Patents Issued in June 18, 2019
  • Patent number: 10322198
    Abstract: A liquid freshening composition is provided. The liquid freshening product includes about 0.5 wt. % to about 15 wt. % isopropyl myristate, by weight of the liquid freshening composition and greater than 40 wt. % of one or more perfume raw materials. The liquid freshening composition has a vapor pressure at 25° C. of about 0.03 Torr to about 1.0 Torr. The liquid freshening composition may be used with air freshening products having a delivery engine such as a wick, breathable membrane, gel, porous and semi-porous substrate, and combinations thereof.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: June 18, 2019
    Assignee: The Procter & Gamble Company
    Inventors: George Kavin Morgan, III, Stephen Jeffrey Blessing, Ronald David Turner
  • Patent number: 10322199
    Abstract: Technologies (e.g., devices, systems and methods) for sanitizing reservoirs of humidifiers are described. In some embodiments, the technologies include a sanitization gas system and a connector unit. The connector unit is configured to install into a portion (e.g., wall, bottom, top, or lid) of a reservoir, such as a reservoir of a humidifier. The connector unit includes an inlet passageway for supplying sanitizing gas (e.g., ozone) into the reservoir, and an outlet passageway for removing sanitizing gas from the reservoir. In some embodiments at least a portion of the outlet passageway is disposed radially around the inlet passageway. The sanitization gas system may provide a sanitizing gas to the inlet passageway and receive the sanitizing gas from the outlet passageway.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: June 18, 2019
    Assignee: SoClean, Inc.
    Inventor: Timothy Leyva
  • Patent number: 10322200
    Abstract: The present invention is a candle warming image display lamp (CWIDL) for use in displaying user selectable images while providing light such as to light a room brightly or as a night light, while also warming a preferably spill resistant wickless scented candle, without spilling hot molten candle wax.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: June 18, 2019
    Inventor: Michael R. Schramm
  • Patent number: 10322201
    Abstract: An assembly for evaporating a volatile material is described, the assembly comprising a device and a refill which are detachable from one another: wherein the device comprises a magnetic induction coil configured to operate with an alternating current passed therethrough at a frequency of between substantially 20 KHz to substantially 500 KHz and one or more volatile fluid emanation channels containing at least one piece of heat-conducting, non-magnetic metal foil and/or deposited heat-conducting, non-magnetic metal; and wherein the refill comprises at least one magnetic susceptor having a coercivity of substantially 50 ampere/meter (HC) to substantially 1500 ampere/meter (HC) and a substantially liquid-tight sealed reservoir containing the volatile material; wherein, in use, the magnetic susceptor(s) is arranged to heat the material predominately by magnetic hysteresis when the magnetic susceptor(s) is at least partially positioned in the induced magnetic field generated, in use, when said alternating current
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: June 18, 2019
    Assignee: RECKITT BENCKISER (BRANDS) LIMITED
    Inventor: Paul John Duffield
  • Patent number: 10322202
    Abstract: A microfluidic cartridge is provided. The microfluidic cartridge has a reservoir configured to contain a fluid composition. The microfluidic cartridge has a first face and a second face joined with the first face along a first edge. The second face comprises a second face outermost point in an X-direction. The microfluidic cartridge has a third face opposing the first face in a Z-axis and joined with the second face along a second edge. The microfluidic cartridge includes an electrical circuit having a first end portion disposed on the first face and a second end portion disposed on the second face. The microfluidic cartridge has a microfluidic die in electrical communication with the electrical circuit and in fluid communication with the reservoir. The microfluidic die is disposed on a region of the second face that is positioned inward from the second face outermost point in the X-direction.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: June 18, 2019
    Assignee: The Procter & Gamble Company
    Inventors: Dana Paul Gruenbacher, William Michael Cannon, James Daniel Anderson, Jr.
