Patents Issued in July 5, 2018
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Publication number: 20180184918Abstract: A method for measuring sound from vortices in the carotid artery comprising: first and second quality control provisions, wherein the quality control compares detected sounds to pre-determined sounds, and upon confirmation of the quality control procedures, detecting sounds generated by the heart and sounds from vortices in the carotid artery for at least 30 seconds.Type: ApplicationFiled: June 15, 2016Publication date: July 5, 2018Applicant: CVR GLOBAL INC.Inventors: Bret Kline, Peter Bakema, Young Truong, Richard Finlayson, Orville Day
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Publication number: 20180184919Abstract: A blood pressure ratio calculation device is a device for calculating a maximum-minimum blood pressure ratio corresponding to a ratio between a maximum blood pressure value and a minimum blood pressure value of an inspection target, and includes an input unit for inputting a relative blood pressure waveform corresponding to temporal change in relative blood pressure of the inspection target, a spectrum generation unit for generating a relative blood pressure waveform spectrum by performing Fourier transform on the relative blood pressure waveform, and an analysis unit for calculating the maximum-minimum blood pressure ratio on the basis of the relative blood pressure waveform spectrum.Type: ApplicationFiled: March 8, 2016Publication date: July 5, 2018Applicant: HAMAMATSU PHOTONICS K.K.Inventors: Tomoya NAKAZAWA, Rui SEKINE
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Publication number: 20180184920Abstract: A novel and useful system and method for generating user feedback related to the quality of the placement and contact of a blood pressure sensor on a user's body. The sensor is incorporated in a wearable blood pressure measurement device that is capable of analyzing and providing feedback regarding the quality of placement and contact of the pressure sensor array. The wearable includes a pressure sensor array for monitoring blood pressure, means for attaching the pressure sensor to a user's body for measuring a region, a processor operative to record pressure signals from said sensor array and to calculate quality of pressure sensor contact to measurement area score, and a display operative to determine and display the quality of the placement and contact of the pressure sensor. A quality metric indicating the quality of the placement and contact of the pressure sensor is provided as feedback to the user.Type: ApplicationFiled: December 19, 2017Publication date: July 5, 2018Applicant: LiveMetric (Medical) S.A.Inventors: Adi Efraim Joseph Rabinovich, Nir Efraim Joseph Tal, Tomer Bentzion, Ori Hay
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Publication number: 20180184921Abstract: Apparatuses, systems, and methods described herein can enable reliable estimation of pulse transit time (PTT) for a user in motion for cuffless blood pressure estimation. In one embodiment, a method involves receiving an electrocardiographic (ECG) signal and a photoplethysmographic (PPG) signal and detecting R-wave peaks in the ECG signal. The method further involves identifying multiple segments of the PPG signal based on detection of the R-wave peaks of the ECG signal, wherein a given segment of the PPG signal comprises multiple samples and is aligned with a corresponding R-wave. The method also involves generating an averaged PPG wave based on the multiple segments of the PPG signal, wherein a given element of the averaged PPG wave comprises an average of corresponding elements from the multiple segments of the PPG signal, and computing the blood pressure value based on the averaged PPG wave.Type: ApplicationFiled: December 29, 2016Publication date: July 5, 2018Inventors: Amit S. BAXI, Vincent S. MAGESHKUMAR
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Publication number: 20180184922Abstract: A viscoelastic characteristics acquisition device is a device that acquires viscoelastic characteristics of a blood vessel of an inspection target, and includes a pulse wave acquisition unit that acquires a time waveform corresponding to a volume pulse wave of the inspection target, a spectrum acquisition unit that acquires a volume pulse wave spectrum by performing Fourier transform on the time waveform, an input unit to which values corresponding to maximum blood pressure and minimum blood pressure of the inspection target are input, and an analysis unit that acquires the viscoelastic characteristics on the basis of the values corresponding to the maximum blood pressure and the minimum blood pressure and the volume pulse wave spectrum at a frequency equal to or higher than a frequency corresponding to the pulse of the inspection target.Type: ApplicationFiled: March 8, 2016Publication date: July 5, 2018Applicant: HAMAMATSU PHOTONICS K.K.Inventors: Tomoya NAKAZAWA, Rui SEKINE
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Publication number: 20180184923Abstract: A novel and useful pressure sensor array incorporating sensor elements constructed from electrically conductive film as a substrate. Examples of commercially available electrically conductive (i.e. piezoresistive) film include Velostat and Linqstat. A wearable device is described incorporating an array of pressure sensors with flexible properties and a biocompatible material interface between the sensor elements and a user's skin. The pressure sensor array uses the electrically conductive film as a substrate and places a pair of conductors in a suitable configuration to form individual sensor elements. The sensor elements detect the change in resistance of the electrically conductive film when pressure is applied thereto. The sensor elements may be implemented in an interdigitated or opposing configuration. The sensor array also comprises a mechanical interface on top of the sensor elements for transferring or focusing the applied pressure to the electrically conductive film.Type: ApplicationFiled: November 30, 2017Publication date: July 5, 2018Applicant: LiveMetric (Medical) S.A.Inventors: Nir Efraim Joseph Tal, Adi Rabinovich, Tomer Bentzion
