Abstract: A nasogastric tube securement system. The system can include a base layer and a coupling layer. The base layer can be configured to be adhered to a nose, having a first major surface comprising a skin-contact adhesive and a footprint area of A. The coupling layer can include a first end comprising coupling means configured to be repositionably coupled to the second major surface of the base layer; a second end configured to secure a nasogastric tube, and a middle section connecting the first end and the second end. The first end of the coupling layer can have a footprint area of at least 0.3 A. The middle section can be elongated along a longitudinal direction, and the first end and the second end can each be wider than the middle section in a lateral direction oriented substantially perpendicularly with respect to the longitudinal direction.

Abstract: Medical article securement devices are described. These devices retain a medical article, for example, a catheter hub or other luer access device, in position on a patient's body and reduce or inhibit the article's longitudinal or other movement.

Abstract: The present invention includes a device and a method for reducing the anxiety and/or fear of a patient to an intravenous (IV) attachment, the IV attachment comprising: a figurine that a child, or a person with fear and/or anxiety find as cute, whimsical, appealing, or that reduces their fear and/or anxiety; and an IV ending that connects and closes an end of an IV assembly.

Abstract: A catheter assembly may include a catheter adapter, which may include a proximal end, a distal end, a lumen extending through the proximal end and the distal end, and a side port. The catheter assembly may include an extension set, which may include a first extension tube that may extend from the side port. The extension set may include a first connector, which may be coupled to a proximal end of the first extension tube. The first connector may include a first port and a second port. The extension set may also include a second extension tube. A distal end of the second extension tube may be coupled to the first port. The second extension tube may be longer than the first extension tube. The extension set may include a second connector, which may be coupled to the proximal end of the second extension tube.

Abstract: An attachment for a catheter assembly may include a platform, which may include an upper surface and a bottom surface. The bottom surface may be configured to contact skin of a patient. At least a portion of the upper surface may be configured to support the catheter assembly. The upper surface may support the catheter assembly at an angle with respect to skin of the patient that is approximately equal to an insertion angle of a catheter of the catheter assembly. The attachment may include snap feature coupled to the upper surface of the platform. The attachment may include a blunt cannula extending distally from the snap feature. The blunt cannula and the portion of the upper surface may provide a generally straight pathway for an instrument inserted distally through the attachment into the catheter assembly.

Abstract: The medical safety device utilizes an active needle retraction assembly and a guidewire retraction assembly which retracts the guidewire at a retraction rate greater than the needle retraction rate to safely manage significant lengths of guidewire. A passive retraction system may be used with the active retraction assembly to rapidly retract the needle and guidewire after initial retraction. The guidewire retraction assembly includes a pulley system to increase forces applied to the device to retract the guidewire and needle retraction assembly retracts the needle. The device encloses the needle and guidewire to protect from contact with contaminated materials.

Abstract: The present application includes a sheath that is suitable for use in a variety of medical procedures. In one or more implementations, the sheath includes a shunt member, and a curvable portion. The curvable portion may be configured in various orientations to facilitate an intervention, such as a hemodialysis intervention, or the like, by an operator. The curvable portion may be configured to bend between a substantially straight configuration and a curved configuration. In implementations, the sheath may be configured to have detachable and/or interchangeable components (e.g., shunt member, curvable portion, etc.).

Abstract: A body cavity irrigation and drainage system and a related method. The body cavity irrigation and drainage system may include two pigtail catheters that are coupled together so that when in a use state the tail portions of the two pigtail catheters curl in opposite directions. The two pigtail catheters may be coupled together so that they are maintained in a fixed relative orientation. The system may also include a sheath having a cavity within which both of the two pigtail catheters are positioned during an insertion process. The sheath may be a peel-away type sheath such that the sheath can be torn and removed from the body cavity while the two pigtail catheters remain in the body cavity.

Abstract: An optical guidewire system employs an optical guidewire (10), an optical guidewire controller (12), a guide interface (13) and an optical connector (15). The optical guidewire (10) is for advancing a catheter (20) to a target region relative to a distal end of the optical guidewire (10), wherein the optical guidewire (10) includes one or more guidewire fiber cores (11) for generating an encoded optical signal (16) indicative of a shape of the optical guidewire (10). The optical guidewire controller (12) is responsive to the encoded optical signal (16) for reconstructing the shape of the optical guidewire (10). The guidewire interface (13) includes one or more interface fiber core(s) (14) optically coupled to the optical guidewire controller (12). The optical connector (15) facilitates a connection, disconnection and reconnection of the optical guidewire (10) to the guidewire interface (13) that enables a backloading the catheter (20) on the optical guidewire (10).

