Patents Issued in March 27, 2018
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Patent number: 9925350Abstract: A connector and tubing combination includes a tubing segment with an end piece, such as a tubing flange. The tubing flange can be secured within the connector by an outer sleeve and an inner sleeve of the connector. Both of the inner sleeve and the outer sleeve are located outside of the tubing flange and the tubing segment. In addition, the inner sleeve, outer sleeve and the tubing flange are mechanically connected.Type: GrantFiled: February 19, 2014Date of Patent: March 27, 2018Assignee: Fisher & Paykel Healthcare LimitedInventors: Brent Ian Laing, David John Sims, Mark Thomas O'Connor
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Patent number: 9925351Abstract: An aromatherapy device includes a housing forming two annular wells for retaining a scented fluid therein. Each well includes an insert positioned in the well to assist the retention of the fluid in the well by providing a second contact surface for the fluid to contact. The shape of the annular well and the viscosity of the fluid discourage the fluid from leaking out of the housing if laid on its side.Type: GrantFiled: June 24, 2015Date of Patent: March 27, 2018Inventor: Jennifer K. Keener
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Patent number: 9925352Abstract: A method of making a ready-to-use catheter assembly and a ready-to-use catheter are provided, which avoids any degradation of the catheter during sterilization. The method comprises: placing a catheter with a hydrophilic coating and a wetting fluid in a catheter package made of low moisture transmission material while the package is in a first condition wherein an insertable length of the hydrophilic coating of the catheter is not in contact with the wetting fluid, sterilizing the catheter package with the catheter and the wetting fluid by radiation sterilization while the catheter package is kept in a condition in which the insertable length is not in contact with the wetting fluid, transferring the catheter package with the catheter and the wetting fluid into a second condition, bringing the wetting fluid into contact with at least the insertable length and activating the insertable length via gravity and/or via inertia.Type: GrantFiled: September 9, 2014Date of Patent: March 27, 2018Assignee: WILLY RUSCH GMBHInventors: Denzell McBurney, Morgan Tierney, Ronald John Kelly
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Patent number: 9925353Abstract: A dual lumen cannula includes a first tube defining a return lumen and having a proximal end, a mid-portion and a distal end, wherein the distal end includes a return aperture. A second tube is coaxial with the first tube and has a proximal end and a distal end, wherein the distal end of the second tube is fixedly attached to the mid-portion of the first tube and wherein the distal end of the second tube includes a drainage aperture. A drainage lumen is defined by a space between the first tube and the second tube. A connector is attached to the proximal end of the second tube. The connector includes a reservoir for receiving a fluid from the proximal end of the second tube. The first tube extends through the connector and does not attach directly with the second tube at the connector, and the first tube remains substantially coaxial with the second tube throughout a length of the second tube.Type: GrantFiled: December 12, 2015Date of Patent: March 27, 2018Assignee: Nordson CorporationInventor: Frederick A Shorey
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Patent number: 9925354Abstract: A catheter or other elongated member can include an elongated inner portion, an elongated outer portion, a flex circuit ribbon comprising at least one conductor, and an electrical contact. The flex circuit ribbon can be situated between the inner portion and the outer portion. The inner portion and the outer portion can be (1) affixed together between portions of the flex circuit ribbon or (2) integrally formed such that masses of the inner and outer portions are joined together between portions of the flex circuit ribbon. The electrical contact can be configured to be exposed during use. The electrical contact can be situated at, or connected to, the at least one conductor of the flex circuit ribbon.Type: GrantFiled: October 23, 2013Date of Patent: March 27, 2018Assignee: Evergreen Medical Technologies, Inc.Inventors: Steven E. Scott, Jahn Stopperan, John Tracy, Greg Closser
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Patent number: 9925355Abstract: An intermittent catheter assembly and kit comprising an elongated introducer element formed of a flexible material adapted for insertion into a urethra during a catheterization procedure. The introducer element has at least one slit extending longitudinally along a substantial portion of its length. The catheter assembly also includes an applicator having an opening, and a sheath having a first end that is secured to the applicator about the opening. The sheath also has a second end defining a discharge opening which is inverted relative to the first end of the sheath to define inner and outer sleeve portions. The inner sleeve portion defines a flow path for urine through the discharge opening. The applicator receives the introducer element through the opening and extends the outer sleeve portion over an outer surface of the elongated introducer element to separate it from the urethra.Type: GrantFiled: March 14, 2013Date of Patent: March 27, 2018Assignee: Hollister IncorporatedInventors: Adam J. Foley, Jerome A. Henry, David Hannon
