Abstract: An apparatus include an elastomeric barrier that circumscribes a PPG sensor on an underside of a housing of a wearable device. The elastomeric barrier is configured to maintain a position of the housing on the human's skin to fix the PPG sensor at a location on the human's skin to sense the function of a human organ at the location on the human's skin. The apparatus can include an enclosure that attaches to and at least partially encloses the housing of the wearable device. The apparatus can further include a band with tightly spaced ridges, and a ratchet configured to apply micro-sized adjustments for applying tension by the band to secure the wearable device to the location on the human's skin.

Abstract: A photoelectric pulse sensor includes a light emitting device and a light receiving device disposed on a main surface of a circuit board with a predetermined distance apart from each other. A housing is provided to which the circuit board is attached and including a pair of openings respectively corresponding to the light emitting and receiving devices, with the housing including a light shield disposed at least between the pair of openings. The light shield includes a light shield member that is disposed on a surface of the housing facing the circuit board. The light shield member has a light shielding characteristics and flexibility. The light shield member is deformed by coming into contact with the circuit board when the circuit board is attached to the housing.

Abstract: An apparatus and a method of measuring bioinformation are provided. The apparatus for measuring bioinformation includes a first sensor configured to measure a first biosignal including arterial pulse wave information, a second sensor configured to measure a second biosignal including venous or capillary pulse wave information, and a bioinformation estimator configured to estimate bioinformation of a user based on a time delay between the first biosignal and the second biosignal.

Abstract: Electrocardiographic waveforms for a plurality of candidate segments (analysis unit segments) are extracted from collected electrocardiographic waveforms and the extracted electrocardiographic waveforms for the plurality of candidate segments (analysis unit segments) are displayed on one screen. As a result, a user can determine, e.g., what candidate segment (analysis unit segment) analysis results to view while simultaneously viewing the electrocardiographic waveforms for the plurality of candidate segments (analysis unit segments) and which candidate segment to record, without any switching between screens, and as a result can perform appropriate electrocardiogram analysis using a simple operation.

Abstract: A leadless wireless ECG measurement system for measuring of bio-potentials includes at least one multi-contact bio-potential electrode assembly adapted for attachment to the patient's body to measure ECG. A processing unit is configured to produce a transfer function which computes estimated long-lead ECG signals based on the measured short-lead ECG signals from the plurality of contact points. This invention describes calibration process of short-lead ECG with standard lead ECG without requiring use of lead wires, only using a flexibly moving body part (finger) to calibrate patch. The invention describes use of algorithms for biopotential signal separation from mixed sources. The invention describes use of signal separation for identification of abnormal signals and the localization of biopotential source tissue. This invention describes effective biopotential evoked potential stimulation. The invention also describes biopotential neutralization of undesired biopotential.

Abstract: The invention provides an assembly comprising: a recording assembly for recording a time-based brain-related signal; a stimulus generator for providing a stimulus, and a computer assembly, functionally coupled to said recording assembly and to said stimulus generator, said computer assembly comprising: a memory for storing at least a data segment of said time-based brain-related signal during recording of said time-based brain-related signal, and a computer program which, when running on said computer assembly, functionally real-time performs: retrieving a most-recent data segment of said stored data segment of said time-based brain-related signal; fitting at least one curve to said retrieved most-recent data segment; predicting a future continuation of said most-recent data segment using said at least one curve fitted to said most-recent data segment; detecting a predefined pattern in said predicted future continuation for predicting occurrence of said predefined pattern, and defining a predicted event time

Abstract: When a user uses a finger to press and hold a first candidate display area, the first candidate display area is enclosed in a selection frame (W1), a simple window (W10) is displayed, and analysis results relating to a first candidate segment waveform are displayed in this simple window (W10). Analysis results can therefore be confirmed without switching screens and, as a result, inspection results can be confirmed with fewer steps and an electrocardiographic waveform and analysis results therefor can be compared on the same screen.

Abstract: A physiological data acquisition system includes at least one interface module and a base unit configured to communicatively connect to the at least one interface module to receive the physiological signals recorded by a catheter. Each interface module is formed by mating at least a first one of the two or more different personality modules to a dock. The dock has a multi-modal connection port configured to directly connect to a dock connector of any one of the two or more different personality modules so as to receive physiological signals therefrom. The first personality module includes a first catheter connector configured to receive a connection end of the catheter so as to receive physiological signals therefrom, and a first dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto.

