Patents Issued in November 21, 2019
  • Publication number: 20190351218
    Abstract: The disclosure is directed to securing electrodes of a medical lead adjacent to a target tissue site. The medical lead may include one or more threaded fixation structures disposed circumferentially about the outer surface of the lead body, or elongated member, that resembles a “screw” or “auger.” During implantation, a clinician may rotate the entire lead to “screw” the lead into the tissue of the patient until electrodes of the lead reside adjacent to a target tissue. In this manner, the threaded fixation structure secures the lead within the patient to resist lead migration and improper therapy and provide a fine adjustment for depth of placement. The threaded fixation structure may be disposed on a portion of the lead proximal to or distal to the electrodes of the lead or over the portion of the lead that includes the electrodes.
    Type: Application
    Filed: July 31, 2019
    Publication date: November 21, 2019
    Inventor: Martin T. Gerber
  • Publication number: 20190351219
    Abstract: Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged along an elongated probe shaft. The microelectrode elements are dimensioned and shaped so as to target individual neurons, groups of neurons, and neural tissue as may be located in an animal nervous system, such as deep within a human brain. Beneficially, the neurological probe can be used to facilitate location of the neurological target and remain implanted for long-term monitoring and/or stimulation.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 21, 2019
    Inventors: Andre MERCANZINI, Philippe RENAUD
  • Publication number: 20190351220
    Abstract: Presented herein are techniques that enable electroporation of the cells of a recipient of a tissue-stimulating prostheses while the tissue-stimulating prosthesis is implanted in the recipient. Tissue-stimulating prostheses in accordance with embodiments presented herein are configured such that the stimulation electronics (e.g., current sources and integrated circuit) of the prosthesis are not exposed to the high voltages used in electroporation.
    Type: Application
    Filed: May 9, 2019
    Publication date: November 21, 2019
    Inventors: Torsten Lehmann, Paul Michael Carter, John Michael Heasman
  • Publication number: 20190351221
    Abstract: The present invention relates to a lead paddle positioning and/or deployment system comprising at least a stylet and a lead paddle, wherein the lead paddle comprises at least one guiding channel and wherein the stylet comprises at least one guiding wire at its distal end, which is configured and arranged to be engaged and/or to be at least partially received in the guiding channel. The present invention relates further to a stylet for a lead paddle system comprising the stylet features. Furthermore, the present invention relates to a lead paddle for a lead paddle system comprising the lead paddle features.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 21, 2019
    Inventors: Damian GANTY, Vincent DELATTRE
  • Publication number: 20190351222
    Abstract: Disclosed herein is an implantable medical device for implantation against cardiac tissue in the administration of electrotherapy to the cardiac tissue. The device includes a distal end and a monolithic controlled release device. The distal end includes a housing structure and a cavity within the housing structure. The cavity opens exterior the implantable medical device via a distal opening. The monolithic controlled release device is within the cavity and proximal the distal opening. The monolithic controlled release device includes a distal face, a proximal face opposite the distal face, an outer circumferential surface extending between the distal face and the proximal face, and a spline-shaped inner lumen extending between the distal face and the proximal face and radially inward from the outer circumferential surface. The monolithic controlled release device further includes an active pharmaceutical ingredient.
    Type: Application
    Filed: May 21, 2018
    Publication date: November 21, 2019
    Inventors: Tyler J. STRANG, Benjamin F. JAMES, IV, Matthew MALONE
  • Publication number: 20190351223
    Abstract: A bone implant kit includes an implant and first and second electrical stimulation anchors. The implant defines an inner surface inner configured to face a bone to which the bone implant kit is configured to attach, and an outer surface opposite the inner surface. The implant further defines first and second bone fixation holes that each extend from the inner surface to the outer surface. The first and second bone fixation holes are spaced from each other along a longitudinal direction. The first electrical stimulation anchor can be sized and configured for insertion into the first bone fixation hole, and the second electrical stimulation anchor can be sized and configured for insertion into the second bone fixation hole. The first and second electrical stimulation anchors can be configured to respond to a magnetic field so as to generate an electric field between the first and second electrical stimulated anchors.
