Abstract: Provided are a fixing module and a motion assistance apparatus including the fixing module including a first side frame including a first central portion on one side of a user, a first front extending portion configured to extend from the first central portion along a front side of the user, and a first rear extending portion configured to extend from the first central portion along a rear side of the user, and a second side frame including a second central portion on another side of the user, a second front extending portion configured to extend from the second central portion along the front side of the user, and a second rear extending portion.

Abstract: A cap for preventing hair loss has a crown with protrusions extending from the concave surface of the crown. When the cap is placed on a user's skull at least one of the protrusions is aligned with a suture in the skull. Rubbing on the exterior of the crown at the locations of the protrusion will abrade excess bone growth or thickening on top of the suture thereby assuring circulation to the scalp to support hair growth.

Abstract: Pneumatic and therapeutic compression systems are disclosed including treatment protocols that may be used with such systems. A pneumatic compression system may include a source and sink of a pressurizing fluid. The pressurizing fluid may be sourced to a number of valves, each valve controllable by a control device including a computing device. The computing device may control each valve separately to allow any one or more of the valves to connect to the fluid source or the fluid sink. The computing device may include one or more therapeutic protocols that may direct one, two, or more valves to switch between fluid sourcing and fluid sinking, substantially simultaneously or in a sequence. A therapeutic compression system may include the pneumatic system in fluid communication with an inflation sleeve composed of multiple cells. Each cell may be inflated or deflated by a valve according to the therapeutic protocol.

Abstract: In a method of treating erectile dysfunction in a patient, a predetermined course of external counter-pulsation treatment is applied to a lower body portion of the patient. After the predetermined course of external counter-pulsation treatment is applied, a predetermined course of low intensity shockwave treatment is applied to a penile area of the patient. After the course of low intensity shockwave treatment, a predetermined course of carboxy therapy is applied to a corpora cavernosa of the patient.

Abstract: A gum massaging device includes a sheet member closely attachable to a gum, a gum-condition sensor disposed on the sheet member, and a massaging element disposed on the sheet member at a position corresponding to a position at which the gum-condition sensor is disposed, the massaging element operating in accordance with a detection result from the gum-condition sensor. The gum-condition sensor detects, for example, a color tone of a portion of the gum adjacent to the gum-condition sensor. The massaging element provides, for example, a pinching massage to a portion of the gum adjacent to the massaging element.

Abstract: A cap assembly for removable attachment to a non-mechanized masturbation device is provided. The cap assembly comprises at least one moveable extension member, and at least one actuator adapted to move the extension member. The actuator may include a motor. The actuator is adapted to move the extension member in one or more selected directions, such that the extension member can contact an elastomeric gel provided as part of the non-mechanized masturbation device, and move a portion of the elastomeric gel to impart sensation to a user.

Abstract: A device for use by a female that includes an external housing, an internal skeleton, and a motorized portion. The external housing is configured to conform to the user's shape and form. The internal skeleton may be deformed by the user as desired. The internal skeleton includes shape-memory properties so that after deformation, the device retains the shape desired by the user. The motorized portion is secured within the external housing so that desired portions of the device receive the majority of the stimulation provided by the motorized portion.

Abstract: The invention provides a sensing control method and apparatus, and a vibration massage apparatus. The method comprises: arranging a sensor which senses a trajectory of an external object, and controlling the change of output based on the direction of the trajectory. With the invention, a desirable control effect can be obtained based on the sensed direction of the trajectory of the external object without accurate positioning of the sensor. Not only the convenience of the sensing operation can be improved significantly, but also the control accuracy can be improved; meanwhile, the invention can be well applied to any device for control using several input control signals or variable input control signals for control, thus having a wide range of application and significantly optimizing user experience.

Abstract: A liner for containing a soaking solution in use with a foot spa features two bodies of plastic which are joined at an interface therebetween so as to form two, individual layers. An air conduit is formed between the two layers so as to provide a passageway for pressurized air, which is supplied by an air discharge apparatus, across walls of the liner and into the soaking solution. The inner layer has openings such that the air guided through the air conduit can be released into an inside volume of the liner where the soaking solution is containable. Furthermore, the outer layer is imperforate from a location thereon at which a starting end of the air conduit is disposed to a free end of the layers so as to isolate the inside volume of the liner from the soaking basin.