Abstract: Various embodiments of the present disclosure can include a flexible catheter tip. The flexible catheter tip can comprise an inboard understructure that defines a tip longitudinal axis, wherein the inboard understructure is formed from a first continuous element that includes a first rectangular cross-section. In some embodiments, an outboard understructure can extend along the tip longitudinal axis, wherein the outboard understructure is formed from a second continuous element that includes a second rectangular cross-section.

Abstract: Traditionally arousal classification has been broadly done in multiple classes but have been insufficient to provide information about how arousal level of user changes over time. Present disclosure propose a continuous and unsupervised approach of monitoring the arousal trend of individual from his/her heart rate by obtaining instantaneous HR for time windows from a resampled time series of RR intervals obtained from ECG signal. A measured average heart rate (a measured HR) is computed from instantaneous HR specific to user for each time window thereby estimating apriori state based on a last instance of an aposteriori state initialized and observation of a state space model of Kalman Filter is determined for computing error and normalizing thereof which gets compared with a threshold for continuous monitoring of arousal trend of the user. The aposterior state is further updated using Kalman gain computed based on measurement noise determined for state space model.

Abstract: In a method and apparatus for acquiring magnetic resonance data of an acquisition region of a patient, in particular at least a part of the head of the patient, navigator data are acquired for motion correction, between diagnostic data acquisition time windows, in navigator time windows by execution of a fat navigator sequence. The fat navigator sequence has a fat-selective excitation module with at least one radio-frequency pulse and a readout module undersampling in a respective navigator slice. Motion data for the motion correction of the diagnostic data are determined from the navigator data. The navigator data are acquired simultaneously from multiple excited fat navigator slices in the fat navigator sequence using simultaneous multislice imaging, after the excitation module acts on a number of fat navigator slices to be acquired in the readout module.

Abstract: In accordance with some embodiments, systems, methods, and media for automatically diagnosing IPMNs using multi-modal MRI data are provided. In some embodiments, a system comprises: an MRI scanner; and a processor programmed to: prompt a user to select a slice of T1 and T2 MRI data including the subject's pancreas; generate minimum and maximum intensity projections based consecutive slices of the T1 and T2 MRI data; provide the projections to an image recognition CNN, and receive feature vectors for each from a fully connected layer; perform a canonical correlation analysis to determine correlations between the feature vectors; and provide a resultant vector to an SVM that determines whether the subject's pancreas includes IPMNs based on a vector.

Abstract: Methods, systems, apparatuses, and/or devices for determining a physiological condition for an individual. The methods, systems, apparatuses, and/or devices may include a housing, a sensor interface, a processing device, and a display device. The sensor interface may be integrated into the housing. The sensor interface include a first sensor operable to take a plurality of physiological measurements of a user over a period of time. The processing device may be coupled to the sensor interface. The processing device may be operable to receive the plurality of physiological measurements; determine a change in the plurality of physiological measurements; and determine a hydration condition measurement for a body based on the change of the plurality of physiological measurements. The display device may be integrated into the housing. The display device may be operable to display a hydration condition indicator associated with the hydration condition measurement.

Abstract: A measurement circuit for measuring a property in a body comprises: a resonant circuit comprising a first element and a second element, where in at least one of the first element and the second element is configured such that a property thereof is dependent on the property in the body; and a non-linear element arranged to generate intermodulation products when the circuit is driven by an input signal comprising a first component at a first frequency and a second component at a second frequency. A measurement system for measuring a property in a body comprises: a measurement circuit as described above; a driving circuit for providing a driving signal to the measurement circuit, wherein the driving signal comprises a first component at a first frequency and a second component at a second frequency; and an analyzer circuit for analyzing a response of the measurement circuit in order to obtain a measurement of the property.

