Abstract: A method of tissue repair using a surgical assembly that includes the steps of assembling an implant and a driver, capturing tissue with the implant, installing the implant with the captured tissue in a socket or tunnel, advancing a tapered section of a set screw in the implant, thereby expanding the implant and fixing the implant with the captured tissue in the socket or tunnel, and releasing the driver from engagement with the set screw as the distal end of the set screw reaches the implant's closed end. A surgical assembly that includes an expandable implant having a hole with an entrance at a rear end of the implant and a closed end; a set screw, an implant insertion section, a driver engagement section, and a tapered section, where the implant insertion section is received in the hole of the implant, and a driver that is engaged with the set screw.

Abstract: Apparatuses, systems and methods for providing improved intraocular lenses (IOLs), include features for reducing side effects, such as halos, glare and best focus shifts, in multifocal refractive lenses and extended depth of focus lenses. Exemplary ophthalmic lenses can include a continuous, power progressive aspheric surface based on two or more merged optical zones, the aspheric surface being defined by a single aspheric equation. Continuous power progressive intraocular lenses can mitigate optical side effects that typically result from abrupt optical steps. Aspheric power progressive and aspheric extended depth of focus lenses can be combined with diffractive lens profiles to further enhance visual performance while minimizing dysphotopsia effects. The combination can provide an increased depth of focus that is greater than an individual depth of focus of either the refractive profile or the diffractive profile.

Abstract: A prosthetic mitral valve assembly includes a valve component formed with a radially expandable frame and a valve structure supported inside of the frame. In one embodiment, the prosthetic mitral valve assembly further includes an expandable anchor having an annular base. A plurality of cantilevered fixation members extend from the base of the expandable anchor. The fixation members of the expandable anchor are adapted to rotate relative to a longitudinal axis as the valve component is radially expanded within the base of the expandable anchor. As the fixation members rotate, native mitral valve leaflets are securely captured between the fixation members of the anchor and the valve component.

Abstract: Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit. The valve structures may incorporate one or more conduit sinuses, as well as a gap between the lower margin of the valve leaflets and the interior of the conduit. In addition, the valve structures may include one or more valve sinuses created in a space between the valve leaflets and the conduit inner surface. Computational fluid dynamics and mechanical modeling may be used to design the valve leaflets with optimal characteristics. A heart valve structure may also incorporate a biodegradable component to which cells may adhere The incorporated cells may arise from patient cells migrating to the biodegradable component, or the component may be pre-seeded with cells prior to implantation in a patient.

Abstract: Methods for manufacturing or sewing a prosthetic heart valve and associated systems can include an assistance system that includes an automated fixture that can comprise an articulation arm and a target device holder. The automated fixture can be configured to rotate a target device held by the holder. The assistance system can include a camera system configured to generate an enlarged image of the target device, and a display configured to display the enlarged image. The display can also display information to aid an operator in performing a procedure, for example, instructions, reference images, or a visual indicator to indicate a target position on the target device for performing a step of the procedure.

Abstract: An assembly for treating a native valve in a human heart includes a prosthetic heart valve having an expandable frame and a valvular structure. The assembly also includes a tubular sleeve and a valve catheter disposed within the sleeve. A plurality of metal extension arms are coupled to the valve catheter for holding the prosthetic heart valve. The extension arms are configured to radially expand with the prosthetic heart valve during expansion of the prosthetic heart valve at a treatment site. A plurality of metal rods extend distally from the valve catheter. The rods are axially movable relative to the extension arms. A plurality of release members are provided for releasing the prosthetic heart valve from the extension arms upon movement of the metal rods.

Abstract: A delivery device for a collapsible prosthetic heart valve may include a catheter assembly and an operating handle. The catheter assembly may include an inner shaft around which a compartment is defined, and a distal sheath having proximal and distal segments configured to enclose the compartment. The operating handle may include a first lead screw fixedly coupled to the proximal segment, a second lead screw coupled to the distal segment, a knob rotatable relative to a housing of the operating handle and threadedly engaged with the first lead screw, and a coupling assembly. The coupling assembly may have a first condition in which rotation of the knob in one direction moves the first lead screw but not the second lead screw, and a second condition in which rotation of the knob in the one direction simultaneously moves the first lead screw and the second lead screw.