Abstract: A system for packaging an item with an identifier comprises an identifier adder, a labeler, and a packager. The identifier adder adds one or more types of silica-based tags to an item, wherein each type of silica-based tag has a first signature readable using an optical spectroscopic reader. A label is generated based at least in part on reading the one or more types of silica-based tags of the item using the optical spectroscopic reader. The label includes goods info. The packager includes the label on a package, and wherein the packager includes the item in the package.

Abstract: A capping device for disinfection of a medical container is provided. The capping device includes a top portion having an inner surface, a bottom portion having an inner surface and an opening, and a connector. The connector couples the top portion of the capping device to the bottom portion thereof in a manner which permits movement of the top portion between a fully-seated position on the bottom portion of the capping device to form a hollow defined by the inner surface of the top portion of the capping device and the inner surface of the bottom portion thereof, and a position apart from the opening to permit ingress to the vial. The capping device further includes a disinfecting absorbent material disposed inside the hollow and extending through the opening in the inner surface of the bottom portion.

Abstract: A container for pharmaceutical preparations includes a base body. The container has at least one first holding element embodied such that it can work together with a corresponding second holding element of a holding device for the container in order to hold the base body securely on the holding device.

Abstract: An adaptor for coupling with a medical container filled with a number N of doses of a product including a gripping member for securing the adaptor to the medical container. The gripping member has at least one needle access port intended to face the outer surface of the septum of the medical container. The adaptor also includes a marking-device coupled to the needle access port, for designating to a user a not yet pierced area of said outer surface, for completing the next of the N successive piercings.

Abstract: A needle-free adaptor for removing liquid from a vial comprises a cannula adapted to piece a septum of a vial, a plurality of legs surrounding the cannula to secure the adaptor to the vial when the cannula has pieced the septum, an elastomeric membrane having a normally closed pinhole orifice, and a conforming surface having an orifice connected to the cannula. The elastomeric membrane has a stable convex shape and is adapted to receive a nozzle of a needle-free device. Pressed against the elastomeric membrane, the nozzle deflects the elastomeric membrane from the convex shape to an unstable or pseudo-stable inverted position against the conforming surface. Buckling of the elastomeric membrane opens the pinhole orifice and enables fluid communication between the vial and the nozzle by interfacing the pinhole orifice with the orifice on the conforming surface.

Abstract: The present invention relates to medical devices containing time-release drug substance, and more particularly, to medical tubing, catheters, stents, cables (including fiber optic cables), pills, capsules, sheaths, threads, clamps, sutures, and endotracheal devices. The invention also generally relates to a method for extruding multiple laminated flow streams using microlayer coextrusion to create these various time-release drug delivery products.

Abstract: Provided is a die roll for manufacturing softgels, a softgel, and methods for producing a softgel. The die roll includes a die roll surface and a pocket defined therein. The pocket includes a floor, an interior sidewall surface, a chamfer, and an exterior sidewall surface. The floor is recessed relative to the die roll surface and the interior sidewall surface is connected to the floor and extends above the die roll surface to the chamfer. The pocket also includes a landing surface that is elevated from the die role surface and connects the chamfer to the exterior sidewall surface of the pocket. The landing surface includes a taper (such that the landing surface tapers inwardly towards the pocket floor) and a radius (such that the landing surface is not flat). Also provided is a softgel having a trailing edge thickness that is at least about 40% the thickness of the softgel wall thickness.

Abstract: The invention provides an elastomeric expandable container having a first opening adapted to enable the introduction of a comestible fluid under pressure to inflate the same, and a second opening provided in a nipple-like projection extending from said container and adapted for nursing babies, said second opening being closed by valve means, and said valve means being opened and closed by the natural nursing actions of the baby to enable fluid to flow under pressure of the inflated container through said nipple and out of the opening thereof.

