Patents Issued in November 14, 2019
  • Publication number: 20190343682
    Abstract: The present invention includes a device for effecting deformation of a sclera of an eye, including an expandable, mesh tube having holes dispersed through an entire surface thereof and with first and second tapered ends, and inserted unexpanded to deform the sclera when expanded. A central portion is intrascleral, with the first and second tapered ends external to the sclera on top of an intact scleral surface to deform during expansion, and simultaneously causes the sclera to be deformed so that the sclera moves towards the inside of the eye while simultaneously causing the sclera to move towards the outside of the eye. The mesh tube includes struts, connecting points of the struts are of different sizes, the first and second tapered ends and the connecting points within the tapered ends are thicker than the connecting points of the mesh tube, and the mesh tube includes fixation tabs.
    Type: Application
    Filed: July 7, 2019
    Publication date: November 14, 2019
    Inventors: Ira H. Schachar, Ronald A. Schachar
  • Publication number: 20190343683
    Abstract: Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or ocular tissues is performed to address various types of vision correction.
    Type: Application
    Filed: May 14, 2019
    Publication date: November 14, 2019
    Inventors: Leonard Zheleznyak, Corey Leeson, Jonathan D. Ellis, Theodore Foos, Sam C. Butler
  • Publication number: 20190343684
    Abstract: Embodiments of this disclosure disclose an imaging system, including an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The beam source generates an electromagnetic radiation beam. The detection assembly generates a signal indicative of an intensity of a portion of the electromagnetic radiation beam reflected from the focal point location. A subsequent focal point of the electromagnetic radiation beam may be adjusted per the measured intensity signal. In some embodiments, an intensity signal below a lower threshold value may suggest a depth increase for a subsequent focal point. An intensity signal above an upper threshold value may suggest a depth decrease for a subsequent focal point. And, an intensity signal between the lower and upper thresholds may suggest a depth be maintained for a subsequent focal point. The focal point may be adjusted after each pulse or after a plurality of pulses.
    Type: Application
    Filed: July 25, 2019
    Publication date: November 14, 2019
    Inventors: Georg Schuele, Raymond Woo, John S. Hart
  • Publication number: 20190343685
    Abstract: A snow goggle device includes a composite lens and a spectacle frame fastened to a periphery of the composite lens. The composite lens includes a multi-layer sheet, a protective sheet spaced apart from the multi-layer sheet, and a combining layer connecting the multi-layer sheet and the protective sheet. The multi-layer sheet includes an anti-UV layer, an anti-fog layer, and a photochromic layer, the latter two of which are respectively disposed on an inner surface and an outer surface of the anti-UV layer. The photochromic layer has an adjustable transmittance that is changed when a UV light travels through the photochromic layer. The anti-UV layer can reflect a UV light to the photochromic layer. The multi-layer sheet, the protective sheet, and the combining layer jointly define an air layer that is configured to slow down the transference of an outer temperature of the protective sheet to the multi-layer sheet.
    Type: Application
    Filed: May 10, 2018
    Publication date: November 14, 2019
    Inventor: TZER-AN HUNG
  • Publication number: 20190343686
    Abstract: A heat transfer device particularly structured for application of thermal therapy from a contact surface to internal structures of a human ear. A device may be passive (pre-cooled), active (thermoelectrically active), or include elements of both. A device may be structured to apply thermal treatment from a contact surface of a contact cavity only to a localized posterior area relative to the circumference of an ear. A device may include both of a contact cavity and a bulk cavity, with heat transfer media disposed in each cavity. Typically, a bulk cavity holds at least twice the media volume contained in a contact cavity. The cavities may be disposed in fluid communication, or separated by a barrier to permit only thermal communication therebetween. When a barrier is present, a device may include different heat transfer media in each cavity. One or more device may be associated with a pair of auditory headphones to dispose a contact surface in contact with desired portion(s) of a head.
    Type: Application
    Filed: July 25, 2019
    Publication date: November 14, 2019
    Inventor: Curtis S. King
  • Publication number: 20190343687
    Abstract: Disclosed embodiments may relate to devices, systems, and methods for providing negative-pressure therapy simultaneously to a plurality of tissue sites using a single negative-pressure source. For example, a fluid bridge may comprise a plurality of distal ends, each configured to interact fluidly with a tissue site. In some embodiments, each distal end may have an aperture. The bridge may also comprise a port for entry of negative pressure into the enclosed space of the bridge. In some embodiments, each distal end may comprise a one-way valve. The enclosed space of the fluid pathway between the distal ends and the port may be supported in some embodiments, to prevent collapse due to negative pressure and/or compression.