  • Patent number: 10322203
    Abstract: An apparatus for air flow generation for scent output is described. The device includes a scent system, a speaker, and an output channel. The scent system and the speaker share the output channel, and the speaker is to move air to release scent from the device. A membrane of the speaker may vibrate to produce the air flow.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: June 18, 2019
    Assignee: Intel Corporation
    Inventors: Mikko Kursula, Seppo Vesamaki, Matti A. Lahdenpera, Timo H. Nissinen, Marko Vaaranmaa
  • Patent number: 10322204
    Abstract: Provided herein is an ultraviolet sterilization and disinfection apparatus. One or multiple low-pressure ultraviolet lamps are arranged within the ultraviolet sterilization and disinfection apparatus. A configuration method therefor is such that the inner diameters of the low-pressure ultraviolet lamps are ?30-36 mm and the tube current density is: 0.250-0.800 A/cm2; alternatively the inner diameters are ?26-30 mm and the tube current density is: 0.280-0.850 A/cm2; alternatively, the inner diameters are ?20-26 mm and the tube current density is: 0.300-1.100 A/cm2; alternatively, the inner diameters are ?15-20 mm and the tube current density is: 0.340-1.350 A/cm2. The method allows the ultraviolet dosage of the ultraviolet sterilization and disinfection apparatus to be increased, thus increasing efficiency in sterilization and disinfection.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: June 18, 2019
    Inventor: Zhiming He
  • Patent number: 10322205
    Abstract: The present invention provides methods and systems for the flexible ion generation device includes at least one dielectric layer, at least one trace having a first end and a second end, the at least one trace is engaged to the at least one dielectric layer, and at least one emitter engaged to the trace for emitting ions.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: June 18, 2019
    Assignee: Global Plasma Solutions, Inc.
    Inventor: Charles Houston Waddell
  • Patent number: 10322206
    Abstract: The present invention relates, in part, to sutures which promote wound closure and/or healing. In particular, the present invention provides fibrin microthread sutures that mimic the mechanical behavior of a target tissue thereby reducing, for example, scarring, inflammation, and cell death at the ligature site, including monofilament sutures.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: June 18, 2019
    Assignee: Worcester Polytechnic Institute
    Inventors: George Pins, Glenn Gaudette, Adam Collette, William Edelman
  • Patent number: 10322207
    Abstract: An antiseptic composition for use as bone cement, in particular an antiseptic polymethylmethacrylate bone cement. The composition can be cured and comprises a pharmacologically tolerable salt of a monoperoxy dicarboxylic acid, whereby the salt of the monoperoxy dicarboxylic acid can be dissolved from the composition in the presence of water. Preferably, the salt of the monoperoxy dicarboxylic acid in the composition is used in the form of a powder, whereby the powder has a mean particle size of not more than 250 ?m. Preferably, the salt of the monoperoxy dicarboxylic acid, in solution at room temperature, is not degraded within 5 min by the catalase enzyme.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: June 18, 2019
    Assignee: HERAEUS MEDICAL GMBH
    Inventors: Sebastian Vogt, Lorena Calderón Ortiz
  • Patent number: 10322208
    Abstract: Techniques for modifying the surface of implantable devices, such as bioprosthetic valves, to improve the biocompatibility of the implantable devices are provided. In particular, a customizable, non-fouling surface coating may be formed on the surface of implantable devices that improves the biocompatibility of the implantable devices and has the potential to further reduce the occurrence of complications for patients of all ages. Additionally, various molecules of interest to specifically promote endothelialization of the implantable device may be added to the surface coating, which may facilitate the formation of an endothelial layer on the surface of the implantable device that would naturally maintain a non-thrombogenic, non-immunogenic environment in the long-term.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: June 18, 2019
    Assignee: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Monica Fahrenholtz, Kathryn Jane Grande-Allen
  • Patent number: 10322209
    Abstract: Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: June 18, 2019
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: David Knaack, John Winterbottom, David R. Kaes, Todd Boyce, Lawrence A. Shimp
  • Patent number: 10322210
    Abstract: The present invention relates to a preparation method for core-shell structured fibrous scaffolds, and more specifically to preparing a core part composition and a shell part composition that each have different constitutions by adding calcium phosphate cement and a protein, drug of combination thereof to alginate solution, and then inserting the above core part composition and shell part composition to internal and external nozzle of concentric nozzle respectively to inject into calcium ion aqueous solution and thereby hardening them, thus preparing core-shell structured rapidly setting Alg/?-TCP scaffolds capable of controllably releasing a protein or drug.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: June 18, 2019
    Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY
    Inventors: Hae-Won Kim, Roman Perez
  • Patent number: 10322211
