Abstract: An intravascular device delivery system includes a distal end cap to connect an elongated member of the intravascular device delivery system to an intravascular device. The distal end cap includes at least one connection member radially movable relative to the distal end cap that is configured to engage with a complimentary recess in the intravascular device.

Abstract: A prosthetic valve comprises a valve body, comprising a tubular frame and a plurality of leaflets; an upstream support, comprising a second frame; and a flexible sheet that couples the upstream support to the valve body. The prosthetic valve is compressible into a delivery tool such that the prosthetic valve is in a compressed state in which the second frame and the tubular frame are arranged in series within the tool, and the valve body has a compressed body-diameter. The prosthetic valve is deployable from the tool such that the prosthetic valve automatically expands into an expanded state. In the expanded state, the second frame defines an inner perimeter, the sheet extends inwardly from the inner perimeter to the valve body, and the prosthetic valve defines a conduit through the upstream support and the valve body. Other embodiments are also described.

Abstract: The invention relates to a distal anchoring tab for an orthogonally delivered prosthetic mitral valve where the tab is extended using a guide wire to capture native mitral leaflet and/or chordae tissue and withdrawing the guide wire contracts the tab and pins the native tissue against the subannular sidewall of the prosthetic valve.

Abstract: A delivery system includes a delivery catheter with a capsule configured to carry a prosthesis and a steering catheter for steering the delivery catheter. The delivery catheter can be advanced through a patient's vasculature to a target treatment area. The capsule can be opened and the prosthesis can be deployed into the target treatment area. Additionally, a method for delivering a prosthesis to a target treatment area includes advancing a delivery catheter through a patient's vasculature to the target treatment area, steering the delivery catheter toward the target treatment area, opening a capsule on the delivery catheter, and deploying the prosthesis into the target treatment area.

Abstract: A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.

Abstract: A delivery device for a collapsible prosthetic heart valve, the delivery device including an inner shaft, a distal sheath disposed about a portion of the inner shaft and forming a compartment with the inner shaft, the compartment adapted to receive the valve, the inner shaft and the distal sheath being movable relative to one another, and a handle including a frame having a longitudinal axis, a proximal end and a distal end, the handle including a deployment actuator and a hub, the deployment actuator and the hub being independently capable of opening and closing the compartment, a resheathing lock configured to alert a user of a position of the distal sheath and to impede movement of the distal sheath, and an indicator disposed on the frame and capable of showing an extent of deployment of the valve.

Abstract: A bone repair scaffold having two moduli that match those of the cancellous and cortical bone in a patient receiving a bone graft/implant. The bone repair scaffold possesses increased mechanical properties to sustain physiological loading and biologically active capability to facilitate bone fusion. The bone repair scaffold may be 3D-printed, which allows for a variety of scaffold designs and configurations. Pore size, interconnected porosity, shape, and modulus of the bone repair scaffold may be modified for different bone graft applications, whether it is used as filler for bone cancer resections or trauma, or as a fusion device in cases of surgery. Depending on the defect location of the bone shaft, the relative porosity of the scaffold may be modified to account for changes in cortical bone thickness. A method for treating a bone defect using the bone repair scaffold is also disclosed.

Abstract: An implant and method for posterior sacroiliac fusion having a plate for placement across the posterior surface of the sacroiliac joint, a transverse pin to slide through the plate and transverse the joint as well as provide an aperture to receive bone graft, and a sacral screw to be inserted through the plate.

Abstract: The present invention relates to a partial joint replacement (1000), encompassing a shell-like segment (100) with a concave inner contour (3) for the arrangement on at the bone structure of a patient, wherein the segment (100) comprises a lateral section (5) and a medial section (7) along a longitudinal direction (x), and wherein the outer contour (1) of the segment (100) comprise in longitudinal direction (x) at least one inflection point (9).