Abstract: A catheter devices/systems and methods therefrom are described herein for treating acute kidney injury, especially the contrast-induced acute kidney injury wherein the devices prevent the contrast dyes from entering into kidney and/or facilitate blood flow of kidney by said catheter system.

Abstract: An introducer may include a layered tubular member having an inner liner including at least one folded portion extending along a distal region of the inner liner in a delivery configuration; a reinforcing member disposed over at least a portion of the inner liner, the reinforcing member including a plurality of longitudinal spines defining a plurality of openings disposed between adjacent longitudinal spines, wherein each folded portion is circumferentially overlapped by one of the plurality of openings; and an outer sheath disposed over the reinforcing member, wherein the outer sheath includes at least one perforation circumferentially overlapping each folded portion; and a tip member fixedly attached to a tapered distal region of the layered tubular member. The inner liner may extend to a distal end of the layered tubular member. At least a portion of each folded portion may terminate proximal of the distal end of the layered tubular member.

Abstract: A discharger includes a dispensing element and a housing. The housing has a static piston connected to the dispensing element at least in a fluid conducting manner. The static piston has a piercing tip and is arranged within the housing.

Abstract: A liquid dispensing applicator may include a liquid source for housing a liquid, the liquid source having a first end and a second end, the second end being closed; a swab member for dispensing said liquid, the swab member being disposed at the first end; and at least one capillary member being in fluid communication with the liquid source, the capillary tube directing fluid out from the liquid source onto an exterior of the swab member upon application of pressure to the liquid source. A liquid dispensing applicator may also include an applicator tip fluidically connected to the liquid source including a frangible juncture and a tongue member coupled to the frangible junction, application of force to the tongue member causing the frangible junction to fracture while remaining attached to the tongue member, resulting in at least one aperture to form through which liquid from the liquid source is dischargeable.

Abstract: A method for manufacturing a fine hollow protruding tool (1) having an opening portion (3h) of the present invention includes: a protrusion forming step of contacting a protrusion-forming projecting mold part (11A) including a heating means with first face (2D) of a base material sheet (2A), and inserting the protrusion-forming projecting mold part (11A) while softening, by heat, a contact point (TP) to form a fine hollow protrusion (3) which projects from the second face (2U) and which does not penetrate the projecting base material sheet (2A); a cooling step of cooling of cooling the fine hollow protrusion (3) in a state where the protrusion-forming projecting mold part (11A) is inserted therein; a release step of, after the cooling step, withdrawing the protrusion-forming projecting mold part (11A) to form a fine hollow protrusion (3) having a hollow interior; and an opening portion forming step of forming an opening portion (3h) which penetrates an interior portion of the fine hollow protrusion (3), at a

Abstract: Methods and apparatus for supporting microneedles are provided. The apparatus includes a plurality of pedestals extending away from a base and transversely spaced-apart from each other by inter-pedestal volumes. Each of the pedestals has a transversely extending contact surface. For each of the pedestals, one or more microneedles extend from the contact surface of the pedestal.

Abstract: Various embodiments of a device, a kit and method for delivering a drug depot are disclosed. The device comprises a housing including a lower body, an upper body, a ring member, and a drug cartridge. The lower body defines a lower body channel. The upper body defines an upper body channel. The drug cartridge defines a depot channel. The ring member is disposed extending upward from an annular step surface of the lower body toward a housing upper end. The ring member includes indicia indicating a characteristic of one or more drug depots in the drug cartridge. A plunger has a push rod for expelling the drug depot through the cannula to a site in the patient. A kit comprises the above components. A method includes assembling the components including selecting a ring member having indicia corresponding to one or more drug depots in the drug cartridge.

Abstract: Disclosed herein in is a medical tube comprising a hydrogenated styrenic block copolymer having a formula A-B-A, (A-B-A)nX or (A-B)nX is disclosed, where n is an integer from 2 to 30, and X is residue of a coupling agent. Prior to hydrogenation, each A block is a monoalkenyl arene homopolymer block having a true peak molecular weight of 5 kg/mol to 15 kg/mol. Each B block is a controlled distribution copolymer block having a true peak molecular weight of 30 kg/mol to 200 kg/mol. The hydrogenated styrenic block copolymer has a midblock poly(monoalkenyl arene) content of 35 wt. % to 50 wt. % based on the total weight of the midblock, and physical properties that makes it useful for producing medical tubes having kink resistance.