    Type: Application
    Filed: May 16, 2018
    Publication date: November 21, 2019
    Inventors: Jochen Walser, Mario Gehri, Andre Furrer
  • Publication number: 20190351224
    Abstract: A system and method for selectively treating aberrant cells such as cancer cells through administration of a train of electrical pulses is described. The pulse length and delay between successive pulses is optimized to produce effects on intracellular membrane potentials. Therapies based on the system and method produce two treatment zones: an ablation zone surrounding the electrodes within which aberrant cells are non-selectively killed and a selective treatment zone surrounding the ablation zone within which target cells are selectively killed through effects on intracellular membrane potentials. As a result, infiltrating tumor cells within a tumor margin can be effectively treated while sparing healthy tissue. The system and method are useful for treating various cancers in which solid tumors form and have a chance of recurrence from microscopic disease surrounding the tumor.
    Type: Application
    Filed: July 24, 2019
    Publication date: November 21, 2019
    Inventors: Michael B. Sano, Christopher B. Arena, Scott S. Verbridge, Rafeal V. Davalos
  • Publication number: 20190351225
    Abstract: An apparatus is provided for injecting a fluid into body tissue, the apparatus comprising: a hollow needle; and fluid delivery means, wherein the apparatus is adapted to actuate the fluid delivery means in use so as to automatically inject fluid into body tissue during insertion of the needle into the said body tissue.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 21, 2019
    Inventors: Iacob Mathiesen, Torunn E. Tjelle, Knut Arvid Sorensen Rekdahl, Bjorn David-Andersen
  • Publication number: 20190351226
    Abstract: The present invention relies on a controller-transmitter device to deliver ultrasound energy into cardiac tissue in order to directly improve cardiac function and/or to energize one or more implanted receiver-stimulator devices that transduce the ultrasound energy to electrical energy to perform excitatory and/or non-excitatory treatments for heart failure. The acoustic energy can be applied as a single burst or as multiple bursts.
    Type: Application
    Filed: January 16, 2019
    Publication date: November 21, 2019
    Inventors: Debra S. Echt, Richard E. Riley, Mark W. Cowan, Axel F. Brisken
  • Publication number: 20190351227
    Abstract: The invention relates to medicine, and more particularly to physiotherapy, neurology, traumatology, orthopaedics, rehabilitation and sports medicine, and can be used for relaxing spasmed muscles when treating patients with different conditions of the musculoskeletal and nervous systems, and also for prophylaxis in the social sphere. For this purpose, relaxed antagonist muscles are subjected to a stimulating electric impulse effect at an impulse frequency of from 15 to 35 Hz, with an impulse signal duration of from 5 to 60 ?s and a working signal level of from 5 to 75% of the strength of a signal at which the patient feels a vibration. Spasmed agonist muscles are subjected to a relaxing thermal effect at a temperature of from 42 to 60° C. In addition, the segments of the spinal cord responsible for innervating the agonist-antagonist muscle pairs undergoing treatment are subjected to a thermal effect at a temperature of from 42 to 60° C.
    Type: Application
    Filed: January 23, 2018
    Publication date: November 21, 2019
    Inventors: Gennady Petrovich FESKOV, Anna Yurievna LITUS
  • Publication number: 20190351228
    Abstract: A medical device containing a sensor, a motor, one or more plates, and a control unit, for treating diabetes. The medical device vibrates the pancreas thereby improving blood and secretory hormone circulation and enhancing the production of insulin.
    Type: Application
    Filed: May 17, 2018
    Publication date: November 21, 2019
    Applicant: Imam Abdulrahman Bin Faisal University
    Inventor: Ahmed Abdelkarim MANSI
  • Publication number: 20190351229
    Abstract: A lead system and method of use for treating breathing disorders by the transvenous stimulation of the phrenic nerve.
    Type: Application
    Filed: July 29, 2019
    Publication date: November 21, 2019
    Inventors: Randy W. Westlund, Mark Gelfand
  • Publication number: 20190351230
    Abstract: An electrostimulation device includes a computer generating an electrostimulation generator control signal and outputting a music signal, a transcutaneous electrostimulation generator, an electronic signal conduit, and an electrode coupler. The generator wirelessly receives the generator control signal and the music signal, generates a nerve electrostimulation signal dependent upon the generator control signal, and wirelessly outputs the nerve electrostimulation signal at the stimulation output and the music signal at an audio output. The coupler fits in an ear canal, has a speaker connected to the audio output to output the music signal into the ear canal when worn, and has electrostimulation electrodes wirelessly connected to the stimulation output through the electronic signal conduit to receive the nerve electrostimulation signal and positioned to contact tissue within the canal to transcutaneously apply the nerve electrostimulation signal thereto.