Abstract: Implant apparatus and methods are directed toward treating conditions involving the knee joint, and the patella specifically, maintain alignment or address misalignment of a patella through a full range of motion of the knee joint Exemplary devices include an elastomeric, Y-shaped device which is secured to the femur and patella on opposite ends thereof by bone anchors. The elastomeric device can be either rotatably or non-rotatably connected to the bone anchors.

Abstract: Methods, systems and apparatuses are disclosed including apparatuses that can be used in a total knee replacement procedure. According to one example, a tibial implant is disclosed. The tibial implant can be configured for attachment to a tibia in a knee arthroplasty and can include a baseplate having a lateral portion and a medial portion oriented relative to an anteroposterior axis and a fixation member. Each of the lateral portion and the medial portion can have a distal surface configured to interface with a resected proximal surface of a tibia. The fixation member can be coupled to and extend both distally and medially from the baseplate such that the fixation member is oriented at an acute angle relative to the distal surface of the medial portion.

Abstract: A reverse shoulder replacement system including a humeral liner defining a split curvature bearing surface that includes a plurality of curvature regions. The plurality of curvature regions are configured to engage a glenosphere of a glenoid implant individually or in combination to provide an improved fit between the glenosphere and the humeral liner.

Abstract: This set comprises glenoid components that each include a body defining, on two of its opposite faces, respectively, a joint surface, intended to cooperate with a humeral head, and a bearing surface bearing against the socket of a shoulder blade. In this set, the glenoid components are provided in several different sizes, respectively defined by the dimensions of the joint surface of their body. At least two glenoid components of which the bearing surfaces respectively have different dimensional geometries are provided so as to allow the surgeon to improve the durability of the mechanical cooperation between the implanted component and the operated socket.

Abstract: Implants, instruments, and methods are presented for fixing adjacent bone portions to promote fusion of the bone portions.

Abstract: A prosthetic system for implantation between upper and lower vertebrae comprises an upper joint component. The upper joint component comprises an upper contact surface and an upper articulation surface. The system further includes a lower joint component. The lower joint component comprises a lower contact surface and a lower articulation surface configured to movably engage the upper articulation surface to form an articulating joint. The articulating joint is adapted for implantation within a disc space between the upper and lower vertebrae, allowing the upper and lower vertebrae to move relative to one another. The system further includes a bridge component extending posteriorly from one of either the upper or lower joint components and from the disc space. The bridge component has a distal end opposite the one of the either upper or lower joint components. The distal end of the bridge component comprises a connection component adapted to receive a fastener.

Abstract: An expansible intervertebral implant is disclosed, various embodiments of which comprise an elongated body along a longitudinal axis comprised between a proximal end and a distal end, a flexible arm mounted in the vicinity of the distal end of the longitudinal body and movable between: a folded-back position with the arm substantially parallel to the axis, and a deployed position with the arm not parallel to the axis and away from the body to expand said implant along an axis, by assuming the general shape of a circular arc, a means for deployment of said flexible arm for deploying the latter from the folded-back position to the deployed position, by the sliding of a proximal portion of said flexible arm with respect to the body inducing an increase in the space occupied by the implant, greater than the space of the implant in the folded-back position.

Abstract: A device and methods for intervertebral spinal fusion of adjacent intervertebral bodies. An intervertebral spacer is positioned within a narrow disc space between adjacent intervertebral bodies of a patient. The spacer is arranged with upper and lower guides. The guides are adapted to simultaneously guide the deployment of upper and lower anchors of an anchoring device into their respective intervertebral bodies. The spacer is also adapted to lock the upper and lower anchors to the spacer in the deployed position.

Abstract: The disclosure claims a lumbar interbody fusion cage for treating lumbar spondylolisthesis via a lateral approach.

Abstract: Implant assemblies, systems, and methods for stabilizing a joint between a superior vertebra and an inferior vertebra may include a plate member coupled to an interbody spacer with at least one fastener that extends superiorly or inferiorly from the implant assembly to anchor within a vertebral body and stabilize the joint. Inserters and methods of insertion may also be included to facilitate fixation of various implant assemblies within the intervertebral space of the joint between the superior vertebra and the inferior vertebra.