Abstract: A handbrake of a medical imaging apparatus that has a movable patient table with a top face on which a patient lies, fastens and releases the patient table when actuated. The handbrake with a mounting face and a first face has a main body and has a brake actuation button, operable in an actuation direction. The mounting face is attachable to the patient table. The front face is directly opposite to at least some parts of the mounting face in the actuation direction. The brake actuation button is disposed on the front face of the main body, and is actuated by pushing the brake actuation button in the actuation direction, in order to fasten or to release the brake of the patient table. The actuation direction is essentially perpendicular to the top face of the patient table.

Abstract: A backscatter approach is particularly customized for deep tissue devices, which do not require active signal transmission for localization of or data communication from the devices. The design overcomes interference from the body surface, and localizes the in-body backscatter devices even though the signal travels along non-straight paths. Data communication for the in-body device is also available using the approach.

Abstract: Aspects of the present disclosure are directed to the localization of an introducer sheath relative to an intravascular catheter. Further embodiments of the present disclosure are directed to the visualization of the introducer sheath on a graphical user interface of a navigation system.

Abstract: Methods and systems for position determination are described for using an intrabody probe having a plurality of electrodes to generate a plurality of different electrical fields, and to also measure, using the plurality of electrodes, a measurement set (a Ve-e measurement set) comprising a plurality of measurements of the plurality of different electrical fields while the probe remains in one position. From the Ve-e measurement set, spatial position coordinates for the intrabody probe are estimated within an intrabody coordinate system, using an established mapping between previously observed Ve-e measurement sets and positions in the intrabody coordinate system. Systems and methods for generating and selecting such mappings are also described.

Abstract: A method of estimating a ventilation rate in a room, the method comprising receiving a signal indicative of a concentration of at least one Volatile organic compound (VOC(t)) inside the room; processing the signal to detect at least one increase from an initial level (VOC(t0)) of the concentration of the at least one volatile organic compound; detect a corresponding maximum level of the concentration from the initial level; detecting when the concentration of the volatile organic compound returns towards the initial level or a steady state level (VOCss) from the corresponding maximum level; and determining the ventilation rate (k) based on the rate at which the concentration of the at least one Volatile organic compound returns towards the initial level or the steady state level from the corresponding maximum level.

Abstract: A spirometry system includes an imaging device configured to capture upper body movement images of a subject during inhalation and exhalation of the subject. The system further includes at least one controller configured to receive the captured images from the imaging device and, based upon the received images, determine at least one of an image-based spirometry flow-volume curve for the subject or an image-based spirometry parameter for the subject.

Abstract: Active auscultation may be used to determine organ (e.g., lung or heart) characteristics of users. An acoustic or piezo-electric signal (e.g., a pulse, a tone, and/or a broadband pulse) may be projected into an animal (typically human) body or thorax. The signal interacts with the body, or lungs, and in some cases may induce resonance within the body/lungs. A resultant signal may be emitted from the body which may be analyzed to determine, for example, a lung's resonant frequency or frequencies and/or how the sound is otherwise absorbed, reflected, or modified by the body. This information may be indicative of lung characteristics such as lung capacity, a volume of air trapped in the lungs, and/or the presence of COPD.

Abstract: A sulfide gas concentration measuring device comprises: an exhaled breath collection tool to be put to a subject to introduce exhaled breath of the subject into the exhaled breath collection tool; a pressure regulator comprising an inlet port connected to the exhaled breath collection tool; a sulfide gas sensor connected to an outlet port of the pressure regulator to measure a concentration of sulfide gas in the exhaled breath discharged from the outlet port; and a pressure measuring device. The pressure measuring device is configured to measure a pressure in the inlet port of the pressure regulator to make the subject aware of the measured pressure.

Abstract: A quantitative gait training and/or analysis system employs instrumented footwear and an independent processing module. The instrumented footwear may have sensors that permit the extraction of gait kinematics in real time and provide feedback from it. Embodiments employing calibration-based estimation of kinematic gait parameters are described. An artificial neural network identifies gait stance phases in real-time.

Abstract: A method for calculating an estimation of the speed {circumflex over (V)}[n?] of an individual walking along a path, over a time window including: computing a step length [n?] of the individual, calculating the speed {circumflex over (V)}[n?] using the following formula: {circumflex over (V)}[n?]=[n?]×[n?].

