Patents Issued in January 15, 2019
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Patent number: 10179183Abstract: An improved mobile apparatus for sterilizing surgical trays serves as a self-contained autoclave, allowing sterilization of the interior of the apparatus and its contents. A method of sterilization using the apparatus is presented as well. By means of a dedicated transfer and storage system, the apparatus, integrable with respect to a transfer cart and a lift device, may be moved easily between a location of sterilization, a storage area, and an operating room, and more than one such apparatus may be stacked vertically for storage to enhance storage efficiency.Type: GrantFiled: May 30, 2017Date of Patent: January 15, 2019Assignee: Progressive Sterilization, LLCInventors: Barry M. Snyder, Clarence J. Snyder, III, Michele Mauzerall, Maryellen Keenan
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Patent number: 10179184Abstract: A device for dispensing a fragrance includes a container which has at least one outlet opening and is used for receiving the fragrance. Associated to the container is an electric heating element for heating the fragrance and a temperature sensor for detecting the temperature of the fragrance. The electrical heating element is controlled by a controller as a function of the temperature detected by the temperature sensor.Type: GrantFiled: November 25, 2014Date of Patent: January 15, 2019Assignee: AUDI AGInventors: Karsten Belz, Georg Techel, Michael Holzer
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Patent number: 10179185Abstract: A process for producing water-absorbing polymer particles is provided, comprising a) a polymerization step in which an aqueous monomer solution comprising at least one ethylenically unsaturated monomer M which bears acid groups and may have been at least partly neutralized and at least one crosslinker is polymerized to obtain an aqueous polymer gel; b) a pelletization step in which the aqueous polymer gel having a solids content of 35 to 70% by weight and a temperature of 75 to 125° C. is forced from a high-pressure zone through a die plate into a low-pressure zone and pellets are obtained, the pressure differential between the high-pressure zone and the low-pressure zone being 4 to less than 14 bar and the orifice ratio of the die plate being 30 to 80%; c) a drying step in which the pellets are dried to a moisture content of less than 10% by weight; d) a grinding step and a classifying step to obtain water-absorbing polymer particles; and e) surface crosslinking of the water-absorbing polymer particles.Type: GrantFiled: May 7, 2015Date of Patent: January 15, 2019Assignee: BASF SEInventors: Markus Braun, Monica Haag, Stephan Deuerlein, Volker Klock, Roland Krauss
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Patent number: 10179186Abstract: Single layer and multi-layer anti-microbial wound care fabrics, gloves, sleeves, anklets, socks, finger cots, masks, and similar wound care articles are disclosed.Type: GrantFiled: June 27, 2013Date of Patent: January 15, 2019Assignee: Ansell LimitedInventors: Jeffrey Moreland, Roger Eugene Huckfeldt, Dion Ross, Eric Thompson, Jamie Ashworth, Michael Zedalis, Anthony B. Lopez
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Patent number: 10179187Abstract: The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin.Type: GrantFiled: December 5, 2013Date of Patent: January 15, 2019Assignee: Regents of the University of MinnesotaInventors: Jafar Golzarian, Lihui Weng
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Patent number: 10179188Abstract: Embolic materials, suspensions, kits and related methods useful for embolization are disclosed. An embolic material can comprise a resorbable microsphere including cross-linked gelatin as its primary ingredient and having a substantially spherical shape with a diameter of about 50 micrometers to about 1,500 micrometers, inclusive. The microsphere can optionally include one or both of a marker or an active agent. The microsphere can be cross-linked, such as with glutaraldehyde or formaldehyde, which can affect the microsphere's in vivo degradation profile and ability to withstand a sterilization process at certain temperatures. In an embodiment, the microspheres can resorb during an in vivo time period of between about 24 hours and about 15 weeks, inclusive. An embolization suspension can include a plurality of resorbable microspheres and a liquid carrier, and the suspension can be disposed in a syringe, vial or other applicator for administration to a patient.Type: GrantFiled: July 13, 2018Date of Patent: January 15, 2019Assignee: TELEFLEX INNOVATIONS S.À.R.L.Inventors: Stephen Penegor, Jason Isenburg, James Murto
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Patent number: 10179189Abstract: Methods to produce thermoforms from P4HB homopolymer and blends thereof have been developed. These thermoforms are produced from films and sheets including P4HB, wherein the intrinsic viscosity of the P4HB is less than 3.5 dl/g, but greater than 0.35 dl/g, and the thermoforms are produced at a temperature equal to or greater than the softening point of P4HB, and more preferably at a temperature higher than the melting point of P4HB. A preferred embodiment includes a P4HB thermoform wherein a film or sheet including a P4HB polymer is thermoformed at a temperature between its melting point and 150° C. In a particularly preferred embodiment the thermoform is a laminate made from a P4HB film and a P4HB mesh.Type: GrantFiled: May 19, 2017Date of Patent: January 15, 2019Assignee: Tepha, Inc.Inventors: Matthew Bernasconi, Dennis Connelly, Said Rizk, David P. Martin, Simon F. Williams
