Patents Issued in January 30, 2020
  • Publication number: 20200030483
    Abstract: The present invention relates to a soft tissue adhesive comprising an aqueous composition comprising ?-TCP and a phosphorylated amino acid. The composition has improved mechanical strength and is easily applied to the tissue.
    Type: Application
    Filed: September 27, 2017
    Publication date: January 30, 2020
    Inventors: Philip PROCTER, Håkan ENGQVIST, Michael PUJARI-PALMER, Gerard INSLEY
  • Publication number: 20200030484
    Abstract: Disclosed are: a composition for hard tissue repair with excellent penetrability to an adherend such as a cancellous bone and excellent adhesion to an adherend, which comprises a monomer (A), a polymer powder (B) comprising 54% by mass or more of a polymer powder (b1) having a volume mean particle diameter of 27 to 80 ?m and a polymerization initiator (C); and a kit for hard tissue repair comprising members in which the components of the monomer (A), the polymer powder (B) and the polymerization initiator (C) contained in this composition for hard tissue repair are encased in three or more divided groups in an optional combination.
    Type: Application
    Filed: March 29, 2018
    Publication date: January 30, 2020
    Applicant: Mitsui Chemicals, Inc.
    Inventors: Kengo GOTO, Shinya AOKI, Takashi MIURA, Tetsuya HAMADA, Ayako BANDO
  • Publication number: 20200030485
    Abstract: Disclosed are: a composition for hard tissue repair with excellent penetrability to an adherend such as a cancellous bone and excellent adhesion to an adherend, which comprises a monomer (A), a polymer (B), a polymerization initiator (C) and a contrast medium (X) having a volume mean particle diameter of 3 ?m or more; and a kit for hard tissue repair having members in which the components of the monomer (A), the polymer (B), the polymerization initiator (C) and the contrast medium (X) contained in this composition for hard tissue repair are encased in three or more divided groups in an optional combination.
    Type: Application
    Filed: March 29, 2018
    Publication date: January 30, 2020
    Applicant: Mitsui Chemicals, Inc.
    Inventors: Shinya AOKI, Kengo GOTO, Takashi MIURA, Tetsuya HAMADA, Ayako BANDO
  • Publication number: 20200030486
    Abstract: A method of forming a fibrin hydrogel composition including providing one or more unitary masses of a fibrin hydrogel, dividing at least one of the unitary masses of the fibrin hydrogel into a multiplicity of smaller pieces of the fibrin hydrogel, and recombining at least a portion of the smaller pieces into a cohesive mass. Dividing at least one of the unitary masses of fibrin hydrogel into a multiplicity of smaller pieces may include shearing or cutting the unitary masses to form an aqueous dispersion of the fibrin hydrogel in an aqueous medium. The aqueous dispersion of fibrin hydrogel may be applied to a substrate on a roller or an endless belt, and is optionally overlaid by a scrim. The cohesive mass of fibrin hydrogel, which may be formed by removing at least a portion of the aqueous medium from the aqueous dispersion of the smaller pieces of the fibrin hydrogel, finds uses in wound dressing articles.
    Type: Application
    Filed: October 3, 2017
    Publication date: January 30, 2020
    Inventors: Jonathan J. O'HARE, Mikhail L. PEKUROVSKY, Amy S. DETERMAN, Gino L. PITERA, Jason W. BJORK, Daniel V. NORTON, Robert A. ASMUS
  • Publication number: 20200030487
    Abstract: Provided is an antibacterial biological implant capable of exhibiting superior antibacterial activity stably over a long period of time. Also provided is a method for producing an antibacterial biological implant, the method including subjecting a substrate 2 successively to an anodization treatment, an acid treatment, and an iodine treatment to obtain an antibacterial biological implant 1.
    Type: Application
    Filed: March 31, 2017
    Publication date: January 30, 2020
    Applicant: PROSTEC CO., LTD.