Abstract: A stemless humeral component for replacing the humeral head of a patient's humerus includes a support flange having a number of cantilevered legs extending distally away from a bottom surface thereof. Instruments and methods for surgically installing the stemless humeral component are also disclosed.

Abstract: Orthopedic implant sizing instruments, systems, and methods for use during arthroplasty procedures, for example, radial head arthroplasty procedures, are provided. The sizing instruments include at least one sizer head having at least one visualization window or slot provided therethrough for allowing a user to visualize associated surgical structures or surfaces to ensure proper joint reduction. The orthopedic implant sizing instruments, systems, and/or related methods can utilize sizer heads and/or windows having a plurality of different sizes and/or shapes.

Abstract: The invention relates to an orthopedic knee joint, comprising an upper part (2), on which upper connecting means (20) are disposed, a lower part (3) pivotally supported on the upper part (2), connecting means for orthopedic components (4), and a stop ( ) for delimiting an extension movement, wherein the stop (7) is configured displaceably and coupled to an adjusting device (64), which is coupled to a control device (6), which actuates the adjusting device (64) as a function of sensor data and changes the position of the stop (7).

Abstract: Systems and methods for postural control of a multi-function prosthesis are provided. Various embodiments provide for a postural controller that use EMG signals to drive a point in a posture space and outputs continuously varying joint angles for a powered prosthetic hand. The postural controller can include an EMG signal processing unit to receive signals from electrodes for processing (e.g., band pass filtering, rectification, root mean square averaging, dynamic tuning, etc.). The processed EMG signals can then be combined or converted to produce a point in the postural control domain. The PC domain map defines the posture that corresponds to each PC cursor coordinate. This map can have limitless possible postures and limitless possible positions of the postures. The Joint Angle Transform converts the PC cursor coordinate into the joint angle array which is sent to the prosthetic hand thereby creating more natural movements.

Abstract: A stent is formed from a wire having an outer member, a radiopaque member lining at least a portion of the outer member inner surface, and a lumen defined by the outer member inner surface or the radiopaque member inner surface. A substance is disposed in the lumen to be eluted through at least one opening disposed through the outer member to the lumen. The radiopaque member may be substantially continuous along the length of the wire or disposed only along portions of the wire such as crowns. In a method for making the stent, a composite wire including an outer member, a radiopaque intermediate member, and a core member is shaped into a stent pattern and processed to remove the core member and optionally portions of the radiopaque intermediate member, without damaging the outer member.

Abstract: The present invention relates to a catheter system and methods of using such catheter system for the treatment of vascular and non-vascular pathologies. More specifically, the present invention is directed towards a catheter system for the actuation of a temporarily implantable member elastically deformable by hydraulic means.

Abstract: A method of treating a patient suffering from pain in the lower limb or a lower limb musculoskeletal disease is provided. The method includes placement of at least two calibrated, differential disturbances or protuberances under the patient's feet.

Abstract: A thermoplastic cast, which is easy to reuse or implant, and a production method for same, are described. The cast includes a core material to which is attached polycaprolactone while being made in a mesh shape by the mutual crossing over and connecting of threads having a predetermined diameter, with the weaving of a plurality of strands of thin threads; and a structure which is made using a polycaprolactone composite and is formed so as to surround the outer part of the core material by means of insert injection. The patient experiences no discomfort despite the cast being structurally robust, because ventilation properties are improved due to the cast being formed in a mesh shape and because the structure, which is made using the polycaprolactone composite, is formed so as to surround the outer part of the core material by means of insert injection.

Abstract: A device to keep a male glans penis exposed, by extending the glans penis or retracting the foreskin, consisting of a glans penis loop around the glans penis or foreskin and attached to a base strap extending along the underside of the scrotum and penis, which base strap is adjustable to extend the glans penis or retract the foreskin and thereby keeping the glans penis exposed.

