Abstract: A hybridoma cell line of secreting clarithromycin monoclonal antibodies with a preservation number of hybridoma cell line of CGMCC No. 14696 belongs to the field of food safety immunological detection. BALB/c mice are immunized through one time immunization with complete freund's adjuvant, three times of booster immunization with incomplete freund's adjuvant and one time of rush immunization with clarithromycin complete antigen without adjuvant; the spleen cells from BALB/C mice immunized with high potency and low value of IC50 are fused with murine myeloma cells; and then the hybridoma cell line is obtained through indirect competitive ELISA screening and three subclones. The monoclonal antibody secreted by this cell line has good specificity and detection sensitivity to clarithromycin (value of IC50 is 0.3 ng/ml), being suitable for detection of clarithromycin in food.

Abstract: The present invention relates to engineered IgG Fc constructs and uses thereof.

Abstract: Disclosed are a bifunctional peptide having the capability to permeate cells and the capability to regenerate muscles and the use thereof. Advantageously, the bifunctional peptide has a function of regenerating muscle cells and thus is useful for the prevention or treatment of diseases affecting muscle regeneration, and additionally has the capability to permeate cells and thus eliminates the necessity to adhere an additional peptide or add other agent or drug for cell permeation of the peptide, thereby finally exerting an efficient muscle generation effect. Thus, the bifunctional peptide can be easily applied to various surgical regenerative treatments and can shorten the treatment period.

Abstract: Fungal crosslinked structures, fungal crosslinking systems, and methods for crosslinking a fungal material. The crosslinked fungal material described herein comprises a variety of crosslinkers, crosslinking sites, and various combinations of crosslinks, each forming unique structures. The crosslinked fungal material comprises at least one crosslinking compound attached to a bonding site. The fungal crosslinking system includes a preparation unit, an impregnating unit, a crosslinking unit and a rinsing unit. The preparation unit may partially deacetylate chitin within the fungal material and within chitin nanowhiskers. The impregnating unit impregnates the fungal material with chitin nanowhiskers. The crosslinking unit is configured to crosslink the fungal material and chitin nanowhiskers via genipin to create a composite material. The rinsing unit rinses and removes unreacted genipin material thereby rendering a crosslinked composite material.

Abstract: The present application provides an improved process for the preparation of sugammadex by reacting a salt of 3-mercapto propionic acid with 6-per-deoxy-6-per-halo-?-cyclodextrin in a suitable organic solvent. This application also provides crystalline form of a salt of 3-mercapto propionic acid, preferably di sodium salt of 3-mercapto propionic acid and its use for the preparation of sugammadex, whereas formula (I) shows the sodium salt of sugammadex.

Abstract: Provided herein are organic solvent-based processes for the removal of rubber from aged briquettes made from compressed plant matter (briquettes) of non-Hevea plants.

Abstract: A polymerization catalyst supply system is provided. The polymerization catalyst supply system can be used to prepare polyolefin polymers with multimodal or broad molecular weight distribution, or to prepare polyolefins having broad compositional distribution. A process for preparing polyolefin polymers using the polymerization catalyst supply system is also provided.

Abstract: The present disclosure provides methods for producing an olefin polymer by contacting a C3-C40 olefin, ethylene and a diene with a catalyst system including an activator and a metallocene catalyst compound comprising a substituted or unsubstituted indacenyl group and obtaining a C3-C40 olefin-ethylene-diene terpolymer typically comprising from 1 to 35 mol % of ethylene, from 98.9 to 65 mol % C3-C40 olefin, and, optionally, from 0.1 to 10 mol % diene. Preferably, a propylene-ethylene-ethylidene norbornene is obtained.

Abstract: A mixed metallocene catalyst system can comprise at least one metallocene catalyst compound comprising a structure represented by formula (A) below and optionally at least one other metallocene catalyst compound having a structure represented by formula (B) below: A mixed metallocene catalyst system can additionally include a non-coordinating anion type activator comprising a supported alumoxane or aluminum alkyl, and optionally a scavenger. A process for making a polymeric product can comprise: contacting a C2-C22 alpha-olefin feed with the catalyst system to obtain a polymerization reaction mixture; and obtaining a polymer product from the polymerization reaction mixture. A polymer product can be made by the process.

