Patents Issued in May 28, 2019
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Patent number: 10299699Abstract: Methods, apparatuses and computer program products implement embodiments of the present invention that include receiving, from an imaging system operating in an image coordinate system, a three-dimensional image of a body cavity including open space and body tissue, and receiving, from a medical probe having a location sensor and inserted into the body cavity, a signal indicating a location of a distal tip of the medical probe in a sensor coordinate system. The image coordinate system is registered with the sensor coordinate system so as to identify one or more voxels in the three-dimensional image at the indicated location, and when the identified voxels have density values in the received three-dimensional image that do not correspond to the open space, the density values of the identified voxels are updated to correspond to the open space.Type: GrantFiled: November 28, 2016Date of Patent: May 28, 2019Assignee: Biosense Webster (Israel) Ltd.Inventors: Assaf Govari, Vadim Gliner
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Patent number: 10299700Abstract: A system for supplying energy to a medical device implanted in a mammal patient. The system comprises an external energy source adapted to be externally arranged to the patient's body and configured to wirelessly transmit energy for powering the medical device. The system further comprises an internal energy receiver adapted to be implanted in the patient's body and configured to receive energy, transmitted from the external energy source, for supplying energy or control signals to the medical device, and a control unit configured to control the amount of energy received by the internal energy receiver, wherein said control unit is configured to control based on a parameter indicating a characteristic of the medical device or a characteristic of the patient's condition.Type: GrantFiled: January 16, 2018Date of Patent: May 28, 2019Inventor: Peter Forsell
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Patent number: 10299701Abstract: A compact, on-airway, respiratory gas analyzer for performing pulmonary function tests incorporates an IR spectroscopy light guide having a curved, rather than linear, sample chamber that lies transverse to a direction of respiratory gas flow. Cooperating with the sample chamber is an impact plate that functions to steer respiratory and test gases impinging on the impact plate into the curved sample chamber. A source of IR energy is at one end of the sample chamber and an electro-optical sensor responsive to IR energy is disposed at an opposite end of the chamber. The respiratory gas analyzer also includes gas flow paths and valving for carrying out lung capacity and lung diffusion tests.Type: GrantFiled: May 6, 2016Date of Patent: May 28, 2019Assignee: MGC Diagnostics Corp.Inventors: David A. Blanton, Charles P. Howard
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Patent number: 10299702Abstract: Devices and methods for determining various occurrences and anomalies within a step are provided. A device to determine characteristics of a step includes at least one sensor to measure acceleration of a foot in at least two directions, at least one processor to execute instructions stored in a memory and to determine accelerations in first and/or second directions meet criteria to determine a footstrike and a push off of a foot from a surface. Slipping of feet while walking and running, clipping of feet while walking and running, and tripping and falling while walking and running may be indicators of overall health and fitness, particularly in older individuals.Type: GrantFiled: November 11, 2015Date of Patent: May 28, 2019Assignee: Zwift, Inc.Inventors: Stephen Suydam, Meir Machlin, Jason Kaplan
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Patent number: 10299703Abstract: The present disclosure relates to various methods for determining a neuromuscular blockade status and systems suitable for performing such methods. The present disclosure further relates to electro-stimulation electrodes for stimulating a muscle of a patient, optionally in the context of at least some of the mentioned methods. The present disclosure still further relates to hybrid air-signal connectors for use in an electro-stimulation cuff which can be used in the context of at least some of the cited methods. The present disclosure also relates to electro-stimulation circuits comprising an electrode portion and a track portion suitable for pressure cuffs for electro-stimulation, and to pressure cuffs configured to be arranged around a limb of a patient and comprising an active electro-stimulation electrode and a passive electro-stimulation electrode. These electro-stimulation circuits and pressure cuffs may also be used in the context of at least some of the mentioned methods.Type: GrantFiled: June 23, 2016Date of Patent: May 28, 2019Assignees: RGB MEDICAL DEVICES S.A., FUNDACIÓ EURECATInventors: José Javier Rodiera Olivé, Paul Dominique Lacharmoise
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Patent number: 10299704Abstract: A method for monitoring activity of a subject in an environment, comprising providing at least one sensing assembly in the environment of the subject; providing a server communicating with at least one of: i) the subject and ii) the at least one sensing assembly; generating property vectors from data collected by the at least one sensing assembly; characterizing activity of the subject from the property vectors; and having a result of said characterizing step accessible to the server.Type: GrantFiled: March 1, 2017Date of Patent: May 28, 2019Assignee: GROUPE EVERCLOSE INC.Inventor: Christian Cloutier