Abstract: An obstructive sleep apnea detection device including an optical engagement surface adapted to engage a user's skin; a light source adapted to emit light from the optical engagement surface; a photodetector adapted to detect light at the optical engagement surface and to generate a detected light signal; a position sensor adapted to determine patient sleeping position; a controller adapted to determine and record in memory blood oxygen saturation values computed from the detected light signal and user position information from the position sensor; and a housing supporting the optical engagement surface, the photodetector, the light source, the position sensor, and the controller.

Abstract: An apparatus is provided for breathing assistance that includes a body for positioning within an oral cavity of a user, the body defining at least one first opening for allowing airflow between lips of the user. Two second openings are provided in the oral cavity to allow air flow into and out of a posterior region of the oral cavity and two channels, each channel connecting a respective second opening to the at least one first opening and each channel passing at least one of at least partially along the buccal cavity and at least partially between the teeth to thereby provide an airway for the user. The airway at least partially bypasses the nasal passage and acts to replicate a healthy nasal passage and pharyngeal space.

Abstract: A thermotherapeutic pad includes a sealed envelope having a top layer of plastic and a bottom layer of textured plastic. The top layer of plastic and the bottom layer of textured plastic can be heat-sealed together. The bottom layer of textured plastic has an outer textured surface and is more thermally insulative than the top layer of plastic. A plurality of gel beads and liquid are contained inside the sealed envelope. The bottom layer of the pad can be placed against the skin or clothing to provide thermal therapy. Baffles can be provided inside the sealed envelope to promote even distribution of gel beads.

Abstract: A method of decreasing intraocular pressure (IOP) in an eye of a patient in need thereof includes implanting a first lacrimal implant through a firsts punctum and into a first lacrimal canaliculus of the eye of the patient. The method may further comprise implanting a second lacrimal implant through a second punctum and into a second lacrimal canaliculus of the eye of the patient, and releasing, on a sustained basis a therapeutically effective amount of an intraocular pressure-reducing therapeutic agent.

Abstract: Methods and devices are provided for targeted administration of a drug to a patient's eye. In one embodiment, the method includes inserting a hollow microneedle into the sclera of the eye at an insertion site and infusing a fluid drug formulation through the inserted microneedle and into the suprachoroidal space of the eye, wherein the infused fluid drug formulation flows within the suprachoroidal space away from the insertion site during the infusion. The fluid drug formulation may flow circumferentially toward the retinochoroidal tissue, macula, and optic nerve in the posterior segment of the eye.

Abstract: An ophthalmic laser system includes a laser engine to generate a beam of femtosecond laser pulses, a laser scanner to scan each laser pulse of the beam in three dimensions according to a scan pattern, and a compound lens comprising a glass lens and a birefringent lens, the compound lens arranged to receive the scanned beam and configured to split each laser pulse of the scanned beam into an ordinary pulse and an extraordinary pulse, producing an ordinary beam comprising ordinary pulses and an extraordinary beam comprising extraordinary pulses. A particular ordinary pulse and a particular extraordinary pulse split from a particular laser pulse are spatially separated in depth along an optical axis of the compound lens, by a distance greater than or equal to 5 ?m, and temporally separated by a delay greater than or equal to a pulse duration of the femtosecond laser pulses. An objective is configured to focus the ordinary beam and the extraordinary beam within an ophthalmic target.

Abstract: Goggles include a goggle frame, a goggle strap, and a goggle strap connector. The goggle strap has a direction of strap tension when the goggles are worn by a user. The goggle strap connector includes a female bracket and a male bracket. The female bracket is directly coupled to the goggle frame or the goggle strap, including first and second bracket walls, a channel defined between the bracket walls, projections, and recesses. The male bracket is configured to mateably couple to the female bracket, including a sliding bar and an enlarged bar end. First movement of the goggle strap in the strap tension direction may move at least one of the bar bumps of the enlarged bar end past at least one of the projections to position the at least one of the bar bumps within at least one of the recesses.