    Type: Application
    Filed: July 29, 2019
    Publication date: November 14, 2019
    Inventors: Christopher Brian LOCKE, Thomas Alan EDWARDS
  • Publication number: 20190343688
    Abstract: The invention relates to an easy-to-use scar reduction bandage (or sticking plaster), that can be used in the case of hypertrophic scars and keloids. The invention offers a qualitatively even treatment over months by the permanent pressure achieved by the integrated scar bandage and spring. The effect can be strengthened or altered by the differing materials of upper and lower carrier sheets. Likewise, and at the same time, a supplemental treatment can be initiated by so-called storage structures in the base of the spring.
    Type: Application
    Filed: September 30, 2017
    Publication date: November 14, 2019
    Inventor: Adrian Giger
  • Publication number: 20190343689
    Abstract: A compression garment for a body includes a first material, an upper part having a first opening adapted to receive the body part, a central portion, and a lower part. The compression garment further includes a tensioning device adapted to adjust the level of compression of the garment on the body part.
    Type: Application
    Filed: December 11, 2017
    Publication date: November 14, 2019
    Applicant: JASA MEDICAL AS
    Inventors: Anette KLEPPA, Erling KLEPPA, Martin NESHEIM
  • Publication number: 20190343690
    Abstract: A body trunk supporter provided with: a belt-like lower band section that is adapted to be wrapped around and positioned at the pelvis of a user; an X-shaped stretchable middle band section that has a pair of lower end parts joined to the lower band section and that presses areas of the lumbar region of the user; and a pair of upper band sections that are jointed to a pair of upper end parts of the middle band section and that are adapted to be wrapped around and positioned at the chest of the user, wherein the pair of lower end parts of the middle band section are configured to be joined to areas ranging from positions that are immediately lateral to the pelvis of the user to adjacent anterior positions thereof in the lower band section; and the pair of upper band sections are configured to be separated from each other and to extend in bilaterally opposite directions in an unfolded state, and are configured to be wrapped around and positioned near fifth to tenth ribs of the chest of the user.
    Type: Application
    Filed: November 29, 2017
    Publication date: November 14, 2019
    Inventor: Yoshinobu ISHIDA
  • Publication number: 20190343691
    Abstract: An absorbent core comprising a front portion; a back portion; a middle portion positioned between the front portion and the back portion; and a longitudinal axis extending along a length of said core and crossing said front, middle and back portions, the absorbent core having a width extending perpendicular to said length and a perimeter comprising at least two opposing ends and at least two opposing sides positioned between said ends wherein the absorbent core comprises one or more channels having a first shape when the absorbent core is in dry state and a second shape when the absorbent core is in wet state and wherein said first and second shapes are different.
    Type: Application
    Filed: December 27, 2017
    Publication date: November 14, 2019
    Inventors: Ainas WEBER, Manfred BREU, Christel MAILINGER, Thomas HEEGE
  • Publication number: 20190343692
    Abstract: An absorbent organic material includes a non-permeable organic bottom layer. The bottom layer includes an upper and a lower surface. At least one core layer is disposed on the upper surface of the bottom layer. The at least one core layer includes a blend of degummed hemp fiber and a super absorbent polymer. An outermost layer includes a permeable composite of organic cotton and hemp fibers disposed on the at least one core layer.
    Type: Application
    Filed: May 10, 2019
    Publication date: November 14, 2019
    Inventor: Nia Peters
  • Publication number: 20190343693
    Abstract: An absorbent article or an array of absorbent articles of the present disclosure may have particular Product Length-to-Hip Silhouette(s).
    Type: Application
    Filed: July 26, 2019
    Publication date: November 14, 2019
    Inventors: Bret Darren SEITZ, Gary Dean LaVON, Jill TRYGIER, Vanessa MELENDEZ
  • Publication number: 20190343694
    Abstract: A disposable absorbent article may include a first waist region, a second waist region, a crotch region disposed between the first and the second waist regions, and a chassis having a topsheet, backsheet, absorbent core, and chassis periphery. The chassis periphery has a varying width, Wv.