    Inventors: Hiroyuki TSUCHIYA, Yukinobu HASHIMOTO
  • Publication number: 20200030488
    Abstract: A method of coating a peptide or protein useful for improving the cellular activity related to bone growth on an inorganic particle comprises the steps of freezing the residual liquid present on uncoated and or coated inorganic particles, and drying the uncoated or coated inorganic particles after freezing the residual liquid, the drying comprising causing the frozen residual liquid to sublime under vacuum. Further disclosed embodiments of the invention include further processes for forming inorganic particles coated with a peptide or protein useful for improving cellular activity related to bone growth and medical devices comprising the coated particles.
    Type: Application
    Filed: February 21, 2019
    Publication date: January 30, 2020
    Inventors: Jevon NYEMSCEK, Jessica STUFFLET, Nicolas ROSCIOLI, Doug MILLARD, Katherine Suzanne DAVIS, Nolan Chase HANNIGAN, Tristan Stuart BARNES, Jerome CONNOR
  • Publication number: 20200030489
    Abstract: A one-step formed gel fiber composite scaffold material can be prepared by preparing an electrospun film through a high-voltage electrostatic method and soaking the electrospun film into a phase separation solution to obtain the gel fiber composite scaffold material.
    Type: Application
    Filed: January 25, 2017
    Publication date: January 30, 2020
    Inventors: Xinxiao HAN, Dong HAN
  • Publication number: 20200030490
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen.
    Type: Application
    Filed: October 8, 2019
    Publication date: January 30, 2020
    Inventors: Xiaojie Yu, Nicholas J. Manesis, Jacob Pollock
  • Publication number: 20200030491
    Abstract: A method for manufacturing a bioactive implant including the steps of (a) forming a mixture of an bioactive agent and a setting agent capable of transitioning from a flowable state to a rigid state; (b) converting the mixture into a flowable state; and (c) transitioning the mixture into a solid state in a shape of the implant.
    Type: Application
    Filed: October 1, 2019
    Publication date: January 30, 2020
    Inventors: Jeffery Adam Weisman, James Connor Nicholson, David Mills
  • Publication number: 20200030492
    Abstract: The invention provides a three dimensional (3D), porous, biodegradable and biocompatible tissue engineering scaffold, wherein at least 25% w/w of the scaffold is particulate egg shell membrane (ESM) distributed substantially uniformly therein and the scaffold is essentially dry. Methods for preparing the same by freeze-drying and cryogelation and the use thereof in methods of tissue engineering and to promote the healing of wounds are also provided.
    Type: Application
    Filed: June 24, 2016
    Publication date: January 30, 2020
    Inventors: ENDA KENNY, RALF SCHMIDT, HENRI-PIERRE SUSO
  • Publication number: 20200030493
    Abstract: Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Inventors: Stephen F. Badylak, Donald Freytes
  • Publication number: 20200030494
    Abstract: Particles made of a viscoelastic medium, are injectable gel particles, and have a size, when subjected to a physiological salt solution, in the range of from 1 to 5 mm. The particles are useful in a soft tissue augmentation implant. The implant includes particles of a viscoelastic medium, wherein a major volume of the particles are injectable gel particles The implant is useful in a method of soft tissue augmentation in a mammal, including man, comprising subepidermal administration at a site in said mammal where soft tissue augmentation is desirable, of an implant.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Applicant: NESTLÉ SKIN HEALTH S.A.
    Inventor: Bengt ÅGERUP
  • Publication number: 20200030495
    Abstract: An injectable hydrogel composition that forms a porous gel rapidly after injection fro tissue engineering. The composition comprises a biodegradable, biocompatible, gelling polymer, that is optionally reverse-gelling; an Extra cellular matrix (ECM) material and a biocompatible porogen. Methods of making and using the composition are provided. A kit also is provided comprising the ingredients for making the hydrogel.
    Type: Application
    Filed: April 3, 2018
    Publication date: January 30, 2020
    Inventors: Stephen F. Badylak, Hong Jiang, Hideyoshi Sato, William R. Wagner, Yang Zhu
  • Publication number: 20200030496
    Abstract: A soft tissue device can incorporate a composite material comprising a gel and at least one nanostructure disposed within the gel. A soft tissue device can further incorporate biologically active materials such as cells, tissues. A method for healing a soft tissue defect while promoting soft tissue regeneration can include applying a soft tissue device to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a soft tissue device for use in healing soft tissue defects can include providing a gel, disposing nanofibers within the gel, and a biologically active material.