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Patent number: 10299705Abstract: Embodiments of the present disclosure disclose an estimation device for the estimation of Sound Recognition Score. The device estimates a Sound Recognition Score (SRS), to determine the hearing ability of that subject. The device also ascertains the performance of an Augmented Listening Device (ALD). The device comprises a memory unit, in which one or more audio signals and ambient noise signals are stored. The estimation device selects audio signal from the memory unit based on one or more parameters. Further, the device modulates the audio signals with the ambient noise signals and transmits the modulated audio signal to the ALD. Also, the device receives response for the transmitted signals from the ALD and estimates the responses based on the aggregate of values of the read flag data and response flag data. The estimated signal is displayed using a display unit as Sound Recognition Score.Type: GrantFiled: February 1, 2016Date of Patent: May 28, 2019Assignee: Centre for Development of Advanced ComputingInventors: Vishnu Venugopal Ambika, Gopakumar Gopinathan Nair, Krishnakumar Rao Sanjeeva Rao, Biju Cheriyan Oommen
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Patent number: 10299706Abstract: A method and apparatus for non-invasive blood glucose measurement are disclosed. The methods and apparatus utilize exposing a biological object supplied with blood and capable of transmitting infrared radiation therethrough, to an incident beam of polarized infrared radiation with a given angular position of a polarization plane, determining an angular position of a polarization plane of the radiation transmitted through the biological object with a polarizer-analyzer, and measuring an angle shift between said angular positions of the polarization planes of the incident and transmitted radiation, and calculating a glucose concentration C. The methods and apparatus further utilize measuring the length and oscillations of a whisker connected to the polarizer-analyzer and to a rigid support so as to calculate the instantaneous positions of the polarizer-analyzer.Type: GrantFiled: June 15, 2016Date of Patent: May 28, 2019Inventor: Mark Bosin
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Patent number: 10299707Abstract: The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.Type: GrantFiled: April 18, 2017Date of Patent: May 28, 2019Assignee: STC.UNMInventors: John B. Plumley, Erin D. Milligan, Marek Osinski
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Patent number: 10299708Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.Type: GrantFiled: January 29, 2019Date of Patent: May 28, 2019Assignee: MASIMO CORPORATIONInventors: Jeroen Poeze, Marcelo Lamego, Sean Merritt, Cristiano Dalvi, Hung Vo, Johannes Bruinsma, Ferdyan Lesmana, Massi Joe E. Kiani, Greg Olsen
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Patent number: 10299709Abstract: The present disclosure describes the derivation and measurement of a fractional oxygen saturation measurement. In one embodiment, a system includes an optical sensor and a processor. The optical sensor can emit light of multiple wavelengths directed at a measurement site of tissue of a patient, detect the light after attenuation by the tissue, and produce a signal representative of the detected light after attenuation. The processor can receive the signal representative of the detected light after attenuation and determine, using the signal, a fractional oxygen saturation measurement based on two or more different measures of fractional oxygen saturation.Type: GrantFiled: October 26, 2017Date of Patent: May 28, 2019Assignee: MASIMO CORPORATIONInventors: Philip Perea, Ammar Al-Ali, Massi Joe E. Kiani
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Patent number: 10299710Abstract: An organism optical measurement device having a light transmitter/receiver control unit for obtaining measurement data concerning brain activities and a measurement data display control unit for displaying the measurement data. The organism optical measurement device is further provided with a head surface appearance image acquiring unit for acquiring a head surface appearance image of a subject, a head surface appearance image display control unit for displaying the head surface appearance image, and a measurement-related position calculating unit for calculating the measurement-related position in the head surface appearance image from which the measurement data is obtained when an input device specifies the positions in the head surface appearance image corresponding to the positions of a light transmitting probe and a light receiving probe disposed on the head surface of the subject.Type: GrantFiled: July 21, 2009Date of Patent: May 28, 2019Assignee: SHIMADZU CORPORATIONInventor: Akihiro Ishikawa