    Type: Application
    Filed: July 23, 2019
    Publication date: November 14, 2019
    Inventors: Kumardipti CHATTERJEE, Jeromy Thomas RAYCHECK, Michael Devin LONG
  • Publication number: 20190343695
    Abstract: An underpants-type disposable diaper separately has a front side outer member and a back side outer member, the front side outer member and the back side outer member being spaced apart in a front-back direction in a middle in the front-back direction The back side outer member has a gluteal cover portion extending to a center side of the side seal portions in the front-back direction, and a front-back direction dimension of a side edge of the gluteal cover portion is 0.9 to 1.1 times a width direction dimension from a side edge of the back side outer member to a side edge of a center side of the side seal portions in the width direction.
    Type: Application
    Filed: October 16, 2017
    Publication date: November 14, 2019
    Applicant: Daio Paper Corporation
    Inventors: Aya Ide, Yosuke Mori
  • Publication number: 20190343696
    Abstract: A packaged absorbent article having a body surface and a garment surface; and a wrapper sheet for wrapping the absorbent article so that at least a portion of the garment surface of the absorbent article can be seen through the wrapper sheet.
    Type: Application
    Filed: July 25, 2019
    Publication date: November 14, 2019
    Inventors: YOSHIYUKI SHIMIZU, AKANE MATSUO, SACHIKO NINOMIYA, TSUNETOSHI MIURA
  • Publication number: 20190343697
    Abstract: The disposable limb cover for use in a shower is a garment. The disposable limb cover for use in a shower is worn by a patient during a shower. The disposable limb cover for use in a shower is worn over an appendage of the patient. The disposable limb cover for use in a shower is a fluid impermeable structure that protects the appendage of the patient while showering. The disposable limb cover for use in a shower comprises an extremity sheath, a joint wrap, a sleeve, and a fastener. The joint wrap attaches the extremity sheath to the sleeve. The joint wrap and the fastener bind the disposable limb cover for use in a shower to the patient.
    Type: Application
    Filed: May 8, 2018
    Publication date: November 14, 2019
    Inventors: BRITTANY FARLEY, Ed Lewis
  • Publication number: 20190343698
    Abstract: A suspension for a vehicle is provided. The suspension includes, for example, a frame, at least one drive assembly and at least one caster pivot arm. The at least one drive assembly and the at least one caster pivot arm are pivotally connected to the frame at a common pivot axis such that the drive assembly and the front caster pivot arm are pivotable relative to one another.
    Type: Application
    Filed: April 22, 2019
    Publication date: November 14, 2019
    Inventors: Robert Bekoscke, Damon Jurkiewicz
  • Publication number: 20190343699
    Abstract: A medical chair includes a base, a seat, and a leg rest pivotally mounted relative to the seat and adapted to move between an extended position and a retracted position. The chair further includes a first actuator for tilting the seat with respect to the base, a second actuator for lifting the seat with respect to the base, and a leg rest actuator adapted to move the leg rest. The chair also includes a controller adapted to control the first and second actuators to move the seat between a first position and a second position such that the seat is both lifted and tilted at the same time as the seat moves from the first position to the second position, and wherein the controller is adapted to control the leg rest actuator such that the leg rest maintains a substantially constant orientation with respect to the floor.
    Type: Application
    Filed: May 23, 2019
    Publication date: November 14, 2019
    Inventors: Joseph Adam Upchurch, Christopher S. Hough, Richard A. Derenne, Cory Patrick Herbst
  • Publication number: 20190343700
    Abstract: The invention relates to the field of medical technology, and more particularly to multi-functional hospital beds. The claimed structure comprises a vertical stand in the shape of an inverted L, which is connected to a folding bed. The bed has two sections, one of which can be folded onto the other, whereupon both sections can be folded to the vertical stand. A movable frame is disposed in the top corner of the stand, wherein said frame can be fastened in two positions: to the top part of the stand, and also at an angle of 45 degrees to the stand. A motor is provided, which pulls a cable. Said cable passes through the stand and the end of the movable frame. This provides two operating modes: Mode 1 is that of a bed. In this case, the frame is fastened to the stand, and the bed is unfolded. Traction or fixation can be applied to individual parts of a patient's body. Mode 2 is that of a standing aid. In this case, the bed is folded, and the frame is positioned at an angle of 45 degrees.