    Type: Application
    Filed: July 18, 2019
    Publication date: January 30, 2020
    Inventors: Sashank Reddy, Russell Martin, Xiaowei Li, Calvin Chang, Kevin Colbert, Hai-Quan Mao
  • Publication number: 20200030497
    Abstract: A multilayer film for ostomy and bowel management applications includes a barrier layer comprising at least about 90% wt. nylon 6/69. The multilayer film provides excellent mechanical and odor barrier properties, and softness and quietness desired in ostomy and bowel management applications.
    Type: Application
    Filed: October 1, 2019
    Publication date: January 30, 2020
    Inventors: Moh-Ching Oliver Chang, George J. Cisko
  • Publication number: 20200030498
    Abstract: Generally, the invention is in relation to the field of drug delivery devices to augment standard radiation therapy and methods of making and using same. Specifically, this technology utilizes a controlled release of drug from a coated balloon for local intratumoral drug delivery to breast tissue to supplement or replace standard radiation therapy.
    Type: Application
    Filed: December 19, 2017
    Publication date: January 30, 2020
    Inventor: Ronald E. Betts
  • Publication number: 20200030499
    Abstract: Compositions containing chlorhexidine gluconate solubilized in hydrophobic vehicles are described. Resin systems containing such chlorhexidine gluconate compositions, including adhesives and articles incorporating such resin systems, including medical articles such as drapes are also described.
    Type: Application
    Filed: October 2, 2019
    Publication date: January 30, 2020
    Applicant: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: VINOD P. MENON, JOSEPH D. RULE, RICHARD B. ROSS, DEENA M. CONRAD-VLASAK, KATIE F. WLASCHIN
  • Publication number: 20200030500
    Abstract: Systems, devices, and methods for treating a tissue site on a patient with reduced pressure are presented. In one instance, a reduced-pressure treatment device to treat a tissue site with reduced pressure may include a pump control unit fluidly separate from a collection unit. Pump energy may be provided by the pump control unit to deflect one or more diaphragms within the collection unit to create reduced pressure. Other systems, devices, and methods are presented.
    Type: Application
    Filed: August 26, 2019
    Publication date: January 30, 2020
    Inventors: Christopher Brian LOCKE, Aidan Marcus TOUT, Timothy Mark ROBINSON
  • Publication number: 20200030501
    Abstract: A method and system for separating a flow of matter is shown and described. The system includes one or more flow separation devices, one or more surgical instruments, and one or more suction sources. In some embodiments, the flow of matter comprises biological material. In some embodiments, the flow of matter comprises surgical waste.
    Type: Application
    Filed: September 11, 2019
    Publication date: January 30, 2020
    Applicant: CONMED CORPORATION
    Inventor: Noah Mark Minskoff
  • Publication number: 20200030502
    Abstract: A device for clearing obstructions from a medical tube includes an enclosure having an interior and an exterior, the enclosure comprising a distal opening for providing access to the interior of the enclosure. The device further includes a spool provided within the enclosure that is rotatable about an axis and an elongated guide member coupled to the spool such that rotation of the spool causes the guide member to wind or unwind about the spool. The device further includes a drive mechanism that is operable to rotate the spool within the enclosure without compromising a sterile field within the enclosure.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Inventors: KATHRYN BERNADINE O'KEEFE, STEPHEN RIDDLE MCDANIEL, EDWARD M. BOYLE, JR., KENNETH ALLAN BERES, MATTHEW CHRISTOPHER BARRA, THOMAS URBANIK, CHELSEA ANN GAMMON, KENNETH J. CHESNIN
  • Publication number: 20200030503
    Abstract: Systems and methods are provided for collecting a platelet product from a fluid including platelets and plasma. Platelet-rich plasma is separated from at least a portion of another constituent of the fluid and then may be further separated into concentrated platelets and platelet-poor plasma, with the concentrated platelets being resuspended. Separated platelets (in the form of platelet-rich plasma or resuspended platelets) are conveyed through a size exclusion filter and into a platelet storage container. The size exclusion filter is configured to remove platelet clumps and/or particles larger than a platelet from the separated platelets. Subsequently, an additive is conveyed through the size exclusion filter and into the platelet storage container. Conveying additive through the size exclusion filter improves platelet recovery in the platelet product by displacement of separated platelets with the additive and may also break up any platelet clumps that are present in the size exclusion filter.