Abstract: In one aspect of the invention features nursing bottle. The nursing bottle includes a container for holding a liquid and having a rim defining an open end and a nipple assembly secured to the container at the open end. The nipple assembly includes a flexible nipple extending away from the container and defining an interior nipple volume, a vent bulb disposed within the interior nipple volume and defining an interior bulb volume, a tube extending into the container to a distal end disposed in a closed end of the container, and a vent manifold. The vent manifold defines a first aperture providing fluid communication between the container and the interior nipple volume, a second aperture providing fluid communication between the tube and the interior bulb volume, and a vent conduit providing fluid communication between the interior bulb volume and atmosphere.

Abstract: A pacifier (1) is provided which comprises a nipple (2) and a shield (3) made of an elastic material. The shield (3) comprises two stable mechanical states: one in which the shield (3) acts as a shield and another in which the shield (3) acts as a nipple cover. The shield (3) is transformable from one stable mechanical state to another upon an impact to the shield (3).

Abstract: Addition-fragmentation agents having the following functional groups: 1) a labile addition-fragmentation group that can cleave and reform to relieve strain, 2) at least one high refractive index group, and 3) at least one ethylenically unsaturated, polymerizable group are described.

Abstract: The invention relates to a curable dental retraction composition comprising alginate and a solvent, with the proviso that essentially no crosslinker in an amount effective to start setting of the curable dental retraction composition is present. The invention also relates to a container containing said composition and to a kit comprising two parts, wherein the first part comprises the curable dental retraction composition of the present invention and the second part comprises a crosslinker being able to start setting of the dental retraction composition.

Abstract: Radically polymerizable dental material which contains as initiator for the radical polymerization a combination of a thiourea derivative and a bisacyldialkylgermanium compound.

Abstract: Disclosed are oil-in-water (O/W) emulsions comprising (a) an aqueous dispersion of particles of at least one latex chosen from an acrylate latex, a polyurethane latex, or a silicone latex, and (b) an oil phase, wherein the aqueous dispersion of particles of at least one latex is present in the O/W emulsion in an amount sufficient to stabilize the O/W emulsion. The disclosure also relates to hair styling and/or shaping compositions comprising the O/W emulsions, methods of making the compositions, and methods of styling and/or shaping the hair.

Abstract: Emulsifiers are provided that are able to stabilize water-in-oil emulsions. The emulsifiers are homogenous and have a relatively low melting point (e.g., soft pastes, gels or liquids at room temperature), enabling their use in cold-process methods/formulations which reduce energy consumption, manufacturing costs, as well as allow the use thermolabile active ingredients. The water-in-oil emulsifiers may comprise: (a) polyglycerol fatty acid esters consisting of saturated and unsaturated fatty acid esters of polyglycerol; (b) polyhydroxystearic acid copolymers consisting of copolymers of hydroxystearic acid with saturated and unsaturated fatty acids; and (c) hydroxystearic acid. Methods and uses relating to the emulsifiers are also described, for example in cosmetic and pharmaceutical compositions.

Abstract: The present invention relates to an oral care composition with a high water content which has improved robustness towards microbial challenge. The oral care composition includes compositions comprising from 0.125 wt % to 0.75 wt % of a water soluble source of stannous ions, wherein the composition comprises at least 50 wt % water and wherein the source of stannous ions is selected from the group consisting of stannous chloride, stannous pyrophosphate, stannous formate, stannous acetate, stannous gluconate, stannous lactate, stannous tartrate, stannous oxalate, stannous malonate, stannous citrate, stannous ethylene glyoxide, and mixtures thereof.

Abstract: The invention provides a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl? having antibacterial and antiperspirant properties, together with personal care compositions comprising the complex, and methods of making and using these complexes and compositions.

Abstract: The present invention relates to a composition for dyeing keratin fibres, in particular keratin fibres such as the hair, comprising: a) at least one oxidation base 3-(2,5-diaminophenyl)-1-propanol acid salts thereof or solvates thereof such as hydrates; b) at least one heterocyclic oxidation base; c) at least one coupler; d) optionally at least one fatty substance; e) optionally at least one basifying agent; and f) optionally at least one chemical oxidizing agent. The invention also relates to a process for dyeing keratin fibres such as the hair using the composition of the invention, and to a multi-compartment device for using the composition of the invention.