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Publication number: 20180184924Abstract: A blood pressure device having a cylindrical drum cuff housing adapted to measure the circumference of either a right or left arm and administer a blood pressure test. The drum cuff housing is connected to a knuckle support assembly adapted to provide freedom of movement for postural positioning before and during the blood pressure test.Type: ApplicationFiled: December 29, 2017Publication date: July 5, 2018Inventors: Bjorn McMillan, David Erceg, Jeffrey D. Flammer, Rene Nunez, Colin Kenneth Hill, John R. Collins
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Publication number: 20180184925Abstract: A bodily information measurement apparatus includes a band-shaped belt to be wrapped around a measurement site; a main body that is connected to a base end portion in the lengthwise direction of the belt and on which a pressure detection unit and a fluid supply unit are mounted; and a fastening unit for fastening the base end portion and the leading end portion of the belt. The belt is formed by stacking an outer circumferential layer and a fluid bladder for compressing the measurement site. The bodily information measurement apparatus is attached to the measurement site due to the base end portion and the leading end portion being fastened by the fastening portion in a state in which the fluid bladder and the leading end portion of the belt overlap.Type: ApplicationFiled: February 28, 2018Publication date: July 5, 2018Applicant: OMRON HEALTHCARE Co., Ltd.Inventors: Yoshihide Tokko, Ryosuke Doi, Yuma Adachi, Chisato Tawara, Minoru Taniguchi, Masayuki Fukutsuka, Eisuke Yamazaki
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Publication number: 20180184926Abstract: A blood pressure monitor cuff is formed by stacking an outer circumferential layer arranged on a side opposite to that of a measurement site and a fluid bladder arranged on the measurement site side. The outer circumferential layer and the fluid bladder are formed of an elastomer material. Two edge portions in a lengthwise direction of the outer circumferential layer protrude in a thickness direction toward the measurement site. The fluid bladder includes a base layer that opposes the outer circumferential layer and a top layer overlapping with the base layer, and the edge portions of the base layer and the top layer are welded together forming a bladder shape. Additional sheets are welded in the thickness direction to the welded edge portions of the top layer and the base layer. The fluid bladder is arranged between the two edge portions of the outer circumferential layer in the width direction.Type: ApplicationFiled: February 28, 2018Publication date: July 5, 2018Applicant: OMRON HEALTHCARE Co., Ltd.Inventors: Ryosuke Doi, Chisato Tawara, Takayuki Matsuoka, Yuichiro Arima, Yoshihide Tokko, Minoru Taniguchi, Yuma Adachi, Masayuki Fukutsuka
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Publication number: 20180184927Abstract: A real-time heart rate detection method for use in a real-time heart rate detection system includes: (A) emitting light to a finger to generate reflected light; (B) receiving the reflected light via a sensing unit, to generate at least one initial fingerprint image; (C) generating plural initial waveform information according to the at least one initial fingerprint image; (D) selecting one among plural different bandpass filters, to filter the initial waveform information; (E) calculating an initial heart rate based upon the filtered initial waveform information; (F) checking and computing a frequency range of the obtained initial heart rate, to determine which one of the plural bandpass filters is the most preferable bandpass filter; (G) outputting a final heart rate; and repeating the step (A) to the step (G). The step (G) and the step (F) are performed at least partially in parallel.Type: ApplicationFiled: December 29, 2017Publication date: July 5, 2018Inventors: Chu-Hsin Chang, Jun-Shian Hsiao, Ching-Lung Ti, Chun-Fu Lin, Hui-Min Tsai
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Publication number: 20180184928Abstract: A system which includes a first sensor placed proximate to a perfusion field of an artery receiving blood which emanates from the cranial cavity is configured to monitor pulsations of the artery receiving blood which emanates from the cranial cavity artery. A second sensor placed proximate to a perfusion field of an artery which does not receive blood emanating from the cranial cavity configured to monitor pulsations of the artery which does not receive blood emanating from the cranial cavity. A third sensor configured to monitor pulsations of a distal artery. A processing system responsive to signals from the first, second, and third sensors is configured to determine intracranial pressure.Type: ApplicationFiled: February 20, 2018Publication date: July 5, 2018Inventor: Anna M Galea
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Publication number: 20180184929Abstract: Methods and apparatus for measuring pressure in a patient are provided which may include any number of features. One feature is a pressure measurement system comprising a pressure source, a compliant bladder, a catheter in communication with the pressure source, pressure sensors, and a controller configured to determine a pressure within the compliant bladder. The pressure measurement system can inflate the compliant bladder with gas or air to determine a pressure within a patient. In one embodiment, the pressure measurement system measures pressure within a peritoneal cavity.Type: ApplicationFiled: February 14, 2018Publication date: July 5, 2018Inventors: Daniel R. Burnett, Byron Reynolds, Brian M. Neil, Gregory W. Hall, Paul B. Guerra