Abstract: The present invention relates to a novel process for preparing high-reactivity isobutene homo- or copolymers with a content of terminal vinylidene double bonds per polyisobutene chain end of at least 70 mol %. The present invention further relates to novel isobutene polymers.

Abstract: Provided herein are polyolefin dispersants, as well as methods for producing polyolefin dispersants. The polyolefin dispersants can be defined by the formula below where Rx is cationic initiator residue; Ra is a polyolefin group; R1 and R2 are each, independently in each —(CR1R2) unit, H, alkyl, alkoxy, or alkylaryl; R3 and R4 are each, independently, H, alkyl, or alkoxy; m is an integer from 1 to 20; n is an integer from 1 to 6; r is an integer from 1 to 4; Y is a polyvalent amine linker comprising one or more tertiary amines, wherein the polyvalent amine linker does not include a primary amine or a secondary amine; and A is absent, or comprises a dispersive moiety.

Abstract: Disclosed herein are ethylene-based polymers generally characterized by a density of at least 0.94 g/cm3, a high load melt index from 4 to 20 g/10 min, a zero-shear viscosity at 190° C. from 20,000 to 400,000 kPa-sec, and a relaxation time at 190° C. from 225 to 3000 sec. These ethylene polymers can be produced by peroxide-treating a broad molecular weight distribution Ziegler-catalyzed resin, and can be used in large diameter, thick wall pipes and other end-use applications.

Abstract: A catalyst component for the polymerization of olefins, comprising Ti, Mg, halogen, an electron donor (ID) selected from the group consisting of aliphatic cyclic ethers and alkyl esters of aliphatic monocarboxylic acids and a compound of a metal selected from the group consisting of Zn and Cu, wherein the catalyst component is devoid of Zn—C or Cu—C bonds and the Mg/Ti molar ratio ranges from 4.0 to 50.0.

Abstract: The present disclosure provides an olefin polymer having excellent film processability and physical properties, and a preparation method of the same.

Abstract: The present disclosure provides methods for producing an olefin polymer by contacting a C3-C40 olefin, ethylene and a diene with a catalyst system including an activator and a metallocene catalyst compound comprising a substituted or unsubstituted indacenyl group and obtaining a C3-C40 olefin-ethylene-diene terpolymer typically comprising from 30 to 55 mol % ethylene, from 69.09 to 45 mol % C3 to C40 comonomer, and from 0.01 to 7 mol % diene wherein the Tg of the terpolymer is ?28° C. or less. Preferably, a propylene-ethylene-ethylidene norbornene is obtained.

Abstract: This invention relates to production of propylene-predominant copolymers using a transition metal complex and at least two different non-coordinating anion activators. An olefinic feed comprising a C3-C40 alpha olefin, ethylene, and a diene monomer is contacted under polymerization reaction conditions with a catalyst system comprising a first non-coordinating anion activator, a second non-coordinating borate activator differing from the first non-coordinating anion activator, and a transition metal complex comprising a tetrahydro-s-indacenyl or tetrahydro-as-indacenyl group bound to a group 3-6 transition metal. A molar ratio of the first non-coordinating anion activator to the second non-coordinating anion activator is sufficient to produce a melt flow rate under the polymerization reaction conditions for the resulting copolymer of about 30 g/10 min or below as determined by ASTM D-1238 (230° C., 2.16 kg).

Abstract: Fluorescent resin particles which comprise a water-soluble fluorescent dye and a polymer made from a monomer mixture.