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Patent number: 9925356Abstract: A long catheter can be inserted into a patient while eliminating a need for a sterile field by incorporating the long catheter into an infusion tubing and carrying it in with an infusion. The long catheter has a structure that prevents it from leaving the infusion tubing when fully extended and therefore becomes a connector for fluids to transfer down the long catheter by infusion through the infusion tubing. Use of an adjustable seal connector allows the long catheter to be stopped at varying points during insertion and even to allow the long catheter to be reversed by pulling suction on the infusion tubing and retracting the long catheter back into the infusion tubing. The long catheter also remains within sterile confines of the infusion tubing and therefore is prevented from becoming contaminated.Type: GrantFiled: July 27, 2012Date of Patent: March 27, 2018Inventor: Matthew Dickson Reavill
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Patent number: 9925357Abstract: Disclosed is an assembly of parts for an endourological procedure, including a tubular sheath and an introducer, the tubular sheath being removably mounted on the introducer. The introducer comprises a security channel that is openable to shift a guidewire from a position inside the security channel to a position outside and next to the tubular sheath. Disclosed are also access sheaths and a method of performing an endourological procedure.Type: GrantFiled: March 12, 2014Date of Patent: March 27, 2018Assignee: Coloplast A/SInventors: Mathieu Lafitte, Laurent Pascal
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Patent number: 9925358Abstract: A catheter stabilization device having a release liner and a catheter stabilization member with a permeable first layer and a bottom surface having an adhesive interposed between the release liner and the first layer. The catheter stabilization member includes an elongated continuous retention strip coupled to the first layer is of a deformably rigid material operably configured to have a first static state with a first shape, a dynamic state, generated by an external force, with a second shape different than the first shape, and a second static state, after removal of the external force, with the second shape in a fixed configuration.Type: GrantFiled: March 20, 2017Date of Patent: March 27, 2018Inventor: Tamer Elsamahy
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Patent number: 9925359Abstract: A device and system for thermally affecting tissue that includes a balloon catheter with a reduced distal length for ease of navigation and that also includes a balloon that is more resistant to bursting and delamination. The balloon may include a proximal neck generally attached to an elongate body and a distal neck generally attached to a shaft disposed within the elongate body. The distal neck is turned inward to extend within the balloon chamber and the proximal neck may either extend within the chamber or extend proximally away from the balloon chamber. Alternatively, the device may include an inner balloon and an outer balloon, the distal necks of both being turned inward and extending within the inner balloon chamber. The proximal necks may both also be turned inward to extend within the chamber or the proximal neck of the outer balloon may extend away from the balloon chamber.Type: GrantFiled: March 21, 2014Date of Patent: March 27, 2018Assignee: Medtronic CryoCath LPInventor: Jean-Pierre Lalonde
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Patent number: 9925360Abstract: Devices and methods for regulating and directing bodily fluids from one region of a patient to another region are disclosed. In general, an apparatus is provided that can include an implantable shunt system and a system controller. The implantable shunt system can have an adjustable valve for regulating the flow of fluid, a sensor element for measuring a physiological characteristic of a patient, and an electromechanical valve actuator that can be adapted to adjust a resistance of the valve. The implantable shunt system can be in electrical communication with the system controller. The system controller can generally be adapted to receive a physiological characteristic of the patient and operate the electromechanical valve actuator to adjust a resistance of the valve. The apparatus can also include an external programming device that is in communication with the system controller.Type: GrantFiled: October 28, 2011Date of Patent: March 27, 2018Assignee: INTEGRA LIFESCIENCES SWITZERLAND SÀRLInventors: Lev Ludin, Christopher Mauge
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Patent number: 9925361Abstract: Method and apparatus for protecting and treating wounds are provided. A housing is adapted to be adhesively secured over the wound of an injured or infected person. The housing has an opening for access to the wound, and is further provided with inlet and outlet ports for the application of therapeutic materials. There is particularly provided a program for a closed looped system for such wound care. Additionally, the invention provides for a protective and treating cover for the eye, which can be either opaque or translucent. Additionally, a mechanism for accurately depositing eye drops without risking injury to the eye is also provided.Type: GrantFiled: January 3, 2014Date of Patent: March 27, 2018Inventor: Edward D. Lin
