Abstract: The present disclosure provides a radiofrequency genicular nerve denervation probe and methods of using the probe to address chronic knee pain by producing therapeutic lesions or tissue alterations. In many embodiments, the denervation probe is a steerable, multi-electrode probe that includes one or more injection ports that allow one or more fluids to be injected at the target site before, during, or after a denervation procedure. The denervation probe may also include in many embodiments one or more thermocouples configured to provide targeted temperature readings. The denervation probe has the capability to perform a customized or preset sequence of lesions to provide desirable procedural flexibility.

Abstract: An electrosurgical probe with internal cooling for use in systems and methods for lesioning in bone and other tissue is disclosed. The probe includes a distal electrical insulator, a proximal electrical insulator, a distal electrical conductor defining a distal electrode with a closed distal end and a proximal electrical conductor defining a proximal electrode, the distal electrode longitudinally spaced apart and electrically isolated from the proximal electrode by the distal electrical insulator. The distal electrode has a closed proximal end formed by a distal face of the distal electrical insulator to thereby define a closed distal inner lumen for circulating the cooling fluid. The proximal electrode has a closed distal end formed by a proximal face of the distal electrical insulator and a closed proximal end formed by a distal face of the proximal electrical insulator to thereby define a closed proximal inner lumen for circulating the cooling fluid.

Abstract: A bipolar electrosurgical instrument includes first and second shafts each having a jaw member extending from its distal end. Each jaw member is adapted to connect to a source of electrosurgical energy such that the jaw members are capable of selectively conducting energy through tissue held therebetween. A knife channel is configured to reciprocate a cutting mechanism therealong. An actuator selectively advances the cutting mechanism. A switch is disposed on the first shaft and is configured to be depressed between a first position and at least one subsequent position upon biasing engagement with a mechanical interface disposed on the second shaft. The first position of the switch relays information to the user corresponding to a desired pressure on tissue and the at least one subsequent position is configured to activate the source of electrosurgical energy to supply electrosurgical energy to the jaw members.

Abstract: A catheter is disclosed comprising a catheter shaft including a proximal end and a distal end. A flexible framework can be connected to the distal end of the catheter shaft, wherein the flexible framework includes a plurality of heating electrodes and a temperature sensor. The plurality of heating electrodes can be configured to be heated to a first temperature, the first temperature being lower than which radio frequency ablation is performed. The plurality of heating electrodes can be configured to be heated to a second temperature, the second temperature being a temperature at which radio frequency ablation is performed.

Abstract: Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input. The system, delivery devices, and methods can damage tissue and manage scarring and stenosis.

Abstract: Devices and methods for delivering fluid to tissue during ablation therapy are described herein. An exemplary device can include an elongate body having an inner lumen, outlet ports, and an ablation element configured to heat tissue. A flow resistance of the elongate body can increase along a length of the elongate body containing the outlet ports in a proximal to distal direction. This can be accomplished by, for example, varying outlet port size or relative spacing, decreasing a cross-sectional area of the inner lumen through which fluid can flow using a flow diverter or tapered inner lumen sidewalls, or limiting a ratio between a total area of the outlet ports and a cross-sectional area of the inner lumen. Adjusting flow resistance of the elongate body can provide more uniform fluid distribution or a desired non-uniform distribution.

Abstract: This invention provides a device for mapping and ablating the renal nerves distributed on renal artery, having a guide catheter, a mapping-ablation catheter, a handle and a connector. The guide catheter has at least one lumen and a distal end with adjustable curvature. The mapping-ablation catheter is housed in one of the lumens of the guide catheter and its distal end has one or more electrodes and one or more detecting devices. The distal end of the mapping-ablation catheter is curved, rotatable, and can be extended out of or retracted into the guide catheter. The handle connects the guide catheter and mapping-ablation catheter, and has one or more controlling components for controlling the movement of the guide catheter and mapping-ablation catheter. The connector is designed to supply energy to the electrodes.

Abstract: An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a Maze procedure. The location of the ports and valves is based on using the convective cooling effect of the blood flow. The mapping can be performed by a catheter-deployed expandable net or a scanning catheter. The same net or catheter can also perform the ablation procedure.

