Abstract: A method of repairing a heart valve provides intravascular access for repair of a heart valve through a ventricular trans-septal approach. An external guide catheter can be inserted through a vein of a patient into the right ventricle via the right atrium. An internal guide catheter can be inserted through the external guide and can provide access to the septum for a puncture tool to create an opening through the septum to the left ventricle. The internal guide can then be advanced into the left ventricle and used to guide a deployment catheter that deploys a repair device onto the heart valve.

Abstract: A constricting cord can be delivered to the vicinity of an annulus using an apparatus that includes a set of support arms, with a respective anchor launcher supported by each of the support arms. An inflatable first balloon is configured to push the support arms away from each other when the first balloon is inflated. An inflatable second balloon is mounted to a shaft and is configured for inflation when the second balloon is disposed distally beyond the first balloon. In some embodiments, the distal balloon is inflated while it is in a ventricle. In some embodiments, the distal balloon is inflated while it is in a pulmonary artery.

Abstract: A heart valve sizing ring is disclosed. The sizing ring includes an outer ring and an inner ring configured and arranged to couple to the outer ring. A tubular portion extends from the inner ring and has a plurality of suture holders arranged about an upper end thereof. The outer ring and inner ring having a pair of complementary mating surfaces configured and arranged to grip sutures therebetween when coupled together. When coupled around sutures, the assembled ring may be tightened down against the heart valve to test the fit as if the sizing ring were a similarly sized prosthetic heart valve ring. Commissures of the heart valve may be suspended from the suture holders of the tubular portion. The surgeon can then remove the sizing ring and replace it with a prosthetic ring.

Abstract: A device is for containing a bone graft material. The device includes a mesh outer sleeve extending longitudinally from a proximal end to a distal end and sized and shaped to correspond to a profile of an outer surface of a target bone. The outer sleeve includes a plurality of openings extending therethrough, longitudinally adjacent ones of the plurality of openings being offset from one another relative to a longitudinal axis of the device. The device also includes a mesh inner sleeve connected to an interior surface of the outer sleeve via at least one strut so that a bone graft collecting space is defined therebetween The inner sleeve is sized and shaped to correspond to a profile of a medullary canal of the target bone. The inner sleeve includes a plurality of openings extending therethrough.

Abstract: Provided is a compression resistant implant configured to fit at or near a bone defect to promote bone growth, the compression resistant implant comprising porous ceramic particles in a biodegradable polymer, and an oxysterol disposed in or on the compression resistant implant. Methods of making and use are further provided.

Abstract: Exemplary embodiments are directed to an augment and methods of implanting an augment. The methods include inserting the augment into a bone cavity of a bone of a host. The augment includes a body with an outer surface and at least one hole preformed in the body. The method includes introducing a fastener from an outer surface of the bone into a hole formed in the bone and engaging the fastener with the hole of the bone. The method includes passing the fastener through the hole of the bone. The method includes introducing into and engaging the fastener with the at least one hole in the body of the augment to fixate the augment within the bone cavity.

Abstract: The methods disclosed herein of generating three-dimensional lattice structures and reducing stress shielding have applications including use in medical implants. One method of generating a three-dimensional lattice structure can be used to generate a structure lattice and/or a lattice scaffold to support bone or tissue growth. One method of reducing stress shielding includes generating a structural lattice to provide sole mechanical spacing across an area for desired bone or tissue growth. Some examples can use a repeating modified rhombic dodecahedron or radial dodeca-rhombus unit cell. Some methods are also capable of providing a lattice structure with anisotropic properties to better suit the lattice for its intended purpose.

Abstract: Systems and methods for modifying a shoulder joint configuration exhibiting wear that take into account resultant of forces responsible for the wear of the glenoid surface from geometric characteristics of wear.

Abstract: The glenohumeral component of the invention comprises a first side and a second side, which are opposite each other and which, in an implanted state in which the glenohumeral component is free-floating with respect to a humerus and a glenoid of a human shoulder, are in contact respectively with an end portion of the humerus and with a glenoid component intended to be secured to the glenoid. The first side of the glenohumeral component includes a convex articular surface that is designed to articulate with a concave bone surface prepared within the end portion of the humerus. The second side of the glenohumeral component includes a concave articular surface that is designed to articulate with a convex articular surface of the glenoid component. The corresponding shoulder prosthesis is thus reversed.