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Patent number: 9925362Abstract: A method and device for analyzing and treating tonal imperfections on human skin. The method has the steps of providing one or more nozzles and taking an image of skin adjacent the nozzles. A central processing unit calculates a plurality of local L values of the skin near nozzles and calculates a background L. The background L may be the arithmetic average, median, or mean of the plurality of local Ls near nozzles. Skin deviations are areas of skin where the absolute value of the difference between a local L and the background L, ?LM, is greater than a predetermined ?LS. Skin deviations are identified by this method and then treated with a treatment composition.Type: GrantFiled: June 11, 2015Date of Patent: March 27, 2018Assignee: The Procter & Gamble CompanyInventors: Thomas Elliot Rabe, Faiz Feisal Sherman, Stephan Gary Bush, Stephan James Andreas Meschkat
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Patent number: 9925363Abstract: A temporary disposable spacer device implantable in the human body for treatment of an infected bone seat or a joint seat includes a body provided with at least one coupling surface to the bone seat or joint seat to be treated and recesses along the coupling surface.Type: GrantFiled: April 30, 2015Date of Patent: March 27, 2018Inventor: Augusto Magagnoli
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Patent number: 9925364Abstract: The present invention relates to a catheter connector configured to provide an escape location for a liquid medium trapped therein. The catheter connector includes a body having a proximal end and a distal end. The proximal end includes a proximal end port for mating communication with a fluid delivery device. The body defines a hollow interior extending from the proximal end to the distal end. In one embodiment, the catheter connector includes an insert configured within the hollow interior of the connector. The insert defines a bore therethrough that is configured to receive a catheter at least partially therein. Further, the bore includes an interior wall and an exterior wall defining a thickness therebetween. The interior wall includes at least one discontinuity. Thus, when the catheter is inserted through the bore, at least one cavity is formed by the catheter and the at least one discontinuity of the insert.Type: GrantFiled: May 20, 2014Date of Patent: March 27, 2018Assignee: Avent, Inc.Inventors: Steve Saeed Khalaj, Kenneth Chen-Tse Hsu
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Patent number: 9925365Abstract: A needleless injection port assembly includes first and second body parts and a resilient barrier received within the body. A cannula attached to the first body part is received within an internal cavity of the resilient barrier. The resilient barrier is moveable between a less axially compressed first position in which fluid flow through the injection port assembly is prevented and a more axially compressed second position in which fluid flow through the assembly is allowed. An interference fit is provided between the resilient barrier and the cannula to seal against fluid flow through the cannula when the resilient barrier is in the first position. The cannula has an internal fluid passageway with a non-circular cross section providing increased fluid flow.Type: GrantFiled: June 21, 2017Date of Patent: March 27, 2018Assignee: RyMed Technologies, LLCInventors: Dana Wm. Ryan, Anthony E. Ryherd, James M. Kaiser
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Patent number: 9925366Abstract: Methods and devices for separating an implanted object, such as a pacemaker lead, from tissue surrounding such object in a patient's vasculature system. Specifically, the tissue separating device includes a handle, an elongate sheath and a circular cutting blade that may extend from the distal end of the sheath upon actuating the handle. The elongate sheath, particularly its distal end, includes a non-uniform wall thickness having one or more thicker portions in the outer sheath, particularly the outer cam member, and/or one or more thicker portions in an inner member disposed radially inward of the blade.Type: GrantFiled: March 13, 2014Date of Patent: March 27, 2018Assignee: The Spectranetics CorporationInventors: Kenneth P. Grace, Bruce A. Hoo
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Patent number: 9925367Abstract: A method of laparoscopically implanting an electrically stimulating lead proximate the lower esophageal sphincter (LES) of a patient includes delivering the lead through a port of a laparoscope inserted into the abdominal cavity of the patient through an incision in the abdominal wall. The stimulating electrode is implanted in or proximate the muscularis layer of the lower esophageal wall to treat esophageal reflux disease (GERD). The lead includes a needle and suture at its distal end for pulling the electrode into the muscular wall of the LES. Clips are applied to the suture attached to the distal end of the lead to prevent retrograde movement of the electrode. The lead also includes an anchoring member for anchoring the portion of the lead proximal to the electrode. The method and lead used with the method allow the surgeon to work within the confined anatomy present at the gastroesophageal junction and prevents backwards movement and dislodgment of the electrode.Type: GrantFiled: November 20, 2014Date of Patent: March 27, 2018Assignee: EndoStim, Inc.Inventors: Virender K. Sharma, Shai Policker, Paul V. Goode, Ofer Glasberg