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Publication number: 20180184930Abstract: The reconstruction of the current dipole sources in a portion of a body, such as a heart, from measured magnetic field data on a same plane near the heart is accomplished here. In embodiments, reconstruction of current dipole sources is accomplished by calculating the positions of the possible current dipoles in the heart with respect to the measured data plane and by converting a set of non linear equations to a set of linear equations.Type: ApplicationFiled: January 2, 2017Publication date: July 5, 2018Inventor: Xuan Zhong Ni
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Publication number: 20180184931Abstract: An ECG system identifies and annotates cardiac electrophysiological signals in an ECG waveform from harmonic waveforms. Electrical impulses are received from a beating heart. The electrical impulses are converted to an ECG waveform. The ECG waveform is converted to a frequency domain waveform, which, in turn, is separated into two or more different frequency domain waveforms, which, in turn, are converted into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms. The plurality of subwaveforms and discontinuity points are compared to a database of subwaveforms and discontinuity points for normal and abnormal patients. At least one subwaveform or one or more discontinuity points are identified as a normal or abnormal electrophysiological signal of the ECG waveform from the comparison. The ECG waveform is displayed along with one or more markers at a location of the at least one subwaveform or one or more discontinuity points.Type: ApplicationFiled: February 26, 2018Publication date: July 5, 2018Inventors: Guangren Chen, Rong Yang, Zhongnong Jiang
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Publication number: 20180184932Abstract: A noise detection sensor structure provides hardware-assisted real-time artifact detection on a live bio signal of interest while that signal is being recorded. The structure is configured to detect and analyze the type of external noise, and to use information about the noise type (such as noise level, frequency range of noise, noise source) to improve signal quality and usability of the bio signal. Different algorithms can be used for each noise type detected. In some example cases, for instance, the structure is configured to at least one of extract noise from measurement signal, synchronize measurement with noise signal, change the software filter or analysis algorithm, change gain/filter settings of noise mitigation circuitry, and prompt user to assist as needed, based on the detected noise. Bad signal epochs can be discarded prior to recording, to efficiently use storage. Separate channel(s)/sensor(s) can be used, with different filtering/gain schemes, for noise detection.Type: ApplicationFiled: December 29, 2016Publication date: July 5, 2018Applicant: INTEL CORPORATIONInventors: ESA SAUNAMAKI, MARKUS OSA
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Publication number: 20180184933Abstract: A wearable cardioverter defibrillator (WCD) including a support structure configured to be worn by an ambulatory patient, an energy storage module configured to store an electrical charge, a discharge circuit coupled to the energy storage module, electrodes configured to render an electrocardiogram (ECG) signal of the patient while the patient is wearing the support structure, a user interface configured to output an alarm in response to a noise alarm signal, and a processor. The processor is configured to receive the ECG signal, determine whether noise is present on the ECG signal, determine from the ECG signal whether a shock criterion is met, and cause the user interface to generate the noise alarm signal when the noise is present on the ECG signal and the shock criterion is met and not generate the noise alarm signal when noise is present on the ECG signal and the shock criterion is not met.Type: ApplicationFiled: January 3, 2018Publication date: July 5, 2018Inventors: Joseph L. Sullivan, Jaeho Kim
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Publication number: 20180184934Abstract: An ambulatory medical device including a plurality of electrodes configured to be disposed at spaced apart positions about a patient's body, an electrode signal acquisition circuit, and a monitoring circuit. The acquisition circuit has a plurality of inputs each electrically coupled to a respective electrode of the plurality of electrodes and is configured to sense a respective signal provided by a plurality of different pairings of the plurality of electrodes. The monitoring circuit is electrically coupled to an output of the acquisition circuit and is configured to analyze the respective signal provided by each of the plurality of different pairings and to instruct the acquisition circuit to select at least one of the plurality of different pairings to monitor based on at least one of the quality of the respective signal, a phase difference between the respective signal and that of other pairings, a position of electrodes relative to the patient's body, and other criteria.Type: ApplicationFiled: February 20, 2018Publication date: July 5, 2018Inventors: Thomas E. Kaib, Shane S. Volpe, John D. Macho
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Publication number: 20180184935Abstract: A method and system for neuro-feedback training are disclosed. According to certain embodiments, the method may include receiving, by a processor via a communication network, a brainwave signal measured by at least one sensor attached to a user. The method may also include determining, by the processor, a frequency distribution of the brainwave signal. The method may also include determining, by the processor, a first value indicative of an amount of the brainwave signal within a first frequency band. The method may also include generating, by the processor based on the first value, a first control signal to actuate a target device wirelessly connected to the processor. The method may further include transmitting, by the processor via the communication network, the first control signal to the target device.Type: ApplicationFiled: January 4, 2017Publication date: July 5, 2018Applicant: BrainCo Inc.Inventors: Bicheng HAN, Tianhe Wang, Max Newlon, Jianlin Zhou, Zhaoyi Yang, Bifei Liu, Nenghui Fang, Fangzhou Xia, Junqing Qiao, Sirui Zou, Xipeng Guo, Siwei Yao, Samuel James Prentice, Shiwei Wang