Abstract: The present disclosure provides ablation catheter systems and electrode assemblies, including electrode baskets, for use in the ablation catheter systems for ablating tissue. The electrode baskets include a plurality of struts having a plurality of electrodes asymmetrically arranged on the plurality of struts such that upon simultaneous energizing of the plurality of electrodes during any single application of the ablation procedure, lesions are created on only one half of less of the circumference of the vessel.

Abstract: Medical devices and methods for making and using the same are disclosed. An example medical device may include a medical device for renal nerve ablation. The medical device may include an elongate shaft having a distal region. An expandable member may be coupled to the distal region. A plurality of electrodes may be coupled to the expandable member and a single conductive member may be coupled to each electrode. Where one of the plurality of electrodes is active, the remaining electrodes may be inactive and act as ground or return electrodes. The electrode of the plurality of electrodes that is active may change over time.

Abstract: Catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation are disclosed herein. In some embodiments, an apparatus includes a voltage pulse generator and an electrode controller. The voltage pulse generator is configured to produce a pulsed voltage waveform. The electrode controller is configured to be operably coupled to the voltage pulse generator and a medical device including a series of electrodes. The electrode controller includes a selection module and a pulse delivery module. The selection module is configured to select a subset of electrodes from the series of electrodes. The selection module is configured identify at least one electrode as an anode and at least one electrode as a cathode. The pulse delivery module is configured to deliver an output signal associated with the pulsed voltage waveform to the subset of electrodes.

Abstract: Catheter systems, tools and methods are disclosed for the selective and rapid application of DC voltage to drive irreversible electroporation, with the system controller configurable to apply voltages to an independently selected subsets of electrodes, such that voltages of one polarity are applied to a multiplicity of electrodes on a first medical device and voltages of the opposite polarity to a multiplicity of electrodes on a second medical device. The first and second medical devices can be epicardial catheters positioned such that their opposing distal tips are approximately aligned and whose segments with electrodes collectively wrap around the pulmonary veins.

Abstract: Medical systems, comprising at least one eletromagnetic radiation emitting device for medical applications, at least one mobile electronic device, and at least one attachable/detachable transmission medium, are provided. The electromagnetic radiation emitting device comprises a radiation source such as a laser source, a radiofrequency source, or a microwave source and required safety features/controls. The mobile electronic device has advanced computing capability and connectivity, and is capable of wirelessly accessing a network, such as a smart phone, a tablet personal computer, and the like. The transmission mediums are optical fibers, handpieces, fiber-optic systems, radiofrequency catheters and electrodes, microwave transmission media, having differently shaped distal tips, differently shaped support tubes, and lens assemblies with different focal distances. This makes the system versatile, as it can be easily adapted to a large number of diverse medical applications.

Abstract: In one aspect of the present disclosure, a laser fiber may include an optical fiber. The optical fiber may include a proximal portion. The optical fiber also may include a distal portion having a distal end. The optical fiber may be configured to transmit laser energy from the proximal portion to the distal portion for emission of the laser energy from the distal end. The optical fiber also may include a distal tip surrounding the distal portion to protect the distal portion. The distal tip may include a sheet glass material having a laser energy emitting surface. The laser energy emitting surface may be defined by a chemically-strengthened surface layer.

Abstract: A laser operation device has an elongated catheter, a light steering unit disposed at a front of a tip of the catheter, and a light irradiating unit configured to irradiate a laser to the front of the tip of the catheter, wherein the light steering unit is rotatable based on a rotary shaft and includes a plurality of prisms disposed in a circumferential direction of the rotary shaft, wherein the plurality of prisms are formed to have different deflection angles with respect to the same light, wherein the laser irradiated from the light irradiating unit is steered by refracting while passing through the prism, and wherein when the light steering unit rotates, the prism located at the front of the light irradiating unit is exchanged to adjust a steering angle of the laser.

Abstract: A system for ablation planning and treatment includes a delineation module (124) configured to distinguish tissue types in an image, the tissue types including at least a core tissue and a margin zone encapsulating the core tissue. A treatment planning module (140) is configured to apply weightings in a cost function to prioritize ablation coverage of the tissue types including the core tissue and the margin zone to determine ablation characteristics that achieve an ablation composite in accordance with user preferences. A graphical user interface (122) is rendered on a display to indicate the core tissue, the margin zone, the ablation composite and permit module user selection of one or more treatment methods.