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Patent number: 9925368Abstract: Disclosed is a carbon material for a neurostimulation electrode. The carbon material is composed of a carbon fiber. The carbon fiber has a thickness of 1 to 1000 ?m, a linear density of 0.01 to 5.00 g/cm, and an aspect ratio of 100 to 1,000,000. Particularly, the carbon fiber material can be obtained by dry spinning carbon nanotubes, followed by liquid-based densification. The carbon material can be used in the fields of deep brain stimulation, spinal cord stimulation, etc. Also disclosed are an electrode assembly and a neurostimulation device, each including the carbon material.Type: GrantFiled: June 3, 2014Date of Patent: March 27, 2018Assignee: INNOTHERAPY INC.Inventors: Seong Woo Ryu, Hae Shin Lee, Moon Sue Lee, Sun Ha Paek, Mi Young Koh
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Patent number: 9925369Abstract: Disclosed herein is an implantable lead configured to administer electrotherapy to a patient heart from an implantable pulse generator. The lead may include a lead body and an attachment structure. The lead body includes a bifurcated distal region including first and second lead body branches each terminating in a distal end. At least one of the first lead body branch or second lead body branch includes an electrode. The attachment structure couples together the distal ends of the first and second lead body branches. The attachment structure is configured to release such that the distal ends of the first and second lead body branches can decouple from each other.Type: GrantFiled: April 29, 2016Date of Patent: March 27, 2018Assignee: PACESETTER, INC.Inventors: Gene A. Bornzin, Didier Theret, Zoltan Somogyi
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Patent number: 9925370Abstract: The invention relates to a bipolar myocardial pacemaker electrode (1) consisting of a plug (2), a supply line (3), a cathode (4), an anode (5), surgical thread (7) and a fixation member (8), whereby the electrode (1) has an internal lumen and is freely movable on the thread (7); the thread (7) can be guided through the inner lumen of the electrode including the supply line and plug thereof, and distally supports the fixation member (8) in the form of a knot; the supply line (3) is externally insulated and has a distal cathode pole (4) tangentially arranged on the surface of the heart in the heart tissue (myocardium) in the usage position, wherein the cathode pole consists of a conically tapering coil and the supply line (3) has an anode pole (5) arranged proximally underneath the heart in the usage position.Type: GrantFiled: January 14, 2013Date of Patent: March 27, 2018Inventor: Peter Osypka
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Patent number: 9925371Abstract: A system is provided to determine whether an insulating layer of an implanted lead is damaged.Type: GrantFiled: March 17, 2016Date of Patent: March 27, 2018Assignee: The Spectranetics CorporationInventor: Kenneth P. Grace
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Patent number: 9925372Abstract: Apparatus (100) and method are disclosed for removing or reducing the number of particles in an enclosed atmosphere during intracorporeal procedures. The apparatus comprises a housing (180) adapted to be placed against the body on which a procedure is to be formed, a first electrode (140) external to the housing for contacting the body, an elongated electrically insulated probe (130) extending from the housing (180) and being insertable into an intracorporeal body cavity (C) in which a procedure is to be performed, a second electrode (150) at the free end of the probe, and circuit means (110) for generating voltage between said first and second electrodes. The method comprises applying a voltage between the electrodes sufficient to cause local ionization of particles within the body cavity such that they migrate away from the second electrode, thereby removing or reducing the number of particles generated during the procedure from the enclosed atmosphere at or around the site of the procedure.Type: GrantFiled: September 5, 2012Date of Patent: March 27, 2018Assignee: ASALUS MEDICAL INSTRUMENTS LIMITEDInventors: Francis Amoah, Dominic Griffiths
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Patent number: 9925373Abstract: A method improving or restoring neural function in a mammalian subject in need thereof, the method including: using an input receiver to record an input signal generated by a first set of nerve cells; using an encoder unit including a set of encoders to generate a set of coded outputs in response to the input signal; using the encoded outputs to drive an output generator; and using an output generator to activate a second set of nerve cells wherein the second set of nerve cells is separated from the first set of nerve cells by impaired set of signaling cells. In some embodiments, the second set of nerve cells produces a response that is substantially the same as the response in an unimpaired subject.Type: GrantFiled: March 17, 2016Date of Patent: March 27, 2018Assignee: CORNELL UNIVERSITYInventor: Sheila Nirenberg
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Patent number: 9925374Abstract: In one embodiment, a method includes implanting an implant entirely under the subject's skin. The implant includes a passive electrical conductor of sufficient length to extend from subcutaneous tissue located below one of a surface cathodic electrode and a surface anodic electrode to the tibial nerve. The surface electrodes are positioned in spaced relationship on the subject's skin, with one of the electrodes positioned over the pick-up end of the electrical conductor such that the portion of the current is transmitted through the conductor to the tibial nerve, and such that the current flows through the tibial nerve and returns to the other of the surface cathodic electrode and the surface anodic electrode. An electrical current is applied between the surface cathodic electrode and the surface anodic electrode to cause the portion of the electrical current to flow through the implant to stimulate the tibial nerve.Type: GrantFiled: June 24, 2009Date of Patent: March 27, 2018Assignee: Bioness Inc.Inventors: Arkady Glukhovsky, Mark L. Lindon