Abstract: A hand manipulated endoscopic medical device is disclosed. The medical device includes a body having a proximal end, which is hand manipulated, and a distal end which includes a manipulator. A light emitting device is centrally disposed at the distal end. An imaging device is centrally disposed at the distal end for imaging at least a portion of the region illuminated by the light emitting device. Also disclosed is a tool for extracting an artificial lumbar disc from between a pair of vertebral plates. The extraction tool includes a handle, a member for transmitting force, and a sharpened end, specially configured to be placed between the artificial disc and the vertebral plate. Further disclosed is a tool for implanting or explanting a ball to or from an artificial lumbar disc. The implanter/explanter includes a pinion shaft and a pinion shaft enclosure. A tightening knob is disposed at the proximal end of the shaft enclosure and coupled to the pinion shaft.

Abstract: The invention discloses an artificial epistropheus support body comprising a support. The support comprises a crown part and a body part, a top surface of the crown part forms a top profiling surface, and a bottom surface of the body part forms a bottom profiling surface; the support has a cavity inside thereof, and a micro-hole grid stent is arranged in the cavity; the cavity forms a plurality of windows on the surface of the support. The bottom end of the body part is provided with a lower fixing lug, while the upper end of the crown part is provided with an upper fixing lug; both the lower fixing lug and the upper fixing lug are provided with fixing holes. The artificial epistropheus support body possesses good stability for supporting and reconstructing, it also can prevent a prosthesis from loosening and failing after surgery.

Abstract: The present disclosure relates to an interspinous omnidirectional dynamic stabilization device, including a first fixing part, a second fixing part, a connecting structure and an elastic structure. The first fixing part and the second fixing part are fixedly connected to each other through the connecting structure and elastic structure. The bottoms of the first fixing part and the second fixing part are provided with one or more barbs. The elastic structure is made up of one or more U-shaped structures connected to each other. The first fixing part and the second fixing part are provided with fixing holes respectively.

Abstract: A bone expandable device comprises two expanding members, a retractable member and a fastener. The two expanding members are joined together for forming a cavity therebetween, each the expanding member includes two flexible parts and a fixed part. The two flexible parts are connected to the fixed part separately, and each the flexible part can be bent from the fixed part. The retractable member is disposed in the cavity and includes a first part and a second part. The first part is movably sleeved on the second part, and a length of the retractable member can be adjusted by moving the first part or the second part. The fastener is for fastening the two expanding members together. When the length of the retractable member is increasing, the two opposite ends of the retractable member would push against the four flexible parts to expand the flexible parts outwardly from the cavity.

Abstract: The present invention provides a device and methodology for use in spinal fusion surgeries. An implant is proved for forming a rigid structure between adjoining vertebrae in a patient. The implant is a cage defined by at least a first end, second end, first side, and second side surface, wherein first and second side surfaces extend substantially parallel to each other to span a space between adjoining vertebrae and first and second ends interconnect said first side surface and second side surface. The cage incorporates one or more flexible joints that allow the cage to be deformed for insertion into a patient. The ability to deform the cage allows a greater ease and flexibility in inserting and positioning the implant.

Abstract: An implant includes a central wall extending from a first side of a peripheral frame portion to a second side of the peripheral frame portion, and a first helical bone contacting member attached at the central wall and disposed within the superior half of the implant. The implant further includes a first support member attached at the central wall at a junction coincident with the first helical bone contacting member and extending to a central region of the implant internal to the first helical bone contacting member. In addition, the implant includes a non-helical bone contacting member extending from a portion of the first support member that is disposed internal to the first helical bone contacting member.

Abstract: A device and method for inserting a liner into an acetabular cup. The device includes a first portion configured to engage the liner and a rim of the acetabular cup to align a pole of the liner and a pole of the cup along an axis of the device prior to insertion of the liner into the cup. The device also includes a second portion for pushing the liner into the cup. The second portion includes a guide arrangement for engaging a rim of the liner. The second portion is coupled to the first portion for movement of the second portion with respect to the first portion along said axis.

Abstract: An instrument and inserter kit for providing a load to insert or retract an implant 2000 is provided. The instrument includes a cover having an engagement end opposite a distal end. The engagement end is configured to mount to an engagement feature of a handle of an inserter. The cover is an elongated member having a C-shaped profile having a dimension configured to receive a sliding member. The sliding member is seated over the cover and is weighted. The sliding member is configured to slide between a first radial lip and a second radial lip so as to provide an impacting force or retracting force on the instrument.

