Patents Issued in May 7, 2020
  • Publication number: 20200139039
    Abstract: In vivo and ex vivo positionable filtration devices are provided that are functionalized to bind one or more therapeutic agents in blood flowing in a blood vessel.
    Type: Application
    Filed: August 11, 2016
    Publication date: May 7, 2020
    Inventors: Bridget F. Kilbride, Bradford R.H. Thorne, Steven W. Hetts, Vitaliy Lvovich Rayz
  • Publication number: 20200139040
    Abstract: A pressure measuring device 30 installs on a tube 11 for transferring a medium BL so as to measure a pressure of the medium BL inside the tube 11. The pressure measuring device 30 includes a main body portion 31 mountable to the tube 11, polarizing means 34 disposed in the main body portion 31 so that light oscillating in a specific direction is transmitted therethrough, an image acquisition unit 32 disposed in the main body portion 31 so that image information on a pressure receiver that is deformed in response to the received pressure is acquired through the polarizing means 34, and a control unit 100 that converts the image information acquired by the image acquisition unit 32 into pressure information about the pressure.
    Type: Application
    Filed: January 2, 2020
    Publication date: May 7, 2020
    Inventors: Yosuke Itamochi, Kozo Hisamatsu
  • Publication number: 20200139041
    Abstract: A medical device for separating a fluid, in particular for separating platelet-rich plasma from whole blood, includes three containers and at least one corresponding connection line having an intermediate bifurcation. Provided on the connection line are valve means for enabling or preventing a flow of fluid. At least one container includes a hollow container body and a plunger associated in a movable way to the container body. The device also includes a filtering member on the connection line.
    Type: Application
    Filed: December 17, 2019
    Publication date: May 7, 2020
    Applicant: ELTEK S.p.A.
    Inventors: Massimo ZANIN, Marco PIZZI, Laura MAZZUCCO, Marco BERTONI
  • Publication number: 20200139042
    Abstract: An irrigation system having attachable anti-sliding features that prevent movement of the system along a surface. The irrigation system includes a console having a front panel with an inflow pump and an outflow pump. The front panel extends to a front edge of the console and the front edge is connected to a bottom side of the console. The attachable anti-sliding features include one or more feet attached to the bottom side of the console. Each foot has an L-shaped body having a first end and a second end with a first surface and an opposing second surface both extending between the first end and the second end. A protrusion extends from the second end of the body, forming the L-shape. The one or more feet are attached to the bottom side of the console such that the protrusion extends away from the console.
    Type: Application
    Filed: November 4, 2019
    Publication date: May 7, 2020
    Applicant: Conmed Corporation
    Inventors: Mark S. Studenec, James J. Alberti, Eric N. Stubkjaer
  • Publication number: 20200139043
    Abstract: A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engageable with the piston regardless of a rotational orientation of the piston relative to the plunger.
    Type: Application
    Filed: December 16, 2019
    Publication date: May 7, 2020
    Inventors: MICHAEL SWANTNER, RICHARD SEMAN, BARRY TUCKER, ARTHUR UBER, III, KEVIN COWAN, JAMES DEDIG, CHRISTOPHER CAPONE, JAROSLAW WLODARCZYK
  • Publication number: 20200139044
    Abstract: An infusion pump includes: infusion-tube pressing parts configured to press a flexible infusion tube; an infusion-tube receiving surface configured to serve as a receiving surface when the infusion-tube pressing parts press the infusion tube; and a restoration device provided between the infusion-tube pressing parts, the restoration device being configured to move together with the infusion-tube pressing parts along the infusion-tube receiving surface and to press two sides of the infusion tube pressed by the infusion-tube pressing parts, wherein the infusion-tube pressing parts is configured to move sequentially in a longitudinal direction of the infusion tube along the infusion-tube receiving surface to deliver a liquid in the infusion tube in one direction while pressing the infusion tube by sandwiching the infusion tube with the infusion-tube receiving surface.
    Type: Application
    Filed: March 22, 2018
    Publication date: May 7, 2020
    Inventors: Katsuya KONO, Ryoichi AKAI, Shinji AKITOMI
  • Publication number: 20200139045
    Abstract: A fluid infusion system includes an air pump connected to an accumulator tank to produce pressurized air that is stored in the accumulator tank. The system can include one or more fluid bag chambers wherein each fluid bag chamber includes an inflatable bladder positioned inside the fluid bag chamber to apply pressure on the fluid bag supported inside the chamber. The fluid bag can be connected by a tube set to deliver fluid from the fluid bag to a surgical tool at a surgical site. The fluid can, for example, be irrigation fluid or distention fluid. The system can include a controller connected to the pump to control the pump to produce the pressurized air and an adjustable pressure regulator can be connected between the accumulator tank and the inflatable bladder to control the pressure of air delivered to the inflatable bladder and the pressure that the fluid is delivered to the surgical tool.