Abstract: The invention provides methods for preparing a polymer-grafted and functionalized nonwoven membrane adapted for use in separation processes. The invention further provides so-formed membranes as well as improved separation methods utilizing the membranes. The polymer-grafted and functionalized nonwoven membranes are particularly formed utilizing thermal grafting. In particular, an acrylate or methacrylate polymer can be grafted onto a nonwoven web comprising a plurality of polymeric fibers to form a plurality of polymer segments covalently attached to the polymeric fibers. Thermal grafting particularly can comprise using a thermal initiator and exposing the nonwoven web to heat to initiate polymerization of the acrylate or methacrylate monomer. The grafted polymeric fibers can be functionalized to attach at least one functional group adapted for binding to a target molecule to the polymer segments of the grafted polymeric fibers.

Abstract: This invention relates to polymer polyols comprising the free-radical polymerization product of a base polyol, at least one ethylenically unsaturated monomer, and, optionally, a preformed stabilizer, in the presence of at least one free-radical polymerization initiator and at least one chain transfer agent, in which the base polyol is a polyether carbonate polyol. A process for preparing these polymer polyols is also described. This invention also relates to a polyurethane foam prepared from these polymer polyols and to a process for the preparation of these polyurethane foams.

Abstract: The synthesis and characterization of phenol-glycol cross-linked polymers are reported. The polymers have high affinity for toxic metal ions such as mercury (II) and can be utilized in methods of analyzing the content of toxic metal ions in a sample and the removal of toxic metal ions from aqueous solutions.

Abstract: A polymerizable composition for optical materials of the present invention includes a polymer (a) comprised of one or more compounds selected from compounds represented by the following General Formulas (1) to (4), a compound (b) of which light absorption characteristics vary by sensing changes in environment; and a polymerization reactive compound (c) (except for the polymer (a)).

Abstract: Aqueous polyurethane dispersions, prepolymers for formation of these dispersions, methods for their use in shaping articles, as well as shaping articles produced thereby are provided.

Abstract: The present disclosure is drawn to a reactive polyurethane dispersion including a polymer strand having a polymer backbone that has two ends terminating at a first capping unit and a second capping unit. The polymer backbone can include polymerized monomers including a reactive diol and a diisocyanate. The reactive diol can be an acrylate-containing diol, a methacrylate-containing diol, or combination thereof. The first capping unit can be an acrylate-containing monoalcohol or a methacrylate-containing monoalcohol reacted with an isocyanate group of the diisocyanate. The second capping unit can be 3-(cyclohexylamino)-1-propanesulfonic acid or 2-(cyclohexylamino)ethanesulfonic acid reacted with an isocyanate group of the diisocyanate.

Abstract: The present technology provides a one-part moisture-curable polyurethane composition excellent in long-term adhesion against weather resistance and vibration. According to the embodiment of the present technology, a one-part moisture-curable polyurethane composition includes: a urethane prepolymer having an isocyanate group; a morpholine compound having one morpholine ring; and an ether compound having two dimethylamino groups.

Abstract: The present technology provides a polyurethane composition including: a main agent; and a curing agent, wherein the main agent includes a urethane prepolymer having an isocyanate group, a morpholine compound having one morpholine ring, and an ether compound having two dimethylamino groups, and the curing agent includes an active hydrogen compound having two or more active hydrogen-containing groups in one molecule.

Abstract: The invention relates to a thermoplastic polyurethane matrix resin composition, comprising at least one C3-8 alkane diol, at least one alkoxylated aromatic diol and at least one polyisocyanate. Furthermore, the present invention relates to a fiber-reinforced composite comprising a cured thermoplastic polyurethane polymer matrix according to the present invention and a fiber material. Moreover, a method for the manufacture of the fiber-reinforced composite according to the present invention and use of the composition or the fiber-reinforced composite in railway vehicles, automotive vehicles, aircraft vehicles, boats, space vehicles, motorbikes, bicycles, sporting goods, helmets, functional clothing, shoes, construction parts in bridges and buildings or wind turbine blades are described.