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Publication number: 20180184936Abstract: A method and system for neuro-feedback training are disclosed. According to certain embodiments, the method may include receiving, by a processor via a communication network, a brainwave signal measured by at least one sensor attached to a user. The method may also include determining, by the processor, a frequency distribution of the brainwave signal. The method may also include determining, by the processor, a reward in a video game when at least one first value indicative of an amount of the brainwave signal within a first frequency band meets a first criterion. The method may further include providing, to the user, a first feedback signal indicative of the reward.Type: ApplicationFiled: January 4, 2017Publication date: July 5, 2018Applicant: BrainCo Inc.Inventors: BICHENG HAN, TIANHE WANG, MAX NEWLON, JOANNE WYLIE, CHENGBANG ZHOU, JIANLIN ZHOU, XIANG YU, BOWEI HUANG, ZHAOYI YANG, Xipeng Guo, Sirui Zou, Siwei Yao
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Publication number: 20180184937Abstract: There is provided a method for simulating at least one wet electroencephalogram (EEG) signal from at least one dry EEG signals, comprising: receiving at least one dry EEG signal measured by dry EEG electrode(s) applied to locations on a head of a patient corresponding to at least one of temporal lobe or frontal lobe, computing at least one simulated wet EEG signal by applying a trained statistical model based on at least one dry EEG signal, the at least one simulated wet EEG signal simulating wet EEG signals measured by a wet EEG electrode applied to at least one location corresponding to at least one of: central, parietal lobe, and occipital lobe, and providing the at least one simulated wet EEG signal for adjusting feedback of a neurofeedback treatment applied by a neurofeedback device.Type: ApplicationFiled: January 3, 2018Publication date: July 5, 2018Inventors: Aziz KADDAN, Anas ABU MUKH, Shiri SIMON
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Publication number: 20180184938Abstract: The present invention relates to determining a neural respiratory drive (NRD) in patients with chronic obstructive pulmonary disease (COPD) based on surface electromyography measurements taken from the intercostal muscles on the chest of a subject (100).Type: ApplicationFiled: May 31, 2016Publication date: July 5, 2018Inventors: Alan James DAVIE, Sandrine Magali Laure DEVOT, Rene Martinus Maria DERKX, Jakob VAN DE LAAR
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Publication number: 20180184939Abstract: A disposable adhesive substrate, a medical device and a charging station are provided. In particular the substrate may be adapted to be arranged on the medical device, which correspondingly may be charged in the charging station. The medical device may be used for monitoring and treatment of bruxism.Type: ApplicationFiled: June 29, 2016Publication date: July 5, 2018Inventors: Christian Christiansen, Morten Haugland, Tommy Jacobsen, Karsten Videbæk
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Publication number: 20180184940Abstract: An orientation tracking device includes a memory for storing data therein including magnetic reference data relating to the direction of a static magnetic field of a magnetic imaging scanner in a selected principle co-ordinate frame and earth gravitational reference data relating to the direction of the gravitational field of the earth in the principle co-ordinate frame. The device also includes an accelerometer, a magnetometer and a communication module. A processor is connected to the accelerometer, the magnetometer and communication module and is adapted for receiving from the magnetometer a measurement of a magnetic field vector in a co-ordinate frame of the orientation tracking device, within the magnetic imaging scanner in which the orientation tracking device is placed in use. The processor further receives from the accelerometer a measurement of an acceleration vector in the orientation tracking device's.Type: ApplicationFiled: July 14, 2016Publication date: July 5, 2018Applicant: University of Cape TownInventor: Adam Marthinus Johannes van Niekerk
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Publication number: 20180184941Abstract: One embodiment of an apparatus for analysis of body composition and hydration status by detecting resistance of the human subject at zero and infinite frequency including a method for measuring indirectly extracellular water mass, intracellular water mass, lean body mass, and body fat mass; daily changes of extracellular water mass, intracellular water mass, lean body mass, and body fat mass; and acute changes of extracellular water mass and intracellular water mass; and for individualized calibration of these indirect measurements.Type: ApplicationFiled: February 27, 2018Publication date: July 5, 2018Inventor: Zsolt Peter Ori
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Publication number: 20180184942Abstract: Apparatus and method for imaging a patient in an MRI system. This includes a frame, and at least one assembly that includes an earpiece positioner connected to a reference position on the frame, a first lockable joint on the positioner; and an earpiece connected to a patient-proximal end of the positioner by a second joint, wherein the first earpiece is movably positioned to a selected pitch angle, a selected yaw angle, and a selected one of a plurality of distances relative to the reference position on the frame. The first lockable joint is configured to be tightened to yieldably hold the first earpiece at the selected pitch and yaw angles, and at the selected one of the plurality of distances, relative to the reference position. Optionally a second substantially similar earpiece and assembly are provided. The earpiece(s) optionally include audio transducer(s) and/or RF coil(s).Type: ApplicationFiled: February 27, 2018Publication date: July 5, 2018Inventor: Brandon J. Tramm
