Abstract: Polymers, hydrogels, and thermochromic agents, including products embodying them, methods of using them, and processes for making them. In certain embodiments, temperature therapy packs which utilize thermochromic agents integrated into solid, semi-solid, or liquid hydrogels. In preferred (but optional) embodiments, the thermochromic agents are integrated into the composition used as the temperature exchange material of the therapy pack. In certain other embodiments, methods of using the thermochromic integrated temperature exchange materials, or processes for manufacturing such thermochromic integrated temperature exchange materials and/or methods or processes for manufacturing or using thermal packs embodying such materials. In certain particularly preferred embodiments, novel polymer compositions and/or processes for making polymers, which improve product durability or longevity and/or which improve use cycles or usage times.

Abstract: An eye ailment treatment apparatus includes a case having an outer wall that has a front end and a rear end opposite the front end, the outer wall defining an interior area and having an outlet port at the front end. A water reservoir is positioned in the interior area and in operable communication with the outlet port. A pump is operably coupled to the water reservoir for pumping water from the water reservoir to the outlet port when actuated. An actuator is positioned on the outer wall and operably coupled to the pump for actuating the pump when operated. A treatment head is in fluid communication with the outlet port, the treatment head having an external surface constructed of a soft material for contact with a user's eye and having an unvented internal chamber that includes a exothermal material that generates heat when mixed with water.

Abstract: An implantable medical device is described. The implantable medical device includes an anti-condensation filler that is highly permeable to a predetermined class of small molecules, such as oxygen. The implantable medical device includes a small molecule discharge bag that is permeable to the small molecule, and a cannula that connects an interior of the small discharge bag to the anti-condensation filler. In operation, small molecules are collected and transported through the anti-condensation filler to the cannula for diffusion through the small molecule discharge bag. Even when this device is implanted in a high humidity and temperature gradient environment, the anti-condensation filler prevents condensation, such as water condensation.

Abstract: Graphical user interface system and method for displaying and controlling a surgical device, such as a device used in phacoemulsfication procedures. A graphical user interface is displayed on a display screen and includes one or more representations of operating parameters, such as aspiration rate, vacuum, and power that are used to control the surgical device. A parameter is adjusted by moving a portion of a representation from a first location on the display screen to a second location on the display screen to change the operating parameter and control the surgical device.

Abstract: A design for dynamically adjusting parameters applied to a surgical instrument, such as an ocular surgical instrument, is presented. The method includes detecting surgical events from image data collected by a surgical microscope focused on an ocular surgical procedure, establishing a desired response for each detected surgical event, delivering the desired response to the ocular surgical instrument as a set of software instructions, and altering the surgical procedure based on the desired response received as the set of software instructions.

Abstract: A method of treating glaucoma in an eye utilizing an implanted shunt having an elastomeric plate and a non-valved elastomeric drainage tube. The plate is positioned over a sclera of the eye with an outflow end of the elastomeric drainage tube open to an outer surface of the plate. An inflow end of the drainage tube tunnels through the sclera and cornea to the anterior chamber of the eye. The drainage tube collapses upon initial insertion within an incision in the sclera and cornea, or at a kink on the outside of the incision, but has sufficient resiliency to restore its patency over time. The effect is a flow restrictor that regulates outflow from the eye until a scar tissue bleb forms around the plate of the shunt. The plate desirably has a peripheral ridge and a large number of fenestrations, and a longer suturing tab extending from one side of the plate to enhance visibility and accessibility when suturing the shunt to the sclera.

Abstract: An ocular implant delivery system is provided with a number of features. In some embodiments, the delivery system comprises a rotation mechanism configured to rotate and orient a cannula of the system, and an advancement mechanism configured to advance and retract an ocular implant through the delivery system and into an eye of a patient. In some embodiments, the cannula is sized and configured to be inserted into Schlemm's canal of the eye. The ocular implant is configured to maintain its orientation within the delivery system as the cannula is rotated. In some embodiments, the ocular implant automatically disengages the delivery system when it is advanced beyond a distal tip of the delivery system. Methods of implanting an ocular implant are also provided.