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Patent number: 9925375Abstract: A non-invasive device for facilitating therapy of patient suffering from the gastrointestinal system diseases or symptoms, and in particular suffering Gastroesophageal reflux disease (GERD). The device is positioned by the patient on the skin of the patient abdomen and electrically stimulates the abdomen muscles. This treating results in dynamic motions of the digestive system, which causes the treatment of various digestive symptoms or diseases.Type: GrantFiled: April 19, 2016Date of Patent: March 27, 2018Inventors: Mordechay Esh, Giora Arbel
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Patent number: 9925376Abstract: Techniques using electrical stimulation for treating an Autoimmune Disease by means of an implantable pulse generator and at least one electrode. An electrode lead is surgically implanted in a region of the insular cortex to deliver electrical stimulation. The at least one electrode lead and implantable pulse generator contain features that allow the electrical stimulation to be directed to specific volumes of the insular cortex, and ensure that non-therapeutic volumes do not receive electrical stimulation.Type: GrantFiled: February 1, 2017Date of Patent: March 27, 2018Assignee: ALEVA NEUROTHERAPEUTICSInventors: Ingo Hartig, Andre Mercanzini, Alain Jordan, Alexandre Michalis, Marc Boers, Alain Dransart
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Patent number: 9925377Abstract: A transcutaneous electrical-stimulation system includes a transcutaneous control module including a processor. The transcutaneous control module provides electrical-stimulation signals to electrode sets electrically-coupled to the transcutaneous control module. A first electrode set is electrically-coupled to the transcutaneous control module and is placed along patient skin over a first stimulation location. The first electrode set generates a first effective electric field suitable for transcutaneous stimulation of patient tissue at the first stimulation location. A second electrode set is electrically-coupled to the transcutaneous control module and is placed along patient skin over a second stimulation location. The second electrode set generates a second effective electric field suitable for stimulating patient tissue at the second stimulation location.Type: GrantFiled: September 22, 2015Date of Patent: March 27, 2018Assignee: Boston Scientific Neuromodulation CorporationInventors: Michael A. Moffitt, Stephen Carcieri
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Patent number: 9925378Abstract: Methods and systems for electrical stimulation can include obtaining a biosignal of the patient; altering at least one stimulation parameter of an electrical stimulation system in response to the biosignal; and delivering an electrical stimulation current to one or more selected electrodes of the electrical stimulation system using the at least one stimulation parameter. In some embodiments, a power spectrum is determined from the biosignal. In some embodiments, the biosignal is at least two different biosignals measured at the same or different locations on the patient and a coherence, correlation, or association between the two biosignal is determined.Type: GrantFiled: September 22, 2015Date of Patent: March 27, 2018Assignee: Boston Scientific Neuromodulation CorporationInventors: Michael A. Moffitt, Hemant Bokil
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Patent number: 9925379Abstract: A computer implemented method and system is provided for managing neural stimulation therapy. The method comprises under control of one or more processors configured with program instructions. The method delivers a series of candidate stimulation waveforms having varied stimulation intensities to at least one electrode located proximate to nervous tissue of interest. A parameter defines the candidate stimulation waveforms is changed to vary the stimulation intensity. The method identifies a first candidate stimulation waveform that induces a paresthesia-abatement effect, while continuing to induce a select analgesic effect. The method further identifies a second candidate stimulation waveform that does not induce the select analgesic effect. The method sets a stimulation therapy based on the first and second candidate stimulation waveforms.Type: GrantFiled: December 22, 2015Date of Patent: March 27, 2018Assignee: Pacesetter, Inc.Inventors: Xiaoyi Min, Alexander Kent, Richard Williamson
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Patent number: 9925380Abstract: A method of providing therapy to a patient having a medical condition comprises delivering electrical stimulation energy to the spinal cord of the patient in accordance with a stimulation program that preferentially stimulates dorsal horn neuronal elements over dorsal column neuronal elements in the spinal cord. The delivered electrical stimulation energy generates a plurality of electrical fields having different orientations that stimulate the dorsal horn neuronal elements.Type: GrantFiled: May 26, 2017Date of Patent: March 27, 2018Assignee: Boston Scientific Neuromodulation CorporationInventors: Michael A. Moffitt, Bradley Lawrence Hershey, Changfang Zhu
