Patents Issued in December 10, 2019
-
Patent number: 10500312Abstract: Bioactive porous bone graft implants in various forms suitable for use in bone tissue regeneration and/or repair, as well as methods of use are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may be contained in polymer for enhanced clinical results and better handling.Type: GrantFiled: November 17, 2014Date of Patent: December 10, 2019Assignee: PROSIDYAN, INC.Inventors: Charanpreet S. Bagga, Steve B. Jung, Hyun W. Bae
-
Patent number: 10500313Abstract: Disclosed is a method for producing a porous monolithic material from at least one powder, preferably mineral, the method including at least one step of low-temperature compression of a mixture based on powder and at least one solvent, preferably water. The materials produced by the method have improved mechanical properties compared to the prior art materials. The materials for medical application, such as hydroxyapatite, also have improved biocompatibility compared to the prior art materials. Also disclosed are materials produced by the method.Type: GrantFiled: July 15, 2016Date of Patent: December 10, 2019Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQU, UNIVERSITE DE BORDEAUXInventors: Alain Largeteau, Mythili Prakasam
-
Patent number: 10500314Abstract: Disclosed is a flexible substrate/liquid electrolyte viscous composite material and preparation method therefor. The preparation method includes: adding a particular percentage by weight of a flexible substrate to a liquid electrolyte solution having a particular concentrate; fully stirring the solution at a particular temperature to dissolve and evenly disperse the substrate, so as to obtain a viscous liquid; and then standing the viscous liquid at a particular temperature for a particular period of time to obtain the material. The material has viscosity due to which the material can actively adhere to the surface of tissue of an organ, the mechanical property matching cardiac muscle, biocompatibility and security, and is used for treating acute and chronic myocardial infarction and heart failures, inhibiting the reconstruction, thinning, and fiberization of a ventricular wall, and improving the myocardial function. In addition, the material also features conductivity, in vivo degradability, and the like.Type: GrantFiled: April 26, 2016Date of Patent: December 10, 2019Assignee: SOOCHOW UNIVERSITYInventors: Lei Yang, Ning Sun, Xiao Lin, Wei Jiang, Xinhong Wang, Yanjie Bai, Huilin Yang, Aobing Bai
-
Patent number: 10500315Abstract: A multilayer film for ostomy and bowel management applications includes a barrier layer comprising at least about 90% wt. nylon 6/69. The multilayer film provides excellent mechanical and odor barrier properties, and softness and quietness desired in ostomy and bowel management applications.Type: GrantFiled: January 6, 2016Date of Patent: December 10, 2019Assignee: Hollister IncorporatedInventors: Moh-Ching Oliver Chang, George J. Cisko
-
Patent number: 10500316Abstract: An air-permeable guard adapted to attach to a covering, the air permeable guard comprising a plurality of layers attached together to create one or more compartments. The guard further comprises at least one agent stored in the one or more compartments wherein the at least one agent may be a counteracting agent, a masking agent or a disinfectant agent. The masking agent may be coffee, oil and self encapsulated oil beadlet. The counteracting agent may be activated charcoal, sodium bicarbonate, zeolite, diatomaceous earth, silica gel and bentonite clay. The disinfectant agent may be a water based coating containing a cationic siloxane. In another embodiment of the invention the compartments may store the agents in a portion of the guard that is adapted to come in contact with the wearer's nostrils.Type: GrantFiled: June 30, 2016Date of Patent: December 10, 2019Inventors: Marie Angela Bontigao, David Emery
-
Patent number: 10500317Abstract: Orthopedic and dental implants coated with an antibacterial coating and methods of making and using, are described herein. The implant can be coated with a hydrophobic, polycationic antibacterial polymer. The polymer can be covalently or non-covalently associated with the surface; however, in particular embodiments, the polymer is non-covalently associated with the surface. As shown in the examples below, clinical observations, digital radiography, and a battery of well-accepted ex vivo analytical methods show that the presence of a hydrophobic polycationic polymer coating, such as N,N-dodecyl,methyl-PEI coating on the surface of a metal implant, was effective in eliminating the clinical signs of infection in vivo in a large animal infection model. Moreover, the coated plates supported bone healing, and in fact decreased healing times, even in the presence of significant bacterial contamination compared to a control.Type: GrantFiled: November 16, 2017Date of Patent: December 10, 2019Assignees: Massachusetts Institute of Technology, The Trustees of the University of PennsylvaniaInventors: Thomas P. Schaer, Suzanne Stewart, Alexander M. Klibanov
-