Abstract: Shunt devices and a method for continuously decompressing elevated intraocular pressure in eyes affected by glaucoma by diverting excess aqueous humor from the anterior chamber of the eye into Schlemm's canal where post-operative patency can be maintained with an indwelling shunt device which surgically connects the canal with the anterior chamber. The shunt devices provide uni- or bi-directional flow of aqueous humor into Schlemm's canal.

Abstract: A method and system perform an ophthalmic procedure on an eye having an optical path from the lens to the retina. An image of at least part of the eye is received in a data processing unit. The image includes the optical path. The data processing unit determines keep out zone(s) and identifies undesirable feature(s) based on the image. The keep out zone(s) include the retina. The data processing unit also selects one of the undesirable feature(s) for removal. At least part of the undesirable feature is outside of the keep out zone(s). Confirmation for removal of the undesirable feature is received in the data processing unit. In response to receiving the confirmation, a control unit controls a laser to perform laser removal the at least the portion of the undesirable feature without targeting any portion of the keep out zone(s).

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a flexible housing tube having a flexible housing tube distal end and a flexible housing tube proximal end, an actuation mechanism control of the handle, and an optic fiber disposed within an inner bore of the handle and within the flexible housing tube. An actuation of the actuation mechanism control may be configured to gradually curve the flexible housing tube. A gradual curving of the flexible housing tube may be configured to gradually curve the optic fiber. An actuation of the actuation mechanism control may be configured to gradually straighten the flexible housing tube. A gradual straightening of the flexible housing tube may be configured to gradually straighten the optic fiber.

Abstract: A planning apparatus for generating control data for an eye surgery treatment device which creates at least one cut surface in the cornea using a laser device. The planning apparatus includes a calculation tool for determining the at least one cut surface in the cornea. The calculation tool determines the at least one cut surface in the cornea based on data from a refractive correction and generates a set of control data that control the laser device for the at least one cut surface in the cornea. The at least one cut surface in the cornea includes an edge and optically effective areas. The calculation tool determines the at least one cut surface in the cornea such the at least one cut surface in the cornea is deeper at the edge than in the optically effective areas.

Abstract: A method for forming an incision in an eye, the method including performing a first pass of a first laser beam along a path within an eye, wherein after completion of the first pass there exists a residual uncut layer at an anterior surface of a cornea of the eye. The method further including performing a second pass of a second laser beam only along a portion of the path that contains the residual uncut layer, wherein after completion of the second pass, the residual uncut layer is transformed into a full complete through surface incision.

Abstract: An ophthalmic laser treatment system and method providing for a liquid optical interface (LOI) with a patient eye surface (PES) using an elliptical ocular suction ring (OSR) is disclosed. A disposable ocular patient interface (OPI) provides for simultaneous differential vacuum mating of the PES, OSR, OPI, and an optical window retainer (OWR). The PES, OSR, OPI, and OWR form an enclosed volume in which liquid may be interjected to cover the PES during laser treatment. A vacuum suction pump (VSP) provides controlled vacuum to the OPI ensuring proper differential vacuum mating (DVM) between the PES, OSR, OPI, and OWR during laser treatment. The OWR connects to a laser objective bracket (LOB) via an ocular force sensor (OFS) and an optical separator bracket (OSB). The OFS senses applied pressure to the PES and provides data to a computerized control device (CCD) that limits applied pressure to the PES during laser treatment.

Abstract: A negative pressure wound therapy (NPWT) dressing includes a wick configured for placement over an incision. A transfer assembly includes a compressible, porous core with a permeable cover placed over the core. The transfer assembly is positioned on the wick in fluidic contact and is covered by a dressing cover, which is configured for adhesive attachment to the patient around the incision. A drain slip including a proximal end configured for placement in the incision extends through the wick and the transfer assembly and is configured for connection to a negative pressure source. A NPWT method includes steps of draining a closed incision using negative pressure applied to a drain slip.

Abstract: A flexible adhesive kinesiology/physio tape adapted to produce heat from the exothermic oxidation when exposed to air. The inventive tape includes a layer of porous material with iron and salt disposed therein. In the best mode, the layer is flexible and self-adhesive. A layer of plastic is included to inhibit oxidation prior to application and use. In a preferred embodiment, the inventive flexible adhesive tape includes a first layer of flexible adhesive high quality porous fabric; a second layer of flexible adhesive high quality porous fabric; and the layer of flexible exothermic material, sandwiched between the first and second layers. The third layer can be fabricated with cellulose, iron, water, activated carbon, vermiculite and salt or fabricated with a mixture of chemical salt in dry crystal form with water. Or any other chemical mixture that creates an exothermic reaction.