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Patent number: 10299711Abstract: A universal electrochemical micro-sensor can be used either as a biosensor or an environmental sensor. Because of its small size and flexibility, the micro-sensor is suitable for continuous use to monitor fluids within a live subject, or as an environmental monitor. The micro-sensor can be formed on a reusable glass carrier substrate. A flexible polymer backing, together with a set of electrodes, forms a reservoir that contains an electrolytic fluid chemical reagent. During fabrication, the glass carrier substrate protects the fluid chemical reagent from degradation. A conductive micromesh further contains the reagent while allowing partial exposure to the ambient biological or atmospheric environment. The micromesh density can be altered to accommodate fluid reagents having different viscosities. Flexibility is achieved by attaching a thick polymer tape and peeling away the micro-sensor from the glass carrier substrate.Type: GrantFiled: January 17, 2018Date of Patent: May 28, 2019Assignee: STMICROELECTRONICS PTE. LTD.Inventors: Olivier Le Neel, Suman Cherian, Calvin Leung
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Patent number: 10299712Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.Type: GrantFiled: September 5, 2017Date of Patent: May 28, 2019Assignee: DexCom, Inc.Inventors: Mark C. Brister, James R. Petisce, Peter C. Simpson
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Patent number: 10299713Abstract: The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media.Type: GrantFiled: September 26, 2014Date of Patent: May 28, 2019Assignee: Magnolia Medical Technolgies, Inc.Inventor: Richard G. Patton
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Patent number: 10299714Abstract: Disclosed are devices for collecting and stabilizing blood that contain a blood stabilization agent which includes variegin or an analog thereof, a polysulfated disaccharide, or a combination thereof, each in an amount effective to stabilize blood. Methods of making and using the devices, and kits containing the devices, are also provided.Type: GrantFiled: December 2, 2011Date of Patent: May 28, 2019Assignee: Becton, Dickinson and CompanyInventors: Craig A. Gelfand, Daniel Marchiarullo, Keith Moskowitz
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Patent number: 10299715Abstract: Method and device for monitoring stress of an individual in a moving structure by estimating and monitoring a mental component of a total heart rate of the individual, wherein the total heart rate comprises the mental component, a mechanical component, a component relating to heat balance and a component relating to basic metabolic functions, wherein the total heart rate and movements of the individual and the moving structure are measured in real-time, wherein the mechanical component is estimated in real-time based on the real-time movement of the individual and the moving structure, wherein the mental component is obtained by subtracting the mechanical component, the component relating to the heat balance and the component relating to basic metabolic functions from the total heart rate.Type: GrantFiled: June 22, 2015Date of Patent: May 28, 2019Assignee: BIORICS N.V.Inventors: Daniel Berckmans, Vasileios Exadaktylos
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Patent number: 10299716Abstract: Apparatus, systems, and/or methods may provide a mental state determination. For example, a data collector may collect image data for a side of a face of a user from an image capture device on the user (e.g., a wearable device). The image data may include two or more perspectives of a feature on the side of the face of the user. In addition, a state determiner may determine a mental state of the user based on the image data. In one example, fields of view may be combined to determine a total region and/or a total overlap region. Changing the position that one or more image capture devices point may modulate the total region and/or the total overlap region. In addition, one or more sensors may be utilized to further improve mental data determinations.Type: GrantFiled: December 22, 2016Date of Patent: May 28, 2019Assignee: Intel CorporationInventors: Cagri Tanriover, Sinem Aslan, Nese Alyuz Civitci, Ece Oktay, Eda Okur, Asli Arslan Esme
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Patent number: 10299717Abstract: Described herein are systems and methods for detecting a stress level of a user. In one embodiment, a system includes an inward-facing head-mounted thermal camera (CAM) and a computer. CAM takes thermal measurements of a region on a periorbital area (THROI1) of the user. The computer generates feature values based on THROI1, and utilizes a model to detect the stress level based on the feature values. The model was trained based on: previous THROI1 taken while the user was under elevated stress, and other previous THROI1 taken while the user was not under elevated stress. Some embodiments may utilize additional thermal cameras that take thermal measurements of other regions on the face, which may be utilized to detect the stress level.Type: GrantFiled: December 6, 2017Date of Patent: May 28, 2019Assignee: Facense Ltd.Inventors: Arie Tzvieli, Gil Thieberger, Ari M Frank
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Patent number: 10299718Abstract: The present invention relates to a system device and method for monitoring infant oral motor kinetics (OMK), which can be used to assess the functional significance of the different sucking components, i.e., the plasticity of infant sucking skills in relation to their oral feeding performance, at a particular time, during the developmental period and/or during preventive or therapeutic intervention programs. It is a unique system and apparatus that provides a means to study the nonnutritive and/or nutritive sucking skills, i.e., the Suction and/or Expression components of sucking, of infants in the natural setting, i.e., during a normal feeding session.Type: GrantFiled: January 17, 2017Date of Patent: May 28, 2019Inventor: Chantal Lau