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Publication number: 20180184943Abstract: Detecting spatial location and rotation (pitch, roll and yaw) of an implantable programmable valve device having a direction of flow of fluid therethrough. A permanent-magnet rotor disk associated with the valve has magnets arranged in a ring. A single position within the ring represents a moveable reference marker position. Also included in the valve is a first fixed, stationary, non-moveable magnet disposed a predetermined distance relative to the moveable reference marker position. A magnetoresistive sensor array produces the as magnetic field pattern including a moveable reference marker corresponding to the moveable reference marker position in the ring and a first fixed reference marker corresponding to the first fixed, stationary, non-moveable magnet. An indicator device determines spatial location based only on the moveable reference marker and yaw based on the moveable reference marker relative to the first fixed reference marker.Type: ApplicationFiled: January 5, 2017Publication date: July 5, 2018Inventor: Thomas Boden, JR.
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Publication number: 20180184944Abstract: An implantable sensor configured to be inserted in an intramedullary canal can include a primary insert, a secondary insert, and an antenna. The primary insert can include a distal end, a proximal end opposite the distal end, and a central bore that can extend from an opening in the distal end towards the proximal end. A secondary insert can be receivable within the central bore through the opening. The secondary insert can include a body and a sensor module. The body can be removably engageable with an inside surface of the central bore. The sensor module can be disposable within the body and can be configured to produce a sensor signal as a function of a first sensed parameter indicative of infection. The antenna can be disposed in the central bore. The antenna can be configured to transmit a wireless signal as a function of the sensor signal.Type: ApplicationFiled: January 5, 2017Publication date: July 5, 2018Inventors: Hilbrandus H. Bodewes, Mohammed Imran Khan, Daniel László-Deli, Max Hoeboer, Lisa Abdel Alim-van den Berg, Siemon Van Opstal, Bonita Koperdraat, Bart Krijgsman, Jurrit Heerink
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Publication number: 20180184945Abstract: A method and device for detecting a worsening of the cardiopulmonary state of a patient treated by a respiratory assistance device comprising means for gathering and processing parameters which are representative of a first parameter that is representative of the patient's respiratory frequency over a first observation window, e.g. daily; a second parameter that is representative of the percentage of cycles that were initiated by the patient during a second observation window, e.g. daily; and a third parameter that is representative of the usage time of the device during a third observation window, e.g. daily.Type: ApplicationFiled: June 4, 2015Publication date: July 5, 2018Inventors: Jean-Christian BOREL, Nellie TALEUX-EYSSAUTIER, Nathalie ARNOL, Renaud TAMISIER, Jean Louis PÉPIN
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Publication number: 20180184946Abstract: A system and method for remotely monitoring an individual, in accordance with some embodiments of the invention. More particularly, one or more physiological functions and/or physical activities of the individual may be monitored. In order to monitor the individual, a range to, and/or a range rate (i.e., velocity) of, one or more points on one or more surfaces of the individual (e.g., skin, clothing, lips, etc.) may be determined over time. Based on the determinations of the range and/or range rate of the points on the surfaces of the individual, the one or more physiological functions and/or physical activities of the individual may be monitored. This may enable the physiological functions and/or physical activities to be monitored remotely from the individual without access or proximity to the individual.Type: ApplicationFiled: January 8, 2018Publication date: July 5, 2018Applicant: Digital Signal CorporationInventors: Richard Lee Sebastian, Kendall L. BELSLEY
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Publication number: 20180184947Abstract: An integrated goniometry system and method for use of the same are disclosed. In one embodiment of the goniometry system, an optical sensing instrument, a display, a processor, and memory are communicatively interconnected within a busing architecture in a housing. The optical sensing instrument monitors a stage, which is a virtual volumetric cubic area that is compatible with human exercise positions and movement. The display faces the stage and includes an interactive portal which provides prompts, including an exercise movement prompt providing instructions for a user on the stage to execute a set number of repetitions of an exercise movement, such as a bodyweight overhead squat. The optical sensing instrument senses body point data of the user during each exercise movement. Based on the sensed body point data, a mobility score, an activation score, a posture score, and a symmetry score may be calculated.Type: ApplicationFiled: January 2, 2018Publication date: July 5, 2018Inventors: Skylar George Richards, Andrew Menter, Mohammad Almoyyad, Anastasios Chrysanthopoulos, Randall Joseph Paulin, Nake A. Sekander, David Espenlaub