Abstract: The present invention provides an underpants-type disposable diaper that has pleats formed in an outer body, which vertically and straightly extend, is excellent in appearance and air permeability, and is excellent in drawing preventing performance of a resilient and elastic member.

Abstract: A method for indicating and alarming about wet level of a diaper involves using a humidity sensor to perform relative humidity detection on the diaper, when the detected relative humidity is below 50% rh˜60% rh, showing the diaper's wet level as 0% rh, and when the detected relative humidity is 85% rh˜95% rh or more, showing the diaper's wet level as 100% rh, wherein functional conversion is performed to convert the relative humidity ranging between 60% rh and 85% rh˜95% rh proportionally into the diaper's wet level between 0% rh and 100% rh.

Abstract: A diaper insert has a liquid impermeable external surface, an inner surface, and an absorbency area adjacent the inner surface. The absorbency area has at least one absorbent layer. The diaper insert has a distal end, an attachment end, and a midsection between the distal end and attachment end. The midsection has opposing sides that are in general mirror images to one another about a vertical line. A width of the midsection is less than or equal to a width of the attachment end, and a width of the midsection is less than or equal to a width of the distal end.

Abstract: In one embodiment, taped and pant articles of the present disclosure may comprise first and second chassis and first and second belt flaps that are at least substantially identical.

Abstract: The present invention relates to a reel for a plaster strip roll with one or two side discs and/or a cover/protective ring for a plaster strip roll, which optionally has a tear-off edge, as well as the production thereof. The reel or the cover/protective ring, respectively, comprises an antimicrobially effective substance, wherein, on the outer surface of the reel or of the cover/protective ring, respectively, there is contact between the antimicrobially effective substance and the environment.

Abstract: The present disclosure may relate to a wheelchair that includes a first centerless wheel assembly including a drive roller guide assembly and three other roller guides, and a first drive mechanism coupled to the first drive roller guide assembly to drive the first centerless wheel assembly. The wheelchair may also include a second centerless wheel assembly including a drive roller guide assembly and three additional roller guides, and a second drive mechanism coupled to the second drive roller guide assembly to drive the second centerless wheel assembly.

Abstract: A gravity reactive braking system comprises a housing connected to a structural element of a manually powered wheeled unit; a guide wheel having a first sector of radially protruding elements positionable in drivable contact with a main wheel periphery, and a second sector with a circular periphery of a shorter radial length than the first sector; a plate configured with a cammed surface; a height adjustment unit; and a follower element connected to a brake assembly cable and pivotably mounted onto the housing, for movably engaging a plate periphery. The guide wheel is rotatable in a rotational direction opposite to the main wheel's rotational direction when the radially protruding elements are positioned in drivable contact with the main wheel periphery following suitable manipulation of the height adjustment unit, and is indexable a predetermined angle until a desired region of the guide wheel is in contact with the main wheel periphery.

Abstract: A back support for use with a chair includes a first support, a second support spaced from the first support, and an adjustable support extending between the first and second supports, the adjustable support includes a cable and an adjustable tensioning assembly operably connected to the cable, wherein in response to actuation of the adjustable tensioning assembly a length of exposed cable changes.

Abstract: A person support apparatus includes a support adapted to support thereon an occupant of the person support apparatus and a sensor configured to detect an ambient air characteristic. The sensor generates an output signal based on the detected characteristic and communicates the output signal to a controller. The controller is configured to receive the output signal from the sensor and determine a usability status of the person support apparatus. The usability status may include an indication that the person support apparatus is ready for use by an occupant, whether a potential hazard exists for an occupant of the person support apparatus, a cleaning status of the person support apparatus, or a location of the person support apparatus.

Abstract: A patient support apparatus comprises a base, a support frame, and a patient support deck. The patient support deck comprises articulating deck sections, such as a leg section and a foot section pivotally coupled to the leg section. A support link is arranged to support the foot section relative to the support frame. A leg section actuator is configured to move the leg section between a lowered position and one or more raised positions. A foot section adjustment device is configured to move the support link in order to move the foot section relative to the leg section. The support link has a first link end pivotally coupled to the foot section and a second link end slidably coupled to the support frame.

