Patents Issued in June 18, 2020
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Publication number: 20200188654Abstract: The disclosure relates to a reduced Larsen Effect electrode. Specifically, the disclosure relates to an electrode with an insulation-coated electrode wire coaxially surrounded over a substantial portion thereof, by predetermined assembly of alternating rigid and isolating layers.Type: ApplicationFiled: February 24, 2020Publication date: June 18, 2020Applicant: Alpha Omega Neuro Technologies Ltd.Inventor: John RIZIK
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Publication number: 20200188655Abstract: Electrodes comprising an electrode coated with a coating, the coating comprising a non-fibrotic material, wherein the non-fibrotic material comprises electrically conductive particles dispersed therein, are provided. The non-fibrotic material may comprise hydrogel lacking cell adhesion moieties. The hydrogel may comprise poly(ethylene) glycol. The electrically conductive particles may comprise gold. Such electrodes may provide electrical stimulation to tissues, while eliminating or reducing fibrosis of tissue coming into contact with the electrodes. Such electrodes may accomplish these ends without the use of drugs. Such electrodes may be useful in applications in which electrical stimulation of tissues is used, such as in cardiac pacemakers, neural stimulators, and muscle stimulators. Methods of making and of evaluating such electrodes are provided.Type: ApplicationFiled: May 8, 2018Publication date: June 18, 2020Inventors: Mehdi Nikkhah, Mark Allen
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Publication number: 20200188656Abstract: A degradable cardiac pacing current-providing wire, comprising: conductive core; insulating film ,covering said conductive core, wherein said conductive core is made of magnesium alloy, the weight percentage of said magnesium alloy is: zinc 4.5-5.5%, manganese 0.8-1.2%, calcium 0.8-1.2%, and the remainder is magnesium, said insulating film is made of either or at least two copolymers of Polylactic acid (PLA), Polyglycolic acid (PGA), Polycaprolactone (PCL), Polydioxanone (PDS) and Polyhydroxyalkanoate (PHA). A cardiac pacing current-providing unit, for use in providing pacing current to the heart of the patient, comprising: wire; suture needle and connecting electrode which is connected to the cardiac pacemaker, there is no wire residue in the body after degradation, and no metal artifacts will occur, which makes the patients free from the need for re-operation, and reduces the mental, physical and economic burden caused by the operation, has a strong clinical application value.Type: ApplicationFiled: December 20, 2016Publication date: June 18, 2020Inventors: Shuping YU, Hao ZHANG
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Publication number: 20200188657Abstract: A system for stimulating tissue generally comprises a resorbable implant. The resorbable implant includes a substrate, at least one contact, and a transceiver, wherein the substrate, the at least one contact, and the transceiver are resorbable. The system also includes a controller configured to communicate with the transceiver of the resorbable implant and a power supply connected to the controller. The controller delivers power to the resorbable implant from the power supply. The resorbable implant delivers electrical stimulation to tissue when the resorbable implant receives power.Type: ApplicationFiled: April 25, 2018Publication date: June 18, 2020Inventors: Wilson Z. Ray, Matthew R. MacEwan, Zohny S. Zohny, John A. Rogers
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Publication number: 20200188658Abstract: A method for positioning an intravascular catheter may include inserting the intravascular catheter into a venous system of a patient, wherein the catheter includes a plurality of electrodes, and multiple electrodes of the plurality of electrodes are configured to emit electrical signals; positioning a distal portion of the catheter in a first position; using one or more electrodes of the plurality of electrodes to acquire an ECG signal; based on the acquired ECG signal, adjusting the distal portion of the catheter to a second position different from the first position; identifying at least one first electrode of the plurality of electrodes to stimulate a first nerve; identifying at least one second electrode of the plurality of electrodes to stimulate a second nerve; and stimulating at least one of the first and second nerves to cause a contraction of a respiratory muscle.Type: ApplicationFiled: February 27, 2020Publication date: June 18, 2020Applicant: Lungpacer Medical Inc.Inventors: Viral S. THAKKAR, Douglas G. EVANS, Matthew J. GANI