Abstract: A shield for protecting the eye of a patient who is undergoing treatment of a facial area, such as the nose-bridge, forehead, temple, or an area immediately surrounding the eye. The shield has an outer shell of a formed semi-flexible or rigid metal foil that extends all the way to the edge of the shield, including an adhesive area of the shield that holds the shield around the eye of the patient. The foil layer is combined with one or more layers of polyester to avoid reflection of the light energy on the user or one or more layers of foam to provide for heat insulation, adhesion and patient comfort. The shield is formed at the contact portion to fit over the orbital area of the patient's eye.

Abstract: A tympanostomy tube delivery device comprises a shaft assembly, a pressure equalization tube, and a trigger assembly. The shaft assembly comprises a cannula and a pusher operable to translate relative to the cannula. The pressure equalization tube is positioned within the shaft assembly. The pusher is operable to drive the pressure equalization tube out of the shaft assembly. The trigger assembly includes a pair of pushbuttons and a linkage. The pushbuttons are secured to the device via living hinges and are selectively pivotable. The linkage is configured to engage the delivery device to thereby selectively prevent actuation of the delivery device. The pivoting of one or both the pushbuttons is configured cause the linkage to collapse so as to disengage the delivery device and thereby actuate the delivery device.

Abstract: A wound treatment system includes a housing that defines an oxygen outlet. An oxygen production subsystem is included in the housing and coupled to the oxygen outlet. A control subsystem is coupled to the oxygen production subsystem and configured to receive pressure information that is indicative of a pressure in a restricted airflow enclosure that is coupled to the oxygen outlet. The control subsystem then uses the pressure information to control power provided to the oxygen production subsystem in order to control an oxygen flow that is created by the oxygen production subsystem and provided through the oxygen outlet to the restricted airflow enclosure.

Abstract: A dressing for an open wound includes a cover layer dimensioned for positioning relative to a wound bed. The cover layer permits an evacuation of the space around the wound bed such that a sub-atmospheric pressure may be established to stimulate healing and facilitate the removal of fluid from the wound. Multiple performance zones in the cover layer allow the wound dressing to remain in position through repeated cycles of evacuation without placing undue strain on the wound bed. An outer peripheral zone may include a high peel-strength adhesive while an intermediate zone may include a shear resistant adhesive. A central zone may be devoid of any coating to maximize moisture transmission through cover layer.

Abstract: A system for treating a tissue site with negative-pressure is described. The system includes a manifold configured to be positioned adjacent to the tissue site and a drape configured to be positioned over the tissue site and the manifold to form a sealed space. The system also includes a negative-pressure source configured to provide negative-pressure to the sealed space. The drape includes a film layer, a layer of a bonding adhesive coupled to the film layer, and a mesh coupled to the layer of the bonding adhesive. The mesh includes a coating of a sealing adhesive and one or more bonding apertures. Methods of manufacturing the drape are also described.

Abstract: A disposable nursing pad has one embodiment with three layers which before use are flat, and in use become cup-shaped. The first layer is an outermost layer, the second layer is a middle layer, and the third layer is an innermost layer. The outermost layer and the innermost layer are disk-shaped. The middle layer has a central body portion and a plurality of arms extending outwardly in a generally spiral pattern. Regions of the first and third layers between the spiral arms can be folded to allow contouring of the liner to the body of a nursing mother.

Abstract: A method for inspecting absorbent articles is provided. The inspection is performed using an inspection algorithm generated with a convolutional neural network having convolutional neural network parameters. The convolutional neural network parameters are generated by a training algorithm. Based on the inspection, characteristics of the absorbent articles, such as defects, can be identified. Absorbent articles having identified characteristics can be rejected, or other actions can be taken.

Abstract: A method for inspecting absorbent articles is provided. The inspection is performed using an inspection algorithm generated with a convolutional neural network having convolutional neural network parameters. The convolutional neural network parameters are generated by a training algorithm. Based on the inspection, characteristics of the absorbent articles, such as defects, can be identified. Absorbent articles having identified characteristics can be rejected, or other actions can be taken.