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Publication number: 20180184948Abstract: A system, method and apparatus for diagnosis and therapy. Preferably, the system, method and apparatus is provided for diagnosis and therapy of neurological and/or neuromuscular deficits by using a computational device. Optionally and preferably, the system, method and apparatus track one or more physical movements of the user, which are then analyzed to determine whether the user has one or more neurological and/or neuromuscular deficits. Additionally or alternatively, the system, method and apparatus induce the user to perform one or more physical movements, whether to diagnose such one or more neurological and/or neuromuscular deficits, to treat such one or more neurological and/or neuromuscular deficits, or a combination thereof.Type: ApplicationFiled: December 21, 2017Publication date: July 5, 2018Inventors: Tej TADI, Aurelien DA CAMPO, Frederic CONDOLO
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Publication number: 20180184949Abstract: A stretch sensor includes a first elastic insulating layer, a first elastic conductive layer, an elastic dielectric layer, a second elastic conductive layer and a second elastic insulating layer sequentially piled together thereon. The first and the second elastic insulating layers include the same elastic resin, and the first and the second elastic conductive layer include the same elastic resin and the same conductive material. The elastic dielectric layer includes the elastic resin and a dielectric material, in which the dielectric material comprises at least one of an Sr1-xCaxTiO3 compound, an Sr1-yBayTiO3 compound, and a BaTiO3 compound so as to make the dielectric constant of the dielectric material within 15.65-2087.3 F/m.Type: ApplicationFiled: December 29, 2017Publication date: July 5, 2018Inventors: Tzu-Hsuan Huang, Wei-Liang Liu
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Publication number: 20180184950Abstract: A system for testing a biological subject includes an imaging device and an imaging agent detectable by the imaging device, for detecting amount and location of a biomarker in the biological subject. The imaging agent includes a fluorescent microsphere and a targeting member attached to the fluorescent microsphere. A method of testing a biological subject using the system includes providing the imaging agent, applying the imaging agent to a testing location of a patient and imaging the imaging agent in the testing location by the imaging device, so as to detect the amount and locations of the imaging agent. A method of screening and diagnose a cancer that is accessible via cavity of a patient, includes performing a CD44 and total protein test, and if the result is positive, performing an imaging test.Type: ApplicationFiled: April 6, 2016Publication date: July 5, 2018Inventors: Robert C. Bohannon, Elizabeth Franzmann, Matthew H.J. Kim
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Publication number: 20180184951Abstract: Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration.Type: ApplicationFiled: February 23, 2018Publication date: July 5, 2018Inventors: Andrea Varsavsky, Xiaolong Li, Mike C. Liu, Yuxiang Zhong, Ning Yang
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Publication number: 20180184952Abstract: Disclosed are methods, apparatuses, etc. for calibrating glucose monitoring sensors and/or insulin delivery systems. In certain example embodiments, blood glucose reference samples may be correlated with sensor measurements with regard to a delay associated with the sensor measurements. In certain other example embodiments, a blood-glucose concentration in a patient may be determined based, at least in part, on one or more probability models, one or more functions for estimating blood-glucose concentrations, and/or blood glucose reference sample-sensor measurement pairs.Type: ApplicationFiled: February 28, 2018Publication date: July 5, 2018Inventors: Anirban Roy, Barry Keenan, Michael Kremliovsky
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Publication number: 20180184953Abstract: Sensors and methods for measurement of an analyte in a medium within a living animal are described. The sensor may include an inductive element that may receive power from an external device. The sensor may also include a charge storage device (CSD) and a memory. The sensor may perform analyte measurements initiated by the external device using power received from the external device and convey the analyte measurements to the external device using the inductive element. The sensor also may perform autonomous analyte measurements using the on board charge device's power and store the autonomous analyte measurements in the memory. The sensor may convey one or more stored analyte measurements to the external device using the inductive element using power received from the external device. The sensor may include a CSD-powered clock and a CSD-powered measurement scheduler that initiate the autonomous analyte measurements.Type: ApplicationFiled: February 26, 2018Publication date: July 5, 2018Applicant: Senseonics, IncorporatedInventors: Andrew DeHennis, Szymon Tankiewicz, Todd Whitehurst
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Publication number: 20180184954Abstract: Methods, devices, and systems are provided for correcting lag in measurements of analyte concentration level in interstitial fluid. The invention includes receiving a signal representative of sensor data from an analyte monitoring system related to an analyte level measured over time, computing rates of change of the sensor data for a time period of the sensor data, computing a rate distribution of the rates of change, transforming the rate distribution into a linear arrangement, determining a best-fit line for the transformed rate distribution, computing a slope of the best-fit line; and using the slope of the best-fit line as a representation of a variability of the analyte level to adjust an amount of lag correction applied to the sensor data. Numerous additional features are disclosed.Type: ApplicationFiled: March 2, 2018Publication date: July 5, 2018Applicant: Abbott Diabetes Care Inc.Inventor: Erwin Satrya Budiman