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Publication number: 20200188659Abstract: This disclosure describes methods and systems for preventing, moderating, and/or treating brain injury. The methods herein may include obtaining a test result reflecting a condition of a brain in the subject, determining a stimulation parameter based on the test result, and stimulating a nerve based on the stimulation parameter, wherein stimulation of the nerve assists or causes contraction of a respiratory muscle in the subject. The systems herein may include a processor configured to: receive a test result reflecting a condition of a brain in a subject, and determine a stimulation parameter based on the test result; and a stimulator configured to stimulate a nerve based on the stimulation parameter, wherein stimulation of the nerve assists or causes contraction of a respiratory muscle in the subject.Type: ApplicationFiled: February 27, 2020Publication date: June 18, 2020Applicant: Lungpacer Medical Inc.Inventors: Douglas G. EVANS, Viral S. THAKKAR, Matthew J. GANI
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Publication number: 20200188660Abstract: An injectable electrode which is manufactured in the body by curing from a liquid phase to a solid phase, and therefore molding to the contours of the bodily structures where it is injected.Type: ApplicationFiled: June 8, 2018Publication date: June 18, 2020Inventors: Manfred FRANKE, Andrew J. SHOFFSTALL, Elias VEIZI, John w. SHEETS
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Publication number: 20200188661Abstract: The present disclosure provides a device for state-dependent pudendal nerve stimulation for bladder control in a subject and methods of making and using the same.Type: ApplicationFiled: July 23, 2018Publication date: June 18, 2020Applicant: Duke UniversityInventors: Warren M. GRILL, James A. HOKANSON, Christopher L. LANGDALE
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Publication number: 20200188662Abstract: Embodiments of the invention provide apparatus, systems and methods for facilitating introduction of a urinary drainage catheter (UDC) into the urinary tract (UT). One embodiment provides a UDC including electrodes for delivering high frequency current to a patient's pudendal nerves to relax the urinary sphincter (US) before passing the UDC therethrough so as reduce the resistance force on the UDC and discomfort to the patient. The electrodes can comprise at least one pair of bipolar electrodes and may be flexible so as to bend and flex within the urethra. The UDC includes one or more lumens including a drainage lumen and an inflation lumen for inflating an anchoring device on the UDC. The UDC can include a pressure sensor to assess relaxation of the US. The UDC may include a second set of electrodes and irrigation lumen for relaxing the US and flushing the urethra with the UDC in place.Type: ApplicationFiled: January 15, 2020Publication date: June 18, 2020Inventor: Mir Imran
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Publication number: 20200188663Abstract: An apparatus for relieving pain in a region of the body of a user by contacting electrodes to a surface of the body of the user at the region and providing a series of electrical impulses to the region, the apparatus including: (a) at least two electrodes adapted to contact a surface of a body of the user; (b) a control unit; and (c) a signal generator, associated with the control unit and responsive thereto, the signal generator and the control unit adapted to operative connect to a power supply, the signal generator adapted, in an operative mode, to provide a series of electrical impulses to the surface of the body, via the electrodes, the series including a plurality of cycles, each of the cycles having a positive voltage pulse and a negative voltage pulse, wherein a frequency of the plurality of cycles is optionally within a range of 60-150 cycles per second, wherein a time-averaged voltage amplitude (Vap) of the positive voltage pulse, over an entire duration (Tppositive) thereof, is 20-90 Volts, and wheType: ApplicationFiled: August 15, 2017Publication date: June 18, 2020Inventors: Zvi NACHUM, Shalom LAMPERT
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Publication number: 20200188664Abstract: A computer implemented method for detecting pocket stability for an implantable cardiac monitor, including under control of one or more processors in the ICM, collecting impedance data over at least one cardiac cycle. The impedance data is processed to separate an impedance waveform that varies over the at least one cardiac cycle in a manner representative of cardiac functionality over the at least one cardiac cycle. A characteristic of interest is analyzed from the impedance waveform over the at least one cardiac cycle. A pocket stability state of the ICM is identified and recorded based on the analyzing operation.Type: ApplicationFiled: December 18, 2018Publication date: June 18, 2020Inventors: Jong Gill, Fujian Qu, Stuart Rosenberg
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Publication number: 20200188665Abstract: Portable high-voltage electrical stimulation devices and systems are disclosed that are scalable to utilize a minimal number of output channels to a large number of output channels. The devices and systems include a high-voltage power supply and output pulse circuitry comprising a plurality of output channel circuits. The electrical stimulation devices and systems disclosed herein also provide improved safety features, including an optional safety monitor.Type: ApplicationFiled: December 10, 2019Publication date: June 18, 2020Inventors: Nicholas Annetta, Jeffrey Weisgarber, Noah Lemire, Matthew Edward Mowrer, Albert E. Weller, III, Alexander Campean, Matthew Staub, Andrew M. Schimmoeller, Jeffrey A. Friend