    Type: Application
    Filed: November 19, 2018
    Publication date: November 21, 2019
    Inventors: Richard Cartledge, Daniel Cartledge, Ami Brannon, Kermit Falk, Gregory L. Mayback
  • Publication number: 20190351231
    Abstract: The present invention relates to the medical field, in particular to the treatment of neurological disorders. More specifically the present invention relates to a nanoparticle or nanoparticles' aggregate for use in prevention or treatment of a neurological disease or at least one symptom thereof in a subject when the nanoparticle or nanoparticles' aggregate is exposed to an electric field, wherein the nanoparticle's or nanoparticles' aggregate's material is selected from a conductor material, a semiconductor material, an insulator material with a dielectric constant ?ijk equal to or above 200, and an insulator material with a dielectric constant ?ijk equal to or below 100. It further relates to compositions and kits comprising such nanoparticles and/or nanoparticles' aggregates as well as to uses thereof.
    Type: Application
    Filed: December 19, 2017
    Publication date: November 21, 2019
    Inventors: MARIE-EDITH MEYRE, AGNÈS POTTIER, LAURENT LEVY
  • Publication number: 20190351232
    Abstract: Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
    Type: Application
    Filed: August 1, 2019
    Publication date: November 21, 2019
    Inventors: Maria E. Bennett, Joseph W. Boggs, Warren M. Grill, John Chae
  • Publication number: 20190351233
    Abstract: Some systems and methods may facilitate selection of a vector for delivering electrical stimulation to a patient's heart. One method may include displaying a plurality of vectors on a display screen wherein each vector represents a different combination of three or more electro-stimulation electrodes, determining an electrical impedance for each of the plurality of vectors, displaying on the display screen the electrical impedance for each of the plurality of vectors, receiving a selection of a set of the plurality of vectors, determining, for each of the vectors in the set of vectors, a capture threshold, displaying on the display screen the capture threshold for each of the vectors in the set of vectors, receiving a selection of a vector from the set of vectors for delivery of electrical stimulation to the patient's heart, and programming the electro-stimulation device electrical stimulation to the patient's heart via the selected vector.
    Type: Application
    Filed: July 30, 2019
    Publication date: November 21, 2019
    Inventors: Holly E. Rockweiler, Sunipa Saha, Keith L. Herrmann, Yinghong Yu, Joel A. Krueger
  • Publication number: 20190351234
    Abstract: An example of a system includes a blood pressure modulation device and a controller. The blood pressure modulation device may be configured to deliver a therapy to chronically maintain blood pressure within a prescribed range. The blood pressure modulation device may include a neuromodulator configured to deliver neuromodulation energy to neural tissue in a spinal cord or near the spinal cord using a first parameter set. The controller may include analyzer circuitry configured to determine an actual or anticipated blood pressure demand event indicated for a blood pressure change, and therapy parameter adjuster circuitry configured to respond to the actual or anticipated blood pressure demand event by delivering neuromodulation energy using a second parameter set to change the blood pressure.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 21, 2019
    Inventors: Craig Stolen, Bryan Allen Clark, Manda L. Keller-Ross, Ninitha Margret Julfiya Asirvatham-Jeyaraj, Daniel P. Chantigian
  • Publication number: 20190351235
    Abstract: A system for stimulating a sympathetic chain includes an electrode assembly that is configured to attach to a bone in proximity to a targeted portion of the sympathetic chain. The electrode assembly includes a cathode and an anode. The system also includes a power supply connected to the electrode assembly and configured to deliver power to the electrode assembly. The electrode assembly generates an electrical field between the cathode and the anode when power is delivered to the electrode assembly. The electrical field reaches the targeted portion of the sympathetic chain to provide electrical stimulation to the targeted portion of the sympathetic chain.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 21, 2019
    Applicant: Washington University
    Inventors: Eric Leuthardt, Daniel Moran, Matthew MacEwan, Amy Moore, Paige Cloonan, Yidan Qin, Christopher Zhang, Ashwin Kamath, Wilson Ray
  • Publication number: 20190351236
    Abstract: An implantable medical device (IMD) may include a housing having a proximal end and a distal end and a set of one or more electrodes connected to but spaced apart from the housing. The IMD may further include a controller disposed within the housing, wherein the controller is configured to sense cardiac electrical signals, and deliver electrical stimulation pulses via the first set of one or more electrodes. In some embodiments, a first portion of the housing is configured to be disposed at least partly within a coronary sinus of a patient's heart and a second portion of the housing is configured to be disposed at least partly within a right atrium of the patient's heart.