Abstract: Devices, systems and methods facilitate positioning of a cardiac valve annulus treatment device, thus enhancing treatment of the annulus. Methods generally involve advancing an anchor delivery device through vasculature of the patient to a location in the heart for treating the valve annulus, contacting the anchor delivery device with a length of the valve annulus, delivering a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus, and drawing the anchors together to circumferentially tighten the valve annulus. Devices generally include an elongate catheter having at least one tensioning member and at least one tensioning actuator for deforming a distal portion of the catheter to help it conform to a valve annulus. The catheter device may be used to navigate a subannular space below a mitral valve to facilitate positioning of an anchor delivery device.

Abstract: A method of delivering a prosthetic mitral valve includes delivering a distal anchor from a delivery sheath such that the distal anchor self-expands inside a first heart chamber on a first side of the mitral valve annulus, pulling proximally on the distal anchor such that the distal anchor self-aligns within the mitral valve annulus and the distal anchor rests against tissue of the ventricular heart chamber, and delivering a proximal anchor from the delivery sheath to a second heart chamber on a second side of the mitral valve annulus such that the proximal anchor self-expands and moves towards the distal anchor to rest against tissue of the second heart chamber. The self-expansion of the proximal anchor captures tissue of the mitral valve annulus therebetween.

Abstract: Methods and devices for the treatment of cardiac valve dysfunction through the placement of lines and anchors. The lines and anchors can form artificial chordae between valve leaflets and the ventricular wall or papillary muscles or connect the two valve leaflets together. The methods and devices offer a mechanism for performing this technique with the heart still beating, and allows for the placement of multiple lines with a single device.

Abstract: Medical devices, systems, and methods reduce the distance between two points in tissue, often for treatment of congestive heart failure and often in a minimally invasive manner. An anchor is inserted along an insertion path through a first wall of the heart. An arm of the anchor is deployed and rotationally positioned according to a desired alignment. Application of tension to the anchor may draw the first and second walls of the heart into contact along a desired contour so as to effect a desired change in the geometry of the heart. Additional anchors may be inserted and aligned with the first anchor to close off a portion of a ventricle such that the ventricle is geometrically remodeled and disease progression is reversed, halted, and/or slowed.

Abstract: Apparatus and methods to reduce ventricular volume are disclosed. The device takes the form of a transventricular anchor, which presses a portion of the ventricular wall inward, thereby reducing the available volume of the ventricle. The anchor is deployed using a curved introducer that may be inserted into one ventricle, through the septum and into the opposite ventricle. Barbs or protrusions along the anchor body combined with a mechanical stop and a sealing member hold the device in place once deployed.

Abstract: The present invention includes a fluid interface system for use in medical implants. The fluid interface system of the present invention can include one or more fluid interface channels disposed within an implant. The fluid interface systems can optionally include fluid redirection channels, fluid interface ports and a corresponding instrument to transfer fluid in or out of the fluid interface ports.

Abstract: A method produces a multilayer film for covering a bone defect site. The film comprises at least one substantially completely bioresorbable covering layer, and the at least one covering layer is placed on a thermally deformable and substantially completely bioresorbable molding layer. The at least one covering layer is connected to the molding layer thermally and/or mechanically, preferably in a compressed manner. Mandrel-like protrusions are arranged on the molding layer, and the protrusions are pressed into the at least one covering layer by the placement of the at least one covering layer on the molding layer and/or pushed through the at least one covering layer. Alternatively or in addition to the protrusions, substantially completely bioresorbable connection devices, preferably rivets or pins, are pushed through the molding layer and the at least one covering layer.

Abstract: A joint replacement system for repairing an articular surface of a first bone of a joint includes an anchor portion and an implant portion. The anchor portion includes an anchor to be secured to the bone, and an anchor fixation head including a bone-facing surface (BFS) extending radially outward from the anchor and an implant facing surface (IFS) extending from a periphery of the BFS. The implant portion is formed from a material (e.g., CoCr) more dense than the material of the anchor portion (e.g., Ti) and includes a fixation cavity to receive at least a portion of the anchor fixation head (AFH), the fixation cavity includes an anchor facing surface (AFS) configured to form a frictional connection with the IFS, and a load bearing surface having a contour for articulating against a cooperating articulating surface of a second bone of the joint.