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Publication number: 20180184955Abstract: The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof.Type: ApplicationFiled: February 28, 2018Publication date: July 5, 2018Applicant: Abbott Point of Care Inc.Inventors: Gary Vandersleen, Pierre Emeric, Paul Wasserman, Narendra Soman, Graham Davis, Tian-Xian Zhao, Paul Glavina
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Publication number: 20180184956Abstract: Oxygen sensing luminescent dyes, polymers and sensors comprising these sensors and methods of using these sensors and systems are provided.Type: ApplicationFiled: December 4, 2017Publication date: July 5, 2018Inventors: Soya Gamsey, Natalie Wisniewski, Kristen Helton, William McMillan
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Publication number: 20180184957Abstract: A system for taking blood samples from a patient, including a peristaltic pump having a rotor with a moving surface and a fixed surface for lodging therebetween a flexible tube and a head member for attachment of a sample holder tube support member, and a blood sampling device including a needle holder having a tubular portion for supporting a hypodermic needle having a connection base, the needle holder including a conduit with an inlet and an outlet, where the inlet has the tubular portion, the sample holder tube support member, and the flexible tube having a first end in fluid communication with the needle holder and a second end in fluid communication with the support member.Type: ApplicationFiled: June 29, 2016Publication date: July 5, 2018Applicant: CLINICLAB S.L.Inventor: Ferran XALABARDER MIRAMANDA
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Publication number: 20180184958Abstract: Systems and methods are provided to measure reaction times and/or responses for head, eye, eyelid movements, and/or changes in pupil geometry. The system includes eyewear or headwear including one or more eye-tracking cameras for monitoring the position and geometry of at least one eye and its components of the user, one or more scene cameras for monitoring the user's surroundings, and one or more processors to determine reaction times. Optionally, the system may include one or more of a multi-axis accelerometer to monitor head movements, light sources to trigger visual evoked responses, and/or electronic inputs that may be used to indicate the time of occurrence of external reference events. Measured reaction times and other measurements may be monitored for use in a range of applications. Responses and reaction times may be measured continuously over extended periods, even over a lifetime to measure consequences of the aging process.Type: ApplicationFiled: February 15, 2018Publication date: July 5, 2018Inventors: Nelson G. PUBLICOVER, William C. TORCH
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Publication number: 20180184959Abstract: [Object] To provide an information processing device, a control method, and a program that can recognize an emotion of another user using sensing information of a user. [Solution] An information processing device including: an emotion recognition unit configured to recognize, on the basis of information concerning a user and information concerning another user having been sensed, an emotion of the other user; and a notification control unit configured to perform control such that the user is notified of information concerning the emotion of the other user having been recognized.Type: ApplicationFiled: January 21, 2016Publication date: July 5, 2018Inventor: RYO TAKAHASHI
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Publication number: 20180184960Abstract: A computer-implemented method of assessing a stress condition of a subject (106) includes receiving (302), as input, a heartbeat record (200) of the subject. The heartbeat record comprises a sequence of heartbeat data samples obtained over a time span which includes a pre-sleep period (208), a sleep period (209) having a sleep onset time (224) and a sleep conclusion time (226), and a post-sleep period (210). At least the sleep onset time and the sleep conclusion time are identified (304) within the heartbeat record. A knowledge base (124) is then accessed (306), which comprises data obtained via expert evaluation of a training set of subjects and which embodies a computational model of a relationship between stress condition and heart rate characteristics. Using information in the knowledge base, the computational model is applied (308) to compute at least one metric associated with the stress condition of the subject, and to generate an indication of stress condition based upon the metric.Type: ApplicationFiled: June 15, 2016Publication date: July 5, 2018Applicant: Medibio LimitedInventors: Matthew FLAX, Aaron WONG, Michael PLAYER, Todd JOLLY, Hans STAMPFER
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Publication number: 20180184961Abstract: A computer-implemented method of assessing a mental state of a subject (106) includes receiving (302), as input, a heartbeat record (200) of the subject. The heartbeat record comprises a sequence of heartbeat data samples obtained over a time span which includes a pre-sleep period (208), a sleep period (209) having a sleep onset time (224) and a sleep conclusion time (226), and a post-sleep period (210). At least the sleep onset time and the sleep conclusion time are identified (304) within the heartbeat record. A knowledge base (124) is then accessed (306), which comprises data obtained via expert evaluation of a training set of subjects and which embodies a computational model of a relationship between mental state and heart rate characteristics. Using information in the knowledge base, the computational model is applied (308) to compute at least one metric associated with the mental state of the subject, and to generate an indication of mental state based upon the metric.Type: ApplicationFiled: June 15, 2016Publication date: July 5, 2018Applicant: Medibio LimitedInventors: Matthew FLAX, Aaron WONG, Michael PLAYER, Todd JOLLY, Hans STAMPFER