Abstract: In one embodiment of the invention, a a minimally invasive surgical system is disclosed. The system configured to capture and display camera images of a surgical site on at least one display device at a surgeon console; switch out of a following mode and into a masters-as-mice (MaM) mode; overlay a graphical user interface (GUI) including an interactive graphical object onto the camera images; and render a pointer within the camera images for user interactive control. In the following mode, the input devices of the surgeon console may couple motion into surgical instruments. In the MaM mode, the input devices interact with the GUI and interactive graphical objects. The pointer is manipulated in three dimensions by input devices having at least three degrees of freedom. Interactive graphical objects are related to physical objects in the surgical site or a function thereof and are manipulatable by the input devices.

Abstract: Methods and systems for providing navigational feedback during a surgical procedure. A user interface is displayed on a display for viewing position and orientation of a surgical tool in a surgical field during the surgical procedure. The position and orientation of the surgical tool is tracked by a medical navigation system coupled to the processor. The user interface includes a virtual representation of the surgical tool superimposed on an image of the surgical field. A selected intraoperative position and orientation of the surgical tool is used to intraoperatively create and store a waypoint in memory. Feedback is provided to indicate the stored position and orientation of the waypoint.

Abstract: A mobile surgical robotic cart assembly used for minimally invasive surgery includes a vertical column supporting a robotic arm thereon and a base portion having at least three casters adapted to allow the surgical robotic assembly to move. The surgical robotic cart assembly further includes an immobilization assembly coupled to the base portion, the immobilization assembly being configured to move between an unlocked position and a locked position. The surgical robotic cart assembly is mobile when the immobilization assembly is in the unlocked position and immobile when the when the immobilization assembly is in the locked position.

Abstract: A method, including calculating locations of first sensors attached to a probe that has been inserted into a human patient, and calculating positions of second sensors attached to a sheath via which the probe is inserted. The method also includes calculating respective shapes of the probe and the sheath, to achieve a best fit to the calculated probe sensor locations and sheath sensor positions, while restricting the probe to pass through the sheath. The calculated respective shapes of the probe and the sheath are used to present an image of the sheath aligned with the probe.

Abstract: The present invention relates to a method, such as a surgical method for assisting a surgeon for placing screws in the spine using a robot attached to a passive structure. The present invention also related to a method, such as a surgical method for assisting a surgeon for removing volumes in the body of a patient using a robot attached to a passive structure and to a device to carry out said methods. The present invention further concerns a device suitable to carry out the methods according to the present invention.

Abstract: A touch screen interface of a medical or dental device coupled with a touchless interface to allow for sterile zone operator input, while still allowing for touch screen interaction for non-sterile zone operator input. In some embodiments, the touch screen interface usage is suspended while in a sterile zone mode, and resumed when the mode is switched to a non-sterile zone mode. In some embodiments, use of the touch screen interface while in a sterile zone mode of operation causes an alert message.

Abstract: A robotic surgical system includes a surgical robot and a guide tube. The surgical robot includes a robot arm and a controller. The controller is configured to establish a software-based remote center of motion of a surgical instrument attached to the robot arm based on a location of a surgical portal in a patient through which the surgical instrument is inserted. The guide tube having a trailing end supported by the robot arm of the surgical robot, a leading end inserted in the surgical portal and maintaining alignment between the robotic arm and the surgical portal during a surgical instrument exchange, and an elongated tubular body through which an elongated shaft of the surgical instrument is inserted or removed during the surgical instrument exchange.

Abstract: Telerobotic, telesurgical, and/or surgical robotic devices, systems, and methods employ surgical robotic linkages that may have more degrees of freedom than an associated surgical end effector in space. A processor can calculate a tool motion that includes pivoting of the tool about an aperture site. Linkages movable along a range of configurations for a given end effector position may be driven toward configurations which inhibit collisions. Refined robotic linkages and methods for their use are also provided.

Abstract: A termination assembly of a cabling system in a robotic surgical manipulator comprises a block including first and second cable pathways sized for receipt of a first cable. The first cable pathway includes a first retainer sized to prevent passage of a first fitting coupled to the first cable. The termination assembly also includes a first support coupled to the block and around which the first cable is routed.

Abstract: The present disclosure relates to force sensors and force sensor substrates for use with surgical devices.