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Patent number: 10179190Abstract: Methods of treating tissue of a patient, e.g., tissue of an organ such that the bladder, are described. The methods may comprise inserting a medical device within the bladder; and injecting a composition to separate a first layer of tissue from a second layer of tissue. The composition may comprise at least one polysaccharide compound having a concentration ranging from approximately 0.05% to approximately 25% by weight, with respect to the total weight of the composition. The composition may at least partially separate the first layer of tissue from the second layer of tissue. At least one of the first layer of tissue or the second layer of tissue may be a detrusor muscle tissue.Type: GrantFiled: May 27, 2016Date of Patent: January 15, 2019Assignee: Boston Scientific Scimed, Inc.Inventors: Sandra Nagale, David Shreeve, Mark Boden, Jonathan Zoll, Timothy Harrah, Steven Kangas, Kasyap Seethamraju, Deanna Cavallaro, Martin Phelan
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Patent number: 10179191Abstract: Compositions and methods for repair of tissue defects are disclosed. The compositions are prepared by entangling high molecular weight polycaprolactone polymer molecules with a polysaccharide such as hyaluronic acid by a dual solvent emulsion process to produce a porous flexible matrix which supports cell and tissue growth in vivo and ex vivo.Type: GrantFiled: October 9, 2014Date of Patent: January 15, 2019Assignee: Isto Technologies II, LLCInventors: Mitchell S. Seyedin, Anthony J. Ward
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Patent number: 10179192Abstract: The present invention relates to a peripheral nerve-specific hydrogel material, which is deliverable in a minimally invasive fashion, sustains the growth of neurons, and speeds recovery following surgical reconstruction.Type: GrantFiled: July 12, 2017Date of Patent: January 15, 2019Assignees: UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, CORNELL UNIVERSITYInventors: Bryan Nicklaus Brown, Jonathan Cheetham
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Patent number: 10179193Abstract: Provided are tri-component matrices having collagen, hyaluronan, and chondroitin sulfate. Also provided are processes for producing a tri-component matrix. Additionally, provided are processes for providing cells capable of producing cartilage to a bone or cartilage defects.Type: GrantFiled: January 16, 2018Date of Patent: January 15, 2019Assignee: SCRIPPS HEALTHInventors: Darryl D. D'Lima, Tsaiwei Olee, Clifford W. Colwell
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Patent number: 10179194Abstract: The present invention relates to the use of peptides, peptoids and/or peptidomimetics capable of self-assembling and forming a (nanofibrous) hydrogel in biofabrication. The present invention further relates to methods for preparing hydrogels and to methods for preparing continuous fibres and to methods for obtaining multi-cellular constructs with defined, precise geometrics. The present invention further relates to various uses of such hydrogels for obtaining mini-hydrogel arrays and 3D organoid structures or 3D macromolecular biological constructs.Type: GrantFiled: December 1, 2014Date of Patent: January 15, 2019Assignee: Agency for Science, Technology and ResearchInventors: Charlotte Hauser, Yihua Loo
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Patent number: 10179195Abstract: The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers.Type: GrantFiled: February 17, 2014Date of Patent: January 15, 2019Assignee: Massachusetts Institue of TechnologyInventors: Christopher J. Bettinger, Joost P. Bruggeman, Lino da Silva Ferreira, Jeffrey M. Karp, Robert S. Langer, Christiaan Nijst, Andreas Zumbuehl, Jason Burdick, Sonia J. Kim
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Patent number: 10179196Abstract: Wound dressings, systems, and methods are presented for treating a wound on a patient's limb, such as a venous leg ulcer. The dressings, systems, and methods involve creating airflow within the dressing to vaporize and remove liquid. The airflow may begin when the dressing becomes saturated. The dressings may be used to provide compression and reduced pressure to the wound. Other systems, methods, and dressings are presented herein.Type: GrantFiled: August 5, 2016Date of Patent: January 15, 2019Assignee: KCI Licensing, Inc.Inventors: Benjamin Andrew Pratt, Christopher Brian Locke