    Type: Application
    Filed: April 20, 2017
    Publication date: January 30, 2020
    Inventors: Katherine N. Radwanski, Kyungyoon Min
  • Publication number: 20200030504
    Abstract: A blood component collection cassette that can trap a foreign object such as a blood-coagulated clot from blood components to be returned to a blood donor and a manufacturing method of the blood component collection cassette are provided. A sheet-shaped filter member (60) is arranged on a flow path (42) in a cassette main body (40) of a blood component collection cassette (28). A first tube (66) and a second tube (68) are arranged in the cassette main body (40). An inner space (51) of a filter housing unit (54a) is separated by the filter member (60) into a first space (51a) on the side of the first tube (66) and a second space (51b) on the side of the second tube (68).
    Type: Application
    Filed: March 20, 2018
    Publication date: January 30, 2020
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Masatsugu IGARASHI
  • Publication number: 20200030505
    Abstract: A blood component collection cassette that can trap a substance where blood components coagulate by using a simple and economical configuration, and a manufacturing method of the blood component collection cassette are provided. A blood component collection cassette (28) includes a cassette main body (40) where a flow path (42) is formed and is configured to be mountable to a centrifugal separation device (14). The cassette main body (40) has a first sheet (40a) and a second sheet (40b) which are formed of a soft material. The flow path (42) is formed between the first sheet (40a) and the second sheet (40b). A filter member (60) for trapping a substance where blood components coagulate is arranged on the flow path (42) in the cassette main body (40).
    Type: Application
    Filed: March 20, 2018
    Publication date: January 30, 2020
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Masatsugu IGARASHI
  • Publication number: 20200030506
    Abstract: A breast pump apparatus, the apparatus comprising at least one collection unit, a pump, the pump comprising a piston, and a chair, wherein the collection unit is in fluid communication with the pump, such that upon actuation the pump creates suction impulses which are transmitted, in use, to the user's breast via the collection unit, thereby expressing milk from the breast into the collection unit, and wherein the pump is connected to the chair, such that, in use, the relative movement of a first portion of the chair relative to the other parts of the chair, manually actuates and drives the piston of the pump.
    Type: Application
    Filed: September 27, 2017
    Publication date: January 30, 2020
    Inventors: Nicholas Paget, Matt Batchelor, Natalie Vanns, Graham Hodge
  • Publication number: 20200030507
    Abstract: The present invention provides an intravascular blood pump comprising an impeller housing and/or impeller blade(s) that may be expandable and collapsible. The blade(s) and/or impeller housing may be biased to expand or may be expanded by centrifugal forces generated during rotation of the impeller and blades with an operatively connected rotational motor.
    Type: Application
    Filed: July 29, 2019
    Publication date: January 30, 2020
    Inventors: Joseph P. Higgins, Jeffrey R. Stone
  • Publication number: 20200030508
    Abstract: An implantable pump is configured to be implanted in series with blood flow from a heart. The pump includes a frame configured to be implanted within the natural blood flow of the heart such as a ventricular outflow tract an outlet valve of the heart, and a central axle configured to be affixed within the frame parallel to the blood flow. The pump also includes a rotor attached to the central axle and configured to rotate in order to pump blood, and at least two electromagnetic coils configured to be energized in order to cause the rotor to rotate.
    Type: Application
    Filed: July 30, 2019
    Publication date: January 30, 2020
    Inventor: Michael SIEGENTHALER
  • Publication number: 20200030509
    Abstract: Blood pump for percutaneous insertion into a heart's ventricle comprising an electrical motor for driving the blood pump, the electrical motor comprising at least tree motor winding units, wherein each motor winding unit is individually connectable to a power supply via two separate phase supply lines connected to the respective motor winding unit terminals. Motor controller for driving and controlling the electrical motor of the blood pump, wherein the motor controller comprises corresponding phase supply line driving units for each motor winding units of the electrical motor of the blood pump which phase supply line driving units are connected via the corresponding two phase supply lines with the corresponding motor winding unit. Blood pump system comprising the blood pump and the motor controller.