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Patent number: 10299719Abstract: Parametric model based computer implemented methods for determining the stiffness of a bone, systems for estimating the stiffness of a bone in vivo, and methods for determining the stiffness of a bone. The computer implemented methods include determining a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f) and fitting a parametric mathematical model to Y(f) and to H(f). The systems include a device for measuring the stiffness of the bone in vivo and a data analyzer to determine a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f). The methods for determining the stiffness include fitting a parametric model to stiffness of the skin-bone complex as a function of frequency H(f) and the compliance of the skin-bone complex as a function of frequency Y(f).Type: GrantFiled: April 11, 2014Date of Patent: May 28, 2019Assignee: Ohio UniversityInventors: Lyn Bowman, Patricia A. Arnold, Emily R. Ellerbrock
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Patent number: 10299720Abstract: The present invention generally relates to compositions comprising anesthesia-reversing agents which facilitate or increase the time of awakening or reverse the effects of general anesthesia-induced unconsciousness. In some embodiments, the anesthesia reversing agent can be selected from any or a combination of methylphenidate (MPH), amphetamine, modafinil, amantadine, caffeine, or analogs or derivatives thereof. In some embodiments, compositions comprising at least one or more anesthesia-reversing agents can be used to facilitate awakening from anesthesia without or decreasing occurrence of delirium, and can be used in methods to treat or prevent the symptoms associated with emergence delirium, as well as treat a subject oversedated with general an esthesia. The invention also relates to methods for administering these compositions comprising anesthesia-reversing agents to subjects and for use.Type: GrantFiled: February 10, 2015Date of Patent: May 28, 2019Assignee: The General Hospital CorporationInventors: Emery N. Brown, Patrick L. Purdon
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Patent number: 10299721Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.Type: GrantFiled: July 21, 2016Date of Patent: May 28, 2019Assignee: AccuVein, Inc.Inventors: Fred Wood, Ron Goldman, Stephen P Conlon, Vincent Luciano
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Patent number: 10299722Abstract: A footwear having a sole customized to a wearer's anatomy, the sole formed by receiving a 3D model of a sole having a volume, generating a structural lattice inside the volume of the sole, updating the structural lattice to provide strength while using reduced material, optimizing the structural lattice to maximize energy absorption by the sole, and 3D fabricating the sole with the optimized structural lattice; and sensors coupled to the sole to detect foot pressure and movement data.Type: GrantFiled: February 3, 2016Date of Patent: May 28, 2019Inventor: Bao Tran
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Patent number: 10299723Abstract: A moisture-sensitive device is provided that includes a dissolvable conductive material. Exposure of the dissolvable conductive material to urine or some other fluid causes the dissolvable conductive material to dissolve, increasing an effective resistance of the dissolvable conductive material. This change in resistance can be detected to determine the presence of an aqueous fluid. In response to such detection, a transmitter can then provide a wireless transmission indicative of the presence of the fluid. This moisture-sensitive device can be provided in a diaper and transmissions produced by the device can be detected using a smart phone or other device and used to indicate to a user that the diaper has been soiled.Type: GrantFiled: June 6, 2017Date of Patent: May 28, 2019Assignee: Verily Life Sciences LLCInventors: Brian Pepin, Robert Wiser
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Patent number: 10299724Abstract: A wristwatch includes a case containing electronic components of the wristwatch. An optoelectronic module including at least one light emitting element and at least one light sensing element is disposed within the case or within a fastener for the wristwatch. The optoelectronic module is operable to obtain physiological data of a person wearing the wristwatch by using the light emitting element and the light sensing element.Type: GrantFiled: April 28, 2014Date of Patent: May 28, 2019Assignee: ams Sensors Singapore Pte. Ltd.Inventor: Ohad Meitav
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Patent number: 10299725Abstract: Wearable devices are described herein including at least two photodetectors and a mount configured to mount the at least two photodetectors to an external surface of a wearer. The at least two photodetectors are configured to detect alignment between the wearable device and a target on or in the body of the wearer (e.g., to detect the location of vasculature within the body of the wearer relative to the at least two photodetectors). Alignment of the at least two photodetectors relative to the target could enable detection of one or more physiological properties of the wearer. For example, the wearable device could include a sensor configured to detect a property of the target when the sensor is above the target, and alignment of the target relative to the at least two photodetectors could include the sensor being located above the target.Type: GrantFiled: March 27, 2017Date of Patent: May 28, 2019Assignee: Verily Life Sciences LLCInventors: Russell Norman Mirov, Andrew Homyk, Mark West Askew, Jason Donald Thompson