    Type: Application
    Filed: December 23, 2016
    Publication date: November 14, 2019
    Inventor: Alexandr Urievich Ivanov
  • Publication number: 20190343701
    Abstract: A transport device is for carrying and moving objects from one location to another. In an embodiment, the transport device includes a chassis and at least four motor-driven omnidirectional wheels arranged on the chassis. The chassis is configured to adapt the wheelbase and the track gauge of the omnidirectional wheels according to the size of the object. A corresponding method for operating such transport device is further specified in an embodiment. The embodiments of the application lie in the universal usage of the transport device for nearly all sizes and shapes of an object.
    Type: Application
    Filed: September 1, 2017
    Publication date: November 14, 2019
    Inventors: Franz DIRAUF, Thorsten GECKS
  • Publication number: 20190343702
    Abstract: The present invention includes an apparatus for transdermal treatments comprising: an openable enclosure for a subject in communication with three or more sources of treatment modalities selected from: a source of ozone; a source of steam, a source of CO2/Carbonic Acid; a source of Far Infrared; and a source of pulsed electromagnetic fields (PEMF), wherein each of the three or more sources is in communication with an interior of the openable enclosure to treat the subject transdermally.
    Type: Application
    Filed: May 9, 2018
    Publication date: November 14, 2019
    Inventor: André Hugo Smith
  • Publication number: 20190343703
    Abstract: A cleaning device system to clean a surgical scope, which cleaning device system includes an attachment element to attach the cleaning device, being positioned outside the body of a patient, to a trocar. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. § 1.72(b). As stated in 37 C.F.R. § 1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.
    Type: Application
    Filed: April 23, 2019
    Publication date: November 14, 2019
    Inventor: Claude FISET
  • Publication number: 20190343704
    Abstract: A surgical boot system and sleeve accessory for hip distraction. The surgical boot system includes an L-shaped rigid shell having a proximal portion and a distal portion. A soft liner is attached to the rigid shell and extends along at least one of the proximal portion and the distal portion. The surgical boot system also includes at least one strap assembly (which can be a plurality of strap assemblies) extending around the rigid shell. A load transmission hoop is connected to and extends around the distal portion of the rigid shell and an attachment point is connected to the load transmission hoop. The rigid shell is pivotable about the attachment point. Specifically, the attachment point is configured to interface with a hip distractor apparatus in a way that allows for multiple degrees of freedom.
    Type: Application
    Filed: May 9, 2019
    Publication date: November 14, 2019
    Applicant: Conmed Corporation
    Inventor: Benjamin Willard
  • Publication number: 20190343705
    Abstract: In one aspect, an orthosis for increasing range of motion of a body joint generally includes first and second dynamic force mechanisms for simultaneously applying a dynamic force to body portions on opposite sides of a body joint.
    Type: Application
    Filed: May 28, 2019
    Publication date: November 14, 2019
    Applicant: Bonutti Research, Inc.
    Inventors: Peter M. Bonutti, Glen A. Phillips, Joseph Mathewson
  • Publication number: 20190343706
    Abstract: A muscle activation system including: an inclined platform for a user to stand on; a rigid upper body user support frame attached to the inclined platform for supporting the upper body of a user standing on the inclined platform; a base, coupled to the inclined platform, the coupling allowing relative orientation motion between the base and inclined platform. The platform adapted to undergo a precession like motion around a central point so as to circumferentially move a user's upper body, when supported by the rigid upper body user support frame, substantially through an arc around a central point.
    Type: Application
    Filed: March 7, 2017
    Publication date: November 14, 2019
    Inventor: Geoffrey Redmond
  • Publication number: 20190343707
    Abstract: A soft wearable muscle assisting device has at least a wearable body interface and attached thereon elements of active and passive components, adapted to together assist a user in changing or maintaining a position of a first body part articulated to a second body part. The wearable body interface comprises at least two gar-ment portions. The active and passive components comprise at least one actively powered element. The passive components comprise at least a first passive component and a second passive component that both extend between the at least two garment components and comprise elastic material for storing energy provided by the user and/or by the at least one actively powered element. The first and a second passive components are arranged on opposite sides of a joint of the body.
