Abstract: A method for implementing a dynamic three-dimensional lung map view for navigating a probe inside a patient's lungs includes loading a navigation plan into a navigation system, the navigation plan including a planned pathway shown in a 3D model generated from a plurality of CT images, inserting the probe into a patient's airways, registering a sensed location of the probe with the planned pathway, selecting a target in the navigation plan, presenting a view of the 3D model showing the planned pathway and indicating the sensed location of the probe, navigating the probe through the airways of the patient's lungs toward the target, iteratively adjusting the presented view of the 3D model showing the planned pathway based on the sensed location of the probe, and updating the presented view by removing at least a part of an object forming part of the 3D model.

Abstract: Methods, systems and devices for pre-operatively planned shoulder surgery guides and implants. Pre-operative planning methods for designing glenoid implants and prostheses, particularly with patient-specific augmentation, based on considerations of multiple factors affecting the outcome of shoulder surgery. Methods of using surgery guides and implants, including adaptive glenoid implants, in patients undergoing shoulder surgery.

Abstract: The present disclosure is directed to orthopedic implants and methods of rapid manufacturing orthopedic implants using in vivo data specific to an orthopedic implant or orthopedic trial. Specifically, the instant disclosure utilizes permanent orthopedic implants and orthopedic trials (collectively, “implants”) outfitted with kinematic sensors to provide feedback regarding the kinematics of the trial or implant to discern which implant is preferable, and thereafter rapid manufacturing the implant.

Abstract: A system and method for tracking an object within a surgical field are described. A system may include a mesh of cameras distributed around the surgical field, the mesh of cameras including, for example at least three cameras. Cameras in the mesh of cameras may be in known positions or orientations relative to the surgical field or may be mobile with position or orientation to be determined by the system. The system may include a computing system communicatively coupled to the mesh of cameras, the computing system including a processor and a memory device. The computing system may be used to generate tracking data for a tracked object from images or image data taken by one or more cameras of the mesh of cameras.

Abstract: Various embodiments provide a cardiac mapping method including: generating an activation map of a heart based on electrocardiogram (ECG) data of a heart and a three-dimensional (3D) heart model; performing an electrophysiology (EP) procedure to determine a first pacing location; pacing the heart at the first pacing location using an EP catheter; determining whether the pacing at the first pacing location generates a desired cardiac response; displaying guidance information related to a second pacing location on one or both of the activation map and the internal surface map, when the first pacing location is determined not to generate the desired cardiac response; moving the pacing catheter to the second pacing location, based on the guidance information; and pacing the heart at the second pacing location.

Abstract: The present invention relates to an image processing device and method, a surgical system, and a surgical member with which a position and an orientation of the surgical member for surgery of a subject can be easily grasped. The present invention acquires a microscopic image (201) obtained by photographing the surgical member (121) inserted to the subject with a surgical microscope (112), estimates the relative posture of the surgical member in the subject on the basis of the acquired microscopic image (201), and outputs posture information (222, 223, 224) associated with the posture that has been estimated. The present invention can be applied to ophthalmic surgery, in which an intraocular endoscope or surgical tool is observed with a surgical microscope, for example.

Abstract: A method performed by a computing system comprises receiving, from a fluoroscopic imager, having a first set of parameters, first fluoroscopic image data of a first fiducial marker within a surgical coordinate space. The method comprises receiving a configuration of the first fiducial marker within the surgical coordinate space. The method comprises determining a second set of parameters of the fluoroscopic imager in the surgical coordinate space based on the first flouroscopic image data and the configuration of the first fiducial marker. In some embodiments, determining the second set of parameters comprises developing a calibrated model of the fiducial marker in the surgical coordinate space from the first fluoroscopic image data and the configuration of the first fiducial marker.

Abstract: Devices, Systems, and Methods for determining the shape of a surgical implant and navigating the surgical implant during surgery are described. The shape of the surgical implant may be determined during surgery and a graphical representation of the surgical implant accurately depicting its shape are displayed and overlaid on graphical depiction of a target anatomy of a patient. The surgical implant may include a tracker recognizable by one or more cameras associated with the navigation system.