    Type: Application
    Filed: December 13, 2018
    Publication date: May 7, 2020
    Inventors: Peter Boyle, Keith Isaacson, Seth Traub, Craig Traub
  • Publication number: 20200139046
    Abstract: A reloadable auto injector includes a syringe with a needle movably positioned in a housing between a first position with the needle inside the housing and a second position with the needle protruding outside the housing. A plunger rod advances in the syringe for delivering a dose of medicament. A plunger rod tube having deflectable locking members interacts with a plunger rod stop to lock the plunger rod. A syringe driver moves the syringe from the first position to the second position. The syringe driver advances the plunger rod tube with the plunger rod to the second position. A plunger rod driver advances the plunger rod in the syringe for delivering a dose of medicament upon unlocking each of the deflectable locking members. A reload mechanism retracts the syringe from the second position to the first position and reloads for repeated activation of the syringe driver.
    Type: Application
    Filed: May 16, 2018
    Publication date: May 7, 2020
    Applicant: MERCK PATENT GMBH
    Inventor: Peter Blaabjerg JACOBSEN
  • Publication number: 20200139047
    Abstract: Device for dispensing a substance having: a dispensing element through which the substance can be dispensed, a displaceable protective element for the dispensing element, a drive element that is coupled with the protective element and a feedback element which can generate a signal when or after a predefined quantity or the entire quantity of the substance to be dispensed has been dispensed characterized in that the feedback device is coupled with the drive element.
    Type: Application
    Filed: January 8, 2020
    Publication date: May 7, 2020
    Inventors: Jürg Hirschel, Markus Tschirren
  • Publication number: 20200139048
    Abstract: A portable dual chamber auto-injector configured to store a dry opioid antagonist medicament separately from a liquid component, wherein a user actuated mixing system comprising a movable component to create a fluidic pathway between the first and second chambers and release a portion of energy from a pre-stored energy to drive a displacement mechanism into the first chamber and displace the liquid component into the second chamber and solubilize the opioid antagonist. A needle assembly in fluid communication with the second chamber can be used to transfer the solubilized opioid antagonist.
    Type: Application
    Filed: November 5, 2019
    Publication date: May 7, 2020
    Applicant: Windgap Medical, Inc.
    Inventors: Brent Buchine, Adam R. Standley, Christopher J. Stepanian, Kaliappanadar Nellaiappan, Cole Constantineau, Michel Bruehwiler, Jeffrey Thomas Chagnon, Robert Brik
  • Publication number: 20200139049
    Abstract: A tip cap including a central body extending between a first end and a second end. The first end includes a syringe coupling and the second end can include a projection or pivot. In example embodiments, axial engagement of an end connector of a syringe with the syringe coupling self-connects the tip cap with the end connector of the syringe while rotating about the pivot. According to example embodiments, a flange extends outwardly from the central body to define a width or side-to-side dimension. In example embodiments, the minimum side-to-side dimension is about 1.25 inches.
    Type: Application
    Filed: November 6, 2019
    Publication date: May 7, 2020
    Inventors: Benjamin M. Davis, David A. Doornbos
  • Publication number: 20200139050
    Abstract: The present disclosure relates to a therapeutic agent delivery device with anti-roll features. In one embodiment, a therapeutic agent delivery device may include a tubular body including a first end portion, a second end portion, and a lumen extending between the first end portion and the second portion. An outer surface of the tubular body includes a first opening in communication with the lumen. The outer surface of the tubular body further may include a ledge extending around a periphery of the first opening, and a portion of the ledge closest to the second end portion of the tubular body may be shaped as an arrowhead. The therapeutic agent delivery device also may include a cap configured to engage the second end portion of the tubular body, which may include a curved sidewall extending radially outward. The curved sidewall may include a protrusion.
    Type: Application
    Filed: June 29, 2018
    Publication date: May 7, 2020
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Courtney NICHOLAS, Scott BARTON, Bart E. BURGESS, Alexei GORALTCHOUK
  • Publication number: 20200139051
    Abstract: A resin syringe comprises: a syringe body made of polyolefin, and a printing layer printed on at least a part of an outer surface of the syringe body, wherein the printing layer comprises components including chlorinated polypropylene having a degree of chlorination in a range of 15 to 30%, a colorant, and a filler, wherein a plurality of recessed portions are formed in the outer surface of the syringe body on which the printing layer is printed, and wherein each of the plurality of recessed portions has a depth of 50 nm or more and less than 1 ?m and a width of 50 nm or more and less than 1 ?m and is filled with at least one of the components of the printing layer.