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Patent number: 10299726Abstract: A bodily information measurement apparatus includes a band-shaped belt to be wrapped around a measurement site; a main body that is connected to a base end portion in the lengthwise direction of the belt and on which a pressure detection unit and a fluid supply unit are mounted; and a fastening unit for fastening the base end portion and the leading end portion of the belt. The belt is formed by stacking an outer circumferential layer and a fluid bladder for compressing the measurement site. The bodily information measurement apparatus is attached to the measurement site due to the base end portion and the leading end portion being fastened by the fastening portion in a state in which the fluid bladder and the leading end portion of the belt overlap.Type: GrantFiled: February 28, 2018Date of Patent: May 28, 2019Assignee: OMRON HEALTHCARE Co., Ltd.Inventors: Yoshihide Tokko, Ryosuke Doi, Yuma Adachi, Chisato Tawara, Minoru Taniguchi, Masayuki Fukutsuka, Eisuke Yamazaki
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Patent number: 10299727Abstract: The present invention provides a coronary sinus inspiration catheter comprising a catheter head section and an extension tube, which are hollow tubular structures, the catheter head section and a distal section of the extension tube are substantially arc-shaped, the catheter head section comprises an arc section and a bend section, and its length is about 4-10 cm, the distal end is small (3-6 F) and the tube diameter of the catheter head section increase gradually toward the proximal end (6-12 F), the catheter head section is bent at a 15-45° angle at the position which has a distance of 0.5-1.5 cm from the distal end, the bend section is a straight or slightly arc-shaped structure. The catheter head section is provided with an end hole and a plurality of side holes, and is equidistantly provided with radiopaque markers from the distal end to the proximal end.Type: GrantFiled: August 17, 2016Date of Patent: May 28, 2019Inventor: Shengxian Fang
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Patent number: 10299728Abstract: An initial set of parameters for operating one or more detection tools is automatically derived and subsequently adjusted so that each detection tool is more or less sensitive to signal characteristics in a region of interest. Detection tool(s) may be applied to physiological signals sensed from a patient (such as EEG signals) and may be configured to run in an implanted medical device that is programmable with the parameters to look for rhythmic activity, spike activity, and power changes in the sensed signals, etc. A detection tool may be selected, and parameter values derived in a logical sequence and/or in pairs based on a graphical representation of an activity type which may be selected by a user, for example, by clicking and dragging on the graphic via a GUI. Displayed simulations allow a user to assess what will be detected with a derived parameter set and then to adjust the sensitivity of the set or start over as desired.Type: GrantFiled: March 21, 2018Date of Patent: May 28, 2019Assignee: NeuroPace, Inc.Inventors: Rosana Esteller, Felice Sun
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Patent number: 10299729Abstract: This document describes heart rate detection with multi-use capacitive touch sensors. Fluctuations in capacitance are detected (802) using capacitive touch sensors. These capacitive touch sensors are also used to detect touch inputs to control operations of a computing device. When contact of a person's hand with the computing device is detected, the capacitive touch sensors produce raw capacitance data that indicates detected capacitance fluctuations. The raw capacitance data is extracted (902) from the capacitive touch sensors using a modified device driver that bypasses default driver configurations that ignore fluctuations in capacitance due to heartbeats. Times during which the person's hand contacts the computing device and locations of the contact are determined (804) from the raw capacitance data indicative of the fluctuations. The extracted raw capacitance data is then processed to determine the person's heart rate (806, 808).Type: GrantFiled: October 23, 2015Date of Patent: May 28, 2019Assignee: Google LLCInventors: Jingtao Wang, Shumin Zhai
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Patent number: 10299730Abstract: There is provided a physiological detection system including a physiological detection device and a host. The physiological detection device is configured to transmit a physiological data series to the host according to a local oscillation frequency. The host is configured to calculate a physiological value according to the physiological data series and determine a correction parameter according to a receiving data parameter and a reference data parameter, wherein the correction parameter is configured to correct the physiological value, process the physiological data series or adjust the local oscillation frequency of the physiological detection device.Type: GrantFiled: June 2, 2015Date of Patent: May 28, 2019Assignee: PIXART IMAGING INC.Inventors: Ren-Hau Gu, Chih-Hsin Lin, Yung-Chang Lin, Chien-Lung Liao