    Type: Application
    Filed: February 5, 2018
    Publication date: January 30, 2020
    Inventors: Thorsten Siess, Christof Malzkorn, Martin Kortyka, Christian Moser
  • Publication number: 20200030510
    Abstract: The present invention provides an intravascular blood pump comprising a pump assembly without a flow inducer or diffuser, and proximal and distal flow rate or pressure sensors, wherein the distal flow rate or pressure sensor may be tracked distal to the impeller after placement of the blood pump within the patient's vasculature.
    Type: Application
    Filed: July 29, 2019
    Publication date: January 30, 2020
    Inventor: Joseph P. Higgins
  • Publication number: 20200030511
    Abstract: The present invention provides an intravascular blood pump comprising a housing that is at least partially expandable and collapsible and having an impeller with one or more blades attached thereto. The housing having spanning sections that are aligned with the blade(s) and adapted to collapse into recesses or spaces defined or provided between or along the blade(s) and along the central rotor to which the blade(s)s are attached.
    Type: Application
    Filed: July 29, 2019
    Publication date: January 30, 2020
    Inventor: Joseph P. Higgins
  • Publication number: 20200030512
    Abstract: The present invention provides an intravascular blood pump comprising a housing region that may be expandable and collapsible, wherein the expandable housing region includes the inlet to the pump and wherein the distal diameter of the expandable housing region, including the inlet, is larger than a proximal diameter of the expandable housing region. A non-expandable region may be provided and disposed between the expandable housing region and the pump assembly of the intravascular blood pump.
    Type: Application
    Filed: July 29, 2019
    Publication date: January 30, 2020
    Inventors: Joseph P. Higgins, Matthew W. Tilstra, Benjamin D. Haselman, Matthew D. Cambronne, Tristan A. Van de Moortele
  • Publication number: 20200030513
    Abstract: In general, a dialysis device includes a first processing device for monitoring dialysis functions of the dialysis device, a second processing device, a display device, and memory. The memory is configured to store instructions that, when executed, cause the dialysis device to provide, on the display device, a first display region and a second display region, where the first display region is associated with the first processing device and the second display region is associated with the second processing device. At least a portion of the first display region cannot be obscured by the second display region.
    Type: Application
    Filed: October 3, 2019
    Publication date: January 30, 2020
    Inventors: Fei Wang, Martin Joseph Crnkovich, Roland Levin, Michael Emmanuel Kotsos
  • Publication number: 20200030514
    Abstract: A dialysis system is provided that includes a dialysis machine and a potassium sensing device that is configured to measure the concentration of potassium in the patient's blood, in spent dialysate resulting from treating the patient, or in both. The potassium sensing device can be configured to generate a sensed value of the concentration of potassium. A control and computing unit, including a processor and a memory, is configured to receive the sensed value, compare the value with one or more values stored in the memory, and generate a control signal based on the comparison. A potassium infusion circuit uses the control signal to infuse supplemental potassium solution into the treatment dialysate, a replacement fluid, or both. The memory can include stored patient-historical and population data.
    Type: Application
    Filed: July 24, 2019
    Publication date: January 30, 2020
    Inventors: Stephen Merchant, Roland Levin, Chris Chau, Shakil Aslam
  • Publication number: 20200030515
    Abstract: A method of dialysis is provided that includes sensing the concentration of potassium in a patient's blood serum, in used dialysate resulting from treating the patient, or in both. The method involves generating a sensed value of the concentration of potassium, comparing the sensed value with one or more values stored in a memory, and generating a control signal based on the comparison. Supplemental potassium solution is infused into the treatment dialysate, based on the control signal. The comparison can be made to patient-historical data, population data, or both.
    Type: Application
    Filed: July 24, 2019
    Publication date: January 30, 2020
    Inventors: Stephen Merchant, Roland Levin, Chris Chau, Shakil Aslam
  • Publication number: 20200030516
    Abstract: A system includes a device having a blood side, a solution side, and a semipermeable membrane structurally configured for diffusion of one or more solutes therethrough. The system also includes a first extracorporeal circuit having one or more first fluid connectors for connecting the blood side of the device to the vascular system of a first animal, a second extracorporeal circuit including one or more second fluid connectors for connecting the solution side of the device to the vascular system of a second animal, a first pump in fluid communication with at least one of the first and second extracorporeal circuits, and a driver mechanically coupled to the first pump, the driver configured to drive the first pump using energy from an energy source.