    Type: Application
    Filed: January 3, 2020
    Publication date: May 7, 2020
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Shingo KOYAMA, Kaori ENOMOTO
  • Publication number: 20200139052
    Abstract: A dosing mechanism for an injection device includes a dose-setting element with a first element coupled thereto, which, during dose setting, is rotatable relative to a second element about a main rotation axis in a first direction and, during dose discharge, is fixed in rotation relative to the second element. The first and the second elements are coupled via a sleeve-shaped stop element, which forms a stop abutment. The dosing mechanism includes a stop, and the stop abutment, during the rotation of the first element in the first direction, executes a movement to a stop position where the stop abutment strikes the stop and prevents rotation of the first element relative to the second element in the first direction of rotation. The sleeve-shaped stop element is rotatable about a secondary rotation axis, which is offset parallel to or offset at an angle to the main rotation axis.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Inventors: Susanne Schenker, Ursina Streit, Patrick Hostettler
  • Publication number: 20200139053
    Abstract: A syringe includes a plunger having multiple sections of differing diameters or materials, and a barrel with a cavity into which the plunger is inserted. The barrel includes a first probe and a second probe opposite to one another such that an interior volume of the barrel is radially between the first and second probes. A microcontroller is configured to measure a capacitance between the first and second probes, with the measured capacitance having a first capacitance value when the first section of the plunger shaft is between the first and second probes and a second capacitance value different from the first capacitance value when a second section of the plunger shaft is between the first and second probes. The microcontroller is configured to determine that an injection has been completed when the second capacitance value is measured.
    Type: Application
    Filed: May 25, 2018
    Publication date: May 7, 2020
    Applicant: West Pharmaceutical Services, Inc.
    Inventors: Stacy FAUGHT, Jorge SANTOS
  • Publication number: 20200139054
    Abstract: A safety needle having a rigid outer structure within which there is a cannula holding element of being movably coupled to an injector pen for a drug is provided. The cannula holding element supports a cannula having a first extremity and a second extremity for administration of the drug. A moving protective element associated with the rigid structure, covers the second extremity of the cannula after administration, with provision being made for a deforming member capable of deforming the cannula after administration of the drug so that the second extremity of the cannula remains within the protective element. The deforming member is associated with the protective element and is capable of rotating autonomously with respect thereto after administration of the drug to deform the cannula.
    Type: Application
    Filed: May 29, 2018
    Publication date: May 7, 2020
    Applicant: SOL-MILLENNIUM SWISS R&D CENTER SA
    Inventors: Dario DE ZOLT, Matteo LAGANA
  • Publication number: 20200139055
    Abstract: A hollow needle, for use in medical and other areas where thin hollow needles are used to inject or aspirate fluids and gases, is provided and comprises of a thin, rigid tube body that is open on both ends and throughout the length with one sharp end. A flexible section is provided, either as part of the needle or as an addition at its proximal end allowing the needle to be oriented such that the needle central axis is non-colinear and non parallel to the central axis of the needling system. Depending upon the desired use, needle orientation relative to the central axis can be limited from a conical volume to a planar or multi planar angular orientations. The needling system so configured advantageously allows the user to circumvent an obstacle and or obstacles that otherwise inhibit direct linear access to a point-of-interest by providing a device that can fit around or between obstructions providing optimal direct path towards the desired therapy delivery point.
    Type: Application
    Filed: November 1, 2018
    Publication date: May 7, 2020
    Inventors: David Weksel, Stephen Soloway, Charles S. Brunner
  • Publication number: 20200139056
    Abstract: The invention relates to a novel spring-loaded hypodermic injector device for subcutaneous and intramuscular injection. Specifically, the present invention incorporates a unique spring loaded, non-collinearly aligned double needle transfer/injector head. Also, when the injector is deployed a passive needle cover extends covering the needle and preventing an accidental strike of the needle after the injection is completed.
    Type: Application
    Filed: July 26, 2017
    Publication date: May 7, 2020
    Inventor: Kyle REYNOLDS
  • Publication number: 20200139057
    Abstract: The present invention relates to a dry powder inhaler. The dry powder inhaler includes an inhaler housing, a drug container configured to be provided in the inhaler housing and accommodate the dry powder drug, a drug inlet configured to be disposed above the drug container and through which the dry powder drug is inhaled, and a mesh network configured to be installed on a path of the drug inlet and have a mesh part for collision with the dry powder drug formed therein.