Abstract: A sleep system comprises at least one mattress including a first sleep area for a first occupant, the first sleep area including a first section for a portion of a body of the first occupant, and a second sleep area adjacent to the first sleep area for a second occupant, the second sleep area including a second section for a portion of a body of the second occupant, an articulation system for articulating the first section and the second section, a first user controller configured to communicate with the articulation system in order to control articulation of the first section, and a second user controller configured to communicate with the articulation system in order to control articulation of the second section, wherein the first user controller is further configured to communicate with the articulation system in order to move the second section into a predetermined position.

Abstract: Completely self-contained and self-supported mobile isolation and containment unit (ICU) facilities are disclosed that can be transported on roads and highways to a location in need of an isolation facility and rapidly deployed to provide isolation and treatment. In some embodiments, exemplary ICUs can safely provide isolation and treatment to a level that meets or exceeds “bricks and mortar” hospital isolation and containment facilities and any applicable regulations. In some examples, the mobile ICUs include sophisticated heating ventilation and air Conditioning (HVAC) systems that can separately maintain areas within the facility at different levels of pressure to ensure contaminated air does not escape the facility. And the mobile ICUs may also incorporate a multiple-vestibule with airlock design for ensuring safe entry and exit from the facility. The mobile ICUs disclosed herein may also include automated decontamination systems for disinfecting and/or sterilizing spaces within the facility.

Abstract: A trolley (10) for a medical waste container (12) is provided for use in a medical treatment facility such as an operating theatre or other hospital or medical environment. A cart (100) is provided for transporting a collection of medical waste containers (12) throughout a medical treatment facility.

Abstract: An articulated chin rest is assembly is provided for supporting the chin of a patient under monitored anesthesia care, sedation, general anesthesia, or other medical procedure to ensure that their airway is unobscured. The assembly may comprise a clamp adaptable to grip a variety of structures, a first and a second length of rigid material sequentially and rotatably connected to the clamp, and a chin rest finally rotatably connected to the second length of rigid material. Means for rotatably linking the clamp, first and second lengths of rigid material, and chin rest allow each element to rotate in three dimensional space so that the assembly mechanically mimics, and is ultimately usable in place of, an anesthesiologist's hand for tilting the patient's head and securely supporting the patient's chin.

Abstract: A patient support apparatus for spine surgery includes first and second lift columns. A patient support frame extends between the first and second lift columns. The patient support frame has a first section to support a torso of a patient and a beam that extends from the first section. The beam is coupled to a foot end region of the first section about midway between opposite sides of the first section. A first set of leg supports are located adjacent a first side of the beam and a second set of leg supports are located adjacent a second side of the beam. The first and second sets of leg supports are independently movable relative to the beam and relative to the first section to support the legs of the patient in a plurality of positions.

Abstract: Compression systems and methods for tightening a garment and/or applying a pressure through the garment may include a garment, a lacing system, and a tightening apparatus. The compression system may be used for tightening the garment about a portion of a body and/or applying pressure to a portion of the body by pressure applying regions of the garment. The lacing system may include lacing guide and at least one lace guided by the lacing guide members. The tightening apparatus may be coupled to the at least one lace and may be configured to apply tension on the at least one lace to tighten the garment about the portion of the body.

Abstract: A body massaging apparatus is described that includes a support frame, a generally horizontal neck massage bar mounted to the support frame, and a generally horizontal back massage bar mounted to the support frame at a position beneath and in front of the neck massage bar, with the area bounded by the left front support member, right front support member, neck massage bar and back massage bar being an open space. Methods of making and using the apparatus also are disclosed.

Abstract: A powered exoskeleton includes a leg part and a foot part. The foot part includes a foot bottom plate and a foot bottom plate driving wheel. The foot bottom plate includes a first surface and a second surface opposite to each other; and the foot bottom plate driving wheel is connected below the leg part. The foot bottom plate is movably connected to the foot bottom plate driving wheel and capable of being turned over relative to the foot bottom plate driving wheel. In the walking mode, the foot bottom plate is turned over till the first surface of the foot bottom plate faces upward and is connected below the foot bottom plate driving wheel; and in the wheeled movement mode, the foot bottom plate is turned over till a second surface of the foot bottom plate faces upward and is connected above the foot bottom plate driving wheel.