Patent number: 10500318Abstract: Described herein are methods for the treatment of hypoxia-associated tissue damage in subjects. More particularly, the methods relate to treating hypoxia-associated tissue damage in a subject during a surgical procedure with a therapeutically effective amount of a glutamine source comprising glutamine, a dipeptide comprising glutamine, or a glutamine amino ester conjugate according to particular dosing regimens. Specifically, the methods concern a dosing scheme comprising dosing a subject during a surgical procedure with a glutamine source wherein the first dose is administered to the subject within about 30 minutes following an initial surgical incision made during the surgical procedure, one or more additional doses of the glutamine source is administered at fixed intervals of time after the first dose, and one or more doses is administered just prior to closure of all surgical incisions.Type: GrantFiled: July 3, 2018Date of Patent: December 10, 2019Assignee: Temple Therapeutics BVInventor: Lynne M. Robertson
-
Patent number: 10500319Abstract: A surgical hand piece has a source of ultrasonic energy provided to a connecting body having a first passage with one end to receive fluid from a first source and the other end at the connecting body distal end. A work tip has first and second tubes each having at least one opening at its distal end and the proximal end of one or both of the tubes connected to the connecting body distal end to receive the ultrasonic energy and to selectively receive or discharge fluid from either the first or second source as controlled by a valve. A cannula is provided which is adapted to be placed in an opening in the cornea through which the work tip extends during the removal of cataracts from the eye by phacoemulsification. The cannula may be equipped with channels that permit additional infusion of fluid into the eye during the procedure, which infusion also cools the surrounding corneal tissue to protect against heat generated by the ultrasonic vibration of the work tip.Type: GrantFiled: August 7, 2018Date of Patent: December 10, 2019Assignee: SURGICAL DESIGN CORPORATIONInventor: William Banko
-
Patent number: 10500320Abstract: Systems and methods for pumping milk from a breast, wherein the milk is expressed from the breast under suction and milk is expulsed from the pumping mechanism to a collection container under positive pressure.Type: GrantFiled: June 13, 2016Date of Patent: December 10, 2019Assignee: ExploraMed NC7, Inc.Inventors: Joshua Makower, John Y Chang, Brendan M Donohoe, Sharon Lam Wang, Michele Torosis, Earl Bright, II
-
Patent number: 10500321Abstract: A method for assisting blood circulation in a patient includes drawing a flow of blood from a patient's heart into a blood flow channel formed by a housing. The flow of blood is passed through a motor stator to a rotor disposed within the blood flow channel. The motor stator is arranged circumferentially around the blood flow channel. The rotor has permanent magnetic poles for magnetic levitation and rotation of the rotor. The motor stator is controlled to act as a radial bearing for magnetic levitation of the rotor and to rotate the rotor within the blood flow channel. The rotor is levitated within the blood flow channel in the direction of the rotor axis of rotation via passive magnetic interaction between the rotor and the motor stator. The flow of blood is output from the blood flow channel to the patient.Type: GrantFiled: May 12, 2017Date of Patent: December 10, 2019Assignee: TC1 LLCInventor: Kevin Bourque
-
Patent number: 10500322Abstract: Methods and systems are provided for determining an outlet pressure prevailing at an outlet of a heart assist system. An inlet pressure which prevails at an inlet of the heart assist system may be determined. A pressure difference between the inlet and the outlet of the heart assist system may be determined. The outlet pressure may be determined from the inlet pressure and the pressure difference.Type: GrantFiled: July 1, 2015Date of Patent: December 10, 2019Assignee: BERLIN HEART GMBHInventor: Dominik Karch
-
Patent number: 10500323Abstract: Fluid pressure or flow in a human body may be adjusted with circulation or perfusion systems and methods. The system may include a first pump implantable in a chamber or vessel of the human body, and a plurality of struts connected to a housing of the first pump, wherein the struts secure the first pump in a desired location of the chamber or vessel. The system may also include one or more flow modification elements disposed on the first pump, where the flow modification elements direct flow to a desired organ or a desired vessel to adjust pressure or flow as desired.Type: GrantFiled: January 3, 2017Date of Patent: December 10, 2019Assignee: PROCYRION, INC.Inventors: Jason J. Heuring, William L. Clifton, Benjamin A. Hertzog, Michael P. Cuchiara, Reynolds M. Delgado, III
-
Patent number: 10500324Abstract: Systems and devices for an adaptable blood pump are disclosed herein. The blood pump can be part of a mechanical circulatory support system that can include a system controller and the blood pump. The blood pump can include a rotary motor and a control unit that can communicate with the system controller. The blood pump can determine when communication with the system controller is established or has been lost. The blood pump can retrieve one or several back-up parameters when communication with the system controller has been lost, and can operate according to these back-up parameters.Type: GrantFiled: July 17, 2017Date of Patent: December 10, 2019Assignee: TC1 LLCInventors: Christian Schade, Andre Siebenhaar