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Publication number: 20180184962Abstract: Computer-implemented systems and methods are provided for determining indications of a mental state of a subject. A computing system may receive at least one electrophysiological signal from at least one pair of electrodes on a head of a subject. The system may store at least one threshold bio-electrical value, and compare a plurality of portions of the at least one electrophysiological signal with the stored value. The system may determine, based on the comparing, identities of portions of the at least one electrophysiological signal that surpass the stored at least one threshold bio-electrical value. The system may also determine the existence of a portion sequence among the portions of the at least one electrophysiological signal that surpass the stored at least one threshold bio-electrical value. And the system may output an indication of a mental state of the subject when it is determined that the portion sequence exists.Type: ApplicationFiled: June 23, 2016Publication date: July 5, 2018Applicant: BrainMarc Ltd.Inventor: Goded Shahaf
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Publication number: 20180184963Abstract: A system and methods for improving emotional well-being linked to physiological change in the human voice box by stimulating vagus nerve connected to motor and sensory functions in the voice box.Type: ApplicationFiled: May 8, 2016Publication date: July 5, 2018Applicant: Beyond Verbal Communication LtdInventor: Yoram LEVANON
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Publication number: 20180184964Abstract: Methods for diagnosing Autism and/or Autism Spectrum Disorder (ASD) of a subject include establishing baseline brain wave patterns of the subject by having the subject perform a series of task and measuring brain waves during the tasks using an EEG measurement device, applying a light stimulus or images to the subject's eyes and capturing eye movements and/or changes in facial expression in response to the light stimulus or images, and giving a neuropsychological and cognition battery of tasks to the subject to generate a provoked cognitive assessment of the subject. A processing device correlates the baseline brain wave patterns, eye movements and/or facial expressions, and provoked cognitive assessment of the subject to profile data indicative of Autism and/or ASD. The corresponding system may also include an auditory testing device that tests the subject's sensitivity to sound and records the subject's speech in response to verbal tasks.Type: ApplicationFiled: June 30, 2015Publication date: July 5, 2018Inventors: Adam J. SIMON, David M. Devilbiss
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Publication number: 20180184965Abstract: A urine handling system capsule for releasing an oil mixture in the lumen of a urine handling system, the capsule comprising a capsule wall defining a space filled with an oil mixture, wherein the oil mixture comprises 90-100% of an oil selected from the group consisting of silicone fluids and mineral oils or a mixture thereof, and having a viscosity of at most 600 cSt, and wherein the capsule wall is made of a water-soluble material. A urine measurement system comprising an oil mixture arranged in the luminal space of the measurement system. A method for inhibiting impairment of functionality and measurement accuracy in a urine measurement system comprising applying an oil mixture to the inner surfaces of the urine measurement system. Use of an oil mixture in treatment of luminal surfaces of a urine handling system.Type: ApplicationFiled: March 1, 2018Publication date: July 5, 2018Inventors: Mikael CHARLEZ, Mikael LOFGREN
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Publication number: 20180184966Abstract: A multi-axis measurement device for loading force and center of gravity is provided comprising a first loading plate, and comprising: a first slidable element and a first piezoelectric pressure sensing element. A second loading plate comprising: a second slidable element and a second piezoelectric pressure sensing element. A connecting plate, respectively connects to the first slidable element, the first piezoelectric pressure sensing element, the second slidable element, and the second piezoelectric pressure sensing element. A plurality of third piezoelectric pressure sensing elements connects to the first loading plate. The first piezoelectric pressure sensing element measures the changes in force of the X-axis direction, the second piezoelectric pressure sensor element sensing element measures the changes in force of the Y-axis direction, and the third piezoelectric pressure sensor element sensing elements measure the changes in force of the Z-axis direction.Type: ApplicationFiled: February 27, 2018Publication date: July 5, 2018Inventors: Lan-Yuen GUO, Chen-Wen YEN, Lih-Jiun LIAW, Jhen-Cyun CHENG
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Publication number: 20180184967Abstract: The present invention provides a gloss evaluation device, a gloss evaluation method, and a non-transitory computer readable recording medium storing gloss evaluation program capable of evaluating gloss of skin easily and highly accurately. In the gloss evaluation device of the present invention, a skin evaluation index calculation unit 5 calculates, as a skin evaluation index, a chroma difference between a portion in which it is easy for the gloss of the face of the subject to occur and a portion in which it is difficult for gloss to occur that are set as analysis ranges, and a luster and oiliness evaluation unit 6 evaluates luster and oiliness on the basis of the chroma difference.Type: ApplicationFiled: March 1, 2018Publication date: July 5, 2018Applicant: FUJIFILM CorporationInventor: Naoko YOSHIDA