    Type: Application
    Filed: December 21, 2017
    Publication date: November 14, 2019
    Applicant: ETH Zurich
    Inventors: Robert Riener, Jaime Duarte, Kai Schmidt
  • Publication number: 20190343708
    Abstract: A passive range of motion device is disclosed. The passive range of motion device is configured to deliver passive rotational motion to a joint, such as a hip joint. Although the use of passive range of motion devices to deliver postoperative physical therapy to hip or shoulder joints is widespread, these devices deliver motion therapy in only one plane. The hip and shoulder joints, however, allowing motion of the leg or arm in multiple planes. A device for delivering passive range of motion therapy in multiple planes to a joint, such as a hip joint or a shoulder joint, is described. The device may have a processing unit for storing user information and device status information. The device may be controlled by a controller attached to the device, or remotely, such as by a remote desktop computer or a mobile computing device.
    Type: Application
    Filed: May 13, 2019
    Publication date: November 14, 2019
    Inventor: Pavel Ivanov
  • Publication number: 20190343709
    Abstract: The Wardlow Seat Strap is a seat that attaches to any standard hospital walker and gives the user a place to sit down as needed to reduce the risk of falling while using the walker.
    Type: Application
    Filed: May 31, 2018
    Publication date: November 14, 2019
    Inventor: Baari Wardlow
  • Publication number: 20190343710
    Abstract: An exoskeleton device is provided herein that includes a control unit having at least one actuator. A transmission assembly operably couples the control unit to a hinged assembly. A sensor is coupled to the hinged assembly and is configured to acquire data in reference to use of the hinged assembly. The exoskeleton device also includes a feedback modality. A controller is in communication with the sensor and feedback modality. The controller is configured to activate the feedback modality based on a measured performance metric that is determined from the acquired data.
    Type: Application
    Filed: May 10, 2019
    Publication date: November 14, 2019
    Inventor: Zachary F. LERNER
  • Publication number: 20190343711
    Abstract: An compression therapy device which improves on available products by combining the efficacy of bulky, active pneumatic devices with a convenience approaching that of a passive non-pneumatic device. This is achieved by using an air cell (6) with a flexible inner and a rigid outer wall (10) which enables therapeutic pressures to be achieved at lower overall inflation volume. This in turn allows miniature low power, silent pump (3) to be used enabling the device to be worn unobtrusively under clothing. Such a device is targeted at users with long term chronic venous conditions, variants of oedema, recovering from surgery, requiring travel comfort, improved leg circulation or accelerated recovery from exercise or injury.
    Type: Application
    Filed: February 20, 2017
    Publication date: November 14, 2019
    Inventor: Peter lee CROSSLEY
  • Publication number: 20190343712
    Abstract: The present disclosure provides an inductive therapeutical instrument generating electric current and a skin care method, and relates to the field of skin care apparatuses. The above inductive therapeutical instrument is mainly used for applying a material body to the skin and massaging and maintaining the skin. The inductive therapeutical instrument mainly includes a material storage container and a massage head. The material body is stored in the material storage container, and the material body is squeezed into the massage head by squeezing the material storage container, and is applied to the skin through a material discharging hole on the massage head. Moreover, during use, the inductive therapeutical instrument can generate a microcurrent that acts on the skin so as to improve the skin condition.
    Type: Application
    Filed: May 9, 2019
    Publication date: November 14, 2019
    Applicant: Guangzhou Mozhen Electronic Technology Co., LTD.
    Inventors: Lizhi CHENG, Guifang HUANG
  • Publication number: 20190343713
    Abstract: A compartmentalized massage roller is disclosed facilitating a unitary structure for separable components, and thus capable of providing a plurality of massage techniques. The massage roller can contain an outer sleeve and an inner roller, wherein the outer sleeve defines a hollow opening configured to receive and enclose the inner roller. The inner roller is removably secured to the outer sleeve through frictional forces exerted through contact between the inner roller and hollow opening surface. The outer sleeve can define a plurality of curvy ridges configured to target softer muscles. The inner roller can contain a plurality of inner ridges configured to mimic myofascial release therapy typically conducted by fingers. The inner ridges further define a plurality of troughs, each located between a pair of adjacent inner ridges, wherein the troughs are configured to encapsulate and secure muscles to release binding collagen.
    Type: Application
    Filed: May 10, 2018
    Publication date: November 14, 2019
    Applicant: MPD Holdings, Inc.
    Inventor: Glenn M. Boghosian
  • Publication number: 20190343714
    Abstract: Methods and devices are described for performing at least one of enhancing female sexual arousal, enhancing female sexual pleasure, or enhancing an ability to achieve or experience a more pleasurable orgasm for a female. In some cases, an acoustic wave stimulus is combined with one or more of providing a suction stimulus and a vibration stimulus as this may be further beneficial to the female.