    Abstract: Biphasic self-setting calcium phosphate (SSCP) used for bone graft material and dental material applications having shape formability, shape retentivity, and bone replacement properties in addition to biocompatibility, safety, non-infectiousness, and absence of outflow, wherein the work time for forming the shape of a kneaded material obtained by kneading biphasic SSCP powder and biphasic SSCP liquid is controlled. A method for controlling the work time for forming the shape of biphasic SSCP in which the moldable work time from the start of kneading to the setting of the kneaded material is adjusted to within a range of from 10 seconds to 600 seconds by kneading a biphasic SSCP powder and biphasic SSCP liquid, the biphasic SSCP powder comprising tetracalcium phosphate and ?-tricalcium phosphate and the biphasic SSCP liquid comprising a phosphoric acid aqueous solution containing a calcium component.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: June 18, 2019
    Assignees: MEDICAL U & A, INC., FRONTIER SCIENCE CORPORATION
    Inventor: Akiyoshi Sugawara
  • Patent number: 10322212
    Abstract: Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt thereof; and an effective amount of at least mepivacaine or a salt thereof are provided. The hyaluronic acid optionally has an average molecular weight ranging from 50,000 to 10,000,000 Daltons, and may be crosslinked hyaluronic acids, non-crosslinked hyaluronic acids, or a combination, in some embodiments. The compositions and methods of the present invention are useful for treating and preventing the cutaneous signs of chronological aging and/or induced by external factors such as stress, air pollution, tobacco or prolonged exposure to ultraviolet (UV) exposure, impaired surface appearance of the skin, impaired viscoelastic or biomechanical properties of the skin, and/or the long-lasting filling of volume defects of the skin.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: June 18, 2019
    Assignee: TEOXANE
    Inventors: Francois Bourdon, Stephane Meunier
  • Patent number: 10322213
    Abstract: Disclosed herein is the correlation of chemical properties of oils with the physical properties of a resulting cured oil composition. Also disclosed are biocompatible materials and coatings for medical devices prepared using enriched oils and methods for enhancing or modifying the physical and chemical characteristics of cured oils by enriching such oils with fatty acid alkyl esters. Methods of tailoring the properties of biocompatible materials and coatings to deliver one or more therapeutic agents are also provided.
    Type: Grant
    Filed: July 16, 2011
    Date of Patent: June 18, 2019
    Assignee: ATRIUM MEDICAL CORPORATION
    Inventors: Keith M. Faucher, Theresa K. Albergo, Paul Martakos
  • Patent number: 10322214
    Abstract: Biodegradable magnesium alloy implantable medical devices are protected to delay onset of corrosion, and thus biodegradability, or to corrode more uniformly. The protection allows for extended effective use of the devices while maintaining biodegradability. Examples of protective coatings include conversion coatings that at least partially remove exposed second phases from a surface of the magnesium alloy and coatings that provide a barrier between water and the surface of the magnesium alloy.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: June 18, 2019
    Assignee: Medtronic Vascular, Inc.
    Inventors: Syamala Rani Pulugurtha, Jeffrey Allen, James Mitchell, Christopher Storment, Jill Mendelson
  • Patent number: 10322215
    Abstract: Functionalized copolymers of isoolefins and conjugated diolefins, methods of preparing the copolymers, and their use as compatibilizers are disclosed. The diolefin monomer units of the co-polymer are modified at the C—C double bond along the backbone of the copolymer to include an oxygen containing functional group such as epoxide, ester or alcohol. The functionalized copolymers improve the wettability of a non-hydrophilic surface towards hydrophilic polymer and allows for the formation of homogenous layers of the hydrophilic polymers. In particular, the spreading of a hydrophilic polymer on a non-hydrophilic substrate is facilitated by applying the co-polymers as an interfacial layer between the two incompatible materials. The resulting coated substrates exhibit resistance to protein adsorption and cell growth after grafting. The co-polymers are especially suited in the coating of biomedical devices where a high degree of uniformity of the coated surface is required.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: June 18, 2019
    Assignees: LANXESS INTERNATIONAL SA, UNIVERSITY OF WESTERN ONTARIO
    Inventors: Goran Stojcevic, Gilles Arsenault, Elizabeth R. Gillies, Collin V. Bonduelle, Matthew J. McEachran
  • Patent number: 10322216
    Abstract: The present invention relates to a filtering device (8) for removing substances from blood or a blood component, the filtering device (8) comprising: a housing having an inlet and an outlet, at first sorbent material coupled with at least a first ligand located within the housing, and a second sorbent material coupled with at least a second ligand located within the housing, wherein the first ligand is for removing free hemoglobin (fHb) and the second ligand is for removing microvesicles (MV) from the blood or blood component passing through the filtering device (8), from the inlet to the outlet, wherein the first and second ligand are different from each other, and wherein the first and second sorbent material are the same or are different from each other.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: June 18, 2019
    Assignee: Fresenius Hemocare Italia S.R.L.