    Type: Application
    Filed: October 1, 2019
    Publication date: January 30, 2020
    Inventors: Peter Kotanko, Stephan Thijssen
  • Publication number: 20200030517
    Abstract: Peritoneal dialysis, such as automated peritoneal dialysis (“APD”) is provided with any one or more or all of the following sensing or feedback features: impedance sensing to detect peritonitis, temperature sensing to detect peritonitis, bio-MEMS sensing to detect peritonitis, and glucose control for diabetes patients, wherein each sensing or feedback feature analyzes patient effluent fluid or fluid dwelling within a patient's peritoneal cavity.
    Type: Application
    Filed: July 25, 2019
    Publication date: January 30, 2020
    Inventors: Sukhraaj Basati, Shantanu Avinash Gadre, Mohammad Ali Jamnia, Lakshmy M. Nair, William J. O'Reilly, Marta Wlodarczyk
  • Publication number: 20200030518
    Abstract: An external support that routes the tubing of a reversing valve in such a manner that connection tubes extend from one end of the device and the treatment device tubes extend from the opposite end. The external support may provide guides that hold the tubing extending from the supported flat rotary switch type of valve so as to keep them from being pinch or kinked thereby ensuring free flow of blood.
    Type: Application
    Filed: March 26, 2018
    Publication date: January 30, 2020
    Applicant: NxStage Medical, Inc.
    Inventors: James M. BRUGGER, William J. SCHNELL, Kenneth E. BUCKLER
  • Publication number: 20200030519
    Abstract: The present invention relates to a method for removing a first fluid from a blood filter for the blood treatment of a patient and/or for removing blood from the blood filter after completing the blood treatment session. It further relates to a medical treatment apparatus having a control device with which a method for removing a first fluid from a blood filter is executable, a digital storage medium, and a computer program product.
    Type: Application
    Filed: October 2, 2019
    Publication date: January 30, 2020
    Inventors: Jürgen Häcker, Sören Gronau
  • Publication number: 20200030520
    Abstract: Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.
    Type: Application
    Filed: July 26, 2019
    Publication date: January 30, 2020
    Applicant: Terumo BCT Biotechnologies, LLC
    Inventors: Jon A. DODD, Daniel R. CLEMENT, Dennis J. HLAVINKA, Jeremy T. PARSONS, Haralambos P. APOSTOLOPOULOS
  • Publication number: 20200030521
    Abstract: A rectal drainage appliance is disclosed comprising a tubular element having an inflatable balloon at a distal end for anchoring the appliance in the rectum. The appliance includes one or more of: (i) first and second auxiliary lumens communicating with the inflatable balloon to provide independent inflation and pressure monitoring paths coupled to the balloon; (ii) a pressure state indicator defined by a mechanical element configured to flip between first and second states or shapes responsive to sensed pressure; and (iii) a collapsible auxiliary lumen larger than the inflation lumen, and configured to permit admission of irrigation fluid. The pressure state indicator may also be used in intestinal drains.
    Type: Application
    Filed: September 9, 2019
    Publication date: January 30, 2020
    Inventor: Christopher GREGORY
  • Publication number: 20200030522
    Abstract: A nuclear medicine infusion system (10) may be used to generate and infuse radioactive liquid into a patient undergoing a diagnostic imaging procedure. In some examples, the infusion system includes a frame (30) that carries a radioisotope generator (52) that generates radioactive eluate via elution. The frame may also carry a beta detector (58) and a gamma detector (60). The beta detector can be positioned to measure beta emissions emitted from the radioactive eluate supplied by the generator. The gamma detector can be positioned to measure gamma emissions emitted from a portion of the radioactive eluate to evaluate a safety of the radioactive eluate delivered by the infusion system.