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Patent number: 10299731Abstract: An object pose measurement system based on MEMS IMU includes: an accelerometer, a magnetometer, a gyroscope, an object vector information calculation unit, and a rotation compensation unit; wherein the object vector information calculation unit is connected respectively to the accelerometer, magnetometer, gyroscope to receive respective measurement data and calculate object vector information; the rotation compensation unit is connected to the object vector information calculation unit to receive the object vector information, compute and output rotation compensated object vector information; wherein the rotation compensation unit performs quaternion rotation compensation computation and outputs the rotation compensated quaternion as the rotation compensated object vector information.Type: GrantFiled: May 4, 2017Date of Patent: May 28, 2019Assignee: National Tsing Hua UniversityInventors: Hsien-Ting Chang, Jen-Yuan Chang
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Patent number: 10299732Abstract: The disclosure extends to methods, devices, and systems for removing speckle from a coherent light source, such as laser light. The methods, devices, and systems help eliminate or reduce speckle introduced from a coherent light source, such as laser light, by utilizing the teachings and principles of the disclosure.Type: GrantFiled: March 14, 2014Date of Patent: May 28, 2019Assignee: DePuy Synthes Products, Inc.Inventors: Jeremiah D. Henley, Joshua D. Talbert, Laurent Blanquart, Donald M. Wichern
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Patent number: 10299733Abstract: Continuous Glucose Monitoring (CGM) devices provide glucose concentration measurements in the subcutaneous tissue with limited accuracy and precision. Therefore, CGM readings cannot be incorporated in a straightforward manner in outcome metrics of clinical trials e.g. aimed to assess new glycaemic-regulation therapies. To define those outcome metrics, frequent Blood Glucose (BG) reference measurements are still needed, with consequent relevant difficulties in outpatient settings. Here we propose a “retrofitting” algorithm that produces a quasi continuous time BG profile by simultaneously exploiting the high accuracy of available BG references (possibly very sparsely collected) and the high temporal resolution of CGM data (usually noisy and affected by significant bias).Type: GrantFiled: February 20, 2014Date of Patent: May 28, 2019Assignee: DexCom, Inc.Inventors: Claudio Cobelli, Simone Del Favero, Andrea Facchinetti, Giovanni Sparacino
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Patent number: 10299734Abstract: A system may include a photoplethysmograph (PPG) sensor configured to be secured to a patient and to generate a PPG signal for the patient. The system may also include a motion sensor configured to generate a motion signal indicative of motion of the patient. Further, the system may include a controller configured to receive the PPG signal from the PPG sensor and the motion signal from the motion sensor, to analyze the motion signal to detect motion of the patient, and to deactivate the at least one emitter of the PPG sensor based on the analysis of the motion signal when motion of the patient is detected.Type: GrantFiled: September 30, 2016Date of Patent: May 28, 2019Assignee: Covidien LPInventors: James N. Watson, Daniel Bartlett, Paul S. Addison
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Patent number: 10299735Abstract: A front-end system collects diagnostically relevant information or data, including pulse waveform information, and optionally timing information, symptom information, and/or diagnostic information. One or more sensors or transducers detect pulse waveforms in a consistent manner, across various subjects and practitioners. A back-end system stores diagnostically relevant information and diagnostic information, typically for a large population of subjects and practitioners. The back-end system generates system generated diagnoses and/or suggested remedial actions based on submitted inquiries or requests. The back-end system can advantageously employ machine learning techniques to identify correlations between defining characteristics or features of pulse waveforms and diagnoses, over a large number of samples submitted by a substantial number of practitioners, for instance of traditional Chinese medicine. The back-end system can also employ primary and/or secondary symptoms in identifying correlations.Type: GrantFiled: August 21, 2015Date of Patent: May 28, 2019Inventors: Thomas Adrian Furness, III, Ross Melville, Robert Doane, Brian Pal
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Patent number: 10299736Abstract: Methods, devices, and systems according to present principles provide ways to diagnose frailty and assess the severity of its clinical status—e.g., non-frail, pre-frail, and frail, especially as measured and quantified during activities of daily living. Systems and methods according to present principles objectively quantify physical activity behaviors and identify specific motor tasks, which indicate clinical frailty syndrome behaviors such as flopping, cautious-sitting, non-uniform walking fluctuations, cognitive decline, slowness, weakness, and exhaustion. Additionally, the systems and methods allow improved sensitivity and specificity of frailty identification by further assessing physiological parameters such as heart rate, respiration rate, and skin temperature in response to, or recovery from, specific activities.Type: GrantFiled: March 27, 2015Date of Patent: May 28, 2019Assignee: THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Bijan Najafi, Saman Parvaneh, Martha Jane Mohler, David G. Armstrong, Mindy Joy Fain, Marvin J. Slepian