Abstract: A robotic limb rehabilitation apparatus and system for a lower limb in a human being is disclosed. The apparatus comprises of a mobile-frame, dynamic weight unloading mechanism and lower extremity exoskeleton device. The mobile-frame structure is constructed using first and second vertical structural support members connected by a horizontal cross bar/beam to which a boom arm assembly is attached. During the rehabilitation exercises the user is secured with a harness and lower extremity exoskeleton device for safe movements. An intelligent algorithm, embedded onto a dedicated processor, actuates various motors to execute the prescribed exercises, while the sensors provide dynamic feedback for corrective measures to control the exercise routine.

Abstract: Apparatus and associated methods relate to a wearable compression therapy system for ambulatory therapy, the system including a wearable garment having one or more inflatable chambers, and a pneumatic engine locally coupled to the garment to provide control and inflation of the one or more inflatable chambers. In an illustrative embodiment, the pneumatic engine may control a pump and one or more valves to inflate the inflatable chambers. The valves and pump may be coordinated according to a pre-programmed profile. In some embodiments, the pneumatic engine may have a wireless interface configured to receive control signals from a remote mobile device untethered from the garment. The pneumatic engine may send to the remote mobile device signals indicative of sensed conditions of the compression therapy system. In some embodiments, the pneumatic engine may include a power source that advantageously permits the user to be untethered from a source of power.

Abstract: A massage device includes a linear series of inflatable massage cells, a common supply and venting line, an air pump, a controllable valve, a control unit, and a passive flow restrictor. The cells are arranged in succession and adapted to be disposed beneath a seat cover. The cells include a primary massage cell and a secondary massage cell arranged in a longitudinal direction. The line is in communication with the primary and secondary massage cells. The pump is connected to the line. The control unit is arranged for carrying out massage functions by controlling the compressed air pump and the valve according to a predetermined sequence set by a user for the controlled inflation and controlled venting of the linear massage cells. The flow restrictor interposes the line, and is spaced between the primary massage cell and the secondary massage cell.

Abstract: Provided is a facial massage device including: a massage head (1) that includes: a bearing element (20) that forms a bearing ring (21) defining a bearing surface (S) lying within a bearing plane (P) and a working area (Z) located within the bearing ring, within the bearing ring and inside the working area (Z), at least one working head (22) that has a working surface that extends, protruding, from the bearing plane (P), maneuvering device (25) designed to move each working head (22) in rotation about at least one axis of rotation (?, ??) offset relative to the centre of the corresponding working surface (T), and a drive housing that carries the massage head (1) and that includes an electric motor (6) that actuates drive means (7) designed to transmit the drive from the electric motor (6) to the maneuvering device (25).

Abstract: A computer-implemented system/method for entertainment system by a first camera to capture an image of a sex prospect and a second camera to capture eye gazing; a processor coupled to the second camera to determine interest in the sex prospect, the processor coupled to the first camera to analyze prospect information including appearance and body shape therefrom, the processor comparing the interest and prospect information with prior likings; and a projector aimed at a retina, the projector displaying a virtuality reality or augmented view of the sex prospect.

Abstract: An electromechanical device for male sexual stimulation that uses a reciprocal linear motion similar to sexual intercourse, and wherein the penis remains fully inserted during use. The reciprocal linear motion is generated by a small motor which drives a screw and nut mechanism, to which a bracket and gripper is attached. Inserted into the gripper is a flexible sleeve. A penis may be inserted into the device inside the flexible sleeve. The movement of the gripper and sleeve against the penis provides pressure and motion against the penis inside the sleeve in a manner similar to sexual intercourse. The speed, pattern, and location of the motion can be controlled by the user through controls on the outside of the device.

Abstract: An electromechanical device for male sexual stimulation that uses a reciprocal linear motion similar to sexual intercourse, and wherein the penis remains fully inserted during use. The reciprocal linear motion is generated by a small motor which drives a screw and nut mechanism, to which a bracket and gripper is attached. Inserted into the gripper is a flexible sleeve. A penis may be inserted into the device inside the flexible sleeve. The movement of the gripper and sleeve against the penis provides pressure and motion against the penis inside the sleeve in a manner similar to sexual intercourse. The speed, pattern, and location of the motion can be controlled by the user through controls on the outside of the device.