Abstract: A female connector (1) includes a female member (10). An inner circumferential face of the female member (1) includes a first region (11), and a second region (12) that is arranged on a tip side of the first region (11). The first region (11) is composed of a female tapered face whose inner diameter increases toward the tip of the female member. The second region (12) is composed of a cylindrical face whose inner diameter is constant along a central axis direction.

Abstract: A catheter adapter may include a distal end, a proximal end, a lumen extending between the distal end and the proximal end, and a side port. A central axis of a fluid path extending through the side port may be disposed at an angle with respect to a longitudinal axis of the catheter adapter. The angle may be less than 45°. Additionally or alternatively to the angle being less than 45°, the catheter adapter may include a wedge and/or an insert configured to facilitate instrument delivery to the catheter assembly via the side port.

Abstract: A connector for transferring fluid and method therefor. The connector may have a first port and a second port which may be coupled together at a main channel with a valve element therein controlling fluid flow through the first port. The first port joins the main channel to provide a fluid path around the valve element and through the second port.

Abstract: A catheter priming apparatus may include a barrier forming a reservoir. Fluid may be disposed within the reservoir. A support structure may be disposed within the barrier. The support structure may include an opening extending through the support structure and a connector configured to couple the catheter priming apparatus to a catheter system. A one-way valve may be coupled to the support structure and configured to allow the fluid to flow out of the reservoir through the connector in response to compression of a portion of the barrier aligned with the opening.

Abstract: Damage from autoimmune diseases can be prevented or minimized by positioning a plurality of electrodes in or on a subject's body, and applying an AC voltage between the plurality of electrodes so as to impose an alternating electric field through the tissue that is being attacked by the autoimmune disease and/or draining lymph nodes associated with that tissue. The frequency and field strength of the alternating electric field are selected such that the alternating electric field inhibits proliferation of T cells in the tissue to an extent that reduces damage that is caused by the autoimmune disease.

Abstract: A garment worn by the patient is provided. The garment has a first module electrically connected to a second module. The first module has a first sub-control unit electrically connected to a first electrode and a second electrode placed at a first muscle of the patient and a third electrode and a fourth electrode placed at a second muscle. The sub-control unit is electrically connected to a master unit. The first muscle is stimulated with a first stimulation signal without shortening the first muscle by sending the first stimulation signal to the first electrode placed at the first muscle. The stimulation of the first muscle relaxes the second muscle. A measuring unit (U1) of the master unit determines a first current value flowing from the first electrode through the first muscle to the second electrode and sends the first current value to a central processing unit (CPU).

Abstract: A subcutaneously implantable device includes a housing, a clip attached to a top side of the housing, a first prong with a proximal end attached to the housing and a distal end extending away from the housing, and a first electrode on the first prong. The clip is configured to anchor the device to a muscle, a bone, and/or a tissue. The first prong is configured to contact a heart. The first electrode is configured to contact the heart. Sensing circuitry in the housing that is configured to sense an electrical signal from the heart, and therapeutic circuitry in the housing is in electrical communication with the first electrode and is configured to deliver electrical stimulation to the heart through the first electrode.

Abstract: A relatively compact implantable medical device includes a fixation member formed by a plurality of fingers mounted around a perimeter of a distal end of a housing of the device; each finger is elastically deformable from a relaxed condition to an extended condition, to accommodate delivery of the device to a target implant site, and from the relaxed condition to a compressed condition, to accommodate wedging of the fingers between opposing tissue surfaces at the target implant site, wherein the compressed fingers hold a cardiac pacing electrode of the device in intimate tissue contact for the delivery of pacing stimulation to the site. Each fixation finger is preferably configured to prevent penetration thereof within the tissue when the fingers are compressed and wedged between the opposing tissue surfaces. The pacing electrode may be mounted on a pacing extension, which extends distally from the distal end of the device housing.

Abstract: In one aspect, an apparatus for stimulating and/or monitoring a nerve is described herein. In some embodiments, the apparatus comprises a top substrate layer, a bottom substrate layer in facing opposition to the top substrate layer, and a channel disposed between the top substrate layer and the bottom substrate layer. The apparatus further comprises a plurality of electrodes disposed on one or more interior surfaces of the channel. Additionally, the channel is defined by the top substrate layer, the bottom substrate layer, and a retaining wall extending at least partially between the top substrate layer and the bottom substrate layer. The retaining wall retains the nerve within the channel.