    Type: Application
    Filed: July 30, 2019
    Publication date: November 21, 2019
    Applicant: CARDIAC PACEMAKERS, INC.
    Inventor: Brendan E. Koop
  • Publication number: 20190351237
    Abstract: Methods and systems for treating cardiac malfunction are disclosed, which according to an embodiment, may involve delivering a stimulation pattern of stimulation pulses to at least one cardiac chamber of a heart, with at least one of the stimulation pulses having a first stimulation setting configured to reduce at least one of end systolic volume (ESV) and end diastolic volume (EDV) in the heart and at least one of the stimulation pulses having a second stimulation setting different from the first stimulation setting, and with the stimulation pattern being configured to reduce the at least one of end systolic volume (ESV) and end diastolic volume (EDV) by at least 5% and maintain the at least one of end systolic volume (ESV) and end diastolic volume (EDV) on average at such reduced volume for a time period of at least one hour.
    Type: Application
    Filed: June 5, 2019
    Publication date: November 21, 2019
    Inventors: Yuval Mika, Darren Sherman, Daniel Burkhoff
  • Publication number: 20190351238
    Abstract: An example of a method embodiment may include receiving a user programmable neural stimulation (NS) dose for an intermittent neural stimulation (INS) therapy, and delivering the INS therapy with the user programmable NS dose to an autonomic neural target of a patient. Delivering the INS therapy may include delivering NS bursts, and delivering the NS bursts may include delivering a number of NS pulses per cardiac cycle during a portion of the cardiac cycles and not delivering NS pulses during a remaining portion of the cardiac cycles. The method may further include sensing cardiac events within the cardiac cycles, and controlling delivery of the user programmable NS dose of INS therapy using the sensed cardiac events to time delivery of the number of NS pulses per cardiac cycle to provide the user programmable NS dose. The user programmable NS dose may determine the number of NS pulses per cardiac cycle.
    Type: Application
    Filed: July 30, 2019
    Publication date: November 21, 2019
    Inventors: David J. Ternes, Jason J. Hamann, Stephen B. Ruble, Juan Gabriel Hincapie Ordonez, Manfred Franke
  • Publication number: 20190351239
    Abstract: An electronic medical device includes a first portion, with the first portion including a first insertion hole and an external surface. The first insertion hole is to removably receive an elongate element. The external surface of the first portion comprises a first position indicator, which is located to be visibly juxtaposed relative to a first operative element of the elongate element when the elongate element is fully inserted in the first insertion hole. In some instances, the position indicator may serve a dual function as a vent.
    Type: Application
    Filed: June 1, 2018
    Publication date: November 21, 2019
    Applicant: INSPIRE MEDICAL SYSTEMS, INC.
    Inventors: Kevin Verzal, John Rondoni
  • Publication number: 20190351240
    Abstract: An RF switchable filter feedthrough housed inside an AIMD is described. The RF switchable filter feedthrough includes an RF switch having a switching pole that is configured to be controlled by an AIMD control signal to switch between first and second throw position. In the first throw position, a conductive leadwire hermetically sealed to and disposed through an insulator is electrically connected to a two-terminal MLCC chip capacitor which in turn is electrically connected to the ferrule. In the first throw position, EMI energy imparted to a body fluid side implanted lead is diverted to the housing of the AIMD by the chip capacitor. In the second throw position, the conductive leadwire is electrically connected to an RF source disposed inside the AIMD housing. In the second throw position, by measuring a reflective return signal from the RF source it can be determined whether the implanted lead has a defective lead conductor.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 21, 2019
    Inventors: Robert A. Stevenson, Keith W. Seitz
  • Publication number: 20190351241
    Abstract: Described are implantable pouch products having a segmental lamination structure that provides an interior pocket for receiving a medical device, for example an electronic medical device such as a cardiac pacemaker or defibrillator. Also described are methods for making and using such products.
    Type: Application
    Filed: January 18, 2019
    Publication date: November 21, 2019
    Applicant: Cook Biotech Incorporated
    Inventor: Tyler Novak
  • Publication number: 20190351242
    Abstract: An apparatus configured to control transmission of wireless energy supplied to an electrically operable medical device adapted to be implanted in a mammal patient, is disclosed. The apparatus comprises an external energy source, an internal energy receiver located inside the patient and being adapted to receive the wireless energy, a stabilizing unit adapted to stabilize the wirelessly received energy in the electrically operable medical device, and a control unit comprising at least one of an internal control unit and an external control unit.