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Patent number: 9925381Abstract: An implantable pulse generator that includes a current source/sink generator is disclosed herein. The current source/sink generator includes a current drive differential amplifier. The current driver differential amplifier is configured to selectively source current to, or sink current from a target tissue. The current drive differential amplifier includes an inverting input and a non-inverting input. One of the inputs of the current drive differential amplifier is connected to a virtual ground, and the other is connected to a current command. A stimulation controller can supply a voltage to the other of the inputs of the current drive differential amplifier to select either current sourcing or current sinking.Type: GrantFiled: January 24, 2017Date of Patent: March 27, 2018Assignee: AXONICS MODULATION TECHNOLOGIES, INC.Inventor: Rabih Nassif
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Patent number: 9925382Abstract: A computer implemented system and method facilitates a cycle of generation, sharing, and refinement of volumes related to stimulation of anatomical tissue, such as brain or spinal cord stimulation. Such volumes can include target stimulation volumes, side effect volumes, and volumes of estimated activation. A computer system and method also facilitates analysis of groups of volumes, including analysis of differences and/or commonalities between different groups of volumes.Type: GrantFiled: August 9, 2012Date of Patent: March 27, 2018Assignee: Boston Scientific Neuromodulation CorporationInventors: Keith Carlton, Jim Cassidy, Dean Chen, Michael A. Moffitt, Dennis Zottola
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Patent number: 9925383Abstract: The disclosure relates to a device including a circuit for adjusting the energy of the stimulation pulses, independently controlling the pulse width and the voltage of each stimulation pulse. An iterative search algorithm for determining the optimum energy includes changing both the pulse width and voltage at each new pulse delivered, by setting a high energy value and a low energy value, and delivering a stimulation pulse with the low energy value. A capture test is then carried out. In the presence of a capture, a current iteration is complete and a new iteration is done with the current low energy as a new high energy value. In the absence of capture, the algorithm is terminated with selection of the last energy value that produced the capture as the value of optimum energy.Type: GrantFiled: January 11, 2016Date of Patent: March 27, 2018Assignee: SORIN CRM SASInventor: Alaa Makdissi
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Patent number: 9925384Abstract: An implantable neural stimulator method for modulating excitable tissue in a patient including: implanting a neural stimulator within the body of the patient such that one or more electrodes of the neural stimulator are positioned at a target site adjacent to or near excitable tissue; generating an input signal with a controller module located outside of, and spaced away from, the patient's body; transmitting the input signal to the neural stimulator through electrical radiative coupling; converting the input signal to electrical pulses within the neural stimulator; and applying the electrical pulses to the excitable tissue sufficient to modulate said excitable tissue.Type: GrantFiled: September 1, 2016Date of Patent: March 27, 2018Assignee: Micron Devices LLCInventors: Laura Tyler Perryman, Patrick Larson, Chad Andresen
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Patent number: 9925385Abstract: Timing channel circuitry for controlling stimulation circuitry in an implantable stimulator is disclosed. The timing channel circuitry comprises a addressable memory. Data for the various phases of a desired pulse are stored in the memory using different numbers of words, including a command indicative of the number of words in the phase, a next address for the next phase stored in the memory, and a pulse width or duration of the current phase, control data for the stimulation circuitry, pulse amplitude, and electrode data. The command data is used to address through the words in the current phase via the address bus, which words are sent to a control register for the stimulation circuitry. After the duration of the pulse width for the current phase has passed, the stored next address is used to access the data for the next phase stored in the memory.Type: GrantFiled: October 10, 2016Date of Patent: March 27, 2018Assignee: Boston Scientific Neuromodulation CorporationInventors: Paul J. Griffith, Goran N. Marnfeldt, Jordi Parramon
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Patent number: 9925386Abstract: Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.Type: GrantFiled: March 2, 2016Date of Patent: March 27, 2018Assignee: Cardiac Pacemakers, Inc.Inventors: Roger Hastings, William J. Drasler, Daniel M. Lafontaine, Anupama Sadasiva, Scott R. Smith
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Patent number: 9925387Abstract: A remote alarm for use with a wearable defibrillator. The remote alarm may be a wearable remote device including a strap for disposing the wearable remote device on a wrist of a patient and communications circuitry disposed in the wearable remote device to wirelessly communicate with the wearable defibrillator. The wearable remote device may be configured to receive alarms, voice messages and prompts issued by the wearable defibrillator and to repeat those alarms, voice messages and prompts in a manner that can more easily be perceived by a patient wearing the wearable defibrillator or a bystander. The wearable remote device may further be configured to take certain actions depending upon the content of the communication, such as sending a telephone message to alert emergency personnel to the identity, location and medical condition of the patient, or sending an email to a friend, caregiver, or relative.Type: GrantFiled: December 22, 2014Date of Patent: March 27, 2018Assignee: ZOLL Medical CorporationInventors: Thomas E. Kaib, Shane S. Volpe, Richard A. Rattanni