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Patent number: 10179197Abstract: A catheter pump comprising a pump head for insertion into the aorta. The pump head includes: a rotor having propellers that can be displaced from a folded insertion position in which the pump head can be inserted into the aorta, to an unfolded operating position in which the rotor can be set in rotation, and a cage surrounding the propellers. The cage comprises a distal, proximal sheath and filaments running between sheaths. The sheaths are moved towards one another at or before the unfolding of the propellers in a manner that the regions of the filaments lying between the sheaths expand radially outward, to form a space surrounding the unfolded propellers. At least some or all of the filaments are configured so as to each have at least one main section that engages one sheath and splits into at least two minor sections in the direction toward the other sheath.Type: GrantFiled: November 21, 2016Date of Patent: January 15, 2019Assignee: CardioBridge GmbHInventors: Siegfried Kaiser, Klaus Epple
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Patent number: 10179198Abstract: Methods include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.Type: GrantFiled: August 18, 2015Date of Patent: January 15, 2019Assignee: MEDTRONIC, INC.Inventors: Martin Gerber, John Burnes, Suping Lyu, VenKatesh R. Manda, Bryant Pudil
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Patent number: 10179199Abstract: A medical apparatus for extracorporeal blood treatment and a method for determining blood parameter value have been provided. The medical apparatus has a control unit (9) configured for taking from a storage memory (10) a plurality of blood parameter value measures each made through the sensors (8) provided on the bloodline set of each of a machines plurality at different patient treatment sessions; all the blood parameter values relate to the same patient; receiving at least a corresponding laboratory measured valise of the same blood parameter relating to the same patient and a laboratory measurement time; determining a correction factor function of a difference between a measured value made though the sensor and a laboratory measured value; obtaining an actual value of said blood parameter by varying at least the last measure made through the sensor by means of the correcting factor.Type: GrantFiled: March 12, 2015Date of Patent: January 15, 2019Assignee: Gambro Lundia ABInventor: Bernard Bene
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Patent number: 10179200Abstract: A disposable cassette and system for dialysis are disclosed. An example disposable cassette includes a rigid portion, a fluid source inlet configured to be placed in fluid communication with a fluid source, and a fluid pumping receptacle placed in fluid communication with the fluid source inlet. The fluid pumping receptacle is configured to operate with a fluid pump actuator to pump fluid from the fluid source. The example disposable cassette also includes a dampening chamber formed as part of the rigid portion and in fluid communication with the fluid pumping receptacle. The dampening chamber is sized and arranged to reduce pressure fluctuations in the fluid delivered from the fluid pumping receptacle. The example disposable cassette further includes an outlet in fluid communication with the dampening chamber. The outlet provides dialysis fluid for a dialysis treatment.Type: GrantFiled: November 10, 2017Date of Patent: January 15, 2019Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Robert W. Childers, David S. Brown, Ramesh Wariar, Sujatha Karoor, Shahid Din, Leo Martis, Cody Buchmann, Paul Soltys
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Patent number: 10179201Abstract: Systems and sensor clip assemblies for optically monitoring blood flowing through a blood chamber are provided. A sensor clip assembly includes emitters and photodetectors positioned on opposing arms, a signal conditioning circuit for conditioning raw analog signals generated by the photodetectors while the sensor clip assembly is fastened to a blood chamber, and an analog-to-digital converter for converting the conditioned analog signals to raw digital data. The sensor clip assembly may output the raw digital data to an external device and receive synchronized control signals from the external device, or the sensor clip assembly may include a microcontroller for performing calculations on the raw digital data and providing synchronized control signals internally. Parameters of blood flowing through the blood chamber such as hematocrit, oxygen saturation, and change in blood volume may be calculated from the raw digital data derived from the raw analog signals generated by the photodetectors.Type: GrantFiled: August 25, 2017Date of Patent: January 15, 2019Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Louis L. Barrett, David W. Peterson, Matthew A. Stowell, Perry N. Law
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Patent number: 10179202Abstract: Systems and methods for cleaning body cavities are presented. Described embodiments include systems for cleaning feces from the lower GI tract. Also provided are systems for steering such a cleaning system, also useful for steering an endoscope or other tool inserted into a body.Type: GrantFiled: January 11, 2011Date of Patent: January 15, 2019Assignee: Motus GI Medical Technologies Ltd.Inventors: Boris Shtul, Alexey Morochovsky, Alexander Banzger, Noam Hassidov