    Type: Application
    Filed: September 20, 2017
    Publication date: January 30, 2020
    Inventors: Clif MOYERS, Adrian NUNN, Andrew SCHIMMOELLER, Brian CHERUNDOLO
  • Publication number: 20200030523
    Abstract: An infusion system may include a strontium-rubidium radioisotope generator that generates a radioactive eluate via elution, a beta detector, a gamma detector, and a controller. The beta detector and the gamma detector may be positioned to measure beta emissions and gamma emissions, respectively, emitted from the radioactive eluate. In some examples, the controller is configured to determine an activity of rubidium in the radioactive eluate based on the beta emissions measured by the beta detector and determine an activity of strontium in the radioactive eluate based on the gamma emissions measured by the gamma detector.
    Type: Application
    Filed: September 20, 2017
    Publication date: January 30, 2020
    Inventors: Adrian NUNN, Clif MOYERS, Andrew SCHIMMOELLER, Brian CHERUNDOLO, Tarah BOLAS
  • Publication number: 20200030524
    Abstract: A chemical liquid injector that can easily set various injection conditions according to a region and an objective to be imaged. The chemical liquid injector includes two piston driving mechanisms for operating syringes filled with a first chemical liquid and a second chemical liquid, respectively, an input unit for receiving an input of a data, and an injection control unit for controlling an operation of the piston driving mechanisms. The injection control unit is set with a multistage injection mode in which injection operations are performed in a plurality of injection phases.
    Type: Application
    Filed: April 11, 2018
    Publication date: January 30, 2020
    Inventors: Shigeru NEMOTO, Tsuyoshi SAITO
  • Publication number: 20200030525
    Abstract: An inverted battery device has a pair of electrodes, first and second volumes, and an electrical conductor. One of the pair of electrodes is configured as an anode and the other is configured as a cathode. A first electrolyte solution and the anode are disposed in the first volume, while a second electrolyte solution and the cathode are disposed in the second volume. The electrical conductor extends between the first and second volumes to couple the pair of electrodes to each other such that electrons travel between the pair of electrodes. The device is constructed to produce ions rather than electrons such that an ionic current can be generated in a separate system, such as a biological system or other ionic system, when coupled between the anode and cathode.
    Type: Application
    Filed: July 23, 2019
    Publication date: January 30, 2020
    Inventors: Liangbing HU, Chengwei WANG
  • Publication number: 20200030526
    Abstract: An Infusion device (1) for administering a medical fluid to a patient, comprises: a housing (10); a receptacle (11) arranged on the housing (10) for receiving a syringe (2); a pusher device (12) movable in a pushing direction (P) for acting onto a piston (21) of a syringe (2) received on the receptacle (11); a drive element (13) connected to the pusher device (12), the drive element (13) being longitudinally movable relative to the housing (10) for moving the pusher device (12) along the pushing direction (P); a driving rod (14) having a screw thread (140) and being rotatable about a rotational axis (R1); an electric drive device (141) for rotating the driving rod (14); a clutching device (130) connected to the drive element (13) and being actuatable, by an actuation device (15), to engage, in a clutched state, with the screw thread (140) of the driving rod (14) for translating a rotational movement of the driving rod (14) into a longitudinal movement of the drive element (13) along the driving rod (14), and
    Type: Application
    Filed: September 30, 2016
    Publication date: January 30, 2020
    Inventor: Rémy Wolff
  • Publication number: 20200030527
    Abstract: A surgical fluid management system includes a console and a cassette for delivering fluids to a surgical site. The console has a pump rotor and a pressure-sensing membrane. The cassette has a cassette housing, a flexible fluid delivery tube in the housing. The flexible fluid delivery tube has a lumen configured to interface with the pump rotor and to deliver a flow of fluid from a fluid source as the rotor is rotated. A pressure-transmitting membrane is located in a wall of the cassette housing and in fluid communication with said fluid delivery lumen,. The pressure-transmitting membrane flexes outwardly in response to a positive pressure in the lumen and flexes inwardly in response to a negative pressure in the lumen. The pressure-transmitting membrane detachably adheres to or presses against the pressure-sensing membrane to cause the pressure-sensing membrane to move in response to pressure changes in the flexible fluid delivery tube.