Abstract: An apparatus for performing dental surgery includes a central processing unit that controls automated operation of the apparatus and a display that renders an image of a target tooth requiring surgical intervention. The image of a target tooth being created from an image file received from the central processing unit. An input device receives surgical instructions from a user for providing the surgical intervention. The instructions are provided to the central processing unit for process. The surgical instructions include visual indications on the image of a target tooth that is to be treated. A robotic arm that includes an end effector is in communication with the central processing unit. The central processing unit controls the robotic arm to remove a region of the target tooth. The system also simultaneously mills the final tooth restoration in a separate milling chamber.

Abstract: A surgical instrument holder includes a carriage and a drive coupler. The carriage is configured for movable engagement to a surgical robotic arm. The drive coupler includes an outer member and a first gear rotatably disposed therein. The outer member extends from the carriage and defines a lateral slot configured for lateral receipt of a surgical instrument. The first gear defines a lateral slot and is rotatable within the outer member to a first position, in which the lateral slot of the first gear is in alignment with the lateral slot of the outer member such that a surgical instrument is receivable within the drive coupler through the lateral slots of the outer member and the first gear.

Abstract: Some embodiments are directed to a surgical master-slave robot for use in minimally (or reduced) invasive surgery on a subject. The robot includes an instrument manipulator for mounting of a surgical instrument, and a linkage system for moveably suspending the instrument manipulator. A first linkage component is configured for guiding a first suspension to move along a first movement trajectory. A second linkage component is configured for guiding a second suspension point to move along a second movement trajectory. The first movement trajectory and the second movement trajectory differ and are selected to provide a combined translational and rotational movement of the instrument manipulator which moves the instrument manipulator along a predefined trajectory from a surgical position to a standby position. The robot may provide a stable removal of the instrument manipulator during a surgery as well as sufficient surgeon's workspace after the removal of the instrument manipulator.

Abstract: Disclosed embodiments provide a biopsy tool and methodologies for obtain biopsies and/or a tool and methodology that may be used to add material to a subject's tissue.

Abstract: A system and method of variable velocity control of a surgical instrument in a computer-assisted medical device includes a surgical instrument having an end effector located at a distal end of the instrument, an actuator, and one or more drive mechanisms for coupling force or torque from the actuator to the end effector. To perform an operation with the instrument, the computer-assisted medical device is configured to set a velocity set point of the actuator to an initial velocity and monitor force or torque applied by the actuator. When the applied force or torque is above a first force or torque limit it is determined whether a continue condition for the operation is satisfied. When the continue condition is satisfied the operation is paused and when the continue condition is not satisfied it is determined whether forced firing of the actuator should take place.

Abstract: A pocket and drape system which provides one or more sterile fields, as well as the methodology for employing said pocket and drape system is provided. The pocket and drape includes a base drape material having an upper edge, a lower edge, a first side edge, and a second side edge to define a perimeter, where the base drape material also includes an inner surface and an outer surface. A first row of pockets and a second row of pockets are configured on the inner surface of the base drape material. In addition, a flap covers a portion of the inner surface of the base drape material, where the flap has a first surface and an opposing second surface, wherein the flap maintains at least one sterile field.

Abstract: The present invention relates to an adaptor of a laser for use in vision correction surgery that forms a laser beam non-irradiated region, of which an upper portion is coaxially aligned with an object lens of the laser, and a lower portion is coaxially aligned with a cornea of a patient, in order to set a position of the cornea of the patient with respect to the object lens of the laser.

Abstract: A bio-sensor strip adapted to be located between an object and a body part. The bio-sensor strip comprises one or more of bio-sensors (819, 919) disposed on at least one first polymer film (825), wherein the bio-sensors (819, 919) measure parameters at a location between the object (216, 316, 916) and the body part (932).

Abstract: A surgical clip applier includes a counter assembly including a counting wheel with a plurality of actuation features, a locking spring assembly, a driver, and a pin assembly. The counting wheel includes indicia visible through the handle assembly. The locking spring assembly is positioned within the counting wheel and is configured to prohibit multidirectional rotation of the counting wheel. The driver includes a grasping protrusion and a positioning protrusion. The driver translates between a proximal position and a distal position, wherein the grasping protrusion engages the plurality of actuation features to rotate the counting wheel to change the indicia. The pin assembly is configured to engage with the positioning protrusion of the driver, wherein during transitioning of the driver from the proximal position to the distal position, the positioning protrusion engages the stationary pin to pivot the driver, whereby the driver disengages from the plurality of actuation features.