    Inventors: Giorgio Mari, Serena Borghi, Elena Finetti
  • Patent number: 10322217
    Abstract: An apparatus includes a tubular member defining a lumen and a channel, and a support member. The tubular member has a connection portion configured to be coupled to an organ wall. An outer edge of the connection portion is configured to contact a first portion of an inner surface of the wall when the connection portion is in an expanded configuration such that an interior volume of the organ is in fluid communication with the lumen. The support member is movably disposed within the channel and is configured to minimize movement of the wall relative to the tubular member. An end portion of the support member is disposed within the channel when the support member is in a first configuration. The end portion of the support member configured to contact a second portion of the inner surface of the wall when the support member is in a second configuration.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: June 18, 2019
    Assignee: HeartWare, Inc.
    Inventor: Paul A. Spence
  • Patent number: 10322218
    Abstract: An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: June 18, 2019
    Assignee: MAQUET CARDIOVASCULAR LLC
    Inventors: Walid N. Aboul-Hosn, William R. Kanz, Bruce A. Baker
  • Patent number: 10322219
    Abstract: The present invention relates to a method of determining the pressure or of a parameter correlated with the pressure in an extracorporeal circuit of a blood treatment apparatus, in particular of a dialyzer, wherein at least one blood pump which is driven by at least one motor is located in the blood circuit, wherein the motor current of the named motor and the blood flow or a parameter correlated therewith is measured for determining the pressure or the parameter correlated therewith and wherein the pressure p or the parameter correlated therewith is calculated from the measured values.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: June 18, 2019
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Alfred Gagel, Benedict Glaser, Haitham Ibrahim, Pascal Kopperschmidt
  • Patent number: 10322220
    Abstract: A method for extracorporeal blood treatment using a medical device including at least a dialyzer device, with the following steps: start of blood treatment by means of hemodialysis on the basis of default values for the hemodialysis; determination of current values or ratios of at least one blood flow, an ultrafiltration quantity, a substitution quantity or a type of substitution; recording of a therapy progress on the basis of an output signal of a sensor means; determination of a time of formation of a secondary membrane on the dialyzer by determination of a cross rate in the dialyzer device; change from the hemodialysis to a hemodiafiltration with post-dilution after a predetermined period of time has elapsed; and regulation of the substitution quantity during hemodiafiltration with post-dilution. Corresponding tools for carrying out the method are arranged in a device for extracorporeal blood treatment.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: June 18, 2019
    Assignee: B. Braun Avitum AG
    Inventor: Heiko Riemenschneider
  • Patent number: 10322221
    Abstract: A method of reducing the concentration of carbon dioxide in blood plasma includes removing blood from a patient and treating or processing at least blood plasma of the blood by flowing the blood plasma on one side of at least one semi-permeable membrane and flowing a dialysate on the other side of the at least one semi-permeable membrane. The dialysate has a concentration of bicarbonate less than the concentration of bicarbonate in the blood plasma before treating the blood plasma and has a composition such that the blood plasma strong ion difference that results from treating the blood plasma in conjunction with an achieved reduction in blood plasma CO2 concentration results in a blood plasma pH that does not change by more than +/?0.5 during treatment.
    Type: Grant
    Filed: January 18, 2014
    Date of Patent: June 18, 2019
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: John Alston Kellum, Jr., Matthew Cove, William J. Federspiel
  • Patent number: 10322222
    Abstract: Extracorporeal circuit devices that can be used for on-pump open-heart surgery to support surgical procedures such as coronary artery bypass grafting are described. In some embodiments, an oxygenator can include an integral pump. Such an integrated arrangement can advantageously provide an extracorporeal circuit with a lower overall volume than other conventional extracorporeal circuits.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: June 18, 2019
    Assignee: Terumo Cardiovascular Systems Corporation
    Inventors: Louis F. Peticca, Christine T. Cordaro
  • Patent number: 10322223
    Abstract: An oxygenator comprising a hollow-fibre film bundle is surrounded at least in certain areas by a bubble-retaining filter. In order to ensure an optimal function of the hollow-fibre film bundle and the bubble-retaining filter, it is proposed that a gas-permeable retaining structure is arranged between hollow-fibre film bundle and bubble-retaining filter.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: June 18, 2019
    Assignee: MEDOS Medizintechnik AG
    Inventors: Wolfgang Ochel, Andreas Maurer
  • Patent number: 10322224
    Abstract: An apparatus for performing peritoneal dialysis includes a housing; a peritoneal dialysis supply bag supported by and/or located above the housing; a first valve for controlling gravity flow of fresh peritoneal dialysis fluid from the supply bag to a patient; a second valve for controlling gravity flow of used peritoneal dialysis fluid from the patient to a drain; and a pressure sensor positioned and arranged with respect to the gravity flow of fresh peritoneal dialysis fluid or the gravity flow of used peritoneal dialysis fluid to provide a reading used to evaluate a head height pressure.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: June 18, 2019
    Assignee: BAXTER INTERNATIONAL INC.