Abstract: A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame. The bioprosthetic heart valve has a periphery, an inflow portion, and an outflow portion. The adaptive seal is coupled to the bioprosthetic heart valve around at least a portion of the periphery. The adaptive seal comprises an expandable material that expands after exposure to an initiating condition. The bioprosthetic heart valve and the adaptive seal is stored and contained within the package, which does not contain a liquid storage solution in contact with the bioprosthetic heart valve and the adaptive seal.

Abstract: The invention relates to a balloon catheter (1), which allows esophageal injuries to be prevented by the displacement of the esophagus of a patient during catheter ablation for cardiac arrhythmias. For this purpose, three balloons (7, 9, 11) are provided along a catheter shaft (3), which are arranged at a distance from each other and can each be alternately expanded in opposite directions.

Abstract: The present disclosure relates to an augmented reality (AR) image projection system capable of simultaneously capturing a real image and projecting an AR image, and capable of applying same to a subject requiring precise work or in an environment having spatial restrictions. The present disclosure includes a real image capture device for capturing a real image illuminated by invisible rays without interference with visible rays, and an AR image projection device for projecting an AR image, wherein the real image capture device captures a real image and the AR image projection device projects an AR image through the same optical axis. Further, the present disclosure includes a real image capture device, an AR image projection device, as well as additional imaging devices such as a fluorescent camera configured integrally along the same optical axis, and configured to avoid wavelength interference between a light source and an excitation light and the like.

Abstract: A medical implant that includes a scaffold having at least one receptacle for an X-ray marker. The scaffold includes a first metal. At least one (preferably monolithic) X-ray marker is disposed in the receptacle. The X-ray marker includes a second metal. An electrically insulating coating is upon the X-ray marker to prevent corrosion-promoting contact between the X-ray marker and the scaffold.

Abstract: A marking/drying tool applies ink to biological tissue using a single handheld device. A cylindrical body retains a felt tip movable between a retracted position within the body and an extended position outside the body for marking the tissue. A gas source has a manual valve to selectably dispensing a drying gas onto the tissue. In a preferred embodiment, an interlock prevents dispensing of drying gas when the tip is in the extended position and prevents the tip moving to the extended position when the manual valve is dispensing the drying gas.

Abstract: An ultrasonic instrument includes a tip portion, a transducer configured to convert electrical energy into vibrational energy, an acoustic transformer interconnecting the transducer and the tip portion, and a grip portion disposed at least partially about the acoustic transformer. The grip portion is coupled to the acoustic transformer via a resilient nodal coupling at a nodal region of the acoustic transformer. The resilient nodal coupling is configured to provide rotational and axial stability to the acoustic transformer.

Abstract: A dental guidance assembly that includes: (a) a rigid body comprising at least one tooth-shaped recess and a coupling structure; and (b) at least two dental bur guides that are each: structured to securely and removably couple to said coupling structure, and comprising an elongated slot having the following measurements: a length of 4 to 40 millimeters, a width of 1 to 4 millimeters, and a depth of 2 to 10 millimeters. The elongated slot extends along a portion of a circumference of a treated tooth, wherein the elongated slots of said at least two dental bur guides have complementary structures, such that, together, the elongated slots are configured to facilitate a limitation of the motion of a dental bur to: an entirety of the circumference of a treated tooth, and a depth suitable to form a shoulder on the treated tooth, for receiving a dental restoration.

Abstract: A multi-functional dental tool is provided which may be used for the dental filling of teeth after the removal of damage in the teeth. The dental tool comprises a forcep portion on one end and a burnisher tool on the other end. The burnisher tool portion comprises a flat burnisher and a ball burnisher, and a joint which connects the forcep portion and the burnisher tool portion. In an alternate embodiment, the dental tool comprises a penlight holder which can receive and secure a penlight, which provides illumination when performing the filling procedure, especially in situations in which an overhead light source is not readily available.

Abstract: A method for monitoring the patient's teeth positioning, including the following steps: a) less than three months after the start of an orthodontic treatment, producing an initial reference model of the patient's arches, and, for each tooth, defining, from initial reference model, a tooth model; b) acquiring at least one updated image of the arches, under actual acquisition conditions; c) analyzing each updated image and producing an updated map relative to a piece of discriminating information; d) optionally determining rough virtual acquisition conditions that approximate the actual acquisition conditions; e) searching each updated image for a final reference model corresponding to the teeth's position during the updated image's acquisition, and; f) for each tooth model, comparing the tooth model's positions in the initial reference model and in reference model obtained at the end of the preceding steps, in order to determine movement of the teeth between steps a) and b).