Abstract: An endoscopic treatment tool, includes an elongated member having a distal end and a proximal end; a braid disposed between the distal end and the proximal end of the elongated member; a distal indicator disposed on the elongated member between a distal end and a proximal end of the braid, the distal indicator extending along a longitudinal axis of the elongated member; a proximal indicator disposed between the distal end and the proximal end of the braid on the elongated member at a more proximal side of the elongated member than the distal indicator, the proximal indicator extending along the longitudinal axis; and a pre-curved shape portion formed in a curved shape, wherein each of the distal indicator and the proximal indicator has a width less than half of an outer circumferential surface of the elongated member in a circumferential direction of the elongated member, respectively.

Abstract: The present invention relates to a head immobilization system for immobilizing a patient's head in a supine position of the patient, the system comprising: a support rail structure adapted to be coupled to a patient rest and extending at least on both lateral sides of the patient's head, a mask frame adapted to be coupled to at least one deformable upper mask sheet, wherein the mask frame is releasably connected to the support rail structure via a first interface section and a second interface section, with at least two pins protruding from the first interface section in a first direction, and at least two pin-receptions provided at the second interface section, wherein each one of the pin-receptions receives one of the pins, and a catch-mechanism for each pin-reception and each corresponding pin, which allows the pin to be pushed further into the pin-reception in the first direction, but which interlocks in case of an attempted withdrawal of the pin from the pin-reception in a second, opposite direction.

Abstract: A method of creating a dental implant drill-guide is provided, comprising the steps of using mucosal impression data of an edentulous maxillary or mandibular arch having a plurality of orthodontic screws inserted into the osseous tissue thereof and which extend through the gingival mucosa, along with image data of the arch to determine dental implant position data for the insertion of one or more dental implants into the edentulous maxillary or mandibular arch relative to the positions of the plurality of orthodontic screws. It is then possible to create a dental implant drill-guide to guide the drilling of dental-implant cavities in the edentulous maxillary or mandibular arch, and subsequently create a dental implant drill-guide from the dental implant drill-guide parameter data, the dental implant drill-guide having a plurality of orthodontic screw-seats which are engagable with the said plurality of orthodontic screws.

Abstract: A dental retractor comprises an elongated body having a first axis, a second axis and a third axis, each being orthogonal to each other. The first axis extends longitudinally from a proximal end to a distal end. The first axis and the second axis define a first plane and a width of the elongated body. The first axis and the third axis define a second plane and a thickness of the elongated body. The elongated body includes a blade extending from the distal end and lying substantially in the first plane; and a wing extending from the blade and lying at an angle relative to the first plane.

Abstract: A powder chamber, especially for or of a dental powder jet apparatus, including at least one conductive region, which is electrically conductive, where the at least one conductive region includes a contact surface, which is formed within the powder chamber.

Abstract: A powder chamber, in particular for powder polishing devices, including a casing and two functional sectors, whereby the two functional sectors are arranged to be opposite to each other, and whereby at least one functional sector is designed to provide an opening for a working medium such as air or a mixture of powder and air, and whereby the two functional sectors are designed to allow the powder chamber to be locked. The two functional sectors are preferably arranged along an axis and are rotationally symmetric.

Abstract: A thin-form mouthguard can be formed from a U-shape planar sheet. The sheet can be made of expanded-polytetrafluoroethylene and have a thickness between 0.02 inches and 0.25 inches. The sheet can also include instructions for modification of the mouthguard printed thereon. A method for preparing a mouthguard is also provided.

Abstract: A method includes forming a plastic orthodontic aligner having a plurality of cavities shaped to receive at least portions of a plurality of teeth of a patient. A first segment of the plastic orthodontic aligner corresponds to a first subset of the plurality of cavities for moving a first subset of the plurality of teeth of the patient. A second segment of the plastic orthodontic aligner corresponds to a second subset of the plurality of cavities. The method further includes removing a first portion of the plastic orthodontic aligner between the first and second segments of the plastic orthodontic aligner to form a connector to minimize force transmission between the first and second segments. The connector is configured to be disposed along one or more additional teeth to span a gap between the first and second segments without exerting a clinically significant force on the one or more additional teeth.

