and cardiac output in patients with heart failure, conduction disease, and atrial fibrillation. The system is able to adjust and optimize intracardiac filling pressures and cardiac output by adjusting heart rate and the effective amount of total body blood volume. The device includes an adjustable member that may create a mean pressure differential in order to manifest an effective “mechanical diuresis” by sequestering extraneous blood volume to the high-capacitance of the venous vasculature. The system is therefore designed to reduce intracardiac filling pressures while maintaining or even increasing cardiac output.

Abstract: An assembly includes at least two medical treatment units, each of which can be allocated to a patient and at least two peripheral devices, each of which can be allocated to a patient. The peripheral devices and the treatment units have means for allocating a peripheral device to a treatment unit and means for verifying the allocation of a peripheral device to a patient. To allocate a peripheral device to a treatment unit, the peripheral device is placed by operators in a receiving unit belonging to the treatment unit. Said receiving unit is preferably designed as a charging station for the battery of the peripheral device. In the event of a successful allocation of peripheral device and patient, confirmed by the receipt of physiological data of the patient, the operators verify the correct allocation of a peripheral device to the patient and must confirm the correct allocation by confirmation means.

Abstract: The invention relates to a method and apparatus for optimizing an extracorporeal blood treatment using an extracorporeal blood treatment apparatus, an extracorporeal blood treatment apparatus with a device for optimizing the extracorporeal blood treatment, and a computer program to be executed on a processor for carrying out a method for optimizing the extracorporeal blood treatment. The method and apparatus are characterized in that at least one machine-specific treatment parameter for carrying out the treatment using the respective dialyzer or filter is determined with a computing unit for different types of dialyzers or filters. The computing unit determines the costs resulting from the determined machine-specific treatment parameters when using the respective dialyzer or filter. The determined costs for different types of dialyzers or filters are then displayed on a display unit. The doctor can then select the dialyzer or filter to keep the costs as low as possible.

Abstract: A blood purification apparatus which can perform actions and operations according to the final stage of blood-return.

Abstract: Device for removing substances from blood and other fluids such as water, wastewater, chemicals and other biofluids, includes i) an electrocatalytic decomposition filter including a DC power source, a set of electrodes with a catalytic surface or in direct contact with sorbents offering catalytic activity, ii) an electrosorption filter including a DC power source, a set of electrodes, nanostructured sorption material and/or a porous polymer matrix, iii) an inlet for entry of blood or blood plasma or dialysate fluid into the device, iv) an outlet for the removal of purified blood, blood plasma, ultrafiltrate or dialysate fluid from the device, and v) a conduit connecting the inlet with the outlet and holding the electrosorption filter such that the blood, blood plasma, ultrafiltrate or dialysate fluid is forced through the electrosorption and electrocatalytic decomposition filter, and vi) a sensor and control system to safeguard the device from producing oxidative stress.

Abstract: The invention relates to a method for reducing the number of leukocytes in blood through treating the blood in an arrangement of a plurality of fibers based on organic polymers, whereby the blood is channeled along the fibers and whereby the reduction in leukocytes from the blood occurs essentially through adsorption on the fibers, characterized in that the plurality of fibers based on organic polymers is fixed in a housing with an inlet arrangement and an outlet arrangement, and that the blood is channeled via the inlet arrangement into the housing, flows through the housing with the plurality of fibers made from organic polymers, and exits the housing via the outlet arrangement, that the arrangement of the fibers shows a high degree of order, that the blood flows along the external surface of the fibers, and that the fibers cause a generation of the complement activation product C5a in a concentration of at least 10 ?g per m2 of fiber surface.

Abstract: To monitor an extracorporeal blood circuit during extracorporeal blood treatment, the arterial pressure and venous pressure in the arterial branch and venous branch of the extracorporeal circuit are measured by pressure sensors, and the sum Ps and the difference ?P of the arterial pressure and/or venous pressure measured at the same time are calculated. A possible error state is indicated when the sum Ps and/or difference ?P lie outside predetermined limit value windows A and B. To reduce the susceptibility to error, a check is preferably also made to ascertain whether the two above conditions are satisfied for n successive measurements.

Abstract: The invention relates to a pump-inflow-cannula (1) providing a blood conduit from a heart (2) and/or from an associated vessel to an external blood handling system. The pump-inflow-cannula comprises a body (3), encompassing an essentially axially extending inflow-lumen (4), having a distal-end (5) for an attachment of the inflow-lumen (4) to the blood handling system, and having a proximal-end (6) for an introduction of blood from the heart (2) and/or from the associated vessel into the inflow-lumen (4), wherein at least one projection (7) is provided at the proximal-end (6) to deflect a heart muscle from intruding into the inflow-lumen (4), wherein the body (3) of the pump-inflow-cannula comprises a reinforcement-means (8). The invention is also related to a pump-outflow-cannula (19) and to a blood managing system comprising a pump-inflow-cannula and a pump-outflow-cannula in accordance with the present invention.