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Patent number: 10299737Abstract: A method for diabetes care, the method (which also may be referred to as, involve or incorporate at least one of a tool, device or program) allowing for the characterization of the relevance of errors of parameters affecting glucose concentration on a postprandial glucose concentration outcome for a person with diabetes mellitusm, wherein the method involves at least one of sensing, determining, calculating, predicting, describing and communicating the effects of potential errors of parameters affecting glucose concentration on postprandial glucose concentration values within a clinically relevant glucose range.Type: GrantFiled: May 25, 2010Date of Patent: May 28, 2019Assignee: Roche Diabetes Care, IncInventors: Matthias Essenpreis, Michael Schoemaker, Sebastiaan La Bastide, Derek Brandt, Theodor Koschinsky, Sascha Heckermann
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Patent number: 10299738Abstract: Treatment of neurological injury through motor relearning. A game-based sensorimotor rehabilitator that enables individuals to interact with the functional objects using the appropriate amount of force, tilt, finger movement, and muscle activity to regain lost skill due to injury.Type: GrantFiled: November 16, 2015Date of Patent: May 28, 2019Assignee: NEW YORK UNIVERSITYInventors: Preeti Raghavan, Vikram Kapila
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Patent number: 10299739Abstract: A medical monitoring apparatus that monitors a status of a patient according to biological information of the patient includes a reliability evaluator 510 configured to obtain first biological information measured by a bedside monitor 200 and second biological information measured by a wearable sensor 300, and to evaluate a reliability of the second biological information according to a correlation between the first biological information and the second biological information, the first biological information and the second biological information belonging to an identical measurement item, and an alert determinator 600 configured to determine, using the first biological information and the second biological information, whether to issue an alert about an abnormality under a condition that depends on the reliability.Type: GrantFiled: December 6, 2017Date of Patent: May 28, 2019Assignee: Olympus CorporationInventor: Nobuyuki Watanabe
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Patent number: 10299740Abstract: Various methods and systems are provided for collision avoidance in cone-beam computed tomography (CT) systems. In one embodiment, a method for an imaging apparatus comprises calculating a likelihood of a collision between the imaging apparatus and a subject and/or its support based on a model of the subject, performing a scan of the subject responsive to the likelihood below a threshold, and not performing the scan otherwise. In this way, collisions between the patient and the imaging apparatus can be avoided.Type: GrantFiled: September 29, 2015Date of Patent: May 28, 2019Assignee: General Electric CompanyInventors: Thomas Mc Carthy, Yves Lucien Trousset
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Patent number: 10299741Abstract: Methods and systems are described for operating an imaging sensor, the imaging sensor including a multi-dimensional sensor. An electronic processor receives an output from the multi-dimensional sensor and transitions the imaging sensor from the low-power state into a ready state in response to a determination by the electronic processor, based on the output from the multi-dimensional sensor, that a first state transition criteria is satisfied and transitions the imaging sensor from the ready state into an armed state in response to a determination that a second state transition criteria is satisfied. In some implementations, the electronic processor operates the imaging sensor to capture image data only when operating in the armed state and prevents the imaging system from transitioning from the low-power state directly into the armed state.Type: GrantFiled: September 14, 2016Date of Patent: May 28, 2019Assignees: DENTAL IMAGING TECHNOLOGIES CORPORATION, TELEDYNE DALSA B.V.Inventors: Scott David Kravis, Leonid Khatutskiy, James Paul Frerichs, Adrian David French, Kyle Alan Pixton, Hein Loijens, Frank Polderdijk, Helmut Rosner
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Patent number: 10299742Abstract: Methods and systems are described for operating an imaging system that includes an intra-oral imaging sensor, an image sensing component, a multi-dimensional sensor, and an electronic processor. The intra-oral imaging sensor includes a housing and the image sensor component and the multi-dimensional sensor are at least partially housed within the housing. The multi-dimensional sensor includes a three-dimensional accelerometer, a three-dimensional gyroscope, and a three-dimensional magnetometer. The electronic processor is configured to execute one or more error condition check routines to determine whether an error condition is present based on an output received from the multi-dimensional sensor.Type: GrantFiled: June 19, 2017Date of Patent: May 28, 2019Assignee: DENTAL IMAGING TECHNOLOGIES CORPORATIONInventors: Scott David Kravis, Leonid Khatutskiy, James Paul Frerichs, Adrian David French, Kyle Alan Pixton