    Type: Application
    Filed: May 28, 2019
    Publication date: November 21, 2019
    Inventor: Peter Forsell
  • Publication number: 20190351243
    Abstract: A proximity-based security mechanism can control access to the programming interface of an implanted medical device. The security mechanism prevents unauthorized remote access to the programming interface by hackers or other hostile individuals, securing the safety of the subject. The system also allows the subject or other responsible person to activate the programming interface when changes to the operation of the implanted medical device are needed. In one example, a security interface is operable to detect, while implanted in the subject, an activation signal produced in close proximity to the subject, and activate the programming interface in response to the activation signal so that the implantable medical device can receive the programming instructions. A proximity-based security mechanism can be a dedicated device, or can be implemented in a programmable computing device such as a smartphone or other mobile computing device.
    Type: Application
    Filed: May 17, 2018
    Publication date: November 21, 2019
    Inventors: Sheldon Meredith, Peter Hardie, William C. Cottrill
  • Publication number: 20190351244
    Abstract: A trial stimulation system includes a disposable trial electrical stimulator that, in some examples, is sterilized for a single use in a stimulation trial of one patient. Additionally, systems for securing a disposable trial stimulator to the body of a patient are described, which may function to improve the durability of the system during the trial period and reduce the risk of damage or malfunction to the system due to lead/electrode dislocation and/or off-label uses like showering or bathing with the trial stimulator still secured to the body.
    Type: Application
    Filed: August 2, 2019
    Publication date: November 21, 2019
    Inventors: John Shishilla, Kathryn Pederson, Mukul Jain, Nicholas S. Mairs
  • Publication number: 20190351245
    Abstract: A communications module adapted for use with a defibrillator, comprising a power supply system configured to supply power to the communications module, a power connector adapted for connection to the defibrillator to provide power from the communications module to the defibrillator, a power switch connected between the power supply system and the power connector to transmit power from the power supply system to the power connector, a data connector adapted for connection to the defibrillator to transfer defibrillator data between the defibrillator and the communications module, and a processor configured to control the power switch to provide power from the communications module to the defibrillator to enable the transfer of the defibrillator data between the defibrillator and the communications module.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 21, 2019
    Inventors: Johnny ANDERSON, Dymphna Mary DONAGHY
  • Publication number: 20190351246
    Abstract: A medical device is configured to deliver an electrical stimulation pulse to a heart of a patient, determine a pre-stimulation cardiac event amplitude prior to delivering the electrical stimulation pulse and adjust a cardiac event sensing threshold according to a first post-stimulation decay sequence in response to the electrical stimulation pulse delivery. The first post-stimulation decay sequence is controlled by a sensing module of the medical device according to a first set of sensing control parameters including at least one sensing control parameter based on the pre-stimulation cardiac event amplitude.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 21, 2019
    Inventors: Robert W. Stadler, Jian Cao
  • Publication number: 20190351247
    Abstract: The subject matter of the invention is a therapeutic device in the form of a cylindrical chamber which comprises a hyperbaric chamber, LED matrices (5) and inductive coil rings (10, 11, 12, 13), constructed in one inseparable set in the form of a chamber of 200-280 cm in length and diameter of the round cylinder (70-130 cm).
    Type: Application
    Filed: December 20, 2017
    Publication date: November 21, 2019
    Inventor: Aleksander Romuald SIERON
  • Publication number: 20190351248
    Abstract: A transcranial magnetic stimulation (TMS) treatment system is provided. The system includes a sensor device that senses EEG signals from a subject through one or more leads and a server device configured to receive EEG data corresponding to the subject. The server includes an analysis module configured to process the EEG data and determine a personalized resonant brain frequency and a minimum neuronal activation threshold of the subject based at least in part on EEG data corresponding to one or more leads of the sensor device. The analysis module is also configured to determine a TMS treatment protocol where the treatment protocol includes at least a frequency based on the personalized resonant brain frequency and an amplitude based on the minimum neuronal activation threshold. The system also includes a treatment device configured to deliver a TMS treatment to the subject based on the TMS treatment protocol received from the server.