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Publication number: 20200188666Abstract: A method of forming an electrode array includes the steps of positioning a workpiece on a mold part, compressing the workpiece into the mold part to form a contact, and introducing resilient material into the mold part to form a flexible body.Type: ApplicationFiled: August 11, 2016Publication date: June 18, 2020Inventor: Matt V. Krywcun
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Publication number: 20200188667Abstract: An exemplary evoked response measurement system includes a sound processor external to a patient and configured to direct a cochlear implant implanted within the patient to apply electrical stimulation to the patient. The measurement system also includes a headpiece configured to connect to the sound processor by way of a cable, affix to an external surface of a head of the patient, and facilitate wireless communication between the sound processor and the cochlear implant. The measurement system also includes a plurality of conductive contacts communicatively coupled to the sound processor and affixed to the external surface of the head of the patient to detect a signal representative of an evoked response generated by a brain of the patient in response to the electrical stimulation. At least one conductive contact is physically coupled to the headpiece and located between the headpiece and the external surface of the head of the patient.Type: ApplicationFiled: February 29, 2016Publication date: June 18, 2020Inventor: Kanthaiah Koka
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Publication number: 20200188668Abstract: A cochlear implant, for use with a micro camera, including a stimulation assembly, a cochlear lead with an electrode array, a lens associated with the distal region of the electrode array, an optical fiber bundle that extends proximally from the lens and outwardly from the proximal region of the cochlear lead, a camera interface in which the proximal end of the optical fiber bundle is located and that is configured to receive the micro camera, and at least one illumination guide that extends from the camera interface to the cochlear lead.Type: ApplicationFiled: March 6, 2019Publication date: June 18, 2020Inventors: Martin Grossoehmichen, Konstantin Silberzahn, Tim Nauwelaers, Volkmar Hamacher
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Publication number: 20200188669Abstract: An exemplary sound processor 1) divides an audio signal into M analysis channels, 2) generates M fine structure signals corresponding to the M analysis channels, wherein each fine structure signal included in the M fine structure signals represents fine structure information for a different analysis channel included in the M analysis channels, and 3) selects, based on the M fine structure signals, only N analysis channels included in the M analysis channels for presentation to the patient during a stimulation frame, wherein N is less than M. Corresponding systems and methods are also disclosed.Type: ApplicationFiled: May 31, 2016Publication date: June 18, 2020Inventors: Leonid M. Litvak, Nobutaka Okuyama
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Publication number: 20200188670Abstract: Described are systems and methods for preventing, diagnosing, and/or treating one or more medical conditions. The medical conditions can be ocular and/or neurological diseases, disorders, and/or conditions. The systems and methods can employ a microstimulator that is configured to be placed within an anatomical structure of a subject. The microstimulator can be capacitively linked to an external electronic device to provide neuromodulation to a biological target site proximal to the anatomical structure. The microstimulator can include a body and an electrically conductive insert arranged within the body to create a capacitively coupled link with the external electronic device. The electrically conductive insert can receive a power signal from an external electronic device and convert the power signal to deliver a therapy signal to the biological target site.Type: ApplicationFiled: December 22, 2017Publication date: June 18, 2020Inventors: Anthony V. Caparso, Malik Kahook, Naresh Mandava, Noah Lemire, Adam Farwick, Steve Wilder, Steve Risser
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Publication number: 20200188671Abstract: The present disclosure relates to a method for modulating the nervous system in order to reduce inflammation. The method includes delivering a vagus nerve stimulation (VNS) therapy to a vagus nerve of a patient for the treatment of inflammation according to a first set of parameters. The method further includes delivering a secondary nerve stimulation (SNS) therapy to a secondary nerve of the patient for the treatment of a sleep disorder according to a second set of parameters different from the first set of parameters.Type: ApplicationFiled: December 11, 2019Publication date: June 18, 2020Applicant: LivaNova USA, Inc.Inventor: Eric Lovett