Abstract: Implementations described and claimed herein provide paddle leads for dorsal root ganglia (DRG) stimulation and methods of implanting the same. In one implementation, the paddle lead has a small profile facilitating deployment into a target space in the neuroforamen dorsal to the DRG and below the vertebral lamina. A paddle body of the paddle lead may include a living hinge and/or a contoured profile to further facilitate implantation in the target space. For suture assisted deployment as well as to resist migration of the paddle lead once deployed, the paddle lead may include a suture loop configuration. The paddle lead further includes an electrode array having electrode contacts arranged in a two dimensional configuration pattern to create an electrical field optimized for stimulation of the DRG.

Abstract: A percutaneous lead assembly for an active implantable device, the lead assembly comprising a sheath with a plurality of wires extending from a proximal end to a distal end. The wires being adapted to power the active implantable device; the distal end having at least one electrode fixed thereon. The electrodes being in communication with sensor electronics and wherein at least one electrode is on the outer layer of the lead assembly in which the electrode is used to detect at least one of acceleration and electrical signals of an organ.

Abstract: Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and/or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and/or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

Abstract: Devices, systems and methods are provided for treating migraine headaches and other conditions by non-invasive electrical stimulation of nerves and other tissue. A hand-held device includes a housing with a controller having a signal generator, an electrode for delivering electrical signals, and a conductive surface configured as a return path for the electrical signals. In certain implementations, the electrode is repositionable with respect to the housing. The patient can self-apply the hand-held device by pressing it against areas in need of pain relief. The device may include a pressure-sensitive gating switch to control delivery of the stimulation therapy. In certain embodiments, the electrode is a rollerball electrode. The device may include a chamber for retaining and dispensing conductive gel to the therapy site. In certain approaches, the device includes an electrode support for coupling an electrical stimulation system to the head for hands-free electrical stimulation therapy.

Abstract: Systems and methods are provided for detecting arrhythmias in cardiac activity is provided. The systems and methods include measuring conduction delays between an atria (A) and multiple left ventricular (LV) electrodes to obtain multiple intrinsic A/LV intervals, measuring conduction delays between a right ventricular (RV) and the multiple LV electrodes to obtain multiple intrinsic VV intervals. The systems and methods include calculating a first atrial ventricular (AV) delay based on at least one of the intrinsic A/LV intervals, and calculating a second AV delay based on at least one of the intrinsic VV intervals. The systems and methods include selecting a biventricular (BiV) pacing mode or an LV only pacing mode based on a relation between the first and second AV delays, and delivering a pacing therapy based on the selecting operation.

Abstract: Differential charge-balancing can be used in high-frequency neural stimulation. For example, a neural stimulation apparatus can have first and second electrodes configured to be coupled proximate to a nerve fiber to implement a neural stimulation procedure. A neural stimulation circuit can be electrically coupled to the first and second electrodes. The neural stimulation circuit can apply stimulation currents to the nerve fiber through the first and second electrodes during a first stimulation phase of the neural stimulation procedure. The neural stimulation circuit can also apply a modified stimulation current to the nerve fiber through the first electrode during a second stimulation phase of the neural stimulation procedure. The modified stimulation current can be generated based on a difference between (i) a voltage at the first electrode, and (ii) a reference voltage derived from voltages on the first and second electrodes.

Abstract: A neuromodulation system comprises a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes, a user interface configured for receiving input from a user that selects one of a plurality of different shapes of a modulating signal and/or selects one of a plurality of different electrical pulse parameters of an electrical pulse train, neuromodulation output circuitry configured for outputting an electrical pulse train to the plurality of electrical terminals, and pulse train modulation circuitry configured for modulating the electrical pulse train in accordance with the selected shape of the modulating signal and/or selected electrical pulse parameter of the electrical pulse train.

Abstract: The present invention provides improved methods for positioning of an implantable lead in a patient with an integrated EMG and stimulation clinician programmer. The integrated clinician programmer is coupled to the implantable lead, wherein the implantable lead comprises at least four electrodes, and to at least one EMG sensing electrode minimally invasively positioned on a skin surface or within the patient. The method comprises delivering a test stimulation at a stimulation amplitude level from the integrated clinician programmer to a nerve tissue of the patient with a principal electrode of the implantable lead. Test stimulations are delivered at a same stimulation amplitude level for a same period of time sequentially to each of the four electrodes of the implantable lead.