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Patent number: 9925388Abstract: Devices and methods for directing a magnetic field into a body party of a subject are provided. The devices include at least one electromagnetic coil, a magnetic core or yoke, and a pair of flux concentrators. The flux concentrators are separated by a gap into which the body part fits and through which the flux concentrators focus the magnetic field. The devices allow magnetic fields to be transmitted through the gap with higher intensity at greater distances from the device than possible with previous designs. The methods of using such devices allow the delivery of magnetic fields with higher intensity to the interior of a body part without exposing interposed proximal regions to magnetic fields of unduly high intensity. The devices and methods are useful for deep transcranial magnetic stimulation of the brain to treat various medical conditions.Type: GrantFiled: March 26, 2015Date of Patent: March 27, 2018Assignee: Northeastern UniversityInventors: Parisa Andalib, Francesca Scire Scappuzzo, Vincent Harris
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Patent number: 9925389Abstract: The present application relates to a shape memory alloy hypotube as well as use thereof in a blood vessel optical fiber guide wire. The hypotube comprises several spiral coils. This hypotube is made from a shape memory alloy such that its diameter varies over temperature. Thus, it can closely wrap an axial fiber disposed therein. Through phase change properties and shape memory properties of the memory alloy, the inner diameter of the hypotube changes over temperature. The hypotube produces two functions: making a wrapping expand and tight binding fixed. The shape memory alloy hypotube can improve the strength and safety of optical fiber guide wire. The hypotube can easily enter the blood vessel of human body. Further, the conventional winding process can be simplified.Type: GrantFiled: May 25, 2017Date of Patent: March 27, 2018Inventor: Hua Shang
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Patent number: 9925390Abstract: A protective case for a mobile electronic device is provided. The case includes at least one light emitting diode that emits electromagnetic radiation in the range of UV-C light for sanitizing contaminated surfaces. The case also includes additional LEDs that emit light at wavelengths known to have a therapeutic effect such as a blue light for treating seasonal affective disorder. The LEDs are provided in a separate encasement that is detachable from the protective cover configured to receive and protect the mobile electronic device. A short-range wireless receiver is included to communicate with an application installed on the mobile electronic device for controlling the activation, intensity, duration and mode of the LEDs including predetermined treatment or sanitization protocols.Type: GrantFiled: September 15, 2016Date of Patent: March 27, 2018Assignee: ETS Technologies, LLCInventor: Shaul Yehezkel
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Patent number: 9925391Abstract: A system for facilitating creation of a patient treatment plan includes components configured to receive at least one feature associated with patient data and search a database of previously planned radiation treatments to identify one or more matching plans from the database based on the at least one feature. Parameters corresponding to the identified matching treatment plans may be used to facilitate creation of the patient treatment plan.Type: GrantFiled: June 20, 2014Date of Patent: March 27, 2018Assignee: Siris Medical, Inc.Inventors: Colin Carpenter, Ran Davidi, Nicholas Mourlas, Todd Atwood
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Patent number: 9925392Abstract: Disclosed is a medical data processing method of determining a transformation for determining a breathing state-dependent geometry of an anatomical body part of a patient's body, the method comprising executing, on at least one processor of at least one computer, steps of: a) acquiring, at a processor, planning image data describing a set of tomographic medical planning images describing each a different part of the anatomical body part in the same respiratory state called reference planning respiratory state (y), wherein the anatomical body part is subject to respiratory movement and wherein the planning images comprise a planning image called reference planning image describing a part of the anatomical body part which is called reference planning body part; b) acquiring, at a processor, breathing image data describing a set (1) of tomographic medical breathing images of the anatomical body part, wherein the breathing images comprise a reference breathing image (A) describing the reference planning body partType: GrantFiled: August 27, 2015Date of Patent: March 27, 2018Assignee: Brainlab AGInventor: Stefan Vilsmeier