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Publication number: 20200188672Abstract: The present disclosure relates to the treatment of patients with Parkinson's Disease using subthalmic nucleus deep brain stimulation to a specific region of the brain. By positioning the electrode in the margin of the dorsal-lateral and anterior region of the subthalamic nucleus, improved benefits are obtained.Type: ApplicationFiled: March 27, 2018Publication date: June 18, 2020Applicant: VANDERBILT UNIVERSITYInventors: David CHARLES, Mallory HACKER, Peter KONRAD
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Publication number: 20200188673Abstract: Systems and methods for managing pain in patient are described. A system may include sensors configured to sense physiological or functional signals, and a pain analyzer to generate signal metrics from the physiological or functional signals. The pain analyzer also generates weight factors corresponding to the signal metrics. The weight factors may indicate the signal metrics reliability in representing an intensity of the pain. The pain analyzer generates a pain score using a plurality of signal metrics and a plurality of weight factors. The pain score may be output to a user or a process. The system may additionally include an electrostimulator to generate and deliver closed-loop pain therapy according to the pain score.Type: ApplicationFiled: February 25, 2020Publication date: June 18, 2020Inventors: Pramodsingh Hirasingh Thakur, Jianwen Gu, Bryan Allen Clark, David J. Ternes, David L. Perschbacher, James John Kleinedler, Elizabeth Mary Annoni
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Publication number: 20200188674Abstract: Systems and methods for monitoring and treating patients with heart failure are discussed. The system may receive patient atrioventricular (AV) conduction characteristic under different heart rates or patient conditions. Stimulation parameters including stimulation timing parameters may be stored in a memory. The system may include a stimulation control circuit configured to determine a parameter update schedule indicating a timing at which to update stimulation parameter using patient AV conduction characteristic, and dynamically update at least a portion of the stored set of stimulation parameters at the determined parameter update schedule. For a specified heart rate or heart rate range, a stimulation parameter may be selected from the set of the stimulation parameters for use during cardiac stimulation.Type: ApplicationFiled: November 25, 2019Publication date: June 18, 2020Inventors: Qi An, Yinghong Yu
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Publication number: 20200188675Abstract: Disclosed herein are deep-brain stimulation (DBS) systems and methods for the treatment of Tourette Syndrome (TS). The DBS methods described herein comprise a stimulation paradigm that may help to reduce the frequency and/or severity of motor and vocal tics, as well as rapid and involuntary muscle motions that are characteristic of TS. One variation of a method for the treatment of TS comprises adjusting electrical stimulation to a target brain region based on changes or variations in the neural activity signals in the target brain region. One example of a method described herein comprises monitoring the power values (e.g., spectral power values) of one or more frequency bands of the acquired neural activity signals and adjusting electrical stimulation parameters based on at least one variation or change of the monitored power values.Type: ApplicationFiled: December 6, 2019Publication date: June 18, 2020Inventors: Sara Renata Francesca MARCEGLIA, Alberto PRIORI, Mattia ARLOTTI
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Publication number: 20200188676Abstract: A method and apparatus for measuring a bioimpedance and performing an electrical stimulation is provided. The method includes generating a first current corresponding to a first high-frequency, generating a second current corresponding to a second high-frequency, generating a low-frequency current based on a beat phenomenon of the first current and the second current, and calculating an impedance of a target part based on a voltage induced to the target part by a high-frequency current corresponding to at least one of the first current and the second current and the low-frequency current.Type: ApplicationFiled: October 17, 2019Publication date: June 18, 2020Applicant: Samsung Electronics Co., Ltd.Inventors: Hyungwoo LEE, Sang Joon KIM, Jongpal KIM