Abstract: The invention provides a medical intravenous support apparatus that facilitates patient mobility while reducing the likelihood of an accidental fall. The design incorporates improved features for bag support, tube management, cord management, patient steadiness, user-friendly braking, and electric power supply.

Abstract: An apparatus and method are disclosed for controlling infusion of liquid into a patient using a peristaltic pump. The liquid infusion apparatus includes a liquid conduit having a proximal segment, a distal segment and an intermediate segment. The liquid infusion apparatus also includes a flow valve in fluid communication with the intermediate and distal segments. The flow valve includes a shuttle member slidably disposed within a housing about the distal segment, the shuttle member being configured for lateral movement relative to an elongated axis of the distal segment. The shuttle member is configured to operate in a first configuration to impede fluid flow through the liquid conduit and in a second configuration for which fluid flow through the liquid conduit is unimpeded. The shuttle member includes a resilient grasper for selectively engaging and disengaging a mating actuator resiliently received by the grasper.

Abstract: A micropump that pumps liquid using electrothermally-induced flow is described, along with a corresponding self-regulating pump and infusion pump. The micropump has applications in microfluidic systems, such as biochips. The self-regulating infusion pump is useful for administration of large and small volumes of liquids such as drugs to patients and can be designed for a wide range of flow rates by combining multiple micropumps in one infusion pump system. The micropump uses electrode sequences on opposing surfaces of a flow chamber that are staggered with respect to each other. The opposing surfaces include staggered electrodes that have the same phase and same electrode sequence. As such electrodes with the same phase are staggered and not eclipsed.

Abstract: A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

Abstract: There is provided a cassette unit that is suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The cassette unit housing cavity is arranged for receipt of a syringe that is suitable for use in the injected delivery of drug to a patient. The cassette unit includes a removable cap that in a capping position fits over and thereby, acts such as to close off, the needle projection aperture. The cassette unit includes a cap lock feature movable from a first cap locking position in which it prevents removal of the removable cap from the capping position with the cassette unit to a second cap non-locking position in which it no longer prevents such cap removal.

Abstract: A miniature portable multifunctional infusion device includes a liquid bottle (4) and a film box body (16) secured to a support frame (1). The film box body (16) is respectively provided with a directional input interface (17) and a directional output interface (14) in communication with the liquid bottle (4) and a needle via an infusion pipe. The film box body (16) is installed with an elastic film (27), and a transmission system (31) is arranged at a side of the elastic film (27). The transmission system (31) includes a miniature direct current motor (32) connected to a frequency modulating system (28). The miniature direct current motor (32) is connected to a spiral straightening device (34) via a speed reducer (33), and the spiral straightening device (34) is connected to a reciprocating film propping device (36) via a two-order shaft (43). A truncated cone (39) of the reciprocating film propping device (36) at a front end is in contact with the elastic film (27).

Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.

Abstract: A fluid infusion device includes a pump having a rotor and a stator. A rotor cam element rises from a reference surface of the rotor. The stator includes a cam element having a stator cam surface. The cam elements axially displace the rotor as the rotor revolves. Inlet and outlet valves open and close as a function of angular and axial position of the rotor. A motor actuates the rotor to pump fluid to a body, via a subcutaneous conduit. First and second contact elements are located on the rotor. A sensing element on the stator cooperates with a detection circuit to detect when the sensing element makes contact with the first sensor contact element and the second sensor contact element. The detection circuit monitors a detection signal obtained from the sensing element to determine an operating condition of the fluid pump mechanism.

Abstract: A controller for an insulin infusion device includes at least one processor device and at least one memory element that cooperate to provide a processor-implemented closed-loop start-up module. The start-up module is operated to initiate a closed-loop mode of the infusion device and to obtain a most recent sensor glucose value for the user. The start-up module also calculates a difference between the most recent sensor glucose value and a target glucose setpoint value. When the difference is less than or equal to a threshold value, the closed-loop insulin infusion rate is adjusted over time, based on a fixed final target glucose value that is derived from the target glucose setpoint value. When the difference is greater than the threshold, the infusion rate is adjusted over time, based on a dynamic final target glucose value that decreases over time toward the target glucose setpoint value.

Abstract: Some embodiments an infusion pump system can be configured to control dispensation of medicine according to a closed-loop delivery mode that is responsive to feedback information provided from a monitoring device, and the infusion pump system permits a user to interrupt the closed-loop delivery mode for purposes of dispensing a user-selected manual bolus dosage.

