Abstract: A method and system for provoking gait disorders, such as freezing of gait; usable, for example, for diagnosing and/or treatment thereof. In an exemplary embodiment of the invention, displays of situations calculated to cause freezing of gait are presented to a subject, optionally using virtual reality displays. Optionally or alternatively, incipit freezing of gait is identified using changes in gait parameters, and optionally used to guide attempts at causing freezing of gait. Optionally or alternatively, a portable device is provided which detects incipit freezing of gait and generates a corrective signal to the subject.

Abstract: Patient support apparatuses include a frame, support surface, and a controller. The controller provides notification to a user of a service event relating to the patient support apparatus. The controller limits functionality of a component of the patient support apparatus based upon a severity of the service event. The controller may also, or alternatively, detect when a control is activated by a user and, in response to such activation, determine whether the patient support apparatus has been marked for use or marked for servicing. If marked for use, the controller responds in a first manner, and if marked for service, the controller responds in a different manner. In other embodiments, a method is provided for determining an order in which multiple patient support apparatuses should be service. In still other embodiments, the patient support apparatus automatically changes to an unusable configuration when in need of high priority service.

Abstract: This disclosure describes techniques for generation of sleep quality information based on posture state data. The techniques may include obtaining posture state data sensed by a medical device for a patient, generating sleep quality information based on lying posture state changes indicated by the posture state data, and presenting the sleep quality information to a user via a user interface.

Abstract: A gait authentication system and method is provided. The system includes a mobile computing device configured to be carried by a person while moving with a unique gait. A first sensor (e.g. an accelerometer) is carried by the mobile computing device and generates a first signal. A second sensor (e.g. a gyroscope) is carried by the mobile computing device and generates a second signal. A gait dynamics logic implements an identity vector (i-vector) approach to learn feature representations from a sequence of arbitrary feature vectors carried by the first and second signals. In the method for real time gait authentication, the computing of invariant gait representations are robust to sensor placement while preserving highly discriminative temporal and spatial gait dynamics and context.

Abstract: Systems and methods for obtaining and analyzing biological data are described. In some embodiments, a local user system may perform steps such as receiving a first message including an indication of a stimulus to be applied, applying the stimulus, detecting a biological response to the stimulus, generating first data including an indication of the detected biological response, and transmitting a second message comprising the first data.

Abstract: Systems and methods for processing, transmitting, and displaying data received from a continuous analyte (e.g., glucose) sensor are provided. A sensor system can comprise a sensor electronics module that includes power saving features, e.g., a low power measurement circuit that can be switched between a measurement mode and a low power mode, wherein charging circuitry continues to apply power to electrodes of a sensor during the low power mode. The sensor electronics module can be switched between a low power storage mode and a higher power operational mode via a switch, e.g., a reed switch or optical switch. A validation routine can be implemented to ensure an interrupt signal sent from the switch is valid. The sensor can be physically connected to the sensor electronics module in direct wireless communication with a plurality of different display devices.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.

Abstract: Disclosed are devices, systems and methods for power management in an electronics unit of a sensor device, e.g., such as in a continuous analyte sensor system. In some example embodiments, there is provided a method that includes monitoring, by a controller of a sensor electronics module, counts associated with signals received from a sensor device for a first period of time. The method also includes comparing a number of received counts with one or more benchmarked count thresholds, and determining whether to initiate an operational mode of the sensor electronics module based on the comparison. Related systems, methods, and articles of manufacture are also described.

Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.

Abstract: A total hemoglobin index system derives total hemoglobin (tHb) index value utilizing a depopulated emitter with an index set of LEDs. A patient fails a tHb index test if tHb measurements are trending down and/or tHb values fall below a predefined index threshold. If a patient fails the tHb index test, a high resolution sensor derives a specific tHb measurement utilizing a high resolution set of LEDs. The number of high resolution set LEDs is greater than the number of index set LEDs.

Abstract: Information for assisting a doctor based on the oxygen saturation of an observation target is presented. An endoscope system includes a light source device, an image sensor, an oxygen saturation calculation unit, a distribution pattern generation unit, a disease state score calculation unit, and a monitor. The light source device emits light to irradiate the observation target. The image sensor images the observation target with reflected light of the light, and outputs an image signal. The oxygen saturation calculation unit calculates an oxygen saturation of the observation target based on the image signal. The distribution pattern generation unit generates a distribution pattern showing the distribution of the oxygen saturation. The disease state score calculation unit calculates a disease state score indicating the disease state of the observation target based on the distribution pattern. The monitor displays the disease state score or information based on the disease state score.