    Type: Application
    Filed: June 29, 2017
    Publication date: May 7, 2020
    Applicant: KOREA UNITED PHARM. INC.
    Inventors: Won Ho KANG, Youn Woong CHOI, Dae Chul HA, Seung Jin YANG, Gweon Hee YU, Kyu Yeol NAM, Kyu Chul JANG
  • Publication number: 20200139058
    Abstract: Containment units, dry powder inhalers, delivery systems, and methods for the same are disclosed. Exemplary devices are configured to have inlets and outlets which are formed with the containment walls of a containment unit. Air jets formed by the configuration of inlet(s) and outlet(s) inside the containment unit create significant turbulence and deaggregate the powder. Delivery system components downstream of the containment unit may integrate the exiting aerosol plume with a low flow nasal cannula air stream for delivery to a subject.
    Type: Application
    Filed: May 31, 2018
    Publication date: May 7, 2020
    Inventors: Philip Worth LONGEST, Michael HINDLE, Dale FARKAS, Susan BOC
  • Publication number: 20200139059
    Abstract: An inhaler for facilitating inhalation of dry powder includes a body defining an interior space and a mouth piece. At least one annular member is positioned within the interior space and is rotatable with respect to the mouth piece. The at least one annular member includes a plurality of compartments. Each compartment defines a cavity configured to hold dry powder. Each compartment includes at least one flap and an opening configured to release the dry powder when the at least one flap is reconfigured from a closed position to an open position. The at least one flap covers the opening and inhibits the dry powder from being released from the cavity in the closed position.
    Type: Application
    Filed: June 4, 2018
    Publication date: May 7, 2020
    Inventors: Jean-Pierre Giraud, Bruce Rabinne, Yutaka Kataoka
  • Publication number: 20200139060
    Abstract: A protective cover for a nasal cannula completely encloses the two prongs of the nasal cannula when properly installed. This protective cover will keep the nasal cannula from contacting potentially unclean surfaces when the nasal cannula is not in use. An optional UV light may be present in the protective cover to provide UV cleaning of the nasal cannula prongs when the cover is closed.
    Type: Application
    Filed: August 14, 2017
    Publication date: May 7, 2020
    Inventor: Charles Andrew Turner
  • Publication number: 20200139061
    Abstract: The present invention provides clinical decision support that can be used with non-portable and portable systems when delivering and/or monitoring delivery of a therapeutic gas comprising nitric oxide to a patient. Further, clinical decision support can be used with non-portable and portable systems during delivery and/or monitoring of delivery of therapeutic gas when nebulized drugs may and/or may not be being delivered to a patient (e.g., when nebulizers are delivered upstream in the inspiratory limb of the breathing circuit, into a breathing gas delivery system, etc.).
    Type: Application
    Filed: November 7, 2019
    Publication date: May 7, 2020
    Inventors: Jaron Acker, Craig R. Tolmie
  • Publication number: 20200139062
    Abstract: The present invention includes cuff pressure monitoring device including a pressure sensor for monitoring pressure inside an airway device cuff; a T-junction coupled to the pressure sensor and capable of being placed in fluid communication with the airway device cuff and in fluid communication with an air source, wherein the T-junction is disposable; one or more electronics units coupled to the pressure sensor with a cable, wherein the cable is disposable; and a human interface coupled to the one or more electronics units, comprising one or more controls, one or more displays, or one or more sound-producing devices.
    Type: Application
    Filed: November 1, 2019
    Publication date: May 7, 2020
    Inventors: Ahmet Can Sabuncu, Ali Beskok, Eric Rosero
  • Publication number: 20200139063
    Abstract: A tracheostoma device holder for holding a tracheostoma device superimposed of a tracheostoma of a person is provided. The tracheostoma device holder may comprise a flexible skirt for attachment over a tracheostoma via a skin adhesive proximal side thereof, said skirt being provided with a through hole. A tubular tracheostoma device fitting may be arranged circumferentially of the through hole, said tubular tracheostoma device fitting extending distally from the distal side of the skirt. The skirt may have at least two sheets, in form of a distal end sheet comprising a skin adhesive hydrogel or hydrocolloid, and a support sheet proximally of said distal end sheet. The support sheet may comprise polyurethane.