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Patent number: 10179203Abstract: An intravenous (IV) site and medical tubing protection device which diminishes the inadvertent, non-purposeful dislodging of an IV catheter, as fluids are being delivered to a patient via a medicine dispensing unit. It employs a self-contained retractable spring spool unit consisting of medicinal tubing 13, a spring-loaded, retractable spool 8, an IV Luer 5, a lubricating ring port 9, a swiveling fluid junction 10, bolus valve 11, and a plastic shell container 7. Medicinal tubing 13 enters the plastic shell container 7 through a lubricating ring port 9 and winds around the retractable spool 8. The tubing attaches to a swiveling fluid junction 10, which permits a constant flow of fluid through the patient line, despite any extending or retracting of the tubing. A subsequent patient line attaches to the swiveling fluid junction 10 at its other end and then to an IV luer 5 that extends beyond the plastic shell 7. An IV catheter can then be attached to the luer 5.Type: GrantFiled: March 30, 2016Date of Patent: January 15, 2019Inventor: Kathy McArthur Huslage
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Patent number: 10179204Abstract: A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.Type: GrantFiled: August 12, 2016Date of Patent: January 15, 2019Assignee: West Pharma. Services IL, Ltd.Inventor: Oz Cabiri
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Patent number: 10179205Abstract: A safety needle system includes a safety mechanism for a needle assembly, such as a Huber needle. A main body has a channel having a proximal end to encompass tubing and a distal end for positioning proximate a needle. The main body further has a first hinge mechanism and a first latching mechanism. A movable cover has needle receptacle, a second hinge mechanism connected with the first hinge mechanism of the main body, and a biasing member for pivoting movable cover about the first and second hinge mechanisms relative to the main body. The movable cover has a second latching mechanism to latch with the first latching mechanism in a closed position, in which the safety mechanism can be undocked from the needle and slid away from the needle along the tubing. The movable cover has a release mechanism to allow pivoting of the movable cover about the hinge mechanisms such that the needle receptacle of the movable cover at least partially receives the needle of the needle assembly in an open, locked position.Type: GrantFiled: February 4, 2016Date of Patent: January 15, 2019Inventor: Terrell L. Friedrich
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Patent number: 10179206Abstract: A medicament delivery device is presented having a housing, and a medicament container holder arranged movable in a longitudinal direction in relation to the housing. The medicament container holder is arranged to accommodate a medicament container, is arranged as a multi-chamber container having a medicament and a diluent in different chambers, a plunger rod operably arranged to act on the medicament container, a retaining element capable of releasably retaining the plunger rod to the housing, actuation force elements capable of, upon activation, moving the medicament container holder in relation to the housing such that the plunger rod acts on the medicament container for mixing the medicament and the diluent.Type: GrantFiled: April 10, 2015Date of Patent: January 15, 2019Assignee: SHL MEDICAL AGInventors: Antonio Bendek, Lucio Giambattista
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Patent number: 10179207Abstract: A supplemental device for attachment to an injection device. A supplemental device for attachment to an injection device, the supplemental device comprising: a housing; an electromechanical switch arrangement, the electromechanical switch arrangement comprising: a main body; and a switching member, the switching member having a protrusion arranged to protrude from the main body so as to contact a surface of the injection device while the supplemental device is attached to the injection device; and a biasing member configured to bias at least a part of the main body of the electromechanical switch arrangement against the injection device while the supplemental device is attached to the injection device.Type: GrantFiled: July 30, 2013Date of Patent: January 15, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventor: Martin Haupt
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Patent number: 10179208Abstract: A dispensing mechanism for administering a dosage of a medicament includes dosage setting means (7) for setting the dosage of a medicament to be administered; expelling means (15) for expelling a medicament from a medicament container; and coupling means (21) operatively coupled with the dosage setting means (7) and the expelling means (15), wherein the coupling means (21) is arranged to convert displacement of the dosage setting means (7) into a displacement of the expelling means (15) in a first direction, wherein the expelling means (15) includes a ratchet means (18a, 18b), and wherein the mechanism includes a first and a second independently moveable resisting pawl (14a, 14b) means facing a common side of the ratchet means (18), the first and the second resisting pawl means (14a, 14b) being configured to engage with the ratchet means (18a, 18b) and resist displacement of the expelling means (15) in a second direction opposite to said first direction.Type: GrantFiled: March 14, 2014Date of Patent: January 15, 2019Assignee: Norton Healthcare LimitedInventors: Neil Cammish, Mark Horlock