-
Patent number: 10500325Abstract: A wearable filtrating artificial kidney device, comprising a transfusion inlet (2), a blood pump (3), an arterial pressure detector (4), a blood filter (7), a venous pressure detector (8) and an air detector (9), wherein the transfusion inlet (2), the blood pump (3), the arterial pressure detector (4), a resin hemoperfusion apparatus (5), an active carbon hemoperfusion apparatus (6), the blood filter (7), the venous pressure detector (8) and the air detector (9) are connected sequentially; a liquid waste outlet of the blood filter (7) is connected with an ultrafiltration control pump (10). Glomerulus filtration can be simulated to achieve the goal of removing toxins and excessive moisture in the blood by virtue of ultrafiltration of the blood filter (7). A dialyzate and a complicated dialyzate circulating device are not used for the device, so that the volume and weight of the device can be reduced greatly, and the device can be worn conveniently.Type: GrantFiled: September 23, 2016Date of Patent: December 10, 2019Inventors: Changsheng Zhao, Baihai Su, Weifeng Zhao, Shudong Sun, Chen Wang, Zhenqiang Shi, Qiang Liu, Xiaohua Zhang, Ping Fu, Jianhui Zhou
-
Patent number: 10500326Abstract: A system and apparatus for opening and emptying a bag of material includes a base having a pair of opposed sides and a central aperture through which material may flow. The system includes a pair of opposed doors rotatably mounted on a pair of door shafts, the edges of the pair of opposed doors forming an opening and a plurality of piercing blades pivotally mounted to the base on a pivot rod, the blades capable of pivoting to pierce said bag. The system further includes a cutting blade mounted transversely below the opening of the opposed doors, the cutting blade capable of linear motion across the opening.Type: GrantFiled: June 20, 2018Date of Patent: December 10, 2019Assignee: ISOPURE, CORP.Inventors: Kevin C. Gillespie, Zachary Patrick Ford, Guillermo J. Cohen Freue
-
Patent number: 10500327Abstract: A blood circuit assembly for a dialysis unit may include an organizing tray, a pair of pneumatic pumps mounted to the organizing tray for circulating blood received from a patient through a circuit including a dialyzer unit and returned to the patient, an air trap mounted to the organizing tray arranged to remove air from blood circulating in the circuit, a pair of dialyzer connections arranged to connect to the inlet and outlet of a dialyzer unit, and a pair of blood line connectors, one inlet blood line connector for receiving blood from the patient and providing blood to the pneumatic pumps and the other outlet blood line connector for returning blood to the patient.Type: GrantFiled: June 1, 2018Date of Patent: December 10, 2019Assignee: DEKA Products Limited PartnershipInventors: Kevin L. Grant, James D. Dale, Michael J. Wilt, Jason A. Demers, David E. Collins, Brian D. Tracey
-
Patent number: 10500328Abstract: A whole blood hollow fiber membrane filter medium is provided with a ceramic material having pores of a pore size that ensures permeability to blood plasma or serum and its molecular components while blood cells are retained. The whole blood hollow fiber membrane filter medium is used for separating blood plasma from whole blood, wherein the blood plasma preferably shows no hemolysis.Type: GrantFiled: December 14, 2015Date of Patent: December 10, 2019Assignee: MANN+HUMMEL GmbHInventors: Steffen Schuetz, Heike Rupp, Tobias Woerz, Dagmar Winkler, Kathrin Woerz, Frank Ehlen, Karlheinz Muenkel, Joachim Stinzendoerfer
-
Patent number: 10500329Abstract: A valve for controlling material flow through a catheter, comprises a first flexible member including a first moveable element, wherein, when the first moveable element is in the open position, material may flow past the first flexible member through a first lumen of the catheter and, when the first moveable element is in the closed position, flow through the first lumen is prevented and a first biasing member coupled to the first flexible member for biasing the first moveable member toward the closed position.Type: GrantFiled: September 18, 2015Date of Patent: December 10, 2019Assignee: AngioDynamics, Inc.Inventors: Karla Weaver, Jim Cuthane
-
Patent number: 10500330Abstract: A method for collecting and washing shed blood includes providing a blood salvage reservoir and a blood salvage system. The user may connect a vacuum inlet port on the reservoir to a vacuum outlet port on the salvage system, connect an inlet port on the reservoir to a patient, and connect a vacuum source to a vacuum connection port on the salvage system. The method may then (1) draw a vacuum on the reservoir to draw shed blood into the reservoir, (2) disconnect the reservoir from the surgical field and salvage system, and (3) connect a second reservoir. The first blood salvage reservoir may then be connected to an automated blood processing system, and the collected blood may be introducing into the automated blood processing system and washed. The blood processing system may then return a portion of the washed blood to the patient.Type: GrantFiled: October 7, 2015Date of Patent: December 10, 2019Assignee: Haemonetics CorporationInventors: Donald J. Schwarz, Seth Kasper, Lisa Fahey