Abstract: Methods of implanting a prosthesis to repair a joint include displacing a first bone from the joint formed by an intersection between the first bone and a second bone. An end portion of the first bone is resected to define a resected end. A concavity is formed into the resected end using a shaping tool. The bone is compacted to form a support layer lining the concavity. The prosthesis is implanted in the concavity against the support layer without attaching the prosthesis to the support layer. The joint is reformed with the prosthesis such that the prosthesis remains unattached to the support layer and the first and second bones articulate about the prosthesis.

Abstract: The present invention provides a three-dimensional bioprinter for fabricating cellular constructs such as tissues and organs using electromagnetic radiation (EMR) at or above 405 nm. The bioprinter includes a material deposition device comprising a cartridge for receiving and holding a composition which contains biomaterial that cures after exposure to EMR. The bioprinter also includes an EMR module that emits EMR at a wavelength of about 405 nm or higher. Also provided is a bioprinter cartridge which contains cells and a material curable at a wavelength of about 405 nm or greater. The cells are present in a chamber and are extruded through an orifice to form the cellular construct.

Abstract: Prosthetic devices and methods of controlling the same are provided. A prosthetic ankle device includes a foot unit and lower limb member moveable relative to one another and defining an ankle angle therebetween. The prosthetic ankle device further includes a controller to operate the device based on weight shifting. Methods of controlling the prosthetic ankle device include operating the device at different ankle angles depending on weight shifting of the user while standing or stopped.

Abstract: A prosthetic system includes a prosthetic foot with a foot member defining a first end portion, a second end portion, and an intermediate portion defining a curvature and extending between the first and second end portions. A pump mechanism is coupled to the foot member. The pump mechanism includes a housing defining a cavity, and a membrane situated in the cavity. The pump mechanism is movable between an original configuration and an expanded configuration. A movable member includes a first portion coupled to the membrane and a second portion arranged to slidably engage the foot member. Relative movement between the first and second end portions moves the first portion of the movable member relative to the housing and slides the second portion along a length of the foot member to shift the pump mechanism between the original and expanded configurations.

Abstract: Deflection devices, systems, and methods for the prevention of stroke. Devices hereof comprise an extension portion and an anchor portion, both of which are configured to prevent the device from advancing into the artery extending from the aortic arch in which the device may be positioned. Additionally, a retrieval system is provided, the system comprising a sleeve catheter and a retrieval device slidably disposed therein. The distal end of the retrieval device comprises one or more attachment portions configured to engage at least a portion of the anchor portion of a device positioned within an artery extending from the aortic arch.

Abstract: Medical devices that include a tubular member with a plurality of braided filaments, each filament crossing another of the filaments at a respective crossing point forming sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm, the pores have an average pore size that is less than or equal to about 500 microns when the tubular member is in an expanded state, the filaments possessing antithrombogenic surfaces to increase antithrombogenicity of the medical device with pores substantially free of webs formed by antithrombogenic material, such that fewer than 5% of the crossing points have webs formed by antithrombogenic material thereby permitting the pores to be substantially free of webs.

Abstract: An intravascular stent, preparation method and use thereof. The intravascular stent includes a positioning segment and a supporting segment. The positioning segment includes a plurality of first repeating elements. The supporting segment includes at least two supporting units and at least one connecting unit. The supporting unit includes a plurality of second repeating elements. The number of the first repeating elements differing from the number of the second repeating elements. A plane formed by front ends of the plurality of first repeating elements being vertical to or intersecting with the axis of the intravascular stent. The intravascular stent is usable for iliac vein, with good supporting effect for iliac vein and less damage to venous wall, and can effectively avoid forming in-stent secondary thrombosis after intravascular stent implantation. Moreover, the intravascular stent is positionable in the iliac vein to improve the accuracy of the release.

Abstract: Medical systems and related methods are disclosed. In some embodiments, the medical systems include an inner tubular member defining an aperture and an outer tubular member at least partially surrounding the inner tubular member. The inner and outer tubular members can be arranged such that an implantable medical endoprosthesis can be disposed therebetween.

Abstract: The present disclosure is directed to a branched endoprosthesis comprising a graft component and at least one support component. In various embodiments, the branched endoprosthesis comprises a body portion and a plurality of leg portions, wherein the legs are in an aligned configuration for ease of cannulation. In various embodiments, at least one leg is in an open configuration for ease of cannulation. Cannulation methods are also described.