Abstract: A system for repairing a defect on an articular surface of a patient's trochlear region, the system comprising a guide block comprising a body having an exterior surface configured to engage with the saddle portion and ridge portions of the patient's trochlear region, a protrusion extending generally from the body and configured to be received in a first bore formed in the articular surface along a reference axis, and a first cavity extending through the body configured to establish a first working axis displaced from the reference axis, wherein the exterior surface of the body and the protrusion are configured to secure the location of the guide block about the patient's trochlear region.

Abstract: The present disclosure relates to a three-dimensionally (3D) printed tissue engineering scaffold for tissue regeneration and a method for manufacturing the 3D printed tissue engineering scaffold. The 3D printed tissue engineering scaffold may be fabricated at least in part from a composite material having an insoluble component and soluble component. The three-dimensional tissue scaffolds of the disclosure may be fabricated via a rapid prototyping machine. In some instances, the three-dimensional shape of the fabricated tissue engineering scaffold may correspond to a three-dimensional shape of a tissue defect of a patient.

Abstract: Knee prosthesis includes a femoral component adapted to fit on a distal end of the femur and a tibial insert component. The femoral component includes a measured anterior/posterior dimension defined by the posterior condyle surface and the interior surface of the anterior flange and a distal peg provided on a distal bone facing surface of each of the lateral and medial condylar structures, wherein the distal pegs are positioned at a midpoint of the measured anterior/posterior dimension. The implant system provides two distinct sizing segments and the tibial insert has a medial tibial aspect ratio of 0.74 and a lateral tibial aspect ratio of 0.65 to 0.68 for all sizes.

Abstract: An implant resection system for preparing an implant site to replace a defect in an articular surface of a first bone includes a guide configured to be coupled generally perpendicular to the first bone proximate to the defect. The guide includes a body portion defining a plurality of excision passageways. The excision passageways each define a generally cylindrical core pathway configured to extend generally perpendicular to the first bone which partially overlaps with an adjacent generally cylindrical core pathway. A projection associated with each of the plurality of the generally cylindrical core pathways defines a truncated cylindrical excision site extending through a portion of the articular surface. Each truncated cylindrical excision site partially overlaps with at least one adjacent truncated cylindrical excision site.

Abstract: The orthopedic implant locking system may include an eccentric tibial stem having an engagement rod selectively threadingly engageable with a tibial baseplate, a lock housing securable in rotatable and substantial vertical constrained relation relative to the tibial stem, and an extension lock selectively threadingly engageable with the lock housing and including an inner passage keyed to selectively slidably engage the engagement rod in flush engagement therewith. The extension lock may extend or contract in response to rotational movement of the lock housing simultaneously while the extension lock remains in substantial non-rotatable relation relative to the tibial stem.

Abstract: A total joint replacement system comprising a first and a second implant system. The first implant system includes a first implant having a first load bearing surface based on a first removed portion of an articular surface of a patient's first bone, and a first anchor having a first threaded region configured to be secured into the first bone, wherein the first anchor is configured to be secured to the first implant. The second implant system includes a second implant having a second load bearing surface based on a second removed portion of an articular surface of a patient's second bone, and a second anchor having a second threaded region configured to be secured into the second bone, wherein the second anchor is configured to be secured to the second implant.

Abstract: A prosthetic glenoid component (10) comprising a concave external bearing surface (12), a glenoid-contacting surface (14) opposite to the bearing surface, and a plurality of fixation elements (16) protruding from said glenoid-contacting surface (14) oppositely to said bearing surface (12) for location into a peripheral portion (104b) of a glenoid cavity (104) to secure the component to the scapula (102), wherein a central portion (15) of the glenoid-contacting surface (14) is free of fixation elements so as to preserve the integrity of the glenoid vault.

Abstract: Various embodiments comprise an expansible intervertebral implant intended to be implanted in a space between two adjacent vertebrae to at least partly supplant an intervertebral disc, said implant being able to expand along three substantially mutually orthogonal axes so as to comply with the lordosis of the patient while still having increased stability and reliability.

Abstract: Spinal implants that are configured for a minimally invasive approach to a patient's intervertebral disc space, optimized to avoid blood vessels and nervous tissue, maximizing endplate coverage and promoting sagittal balance, are provided. Insertion and fixation can be accomplished through a narrow access window, thereby allowing better access to more spinal levels while being less invasive than other approaches. The spinal implants may facilitate fusion, and include visualization features to assist in the implantation and verify proper placement and vary segmental angle of lordosis. Methods of implanting the spinal implants to treat a patient's spine are also disclosed.