-
Patent number: 10500331Abstract: A drainage catheter with retractable internal drains for fluid drainage and irrigation includes a primary catheter for insertion within a subject, a lumen within the primary catheter for conducting fluid flow between a source of fluid drainage or irrigation and the subject, and a plurality of selectively retractable and deployable drains in fluid communication with the lumen. Retraction and deployment of the drains within a subject is accomplished remotely via a specially shaped stylet and common drain connector within the primary catheter. The plurality of drains are enclosed within the primary catheter in the retracted state and extend radially outwardly from the primary catheter in the deployed state. In the retracted state, insertion and location of the primary catheter in a subject are facilitated. In the deployed state, expanded and improved drainage and irrigation area and a plurality of fluid flow paths and locations are provided.Type: GrantFiled: August 18, 2017Date of Patent: December 10, 2019Inventor: Ayman H. Al-Jazaeri
-
Patent number: 10500332Abstract: Systems and methods are provided for injecting one or more agents into tissue within a patient's body. In one embodiment, an injection device includes a substantially axially incompressible elongate member including a lumen extending between proximal and distal ends thereof. A distal stop is provided on the distal end and a needle tip extends distally beyond the distal stop, the needle tip having a cross-section smaller than the distal end. The needle tip includes a passage communicating between the lumen and an outlet in the distal tip that has having a cross-section smaller than the lumen. In an exemplary embodiment, the elongate member includes a coil extending between the proximal and distal ends, and a sleeve disposed within an interior region of the coil extending between the proximal and distal ends. The sleeve defines the lumen and may be free-floating within at least a portion of the coil.Type: GrantFiled: October 3, 2016Date of Patent: December 10, 2019Assignee: CLPH, LLCInventors: Stephen A. Leeflang, Christian S. Eversull
-
Patent number: 10500333Abstract: Disclosed is a system and a method for determining an injectable amount of bile required for a patient after gallbladder removal. The system comprises a receiving module, a creating module, and a determining module. The receiving module may receive a bile-flow rate, physiological parameters of a patient, and amount of fatty food in an alimentary tract of the patient. Based on these data received, the creating module may create a graph. Further, the determining module may determine a correlation between the bile-flow rate and the amount of fatty food in the alimentary tract based on the graph created. The correlation may be determined corresponding to a normal person and the patient which may be seen by two separate curves on the graph. Further, the determining module may determine an injectable amount of bile required for the patient based on the correlation.Type: GrantFiled: December 18, 2015Date of Patent: December 10, 2019Assignee: HCL Technologies LimitedInventors: Shyam Thangaraju, Siva Sakthivel Sadasivam, Vishal Chaudhary
-
Patent number: 10500334Abstract: The embodiments described herein may relate to methods and systems for adjusting insulin delivery. Some methods and systems may be configured to adjust insulin delivery to personalize automated insulin delivery for a person with diabetes. Some methods and systems may be configured to adjust insulin delivery to a person with diabetes according to one or more conditions of an insulin delivery device. Some methods and systems may be configured to enable a lock-out mode where adjustment to insulin delivery to personalize automated insulin delivery is restricted.Type: GrantFiled: January 12, 2018Date of Patent: December 10, 2019Assignee: Bigfoot Biomedical, Inc.Inventors: Bryan Mazlish, Lane Desborough, Ross Naylor
-
Patent number: 10500335Abstract: A sub-assembly for a medicament delivery device including a housing, a propellant source contained in and axially moveable relative to said housing, and a button axially moveable relative to said housing. At least part of said button is disposed axially rearwardly of part of said propellant source. The button includes one or more radially flexible blocking members, and the button is moveable between a first axial position in which the one or more radially flexible blocking members are radially restrained by the housing in a radially inward position that limits rearward axial movement of the propellant source, and a second axial position in which the one or more radially flexible blocking members are able to flex to a radially outward position and permit rearward axial movement of the propellant source relative to the button and the housing.Type: GrantFiled: November 3, 2014Date of Patent: December 10, 2019Assignee: CONSORT MEDICAL PLCInventors: Rachel Koppelman, Alan Judd, Alastair Willoughby
-