Abstract: A method and system for bone tissue regeneration in association with a predetermined dental bone structure obtains a computerized tomography scan of a dental bone structure on which to regenerate bone tissue. A three-dimensional model digitally represents the dental bone structure. A treatment plan corresponding to said three-dimensional model and a design order permit forming an occlusive barrier for covering the portion of the dental bone structure whereupon to regenerate bone tissue. An occlusive barrier from a biocompatible material and an osteoconductive material form flesh and regenerated bone tissue via osteoconduction. The occlusive barrier includes irrigation channels for permitting flushing of said interior volume and may be formed of pieces printed for forming a volume to regenerate bone tissue. The occlusive barrier may be subjected to a heat treatment for alleviating molecular stress and increasing occlusive barrier ductility and strength.

Abstract: A drill bit and method for normalizing bone is provided. The drill bit has a non-round drill bit core that is adapted to cut hard bone and to not cut soft bone. The drill bit has a cutting edge which may be positioned within a compression zone of the non-round drill bit core. The rotational speed of the drill bit and the profile of the drill bit core are tuned so that hard bone recovers into a cutting zone defined by the cutting edge while soft bone remains outside of the cutting zone. The insertion torque of the drill bit can be measured to determine when the normalization is adequate.

Abstract: A tool for 3D adjustment of a muscle position used at the adjustment of a jaw position is provided with a first member attached in a position corresponding to left and right molar regions, including a plurality of convex parts and a second member attached to a position opposing at least the first member, wherein the first member has a surface facing the second member provided with a plurality of convex parts, the convex parts having distal ends capable of sliding on an upper surface of the second member, and the second member has a surface facing at least the first member, the surface being a substantially flat surface. By using the articulator for 3D adjustment of a muscle position, the occlusal position is caused to correspond to the centric occlusal position with good accuracy, making it possible to produce a prosthetic appliance.

Abstract: An integrated dental porcelain system for making dental prostheses and restorations is provided. The system includes three universal major components: a) opaque porcelain composition; b) pressable dentin ingot; and c) veneering porcelain composition that can be used interchangeably for making restorations. Techniques for making the prostheses and restorations include porcelain fused-to-metal (PFM), press-to-metal (PTM), and either pressed and/or machined all-ceramic methods. The system uses both a hand-layering of veneering porcelain (PFM technique) and a hot-pressing process (PTM and all-ceramic technique) to fabricate the prostheses and restorations.

Abstract: The straw comprises a tube (11) and a gas-permeable liquid-tight stopper (12), which stopper is disposed in the tube in the neighborhood of one end (16), which tube and which stopper are configured for the stopper to be able to slide in the tube towards the other end (17), said tube being transparent or translucent, said stopper comprising an identifier component (13) configured to emit, when it is illuminated with ultraviolet light, light of which the spectrum comprises at least one peak having a crest of predetermined wavelength in visible light, whereas when it is illuminated by visible light said identifier component does not emit said light of which the spectrum comprises said peak.

Abstract: An introducer used to insert a urinary incontinence device into a vagina. The introducer includes a housing including a vaginal insertion tube at a proximal end of the housing and a storage section at a distal end of the housing. The storage section is shaped and dimensioned for storage of the urinary incontinence device prior to insertion and the vaginal insertion tube is shaped and dimensioned for the passage of the urinary incontinence device therethrough. The dimensions of the storage section are such that the urinary incontinence device contained therein is in its deployed non-compressed state allowing the urinary incontinence device to be stored in its non-compressed state prior to use. The introducer also includes a plunger which travels within the housing.

Abstract: A non-invasive device against urinary incontinence is described, which is adapted to be applied to the external part of a human penis and which is so shaped as to operationally encircle the penis by compression, the penis internally including a urethral duct in a lower position and two cavernous bodies in lateral positions, the device including a first part adapted to operationally exert an even compression force on the upper part of the penis, and a second part adapted to operationally exert direct compression forces on both cavernous bodies and indirect compression forces on the urethral duct, induced by the direct compression forces exerted on both cavernous bodies, so as to achieve a stable lateral compression for closing the urethral duct.