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

Abstract: An arousal level assessment system includes at least one first sensor, at least one second sensor, and a processor. The processor acquires driving mode information and assesses which of a manual driving mode or an automated driving mode is selected based on the driving mode information. In a case where the manual driving mode is selected, the processor acquires driving information via the at least one first sensor, acquires physiological information of the driver via the at least one second sensor, and assesses arousal level based on the driving information and the physiological information. In a case where the automated driving mode is selected, the processor acquires the physiological information via the at least one second sensor and assesses the arousal level based on the physiological information without referring to the driving information.

Abstract: A food taste simulation method, applied in a food taste simulation system, comprising: determining food information of target food according to a food simulation trigger signal when receiving the food simulation trigger signal; determining airflow for simulating the taste of the target food according to the food information; and releasing the airflow through an airflow chip disposed in the oral cavity according to the airflow. The safety of food simulation is improved and the effect of food simulation is enriched in this method. A food taste simulation system is also provided.

Abstract: A force measurement system is disclosed herein. The force measurement system includes a force measurement assembly configured to receive a subject thereon, a visual display device having an output screen, and one or more data processing devices operatively coupled to the force measurement assembly and the visual display device. In the one or more embodiments, the force measurement assembly is a static force plate and the visual display device is a head-mounted visual display device or a visual display device having an output screen configured to at least partially circumscribe three sides of a torso of the subject. In one or more other embodiments, the force measurement assembly is a displaceable force plate and the visual display device is a head-mounted visual display device.

Abstract: An image display control apparatus includes: an image obtaining unit that obtains an image of a backbone region that includes at least a portion of the backbone of a subject; an emphasized display target region specifying unit that specifies an emphasized display target region within the backbone region based on the image; a bone metastasis region specifying unit that specifies an osteolytic metastasis region included in the backbone region; and a display control unit that causes images to be displayed by a display unit. The display control unit displays an osteolytic metastasis region that belongs within the emphasized display target region with a greater degree of emphasis than an osteolytic metastasis region outside the emphasized display target region.

Abstract: A method and apparatus to detect environmental triggers of stress and antecedent physiological stress symptoms of a patient, followed up with delivery of stress relieving therapeutic response to the patient and a chronological report of events. An embodiment comprises a first device worn by the patient that contains sensors and can transmit and receive signals and a second device used by the caregiver that can transmit and receive signals. This integrated system continuously monitors environmental triggers and physiological stress indicative parameters of a patient diagnosed with autistic spectrum disorder, or other emotional or physical disorders, and compares these parameters against thresholds for the parameters. These thresholds can be configured automatically by the system—based on past episodes—or manually by the caregiver, or using automatically configured thresholds that are fine-tuned by the caregiver.

Abstract: A system for obtaining and analyzing data for overall joint motion from a plurality of joints of a subject experiencing a movement disorder involves a plurality of kinematic sensors configured to be placed on a body of a subject experiencing a movement disorder proximal a plurality of joints of the subject. The kinematic sensors are selected to measure overall joint motion with sufficient degrees of freedom for individual joints so that data collected by the sensors can be deconstructed into multiple degrees of freedom for individual joints and analyzed to provide amplitude of the movements caused by the movement disorder and/or relative contributions from and/or directional bias for each muscle group that may be implicated in the movement of each joint.

Abstract: Device and method for determining an efficacy of chronic pain treatment including providing a first set of at least one stimulus to a subject, obtaining first measurements of at least two physiological parameters in response to the first set of at least one stimulus, providing chronic pain treatment to the subject, providing a second set of at least one stimulus to the subject, obtaining second measurements of the at least two physiological parameters in response to the second set of at least one stimulus; and determining an efficacy of the chronic pain treatment by applying a classification algorithm on the first and second measurements of the at least two physiological parameters.