Abstract: An oral anterior guidance system including: a mandibular retention piece; a mandibular guidance component coupled to the mandibular retention piece, the mandibular guidance including a convex outer surface proximate a first end; a maxillary retention piece; and a maxillary guidance component coupled to the maxillary retention piece, the maxillary guidance component including a concave inner surface, wherein the concave inner surface and the convex outer surface are configured to interact to guide movement of a patient's mandibular dental arch when the mandibular retention piece and the maxillary retention piece contact as the patient's mandibular dental arch closes, and wherein the mandibular guidance component is positioned anteriorly to an anterior of the anterior wall of the mandibular retention piece.

Abstract: An orthodontic bracket includes a bracket body and a ligating member. The ligating member retains an archwire in an archwire slot and includes archwire control structure including projecting portions spaced apart in a mesial-distal direction with a recessed area therebetween. The recessed area and the projecting portions overlie the archwire slot. The recessed area may include a flat or a curved surface in a mesial-distal direction. The recessed area and projecting portions may define a radius of curvature that is less than the radius of curvature of the archwire seated in the slot. The archwire contacts one or both the projecting portions resulting in a larger moment arm and better rotational control of the bracket with the force applied by the archwire.

Abstract: Provided are a clear aligner traction device, clear aligners, and a manufacturing method thereof, by which an orthodontic force may be increased by hanging an elastic belt on the clear aligners in a case when teeth are excessively misaligned and thus incapable of being appropriately aligned using only the clear aligners. The clear aligner traction device may include a button that is integrally formed with a clear aligner body and includes a head having a relatively large width, a neck connected to the head and having a relatively small width, and a connector for connecting the neck to the clear aligner body, and a reinforcer bonded to the button in a shape corresponding to the button to reinforce the strength of the button, such that an elastic member is hooked over the button.

Abstract: An implant, particularly a dental implant is provided, having an anchoring region (12) for anchoring in a bone, which preferably includes a thread (14) for screwing in the bone, and a fastening region (22) for attaching a supra-construction, wherein an abutment region (16) adjoins the anchoring region (12), the abutment region (16) having a guide structure with a plurality of outwardly projecting ridges (18) provided thereon, and preferably, grooves (20) being formed between the ridges (20). The guide structure of the anchoring region (12) allows a better osseointegration and counteracts periimplant bone loss.

Abstract: An implant for dental prostheses includes an endosseous portion and a stump. The endosseous portion includes a crown margin configured to be opposed to a corresponding crown margin of the stump. At least one of the crown margins is conical or however has a different taper with respect to the opposed crown margin so that, once the stump has been coupled to the endosseous portion, the contact and interference surface between the crown margins is a reduced annular surface.

Abstract: A dental implant device configured as a single, solid, unitary structure, including a body portion, multiplicity of wedging edge portion, and an apical end portion, wherein the implant device is configured to be installed in a patient's mandibular or maxillary bone. The apical end portion is configured to be beveled on a multiplicity of sides. The apical end portion may also include a joining surface, the joining surface has a saw-like serration pattern, a generally jagged pattern, or a smooth pointed edge to aid in locking the implant device to the maxilla or mandible to achieve initial stability and mechanical retention. The apical end portion may further include a multiplicity of generally circular holes to generally aid bone growth and facilitate stronger osseointegration. The dental implant comprises a biocompatible material including zirconia or titanium alloy. A minimum of 5 mm of the apical end portion would be inserted into the bone.

Abstract: A method of fabricating a denture, comprising milling a preliminary try-in denture from denture material comprising a layer of denture base material contiguous with a layer of denture tooth material. Denture base material is removed from the block to form a first part of the, labial, buccal, gingival, and flange regions of the denture base to form a preliminary denture. A preliminary mold is created from this preliminary denture. The preliminary denture is then further modified with deformable waxes in gingival and anterior tooth recesses to form a preliminary try-in denture, which is fitted to a patient and adjusted to optimal dimensions. The adjusted try-in denture is then reproduced by further molding methods, producing the final denture.