Abstract: An interbody fusion cage having upper and lower canals for receiving the heads of bone screws that have been pre-installed in opposing vertebral body endplates. The proximal wall of the cage preferably has a vertical slot that communicates with each canal and is adapted to allow access by a screwdriver and tightening of the screws.

Abstract: A spinal implant has a first member defining a longitudinal axis. A second member includes an axial cavity configured for disposal of the first member. A third member is rotatable relative to the first member and defines a transverse cavity. A locking element is disposable in the transverse cavity and engageable with the first member to fix the third member relative to the first member. Systems and methods of use are disclosed.

Abstract: An interbody implant includes an implant body extending between an anterior surface and a posterior surface. The implant body includes a first vertebral engaging surface and a second vertebral engaging surface. At least one of the vertebral engaging surfaces defines a cavity configured for disposal of bone growth detectable via medical imaging. Systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: An implant for therapeutically separating bones of a joint has two endplates each having an opening through the endplate, and at least one ramped surface on a side opposite a bone engaging side. A frame is slideably connected to the endplates to enable the endplates to move relative to each other at an angle with respect to the longitudinal axis of the implant, in sliding connection with the frame. An actuator screw is rotatably connected to the frame. A carriage forms an open area aligned with the openings in the endplates. The openings in the endplates pass through the carriage to form an unimpeded passage from bone to bone of the joint. The carriage has ramps which mate with the ramped surfaces of the endplates, wherein when the carriage is moved by rotation of the actuator screw, the endplates move closer or farther apart.

Abstract: A bone graft delivery device, including a dilator sheath arranged to be connected to a first transverse process, the dilator sheath having a first window, a ramp guide removably engageable with the dilator sheath and arranged to be connected to the first transverse process, the ramp guide including a second window and a ramp at least partially connected to the second window, a snake sheath, and a snake arranged to feed the snake sheath through the ramp guide and out of the first and second windows toward a second transverse process, the second transverse process being adjacent to the first transverse process.

Abstract: An orthopaedic impactor includes an elongate member having a first end and a second end; a striking surface connected to the first end; an actuator held by the elongate member; and an impaction assembly held by the elongate member at the second end. The impaction assembly includes a collar that has an opening formed through; an interfacing member that has a threaded end and is split into at least four sections held partially within the opening, the interfacing member having an expansion opening formed to the threaded end that defines a center; and a separator held in alignment with the expansion opening and connected to the actuator. The separator is configured to radially expand the at least four sections away from the center when advanced through the expansion opening by the actuator.

Abstract: A computer-assisted surgery (CAS) system for navigating a surface of an anatomical feature in a coordinate system comprises an apparatus for obtaining points of a surface of an anatomical feature including a base adapted to be secured to the anatomical feature, a spherical joint supported by the base, the spherical joint having a ball member rotatable in at least two rotational degrees of freedom relative to the base and having a center of rotation fixed relative to the base, a distance-measurement device connected to the ball member such that a distance-measurement axis of the distance-measurement device passes through said center of rotation of the ball member. An inertial sensor unit produces signals representative of the orientation of the distance-measurement device.

Abstract: Prosthetic feet that provide for variable and adjustable stiffness are provided. A foot element can include a tongue portion defined or formed by a slot in the foot element that at least partially separates the tongue portion from a remainder of the foot element. The tongue portion can be operably connected to the remainder of the foot member to increase the stiffness of the foot member or operably disconnected from the remainder of the foot member to increase the flexibility of the foot member. The prosthetic foot further includes a mechanism for adjusting whether the tongue portion is operably connected or disconnected from the remainder of the foot member. The mechanism can be selectively actuated to adjust the stiffness of the foot element in dorsiflexion and/or plantarflexion and/or to adjust the degree to which the tongue portion is allowed to flex relative to the remainder of the foot member.

Abstract: A prosthetic or exoskeleton component for a prosthesis or exoskeleton includes a shock-absorbing unit. The shock-absorbing unit contains a damping device that can be controlled by way of a control device. A detection device has a sensor unit for receiving a signal. The detection device is configured to detect uneven ground depending on the acquired signal and to control the damping device in response to the detected uneven ground such that a damping property of the damping device can be adjusted on the basis of a signal of the detection device.