    Type: Application
    Filed: July 30, 2019
    Publication date: November 21, 2019
    Inventors: Kevin Timothy MURPHY, Michael Sean MURPHY
  • Publication number: 20190351249
    Abstract: Embodiments of the invention include methods of treating a patient with physiological responses arising from an injury or condition, such as post-operative pain, traumatic brain injury, and cognitive defects. These treatment methods can include the steps of generating a pulsed electromagnetic field from a pulsed electromagnetic field source which is configured to simultaneously increase the rate of ion-dependent signaling, such as CaM/NO/cGMP signaling and to minimize the rate of inhibition of such signaling by natural compounds and applying the pulsed electromagnetic field in proximity to a target region affected by the injury or condition for a first treatment interval followed by an inter-treatment period with no electromagnetic field between treatment intervals to reduce a physiological response to the injury or condition.
    Type: Application
    Filed: June 4, 2019
    Publication date: November 21, 2019
    Applicant: Endonovo Therapeutics, Inc.
    Inventor: Arthur A Pilla
  • Publication number: 20190351250
    Abstract: A cancer treatment apparatus including a magnetic field generator that generates a magnetic field of 100 kHz to 300 kHz to be applied to affected tissues.
    Type: Application
    Filed: November 22, 2017
    Publication date: November 21, 2019
    Inventors: Yoshihiro ISHIKAWA, Masanari UMEMURA, Taisuke AKIMOTO
  • Publication number: 20190351251
    Abstract: A cap to be placed on a head of a device for treating the skin of a user includes an inner part to be removably attached to the head of the device, an outer part to be placed against the skin of the user and an interior disposed between the inner and outer parts. A product is disposed in the interior for application to the skin of the user and a covering, such as a membrane which is disposed on the outer part or a sterilized pack, is removable before use. An assembly having the device and the cap is also provided.
    Type: Application
    Filed: May 15, 2018
    Publication date: November 21, 2019
    Inventors: MOTI SHENFARBER, GENNADIY BERINSKY
  • Publication number: 20190351252
    Abstract: An apparatus and method is provided for irradiating a portion of a patient's scalp with light. The apparatus includes a source of light including one or more wavelengths in a range of about 630 nanometers to about 1064 nanometers. The apparatus further includes an output optical element in optical communication with the source. The output optical element includes an emission surface configured to emit a light beam having a cross-sectional area greater than about 2 cm2 at the emission surface of the output optical element and having a time-averaged irradiance in a range of about 10 mW/cm2 to about 10 W/cm2 across the cross-sectional area. The apparatus further includes a thermally conductive portion configured to be placed in thermal communication with the irradiated portion of the patient's scalp and to remove heat from the irradiated portion of the patient's scalp at a rate in a range of about 0.1 Watt to about 5 Watts.
    Type: Application
    Filed: June 19, 2019
    Publication date: November 21, 2019
    Inventors: Luis De Taboada, Jackson Streeter, Scott Bradley, Scott Delapp, Terry McNeill
  • Publication number: 20190351253
    Abstract: An apparatus for tissue regeneration is provided. The apparatus comprises means for generating at least one laser pulse comprising a wavelength; and means for directing the at least one laser pulse onto a tissue surface of a human or animal body, wherein the means for generating comprises control means to ensure that a sum of the pulse energies of the at least one laser pulse is selected so that the corresponding fluence on the tissue surface heats the tissue surface up to a maximal temperature Tmax between 70° C. and a tissue boiling temperature Tb. Further, the means for generating of the apparatus are adapted so that a delivery time ted of the at least one laser pulse (during which the second half of the pulse energy is delivered) is sufficiently short so that, given the wavelength and thus a corresponding penetration depth ? of the at least one laser pulse, a thermal exposure time texp of the tissue surface is shorter than 900 microseconds.
    Type: Application
    Filed: May 14, 2019
    Publication date: November 21, 2019
    Inventors: Matjaz Lukac, Franci Bajd, Marko Kazic, Zdenko Vizintin, Tadej Perhavec
  • Publication number: 20190351254
    Abstract: A system that generates a three-dimensional model of a tissue surface, for example the inner surface of the heart from two-dimensional image data slices. On this surface, one or more pattern lines are drawn, e.g., by a physician using a user interface, to designate desired lesion(s) on the surface. From the pattern lines, a three-dimensional volume for a lesion can be determined using known constraints. Advantageously, the series of boundaries generated by the three-dimensional volume may be projected back onto the individual CT scans, which then may be transferred to a standard radiosurgical planning tool. A dose cloud may also be projected on the model to aid in evaluating a plan.