Abstract: The invention relates to a method in which at a first location (A), such as a dental technician's laboratory or a dentist's surgery, digital image data (18) in the form of single images and/or image sequences are generated and these are transmitted to a second location (B), such as a production centre for denture parts, wherein the digital image data (18) and/or image sequences relate to information on the manufacture of denture parts (15). Furthermore, the invention relates to a scanning device for obtaining data records of dental models with a scanning appliance, such as a scanning head and with a camera, wherein remote data transmission means (8) are provided for transmitting digital image data (18) from the camera in the form of single images and/or image sequences to another location (B), such as a production centre.

Abstract: The invention relates to a specimen part (1) for creating a stress-free fit, a so-called passive fit, of implant-supported and/or abutment-supported bridges (2) and bars (3) by means of a CAD/CAM tool for the creation of restorations (5), and to a method for creating a restoration from a digital model (15) of a patient's jaw provided with at least two implants and/or abutments, wherein the model (15) is determined by means of an intraoral scan (14). In order to improve the precision of restorations and to shorten the production process, provision is made that the specimen part (1) per implant (4) and/or abutment has a scannable structure (6), preferably at a defined distance (7) and angle (8) to the implant (4) and/or abutment.

Abstract: A method is provided for designing and fabricating a removable partial denture (RPD) framework including clasp retainers configured for removable engagement with abutment teeth of a patient. The method includes obtaining an initial digital model of the RPD framework based on patient image data. For each clasp retainer, a set of relevant geometric parameters is identified, each relevant geometric parameter being provided with a nominal value, and a target value of dislodging force is provided. The method further includes performing a force analysis on the initial digital model to determine corrected values for the relevant geometric parameters of each clasp retainer such that when the corrected values are assigned to the relevant geometric parameters, the dislodging force matches its target value. The method also includes obtaining a corrected digital model based on the corrected values, and fabricating the RPD framework based on the corrected digital model.

Abstract: The invention relates to a method for producing a wax base or a prosthesis base for producing a dental prosthesis, with which a virtual CAD model of the dental prosthesis is used for the production of the physical dental prosthesis or the physical prosthesis base, wherein, from the CAD model of the dental prosthesis, a virtual model of the prosthesis base is calculated, characterized by the following chronological steps: A) Scanning in of at least one three-dimensional region of a physical model of the oral cavity situation of a patient and preparation of a first data record on the basis of this scan, or intra-oral scan of a three-dimensional region of the oral cavity situation of the patient and production of a physical model of the oral cavity situation of a patient on the basis of the intra-oral scan and preparation of a first data record on the basis of the intra-oral scan; B) application of a wax layer or a plastic layer onto the physical model of the oral cavity situation; D) calculation of a virtual

Abstract: The invention relates to a prosthesis base, which is made entirely or partially of a prosthesis material and/or wax and has on its top face at least one substantially custom-fit recess (3) for zonally receiving an artificial tooth (1). According to the invention at least one channel (5) is formed in the prosthesis base (2), which opens into said recess (3). Furthermore, the invention relates to a process for the substance-to-substance bond of an artificial tooth (1) to a prosthesis base (2), which is made entirely or partially of a prosthesis material and/or wax and has at least one substantially custom-fit recess (3) for zonally receiving said artificial tooth (1).

Abstract: A device and method for treating teeth, the device includes an elastomeric body, the elastomeric body including: an elastomer and an ionic fluoride compound.

Abstract: The invention provides an implantable system for managing urinary incontinence. The system includes a sling with an elongate body member having a proximal portion, a distal portion and an intermediate portion. The intermediate portion is configured to be positioned underneath urethra of a subject for providing an adequate support to prevent leakage of urine during a stress event. The system may include a pressure sensor communicatively coupled with the elongated body member and configured to be positioned in an abdominal cavity and adapted to sense an increase in intra-abdominal pressure. The pressure sensor generates a first signal that is indicative of a change in the intra-abdominal pressure upon occurrence of the pressure event. The system includes a processing circuit to process the signal sensed by the pressure sensor.

Abstract: The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. In another aspect, the pivotable fenestrations include a first perimeter, a band of flexible material attached and surrounding the first perimeter, and a second perimeter attached to and surrounding the band of flexible material. The first perimeter, band of flexible material, and second perimeter have a geometric shape.