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Publication number: 20200188677Abstract: Systems and methods for monitoring and treating patients with heart failure are discussed. The system can store in a memory stimulation parameters, including stimulation timing parameters for a plurality of heart rate ranges. The system includes a plurality of timers with respective durations for the plurality of heart rate ranges. A stimulation control circuit can identify a target heart range in which a detected heart rate falls, and measure an atrioventricular (AV) conduction characteristic value in response to the timer for the target heart range being expired at the detected heart rate. The stimulation control circuit can update a stimulation parameter corresponding to the target heart rate range using the measured AV conduction characteristic. The updated stimulation parameter can be used in cardiac stimulation.Type: ApplicationFiled: November 25, 2019Publication date: June 18, 2020Inventors: Qi An, Yinghong Yu, Adam MacEwen
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Publication number: 20200188678Abstract: Embodiments describe herein generally pertain to implantable medical device (IMDs), and methods for use therewith, that can be used to automatically switch an IMD from its normal operational mode to an MRI safe mode, and vice versa, within increased specificity. In certain embodiments, a controller of the IMD uses a magnetic field sensor to determine whether a first magnetic field condition is detected, and uses an accelerometer to determine whether a positional condition is detected. In response to the first magnetic field condition being detected, and the positional condition being detected, the controller can use the magnetic field sensor to determine whether a second magnetic field condition is detected, which differs from the first magnetic field condition. The controller can then cause the IMD to enter the MRI safe mode based at least in part on the first and second magnetic field conditions and the positional condition being detected.Type: ApplicationFiled: February 24, 2020Publication date: June 18, 2020Applicant: Pacesetter, Inc.Inventors: Xing Pei, Brad Lindevig, Stuart Rosenberg, Nima Badie
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Publication number: 20200188679Abstract: One aspect is a system for reception or emission of an electrical signal from or into the human or animal body, comprising at least one insulated electrical conductor; a sleeve-shaped electrode that is electrically connected to the electrical conductor and includes an internal side, an external side, and a channel, wherein the channel defines a longitudinal axis along which the conductor is arranged. According to one embodiment, the conductor extends without interruption along the entire area of the electrode, and the electrode further includes a slit that extends from the internal side to the external side of the electrode and in which the conductor is appropriately arranged in the slit such that the electrode forms a direct durable mechanical and electrical connection to the conductor.Type: ApplicationFiled: December 11, 2019Publication date: June 18, 2020Applicant: Heraeus Deutschland GmbH & Co. KGInventors: Markus Jung, Thorsten Kaiser, Ashkan Hasiri, Katharina Musiol
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Publication number: 20200188680Abstract: A charging system for an Implantable Medical Device (IMD) is disclosed having a charging coil and one or more sense coils. The charging coil and one or more sense coils are preferably housed in a charging coil assembly coupled to an electronics module by a cable. The charging coil is preferably a wire winding, while the one or more sense coils are concentric with the charging coil and preferably formed in one or more traces of a circuit board. The magnitude of one or more voltages induced on the one or more sense coils can be measured to determine the position of the charging coil relative to the IMD, and in particular whether the charging coil is (i) centered, (ii) not centered but not misaligned, or (iii) misaligned, with respect to the IMD being charged, which three conditions sequentially comprise lower coupling between the charging coil and the IMD.Type: ApplicationFiled: February 20, 2020Publication date: June 18, 2020Inventors: Daniel Aghassian, Thomas W. Stouffer
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Publication number: 20200188681Abstract: An implantable medical system for intra-body communication, comprising an implantable first device. The first device comprises a plurality of capacitors and a DC blocking capacitor. The first device is configured to discharge the plurality of capacitors via the DC blocking capacitor in an encoded sequence to generate a signal.Type: ApplicationFiled: November 21, 2019Publication date: June 18, 2020Inventors: Marcelo Baru, Brian M. Taff, Andrew B. Kibler