Abstract: A method of forming a flexible polyurethane foam that passes BS 5852:2006 source V (Crib 5) test. The method includes providing a modified polyisocyanate polyaddition (PIPA) 5 polyol formed by contacting a PIPA polyol dispersion with at least one carboxylic acid having a melting point above zero degree Celsius and present in a carrier solvent. The PIPA polyol dispersion has a polyol liquid phase content of 60 wt. % to 90 wt. % and a solid particle phase content of 10 wt. % to 40 wt. % based on a total weight of the PIPA polyol dispersion. From 10 weight percent (wt. %) to 80 wt. % of the modified PIPA polyol is combined with 90 wt. % to 20 10 wt. % of at least another polyether polyol based on a total weight of a polyol blend of the PIPA polyol and the at least another polyether polyol, where the polyether polyol is formed with propylene oxide and ethylene oxide and has an equivalent weight of 1,000 to 2,000 and a functionality of 3 to 6.

Abstract: Provided is a polyisocyanate mixture including: a triisocyanate compound (A) represented by Formula (I); and polyisocyanate (B) obtained from at least one diisocyanate selected from the group consisting of aliphatic diisocyanate, alicyclic diisocyanate, and aromatic diisocyanate. (In Formula (1), a plurality of Y1's each independently represent a single bond or a divalent hydrocarbon group having 1 to 20 carbon atoms which may have an ester structure and/or an ether structure. A plurality of Y1's may be the same as or different from one another. R1 represents a hydrogen atom or a monovalent hydrocarbon group having 1 to 12 carbon atoms.

Abstract: An epoxy resin, comprising an epoxy compound having a mesogen structure, wherein, when performing a process of decreasing a temperature of the epoxy resin from 150° C. to 30° C. at a rate of 2° C./min, and a process of increasing the temperature of the epoxy resin from 30° C. to 150° C. at a rate of 2° C./min, in this order, the epoxy resin has a maximum value of ??2/??1 of 20 or less within a temperature range of from 30° C. to 150° C., wherein is a dynamic shear viscosity (Pa·s) measured in the process of decreasing the temperature, and ??1 is a dynamic shear viscosity (Pa·s) measured in the process of increasing the temperature, and ??2 being measured at the same temperature, and a value ??2 measured at 100° C. is 1000 Pa·s or less.

Abstract: Provided is a resin composition containing a hydrogenated crystalline dicyclopentadiene ring-opening polymer and a nucleator, wherein a content of the nucleator is 0.01 to 0.50 part by weight based on 100 parts by weight of the hydrogenated crystalline dicyclopentadiene ring-opening polymer, and a resin formed article comprising a hydrogenated crystalline dicyclopentadiene ring-opening polymer and a nucleator, wherein a content of the nucleator is 0.01 to 0.50 part by weight based on 100 parts by weight of the hydrogenated crystalline dicyclopentadiene ring-opening polymer. The resin composition containing a hydrogenated crystalline dicyclopentadiene ring-opening polymer is suitably used as a raw material for a low-polluting resin formed article, and a low-polluting resin formed article containing the hydrogenated crystalline dicyclopentadiene ring-opening polymer.

Abstract: The present disclosure provides a poly(spirobifluorene) having a structure represented by Formula (I). In the present disclosure, a polymer containing carbazolyl spirobifluorene is synthesized by introducing a carbazolyl group at a side chain of a spirobifluorene. No intramolecular charge transfer from a main chain to a side chain occurs in the carbazolyl spirobifluorene polymer prepared in the present disclosure. And the polymer has a good hole transport capability due to the modification with carbazole, and a good device efficiency can be achieved while retaining the advantage of the color purity of pure blue light. Meanwhile, by introducing an aromatic group to the poly(spirobifluorene) of the present disclosure, emission of three primary colors of blue, green and red can be obtained, and a good device efficiency can be achieved.

Abstract: The present invention concerns polyester resins of General Formula I (HO—[R1R2C(CH2—)]a[—OCOCxHyCO2—]b[—CpHzO—]c—H) or General Formula II (HO—[R1R2C(CH2—)2]a[—OCOCxHyCO2—]b[—CH2CR3(CO2H)CH2O]d—H), wherein R1, R2, a, b, c, d, x, y, p, and z are as defined herein, for use in inks and coating compositions. The polyester resins of the present invention are particularly, but not exclusively, suitable to enhance the adhesion between a printing ink or coating composition and a substrate, especially a plastic substrate, to which it is applied. The polyester adhesion promoters of the invention are compatible with urethane-based inks and coating compositions.