Abstract: A stent delivery system can include a core member, an introducer sheath, and a microcatheter. The core member can have a first section and a second section distal to the first section. The second section can have a bending stiffness per unit length that is less than a bending stiffness per unit length of the first section. The introducer sheath can have a lumen configured to receive the core member therethrough. The introducer sheath can have a length of at least about 80 cm. The microcatheter can have a lumen and a proximal end configured to interface with a distal end of the introducer sheath for delivering the core member into the microcatheter lumen.

Abstract: The present embodiments provide systems and methods for deploying at least a portion of a stent, comprising a retaining member having a main body. At least one slot is formed into the main body. The at least one slot comprises a circumferentially enclosed segment and an axial opening. A portion of a stent is restrained from moving radially outward when disposed within the circumferentially enclosed segment, and the portion of the stent is self-expandable radially outward when aligned with the axial opening.

Abstract: Catheter systems and methods for deployment of an endoluminal prosthesis in a body lumen of a patient while maintaining control of a position of the endoluminal prosthesis during the deployment process. Some of the systems and methods are configured to minimize frictional forces of components of the catheter systems during deployment procedures.

Abstract: A surgical or laparoscopic method of treating obesity of a patient using a device adapted to stretch a portion of the stomach wall of said patient. The method comprising the steps of: cutting a hole in the abdominal wall of said patient, dissecting an area around the stomach, placing said device in contact with the stomach, and fixating, direct or indirect, through invagination of the stomach wall, said device to the stomach wall such that said device can stretch a portion of said stomach wall.

Abstract: A scoliosis activity suit includes a body-wrapping portion and a correction portion. The correction portion has a front segment, a rear segment, a shoulder-pulling segment, a chest-pressing segment, a pelvis-lifting segment, and a upper trapezius pressing segment. The shoulder-pulling segment, the chest-pressing segment, the pelvis-lifting segment, and the upper trapezius pressing segment are formed on a front side of the body-wrapping portion and extend to the rear segment of the correction portion. To users with scoliosis, the correction portion generates a 3D compression force on different portions of the spine of the user, such that a backward pulling force against a protracted portion of the shoulder, an uplifting force against an inclined portion of the pelvis, and a pulling force against portions with spinal sidebend can be provided. Besides, being lightweight and easy for users to wear, the suit fulfills practice of daily life adjustment and correction for scoliosis.

Abstract: A collapsible splint includes an expandable frame within a flexible generally rectangular sleeve. The expandable frame includes a number of members that are extendable rods or tubes. The members are oriented longitudinally within the sleeve and arranged transversely across the sleeve and adjacent to one another. The rods are secured at one end of the sleeve and are connected to one another by transverse links to form the frame. The sleeve includes an opening through which the frame can be accessed and extended to a desired length. The sleeve also includes straps on its rear side suitable for binding the collapsible splint around a fractured limb.

Abstract: An orthosis (10) for correcting deformities in the head shape of babies and young children includes a mesh layer (20). The mesh layer (30) includes regions of varying stiffness in the mesh layer that are adapted to apply varying pressure to a wearer's head, so as to restrict undesirable growth and allow desired growth to correct the deformities. Accordingly, the mesh layer (30) provides a layer of uniform thickness but variable stiffness, so that a lightweight means of applying appropriate pressure to the wearer's head is provided. The mesh layer (30) can be manufacturer by 3D printing, based on a scan of the wearer's head.

Abstract: A hand cover includes a protective housing secured to an adjustment mechanism. The protective housing inhibits contact between the hand and the external environment. The adjustment mechanism secures the hand cover to the user. An optional upper access aperture provides air circulation and access to the hand. An optional lateral access aperture also provides access to the hand. An optional positioning mechanism helps maintain the hand cover in place. Attachment anchors for restraints or exercise bands may be provided and devices for orienting and securing IV lines may be provided.

Abstract: An invention concerns a moisture control in a cryotherapy system and creating of snow mist. The system comprises a treatment chamber for at least one person, a closable entry to the treatment chamber, and a cooling apparatus. The cooling apparatus comprises an evaporator configured to function with a coolant and a valve for flow control of the coolant, wherein the evaporator is placed in the treatment chamber and the valve is coupled to the evaporator. The system further comprises a ventilation aperture for obtaining an additional air into the treatment chamber, the ventilation aperture being placed far from the evaporator to such spot that the additional air flows from the ventilation aperture towards the centre of the treatment chamber and simultaneously mixes with an air included in the treatment chamber so that water vapour of the additional air changes from gas to solid ice crystals and forms snow mist in the treatment chamber.