Abstract: The present invention relates to a device (10) and method for non-invasively measuring a hydration state of a living being (62). To improve with respect to the convenience-to-use, the cost-effectiveness and the accuracy of the delivered results, the proposed device comprises a first light source (14) for emitting light of a first wavelength into a tissue portion (12) of the living being (62), polarization means (18) for polarizing at least part of the emitted light prior to an interaction of the emitted light with the tissue portion (12), a first light detector (26) for detecting polarized light of the first wavelength reflected at the tissue portion (12) and processing means (32) configured to derive a tissue hydration parameter from the detected reflected polarized light and to determine a body hydration index based on said tissue hydration parameter.

Abstract: Systems and methods for determining an instant messaging (IM) status of a user wearing a smart watch are disclosed. A computing device includes: a processor; a memory; and sensors including at least one biometric sensor, at least one location sensor, and at least one orientation sensor. The memory stores a status application that is executed by the processor and is configured to: obtain real time data from at least one of the sensors; determine an instant messaging (IM) status based on the real time data; and transmit the IM status to a server for providing to other IM users.

Abstract: An equine performance tracking and monitoring system having real-time feedback may include a horse heart rate monitoring strap configured to be secured against a portion of a horse while extending only part of the way around the horse. To measure the horse's heart rate, the disclosed systems may utilize such a discrete-length horse heart rate monitoring strap having electrodes, one of which is positioned behind the left elbow of the horse. The horse's heart rate may be transmitted to a wearable device work by a rider. The wearable device may include a sensor configured to measure the heart rate of the rider. The heart rate of the horse and the heart rate of the rider may each be presented to the rider, for example, via a display of the wearable device.

Abstract: Systems and methods are disclosed for proximity sensing in physiological sensors, and more specifically to using one or more proximity sensors located on or within a physiological sensor to determine the positioning of the physiological sensor on a patient measurement site. Accurate placement of a physiological sensor on the patient measurement site is a key factor in obtaining reliable measurement of physiological parameters of the patient. Proper alignment between a measurement site and a sensor optical assembly provides more accurate physiological measurement data. This alignment can be determined based on data from a proximity sensor or sensors placed on or within the physiological sensor.

Abstract: A circuit (32) for use in an magnetic resonance (MR) system to reduce MR interference of a physiological signal S(f) includes a first summing/subtraction node (36), a high pass filter (40), and a second summing/subtraction node (42). The first summing/subtraction node (36) inputs a first signal (34) including radio frequency magnetic interference N(f) and a physiological signal S(f), and a second signal (38) including the physiological signal S(f) and an error signal E(f), and subtractively combines the second signal with the first signal to generate a difference signal N(f)?E(f). The high pass filter (40) filters the difference signal N(f)?E(f) from the first summing/subtraction node. The second summing/subtraction node (42) subtractively combines the first signal S(f)+N(f) (34) and the filtered signal H(f)*[N(f)?E(f)] from the high pass filter, and generates the second signal S(f)+E(f) (38).

Abstract: In one embodiment, an ECG signal processing apparatus is configured to be connected with an electrocardiograph and an MRI apparatus and includes memory circuitry and processing circuitry configured to (a) store a parameter of an ECG signal as a first parameter in the memory circuitry, the ECG signal being acquired from the electrocardiograph operating in combination with the MRI apparatus in a period during which a gradient pulse is not applied by the MRI apparatus, (b) implement an adaptive filter for estimating noise mixed into the ECG signal due to the gradient pulse, by using the first parameter stored in the memory circuitry and a gradient magnetic field signal acquired from the MRI apparatus in a period during which the gradient pulse is applied, and (c) remove the noise mixed into the ECG signal in the period during which the gradient pulse is applied, by using estimated noise.

Abstract: A method for determining a stress level of a user based on a sympathovagal balance (SVB) value calculated based on a set of measurement data may include determining a heart-rate variability (HRV) characteristic as a ratio involving a number of autonomic nervous system (ANS) activity markers within a first portion of the set of measurement data and the number of ANS activity markers within a second portion of the set of measurement data, and then determining the stress level of the user based on the HRV characteristic. The first and second portions of the set of measurement data may be selected based on a user-specific baseline SVB value that divides a histogram representation of the set of measurement data into the first and second portions.