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Publication number: 20200188682Abstract: An ambulatory medical device configured to analyze heart rates in different operating modes includes a plurality of ECG sensing electrodes, a plurality of therapy electrodes and at least one processor configured to in a default operating mode, perform a default heart rate calculation for determining a heart rate of the patient for use in detecting a cardiac arrhythmia condition of the patient. The at least one processor is configured to change a device operating mode from a default mode based on detecting patient activity to an activity operating mode, and in the activity operating mode, perform a different heart rate calculation from the default heart rate calculation for determining the heart rate for use in detecting the cardiac arrhythmia condition of the patient during the activity operating mode. The at least one processor is configured to deliver the treatment in response to detecting the cardiac arrhythmia condition.Type: ApplicationFiled: November 25, 2019Publication date: June 18, 2020Inventors: Gary A Freeman, Thomas E Kaib, Shane S Volpe
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Publication number: 20200188683Abstract: An external wearable medical device includes an electrode to detect patient cardiac activity; a therapy electrode to provide a therapy in response to detecting an arrhythmia event; a GUI display comprising a caregiver interface and a patient interface; and a processor configured to provide, to the caregiver interface, a first set of information that includes information for operating the device in conjunction with the patient and an alert history of the device including an indication of one or more detected arrhythmia events, provide, to the patient interface, a second set of information that includes information for allowing the patient to cause the device to suspend providing the therapy and a direction to the patient to contact a caregiver responsive to detecting an event affecting at least one of the device and the patient, and responsive to detecting the event, automatically transmitting a notification of the event to an external entity.Type: ApplicationFiled: February 27, 2020Publication date: June 18, 2020Inventors: Trisha A. Pavel, John G. Clark, Edward J. Donnelly, Thomas E. Kaib
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Publication number: 20200188684Abstract: A medical introducer is provided for use in locating an energy delivery probe, such as an RF ablation probe, at a target location in tissue. The introducer includes a proximal hub and an elongate cannula having a distal end and a proximal end, the proximal end connected to the hub. The cannula is formed entirely of an electrically insulating polymer material and includes a tapered distal tip. An RF ablation probe system is also provided that includes an RF ablation probe assembly, a stylet, and the introducer.Type: ApplicationFiled: December 14, 2018Publication date: June 18, 2020Inventors: Ruoya Wang, Ryan Smith, Ken Driver, Samir Merchant
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Publication number: 20200188685Abstract: Methods and systems for treating a biological fluid with light are disclosed. The methods and systems include determining the light dose being delivered to a biological fluid and adjusting the duration of a treatment or the intensity of light emitted in the event of a detected light source outage.Type: ApplicationFiled: December 12, 2019Publication date: June 18, 2020Inventors: Greg Coultas, Christopher J. Wegener, Tanima Jahan Abedin
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Publication number: 20200188686Abstract: The present invention provides for devices and methods of treating wounds, including general wounds, gum disease and gingival tissues post scaling/root planning, using a diode laser which generates a beam of light having a wavelength in the visible portion of the electromagnetic spectrum (400 nm-700 nm). Further disclosed are devices and methods capable of stimulating tissue regeneration at the site of a wound.Type: ApplicationFiled: November 13, 2017Publication date: June 18, 2020Inventor: Margaret Kalmeta
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Publication number: 20200188687Abstract: A cosmetic method of providing light treatment to skin tissue includes: providing an intense pulsed light (IPL) source; interposing a band pass filter between the IPL source and the skin tissue; the band pass filter passes light in a selected range of wavelengths with an average absorption coefficient equivalent to that of a selected laser light source; the method includes activating the IPL source and applying it to the skin tissue, wherein the filtered light impinging on the skin tissue provides equivalent treatment to that of the selected laser light source.Type: ApplicationFiled: December 16, 2018Publication date: June 18, 2020Inventors: Yacov Domankevitz, Israel Schuster
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Publication number: 20200188688Abstract: A light emitting device for a human having a scalp with hair, the device includes a flexible arcuate base configured to contour a portion of the scalp. The base has a width between 20 mm and 120 mm and includes an interior and an interior surface. At least one array of teeth is coupled to the interior surface, each tooth in the at least one array of teeth being pressed against the scalp when the base is contoured about the scalp. Each tooth is configured to part the hair when the at least one array of teeth is pressed against the scalp. An array of at least one of light emitting diodes and laser diodes coupled to the base proximate the at least one array of teeth.Type: ApplicationFiled: February 25, 2020Publication date: June 18, 2020Inventors: David Michaels, Randy Veliky, James Smeriglio, Alena Michaels