Patent number: 10500336Abstract: The present disclosure relates to the smart wear field. The smart wearable device comprises: a main body comprising a control unit and a biological feature parameter acquisition module, the biological feature parameter acquisition module is configured to acquire a monitored biological feature parameter of a user, and the control unit is configured to compare the monitored biological feature parameter and a pre-stored biological feature reference parameter so as to determine whether the user is in need of first aid according to the comparative result; a connecting part for putting on the smart wearable device on the body of the user; a power supply module for supplying power to the smart wearable device; and a first-aid processing module configured to give first aid to the user when it is determined according to the comparative result that the user is in need of first aid.Type: GrantFiled: September 5, 2016Date of Patent: December 10, 2019Assignees: BOE TECHNOLOGY GROUP CO., LTD., HEFEI BOE OPTOELECTRONICS TECHNOLOGY CO., LTD.Inventors: Fei Xu, Jun Hong
-
Patent number: 10500337Abstract: An autoinjector having a body (1) receiving a reservoir (S) containing fluid and including a piston (P), such as a pre-filled syringe; a piston rod (5) that co-operates with the piston (P), the piston rod (5) being movable by an injection spring (8) between a primed position and an injection position in which the piston rod (5) has moved the piston (P) of the reservoir (S) so as to inject the fluid into an injection site; and an indicator device for indicating to the user that the autoinjector may be removed from said injection site. The autoinjector also includes a retarding system to delay the end of actuating the indicator device relative to the end of injection, the indicator device generating a noise while being actuated, the noise being generated until the end of actuating the indicator device.Type: GrantFiled: June 2, 2016Date of Patent: December 10, 2019Assignee: APTAR FRANCE SASInventors: David Fabien, Thomas Gomez, Anthony Saussaye, Philippe Pinheiro
-
Patent number: 10500338Abstract: A drug delivery device comprising a drug container extending between a distal end and a proximal end and is capable of being compressed into a single plane; a body extending between proximal and distal ends comprising a hollow space for containing the drug container; and a plunger extending between proximal and distal ends, wherein the distal end of the plunger engages telescopically with the proximal end of the body, wherein the plunger comprises at least one pair of protrusions, wherein the protrusion is capable of compressing the drug container as the plunger moves towards the proximal end of the drug delivery device, by applying a force to the drug container that is perpendicular to the movement of the plunger.Type: GrantFiled: April 12, 2016Date of Patent: December 10, 2019Assignee: Merck Sharp & Dohme Corp.Inventor: Annaniy Berenshteyn
-
Patent number: 10500339Abstract: The present invention relates to an impregnation process for a fibrous substrate, a liquid composition for implementing this process and the obtained impregnated fibrous substrate. The impregnated fibrous substrate is suitable for manufacturing mechanical or structured parts or articles. In particular the present invention deals with an industrial process for impregnating a fibrous substrate or long fibers with a viscous liquid composition containing mainly methacrylic, vinylic or acrylic components either in form of monomers or polymers. This viscous composition is called hereafter liquid monomer syrup. The invention concerns also a fibrous substrate pre-impregnated with said syrup which is useful for manufacturing mechanical or structured parts or articles. More particular the impregnation of fibrous substrate with the monomer syrup is achieved in a mould.Type: GrantFiled: January 22, 2015Date of Patent: December 10, 2019Assignee: Arkema FranceInventors: Pierre Gerard, Michel Glotin, Sebastien Taillemite
-
Patent number: 10500340Abstract: A smart injection system that promotes patient safety includes, among other things, a smart stem that allows for measuring the location of the injection relative to the patient's face and/or the amount of medication injected into the patient. In addition, the smart stem has medication cartridge verification and injector verification features. The smart stem wirelessly transmits the measure data to a processing system.Type: GrantFiled: October 20, 2016Date of Patent: December 10, 2019Assignee: Truinject Corp.Inventors: Gabrielle A. Rios, Clark B. Foster
-
Patent number: 10500341Abstract: An assembly for an auto injector device, the assembly including a syringe support for supporting a syringe by limiting forward axial movement of the syringe relative to the syringe support, and a guard element attachable to the syringe support by an attachment so that the guard element is axially restrained both axially forwardly and axially rearwardly relative to the syringe support by the attachment. Forwardly directed axial loads received by the guard element are transmitted to the syringe support via the attachment.Type: GrantFiled: August 4, 2014Date of Patent: December 10, 2019Assignees: Bespak Europe Limited, UCB Biopharma SPRLInventors: Martin John McLoughlin, Ian Darnell, Matt Ekman, Ian Anderson, Neil Bentley Cammish
-