    Type: Application
    Filed: June 7, 2019
    Publication date: January 30, 2020
    Applicant: Hermes Innovations LLC
    Inventors: Akos Toth, Csaba Truckai
  • Publication number: 20200030528
    Abstract: An implantable drug delivery device and method that includes a sensor device for detecting deflection of a diaphragm at a first time from a first position within a diaphragm chamber of an accumulator of the implantable drug delivery device. A cycle count may be incremented in response to the diaphragm returning to the first position within the diaphragm chamber, each time during cyclical deflections within the diaphragm chamber. A flow rate of infusate may be determined based on a volume of the diaphragm chamber, the cycle count, and an elapsed time since the first time. Once the flow rate is determined, a processor may determine whether the flow rate of infusate is normal based on a comparison of the determined flow rate to at least one threshold flow rate.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Inventors: Paul BURKE, Steve ADLER, Robert Lash
  • Publication number: 20200030529
    Abstract: Subcutaneous access hub embodiments are discussed herein that include housing embodiments having a plurality of cannula ports and a fluid passageway network that allows fluid communication between a fluid source and the plurality of cannula access ports. Such a configuration may allow a user such as a patient or clinician to releasably secure the housing to an outside surface of the patient's skin. Multiple locations on the patient's skin may then be accessed for deployment of one or more delivery cannulas via a plurality of cannula ports for delivery of fluid and from the fluid source to multiple subcutaneous locations below the patient's skin and timely movement of cannula access in the patient's skin without the need for relocating the housing.
    Type: Application
    Filed: July 24, 2019
    Publication date: January 30, 2020
    Inventors: Paul M. DiPerna, Marc Goldman
  • Publication number: 20200030530
    Abstract: An elastic physiological patch includes a patch assembly and an implant assembly. The patch assembly includes an electronic device, and a soft patch body defining a chamber for receiving the electronic device. The implant assembly is mountable to the electronic device and includes an implant which is capable of being driven to partially pass through the patch body and which is adapted to be implanted in the skin of a subject. The implant and the patch body cooperatively seal the chamber.
    Type: Application
    Filed: July 23, 2019
    Publication date: January 30, 2020
    Applicant: BIONIME CORPORATION
    Inventors: Chun-Mu HUANG, Chieh-Hsing CHEN, Jia-Nan SHEN, Kuan-Lin CHANG
  • Publication number: 20200030531
    Abstract: A computerized electro-mechanical drug delivery device configured to deliver at least one dose of two or more medicaments. The device comprises a control unit. An electro-mechanical drive unit is operably coupled to the control unit and a primary reservoir for a first medicament and a secondary reservoir for a fluid agent, e.g. a second medicament. An operator interface is in communication with the control unit. A single dispense assembly is configured for fluid communication with the primary and the secondary reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile, the control unit is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament. Further, a dispense interface for use with a drug delivery device is disclosed.
    Type: Application
    Filed: October 10, 2019
    Publication date: January 30, 2020
    Inventors: Shane Alistair Day, Daniel Thomas De Sausmarez Lintell, Steven Wimpenny, Christopher Jones, Aidan Michael O'Hare, Barry Yates, Robert Frederick Veasey, Christopher James Smith, Malcolm Boyd, David Martin Leak, Carmen Patricia Keating, David Sanders, Elizabeth Anne Marshall
  • Publication number: 20200030532
    Abstract: A computerized electro-mechanical drug delivery device configured to deliver at least one dose of two or more medicaments. The device comprises a control unit. An electro-mechanical drive unit is operably coupled to the control unit and a primary reservoir for a first medicament and a secondary reservoir for a fluid agent, e.g. a second medicament. An operator interface is in communication with the control unit. A single dispense assembly is configured for fluid communication with the primary and the secondary reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile, the control unit is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament. Further, a dispense interface for use with a drug delivery device is disclosed.
    Type: Application
    Filed: October 10, 2019
    Publication date: January 30, 2020
    Inventors: Shane Alistair Day, Daniel Thomas De Sausmarez Lintell, Steven Wimpenny, Christopher Jones, Aidan Michael O'Hare, Barry Yates, Robert Frederick Veasey, Christopher James Smith, Malcolm Boyd, David Martin Leak, Carmen Patricia Keating, David Sanders, Elizabeth Anne Marshall