Abstract: A polymer is provided that preferably includes at least one unsaturated cycloaliphatic group. In one embodiment, the polymer is combined with an optional crosslinker and an optional carrier to form a coating composition suitable for use in coating articles such as packaging articles. In one embodiment, the polymer has at least one unsaturated cycloaliphatic group that is at least bicyclic.

Abstract: The present disclosure provides for improved binder compositions comprising an amine component, as well as methods for manufacturing articles and collections of matter comprising the disclosed binder compositions.

Abstract: The compound of the present application has a low melting point and excellent flexibility, and the like, so that a phthalonitrile resin or a prepolymer thereof or a polymerizable composition forming the same can exhibit excellent workability and a wide process window and it can be made to ensure improved impact strength. The compound can form the phthalonitrile resin or the like into a liquid phase or form it into a rubber phase. Such a phthalonitrile resin or the like can be applied to various applications.

Abstract: A thermoset polymer product comprising 4,4?-(((3-oxo-isoindoline-1,1-diyl)bis(4,1-arylene))bis(oxy))dibenzonitrile units of formula (2) wherein the units are derived from a 4,4?-(((3-oxo-isoindoline-1,1-diyl)bis(4,1-arylene))bis(oxy))diphthalonitrile monomer of formula (1) wherein R is a C1-25 hydrocarbyl, preferably a C1-6 alkyl, a phenyl, or a phenyl substituted with up to five C1-6 alkyl groups, more preferably a C1-3 alkyl or a phenyl; each occurrence of R2 and R3 is independently a hydrogen, a halogen, or a C1-25 hydrocarbyl, preferably a hydrogen, a halogen, or a C1-6 alkyl, more preferably a hydrogen or a C1-3 alkyl; p and q are each independently 0 to 4, preferably 0 or 1, more preferably 0; and G is a residue of a cyano group, and is a C1-25 hydrocarbyl linking group having a valence of at least 2.

Abstract: A 4,4?-(((3-oxo-isoindoline-1,1-diyl)bis(4,1-arylene))bis(oxy))diphthalonitrile compound of formula (1) wherein each occurrence of R1 is independently a hydrogen, a phenyl, or a C1-6 alkyl, more preferably a hydrogen or a C1-3 alkyl; each occurrence of R2 and R3 is independently a hydrogen, a halogen, or a C1-25 hydrocarbyl, preferably a hydrogen or a C1-6 alkyl, more preferably a hydrogen or a C1-3 alkyl; and r, p, and q are each independently 0 to 4, preferably 0 or 1, more preferably 0.

Abstract: A thermosetting composition, comprising a 4,4?-(((3-oxo-2-hydrocarbylisoindoline-1,1-diyl)bis(4,1-arylene))bis(oxy)) diphthalonitrile compound of formula (1) wherein R is a C1-12 hydrocarbyl, preferably a C1-6 alkyl or a C6-12 aryl; each occurrence of R2 and R3 is independently a hydrogen, a halogen, or a C1-25 hydrocarbyl, preferably hydrogen or a C1-6 alkyl, more preferably a hydrogen or C1-3 alkyl; and p and q are each independently 0 to 4, preferably 0 or 1, more preferably 0.

Abstract: An oligomer including two ends and a main chain located between the two ends, a group represented by Chemical Formula 1 at one end and a structural unit represented by Chemical Formula 2 or Chemical Formula 3 in the main chain: wherein, in Chemical Formulae 1 to 3, R1, Ar1, and Ar2 are the same as defined in the detailed description.