Abstract: Protective clothing and apparel for pets and animals, and method of using same, structured as a shirt and/or hat made of an ultraviolet protective rash guard material with at least on portion having cooling crystals integrated therein. In a first embodiment the clothing is directed to a pet shirt constructed having a top portion, bottom portion, and side portions arranged to form a generally tubular member having an opened torso end, two leg members, and a collar member. In a second embodiment the clothing is directed to a pet hat constructed having a top portion, side portions and a front portion having a visor member attached thereto, the side portions having a lower rim. Two ear members and securement means are integrated within the lower rim of the side portions. At least a portion of the shirt/hat comprises ultraviolet properties. Additionally, at least a portion of the shirt/hat comprises a cooling zone formed of a plurality of cooling crystals.

Abstract: Provided is a multilayer film for a disposable body warmer outer bag, and a disposable body warmer, which are excellent in gas barrier property that inhibits permeation of oxygen gas, water vapor and the like, which can allow swelling due to hydrogen gas generated during a storage period to be prevented, and which are excellent in seal strength, impact resistance and weather resistance. A disposable body warmer outer bag formed from a multilayer film comprising a first barrier layer (10) and a second barrier layer (20), wherein the first barrier layer (10) and the second barrier layer (20) consist of a polyvinylidene chloride layer (12) or a polyvinylidene chloride layer (22) obtained by coating at least one surface (upper portion in FIG. 1) of a heat-resistant resin substrate (11) or a heat-resistant resin substrate (21) with polyvinylidene chloride.

Abstract: A method and assembly for attaching to a container and configured to reduce the volume of a droplet of fluid ejected from the container wherein the assembly is securable to the container without alteration of the container and wherein the volume of the droplet is reduced on a microliter scale. The assembly comprises a base for securing a neck of the container; a tip for securing over a dispensing outlet of the container; and optionally a cap for securing over the tip and connecting to the base.

Abstract: A system to provide high pressure air to the eye during ocular surgery. The system has an air tube, a piece 1, a piece 2 and a plurality of adjustable aperture. Piece 1 has a plurality of piece 1 air feeding tubes, a piece 1 adjustable apertures and a plurality of air ejecting nozzles. Piece 2 comprises a piece 2 air feeding tubes, a piece 2 adjustable aperture, a diameter controlled adjustable aperture and a plurality of valves. Both piece 1 and piece 2 are used separately or simultaneously. Piece 1 is used laterally and piece 2 is used vertically. A humidifies high pressure air is provided to piece 1 and piece 2 air feeding tubes by an air source. The high pressure air provided is humidified controlled high pressure air.

Abstract: A system for preparation of an implant and ab interno insertion of the implant into an eye including a handle having one or more actuators and an elongated shaft having an outer sheath and an elongate member positioned within a lumen of the tubular outer sheath. The system includes a recess sized for holding a patch of material fixed relative to the handle and a cutting member movable relative to the handle and to the recess. The cutting member cuts the patch of material into an implant as the cutting member moves towards a cutting configuration. The implant, once cut, is axially aligned with the lumen of the tubular outer sheath. The inner elongate member is movable relative to the tubular outer sheath to advance the implant into a deployment position in the lumen of the tubular outer sheath for delivery into the eye. Related devices and methods are provided.

Abstract: The present disclosure is related to a treatment probe and method for treating dry eye. The treatment probe may include a thin stainless steel tip, a spacer to ensure proper contact and protect the skin of a patient, a sensor to provide temperature feedback to the power supply providing RF energy to the treatment probe. The treatment focuses on a patient's temple and periorbital area.

Abstract: An ophthalmological laser treatment system comprising a laser source (2) for producing laser radiation, a light projector (3) for focusing the laser radiation onto a focus (F) and a scanner system (5) for moving the focus (F) along a work line (p) comprises a monitoring system (6), which comprises a light detector (60) and is configured to monitor, by way of a light path (r), a monitored region (m) moving together with the focus (F). The monitoring system (6) is configured to monitor a monitored region (m), which moves together with the focus (F) with a fixed geometric assignment to the focus (F) and is for example disposed upstream of the focus (F) in the work direction and not yet worked on by laser radiation.