Abstract: A quantitative gait training and/or analysis system includes one or more footwear modules that may include a piezoresistive sensor, an inertial sensor and an independent logic unit. The footwear module functions to permit the extraction of gait kinematics and evaluation thereof in real time, or data may be stored for later reduction and analysis. Embodiments relating to calibration-based estimation of kinematic gait parameters are described.

Abstract: Various patient monitoring systems can include a sensor configured to collect three dimensional information. The systems can identify a location of a patient support surface based on the three dimensional information. The systems can set a two dimensional planar threshold based on the patient support surface. The systems can identify a patient location above the patient support surface based on the three dimensional information and compare the patient location to the two dimensional planar threshold. Exceeding the threshold can be indicative of a high risk of a patient fall. An alert can be generated based on the threshold being exceeded. The systems can repeat the identification of the patient support surface location and the setting of the threshold to account for changes in the patient area.

Abstract: Systems and methods for monitoring posture of a user wearing an exosuit are discussed herein. Exosuits worn by users can monitor several movement factors that characterize the user's movements and posture. The user's posture is identified and analyzed, and feedback is provided to the user based on the analyzed posture.

Abstract: The present application relates generally to computer software, mobile electronics, wireless communication links, and wearable monitoring systems. More specifically, techniques, fabrics, materials, systems, sensors, EMG sensors, circuitry, algorithms and methods for wearable monitoring devices and associated exercise apparatus are described. A garment borne sensor system may generate data on a user's performance during exercise, for example, and the data may be analyzed in real time and feedback may be provided to the user based on the analysis. A piece of exercise equipment may be instrumented and in communication with the sensor system or other system and may be controlled in real time to adjust its settings to affect the user during the exercise routine. Communication between the sensor system and other systems may be wireless. Conductive structures formed directly in a fabric of the garment may integrally include sensors, circuitry, controllers, conductive traces, and sensor electronics.

Abstract: Device and method for classifying the activity and/or counting steps of a user. A method for classifying the activity of a user can comprise measuring accelerometer data for a plurality of axes; identifying a most active one of the plurality of axes based on the accelerometer data; and classifying the activity of the user based on a signal amplitude of the accelerometer data for the most active axis and one or more threshold values.

Abstract: A system for validation of a hearing aid performance, especially in small children is disclosed. The validation of the performance of hearing aids after having being fitted to a small child who is not able to subjectively provide responses to sounds presented to the child via the hearing aids, is instead done in an objective manner, by using a naturally occurring signal, which has been modulated in order to create an ASSR evoking speech stimulus which is not considered as noise by a hearing aid.

Abstract: Vset-based systems and methods for performing sensor health diagnostics are disclosed. Methods and systems for in-body glucose sensor health diagnostics may use steady-state Isig characterization under full-range operating Vsets, transient Isig response characterization after Vset alternations, transient Vset characterization, and open circuit potential measurements for estimating sensor health and for monitoring sensor properties.

Abstract: An oxygen sensor is provided for measuring a dissolved oxygen concentration when deployed or implanted at a tissue site. The oxygen sensor includes a solid-state contrast agent for oxygen. The oxygen sensor is configured to indicate the dissolved oxygen concentration of a tissue when subjected to a magnetic resonance based method. The oxygen sensor may be used to map tumor oxygenation levels and for adaptive planning in brachytherapy.

Abstract: Glucose-sensing luminescent dyes, polymers, and sensors are provided. Additionally, systems including the sensors and methods of using these sensors and systems are provided.

Abstract: Disclosed are methods, apparatuses, etc. for determination and application of a metric for assessing a patient's glycemic health. In one particular implementation, a computed metric may be used to balance short-term and long-term risks associated with a particular therapy.

Abstract: A method is provided for constructing a structured test having user-defined adherence criteria. The method includes: presenting a patient with a plurality of contextual criterion for a structured test; receiving selection of one or more contextual criterion from the plurality of contextual criterion; and constructing a structured test that includes the contextual criterion selected by the patient. During administration of the structured test, each of the contextual criteria selected by the patient is evaluated. Sample data acquired during the structured test is reported as compliant when each of the context criterion selected by the patient was met during the administration of the structured test or tagged as non-compliant when at least one contextual criterion was not met during the administration of the structured test.