Abstract: A prosthetic system includes a liner adapted to receive a residual limb and including an outer surface defining an outlet, and a socket including an interior surface and including an aperture extending from the interior surface to an external atmosphere. A first sealed volume is defined between a first portion of the outer surface of the liner and a first portion of the interior surface of the socket. A second sealed volume is defined between a second portion of the outer surface of the liner and a second portion of the interior surface of the socket. The first sealed volume is fluidly connected to the outer of the liner, fluidly separated from the second sealed volume by a seal element, and is independent from the second sealed volume throughout use of the system.

Abstract: A luminal stent includes a first tubular body and a second tubular body sleeved on the first tubular body, and at least one end of the second tubular body is sealingly connected to an outer surface of the first tubular body. In a radial support section of the luminal stent, the first tubular body includes at least one first radial support structure arranged in a circumferential direction thereof, and the second tubular body includes at least one second radial support structure arranged in a circumferential direction thereof and a coating film covering the second radial support structure. The second radial support structure has greater radial deformability than the first radial support structure. After implantation, the luminal stent can form a semi-closed gap between the first tubular body and the second tubular body or between the second tubular body and a lumen wall.

Abstract: A hybrid stent includes multiple main cells aligned in a spiral shape and including multiple first link units which are aligned diagonally and spaced at a predetermined distance from each other and multiple second link units which connect adjacent first link units among the multiple first link units and are spaced at a predetermined distance from each other, and one or more open cells adjacent to the multiple main cells in a longitudinal direction and aligned in a spiral shape.

Abstract: An assembly including a deployment device for deploying a stent device into an aorta of a patient is provided. The deployment device includes a rod translatable within an aorta of a patient and a first release wire configured for releasing one or more radially constraining members, wherein the radially constraining members are configured to constrain a diameter of the stent device. The stent device is at least partially permeable and engaged with the deployment device in an initial configuration, wherein a diameter and a length of the stent device in a deployed configuration can be altered by axial translation of the rod and releasing one or more of the radially constraining members by translation of the first release wire.

Abstract: A stent delivery system provided by the present application comprises: a radiopaque tip located at the distal end of the stent delivery system; a beads component comprising at least one expandable part; a funnel component comprising a distal flare structure and a proximal collapsed end, wherein the cross-section of the flare structure gradually increases from its minimum diameter to its maximum diameter along the proximal-to-distal direction; and a core wire located at the proximal end of the stent delivery system; and wherein the distal end of the beads component is fixed on the radiopaque tip and the proximal end of the beads component is fixed on the core wire; wherein the funnel component is coupled with the beads component and the core wire, and is fixed on the core wire through the collapsed end. The present application also provides a flow diversion device and an assembly method of the flow diversion device.

Abstract: An aneurysm bridging device can be placed in the neurovasculature of a patient by advancing the aneurysm bridging device in a small-diameter configuration a delivery catheter to a target region within the neurovasculature and securing the distal region of the aneurysm bridging device to the neurovasculature. While the distal region of the aneurysm bridging device is secured to the neurovasculature, the proximal region of the aneurysm bridging device can be advanced to permit the aneurysm bridging device to expand from the small-diameter configuration and to deform and twist in a central region of the aneurysm bridging device. The proximal region of the aneurysm bridging device can be secured within the neurovasculature to maintain the central region of the aneurysm bridging device in a deformed state.

Abstract: A gastrointestinal device for implanting within a patient's gastrointestinal tract, the device having a central axis and a first expandable portion comprising a hollow tubular braided structure of wire and having a first cylinder extending parallel to the central axis, the first cylinder having a length and a first face; a neck portion extending from the first face of the first expandable portion parallel to the central axis, the neck portion having a first end, a second end, a wall extending between the first end and second end, and a diameter sized to fit within a pylorus; and a second expandable portion comprising a hollow tubular braided structure of wire and having a second cylinder extending parallel to the central axis, the second cylinder having a second face located at the proximal end of the second cylinder and oriented transverse to the central axis.