    Type: Application
    Filed: January 24, 2017
    Publication date: May 7, 2020
    Inventor: Richard Falkenberg
  • Publication number: 20200139064
    Abstract: A connector device 10 for releasably connecting a bougie 18 or stylet to an endotracheal (intubation) tube (ETT) 12 has a body portion 14 having an opening 16 provided as a longitudinal bore or channel. The connector device can be adjusted to grip the bougie or stylet. The connector device can have passages 40, 41 and a port 42 for supply of gas into or from the ETT. The connector device can include clamping means 30, 32 to clasp the exterior of the ETT to internally grip the bougie or stylet within the ETT. The connector device can grip the bougie or stylet by insertion of the connector device into an open connection end of the ETT. The connector device can form part of the bougie or stylet or be attached thereto, such as by moulding or bonding or other attachment means.
    Type: Application
    Filed: July 7, 2017
    Publication date: May 7, 2020
    Inventor: Christopher Hill
  • Publication number: 20200139065
    Abstract: A vent assembly for use with a respiratory mask of the type used in CPAP treatment includes a porous disk portion that is attached to a biasing member such that the disk portion is maintained in a substantially sealed position against a main vent to minimize airflow through at least one side vent of the vent assembly. Debris build-up on the disk portion can cause the biasing member to deflect to provide an additional path for airflow through the at least one side vent. In another embodiment, the vent assembly can also include an anti-asphyxia feature to provide an airflow path from the environment to the user. An oxygen diverter valve may be disposed between the breathing apparatus flow generator and an oxygen injection port.
    Type: Application
    Filed: January 8, 2020
    Publication date: May 7, 2020
    Inventors: Ian Malcolm SMITH, Muditha Pradeep DANTANARAYANA, Michael Thomas JANIAK
  • Publication number: 20200139066
    Abstract: Systems, devices, and methods for coupling a tracheostomy tube to a source of humidified breathing gas are disclosed. An adaptor includes a housing, a tracheostomy tube connection device, and a baffle. The housing has an interior surface, an exterior surface, and a breathing gas port. The tracheostomy tube connection device is positioned within the housing and includes an input port for receiving a flow of humidified breathing gas from the breathing gas port and an output port for coupling with the tracheostomy tube. The tracheostomy tube connection device has an internal surface defining a breathing gas passage and an external surface spaced from the interior surface of the housing to create a condensation passage. The baffle may be positioned between the breathing gas port and the input port to cause controlled condensation from the flow of humidified breathing gas by disrupting the flow of humidified breathing gas.
    Type: Application
    Filed: August 19, 2019
    Publication date: May 7, 2020
    Inventors: William F. Niland, Felino V. Cortez, JR.
  • Publication number: 20200139067
    Abstract: A system for preventing cross-contamination in single-limb ventilators is described. In one embodiment, the system includes an airflow generator connected in-line to a humidifier, a first check valve and a patient interface by a gas flow circuit. A controller is electrically coupled to the airflow generator, and a cartridge is connected to the gas flow circuit between a first point downstream of the humidifier and a second point upstream of the patient interface. The cartridge includes a bacteria filter and the first check valve. A method for preventing cross-contamination in single-limb ventilators and a method for providing gaseous flow through a single-limb ventilator are also described.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Inventors: Samuel M. CHANG, Nhien M. NGUYEN
  • Publication number: 20200139068
    Abstract: Provided is an exacerbation prediction device equipped with a respiration sensing means of continuously sensing respiration data of a patient, a calculation means of calculating stable respiration data that are respiration data during a condition in which a respiratory rate is lowered and stable for a certain period of time from the sensed continuous respiration data of the patient, and a prediction means of predicting occurrence of an acute exacerbation in the patient in accordance with the stable respiration data calculated during a certain period of time.
    Type: Application
    Filed: May 10, 2018
    Publication date: May 7, 2020
    Applicant: Teijin Pharma Limited
    Inventors: Takayoshi SATO, Sadayoshi MATSUMOTO
  • Publication number: 20200139069
    Abstract: Lightweight, portable oxygen concentrators that operate using an ultra rapid, sub one second, adsorption cycle based on advanced molecular sieve materials are disclosed. The amount of sieve material utilized is a fraction of that used in conventional portable devices. This dramatically reduces the volume, weight, and cost of the device. Innovations in valve configuration, moisture control, case and battery design, and replaceable sieve module are described. Patients with breathing disorders and others requiring medical oxygen are provided with a long lasting, low cost alternative to existing portable oxygen supply devices.
    Type: Application
    Filed: November 8, 2019
    Publication date: May 7, 2020
    Inventors: Stephen Douglas Galbraith, Kenneth J. McGowan, Evonne A. Baldauff, Elise N. Depetris, David K. Walker
  • Publication number: 20200139070
    Abstract: A heat and moisture exchanger (IO) for tracheostomized or laryn-gectomized patients, having a valve plate and a housing, wherein: the valve plate has a radially surrounding lip, and the housing comprises a valve seat which encloses a distal opening of the housing, the valve seat has a groove for receiving the lip, the valve plate is associated with the distal opening of the housing, and the valve plate can be moved into a closed position in which the lip engages in the groove.