Abstract: A percussive massage device includes an enclosure having a cylindrical bore that extends along a longitudinal axis. A motor has a rotatable shaft that rotates about a central axis perpendicular to the longitudinal axis. A crank coupled to the shaft includes a pivot, which is offset from the central axis of the shaft. A transfer bracket has a first end portion coupled to the pivot of the crank. A flexible transfer linkage has a first end coupled to a second end portion of the transfer bracket. A piston has a first end coupled to a second end of the transfer linkage. The piston is constrained to move within a cylinder along the longitudinal axis of the cylindrical bore. An applicator head has a first end coupled to a second end of the piston and has a second end exposed outside the cylindrical bore for application to a person receiving treatment.

Abstract: A massaging shoe including a shoe body portion formed of a vibration transmitting material and having an interior surface which includes a multiplicity of integrally formed raised surface elements and a vibrator operative to generate vibrations, the vibrations being transmitted via the vibration transmitting material and the integrally formed raised surface elements to a foot of a wearer of the shoe.

Abstract: A system for monitoring performance of a resuscitation activity on a patient by an acute care provider is provided. The system includes: a first wearable sensor configured to sense movement of a first portion of an acute care provider's hand; a second wearable sensor configured to sense movement of a second portion of the acute care provider's hand; and a controller. The controller is configured to: receive and process signals representative of performance of a resuscitation activity from the first sensor and the second sensor; identify from the processed signals information indicative of at least one of a relative distance, a relative orientation, a change in relative distance and a change in relative orientation between the first sensor and the second sensor during performance of the resuscitation activity; and determine at least one resuscitation activity parameter based, at least in part, on the identified information.

Abstract: A method includes performing, by a processor: providing a database that contains records corresponding to a plurality of drug product packaging systems, the records in the database being accessible through a common database management system, receiving a packaging order for at least one drug product, evaluating at least one criterion for fulfilling the packaging order, and identifying one of the plurality of drug product packaging systems to package the at least one drug product based on evaluating the at least one criterion.

Abstract: A storage device having a cylindrical housing with a first end, a second end and cylindrical side, wherein the ends are closed and the cylindrical side has one or more apertures. There is a cylindrical cover for each of the one or more apertures that slidably fit over the cylindrical side of the cylindrical housing and able to slide about the cylindrical side exposing or covering the one or more apertures.

Abstract: A device is disclosed for reconstitution and delivery of an injectable pharmaceutical. A diluent is provided in a pressurized reservoir, while separately a syringe with a needle contains a pharmaceutical such as a lyophilized drug. When the pressurized reservoir is coupled to the interior of the syringe, such as by piercing the pressurized reservoir with the needle, the pressurized reservoir forces the diluent into the syringe where the diluent can mix with and reconstitute the pharmaceutical. A variety of techniques are disclosed for pressurizing the reservoir and fluidly coupling the reservoir with the syringe. The techniques disclosed herein may, for example, be adapted for use with a conventional syringe and needle.

Abstract: A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The cassette may further have a sleeve movably disposed within the housing, for holding a drug container, and a locking arrangement for interlocking the sleeve with the housing. The cassette may further have an aperture in the housing, and a cassette cap for removing a needle shield of the drug container. The cassette may have an anti-bending structure to prevent bending or flexing of the cassette cap. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detecting and communicating the cassette ID to the microprocessor to decipher the code defined therein. Also, a method of injecting a drug into a patient with an injector, wherein the sequence of actions performed by the user are controlled.

Abstract: A medication container encoding, verification and identification method is provided that includes receiving data characterizing a medication, generating an identifier encapsulating the data and applying an identifier to a medication container such that it is automatically readable by a medication device. Related apparatus, systems, methods and articles are also described.

Abstract: An ointment squeeze ball has an exit orifice for dispensing ointment. A colorant squeeze ball has an exit orifice for dispensing colorant. A mixing tube has an input end, an exit applicator tip, and an elongated passageway with helical mixing vanes. A central component in a Y-shaped configuration with a central passageway removably couples the ointment squeeze ball and the mixing tube. The central component has a lateral leg with a lateral passageway removably coupling the colorant squeeze ball and an intermediate region of the central passageway.

Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.