    Inventors: Robert Warren Childers, Vital Eerlingen, Patrick Balteau, Duane Belongie
  • Patent number: 10322225
    Abstract: According to at least one example embodiment, a system of monitoring blood leaks during hemodialysis therapy includes a wetness sensing device and a hemodialysis machine. The wetness sensing device is configured to transmit information wirelessly, the information being indicative of an absence of a liquid or a presence of a liquid. The hemodialysis machine includes, or is coupled to, a wireless receiver having two or more antennas. Signals received at the two or more antennas are decoded at the wireless receiver. If decoded signals indicate a detected wetness, the hemodialysis machine is caused to halt blood flow in and out of the machine and generate an alarm.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: June 18, 2019
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Michael Emmanuel Kotsos, Alexander J. Brown, Roland Levin, Fei Wang, Donovan Halliburton
  • Patent number: 10322226
    Abstract: Methods for clearing of fecal matter the wall of a colon or other body lumen for diagnostic inspection, the methods being adapted to clearing of fecal matter comprised of particles of various sizes and compositions. Methods are further adapted for application in patients who have undergone a restricted scope of preparation to reduce and/or remediate the particle structure of colon contents, or no preparation at all, before diagnostic inspection.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: June 18, 2019
    Assignee: Motus GI Medical Technologies Ltd.
    Inventors: Noam Hassidov, Eyal Kochavi, Tzach Arnon, Kobi Luleko
  • Patent number: 10322227
    Abstract: A kit of components for a medical infusion includes a syringe having a syringe body with a liquid chamber having a volumetric capacity in a range of 5 ml to 30 ml, large bore tubing having an inner diameter greater than 3 mm and less than or equal to 6 mm and a length in a range of 4 feet to 10 feet, a valve with an axially extending valve body with opposing first and second ends, and a package holding the syringe pre-attached to the valve body and the large bore tubing in a sterile condition to thereby provide components in a ready-to-use configuration for insertion of the syringe and valve into an infusion device. The valve body includes an inlet tube residing between the first and second ends of the valve body and an exit port on the first end of the valve body.
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: June 18, 2019
    Assignee: 410 Medical, Inc.
    Inventors: Mark D. Piehl, Galen C. Robertson, John Tyler Willis Hagler, Robert W. Titkemeyer, Frederic C. Feiler, Jr.
  • Patent number: 10322228
    Abstract: A power injector is disclosed having power injector control logic, which in turn includes a decay constant cross-reference, for instance in the form of a data structure. Flow rate decay constant information may be stored by the decay constant cross-reference. A decay constant, which may be used by the power injector to generate an exponentially decaying flow rate for an injection, may be stored in the decay constant cross-reference in conjunction with a particular imaging unit. The decay constant cross-reference may be searched by entering a model or module number of an imaging unit to identify the corresponding flow rate decay constant to be used by the power injector.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: June 18, 2019
    Assignee: Liebel-Flarsheim Company LLC
    Inventors: Frank M. Fago, Alya Schalabi
  • Patent number: 10322229
    Abstract: An infusion pump assembly includes a reservoir assembly configured to contain an infusible fluid. A motor assembly is configured to act upon the reservoir assembly and dispense at least a portion of the infusible fluid contained within the reservoir assembly. Processing logic is configured to control the motor assembly. The processing logic includes a primary microprocessor configured to execute one or more primary applications written in a first computer language; and a safety microprocessor configured to execute one or more safety applications written in a second computer language.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: June 18, 2019
    Assignee: DEKA PRODUCTS LIMITED PARTNERSHIP
    Inventors: Geoffrey P. Spencer, Robert J. Bryant
  • Patent number: 10322230
    Abstract: A patency device for catheter assemblies and other elongate tubular devices used for establishing access to an interior body portion of a patient is disclosed. The patency device establishes and preserves patency of one or more lumens defined by the catheter assembly by providing impulses of positive pressure to fluid disposed in the lumen of the catheter assembly. In one embodiment, the patency device comprises a fluid reservoir configured to provide a fluid path to at least one lumen of the catheter assembly, and a pressure input portion. The pressure input portion is configured to provide pressure for one or more impulses of positive pressure to a fluid disposed within the lumen. The impulses are configured to dislodge occlusions that may have formed in the lumen. A negative pressure can then be provided to the lumen to aspirate the occlusion.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: June 18, 2019
    Assignee: C. R. Bard, Inc.