    Type: Application
    Filed: December 19, 2018
    Publication date: May 7, 2020
    Inventor: Andreas Fahl
  • Publication number: 20200139071
    Abstract: Various systems generating nitric oxide are disclosed herein. According to one embodiment, the system includes a first gas source providing nitrogen dioxide mixed in air or oxygen, and a second gas source supplying compressed air and/or compressed oxygen. The system also includes a ventilator coupled to the first and second gas sources, wherein the ventilator is resistant to nitrogen dioxide. The ventilator regulates gas flow and allows for the adjustment of nitrogen dioxide concentration in the gas flow. The system further includes one or more conversion devices operably coupled to the ventilator where the conversion devices convert nitrogen dioxide into nitric oxide. A patient interface delivers nitric oxide to the patient and is operably coupled to the conversion devices. The system allows oxygen and nitric oxide levels to be varied independently.
    Type: Application
    Filed: June 18, 2019
    Publication date: May 7, 2020
    Applicant: VERO Biotech LLC
    Inventors: David H. FINE, Bryan JOHNSON, Gregory VASQUEZ
  • Publication number: 20200139072
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Application
    Filed: December 21, 2019
    Publication date: May 7, 2020
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler, Andrew Ferencz
  • Publication number: 20200139073
    Abstract: Various systems generating nitric oxide are disclosed herein. According to one embodiment, the system includes a first gas source providing nitrogen dioxide mixed in air or oxygen, and a second gas source supplying compressed air and/or compressed oxygen. The system also includes a ventilator coupled to the first and second gas sources, wherein the ventilator is resistant to nitrogen dioxide. The ventilator regulates gas flow and allows for the adjustment of nitrogen dioxide concentration in the gas flow. The system further includes one or more conversion devices operably coupled to the ventilator where the conversion devices convert nitrogen dioxide into nitric oxide. A patient interface delivers nitric oxide to the patient and is operably coupled to the conversion devices. The system allows oxygen and nitric oxide levels to be varied independently.
    Type: Application
    Filed: June 20, 2019
    Publication date: May 7, 2020
    Applicant: VERO Biotech LLC
    Inventors: Alfred TECTOR, Priscilla C. PETIT, Kurt A. DASSE, David H. FINE
  • Publication number: 20200139074
    Abstract: Devices, systems, and methods are disclosed which permit ventilation therapy concurrent with humidity and aerosol drug delivery. Exemplary mixer-heaters employ alternating actuation of humidity and drug nebulizers and may use a single constant power setting for the heating section while keeping a controlled outlet temperature over the course of treatment.
    Type: Application
    Filed: May 31, 2018
    Publication date: May 7, 2020
    Inventors: Philip Worth LONGEST, JR., Michael HINDLE, Benjamin SPENCE, Sneha DHAPARE, Wei XIANGYIN
  • Publication number: 20200139075
    Abstract: Secretions that have accumulated at or near an airway of a subject as the subject is being mechanically ventilated are removed by suctioning. Before, during, and/or after the removal of the secretions, steps are taken to mitigated the impact of the suctioning used for secretion removal on the subject. As such, the timing of suction used to remove secretions may be influenced or controlled, ventilation of the subject during suction may be adjusted, ventilation of the subject prior to secretion removal may be adjusted to prepare the lungs of the subject for secretion removal, ventilation of the subject subsequent to suction for secretion removal may be adjusted, and/or other techniques for reducing the impact of suctioning for secretion removal on the subject may be implemented.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Inventors: Smita Garden, Gardner Kimm
  • Publication number: 20200139076
    Abstract: The percussive ventilation breathing head is adapted to be supplied with a flow of pulsatile gas fed to an elongated breathing head body at a proximal end thereof. The breathing head body defines an interior passageway therein. A reciprocating injector shuttle is movably mounted in the breathing head passageway. The shuttle moves distally due to the pulsatile gas, assisted by a diaphragm and a venturi-like jet nozzle which nozzle pulls nebulized aerosol from a depending plenum and a nebulizer attached below the depending plenum. A depending body defines the plenum. The generally cylindrical nebulizer is attached below the depending body. The shuttle is also biased in a proximal direction within the interior passageway and moves proximally due to the bias. The shuttle defines an internal flow passage from a proximal shuttle input port to a distal shuttle output port at the distalmost mouth of the percussive ventilation breathing head body.