Abstract: The vial holder is a device that is used to support a vial or injectable bottle in a partially inverted position so as to enable a hypodermic needle of a syringe to be inserted without fear of an unintended prick to an end user. The vial holder is further defined with a weighted base that is adapted to lie on a support surface. The weighted base includes a vertical member that rises vertically. A pair of holding armatures extend upwardly and away from the vertical member. The pair of holding armatures radiate away from one another and form “V”. The pair of holding armatures is adapted to support the injectable bottle at a partially inverted position.

Abstract: The invention relates to an arrangement for detecting a position of a plunger relative to a bung in a drug cartridge, comprising a proximity sensor located close to a distal end of the plunger facing the bung and aligned to receive light reflected by the bung.

Abstract: A medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module (4) containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle (3). The medicated module (4) does not require the user to manually engage a reservoir (22) containing the secondary medicament. Instead, a biasing member (48) automatically activates the reservoir (22) when the needle guard (42) is retracted. The needle guard (42) prevents accidental needle sticks before and after an injection, and locks after dose delivery.

Abstract: A package including a vessel made of cyclic olefin polymer (COP) resin, a CVD coating on a vessel, and a medicament comprising at least one protein, peptide, and/or DNA sequence is disclosed. Methods for processing a vessel, for example to provide lubricity or hydrophobicity, are also disclosed. The interior surface of the seated vessel can be processed via the vessel port by PECVD. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed.

Abstract: Exemplary embodiments provide automatic injection devices, housing components for automatic injection devices and methods for fabricating the same. An exemplary housing of an automatic injection device may be overmolded with one or more gripping surfaces to facilitate gripping and manipulation of the automatic injection device by a user when performing an injection. In an exemplary embodiment, an overmolded left gripping surface may extend along a left side of the housing and an overmolded right gripping surface may extend along a right side of the housing opposite to the left side.

Abstract: The present invention relates to a delivery device for delivering predetermined amounts of fluid, comprising a body (10), a container (16) filled with fluid to be delivered arranged inside said body, said container comprising an opening for expelling said fluid and a wall (18) movable inside said container (16), a threaded plunger rod (46) arranged movable inside said body (10) in the longitudinal direction and in contact with said movable wall (18), a manually operated push means (14, 60) movable in the longitudinal direction capable of, upon operation, move said plunger rod (46) towards said movable wall (18), thereby expelling fluid, and means for transforming a generally linear movement of said push means (14, 60) to a rotational movement of said plunger rod (46).

Abstract: Provided is a metered quantity syringe-type dispenser that is capable of multistage pushing. The metered quantity syringe-type dispenser includes a syringe; a plunger configured to be pushed into the syringe; an elastic deforming portion configured to be deformed in response to the pushing of the plunger; and a stopper portion configured to be locked with respect to the syringe and to be released from the locking by restoring force of the elastic deforming portion.

Abstract: The invention provides a dispense interface for an ejection device comprising a first part and a second part, at least a first opening, a second opening and a third opening, a fluidic channel and a connection element for each of the openings, wherein the first part is joined to said second part to form at least a part of said fluidic channel connecting said openings with each other and wherein each connection element is configured to accept a needle assembly for a fluid tight connection with said corresponding opening in order to reduce the complexity and provide an easy usage of the dispense interface and at the same time overcome the problems of material compatibility and cross contamination. The invention also relates to a system comprising a dispense interface according to the invention and a needle assembly for each opening. Furthermore, the invention relates to a method for preparing a dispense interface according to the invention.

Abstract: A medical fluid supply device including at least first and second fluid containers which are arranged to be mutually displaceable, at least first and second selectably openable fluid communication pathways associated with the first and second fluid containers and at least one selector switch assembly for selectably opening the first and second selectably openable fluid communication pathways, mutual displacement of the first and second fluid containers changing the amount of fluid in at least one of the at least first and second fluid containers in accordance with a state of the at least one selector switch assembly.

Abstract: A device is presented for injection of a product into an injection site, comprising: a container provided with a needle, a housing receiving the container, and a needle shield releasably coupled with the container. The device also includes a retaining arrangement provided at or near the distal end of the device, designed for preventing the container from moving distally with respect to the housing until the needle shield is removed from the container.

Abstract: A syringe body/needle assembly is provided that is free of an organic adhesive bond. The assembly includes a syringe body having a nozzle that has an opening; a needle fixed in the syringe body or in the nozzle; and a connecting body made of doped glass. The opening through which the needle is introduced into an interior of the syringe body is hermetically sealed to the needle. The connecting body includes a first material that absorbs more electromagnetic radiation within a wavelength range than a second material from which the syringe body is made.

Abstract: The present invention relates to a medical device for intradermal or subcutaneous treatment of a patient, comprising: a piercing element to penetrate a skin portion of the patient; an illumination arrangement to illuminate the piercing element and/or to illuminate the skin portion prior and/or during a treatment process, wherein the illumination arrangement is further adapted to visually indicate a predefined treatment sequence of the treatment process.