Patent number: 10500342Abstract: A cold slurry syringe with enhanced features is provided for delivering a cold slurry into the human body. The syringe includes a syringe body for holding a volume of cold slurry, a plunger that slides within the syringe body for ejecting the cold slurry, and a tapered syringe head for delivering an even flow of cold slurry. An agitator can be added to keep the cold slurry from agglomerating and clogging the syringe. Insulation added around the syringe can keep the cold slurry from melting too quickly. A ball screw drive can be added to provide a smooth and consistent application of pressure as the cold slurry is delivered. The cold slurry flow can be enhanced by adding a streamline flow feature that reduces the occurrence of eddies or swirls inside the syringe. This feature can also help maintain the composition and consistency of the cold slurry.Type: GrantFiled: August 21, 2017Date of Patent: December 10, 2019Assignee: MIRAKI INNOVATION THINK TANK LLCInventor: Christopher J. P. Velis
-
Patent number: 10500343Abstract: This invention relates to a method of identifying an accurate dosage of medicine in a dosage chamber of a syringe including the steps of providing an accurate dosage of a detailed single dosage medicine for insertion into a dosage chamber of a syringe; identifying the accurate dosage of medicine in the dosage chamber by retaining a notifier of the accurate dosage; securing the notifier with the syringe wherein the accurate dosage of medicine in a dosage chamber of a syringe is shown by the details on the notifier when secured with the syringe and allowing usage of the syringe to dispense the accurate dosage.Type: GrantFiled: November 21, 2014Date of Patent: December 10, 2019Assignee: JAY-NIK PTY LTD (ACN 620 076 253)Inventor: George Poulos
-
Patent number: 10500344Abstract: Injection systems with storage compartments to house various materials are described. The storage compartments facilitate provision of medical care in space- and time-efficient manners and are particularly useful in providing care in non-medical facilities.Type: GrantFiled: March 24, 2016Date of Patent: December 10, 2019Assignee: Hyprotek, Inc.Inventor: Patrick O. Tennican
-
Patent number: 10500345Abstract: A spring assisted drug delivery device is provided comprising a housing and a lead screw having a longitudinal axis, a distal end and a proximal end that is rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing. The device further comprises a drive nut threadedly engaged and screwable along the lead screw threaded shaft and a number sleeve threadedly engaged with the housing to be screwable relative to the housing. A dial link is connected with the drive nut and axially movable and rotatably fixed relative to the drive nut and an inner sleeve is threadedly engaged with the number sleeve, the inner sleeve being axially movable and rotatably fixed relative to the housing. A mid-body is axially fixed inside of the housing. A spring is provided that assists a user of the device during a dose administration step.Type: GrantFiled: November 17, 2014Date of Patent: December 10, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Stefan Blancke, Axel Teucher, Michael Jugl, Christiane Schneider
-
Patent number: 10500346Abstract: An assembly for a drug delivery device includes a dose setting member to be moved by a user from an initial position to a dose sett position and a housing part. The dose setting member and the housing part are connected to form a housing of the assembly. The assembly includes an activation member coupled to the dose setting member to convert a rotation of the dose setting member with respect to the housing into a proximal movement of the activation member with respect to the dose setting member when the dose setting member is moved from the initial position to the dose set position. The activation member has a proximal end section extending from an activation face of the activation member, where in the initial position of the dose setting member, the proximal end section is fully in or slightly protrudes from the proximal end of the housing.Type: GrantFiled: September 3, 2014Date of Patent: December 10, 2019Assignee: SanofiInventors: Michael Bainton, David Aubrey Plumptre
-
Patent number: 10500347Abstract: Described is a cap (60) for covering a needle shield (29) on a needle (26) of a medicament container (20), the cap (60) comprising a cylindrical portion (61) having a first outer diameter, a disc portion (62) disposed on a distal end of the cylindical portion (61), the disc portion (62) having a second outer diameter larger than the first outer diameter; and a gripping surface (63) disposed on an inner surface of the cylindiral portion (61) and adapted to frictionally engage a needle shield (29) on a needle (26).Type: GrantFiled: August 27, 2014Date of Patent: December 10, 2019Assignee: SanofiInventors: David Darras, Fabien Canepa, Bruno Serre, Jacky Mazzolini
-
Patent number: 10500348Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.Type: GrantFiled: December 4, 2015Date of Patent: December 10, 2019Assignee: Janssen Biotech, Inc.Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
-