Abstract: The present invention provides a cosmetic composition containing (A) a powder composed of one or more kinds of the N-medium-chain-acyl basic amino acid powder represented by the following formula (I), (B) an inorganic powder, and (C) an oil material: wherein R is a saturated or unsaturated straight hydrocarbon group having 5-9 carbon atoms, and m is an integer of 1-4.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.

Abstract: The present invention relates to a composition that acts prior to the action of a tooth whitening composition or tooth whitening patch, the composition containing an oral cavity stimulation alleviating component able to reduce stimulation by the tooth whitening composition or patch. The present invention also relates to a tooth whitening kit whereby oral cavity stimulation is alleviated. The composition that acts prior to the action of a tooth whitening composition or patch of the present invention provides an outstanding tooth whitening effect while alleviating pain by mitigating intra-oral stimulation brought about by the rapid action of a tooth whitening component due to a tooth whitening component active agent.

Abstract: A method for shaping keratin fibers including providing a crosslinking composition, wherein the crosslinking composition includes ethylene carbonate, arabinose, a photocatalyst being a hydroxy-substituted aromatic compound, and a cosmetically acceptable carrier; applying the crosslinking composition to keratin fibers; and mechanically shaping the keratin fibers with an appliance at a temperature of from 80° C. to 180° C. while exposing the crosslinking composition to electromagnetic radiation having a wavelength of from 300 nm to 750 nm.

Abstract: An oral composition for reducing dentinal hypersensitivity according to the present invention comprises a phosphorylcholine-containing polymer as an active ingredient. A general consumer can use the oral composition routinely in various forms. The oral composition is brought into contact with an oral cavity of a user to reduce the dentinal hypersensitivity.

Abstract: The present invention relates to a cosmetic composition comprising a dispersion of acrylic polymer particles, a semi-crystalline polymer and an organic solvent. The compositions of the present invention may optionally contain at least one colorant. The invention also relates to a method for making up and/or enhancing the appearance of a keratinous substrate, in particular lashes, by applying these compositions to the keratinous substrate.

Abstract: The present invention relates to a photocurable composition for coating a nail or an artificial nail, including: a component (A): an acrylate oligomer; a component (B): a methacrylate monomer; and a component (C): a photopolymerization initiator. The present invention provides a photocurable composition for coating a nail or an artificial nail, which has a small amount of heat generation during curing by light irradiation.

Abstract: Provided are compositions and methods that are useful for personal care compositions. The compositions comprise (a) a cationic polymer comprising polymerized units derived from (i) 30 to 80 weight % of cationic monomers, (ii) 10 to 65 weight % of (meth)acrylamide monomers, and (iii) 0 to 30 weight % of polar non-ionic derivatives of acrylic monomers, and (b) silicone. Also provided are methods of treating hair with such compositions.

Abstract: The present invention relates to an organopolysiloxane graft polymer including an organopolysiloxane segment as a main chain thereof and an unsaturated monomer-derived copolymer segment containing a repeating unit derived from an unsaturated monomer containing a carboxylic acid or a carboxylic acid salt as a side chain thereof, in which a content of the organopolysiloxane segment in the organopolysiloxane graft polymer is 35 to 59% by mass, a content of the repeating unit derived from the unsaturated monomer containing a carboxylic acid or a carboxylic acid salt in the organopolysiloxane graft polymer is 4 to 17% by mass, and a content of a repeating unit derived from an unsaturated monomer whose homopolymer has a glass transition point of not lower than 150° C.

Abstract: Methods and compositions for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ a botanical extract of Justicia ventricosa, Archidendron clypearia, Abrus fruticulosus, or combinations thereof and a cosmetically acceptable vehicle.

Abstract: A method comprising topically applying to facial skin a composition comprising an aqueous, alcoholic, or aqueous-alcoholic extract from Nymphoides peltatum.