Abstract: A steerable laser probe may include a handle having a handle proximal end and a handle distal end, an actuation structure of the handle, a housing sleeve, a shape memory sleeve at least partially disposed within the housing sleeve, and an optic fiber disposed within the shape memory sleeve and within an inner bore of the handle. A compression of the actuation structure may be configured to gradually curve the optic fiber. A compression of the actuation structure may be configured to gradually straighten the optic fiber. A decompression of the actuation structure may be configured to gradually curve the optic fiber. A decompression of the actuation structure may be configured to gradually straighten the optic fiber.

Abstract: A steerable laser probe may include a handle, an actuation structure having an actuation structure distal end and an actuation structure proximal end, a housing tube, a first housing tube portion of the housing tube having a first stiffness, a second housing tube portion of the housing tube having a second stiffness, and an optic fiber disposed within an inner bore of the handle and the housing tube. An extension of the actuation structure distal end relative to the actuation structure proximal end may be configured to gradually curve the housing tube and the optic fiber. A retraction of the actuation structure distal end relative to the actuation structure proximal end may be configured to gradually straighten the housing tube and the optic fiber.

Abstract: System and method of photoaltering a region of an eye using an enhanced contrast between the iris and the pupil of the imaged eye. The system includes a laser assembly outputting a pulsed laser beam, a user interface displaying one of a first digital image of the eye and a second digital image of the eye, and a controller coupled to the laser assembly and the user interface. The first digital image has a first contrast between the pupil and the iris, and the second digital image has a second contrast between the pupil and the iris. The controller selectively increases the first contrast between the pupil and the iris to the second contrast between the pupil and the iris and directs the pulsed laser beam to the region of the eye based on one of the first and second digital images.

Abstract: An insertion system includes a handle assembly and a nose assembly removably attached to the handle assembly and including an insertion end. The handle assembly includes a main body, a nose interface and an actuating element. The nose assembly includes a nose, a positioning rod extending from the nose to a distal end, a cutting sheath surrounding a distal end of the positioning rod and including a cutting edge, an actuation member having a proximal end coupled to the actuating element when the nose assembly is attached to the handle assembly and a distal end attached to the cutting sheath, a ventilation tube positioned distal to the distal end of the positioning rod and proximal to the insertion end. The cutting sheath retracts from around the ventilation tube and along the positioning rod when the actuating element on the handle assembly is moved.

Abstract: A super-absorbent dressing assembly for use with a reduced-pressure wound treatment system includes a breathable, fluid restricted dry layer for placement against a wound, a super-absorbent layer, and a non-breathable layer, and a drape extending over the non-breathable layer. A reduced-pressure interface is available to fluidly couple the super-absorbent layer to a reduced-pressure subsystem. The super-absorbent dressing assembly preferably supplies a compressive force when placed under reduced pressure. A reduced-pressure treatment system uses a super-absorbent bolster to treat wounds, e.g., linear wounds.

Abstract: Embodiments disclosed herein are directed to negative pressure treatment systems and wound dressing systems, apparatuses, and methods that may be used for the treatment of wounds. In particular, some embodiments are directed to improved wound dressings comprising a bridge portion connecting two or more portions of an absorbent layer that facilitates trimming of the wound dressing to suitable sizes. Some embodiments provide for trimming the dressing in a gap between two or more portions of an absorbent layer and sealing the exposed portion of dressing after trimming when the dressing is applied to skin surrounding a wound.

Abstract: A dressing for treating tissue with negative pressure may be a composite of dressing layers, including a release film, perforated gel layer, a perforated polymer film, a manifold, and an adhesive cover. A method of manufacturing the dressing may comprise providing a first layer, such as the gel layer, on a substrate, perforating the first layer on the substrate to create a plurality of apertures in the first layer, and creating an index of the plurality of apertures in the first layer. A laser can be calibrated based on the index. A second layer, such as the polymer film, may be coupled to the first layer, and a plurality of slots can be cut in the second layer with the laser. Each of the slots can be cut through one of the apertures in the first layer based on the index.

Abstract: A flexible dressing for applying to a tissue site for determining the extent of debridement required to remove non-viable tissue is disclosed. Some embodiments of the dressing may be in the form of a multi-layer drape having an integrated tissue viability indicator system. Some embodiments may also include a system of shapes or a grid pattern printed or embossed on a surface of the drape for providing guidance during an ensuing debridement or amputation procedure.