Abstract: A subcutaneous sling for neck lift surgery. The sling comprises a sling body, shaped to fit in a submental triangle of a patient undergoing neck lift surgery, comprising a narrow anterior edge for anchoring near the chin of the patient. The sling comprises two lateral sling extensions, each coupled to a respective side edge of two sides of the sling body, each projecting away from the center of the sling body in a posterior lateral orientation of between 45 and 90 degrees from the anterior-posterior axis, and curved slightly towards the narrow anterior edge to fit the submandibular triangle and extend to near each ear of the patient. The sling body is at least 4 centimeters long in the anterior-posterior dimension, and the ends of the two lateral sling extensions are at least 14 centimeters distant from each other.

Abstract: An embolic protection device for transvascular delivery to an aortic arch of a patient for protection of side branch vessels of said aortic arch from embolic material. The device comprises a support frame, wherein at least a distal or a proximal portion of the support frame is a spring section configured for providing a radial force between the support frame and a wall of the aortic arch when in an expanded state.

Abstract: An esophageal stent including a stent body having a proximal portion and a distal portion. The proximal portion includes an anchoring structure. The stent also includes a valve attached to the distal portion of the stent.

Abstract: An intraluminal device adapted to be positioned in a lumen that experiences peristalsis and method of fixation of an intraluminal device in the lumen, includes a wall configured to the size and shape of a portion of the lumen and at least one core. The at least one core is removably connected with a portion of the device wall. The at least one core is configured to be positioned against the lumen when the wall is positioned in the lumen. In this manner tissue envelopes the core during implantation of the intraluminal device. The at least one core is configured to be axially removable in situ from the tissue enveloping the core after the device has been deployed by disconnecting the core from the portion of the wall in order to explant the intraluminal device from lumen.

Abstract: A tendon repair implant for treatment of a complete or partial thickness tear in the supraspinatus tendon of the shoulder is provided. The implant may incorporate features of rapid deployment and fixation by arthroscopic means that compliment current procedures; tensile properties that result in desired sharing of anatomical load between the implant and native tendon during rehabilitation; selected porosity and longitudinal pathways for tissue in-growth; sufficient cyclic straining of the implant in the longitudinal direction to promote remodeling of new tissue to tendon-like tissue; and, may include a bioresorbable construction to provide transfer of additional load to new tendon-like tissue and native tendon over time.

Abstract: This invention relates generally to a breast implant having an ePTFE layer, a Silicone layer of a breast implant core, and an interface between the ePTFE layer and the Silicone layer.

Abstract: An implant includes: a sinusoidal container that includes: a plurality of projections; a plurality of troughs; and a plurality of smooth interfaces, wherein a smooth interface is interposed between a projection and an adjacent trough for the plurality of projections, troughs, and interfaces to provide a smooth continuous transition between adjacent projections and troughs. A process for making an implant includes: forming a sinusoidal container from a polymer, the sinusoidal container including: a plurality of projections; a plurality of troughs; and a plurality of smooth interfaces, wherein a smooth interface is interposed between a projection and an adjacent trough for the plurality of projections, troughs, and interfaces to provide a smooth continuous transition between adjacent projections and troughs; and providing a filling tube attached to the sinusoidal container to make the implant.

Abstract: A new method for the treatment of ocular disease and injury are provided. The methods involve the administration of a biocompatible implant, the porcine small intestinal serosa (or serous membrane), as graft/patch directly to the eye, for inducing restoration, remodeling, and repair of a tissue in a variety of injuries or conditions in the cornea, conjunctiva, and/or the eyelid due to trauma, diseases, or surgery. A focus on graft interactions, safety profile has been fully defined and the membrane is reasonable in process, easy and convenient to prepare and significant in therapeutic effect. A simple standardized and straightforward method it has been developed to fabricate this ultra-thin, delicate, and transparent material. Derived from well-defined mechanical strength, the graft demonstrates consistency and flexibility than provides agile solutions for the Physician.

Abstract: According to one aspect of the present disclosure, an implant for correcting vision impairment is disclosed. The implant is made from a donor corneal tissue sized and shaped to provide a predetermined refractive correction and reshaping of a cornea. The donor corneal tissue includes a posterior surface and an anterior surface. The posterior surface has a surface profile that is configured to generally correspond to a shape of an implantation site of the cornea.

Abstract: A transplant tissue storage, transport, and/or placement apparatus, including at least some of a transplant device extending from a distal portion to a proximal portion; a tissue support element formed in the distal portion, the tissue support element having an upper surface having a tissue support element configured to support a central portion of transplant tissue, and a transplant tissue securing mechanism with opposing first securing pad and the second securing pad configured for clasping opposing peripheral portions of transplant tissue in a draped configuration; and a lockable arrangement formed in the proximal portion, the lockable arrangement configured to release a secured transplant tissue from the mounting surface, upon actuation.