Abstract: Injectable depot compositions, comprising a biocompatible polymer which is a polymer or copolymer based on lactic acid and/or lactic acid plus glycolic acid having a monomer ratio of lactic to glycolic acid in the range from 48:52 to 100:0, a water-miscible solvent having a dipole moment of about 3.7-4.5 D and a dielectric constant of between 30 and 50, and a drug, were found suitable for forming in-situ biodegradable implants which can evoke therapeutic drug plasma levels from the first day and for at least 14 days.

Abstract: Disclosed is a preparation for transnasal application, which has improved fluidability. Specifically disclosed is a preparation for transnasal application, which comprises at least a complex comprising a fluidability-improving component comprising a first crystalline cellulose (A) having specified powder properties, tricalcium phosphate (B) having specified powder properties, and a second crystalline cellulose (C) having specified powder properties or a starch (D) having specified powder properties, and physiologically active substance.

Abstract: Described herein are methods and devices for the long term treatment of ophthalmic disorders. Also disclosed are encapsulated cell therapy (ECT) devices that secrete a biologically active molecule and methods for using the same for the treatment of various kinds of ophthalmic disorders, including retinitis pigmentosa, geographic atrophy (dry age-related macular degeneration), glaucoma and/or macular telangiectasia.

Abstract: Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions.

Abstract: A method of making an oral soluble film, containing at least one active agent, includes providing a well of a predetermined size; depositing a film forming composition in the well; depositing an active agent composition in the well, the active agent composition being different than the film forming composition, the film forming composition and the active agent composition forming an admixture in the well; and drying the admixture in the well. Alternatively, the method includes providing a well of a predetermined size; depositing a film forming composition including at least one active agent in the well, the film forming composition having a viscosity below 2000 centipoise; and drying the film forming composition in the well.

Abstract: The present disclosure provides a device for self-preparation of a gastroretentive dosage form being capable of transitioning between a collapsed configuration and an expanded configuration, the device comprising an assembly unit including: a compartment configured for accommodating the gastroretentive dosage form in the expanded configuration; and a mechanical system configured for, upon operation of an actuation mechanism: (a) transitioning said gastroretentive dosage form into the collapsed configuration; and (b) locking said collapsed gastroretentive dosage form into the collapsed configuration; wherein the device is configured for being portable.

Abstract: Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, and absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant.

Abstract: What is described is a method for treating a fibrotic disease by administering a pharmaceutical composition comprising a drug carrier, which comprises a lipid and a retinoid, and a double-stranded nucleic acid molecule, which comprises an antisense sequence to mRNA encoding human hsp47.

Abstract: The present document describes a compressible delivery formulation for transmucosal delivery of at least one compound which includes a micronized powder base; and a desiccated liposome formulation comprising at least one liposome containing at least one compound, process of making the same and process for making dosage forms from the formulation.

Abstract: A stable dry powder composition for inhalation includes acetylsalicylic acid in particles having a mass median aerodynamic diameter (MMAD) in a range of about 1 ?m to about 5 ?m. The dry powder composition may contain a pharmaceutically acceptable excipient, such as a stearate, in an amount ranging from about 0.04% (w/w) to about 0.06% (w/w), or from about 0.4% (w/w) to about 0.6% (w/w), of the composition.

Abstract: The invention provides compositions and devices for altering biological field effects and methods for their use in therapeutic and agricultural applications. In particular, the invention provides compositions including one or more elemental metals coated with one or more non-conducting or semi-conducting materials and methods for their application to animals (including humans) and/or plants.

Abstract: The present invention relates to a continuous process for preparing microspheres and microspheres prepared thereby, and in particular, a process for preparing microspheres comprising steps of injecting a first emulsion and a second emulsion at the same time to form microspheres instantaneously, applying high pressure to the microspheres formed, and injecting the microspheres into an agitator, wherein the steps can be carried out continuously, and microspheres prepared thereby. When microspheres are prepared using the method of the present invention, scale variables, which have been the biggest disadvantage in existing preparation methods of microspheres, can be significantly reduced, drug encapsulation efficiency can be improved, and small and uniform particles can be obtained.