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Patent number: 10179209Abstract: A needle covering system for a needle of a syringe. A boot of the system defines a contaminant-proof pocket for the needle. A sealing ring portion of the boot forms a seal with a support portion of the syringe. A body of the boot is collapsible to allow movement of a needle pierceable end portion of the boot toward the sealing ring portion for a tip of the needle to pass through the boot end portion for an injection. A securement collar of the system presses the sealing ring against the support portion of the syringe and is a remnant portion of a protective shell.Type: GrantFiled: February 6, 2015Date of Patent: January 15, 2019Assignee: Eli Lilly and CompanyInventors: Jesse Arnold Fourt, Jeremy Christopher Koehler
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Patent number: 10179210Abstract: A medical needle safety device includes a needle mount for supporting the needle and a needle shielding sleeve surrounding a supported needle coaxially with the mount, for sliding from a needle shielding position towards a non-shielding position. The mount (30) provides a sliding surface and a resiliently flexible finger is provided on the sleeve, the finger being resiliently deformed outwardly as the sleeve moves towards a non-shielding position, to urge the sleeve back to a shielding position. A control member is disposed within the sleeve and the inner surface of the finger has a camming surface with a transition profile between the inner surface and canning surface. On initial rearward movement of the sleeve, the control member interacts with the camming surface of the finger to flex the finger outwardly and store energy therein.Type: GrantFiled: December 19, 2013Date of Patent: January 15, 2019Assignee: TIP-TOP.COM LTD.Inventor: Barry Peter Liversidge
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Patent number: 10179211Abstract: The invention relates to a safety needle device, for a medical instrument, to insert a needle into a patient's body to a determined insertion depth. The safety needle device, in two variants with a fixed insertion depth and with an insertion depth adjustment, comprises a hub, a needle, a protecting shield, longitudinal resilient means, transverse resilient means, a housing, and is provided with different technical means configured to cooperate with each other in order to perform different functions of the device. The safety needle device enables to control a state of use of the device, wherein the device is a disposable one and it ensures its user a protection against an accidental or intentional prick of the needle before and after the due use of the device for the purpose for which it is intended.Type: GrantFiled: October 28, 2013Date of Patent: January 15, 2019Assignee: HTL-STREFA SPOLKA AKCYJNAInventors: Marcin Rozwadowski, Vincent Leskowich
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Patent number: 10179212Abstract: An injection device for expelling a dose of drug from a held cartridge (600) is described. A needle shield (350, 380) is axially movable relative to a base (200, 220, 230) between a proximal collapsed position and a distal extended position. A needle shield lock comprises a deflectable lock element (392) operable to prevent the needle shield (350, 380) from being moved towards the proximal collapsed position. A lock activator (402) associated with a plunger (310, 400) exerts an activation force on the deflectable lock element when the plunger assumes a final position. A biasing means (403) is arranged to act between the lock activator (402) and the deflectable lock element (392), the biasing means (403) being configured to resiliency transfer the activation force from the lock activator (402) to the deflectable lock element (392) to enable the needle shield (350, 380) to become locked in the distal extended position but only when the plunger (310, 400) assumes the final position.Type: GrantFiled: June 26, 2015Date of Patent: January 15, 2019Assignee: Novo Nordisk A/SInventors: Mads Schenstroem Stefansen, Soeren Kjellerup Hansen, Bastian Gaardsvig Kjeldsen
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Patent number: 10179213Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.Type: GrantFiled: May 27, 2016Date of Patent: January 15, 2019Assignee: VITAL SIGNS, INC.Inventors: Christopher Varga, Jason Anthony Mohr, Megan Danielle Friedlander
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Patent number: 10179214Abstract: The invention relates to a device for injection of a product into an injection site. The device including a needle shield for protection of a needle prior to use of the device; a housing; and a deshielder for removing the needle shield from the device. The deshielder is coupled to the needle shield and mounted on the housing in a separable manner. The deshielder may include tamper evidence features that are activated by the removal of at least one part of said deshielder. At least one part of the deshielder may be configured to be removed from the housing by exerting a force equal or less to 30 N.Type: GrantFiled: August 21, 2014Date of Patent: January 15, 2019Assignee: Becton Dickinson FranceInventors: David Llewellyn-Hyde, Vernon Rich, Herve Abry, Frederic Perot, Jerome Blanc, Lionel Maritan