    Type: Application
    Filed: September 21, 2018
    Publication date: November 14, 2019
    Inventor: Robert Gordon
  • Publication number: 20190343715
    Abstract: A personal therapy device, directed generally to an elongated sexual stimulation device for female use having advanced shape motion control and shape transformation. In one embodiment, the device has a flexible outer body elongated in a longitudinal direction and a shape memory alloy (SMA) thrust actuator disposed within the flexible outer body. In another embodiment, the device includes one or more skeletal segments which are disposed within the flexible outer body and capable of deformation in various directions. In yet another embodiment, the device includes one or more rotational servo motor pair units, where each rotational servo motor of the rotational servo motor pair has an eccentric weight, and the synchronized rotation of the eccentric weight pair generates a net lateral wobbling motion. In yet another embodiment, the device includes an external positioning sensor unit, an inertial measurement unit, one or more pressure sensors, or a combination thereof.
    Type: Application
    Filed: May 9, 2019
    Publication date: November 14, 2019
    Inventor: Michael Kemp
  • Publication number: 20190343716
    Abstract: A massage assembly for providing a massage while a user sits on a toilet includes a toilet that has a tank, a seat and a lid. A massage unit is attached to the toilet and the massage unit massages a user when the user sits on the lid.
    Type: Application
    Filed: May 9, 2018
    Publication date: November 14, 2019
    Inventor: Joycelyn M. Johnson-Kendrick
  • Publication number: 20190343717
    Abstract: A three-dimensional acupoint mapping method executable by a computing device is disclosed. The present invention comprises the steps of: (a) making use of a three-dimensional standard image inclusive of a three-dimensional image for an internal tissue of the human body to produce a standard template of the internal tissue for determining a standard location of an acupoint; and (b) determining the standard location of the acupoint where a location of the internal tissue is considered on the three-dimensional standard image on the basis of the standard template of the internal tissue to map the determined standard location onto the three-dimensional standard image; wherein the standard locations indicate three-dimensional coordinates in the body for the acupoints.
    Type: Application
    Filed: February 23, 2018
    Publication date: November 14, 2019
    Inventor: Yun Kyoung YIM
  • Publication number: 20190343718
    Abstract: The pillow of the present disclosure comprises: a first unit body and a second unit body which are arranged side by side in the left and right directions and are connected to each other with a variable gap therebetween; a third unit body which is coupled to the first unit body so as to move relative thereto in the forward and backward directions; a fourth unit body which is coupled to the second unit body so as to move relative thereto in the forward and backward directions, disposed in parallel to the third unit body in the left and right directions and coupled thereto with a variable gap therebetween; a first gap adjusting unit for allowing the third unit body and the fourth unit body to get further apart from or closer to each other in the forward and backward directions with respect to the first unit body and the second unit body; and a second gap adjusting unit for allowing the first unit body and the third unit body to get further apart from or closer to each other in the left and right directions with
    Type: Application
    Filed: January 4, 2018
    Publication date: November 14, 2019
    Inventors: Hye Jeong SHIN, Ji Woong PARK
  • Publication number: 20190343719
    Abstract: The present invention relates to methods for treating diseases or conditions in which proprotein convertase subtilisin/kexin type 9 (PCSK9) expression or activity causes an impact by administration of PCSK9-specific antibodies or antigen-binding fragments thereof and preferably by additional administration of an inhibitor of 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase). The present invention further relates to PCSK9-specific antibodies or antigen-binding fragments thereof for use in the treatment of diseases or conditions in which PCSK9 expression or activity causes an impact. The present invention also relates to articles of manufacture comprising packaging material, PCSK9-specific antibodies or antigen-binding fragments thereof, and a label or packaging insert indicating which groups of patients can be treated with said antibodies or fragments, which groups of patients must not be treated with said antibodies or fragments, and which dosage regimen should be used.
    Type: Application
    Filed: March 26, 2019
    Publication date: November 14, 2019
    Inventors: Corinne Hanotin, Laurence Bessac, Umesh Chaudhari
  • Publication number: 20190343720
    Abstract: A hollow body includes a wall which at least partially surrounds an interior volume of the hollow body. The wall comprises a layer of glass comprising a first glass composition, comprises a base surface, and has a wall surface. The wall surface comprises at least one surface region, in which the base surface is at least partially superimposed by at least one elevated region, and at least one contact region, which extends along a contact range of a height of the hollow body. The at least one elevated region comprises a further glass composition. An exterior diameter of the hollow body has a maximum throughout the contact range. The at least one surface region is at least partially positioned in the at least one contact region.