    Type: Application
    Filed: April 23, 2019
    Publication date: May 7, 2020
    Inventors: Mark Baillie, Shawn Goughnour, Giles Wilson
  • Publication number: 20200139077
    Abstract: Electronic apparatus that stores user information received from a plurality of sensor that tracks user activities of a user over a specified time period. The electronic apparatus includes circuitry that detects a baseline emotion of the user based on the user information. The circuitry detects a dominant emotion of the user based on a change in an emotional characteristic of the user and the detected baseline emotion. The circuitry further recommends content and an emotional storyboard to the user based on specified emotion associated with the content, the baseline emotion, and the dominant emotion. The recommended content and the emotional storyboard is to induce a change in an emotional type of the dominant emotion from a negative emotional type to a positive emotional type.
    Type: Application
    Filed: November 2, 2018
    Publication date: May 7, 2020
    Inventors: POORNIMA BIRADAR, SANTHOSH RAMEGOWDA, JAISON JOSEPH
  • Publication number: 20200139078
    Abstract: A method and apparatus for stimulating neural activity in the brain of a user of an apparatus with a display screen by causing at least one portion of the display screen to flicker in a controlled manner and utilizing the apparatus to measure an effect on a user exposed to the flicker for a time.
    Type: Application
    Filed: January 29, 2019
    Publication date: May 7, 2020
    Applicant: SYMBOLICS INC.
    Inventor: Russell NOFTSKER
  • Publication number: 20200139079
    Abstract: A system for introducing a delivery apparatus into a patient's vasculature. The system may include a sheath having a lumen and configured to be inserted into the patient's vasculature. An introducer has a channel for receiving a guide wire and is configured to be positioned within the lumen of the sheath. A plug is coupled to the introducer and is configured to move from a first position in which the plug has a first diameter to a second position in which the plug has a second diameter that is greater than the first diameter and greater than the interior diameter of the sheath, the plug being configured to slide within the lumen in a direction from the distal end of the sheath towards the proximal end of the sheath to expand the sheath in the direction radially outward from the lumen.
    Type: Application
    Filed: November 21, 2019
    Publication date: May 7, 2020
    Inventors: Tung T. Le, Sonny Tran
  • Publication number: 20200139080
    Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal member having a proximal end, a distal end, and a proximal diameter. The guide extension catheter may additionally include a collar member attached to an extension portion of the proximal member, where the extension portion may be located at the distal end of the proximal member. The extension portion may allow a delivery device to be inserted through the guide extension catheter to extend along a surface of the extension portion and align with a lumen of a distal sheath of the guide extension catheter.
    Type: Application
    Filed: December 20, 2019
    Publication date: May 7, 2020
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: JEFFREY STEVEN FULLER, SOO-YOUNG YOON, LOUIS WARNER STEFANICH, JOHN E. USCHOLD
  • Publication number: 20200139081
    Abstract: An introducing stylet is configured for insertion into an endotracheal tube (ETT) and includes an elongated rod having a distal end and a proximal end, and a positioning feature formed on the rod and configured to engage the ETT to prevent both longitudinal and lateral movement of the introducing stylet relative to the ETT. A portion of the distal end of the rod that extends longitudinally outwardly of the ETT and defines a leading end.
    Type: Application
    Filed: November 1, 2019
    Publication date: May 7, 2020
    Inventor: Glenn P. Gardner
  • Publication number: 20200139082
    Abstract: A method is provided for making a fiber wire having a fiber bundle core and a polymer jacket. The method includes rotating a spool of fiber bundle about a first rotational axis to progressively unwind the fiber bundle from the spool. The fiber bundle includes a plurality of continuous synthetic fiber filaments. While the spool is rotated about the first rotational axis, the spool is simultaneously rotated about a second rotational axis to thereby twist the unwound fiber bundle about its longitudinal axis. The method further includes coating the twisted fiber bundle with a molten polymer, and permitting the molten polymer to cool to define a flexible outer jacket that encapsulates the twisted fiber bundle.
    Type: Application
    Filed: October 2, 2019
    Publication date: May 7, 2020
    Inventors: George L. Matlock, John H. Thinnes, JR.
  • Publication number: 20200139083
    Abstract: The present disclosure provides a medical device comprising a deflecting assembly configured to assist in deflecting a distal portion of a catheter shaft. The deflecting assembly may include a first rotatable member having a first diameter and a first pull wire coupled thereto and a second rotatable member having a second diameter smaller than the first diameter and a second pull wire coupled thereto, wherein the second rotatable member is coupled to the first rotatable member such that a center point of the second rotatable member is offset from a center point of the first rotatable member. The first and second rotatable members are configured such that rotation of the first rotatable member via the first pull wire causes rotation of the second rotatable member and second pull wire, thus resulting in deflection of a distal portion of the medical device.