Abstract: A biosensor unit is coupled to a user device and may communicate with the user device over a short range wireless or wired interface. The biosensor unit includes an optical sensor used to obtain an oxygen saturation level, a heart rate and a respiration rate of a user. The biosensor unit may also obtain a blood pressure and a temperature of the user using one or more other sensors. The biosensor unit transmits the obtained biosensor data to the user device using the short range interface.

Abstract: A device for detecting biometric information is provided. The device includes a housing, a fastener coupled to a part of the housing and detachably attached to a part of a user's body, at least one first sensor configured to detect the motion of the electronic device, at least one second sensor configured to detect a change in the user's body, a memory, and a processor electrically connected to the at least one first sensor, the at least one second sensor, and the memory.

Abstract: A portable patient monitor has an integrated mode in which it operates as a plug-in module for a multiparameter patient monitoring system (MPMS). The patient monitor also has a portable mode in which it operates separately from the MPMS as a battery-powered handheld or standalone instrument. The patient monitor has a sensor port that receives a signal indicative of physiological parameters as input to an internal processor. The patient monitor processes this sensor signal to derive patient measurements. In the portable mode, this information is provided on its display. In the integrated mode, the patient monitor provides patient measurements to the MPMS to be displayed on a MPMS monitor.

Abstract: Systems and methods for wirelessly controlling medical devices are provided. One system includes a portable user interface having a housing and a communication module within the housing configured to wirelessly communicate with at least one medical device. The portable user interface also includes a display displaying a graphical user interface to control the at least one medical device remotely, wherein the displayed graphical user interface corresponds to a control interface of the at least one medical device.

Abstract: A radiation detector (16) having a first detector layer (24) and a second detector layer (26) encircles an examination region (14). Detectors of the first layer include scintillators (72) and light detectors (74), such as avalanche photodiodes. The detectors of the second detector layer (26) include scintillators (62) and optical detectors (64). The scintillators (72) of the first layer have a smaller cross-section than the scintillators (62) of the second layers. A group, e.g., nine, of the first layer scintillators (72) overlay each second group scintillator (62). In a CT mode, detectors of the first layer detect transmission radiation to generate a CT image with a relatively high resolution and the detectors of the second layer detect PET or SPECT radiation to generate nuclear data for reconstruction into a lower resolution emission image. Because the detectors of the first and second layers are aligned, the transmission and emission images are inherently aligned.

Abstract: A proton radiography system includes a source of a proton beam at nonrelativistic energy, directed on a beam path to an object to be imaged; one or more time-of-flight (TOF) detectors arranged on the beam path to detect incidence of beam protons and generate output signals indicative thereof with a time resolution substantially less than a time of flight of the protons; and a data acquisition and analysis subsystem coupled to the TOF detectors to receive the respective output signals and (1) calculate TOF values for respective bunches of one or more protons, (2) convert the TOF values to proton velocity values and proton energy values, and (3) use the proton energy values to calculate a corresponding value for a physical property of the object along the beam path, and incorporate the value into elements of a radiographic image of the object stored or displayed in the system.

Abstract: A heat formable patient positioning cushion is provided including an impermeable or permeable outer shell; a filler material contained within an interior region defined by the outer shell; and a thermoplastic material applied to the outer shell, to the filler material, or to the outer shell and the filler material. The cushion has a first condition configured to be conformed to the anatomy of a patient in which the filler material moves relatively freely within the interior region defined by the outer shell, and a second condition conformed to the anatomy of the patient in which the filler material is relatively fixed against movement within the interior region defined by the outer shell. Heating and cooling changes the cushion from the first condition to the second condition and reheating permits increased movement of the filler material as compared to the second condition to further conform the cushion to the anatomy of the patient.

Abstract: A method and apparatus for acquiring a radiographic image of a patient includes using an X-ray source and at least a X-ray detector supported in opposed positions, the area under investigation being positioned between the X-ray source and detector in the propagation bundle of the radiation emitted by the X-ray source, the X-ray source and detector being movable along a pre-set trajectory due to at least two movements. The X-ray dose administered to a patient can be adjusted automatically, dispensing the minimum dose necessary to achieve a radiographic image of good quality. The method and apparatus provide for performing a scout acquisition, preceding the acquisition of a real panoramic image, in a particularly efficient way. During the scout acquisition, data are collected for adjusting the X-ray dose for the following radiographic image acquisition.