    Type: Application
    Filed: May 10, 2019
    Publication date: November 14, 2019
    Applicant: Schott AG
    Inventors: Stephanie Mangold, Eveline Rudigier-Voigt, Tamara Sweeck
  • Publication number: 20190343721
    Abstract: A supporting structure for concurrently supporting a plurality of containers for substances for pharmaceutical, medical or cosmetic applications, comprises a plurality of receptacles. The receptacles are arranged in a regular arrangement, are formed by circumferential side-walls, and an upper side of the supporting structure is formed as a plate-shaped carrier. The receptacles are polygonal in shape when viewed in a plan view. A side-wall is formed as a common partition wall between respective two directly adjacent receptacles of the plurality of receptacles. The receptacles can be directly adjacent to each other, which enables optimum packing density, especially with a hexagonal basic shape of the receptacles. Due to the shared partition wall, filigree, double-walled structures can be effectively avoided, which considerably simplifies production by injection molding from a plastic material. Thereby, also a very high inherent stiffness of the supporting structure can be achieved.
    Type: Application
    Filed: May 14, 2019
    Publication date: November 14, 2019
    Applicant: SCHOTT Schweiz AG
    Inventors: Christian Komann, David Hilber, Markus Renz
  • Publication number: 20190343722
    Abstract: A syringe for receiving a fluid from a container. The syringe comprises a barrel for housing the fluid and including an end wall with an opening defined therein, a plunger for slidable engagement within the barrel, and moveable between a retracted position and an extended position, and a needle. The needle has a first end anchored to the plunger and a second distal end, a conduit defined by the needle, and an inlet offset from the second distal end for fluid communication with an opening defined at the second distal end. The plunger includes a plunger seal for engagement within the barrel, the plunger seal defining a passage for receiving the needle. The syringe further comprises an engagement system having a complementary feature to cooperatively engage with a complementary feature of the container to mount the container to the syringe.
    Type: Application
    Filed: December 6, 2017
    Publication date: November 14, 2019
    Applicant: INJEC TECHNOLOGIES INC/LES TECHNOLOGIES INJEC INC.
    Inventor: Catherine Reisenburg MOLSON
  • Publication number: 20190343723
    Abstract: A cap assembly includes an access member including a first section and a second section. The first section includes a connection portion that is attachable to an extraction device that extracts contents of a reservoir. The connection portion includes a first opening. The second section includes a second opening in fluid communication with the contents of the reservoir when the access member is secured to the reservoir. The cap assembly includes a valve member insertable into the access member so as to be in fluid communication with the first opening and the second opening and such that the valve member i) seals the contents of the reservoir at the first opening when the connection portion is not attached the extraction device, and ii) provides access to the contents of the reservoir through the first opening when the connection portion is attached to the extraction device.
    Type: Application
    Filed: July 25, 2019
    Publication date: November 14, 2019
    Inventor: Robbie KLIMEK
  • Publication number: 20190343724
    Abstract: The assembly comprises: a stand for hanging a container of a main liquid, a spike, to be introduced into the container of main liquid, a multi-inlet connector with inlet tubings, to be connected to containers of additional liquids and to the container of main liquid through the spike, and an outlet tubing to be connected to a luer syringe to be introduced into a patient. The length of the spike inlet tubing of the connector has a length determined for, during use of the assembly with a container of main liquid, keeping the connector hung up on the stand through the spike and the container of main liquid. Thanks to the invention, the problem of the tubing traffic is solved.
    Type: Application
    Filed: April 15, 2019
    Publication date: November 14, 2019
    Applicant: Benta Pharma Industries Europe Sarl
    Inventors: Bernard TANNOURY, Daniel Boulos
  • Publication number: 20190343725
    Abstract: Liquid drug transfer devices including an integral telescopic vial adapter for telescoping from an initial pre-compacted state to a final compacted state. In the initial pre-compacted state, the vial adapter telescopically snap fits on an initially non-punctured intact discrete injection vial leaving its injection vial stopper non-punctured. In the final compacted state, the vial adapter punctures the injection vial stopper. The liquid drug transfer device is used with an intact discrete injection vial release tool for applying a pincers-like compression for convenient release of a non-punctured intact discrete injection vial in the initial pre-compacted state. The vial adapter includes a clamping arrangement for irreversibly clamping same in the final compacted state. The vial adapter precludes release of a punctured discrete injection vial in its final compacted state.