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Publication number: 20200188689Abstract: A process for treating highly localized carcinoma cells that provides precise positioning of a therapeutic source of highly ionizing but weakly penetrating radiation, which can be shaped so that it irradiates essentially only the volume of the tumor. The intensity and duration of the radiation produced by the source can be activated and deactivated by controlling the neutron flux generated by an array of electrically controlled neutron generators positioned outside the body being treated. The energy of the neutrons that interact with the source element can be adjusted to optimize the reaction rate of the ionized radiation production by utilizing neutron moderating material between the neutron generator array and the body. The source device may be left in place and reactivated as needed to ensure the tumor is eradicated without exposing the patient to any additional radiation between treatments. The source device may be removed once treatment is completed.Type: ApplicationFiled: February 20, 2020Publication date: June 18, 2020Applicant: Westinghouse Electric Company LLCInventors: John H. NELSON, Michael D. HEIBEL
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Publication number: 20200188690Abstract: Embodiments of the disclosure may be drawn to wireless afterloaders. Exemplary afterloaders may include a central processing unit, a first complex programmable logic device having a memory, a transceiver operably connected to the complex programmable logic device, wherein the transceiver is configured to wirelessly receive data from a second complex programmable logic device separate from the wireless afterloader, and a battery.Type: ApplicationFiled: December 18, 2018Publication date: June 18, 2020Applicant: NUCLETRON OPERATIONS B.V.Inventors: Cor van de WARDT, Johan Henning
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Publication number: 20200188691Abstract: A novel treatment method is disclosed, wherein a patch configured to be placed on a patient's skin is activated, before placement, to deliver localized radiotherapy to a diseased area of the skin. The disclosed devices and methods minimize or prevent collateral damage to the neighboring tissues. In most cases, the disclosed devices and methods include coating a contoured, solid, flexible or conformal substrate with one or more lanthanide elements and then activating (e.g. neutron irradiation) the elements such that its resulting radioisotope emits beta-particles into the diseased skin surface when applied to the patient's skin. Novel processes are described for fabricating and irradiating the lanthanide-based skin patch, for example a holmium-based skin patch.Type: ApplicationFiled: October 18, 2019Publication date: June 18, 2020Inventors: Frédéric Sarazin, Jeramy Zimmerman, Rachel Morneau, Martin Ritter
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Publication number: 20200188692Abstract: A system for generating a dose distribution is provided. The system may obtain a first dose distribution in at least a portion of a subject. The system may also obtain a trained machine learning model. The system may further generate, based on the first dose distribution and the trained machine learning model, a second dose distribution in the at least a portion of the subject, wherein the second dose distribution has a higher accuracy than that of the first dose distribution.Type: ApplicationFiled: December 12, 2019Publication date: June 18, 2020Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventor: Yanfang LIU
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Publication number: 20200188693Abstract: A mobile radiation oncology coach system is disclosed. The mobile radiation oncology coach system comprise a trailer having a control console area and a treatment area, the treatment area is equipped with a medical treatment facility. The mobile radiation oncology coach system further comprise an internal shielding provided between the control console area and the treatment area. The mobile radiation oncology coach system further comprise an external shielding provided at the outside of the trailer.Type: ApplicationFiled: February 26, 2020Publication date: June 18, 2020Applicant: Alliance Oncology, LLCInventors: David Chamberlain, Brent Murphy, Harry Freeman
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Publication number: 20200188694Abstract: A phantom, calibration system and calibration method are described. The phantom having a phantom body and an X-ray luminescent material, wherein at least a portion of the X-ray luminescent material is on a surface of the phantom.Type: ApplicationFiled: February 21, 2020Publication date: June 18, 2020Inventors: Warren Kilby, Petr Jordan, John Noll, Calvin Maurer, JR.