Abstract: Apparatuses are disclosed for permitting a user to manipulate a sensor. The apparatuses have a handle, an arm, and a sensor mounting head. The sensor may be removably affixed to the sensor mounting head by the user. The arm is permanently flexible so that the user may adjust the position of the affixed sensor to any arbitrary position with respect to the handle. The apparatuses are capable of using wired and wireless sensors. In one embodiment, the handle contains a power source which supplies energy to operate a wireless sensor.

Abstract: A breast imaging apparatus includes a gantry which includes a radiation generation unit configured to generate radiation and a radiation detection unit configured to detect radiation generated by the radiation generation unit, the radiation generation unit and the radiation detection unit being capable of rotating facing each other, wherein the gantry is provided with a front cover configured to protect a subject from the radiation generation unit and the radiation detection unit which rotate during CT imaging, and the front cover has an opening in which the breast of the subject is inserted, and a breast holding portion configured to hold the breast of the subject inserted in the opening.

Abstract: An imaging system (100) includes a radiation source (108) that emits radiation that traverses an examination region and imageable drug eluting beads in tissue of interest located therein, a spectral detector array (110) detects radiation traversing the examination region and generates a signal indicative thereof, spectral processing circuitry (117) that spectrally resolves the signal based on a plurality of thresholds (122), and a reconstructor (128) that generates spectral volumetric image data corresponding the imageable drug eluting beads based on the spectrally resolved signal.

Abstract: A method operates an x-ray system for examining an object. In order to optimize the operation of an x-ray system, in particular the dose regulation and/or the image processing, the following method steps are performed. Radiation is passed through the object to be examined and a number of fluoroscopic images of the object are generated. A relevant image region of a fluoroscopic image is selected by a user of the x-ray system. An image-based dose regulation of the radiation dose used for passing radiation through the object is carried out using the selected image region and/or image processing is carried out using the selected image region.

Abstract: A system including initialization, imaging, alignment, processing, and setting modules. The initialization module obtains patient parameters for a patient and procedure and surgeon parameters. The initialization module selects first settings for an x-ray source based on the patient, procedure, and surgeon parameters. The image module obtains a first sample set of images of a region-of-interest of the patient and a master sample set of images. The first sample set was acquired as a result of the x-ray source operating according to the first settings. The alignment module aligns the first sample set to the master sample set. The processing module processes pixel data corresponding to a result of the alignment based on a pixel parameter or one of the patient parameters. The setting module adjusts the first settings to provide updated settings. X-ray dosage associated with the updated settings is less than x-ray dosage associated with the first settings.

Abstract: An x-ray imaging system utilizes enhanced computing arrays. A plurality of x-ray illumination source positions are utilized to produce x-ray radiation at each of the x-ray illumination source positions and to project x-ray radiation towards an object. A detector detects x-ray radiation from the object and transmits detector images for each of the illumination source positions. A memory buffer stores the detector images from the detector. A graphics processing unit formats the detector images and constructs a complete frame data set with the detector images for each of the illumination source positions. Another graphics processing unit receives the complete frame data set and performs image reconstruction on the complete frame data set.

Abstract: The distance between the radiation source and an object (SOD value) is acquired, distance dependent information which is obtained from a radiation image and changes with the distance between a radiation source and a radiation detector (SID value) is acquired, a temporary thickness of the object is determined by a first function representing the correspondence relationship of first information having at least one piece of the distance dependent information, the SID value, and the thickness of the object, and the temporary SID value is determined by adding the SOD value to the determined value. The thickness of the object is determined by a second function representing the correspondence relationship of second information having at least one piece of the distance dependent information, the SID value, and the thickness of the object, and the SID value is determined by adding the SOD value to the determined value.

Abstract: Provided is an X-ray imaging apparatus including: an image generation unit configured to generate an X-ray image based on X-rays transmitted by an object; a thickness measurement unit configured to measure thickness information of the object and generate a reference phantom image in which the measured thickness information is indicated; and an image separation unit configured to generate a final image obtained by separating a material inside the object from the X-ray image using the reference phantom image.