    Type: Application
    Filed: November 12, 2019
    Publication date: May 7, 2020
    Inventor: Russell David Terwey
  • Publication number: 20200139084
    Abstract: A medical device includes at least one ionic electroactive polymer actuator, the actuator including at least one polymer electrolyte member defining at least a surface and a plurality of electrodes disposed about the surface of the at least one polymer electrolyte member, an elongate, flexible portion defining a proximal end and a distal end secured adjacent to the ionic electroactive polymer actuator and the elongate, flexible portion further comprising a core and a sleeve surrounding the core and a plurality of electrically-conductive wires, each having a proximal end and a distal end coupled to at least one of the plurality of electrodes, wherein the at least one polymer electrolyte member deforms asymmetrically in response to the application of an electrical potential supplied through at least one of the plurality of electrically-conductive wires to at least one of the plurality of electrodes.
    Type: Application
    Filed: July 27, 2018
    Publication date: May 7, 2020
    Inventors: Daniel H. KIM, Dong Suk SHIN, Viljar PALMRE, Younghee SHIM
  • Publication number: 20200139085
    Abstract: An insertion assembly and method of manufacturing an insertion assembly. The method includes forming a catheter assembly including a catheter hub and a catheter, inserting a needle into the catheter assembly such that a distal tip of the needle extends distal of a distal end of the catheter, and permanently adhering an interface pad to the catheter hub. The interface pad can include a foam material including a haemostatic agent. The haemostatic agent can include microdispersed oxidized cellulose. The foam material can further include an antimicrobial agent such as chlorhexidine gluconate.
    Type: Application
    Filed: January 3, 2020
    Publication date: May 7, 2020
    Inventors: Glade H. Howell, Anthony S. Elangovan, Matthew W. Bown, Bradley J. VanderStek, Lindsey E. Corum, James D. Beal
  • Publication number: 20200139086
    Abstract: A hand-held device is provided for precisely positioning a needle tip at a desired target position into a non-homogeneous material, including a blood vessel. The hand-held device includes a casing hand-held by an operator, a shaft extending along a longitudinal axis and carrying the needle, the shaft mounted in the casing and coupled to the casing to move as a single piece therewith along the longitudinal axis. The hand-held device further includes a sensor unit to provide signals indicative of a physical characteristic of the material wherein the needle tip has to be inserted, and a control unit configured to determine, based on the signals received from the sensor unit, whether the needle tip has reached the target position and to operate a decoupling unit to decouple the shaft and the needle from the casing or to operate an actuating unit to actively move the shaft relative to the casing.
    Type: Application
    Filed: May 28, 2018
    Publication date: May 7, 2020
    Inventors: Leonardo SERRA DE MATTOS, Zhuoqi CHENG, Brian L. DAVIES, Darwin Gordon CALDWELL
  • Publication number: 20200139087
    Abstract: A catheter assembly includes a flexible catheter (22), a needle (12) having a sharp distal tip, the needle (12) disposed in the flexible catheter (22) and moving from a first position that exposes the needle (12) to a second position, an outer member (26) that is configured to engage and disengage a catheter hub (14), an inner member (28) disposed in the outer member (26), and a needle protection (30) member disposed in the inner member (28), the needle protection member (30) enclosing at least a portion of the needle (12) when the needle (12) is in the second position.
    Type: Application
    Filed: January 7, 2020
    Publication date: May 7, 2020
    Applicant: Becton, Dickinson and Company
    Inventors: Weston Harding, John Stokes, Aaron Wang
  • Publication number: 20200139088
    Abstract: A fluid administration medical apparatus (110) comprising: a catheter tube (114); a hub (212) having a distal section (234) and a proximal section (36), wherein the distal section (234) is joined to the catheter tube (114) and the proximal section (136) defines a housing (124); one or more ports (158) connected to the hub (212) by a fluid passage (262) through a passageway (272); a needle (220) extending through the hub (212) and the catheter tube (114) and defining an axial direction (X), wherein the needle (220) has opposite proximal and distal ends (22, 24), the distal end (122) forming a needle tip (130); a needle hub (116) attached to the proximal end (124) of the needle (220); a needle guard (226) slidably arranged on the needle (20), wherein the needle guard (226) is movably retained in the housing (248) of the hub (212) when the needle (220) extends through the hub (212) and the catheter tube (114), wherein the needle guard (226) is removable from the hub (212) once the needle tip (130) is received in
    Type: Application
    Filed: March 23, 2018
    Publication date: May 7, 2020
    Inventor: Rishi Baid