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Patent number: 10179215Abstract: Apparatus and methods are described for use with a vaporizer that vaporizes at least one active ingredient of a plant material. In response to receiving a first input to the vaporizer, the plant material is heated, in a first heating step. An indication of the temperature of the plant material is detected, and, in response to detecting an indication that the temperature of the plant material is at a first temperature, the first heating step is terminated, by withholding causing further temperature increase of the plant material. The first temperature is less than 95 percent of the vaporization temperature of the active ingredient. Subsequently, a second input is received at the vaporizer. In response thereto, the plant material is heated to the vaporization temperature, in a second heating step. Other applications are also described.Type: GrantFiled: March 19, 2015Date of Patent: January 15, 2019Assignee: Altria Client Services LLCInventor: Yossef Raichman
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Patent number: 10179216Abstract: A nasal delivery device comprising: a housing (15); a nosepiece (17) for fitting to a nasal cavity of a subject; a mouthpiece (19) through which the subject in use exhales; and a substance supply unit (21) including an actuation member (23) which extends from one end of the housing and is manually actuated to deliver substance to the nasal cavity of the subject; wherein the housing includes a grip section (27) which is disposed at the one end of the housing from which the actuation member extends, said grip section comprising a first, distal part (28) including at least one projecting grip element (29) by which the subject grips the housing in actuating the actuation member, and a second, proximal part (31) providing a recess (33) in which fingers of the subject are located, said recess promoting proper orientation of the delivery device in a hand of the subject.Type: GrantFiled: February 25, 2013Date of Patent: January 15, 2019Assignee: OptiNose ASInventors: Per Gisle Djupesland, Kate Dudgeon, Joseph Gordon, Mark Guarraia, Michael Leclerc, Ramy A Mahmoud
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Patent number: 10179217Abstract: A monitoring system for multiple medical ventilators is provided. In one aspect, the monitoring system includes a memory that includes instructions, and a processor. The processor is configured to execute the instructions to receive data for a plurality of medical ventilators, and identify a configuration for each of the plurality of medical ventilators from the received data for the plurality of medical ventilators. The processor is also configured to execute the instructions to associate each patient with a respective one of the plurality of medical ventilators, determine an identification and status for each patient associated with one of the plurality of medical ventilators, and provide, for display, information indicative of the configuration of each of the plurality of medical ventilators and indicative of the identification and status of each patient associated with one of the plurality of medical ventilators. Methods and machine-readable media are also provided.Type: GrantFiled: March 28, 2016Date of Patent: January 15, 2019Assignee: Vyaire Medical Capital LLCInventors: Tom Steinhauer, Willis Lam, Terry Blansfield, Stephen J. Birch, Leonard Mulkowsky, Clifton Pait, Mark Rogers
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Patent number: 10179218Abstract: A continuous positive airway pressure (CPAP) apparatus for respiratory assistance of a pattern is disclosed. There is a blower having an output connectible to a ventilation mask wearable by the patient. A first pressure sensor measures blower pressure at the output of the blower, and a second pressure sensor that is connectible to the ventilation mask measures mask pressure therein. A pressure controller is connected to the first pressure sensor and the second pressure sensor, and a patient inspiratory phase and a patient expiratory phase is be detectable by the pressure controller to regulate therapeutic pressure at the patient mask, based upon pressure differentials between the mask pressure and the blower pressure.Type: GrantFiled: March 2, 2012Date of Patent: January 15, 2019Assignee: BREATHE TECHNOLOGIES, INC.Inventors: Samir S. Ahmad, Leonardo Alberto Baloa Welzien, Enrico Brambilla
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Patent number: 10179219Abstract: Intubation devices, systems, and methods in which the risk of leakage of nasopharyngeal secretions, esophageal reflux, and blood is reduced, or eliminated, by means of a backflow pressure gradient that is independent of PEEP. Contemplated configurations include (a) a flexible tube for the controlled delivery of air and other gases to the lungs, (b) distal and proximal inflatable seals that can close the annular space surrounding the tube, (c) means to inflate the seals, and (d) means to deliver gas under pressure to the annular chamber in between the two seals. Further configurations further comprise a processor and sensors, and methods are provided for automated backflow of contaminated fluids.Type: GrantFiled: April 13, 2017Date of Patent: January 15, 2019Inventor: Daniel Marcos Chapiro