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Publication number: 20200188695Abstract: A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.Type: ApplicationFiled: December 26, 2019Publication date: June 18, 2020Inventors: Yuan-hao LIU, Wei-Iin CHEN, Pei-yi LEE, Ming-chuan CHANG, Wenyu XU
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Publication number: 20200188696Abstract: A method and/or system are provided for improving kidney function and/or increasing Glomerular Filtration Rate (GFR) of the renal system, by applying acoustic and/or ultrasonic energy to one or more of the kidneys. The method suggests either focused or non-focused (or combined) energy delivery, optionally in a noninvasive approach, which could also be implemented invasively and/or by implantable device. Potential applications of this technique, include, but are not restricted to, treatment of renal disorders such as CKD (Chronic Kidney Disease) and/or AKI (Acute Kidney Injury), short term or long term intervention in kidney function for therapeutic or diagnostic purposes, modifying urine output in heart failure, modulating blood volume and/or pressure, and modulating clearance of compounds in the blood are typically difficult to extract from the kidneys, such as iodine, other imaging contrast media, and similar compounds.Type: ApplicationFiled: April 3, 2018Publication date: June 18, 2020Applicant: MDSG Innovation Ltd.Inventors: Benny ROUSSO, Lior ESHEL, Assaf ERELL, Naama WINETRAUB
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Publication number: 20200188697Abstract: In some aspects, a device wearable by or attached to or implanted within a person includes a sensor configured to detect a signal from the brain of the person and a transducer configured to apply to the brain an acoustic signal.Type: ApplicationFiled: December 13, 2019Publication date: June 18, 2020Applicant: EpilepsyCo Inc.Inventors: Eric Kabrams, Jose Camara, Owen Kaye-Kauderer, Alexander B. Leffell, Jonathan M. Rothberg, Maurizio Arienzo, Kamyar Firouzi
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Publication number: 20200188698Abstract: In some aspects, a device wearable by a person includes a sensor configured to detect a signal from the brain of the person and a transducer configured to apply to the brain an ultrasound signal. The ultrasound signal has a low power density and is substantially non-destructive with respect to tissue when applied to the brain.Type: ApplicationFiled: December 13, 2019Publication date: June 18, 2020Applicant: EpilepsyCo Inc.Inventors: Eric Kabrams, Jose Camara, Owen Kaye-Kauderer, Alexander B. Leffell, Jonathan M. Rothberg, Maurizio Arienzo, Kamyar Firouzi
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Publication number: 20200188699Abstract: In some aspects, a device wearable by a person includes a transducer configured to apply to the brain of the person acoustic signals.Type: ApplicationFiled: December 13, 2019Publication date: June 18, 2020Applicant: EpilepsyCo Inc.Inventors: Eric Kabrams, Kamyar Firouzi
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Publication number: 20200188700Abstract: In some aspects, a device wearable by or attached to or implanted within a person includes a sensor configured to detect an electroencephalogram (EEG) signal from the brain of the person and a transducer configured to apply to the brain a low power, substantially non-destructive ultrasound signal.Type: ApplicationFiled: December 13, 2019Publication date: June 18, 2020Applicant: EpilepsyCo Inc.Inventors: Eric Kabrams, Jose Camara, Owen Kaye-Kauderer, Alexander B. Leffell, Jonathan M. Rothberg, Kamyar Firouzi
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Publication number: 20200188701Abstract: In some aspects, a device includes a sensor configured to detect a signal from the brain of the person and a plurality of transducers, each configured to apply to the brain an acoustic signal. One of the plurality of transducers is selected using a statistical model trained on data from prior signals detected from the brain.Type: ApplicationFiled: December 13, 2019Publication date: June 18, 2020Applicant: EpilepsyCo Inc.Inventors: Eric Kabrams, Kamyar Firouzi, Mohammad Moghadamfalahi
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Publication number: 20200188702Abstract: In some aspects, a device includes a sensor configured to detect a signal from the brain of the person and a plurality of transducers, each configured to apply to the brain an acoustic signal. One of the plurality of transducers is selected using a statistical model trained on signal data annotated with one or more values relating to identifying a health condition.Type: ApplicationFiled: December 13, 2019Publication date: June 18, 2020Applicant: EpilepsyCo Inc.Inventors: Eric Kabrams, Kamyar Firouzi, Mohammad Moghadamfalahi
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Publication number: 20200188703Abstract: A probe for ultrasound treatment of skin laxity are provided. Systems and methods can include ultrasound imaging of the region of interest for localization of the treatment area, delivering ultrasound energy at a depth and pattern to achieve the desired therapeutic effects, and/or monitoring the treatment area to assess the results and/or provide feedback. In an embodiment, a treatment system and method can be configured for producing arrays of sub-millimeter and larger zones of thermal ablation to treat the epidermal, superficial dermal, mid-dermal or deep dermal components of tissue.Type: ApplicationFiled: February 21, 2020Publication date: June 18, 2020Inventors: Peter G. Barthe, Michael H. Slayton, Inder Raj S. Makin