    Inventors: Gidon Ofek, Jay A. Muse, Bret Hamatake, Garrick T. Smith
  • Patent number: 10322231
    Abstract: A drive mechanism includes a housing, a piston adapted to impart movement to a plunger seal within a drug container, a plurality of biasing members disposed in parallel, and a retainer. The biasing members are disposed to release energy to cause movement of the piston from a retracted first position to the extended second position, the piston bearing against the plunger seal to dispense medicine. The retainer is disposed to maintain the biasing members in the energized position and to release the biasing members to permit the piston to dispense the medicine. The drive mechanism may also include an end-of-dose indicator to identify at least one of when the sleeve assembly is disposed subjacent a window in the housing, the relative motion of the sleeve assembly with reference to the window or another reference component, the stoppage of such motion, and the rated or change of rate of motion.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: June 18, 2019
    Assignee: UNL Holdings
    Inventors: Ryan M. Agard, Ian B. Hanson, Nicholas J. Ciccarelli, Sean M. O'Connor, Kevin Bokelman, Paul F. Bente, IV
  • Patent number: 10322232
    Abstract: The present invention provides a regulator for medicine infusion capable of preventing a flow rate of a liquid medicine to be injected to a patient from exceeding a predetermined flow rate needed for a patient, and controlling the flow rate of the liquid medicine to be uniformly maintained. The regulator for medicine infusion of the present invention provides the advantages of blocking and continuing the inflow of the liquid medicine by the combination of the elements of the membrane member, the resilient plate and the lever and by the adjusted resilience of the resilient plate, and allowing the liquid medicine to flow at a constant rate by adjusting the resilience of the resilient plate and/or the resilience of the membrane member at predetermined levels.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: June 18, 2019
    Inventor: Young Mu Kim
  • Patent number: 10322233
    Abstract: A medical device includes a first housing portion (FHP) and a second housing portion (SHP) configured to be to be movable relative to each other from a first position to operatively engage at a second position to couple at least one of a drive device and a needle-inserting device supported by one of the FHP and the SHP to a reservoir supported by the other of the FHP and the SHP. Electronic circuitry configured to detect at least one of a first magnetic interaction between a magnet and at least one of a first magnetically attractive material and a first magnet-responsive device and a second magnetic interaction between the magnet and at least one of a second magnetically attractive material and a second magnet-responsive device, and to provide a signal or a change in state in response to detecting at least one of the interactions.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: June 18, 2019
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Ian B. Hanson, Paul F. Bente, IV
  • Patent number: 10322234
    Abstract: The invention relates to an Apparatus, especially a delivery device, comprising a housing (4100), a retainer (4200, 4200?) for holding a cartridge (4220, 4220?), a cover part (4240, 4240?) for accessing the retainer (4200, 4200?), the cover part (4240, 4240?) being moveable relative to the housing (4100) between an open and a closed position, wherein the apparatus further comprises cover part biasing means for exerting a biasing force onto the cover part (4240, 4240?) in the closed position to bias the cover part (4240, 4240?) inwardly and/or distally against the housing (4100).
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: June 18, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Neal Alexander Blundred, Aled Meredydd James
  • Patent number: 10322235
    Abstract: A plurality of embodiments of mixing syringes are provided. Inventive key to all of the embodiments is a piston valve which divides a barrel to create a pair of chambers in which matter and liquid can be disparately and securely disposed before mixing. Each disclosed piston valve is actuated by force on an associated plunger rod which produces pressure within an associated syringe resulting in a change of the valve state from closed to open. In addition, each such valve comprises check valve action which is permissive to only distal flow through the syringe. Embodiments for both a basic mixing syringe and a mixing syringe with flush are disclosed. Considerations and methods for chamber filling without valve actuation are provided. A mixing syringe system with flush system utilizing a dual chamber syringe having a male luer fitting and a separate diluent containing vessel having a female luer fitting is also disclosed.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: June 18, 2019
    Assignee: THORNE CONSULTING & INTELLECTUAL PROPERTY, LLC
    Inventors: Gale Harrison Thorne, Jr., Kendall Patterick Thorne, Gale Harrison Thorne, Sr.