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Patent number: 10179220Abstract: The invention involves masks and systems for providing respiratory treatments to various animals including horses, mules and ponies. The masks are low in cost due to simple designs, a very low thickness requiring less material and the systems include the masks of the invention.Type: GrantFiled: July 22, 2016Date of Patent: January 15, 2019Inventor: Rebecca G. Canaday
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Patent number: 10179221Abstract: A device 10 for providing a breathing gas stream, which contains a therapeutically active substance, for the mechanical respiration and/or mechanical breathing assistance of a patient, wherein the device 10 has at least one first line 21, through which a first gas stream 31 flows during the operation of the device, and wherein the device 10 has at least one second line 22, wherein the first line 21 and the second line 22 have a common section 13, and wherein the first line 21 and the second line 22 are connected to one another by a water vapor-permeable membrane 24 in the area of the common flow section 13, the present invention provides for a second gas stream 32 to flow through the second line 22 during the operation of the device.Type: GrantFiled: January 30, 2014Date of Patent: January 15, 2019Assignee: DRÄGERWERK AG & CO. KGAAInventor: Norbert Wruck
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Patent number: 10179222Abstract: A system for delivering a therapeutic amount of nitric oxide can include a reservoir assembly, a gas supply, and a delivery conduit including a first cartridge, wherein the first cartridge can include a surface-activated material saturated with an aqueous solution of a reducing agent. In certain embodiments, the reservoir includes a restrictor.Type: GrantFiled: November 18, 2014Date of Patent: January 15, 2019Assignee: VERO BIOTECH LLCInventors: David H. Fine, Gregory Vasquez, Bryan Johnson, Ryan Denton, Lucas G. Gamero
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Patent number: 10179223Abstract: Apparatus for inducing sleep comprising: a. a display for providing a subject with a light stimulus; b. a base unit on which said display is mounted such that the display is selectively positionable, in use, into a field of view of a subject; c. input means for recording an active input provided by the subject in response to the stimulus; d. processing means for processing said active input to determine a characteristic of said active input; and e. a base unit housing one or more of said means, wherein the apparatus is capable of sequentially providing the subject with a plurality of stimuli, each next stimulus being based on a characteristic determined from the active input made in response to a previous stimulus, and wherein a position and/or brightness and/or a color and/or a shape of the next stimulus on the display and/or a time interval between stimuli is based on the characteristic of the active input provided in response to a previous stimulus.Type: GrantFiled: September 16, 2014Date of Patent: January 15, 2019Assignee: Braintrain2020 LimitedInventor: Richard Mills
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Patent number: 10179224Abstract: An enhanced flexibility neurovascular catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the side wall includes an outer jacket surrounding a helical coil, and the outer jacket is formed from a plurality of tubular segments positioned coaxially about the coil. A proximal one of the tubular segments has a durometer of at least about 60D, and a distal one of the tubular segments has a durometer of no more than about 35D. An axially extending filament within the side wall extends at least about the most distal 10 cm of the length of the catheter. The axially extending filament serves as a tension support and resists elongation of the catheter wall under tension, such as when the catheter is being proximally retracted through tortuous vasculature.Type: GrantFiled: February 27, 2017Date of Patent: January 15, 2019Assignee: Incept, LLCInventors: Yi Yang, Fred Khosravi, Lisa M. Young
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Patent number: 10179225Abstract: A guidewire introducable into a bodily lumen having an obstruction therein is provided. An introducer needle is advanced through tissue and into the bodily lumen. A guidewire is advanced through the introducer and into the lumen. The guidewire is advanced further through the lumen until an atraumatic distal tip of the guidewire encounters an obstruction the distal tip cannot pass in a straight forward manner. The distal tip is pressed against the obstruction such that a flexible segment proximal of the distal tip forms a loop distal of the distal tip. The guidewire is advanced further through the lumen such that the loop of the flexible segment is pushed past the obstruction and the distal tip is pulled distally past the obstruction. A greater diameter guidewire extension can be coupled to the back end of the guidewire, providing function as a larger diameter guidewire.Type: GrantFiled: February 26, 2016Date of Patent: January 15, 2019Inventors: Thomas A. Sos, Mitchell Tatum