    Type: Application
    Filed: November 29, 2017
    Publication date: November 14, 2019
    Inventor: Igor DENENBURG
  • Publication number: 20190343726
    Abstract: A cartridge for dispensing a pre-measured buffering agent together with a medical fluid such as dental anesthetic. The cartridge includes a sharp piercing element at one end, a frangible barrier proximate the piercing element, and a traveling closure. The buffering solution is in a chamber between the barrier and the closure. When loaded into a syringe and subjected to operating pressures, the barrier is pierced, enabling the buffering solution to mix with the medical fluid. Continued pressure propels a desired, controlled mixture into a tissue of a patient. A dye may be included for visual confirmation of mixing.
    Type: Application
    Filed: July 25, 2019
    Publication date: November 14, 2019
    Inventor: William J. Moore DMD
  • Publication number: 20190343727
    Abstract: Mobile systems and methods are adapted to control and document prehospital patient care reports and communication of patient status to a receiving medical treatment facility. The systems and methods relate to systems and methods for managing, recording, and administering drugs such as narcotics in an ambulatory and/or emergency environment.
    Type: Application
    Filed: March 8, 2019
    Publication date: November 14, 2019
    Inventors: Karl Schulz, Richard Campbell, Emily Huang, Sarah Koh, Kurnhee Ma
  • Publication number: 20190343728
    Abstract: Adjustable indicators for containers and methods for using and making the same are provided. In one embodiment, a cap includes a closure body defining a closure space, a dial, an external force interface, a path portion defining a path, and an interaction feature including an extender that is operative to move along the path, wherein application of external force on the external force interface is operative to move the extender in a first direction along a first segment of the path, at least partial termination of the external force on the external force interface is operative to move the extender in a second direction along a second segment of the path, and movement of the extender along the second segment of the path in the second direction is operative to rotate the dial body about an axis within the closure space.
    Type: Application
    Filed: December 21, 2018
    Publication date: November 14, 2019
    Inventor: Arthur Nazginov
  • Publication number: 20190343729
    Abstract: A concealable feeding tube assembly includes a tube and a removable member. The tube has an insertion portion and a feeding portion respectively at two ends thereof. The feeding portion is configured for insertion into a nasal cavity of a patient and intercommunicates with the insertion portion. The removable member is detachably attached to the tube and is configured to seal the feeding portion. The removable member includes an abutment portion extending beyond a lateral face of the removable member.
    Type: Application
    Filed: May 10, 2019
    Publication date: November 14, 2019
    Inventor: Jui-Che Hsu
  • Publication number: 20190343730
    Abstract: The present invention relates to an aqueous dental glass ionomer composition for use in the treatment of cavitated carious lesions, which composition comprises a water-soluble, polymerizable polymer comprising acidic groups, which is reactive with the particulate glass in a cement reaction, whereby the polymerizable polymer has a polymer backbone and pendant groups having one or more polymerizable carbon-carbon double bonds. The dental glass ionomer composition is used as a permanent direct restoration.
    Type: Application
    Filed: December 13, 2017
    Publication date: November 14, 2019
    Applicant: DENTSPLY SIRONA Inc.
    Inventors: SZILLAT Florian, Caroline RENN, Christoph WEBER, Uwe WALZ, Joachim Klee
  • Publication number: 20190343731
    Abstract: The coating formation method of the present invention is a method for forming a coating on a surface of a coating formation target. The formation method of the present invention includes an electrostatic spraying step of electrostatically spraying a composition directly onto the coating formation target, thereby forming a coating composed of a deposit containing fibers. The composition contains a component (a), a component (b), and a component (c) below. (a) One or more volatile substances selected from water, alcohols, and ketones. (b) A polymer having coating formability. (c) A liquid agent containing one or more selected from oils and polyols that are in a liquid form at 20° C.
    Type: Application
    Filed: December 27, 2017
    Publication date: November 14, 2019
    Applicant: Kao Corporation
    Inventors: Naomi AMARI, Takehiko TOJO, Kenta MUKAI