Abstract: Disclosed herein are implantable medical devices (IMDs) including a receiver and a battery, and methods for use therewith. The receiver includes first and second differential amplifiers, each of which monitors for a predetermined signal within a frequency range and drains power from the battery while enabled, and while not enabled drains substantially no power from the battery. To remove undesirable input offset voltages, each of the differential amplifiers, while enabled, is selectively put into an offset correction phase during which time the predetermined signal is not detectable by the differential amplifier. At any given time at least one of the first and second differential amplifiers is enabled without being in the offset correction phase so that at least one of the differential amplifiers is always monitoring for the predetermined signal. In this manner, the receiver is never blind to signals, including the predetermined signals, sent by another IMD.

Abstract: Systems, devices and methods to facilitate wireless interaction between an implantable therapy delivery device and an external transmitter device are provided. In an example, the systems, devices, and methods discussed herein include or use a garment for receiving and positioning an external transmitter device proximal to an implanted device, and the external transmitter device includes a midfield device configured to provide one or more signals to manipulate evanescent fields outside of tissue to generate a propagating and focused field in the tissue. In an example, the garment includes a receptacle configured to receive and retain the external transmitter device near a tissue interface, and the garment further includes a dielectric portion provided between the receptacle and the tissue interface. In an example, the dielectric portion has a relative permittivity that is approximately the same as the relative permittivity of air.

Abstract: An implantable medical device has a device housing. The device housing has a first device housing shell and a second device housing shell. The device housing surrounds an interior space. The implantable medical device further has an electrical component arranged in the interior, as well as a mounting frame, which is arranged in the interior and surrounds the electrical component. The mounting frame has at least one clamping structure. The at least one clamping structure is configured to exert a force onto the electrical component in order to fix the electrical component in the interior of the device housing.

Abstract: A portable defibrillator according to embodiments of the present invention includes a defibrillator engine configured to receive defibrillator information from defibrillator sensors coupled to a patient and display the defibrillator information; an external device engine configured to receive information from medical device sensors coupled to the patient; a medical device virtual machine configured to display the patient parameter information from the external device engine; and a display screen operating a user interface through which the defibrillator engine displays the defibrillator information and the medical device virtual machine displays the patient parameter information from the external device engine.

Abstract: Disclosed is a transcranial magnetic stimulation treatment apparatus applicable to the technical field of medical devices, comprising a TMS coil, a support, a mechanical arm, a controller, and a positioning device. The positioning device detects the position of a human head and the TMS coil and sends positional information to the controller; the controller controls six driving mechanisms of the mechanical arm to rotate to a corresponding angle. Because the mechanical arm has six degrees of freedom, the TMS coil is capable of stimulating each cerebral region of the brain, and the positioning device is capable of detecting an accurate position of the human head, thereby controlling the mechanical arm to accurately position the TMS coil on the human head, and to reduce manual operation.

Abstract: Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength ?1, to generate a second wavelength ?2 of radiation having a higher energy than the first wavelength ?1.

Abstract: A laser therapeutic apparatus includes a laser and a therapeutic optical fiber. The therapeutic optical fiber is configured for being implanted into a body of a patient during surgery to perform a repair treatment on a spinal cord site to-be-treated by irradiation and then being removed from the body of the patient after the surgery. The therapeutic optical fiber includes N number of laser fibers, N?1 number of optical fiber connection components, an optical fiber guiding structure, and an optical fiber controller; the N number of laser fibers are coupled with one another by the N?1 number of optical fiber connection components to form a cascaded optical fiber structure, an end of the cascaded optical fiber structure is coupled to the optical fiber guiding structure, and another end of the cascaded optical fiber structure is coupled to the optical fiber controller.

Abstract: A method of treatment including: selecting tissue to be exposed to radiation for gradual closure of one or more blood vessel within the tissue to be exposed radiation; selecting radiation levels to promote gradual constriction of the one or more vessel; exposing the tissue to be exposed radiation to selected radiation levels.

Abstract: An example particle therapy system includes: a particle accelerator to output a beam of charged particles; and a scanning system to scan the beam across at least part of an irradiation target. An example scanning system includes: a scanning magnet to move the beam during scanning; and a control system (i) to control the scanning magnet to produce uninterrupted movement of the beam over at least part of a depth-wise layer of the irradiation target so as to deliver doses of charged particles to the irradiation target; and (ii) to determine, in synchronism with delivery of a dose, information identifying the dose actually delivered at different positions along the depth-wise layer.