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Patent number: 10179226Abstract: A syringe which has an intended pressure limit. The syringe includes a syringe body, and a pressure-limiting mechanism is disposed inside the syringe body. The pressure-limiting mechanism may comprise a valve body which is spring biased in the syringe body. In one embodiment, the pressure-limiting mechanism is provided in the form the valve assembly having a valve seal which moves into sealing engagement with an internal wall of a valve bore in the syringe housing once the intended pressure limit is reached. In another embodiment, the pressure-limiting mechanism is provided in the form of the valve assembly having a valve seat which moves into sealing or plugged engagement with a valve plug once the intended pressure limit is reached. Regardless of the exact configuration, preferably the syringe is simple, reliable, easy to assembly, and easy to sterilize given its low number of parts.Type: GrantFiled: June 30, 2016Date of Patent: January 15, 2019Assignee: ATRION MEDICAL PRODUCTS, INC.Inventors: Rowland W. Kanner, Brian A. Roberts
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Patent number: 10179227Abstract: A dilation device comprises an elongate shaft, an inflatable balloon, and a resilient tube. The inflatable balloon is disposed along the shaft. The resilient tube is also disposed along the shaft and is positioned to encompass at least part of the inflatable balloon. The resilient tube is configured to impose an inwardly directed resilient bias on at least a portion of the exterior of the inflatable balloon. At least part of the resilient tube is secured to one or both of the elongate shaft or the inflatable balloon.Type: GrantFiled: March 12, 2013Date of Patent: January 15, 2019Assignee: Acclarent, Inc.Inventors: Sivette Lam, Ketan P. Muni
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Patent number: 10179228Abstract: Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.Type: GrantFiled: August 30, 2016Date of Patent: January 15, 2019Assignee: Rani Therapeutics, LLCInventor: Mir Imran
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Patent number: 10179229Abstract: According to some embodiments, a skin treatment assembly comprises a tip comprising a proximal end and a distal end, a container configured to secure to the tip along the proximal end of the tip, wherein the container is configured to contain a liquid, and a porous member configured to extend at least partially within an interior of the container such that it contact a liquid contained within the container, wherein the porous member is configured to extend at least partially within an interior of the tip and is configured to facilitate the transfer of liquid from the container to the distal end of the tip.Type: GrantFiled: April 26, 2017Date of Patent: January 15, 2019Assignee: Edge Systems LLCInventors: Roger Ignon, Ed F. Nicolas
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Patent number: 10179230Abstract: An access port for subcutaneous implantation is disclosed. Such an access port may comprise a body for capturing a septum for repeatedly inserting a needle therethrough into a cavity defined within the body. Further, the access port may include at least one feature structured and configured for identification of the access port subsequent to subcutaneous implantation. Methods of identifying a subcutaneously implanted access port are also disclosed. For example, a subcutaneously implanted access port may be provided and at least one feature of the subcutaneously implanted access port may be perceived. Further, the subcutaneously implanted access port may be identified in response to perceiving the at least one feature. In one embodiment, an identification feature is included on an insert that is incorporated into the access port so as to be visible after implantation via x-ray imaging technology.Type: GrantFiled: January 26, 2018Date of Patent: January 15, 2019Assignee: Bard Peripheral Vascular, Inc.Inventors: Kelly B. Powers, William R. Barron
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Patent number: 10179231Abstract: A medical connector for use in a fluid pathway includes a housing configured to permit fluid flow between a first medical device and a second device or location. The medical connector includes a valve member configured to be positioned at least partially within the housing. The valve member is configured to receive the first medical device. The valve member can be moved into a second state. The connector can be adapted for use with a catheter assembly.Type: GrantFiled: May 8, 2015Date of Patent: January 15, 2019Assignee: ICU Medical, Inc.Inventors: David Nelson, Joseph K Walker
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Patent number: 10179232Abstract: A catheter including a tube with a coupling assembly at one end. The coupling assembly has an interior volume within which a ball is capture between a seat and a retainer. When fluid flows through the catheter in a first directed the fluid flows around the ball and exits through a port. When fluid starts to back-flow in a second direction the ball seals against the seat preventing flow in the second direction.Type: GrantFiled: July 15, 2015Date of Patent: January 15, 2019Inventor: Bruce T. Huici