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Patent number: 10299743Abstract: According to some aspects, an x-ray apparatus for imaging and/or radiation therapy is provided, the x-ray apparatus comprises an electron source capable of generating electrons, at least one first target arranged to receive electrons from the electron source, the at least one first target comprising material that, in response to being irradiated by the electrons, emits broad spectrum x-ray radiation, at least one second target arranged to receive at least some of the broad spectrum x-ray radiation, the at least one second target comprising material that, in response to irradiation by broad spectrum x-ray radiation from the first target, emits monochromatic x-ray radiation, and at least one detector positioned to detect at least some of the monochromatic x-ray radiation emitted from the at least one second target.Type: GrantFiled: April 29, 2016Date of Patent: May 28, 2019Assignee: Imagine Scientific, Inc.Inventor: Eric H. Silver
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Patent number: 10299744Abstract: An x-ray detector comprises: a housing, including a cover removably fastened on a flange of a flanged base and forming a semi-hermetic seal therebetween, the flanged base including a bottom surface and the flange surrounding a perimeter of the bottom surface; and an x-ray imager positioned on the bottom surface, the x-ray imager including a scintillator and an image sensor, wherein the seal semi-hermetically encloses the x-ray imager in the housing, and is positioned nonadjacently to surfaces in contact with the x-ray imager. In this way, a simpler and less costly seal for a digital x-ray panel can be provide; furthermore, the seal is reusable and resealable, facilitating repair and refurbishment of the device.Type: GrantFiled: November 17, 2016Date of Patent: May 28, 2019Assignees: GENERAL ELECTRIC COMPANY, TELEDYNE DIGITAL IMAGING, INC., TELEDYNE DALSA B.V.Inventors: Biju Jacob, Brian David Yanoff, William Andrew Hennessy, Jeffery Jon Shaw, Douglas Albagli, Bartholomeus G. M. H. Dillen, Inge Peters, Anton Van Arendonk
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Patent number: 10299745Abstract: A traceable device and procedure suitable for investigating gastrointestinal motility disorders by measuring transit time of the device as it is passed through the gastrointestinal tract of a patient. The device includes a core material configured to be imaged with a gamma imaging process and optionally also an x-ray imaging process, and a sealing material substantially insoluble in gastrointestinal fluids and fully encapsulating the core material.Type: GrantFiled: December 28, 2015Date of Patent: May 28, 2019Assignee: Loyola University of ChicagoInventor: Robert Hans Wagner
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Patent number: 10299746Abstract: A radiation imaging apparatus provided with a detector capable of improving correction accuracy at a high counting rate. The present invention is provided with: grids that remove scattered beams that emanate from an object; and a plurality of detector sub-pixels arranged so as to divide the gap between the grids into three or more segments, wherein the area of each of the detector sub-pixels located below the wall surface of the grids is larger than that of each of the other detector sub-pixels in a planar view. The size of each of the detector sub-pixels not located below the wall surface of the grids is expressed as (Pg?Tg?Lsplit×2)/N, where Pg represents the pitch between the grids, Tg represents the thickness of each of the grids, and N represents the number of segments formed by the detector sub-pixels between the grids.Type: GrantFiled: December 21, 2016Date of Patent: May 28, 2019Assignee: Hitachi, Ltd.Inventors: Takafumi Ishitsu, Isao Takahashi, Kazuma Yokoi, Makoto Satou
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Patent number: 10299747Abstract: The disclosure provides a device having a C-arm, the C-arm including a main body of which the cross-sectional profile is formed as a double H, an outer wall, an inner wall and two side walls of the main body forming a rectangular cavity. The device also includes running wires arranged on the main body and running rollers, on which the C-arm is movably mounted, rolling on the running wires. The running wires and the running rollers are arranged in such a way that at least 50 percent of the mounting forces acting on the running wires due to the running rollers is introduced into the side walls of the main body. The disclosure also provides an x-ray imager having such a device. The disclosure offers the advantage that undesired oscillations of the C-arm are avoided.Type: GrantFiled: January 12, 2017Date of Patent: May 28, 2019Assignee: Siemens Healthcare GmbHInventors: Berthold Baumann, Ralf Gärtner, Michael Kleber, Thomas Kleber, Alexander Krämer, Harald Mulzer, Wolfgang Neuber, Matthias Schirbl, Josef Zeidler
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Patent number: 10299748Abstract: An X-ray device includes a camera to image an object and output the image of the object, a display member using a touch screen to display the image of the object output from the camera, and an X-ray irradiation region of the object, an X-ray irradiation region controller to control a region of the object to which an X-ray is irradiated, and a control member to enable the irradiation region controller to control the region of the object to which an X-ray is irradiated according to the X-ray irradiation region, when the X-ray irradiation region is determined, based on the image of the object displayed in the display member.Type: GrantFiled: August 24, 2018Date of Patent: May 28, 2019Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Byeong Won Lee, Jae Hwa Moon