Abstract: Linear accelerator (“linac”) downtime invariably impacts delivery of patients' scheduled treatments. Transferring a patient's treatment to an available linac is a common practice. Transferring a VMAT plan from a linac equipped with a standard-definition MLC to one equipped with a higher definition MLC is practical and routine in clinics with multiple MLC-equipped linacs. However, the reverse transfer presents a challenge because the high-definition MLC aperture shapes must be adapted for delivery with the lower definition device. An efficient method to adapt VMAT plans originally designed for a high-definition MLC to a standard definition MLC is disclosed herein. The dosimetric results of the present adaptation method are presented for head-and-neck, brain, lung and prostate VMAT plans. The delivery of the adapted plans was verified using standard phantom measurements.

Abstract: The present disclosure is related to systems and methods for calibrating a radiation device. The method includes obtaining a plurality of images acquired at each of at least one source-to-image distance (SID) by the imaging device. The method includes determining, based on the plurality of images, at least one first projection position of a first axis of the collimator on the imaging device and at least one second projection position of a second axis of the radiation beam on the imaging device. The method includes determining, based on the at least one first projection position and the at least one second projection position, at least one offset distance between the first projection position and the second projection position. The method includes determining whether to calibrate the radiation device by comparing the at least one offset distance with a threshold.

Abstract: A high-spatial-resolution ultrasonic neuromodulation method and system are provided. The method includes infusing a biological micro-nano material into the operating object by injection; aggregating the biological micro-nano material in the target region by a micro-nano manipulation method; and conducting ultrasonic neuromodulation on the target region by utilizing the ultrasound transducer and using an acoustic intensity between the first minimum acoustic intensity and the second minimum acoustic intensity. By using the method, an ultrasonic neuromodulation effect is generated only in a micro-nano material aggregation region by using a lower acoustic intensity, thereby reducing the threshold of ultrasonic neuromodulation, and greatly improving the spatial resolution of the ultrasonic neuromodulation.

Abstract: An ultrasound transmitter device for treating a patient is provided. The ultrasound transmitter device includes an imaging probe; an imaging array; and a therapeutic ultrasound device, wherein the imaging probe is configured to guide the therapeutic ultrasound device to the patients treatment site by use of ultrasound imaging with the imaging array, wherein the therapeutic ultrasound device is configured to produce a controlled intensity of ultrasound energy for treating the patients treatment site, and wherein the imaging probe and the therapeutic ultrasound device are configured to work in conjunction with one another to apply therapeutic ultrasound to tissue or bone graft sites in the patient.

Abstract: Methods for diagnosing a pathologic tissue membrane, as well as a focused ultrasound apparatus and methods of treatment are disclosed to perform ureterocele puncture noninvasively using focused ultrasound-generated cavitation or boiling bubbles to controllably erode a hole through the tissue. An example ultrasound apparatus may include (a) a therapy transducer having a treatment surface, wherein the therapy transducer comprises a plurality of electrically isolated sections, (b) at least one concave acoustic lens defining a therapy aperture in the treatment surface of the therapy transducer, (c) an imaging aperture defined by either the treatment surface of the therapy transducer or by the at least one concave acoustic lens and (d) an ultrasound imaging probe axially aligned with a central axis of the therapy aperture.

Abstract: Various embodiments are directed to a method of driving an end effector coupled to an ultrasonic drive system of a surgical instrument. The method comprises generating at least one electrical signal. The at least one electrical signal is monitored against a first set of logic conditions. A first response is triggered when the first set of logic conditions is met. A parameter is determined from the at least one electrical signal.

Abstract: An apparatus for operating on tissue includes a body, a shaft assembly, and an end effector. The shaft assembly extends distally from the body and includes an acoustic waveguide. The waveguide is configured to acoustically couple with an ultrasonic transducer. The end effector includes an ultrasonic blade, a clamp arm, and a clamp pad. The blade is in acoustic communication with the waveguide. The clamp arm is configured to pivot about a first pivot point toward and away from the ultrasonic blade and includes a coupling feature. The clamp pad is selectively attachable to the blade to acoustically isolate the clamp arm from the ultrasonic blade. The coupling feature of the clamp arm is configured to provide a snap fit between the clamp pad and the clamp arm and thereby permit manipulation of the clamp pad for removal of the clamp pad from the clamp arm.