Abstract: Apparatus and methods for reducing error due to spatial arrangement of sensor elements in a parameter sensor such as a physiologic analyte sensor. In one exemplary embodiment, the analyte sensor is configured to measure an analyte of a living being (e.g., blood glucose), and the apparatus and methods employ determination of a blood analyte concentration based on a prescribed relationship of N1/N2—i.e., N1 analyte modulated sensing elements (e.g., glucose electrodes) associated with and proximate to N2 background sensing elements of the sensor—in order to compensate for response differences due to spatial arrangement of the sensor elements or “spatial mismatch.” This configuration of sensor elements and method of determining blood analyte concentration (based on multiple background signal electrodes) enables increased accuracy of the sensor.

Abstract: The present disclosure is directed to enhanced sampling of bioanalytes from bodily fluids using wearable and/or insertable devices. In some embodiments, an apparatus (100, 500, 600) for sampling bioanalyte(s) in tissue (107, 507, 607) may include: a base (102, 502, 602) having conduit(s) adapted to receive fluid extracted from the tissue; microneedles (106, 306, 506, 606) fluidly coupled with the conduit(s) and adapted to be pierced into the tissue; a plurality of individually-controllable energy emitters (112, 114, 350, 612, 614); and logic (90) operably coupled with the plurality of individually-controllable energy-emitters. The logic may be adapted to operate a subset of the plurality of individually-controllable energy emitters to apply energy at a first subset of the microneedles to induce bioanalyte flow through tissue towards the first subset or a second subset of the microneedles, or through the first subset or a second subset of the microneedles.

Abstract: An electronic device for providing biometric information is provided. The electronic device includes a sensor module, a memory, and a processor electrically connected to the sensor module and the memory. The processor obtains a biometric signal from the sensor module at a predetermined time interval, determines whether a user is in a first state on the basis of the obtained biometric signal, in case the user is in a first state, obtains a representative value for a respective of the at least one biometric signal, defines the obtained representative value for the respective of the at least one biometric signal as a candidate reference value for a corresponding biometric signal, determines a candidate reference value satisfying a predetermined condition as a first reference value for the corresponding biometric signal, and updates a second reference value previously configured for the corresponding biometric signal on the basis of the first reference value.

Abstract: This invention relates generally to the field of electronic communications and the transmittance of such communications. More specifically, the invention discloses a new and useful method for delivering a therapeutic through an eco-system of digital content based on a user-mapped EMS. The method comprises: receiving a text input comprising message content from an electronic computing device associated with a user; parsing the message content comprised in the text input for emotionally-charged language; assigning a sentiment value, based on the emotionally-charged language, from a dynamic sentiment value spectrum to the text input; and, based on the sentiment value, imposing a sentiment vector, corresponding to the assigned sentiment value, to the text input, the imposed sentiment vector rendering a sensory effect on the message content designed to convey a corresponding sentiment.

Abstract: A monitoring device comprising at least one measurement module for measuring at least one physiological parameter of the crew member, at least one consolidation module for consolidating the measured physiological parameter or parameters, a fusion module for fusing the consolidated physiological parameter or parameters in order to detect at least one physiological status of the crew member, a filtering module for filtering the physiological status or statuses, a determination module for determining a level of incapacity of the crew member, a transmission module for transmitting a signal indicative of the level of incapacity of the crew member to a user device.

Abstract: An operation aptitude judgment device includes a perception difficulty space detection unit that detects a perception difficulty space in which a perception object as an object that the user should perceive when the user performs a planned operation is difficult for the user to perceive based on vicinal object information acquired from a vicinal object detection device that detects a vicinal object existing in a vicinity of the user; a user perception movement detection unit that detects a user perception movement, as a movement of the user when the user tries to perceive the perception object, based on user movement information acquired from a user movement detection device that detects a movement of the user; and an operation aptitude level calculation unit that calculates the operation aptitude level of the user based on the perception difficulty space and the user perception movement.

Abstract: A vehicular notification apparatus detects an emotion of a driver based on a line-of-sight detection result and a brain activity detection result, and performs control to suppress notification in response to that the detected emotion of the driver is uncomfortable.