    Type: Application
    Filed: November 19, 2018
    Publication date: November 21, 2019
    Applicant: CyberHeart, Inc.
    Inventors: Thilaka Sumanaweera, Ed Gardner, Oliver Blanck, Tao Cai, Darrin Uecker, Patrick Maguire
  • Publication number: 20190351255
    Abstract: An immobilization apparatus having at least one or more straps that engage a surface; wherein at least one of the straps comprises a force gauge to determine the amount of force applied to a patient immobilized with said straps; wherein the position of the patient is replicable for treatment of radiation and other head or neck treatments.
    Type: Application
    Filed: January 22, 2018
    Publication date: November 21, 2019
    Applicant: Thomas Jefferson University
    Inventors: Hyun Kim, Voichita Bar Ad, Amy Taylor, Shivank Garg
  • Publication number: 20190351256
    Abstract: A positioning stud for radioactive therapy includes a stud rod, a stud tip, and an insulating component. The insulating component is connected between the stud rod and the stud tip, and is used to prevent contact between the stud rod and the stud tip.
    Type: Application
    Filed: January 24, 2017
    Publication date: November 21, 2019
    Inventor: Qi GAO
  • Publication number: 20190351257
    Abstract: A beam shaping assembly (10) used in a neutron capture system and capable of changing an irradiation range of a neutron beam. The beam shaping assembly includes: a beam inlet (11), a target (12), a moderator (13) adjoining the target (12), a reflector (14) surrounding the moderator (13), a thermal neutron absorber (15) adjoining the moderator (13), a radiation shield (16) arranged inside the beam shaping assembly (10), and a beam outlet (17). The beam shaping assembly (10) further includes replacement components (21, 22) that can be attached to and detached from the beam shaping assembly (10) to change the irradiation range of the neutron beam.
    Type: Application
    Filed: July 15, 2019
    Publication date: November 21, 2019
    Inventors: Wei-Lin CHEN, Yuan-Hao Liu
  • Publication number: 20190351258
    Abstract: The invention comprises a method and apparatus for steering/scanning charged particles, comprising: a double dipole scanning system, comprising: (1) a beam path chamber comprising an entrance side and an exit side, the entrance side comprising a smaller area than the exit side; (2) a first dipole magnet, the first dipole magnet comprising a first coil and a third coil on first opposite sides of the beam path chamber; and (3) a second dipole magnet, the second dipole magnet comprising a second coil and a fourth coil on second opposite sides of the beam path chamber, the beam path chamber further comprising a truncated square/rectangle pyramid shape, the smaller entrance side of the charged particles comprising a top of the truncated pyramid shape, the exit side of the charged particles comprising a larger bottom of the truncated pyramid shape.
    Type: Application
    Filed: July 30, 2019
    Publication date: November 21, 2019
    Inventors: Faye Hendley Elgart, Nick Ruebel, Mark R. Amato, Nandish Desai, W. Davis Lee
  • Publication number: 20190351259
    Abstract: The invention comprises a method and apparatus for reducing a kinetic energy of positively charged particles, comprising the steps of: (1) transporting the positively charged particles from an accelerator into an exit nozzle system along a beam line; (2) providing a first chamber of the exit nozzle system, the first chamber comprising: an incident side comprising an incident aperture, an exit side comprising an exit aperture, and a beam path of the positively charged particles from the incident aperture to the exit aperture; (3) filling the beam path in the chamber with a liquid; and (4) using the liquid to reduce the kinetic energy of the positively charged particles. The kinetic energy dissipater is optionally used in combination with a proton therapy cancer treatment system and/or a proton tomography imaging system.
    Type: Application
    Filed: July 30, 2019
    Publication date: November 21, 2019
    Inventors: W. Davis Lee, Mark R. Amato
  • Publication number: 20190351260
    Abstract: An apparatus for controlling the angular direction of energy emitted from a plurality of energy delivery devices. The apparatus includes a plurality of rods, each rod mechanically coupled to one of the energy delivery devices, to a stationary plate, and to a moveable plate. The stationary plate includes holes that are configured to receive a portion of a first rotatable joint that is mechanically coupled to each rod. The moveable plate includes holes that are configured to receive a portion of a second rotatable joint, the second rotatable joint slidingly engaging a portion of the respective rod. The angle of each rod changes when the moveable plate is moved in any direction with respect to the stationary plate. Changing the rod angle changes the angular direction of the energy emitted from the energy delivery devices such that the energy passes through an intended focal position.