  • Patent number: 10322236
    Abstract: Described herein are syringe devices, systems and methods. In general, the syringe may include a first chamber and a cartridge movable within the first chamber. The cartridge may include a cartridge chamber and a valve in fluid communication with the cartridge chamber and the first chamber and having an open configuration and a closed configuration. The valve may allow movement of a liquid out of the cartridge chamber while in a open configuration. The cartridge may also include a second end, movable within the cartridge chamber, and a locking mechanism having a locked configuration and an unlocked configuration, the locking mechanism preventing movement of the second end within the cartridge chamber while in the locked configuration.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: June 18, 2019
    Assignee: Bee Sight Limited
    Inventors: Martin N. Lee, Jeffrey J. Christian, Michael D. Laufer, Geoffrey H. Willis
  • Patent number: 10322237
    Abstract: An autoinjector having a reservoir containing fluid and including: a piston; a piston rod cooperating with the piston and is movable between a rest position and an injection position in which the piston rod has moved the piston to inject the fluid; an actuator spring urging the piston rod towards its injection position; a force-adjustment system exerting at least one force on the piston rod, the force adding to the force exerted by the spring on the piston rod at the beginning of injection; two pivot members cooperating with the piston rod and are connected together by two resilient elements, at least one pivot member being blocked prior to actuation by a locking system, thus preventing the autoinjector from being actuated, and an unlocking element adapted to move and/or to deform the locking system so as to unblock the at least one pivot member.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: June 18, 2019
    Assignee: APTAR FRANCE SAS
    Inventor: David Fabien
  • Patent number: 10322238
    Abstract: A needle-free injection device suitable for delivering a therapeutic substance into the intradermal space of a patient. The needle-free injection device includes an injector body defining a syringe end. The device also includes a first handle attached with a hinge to the injector body such that the first handle pivots between an open and a closed position and remains attached to the injector body during an injection, a main spring positioned within the injector body, a return sleeve engaged with the main spring, and a first linkage between the first handle and the return sleeve. The first linkage causes the return sleeve to move away from the syringe end of the injector body when the first handle is moved from the open position to the closed position, thereby compressing the main spring. Needle-free injection systems and methods of operating a needle-free injection device are also disclosed.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: June 18, 2019
    Assignee: PharmaJet, Inc.
    Inventors: Chris Cappello, Matt Wixey, John W. Bingham
  • Patent number: 10322239
    Abstract: Medicament delivery devices for administration of opioid antagonists are described herein. In some embodiments, an apparatus includes a housing, a medicament container disposed within the housing and an energy storage member disposed within the housing. The medicament container is filled with a naloxone composition that includes naloxone or salts thereof, a tonicity-adjusting agent, and a pH-adjusting agent, whereby the osmolality of the naloxone composition ranges from about 250-350 mOsm and the pH ranges from about 3-5. The energy storage member is configured to produce a force to deliver the naloxone composition.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: June 18, 2019
    Assignee: kaleo, Inc.
    Inventors: Eric S. Edwards, Evan T. Edwards, Mark J. Licata, Paul F. Meyers, Frank E. Blondino
  • Patent number: 10322240
    Abstract: A medicament delivery device includes a proximal sub-assembly and a distal sub-assembly configured to be connected to each other. The proximal sub-assembly includes a key member, and the distal sub-assembly includes a power pack unit having a lock mechanism for locking the power pack unit such that unintentional activation of the power pack unit during transportation is avoided. The key member is configured to interact with the lock mechanism during assembling of the proximal and distal sub-assemblies such that the lock mechanism is released.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: June 18, 2019
    Assignee: SHL Medical AG
    Inventor: Stefan Morén
  • Patent number: 10322241
    Abstract: Injection systems with storage compartments to house various materials are described. The storage compartments facilitate provision of medical care in space- and time-efficient manners and are particularly useful in providing care in non-medical facilities.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: June 18, 2019
    Assignee: Hyprotek, Inc.