Patent number: 10500349Abstract: This invention is an air block for industrial, medical, and non-medical uses. For example, the air block is connected to the proximal end of a vascular access catheter. The air block is either removably connected to the proximal end of the catheter or it is integral to the proximal end of the catheter. The air block permits introduction of other catheters or instrumentation through its central lumen and on into a lumen of the catheter while minimizing fluid loss or gain into the catheter. The air block further prevents air from entering the catheter and provides for removal of the air or other gas from the central lumen before it can enter the catheter where it could cause harm to the patient. The air block can be attached to various standard proximal catheter terminations including Luer fittings and hemostasis valve outer barrels.Type: GrantFiled: September 19, 2017Date of Patent: December 10, 2019Assignee: The Regents of the University of CaliforniaInventors: Kalyanam Shivkumar, David A. Cesario
-
Patent number: 10500350Abstract: It is known in the art to use an apparatus to enhance the visual appearance of the veins and arteries in a patient to facilitate insertion of needles into those veins and arteries. This application discloses a number of inventions that add additional data collection and presentation capabilities to a handheld vein enhancement apparatus and a set of processes for the collection of blood and the delivery of IV medicines that use the handheld device to mediate the process.Type: GrantFiled: April 12, 2016Date of Patent: December 10, 2019Assignee: AccuVein, Inc.Inventors: Fred Wood, Ron Goldman, Stephen P. Conlon, Vincent Luciano
-
Patent number: 10500351Abstract: The present disclosure is concerned with a device for facilitating a subcutaneous injection and a process for administering the subcutaneous injection. The device has a peripheral frame and an injection needle or an aperture in a central portion of the frame adapted to hold an injection needle. The peripheral frame has an arm or arms adapted to contact the skin at points distant enough from each other to allow the arms or arm to penetrate into the skin a distance greater than the thickness of the skin, a central portion which joins the arms above the terminal portions or portion and an injection needle affixed to the central portion, facing in the same direction as the penetration ends of the arms or an aperture in the central portion adapted to hold an injection needle facing in the same direction as the penetration ends of the arms.Type: GrantFiled: September 11, 2016Date of Patent: December 10, 2019Inventor: Shawn Michael Michels
-
Patent number: 10500352Abstract: An infusion pump assembly includes a locking tab and a pump barrel inside a pump barrel housing, where the pump barrel accommodates a reservoir assembly. The reservoir assembly includes a reservoir and a plunger rod. The infusion pump assembly also includes a locking disc at a terminus of the pump barrel. The locking disc includes a clearance hole for the plunger rod. The locking disc also includes at least one locking tab notch in close proximity with the locking tab. The locking tab is in moveable engagement with the locking tab notch, and the reservoir moves the locking tab from a locked position to an unlocked position when the plunger rod is inserted through clearance hole. The locking disc rotates upon torque being applied to the reservoir assembly, the locking disc rotating from a non-loaded position to a loaded position with respect to the plunger rod and a drive screw.Type: GrantFiled: September 19, 2016Date of Patent: December 10, 2019Assignee: DEKA PRODUCTS LIMITED PARTNERSHIPInventors: Kevin L. Grant, Brian L. Tracey, Marc Aurele Mandro, Robert John Bryant, Jr.
-
Patent number: 10500353Abstract: The present disclosure relates to a medicament delivery device for injection of a medicament. The medicament delivery device comprises a housing (3) arranged to receive a medicament delivery member, a medicament delivery member cover (7) received by the housing (3), which medicament delivery member cover (7) has a cap-fitting portion (7a), wherein the medicament delivery member cover (1) is moveable relative to the housing (3) from an extended position in which the cap-fitting portion (7a) extends from the housing (3), to a retracted position in which the medicament delivery member cover (7) is biased towards the extended position, and a cap (11) arranged to receive the cap-fitting portion (7a), wherein the medicament delivery member cover (7) and the cap (1) comprise a tamper evidence mechanism which is activated by removal of the cap (11) from the cap-fitting portion (7a).Type: GrantFiled: September 30, 2015Date of Patent: December 10, 2019Assignee: SHL Medical, AGInventor: Daniel Sall
-
Patent number: 10500354Abstract: An atomizer includes a cartridge with a reservoir containing a fluid and a heating system configured to atomize the fluid into a vapor for inhalation. A respiratory indicator is configured to determine an inhalation period and an exhalation period of a patient using the atomizer. The atomizer then increases atomization of the vapor during the inhalation period and decreases atomization of the vapor during the exhalation period. An impedance sensor measures an amount of the fluid in the atomizer and deactivates atomization in response to an indication of a low fluid level.Type: GrantFiled: March 17, 2017Date of Patent: December 10, 2019Assignee: SANMINA CORPORATIONInventor: Robert Steven Newberry
-