Abstract: A retrieval device comprising a hook assembly and a capsule assembly. The hook assembly has an attachment feature at a first end. The capsule assembly includes a capsule, a capsule shaft, and a handle connected in series and defining an inner bore. The capsule has a first end defining an opening. The inner bore of the capsule assembly is configured to slidably receive the hook assembly. The handle has a central portion, a first extension portion attached to the capsule shaft, and a second extension portion with a hook assembly lock at a second end. The hook assembly lock is configured to lock the hook assembly to the second extension portion. The second extension portion is configured to pull the hook assembly relative to the capsule shaft, and the first extension portion is configured to push the capsule shaft relative to the hook assembly along the central longitudinal axis.

Abstract: A strapping system for retaining a rigid support member of an orthopedic brace in a desired utilitarian position on a body of a wearer is provided which includes a strap having a first strap end, a second strap end and an intermediate strap point between the strap ends. The strap is operatively configured to follow a strap path having a first connection point, a second connection point and a third connection point sequentially positioned on the support member. The first strap end is attached to the first connection point and the strap extends from the first connection point around the body of the wearer to the second connection point where the intermediate strap point is attached thereto. The strap is redirected at the second connection point in an opposing direction and extends back around the body of the wearer to the third connection point where the second strap end is attached thereto.

Abstract: An orthopedic device has detachable components for treatment stages of an injury or surgical procedure. The orthopedic device is arranged as a protective functional support for regeneration of knee cartilage after surgical repair procedures, and includes a flexion control kit and a wrap-around liner sleeve.

Abstract: The invention relates to a variable orthopaedic back shell having two side shell parts, which can be used as a back orthosis or as a holder for other orthoses, for example shoulder orthoses. The invention also relates to an orthosis which includes a back shell according to the invention, and to the orthopedic use of the back shells.

Abstract: The undergarment having urine-collection system is an external catheter apparatus. The undergarment having urine-collection system is adapted for use with a patient. The undergarment having urine-collection system is an undergarment that is formed with an elastic sheeting. The elastic sheeting is a water impermeable sheeting that collects urine as it is excreted and routes the collected urine to a catheter bag. The undergarment having urine-collection system is worn in the same manner as loin wear would be worn. The undergarment having urine-collection system comprises an undergarment, a tube, and a catheter bag. The tube provides a fluidic connection between the undergarment and the catheter bag.

Abstract: An intraoral device is disclosed. The device includes a curved portion configured to extend along a user's teeth, and first and second back portions connected to the curved portion. In addition, the device includes a plurality of projections extending from each of the first and second back portions, where the projections are positioned such that, when in the user's mouth, the projections are between upper and lower teeth of the user.

Abstract: An intrauterine device includes a central support member, first and second internal flexures and first and second external flexures. The first and second internal flexures each include a first section having a first stiffness, a second section having a second stiffness, and third section having a third stiffness, wherein the second stiffness is more flexible than the first and third stiffness and wherein the first section of each internal flexure is coupled to the central support member. The first and second external flexures are coupled to the central support member and coupled to the third sections of the first and second internal flexures, the first and second external flexures in combination with the first and second internal flexures being configured to extend from a collapsed position parallel to the central support member to a deployed position flexing away from the central support member.

Abstract: Micro-droplet delivery devices and methods are described where the device may comprise a piezoelectric actuator having a piezoelectric chip that is operatively coupled to a drug package under a preloading force. The actuator is configured to generate an acoustic pressure within the drug package to dispense droplets of an agent from an aperture, e.g., to the corneal surface of the eye. The piezoelectric actuator can be coupled or decoupled from the drug package.

Abstract: A contact lens manipulator assembly comprising a main manipulator body (7) arranged to support a lens applicator (2) in one end and a pincer (3) in an opposite end of the main manipulator body (7) is disclosed. The contact lens manipulator comprises further a contact lens fetcher (1) arranged releasable in a longitudinal bore (6) of the main manipulator body (7).

Abstract: The multiport vitrectomy cutter (10) is an ocular surgical tool allowing a surgeon to select between a single cutting port configuration and a multiple cutting port configuration. The multiport vitrectomy cutter includes an internal tube (36) and a rotating external tube (22). The external tube has a plurality of external ports (28, 30, 32) for receiving vitreous of the eye. The internal tube (36) has a closed distal end (38), defining a cutting blade, and is slidably disposed within the external tube (22) so that the cutting blade oscillates across a first one of the external ports (28) to cut tissue. The internal tube (36) has at least one internal port (40, 42), such that selective rotation of the external tube (22) with respect to the internal tube (36) selectively aligns the at least one internal port (40, 42) with a remainder of the external ports (30, 32).