    Type: Application
    Filed: May 16, 2018
    Publication date: November 21, 2019
    Inventor: Aaro Tuominen
  • Publication number: 20190351261
    Abstract: During a focused-ultrasound or other non-invasive procedure, regions of change within a target region are monitored, and images of the target region are updated with partial images encompassing only the regions of change.
    Type: Application
    Filed: May 18, 2018
    Publication date: November 21, 2019
    Inventor: Yoav LEVY
  • Publication number: 20190351262
    Abstract: Methods, kits and structures are disclosed for providing a desired protective and/or visual effect to natural or artificial nails. One method comprises applying a base coat to at least part of an outer surface of the nail substrate; providing a flexible support having disposed, on a surface thereof, a monolayer of metallic-looking particles of at least one metallic-looking pigment; and transferring the monolayer from the flexible support to an outer surface of the applied base coat, so as to form a coat of metallic looking particles on the nail substrate.
    Type: Application
    Filed: January 11, 2018
    Publication date: November 21, 2019
    Applicant: LANDA LABS (2012) LTD
    Inventors: Benzion LANDA, Sagi ABRAMOVICH, Galia GOLODETZ, Dan AVITAL
  • Publication number: 20190351263
    Abstract: A denture cleaning wipe is a sheet made of a flexible material with a gripping surface opposite a cleaning surface. A first finger pocket and a second finger pocket are each coupled to the gripping surface so that a first portion of an outer edge of the first and second finger pockets are coupled to the sheet and a second portion of the outer edge of the first and second finger pockets are detached from the sheet defining entrances into the first and second finger pockets. The first finger pocket and the second finger pocket are spaced apart and oriented so that the entrances are facing each other.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 21, 2019
    Inventor: Ricky Allen Pace
  • Publication number: 20190351264
    Abstract: A fall-protection apparatus with a friction-braking system comprising a handle that is disconnectably connected to a braking cam so that when the handle is moved from a braking position to a non-braking position the braking cam is pivotally moved from a braking configuration to a non-braking configuration, and so that when the handle is moved to a disconnecting position the connection between the handle and the braking cam is disconnected.
    Type: Application
    Filed: December 7, 2017
    Publication date: November 21, 2019
    Inventor: Oscar Ratalino
  • Publication number: 20190351265
    Abstract: A panel for covering a supply channel in a passenger cabin of a vehicle including a mounting surface facing the passenger cabin while the panel covers the supply channel. The panel is elongated in a longitudinal direction and adapted for mounting passenger supply units. The mounting surface includes spaced openings arranged along a longitudinal direction of the panel, wherein each opening includes a connector assembly for a passenger supply unit. The panel includes a mount securing passenger supply units. The mounting surface comprises extended areas for providing support in opposing lateral directions to passenger supply units mounted to the panel.
    Type: Application
    Filed: July 11, 2019
    Publication date: November 21, 2019
    Inventor: Christian Riedel
  • Publication number: 20190351266
    Abstract: The aircraft emergency oxygen supply system includes one or more sources of supplemental breathable oxygen, one or more inlet valves for one or more breathing devices, connected to the inlet valves, and one or more cabin air pressure transducers. A pressure controller controls the inlet valves in response to the one or more cabin air pressure transducers. One or more second pressure transducers may connected to conduits downstream of inlet valves to be monitored, and the pressure controller may also control operation of the inlet valves in response to the one or more second pressure transducers.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 21, 2019
    Applicant: BE Intellectual Property, Inc.
    Inventor: James C. Cannon
  • Publication number: 20190351267
    Abstract: Embodiments of the present disclosure are directed to a vent monitoring system that includes a first sensor configured to provide feedback indicative of an amount of a substance accumulated in the vent, a second sensor configured to provide feedback indicative of a temperature in the vent, and a control system communicatively coupled to the first sensor and the second sensor, where the control system is configured to generate a notification when the feedback from the first sensor exceeds a first target level and when the feedback from the second sensor exceeds a second target level.
    Type: Application
    Filed: September 12, 2018
    Publication date: November 21, 2019
    Inventors: Jill L. Gantos, Peter M. Schmitz