    Inventor: Patrick O. Tennican
  • Patent number: 10322242
    Abstract: The mechanism includes a body defining an axial direction, a dial that is moved for setting a dose, an indicator member coupled with the dial, and a movable window displaying a surface area of the indicator member. The indicator member is axially moved relative to the body.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: June 18, 2019
    Assignee: Sanofi
    Inventors: Simon Lewis Bilton, Michael Bainton, William Marsh, Matthew Jones
  • Patent number: 10322243
    Abstract: A dose setting mechanism for a medicament delivery device is presented having a locking assembly that reliably and consistently unlocks a dose injection button and concurrently a lead screw when the dose setting mechanism is transitioned from a non-activated state to an activated state. This locking assembly uses a rotating plate having a locking protrusion that engages a radial projecting tab on a rotationally fixed plunger rod nut. An alignment member is also presented that prevents rotational drift of a dosing member.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: June 18, 2019
    Assignee: SHL GROUP AB
    Inventors: Lucio Giambattista, Antonio Bendek, Ling-Hsiang Chao
  • Patent number: 10322244
    Abstract: A dose setting mechanism for a medicament delivery device is presented having a locking assembly that reliably and consistently unlocks a dose injection button and concurrently a lead screw when the dose setting mechanism is transitioned from a non-activated state to an activated state. This locking assembly uses a rotating plate having a locking protrusion that engages a radial projecting tab on a rotationally fixed plunger rod nut. An alignment member is also presented that prevents rotational drift of a dosing member.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: June 18, 2019
    Assignee: SHL GROUP AB
    Inventors: Lucio Giambattista, Antonio Bendek, Ling-Hsiang Chao
  • Patent number: 10322245
    Abstract: The present invention relates to a medicament delivery device comprising a generally tubular distal housing part (10; 110) having opposite proximal and distal ends, wherein third mechanically coded interface means (11; 111) are arranged on its proximal end; a generally tubular proximal housing (20; 120) part having opposite proximal and distal ends and being releasibly connected to said distal housing part, wherein with fourth mechanically coded interface means (22; 122) are arranged on its distal end; a medicament container having a slidable stopper, wherein said container is arranged to be positioned within said proximal housing part; a plunger rod (60; 160) arranged within said distal housing; drive means arranged within said distal housing and being operably connected to said plunger rod for driving said plunger rod and thereby said stopper towards the proximal end of the device; wherein said device further comprises an interface member (50; 150) comprising first (51; 151) and second (52; 152) mechanicall
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: June 18, 2019
    Assignee: SHL MEDICAL AG
    Inventors: Lennart Brunnberg, Anders Wieselblad, Jonas Norebring
  • Patent number: 10322246
    Abstract: An injection device has a housing in which a syringe can be received that has an injection needle, a receiving chamber, a piston and a piston ram, and a control arrangement for controlled actuation of the syringe during an application procedure that includes at least one puncture stroke, one injection stroke and one return stroke. The control arrangement has an actuation element for applying a drive force to a syringe holder which is movable relative to the housing and on which the receiving chamber can be secured, a ram holder which is movable relative to the housing and on which the piston ram can be secured, and a transmission mechanism by means of which the ram holder can be coupled to the actuation element. Provision is made that the transmission mechanism has a toothed gearing by means of which the ram holder can be driven, according to a relative movement of the actuation element with respect to the housing, and which for this purpose has teeth on the housing.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: June 18, 2019
    Assignee: H & B ELECTRONIC GMBH & CO. KG
    Inventors: Tobias Morlok, Wilfried Weber
  • Patent number: 10322247
    Abstract: A swiveling intravenous therapy tubing connection system for easy rotational adjustment of an intravenous tubing line between a sterile container and a catheter used to administer a fluid to a patient features the sterile container which is a sterile intravenous fluid container and the catheter which is an intravenous therapy catheter located in the patient. The system features a length of intravenous therapy tubing having a female quick-connect swivel tubing connector located on a tubing first end and a quick-connect double swivel tubing connector located on a tubing second end. The female quick-connect swivel tubing connector is rotationally connected to a first mated male swivel tubing connector located on an intravenous fluid outlet of the intravenous fluid container. The quick-connect double swivel tubing connector is rotationally connected to a second mated male swivel tubing connector located on an intravenous fluid inlet of the catheter.
    Type: Grant
    Filed: October 1, 2015
    Date of Patent: June 18, 2019
    Inventor: John C. Radcliffe, Jr.