Abstract: The X-ray imaging device includes an irradiation unit which includes an X-ray tube and a collimator; and a tape measure which has a scale band on which distances from the irradiation unit are printed so as to increase from one end to the other and a winding mechanism that holds and winds the other end of the scale band. The irradiation unit has a scale band fixing portion which fixes one end of the scale band, and a winding mechanism fixing portion which fixes the winding mechanism.

Abstract: An audible ultrasound physical examination device alters ultrasound to an audible range such that audible feedback can be used to enhance physical examination to detect anatomical abnormality and determine if more refined testing is warranted. The device includes a chestpiece and an ultrasound probe coupled to the chestpiece. The ultrasound probe projects an initial sound wave towards a first face of the chestpiece and into a human body such that a reflected wave is produced when the initial sound wave is reflected by matter with the human body. A sonic converter, coupled to the chestpiece, introduces an interference wave creating destructive interference to produce a resulting wave within an audible range. An earpiece is coupled to the chestpiece such that the resulting wave in the audible range is audible through the earpiece.

Abstract: An abdominal statistics system including a low profile rapidly deployable sensor element having an acoustic sensor and vibration actuator that can be conveniently attached to the abdomen of a patient. The system acquires acoustic signals as gastrointestinal (GI) sounds, processes these signals, and provides actionable data to patients and their providers.

Abstract: An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a mitral valve, including the automatic indication of the location of a regurgitant orifice in an ultrasound image. A clinician images the regurgitant valve and indicates in the image the presumed location of the regurgitant orifice (130). A flow quantification processor is responsive to this initial location estimate by the clinician to calculate a refined estimation of the orifice location. The refined location is indicated on the ultrasound image by the imaging system, either by relocating an icon placed by the clinician, or displaying a second icon (132) on the image at the refined location.

Abstract: A device is configured for interrogating a blood vessel to derive flow characteristics (S628) and for, responsive to the deriving and based on the derived characteristics, anatomically identifying the vessel. A spatial map of the vessels may be generated based on the interrogating, and specifically the Doppler power computed from data acquired in the interrogating. Subsequent interrogating (S668) may occur, based on the map and on a user-selected set of vessels and/or vessel categories, to derive clinical Doppler indices. The device can be designed to automatically set a sample volume (509) for the subsequent interrogating, and to operate automatically from the user selection to display of the indices. The display may further include an image (524) of the vessels summoned by the set, annotated by their individual anatomical names, and optionally a diagnosis relating to blood flow. The displayed image may be enlarged to zoom in on the user's onscreen selection.

Abstract: Apparatus and methods of use are provided for complex flow imaging and analysis that is non-invasive, accurate, and time-resolved. It is particularly useful in imaging of vascular flow with spatiotemporal fluctuations. This apparatus is an ultrasound-based framework called vector projectile imaging (VPI) that can dynamically render complex flow patterns over an imaging view at millisecond time resolution. The VPI apparatus and methods comprise: (i) high-frame-rate broad-view data acquisition (based on steered plane wave firings); (ii) flow vector estimation derived from multi-angle Doppler analysis (coupled with data regularization and least-squares fitting); and (iii) dynamic visualization of color-encoded vector projectiles (with flow speckles displayed as adjunct).

Abstract: A method for characterizing tissue of a patient, including receiving acoustic data derived from the interaction between the tissue and the acoustic waves irradiating the tissue; generating a morphology rendering of the tissue from the acoustic data, in which the rendering represents at least one biomechanical property of the tissue; determining a prognostic parameter for a region of interest in the rendering, in which the prognostic parameter incorporates the biomechanical property; and analyzing the prognostic parameter to characterize the region of interest. In some embodiment, the method further includes introducing a contrast agent into the tissue; generating a set of enhanced morphology renderings of the tissue after introducing the contrast agent; determining an enhanced prognostic parameter from the enhanced morphology renderings; and analyzing the enhanced prognostic parameter.

Abstract: An medical device guide system includes a probe configured for imaging portions of a patient's body, a first guide connector extending from a first surface of the probe, the first guide connector including a first mounting surface, and a guide removably mountable to the first guide connector. The guide may include a first cavity shaped to receive the first mounting surface and a first channel disposed on a top surface of the guide opposite the first cavity, the first channel angled at a first angle with respect to a longitudinal axis of the probe and configured to guide a medical device to a targeted depth in the patient's body.