Abstract: A valve in the form of a medical device, article, or implant that is composed wholly or partly of a biomaterial, the biomaterial comprising a polyurethane or polyurethane urea elastomeric composition having a plurality of soft segments and hard segments, such that the plurality of soft segments are each derived from at least one block copolymer segment of Formula 1 and optionally an additional polyol or polyamine. The valve may include a plurality of valve leaflets and a support structure with one or more of the valve leaflets being composed wholly or partly of the biomaterial.

Abstract: Disclosed are a fluorine-silicon-containing polyphosphate ester and method for preparation thereof, having a chemical structural formula of: wherein R 1 is R 2 is n=10˜100. The fluorine-silicon-containing polyphosphate ester of the present invention uses silicon phosphorus and fluorine for improving flame retardancy. Phosphorus catalyzes the system to form a phosphorus-rich carbon layer, performing a protective-layer function and thereby preventing further breakdown of the epoxy resin. The silicon-containing epoxy resin forms a silica-containing carbon layer during the process of combustion, strengthening the carbon-layer structure and further improving the protective function of the carbon-layer. The introduction of elemental fluorine improves the thermal stability of the epoxy resin, thereby improving the flame retardancy performance of the system.

Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.

Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.

Abstract: The present invention relates to a composite having exceptional heat resistance and durability that exhibits quick response characteristics when used in an electrochromic device; an electrochromic device in which the composite is used; and a method for producing said composite and device. This composite contains an organic/metallic hybrid polymer that contains an organic ligand and a metal ion coordinated to the organic ligand, and an ionic liquid. The organic/metallic hybrid polymer forms ionic bonds with the ionic liquid. This electrochromic device comprises a first electrode, an electrochromic layer containing the composite, an electrolyte layer, and a second electrode.

Abstract: According to one inventive concept, a metallopolymer material includes a plurality of nanoparticles, a base, and water. Each of the nanoparticles includes a plurality of oligomer segments, where oligomer segments are coordinated to adjacent oligomer segments. Each of the oligomer segments includes a thiol and a metal.

Abstract: The present invention relates to the formation of gels. In particular, the present invention is directed to a method of forming a cross-linked polymer hydrogel using competitive ligand exchange.

Abstract: A method for producing a polyethylene nanocomposite by polymerizing ethylene in a polymerization mixture that contains a graphene-layered double hydroxide nanocomposite, a metallocene catalyst, an alkylaluminoxane co-catalyst, and an organic solvent to form a polyethylene nanocomposite in which the graphene-layered double hydroxide nanocomposite is dispersed in a matrix of polyethylene and wherein the graphene-layered double hydroxide nanocomposite contains 1 to 7 wt. % graphene relative to a total weight of the graphene-layered double hydroxide nanocomposite.

Abstract: Provided are resin particles including columnar resin particles each including filaments of a fibrous material, wherein the filaments of the fibrous material are aligned in an axial direction of each of the columnar resin particles.

Abstract: This invention relates to a process of making a fiber-reinforced composite. Glass fibers may be provided. These glass fibers may be treated with a sizing composition that has a coupling-activator compound with the formula: S-X-(A)n, where S represents a silicon-containing coupling moiety capable of bonding to the surface of glass fibers, X represents a linking moiety, and (A)n, represents one or more polymerization activator moieties. The treated glass fibers may be combined with a resin to make a fiber-resin mixture. The resin may have a monomer, a catalyst, and an activator compound capable of initiating a polymerization of the monomer. The monomer may be a lactam or lactone having 3-12 carbon atoms in the main ring. The fiber-resin mixture may then be cured so that the monomer polymerizes to form a thermoplastic polymer matrix of the fiber-reinforced composite. The thermoplastic polymer matrix may be formed by in situ polymerization initiated from both the surface of the glass fibers and the resin.

Abstract: A film includes a polymer composition, the polymer composition including a polymer, an organoclay, a primary amide slip agent, and a secondary amide slip agent different from the primary amide slip agent. The film can have static and kinetic coefficients of friction less than 0.25 as measured using ASTM D1894. The primary amide slip agent can be a primary erucamide slip agent. The film can be a multi-layered film.