Abstract: Disclosed is a wearable article comprising a main body and a ring-like elastic belt comprising a front belt and a back belt. At least some of the elastic bodies may be arranged in an array, the array defined as meeting: a) one array is formed by 2-10 elastic bodies; b) each elastic body within one array is disposed in an inner-interval between each elastic body of 2-4 mm; and c) one specific array disposed in an extra-interval between at least one neighboring elastic bodies outside the specific array of greater than the inner-interval. Further, the front belt may comprise at least 5 arrays.

Abstract: A wearable article wherein least some of the elastic bodies may be arranged in at least 2 sets of a concentrated array defined as meeting: a) one concentrated array is formed by 2-4 elastic bodies; b) each elastic body within one concentrated array is disposed in an inner-interval between each elastic body of 2-4 mm; and c) one specific concentrated array disposed in an extra-interval between at least one neighboring elastic body outside the specific concentrated array of less than 8 mm. The entirety of the length of the belt side edge of the front belt may be seamed with a certain length of the belt side edge of the back belt to define a seam length LS. The front and back belts may each divided into 4 zones wherein at least 2 concentrated arrays are disposed on the front proximal tummy zone or the back distal tummy zone.

Abstract: A disposable absorbent garment includes front and rear panels with zones of elastification and non-elastication in the abdomen and rear regions of the garments. The zones of elastification comprise an elastified region, and a non-elastified region or a de-elastified region. The elastified non-elastified or de-elastified regions work in tandem to provide greater contour support and improved fit.

Abstract: An elastic nonwoven laminate that contains an elastic film laminated to one or more nonwoven facings is provided. The nonwoven facing contains a conventional polyolefin and can also contain a polyolefin-based plastomer. The laminate is activated by grooving to decouple the nonwoven facing from the elastic film. To reduce fiber-pull out that can result due to activation by grooving, the laminate can be post-bonded at room or elevated temperatures and a specific range of pressures to compact the fibers of the facing and minimize fiber pull-out/fuzziness while not sacrificing the softness, elasticity, and feel of the laminate.

Abstract: The present invention provides a composite sheet material in which a three-dimensional sheet material and a flat sheet material are firmly joined to each other and which is excellent in ventilation and the like, soft, and good in touch. In the composite sheet material, a three-dimensional sheet material having a large number of protruding portions formed thereon and a flat sheet material not having such protruding portions are layered on each other and joined. The three-dimensional sheet material is joined to the flat sheet material at joining parts apart from protruding portions. A plurality of joining parts are formed around each protruding portion in such a manner as to surround the protruding portion. The area of the joining part is less than 50% of that of a base surrounded by the protruding portions. Some of the joining parts are provided with a through hole penetrating the composite sheet material.

Abstract: An absorbent core for use in an absorbent article is provided and comprises a core wrap enclosing an absorbent material, the absorbent material comprising superabsorbent polymer particles. The superabsorbent polymer particles represent less than 85% by weight based on the total weight of the absorbent material. The core wrap comprises a top side and a bottom side, the absorbent core comprises one or more area(s) substantially free of absorbent material through which the top side of the core wrap is attached to the bottom side of the core wrap, so that when the absorbent material swells the core wrap forms one or more channel(s) along the area(s) substantially free of absorbent material. The superabsorbent polymer particles have a value of Absorption Against Pressure (AAP) of at least 22 g/g according to the Absorption Against Pressure Test Method and a bulk density of at least 0.5 g/ml according to the Bulk Density Test Method.

Abstract: A reconfigurable portable load bearing structure which can be configured into an extended load bearing configuration or a collapsed configuration, comprising of a first, second and third plurality of rail segments that are each rotatably coupled together and a plurality of support segments or pads which are configured to selectively couple and latch into one of a plurality of positions on said first, second and third plurality of rail segments.