Abstract: A device for monitoring body fluid discharge almost in real time is provided, the device includes a base, a motor, a catheter holder, and a liquid level sensor. The motor is fixed on the base and includes an output shaft. The catheter holder is connected to the output shaft and is rotatable relative to the base by the output shaft. The catheter holder includes a curved holding chamber with two openings containing a catheter. The liquid level sensor is disposed at one of the openings for detecting a liquid level of body fluid in the catheter and such level is recorded when a fully-filled catheter is automatically tipped and emptied into a collecting bag. A method for monitoring body fluid discharge using the device is also provided.

Abstract: Systems and methods for analyzing sublingual microcirculation perfusion and identifying particular nerve tracts. In exemplary embodiments, a digital micro-mirror device is configured to direct a reflected light to a subject area and a controller is configured to alter a parameter of the reflected light.

Abstract: A method for detecting allergic reaction and alerting a guardian device includes registering a wearable device to associate the wearable device with the guardian device. The wearable device then monitors vital signs to determine whether the vital signs are within an acceptable range. Based on the vital signs being outside the acceptable range, the wearable device sends an alert to the guardian device and determines whether a confirmation signal is received from the guardian device.

Abstract: Embodiments facilitate predicting a patient prostate cancer (PCa) DECIPHER risk group. A first set of embodiments relates to training of a machine learning classifier to compute a probability that a patient is a member of a DECIPHER low/intermediate risk group based on radiomic features extracted from bi-parametric magnetic resonance imaging (bpMRI) images. A second set of embodiments relates to classifying a patient as a member of DECIPHER low/intermediate risk group, or DECIPHER high-risk group, based on radiomic features extracted from bpMRI imagery of the patient.

Abstract: In various exemplary embodiments, a method for determining a degree of colonization of skin with acne bacteria is provided. The method may comprise: for at least one region of a user's skin, recording an image of the region of skin by a camera during illumination of the region of skin with ultraviolet and/or blue light, wherein the camera is configured to at least capture light in a fluorescence wavelength range of a fluorescent agent produced by the acne bacteria, by the image, determining a captured quantity of light which is emitted from the fluorescent agent as fluorescence as a consequence of the illumination, and allocating a degree of colonization of the skin to the determined captured quantity of light, wherein the allocation of the degree of colonization of the skin to the determined captured quantity of light is carried out by a database stored in cloud computing architecture.

Abstract: Systems and methods for accurately and efficiently diagnosing, assessing, staging/grading/categorizing, and treating pressure ulcers, as well as preventing reverse staging of pressure ulcers, are disclosed. The system, in one embodiment, ensures that the rationale for the stage assigned to the patient will be in the patients' medical record. The system, in various embodiments, further suggests the pressure ulcer classification and allows the user to choose which classification terms should be used. In various embodiments, the system also allows for the different classification/staging system guidelines to be used, including the National Pressure Ulcer Advisory Panel (NPUAP) guidelines, the European Pressure Ulcer Advisory Panel Guidelines (EPUAP), the Pan Pacific Pressure Injury Alliance, CMS, WHO, and the MDS Guidelines.

Abstract: The invention relates to a method of determining the laxity of a joint (9, 15) of a human (5) or an animal. The method comprises providing at least one patient-specific geometrical model (1) of at least one bone and/or at least one prosthesis comprised by the joint. Known loads are applied to the joint or to a part of the body connected to the joint, and a series of actual images (16) of the joint are obtained while the loads are applied. Then the at least one patient-specific geometrical model (1) is registered onto the actual images (16). Based thereon relative displacement and/or rotation of the at least one bone and/or at least one prosthesis is calculated as a function of the applied loads, and based thereon a measure of the laxity of the joint is determined. The invention further relates to a system for performing such a method and to a computer readable medium for performing such a method.

Abstract: A computing system having at least one sensor, at least one processor, and at least one memory including a plurality of instructions stored thereon that, in response to execution by the at least one processor, causes the computing system to receive one or more surgical parameters associated with a ligament balancing of a patient's joint, receive real-time sensor data generated by the at least one sensor and indicative of at least one characteristic of the patient's joint, and apply machine learning to determine a next ligament balancing step of the ligament balancing of the patient's joint based on the one or more surgical parameters and the real-time sensor data, wherein the next ligament balancing step is a step of one or more steps intended to result in a target state of the patient's joint identified by the machine learning.