Abstract: Described herein are intraocular lenses and methods of implantation. In one aspect, the lens includes a shape changing optical element; a force translation element having a first end region coupled to the optical element and a second end region extending towards a ciliary structure, and an attachment portion coupled to the second end region of the force translation element and configured to contact the ciliary structure. The force translation element is configured to functionally transmit movements of the ciliary structure into a force exerted upon the optical element to effect an accommodating and a disaccommodating change of the optical element.

Abstract: Methods of compressing a stented prosthetic heart valve are disclosed. The method including inserting a stented prosthetic heart valve having a self-expandable stent frame into a container, initiating a cooling element in the container, transferring heat through a thermal conductor to cool an interior of the container, reducing a temperature of the self-expandable stent frame while located within the container to a critical temperature of not greater than 8° C., and compressing an outer diameter of the stented prosthetic heart valve while the stented prosthetic heart valve is at the critical temperature.

Abstract: Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes.

Abstract: A tubular valve body has an upstream end and a downstream end, and has a central longitudinal axis, and defines a lumen along the axis. Prosthetic leaflets are disposed within the lumen, and are configured to facilitate one-way movement of fluid through the lumen in an upstream-to-downstream direction. The valve body has a cellular structure defined by a plurality of joists connected at nodes, the joists and nodes delimiting cells of the cellular structure. The nodes include minor nodes at which 2-4 joists are connected, and major nodes at which 6-8 joists are connected. The cells of the cellular structure comprise a first circumferential row of first-row cells. Each of the first-row cells is connected to each of its circumferentially-adjacent first-row cells at a respective one of the major nodes, and is longitudinally delimited by two of the minor nodes. Other embodiments are described.

Abstract: A frame assembly includes a valve body, a plurality of arms that each extend radially outward from the valve body to a respective arm-tip, and a plurality of ventricular legs that are coupled to the valve body and that extend radially outward from the valve body and toward the plurality of arms. A liner lines the lumen. Prosthetic leaflets are attached to the liner within the lumen. A first sheet of flexible material is attached to the plurality of arms. A second sheet of flexible material is attached to the first sheet and extends radially inwards and downstream, and is attached to the valve body. The first sheet, the second sheet, and the liner define an inflatable pouch therebetween. The apparatus defines a plurality of windows from the lumen into the pouch.

Abstract: A stented valve including a generally tubular stent structure that has a longitudinal axis, first and second opposite ends, a plurality of commissure support structures spaced from the first and second ends and extending generally parallel to the longitudinal axis, at least one structural wire positioned between each two adjacent commissure support structures, and at least one wing portion extending from two adjacent commissure support structures and toward one of the first and second ends of the stent structure. The stewed valve further includes a valve structure attached within the generally tubular stent structure to the commissure support structures.

Abstract: A delivery system and method for percutaneous aortic valve (PAV) replacement and apparatus used therein. A temporary aortic valve including a reversibly expandable occluding means surrounds a central catheter mechanism. The temporary valve is positioned within the ascending aorta, just above and downstream from the coronary ostia. The occluding means is configured such that, when fully expanded against the aortic wall, gaps are left that promote continuous coronary perfusion during the cardiac cycle. The temporary valve substitutes for the function of the native aortic valve during its replacement. The native aortic valve is next dilated, and then ablated through deployment of low profile, elongated, sequentially delivered stents. The stent(s) displace the native tissues and remain within the aortic annulus to receive and provide a structure for retaining the PAV. The PAV is delivered, positioned and deployed within the stent(s) at the aortic annulus with precision and relative ease.

Abstract: A medical device system may include a replacement heart valve implant including an expandable anchor member reversibly actuatable between a delivery configuration and a deployed configuration, wherein the replacement heart valve implant includes at least one locking mechanism configured to lock the expandable anchor member in the deployed configuration, and at least one actuator element configured to releasably engage the at least one locking mechanism and actuate the expandable anchor member between the delivery configuration and the deployed configuration. The at least one actuator element may include external threads on a distal portion of each actuator element and a ramp disposed proximal of the external threads.