Patent number: 10500355Abstract: The invention relates to a system composed of an inhaler and a capsule, preferably intended for single use. The capsule contains a preferably powdered pharmaceutical preparation which, for inhalation, is expelled from the capsule through at least one hole. The capsule comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. The prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pulling mechanism. Prior to this the hole is closed off by a capsule receptacle or a film. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed. Also shown is an inhaler suitable as a disposable product, which is manufactured from thermoformed parts or from blister film.Type: GrantFiled: May 17, 2013Date of Patent: December 10, 2019Assignee: Boehringer Ingelheim International GmbHInventors: Holger Holakovsky, Jessica Frentzel-Beyme, Stephen Terence Dunne, Jens Besseler, Claudius Weiler
-
Patent number: 10500356Abstract: The present disclosure pertains to a system and method for controlling insufflation pressure during inexsufflation of a subject. The system inexsufflates the subject such that tidal flow and/or tidal volume are monitored during insufflation, and insufflation pressure is adjusted to maintain the flow rate of the pressurized flow of breathable gas until a target tidal volume is reached for the insufflation. When the target tidal volume has substantially been reached, the system is causes gas to be evacuated from the airway of the subject. This may provide for more precise, customized therapy for the subject than is provided by conventional inexsufflation systems in which inspiratory flow may not be monitored and/or controlled. In one embodiment, the system comprises one or more of a pressure generator, a subject interface, one or more sensors, a processor, a user interface, electronic storage, and/or other components.Type: GrantFiled: March 19, 2013Date of Patent: December 10, 2019Assignee: Koninklijke Philips N.V.Inventors: Peter Douglas Hill, Seunghyun Lee, April Stewart Nathan
-
Patent number: 10500357Abstract: Methods and systems to treat Cheyne-Stokes respiration (CSR) and/or central sleep apnea (CSA) include monitoring retrograde breathing and detecting respiratory events. Based on the occurrences of certain respiratory events, a target volume of rebreathing is adjusted to reduce arousals as well as CSR/CSA.Type: GrantFiled: March 20, 2012Date of Patent: December 10, 2019Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Manuel Laura Lapoint, Leonardo Alberto Baloa Welzien
-
Patent number: 10500358Abstract: A gas regulator is described. The gas regulator includes a gas inlet having an attachment mechanism for attaching to a gas container, a gas outlet in fluid communication with the gas inlet and further in fluid communication with a gas delivery system, a pressure regulator, a pressure sensor and a NFC sensor. A method of entering at least one information item relating to a gas source to a gas delivery system control unit. The method includes the steps of providing a gas source having a NFC tag that includes at least one information item stored in a memory of the NFC tag, attaching a regulator that includes a NFC sensor, wherein the NFC sensor is positioned to read the NFC tag when attached to the gas source, reading the at least one information item via the NFC sensor, and transmitting the at least one information item read by the NFC sensor to a gas delivery system control unit.Type: GrantFiled: November 8, 2013Date of Patent: December 10, 2019Assignee: 12th Man Technologies, Inc.Inventors: Alex Stenzler, Steve Han
-
Patent number: 10500359Abstract: The invention relates to a method and a device for treating Cheyne-Stokes respiration, periodic respiration and central or mixed apnea. If the respiration waxes and wanes periodically, there is pressure support in phases of periodic respiration, taking into account the natural patient respiration.Type: GrantFiled: March 26, 2015Date of Patent: December 10, 2019Assignee: LOEWENSTEIN MEDICAL TECHNOLOGY S.A.Inventors: Matthias Schwaibold, Christof Schroeter
-
Patent number: 10500360Abstract: In embodiments of the present invention, a suction cleaning system component is provided for use in cleaning an interior of a tracheal ventilation tube when the suction cleaning system component is connected to the tracheal ventilation tube and a ventilator. Typically, the suction cleaning system component is used in a closed endotracheal suction system environment. The suction cleaning system component comprises a cleaning catheter and a manifold. The manifold comprises an obstruction element, which is moveable with respect to (i) the ventilator port and (ii) the expandable element. The obstruction element is configured to assume a plurality of states, including an obstruction state.Type: GrantFiled: August 10, 2015Date of Patent: December 10, 2019Assignee: TELEFLEX LIFE SCIENCES UNLIMITED COMPANYInventor: Oron Zachar
-
Patent number: 10500361Abstract: A retention system for use with a bridle installed in a nose of a patient includes a member coupled to a medical device that is suspended from a nose of a patient and a connector for coupling to a bridle that is installed in a nose of a patient. The medical device extends into the mouth of a patient or is suspended adjacent the face of a patient.Type: GrantFiled: September 2, 2016Date of Patent: December 10, 2019Assignee: APPLIED MEDICAL TECHNOLOGY, INC.Inventors: Grant W. Phillips, Kathleen Walsh, Elizabeth A Meyer, Derek M. Williams, George J. Picha