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Patent number: 9925393Abstract: An apparatus for determining a contour of a treatment region in a patient includes a computer processor to receive input regarding a contour of at least one organ-at-risk (OAR) adjacent to the treatment region; receive input regarding an initial contour of the treatment region; predict a radiation toxicity to the at least one OAR based on the contour of the at least one OAR, the initial contour of the treatment region, and a radiation treatment regimen; determine whether the predicted radiation toxicity exceeds a threshold; and determine a contour of the treatment region by iteratively modifying the initial contour of the treatment region, and any subsequent modified contours of the treatment region, until a stopping condition is satisfied. The stopping condition can be a preselected number of iterations or that the predicted radiation toxicity using the contour in place of the initial contour is first calculated is below said threshold.Type: GrantFiled: March 14, 2016Date of Patent: March 27, 2018Assignees: KABUSHIKI KAISHA TOSHIBA, TOSHIBA MEDICAL SYSTEMS CORPORATION, The Johns Hopkins UniversityInventors: Minoru Nakatsugawa, John Wayne Haller, Robert Andrew Davey, Rachel-Louise Kvertus Koktava, Kosuke Sakaue, Todd McNutt, Harry Quon, Scott Patrick Robertson, Zhi Cheng
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Patent number: 9925394Abstract: In a method of detecting the health of a motion axis in a radiation system including a motor operable to move a load between a first end and a second end, data on an electrical parameter of the motor is collected as the motor moves in the certain range. At least one indicator of the electrical parameter including a maximum, a minimum, an average, and a standard deviation of the electrical parameter is determined and compared with a provided value or range of values indicative of the health of the axis. The health of the motion axis is determined using the comparison of the at least one indicator and the provided value or range of values.Type: GrantFiled: June 8, 2011Date of Patent: March 27, 2018Assignee: Varian Medical Systems, Inc.Inventor: Robert T. Wiggers
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Patent number: 9925395Abstract: A system includes a patient support and an outer gantry on which an accelerator is mounted to enable the accelerator to move through a range of positions around a patient on the patient support. The accelerator is configured to produce a proton or ion beam having an energy level sufficient to reach a target in the patient. An inner gantry includes an aperture for directing the proton or ion beam towards the target.Type: GrantFiled: July 28, 2016Date of Patent: March 27, 2018Assignee: Mevion Medical Systems, Inc.Inventors: Kenneth P. Gall, Stanley J. Rosenthal, Gordon D. Row, Michael J. Ahearn
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Patent number: 9925396Abstract: The invention relates to adhesive articles containing at least one colorant and/or at least one active agent as well as to methods of using such articles on mucosis or keratin materials to achieve a desired result or benefit and to methods of making such adhesive articles.Type: GrantFiled: January 30, 2009Date of Patent: March 27, 2018Assignee: L'OREALInventors: Guillaume Kergosien, William Meathrel
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Patent number: 9925397Abstract: The present invention is directed to a composition for the conditioning of a dental mineralized surface and/or a dental implant and/or for increasing the hydrophilicity of a dental implant having a metal containing surface. The composition comprises EDTA in a concentration of 21-55% by weight and having a pH of 9.0 or above. The high pH of the composition allows more EDTA to be dissolved and the composition is useful for the conditioning of mineralized dental surfaces and/or surfaces of dental implants. The composition of the invention may thus be used for the conditioning of mineralized dental surfaces and dental implant surfaces in order to remove e.g. biofilm, debris, bacteria, bacterial toxins etc and/or for increasing the hydrophilicity of an implant having a metallic surface. The invention is also directed to a kit comprising the composition of the invention and a device to apply the composition to a surface in need of conditioning.Type: GrantFiled: May 24, 2011Date of Patent: March 27, 2018Assignee: Straumann Holding AGInventor: Daniel Fehr
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Patent number: 9925398Abstract: The present application discloses angiogenic peptides that cause intracellular calcium release in target cells and thereby induce proliferation, migration, and capillary-like tube formation in primary cultured endothelial cells. The angiogenic peptides can be used for preventing and/or treating angiognesis-related conditions, especially wound healing, treating foot and leg ulcers in a subject, etc. In addition, the angiogenic peptides can be used for cosmetics a constituent of cosmetics for aged skin, for examples, anti-wrinkle and skin whitening.Type: GrantFiled: April 23, 2009Date of Patent: March 27, 2018Assignee: NOVACELL TECHNOLOGY INC.Inventor: Taehoon Lee
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Patent number: 9925399Abstract: An emergency breathing apparatus for use in case of burial by an avalanche is described. The breathing apparatus may include a telescoping body configured to transition between a collapsed and extended configuration. The body may include a plurality of tubular members. The breathing apparatus may include a breathing port on one end of the device, a plurality of apertures on the opposite end of the device, and an internal lumen that fluidly connects the breathing port with the plurality of apertures. The breathing apparatus may include a spring assembly, a motorized extension mechanism, a pneumatic extension mechanism, or a combination of these devices, that are configured to extend the body from a collapsed configuration to an extended configuration.Type: GrantFiled: March 1, 2017Date of Patent: March 27, 2018Inventor: Sophie Rose Goldberg