Patents Issued in July 9, 2020
  • Publication number: 20200214539
    Abstract: The present technology relates to an endoscope that makes it possible to acquire a high-resolution medical image with low power consumption. The endoscope includes a camera head including: a first sensor having pixels of a first number of pixels, the first sensor being configured to receive green (G) light that is light with a G wavelength band; and a second sensor having pixels of a second number of pixels smaller than the first number of pixels, the second sensor being configured to receive light different from the G light. The present technology is applicable to, for example, an endoscopic surgery system with which surgery is performed while a medical image captured by the endoscope is viewed.
    Type: Application
    Filed: May 1, 2018
    Publication date: July 9, 2020
    Applicant: Sony Corporation
    Inventors: Yasuaki TAKAHASHI, Kenji TAKAHASHI, Takeshi MIYAI
  • Publication number: 20200214540
    Abstract: An endoscope includes: an imager; a transmission path configured to connect a controller and the imager with each other; a superimposed signal generating circuit configured to generate, as a superimposed signal, a signal obtained by associating High and Low of a pulsed data signal with a change in a pulse width of a pulsed reference clock signal; a parallel-serial converter circuit configured to perform parallel-serial conversion on the imaging signal; a PLL circuit configured to generate a multiplied clock signal; a restoring circuit configured to restore, based on the superimposed signal and the multiplied clock signal, the reference clock signal and the data signal contained in the superimposed signal; and a timing generating circuit configured to generate, based on the reference clock signal and the data signal, a drive signal for driving the imager.
    Type: Application
    Filed: March 23, 2020
    Publication date: July 9, 2020
    Applicant: OLYMPUS CORPORATION
    Inventor: Takanori TANAKA
  • Publication number: 20200214541
    Abstract: Sub-diffraction endoscopic modal imaging systems and methods are disclosed herein. A single multi-mode fiber endoscope incorporated into a modal imaging system can facilitate the imaging of inner portions of a patient's body at a quantum-limited resolution. One method of sub-diffraction endoscopic modal imaging includes collecting incoming radiation with a multi-mode fiber, separating the output into multiple modes, and measuring an energy level of each mode to construct an image of the received incoming radiation.
    Type: Application
    Filed: January 8, 2019
    Publication date: July 9, 2020
    Inventors: Lisa Lust, Mary Salit
  • Publication number: 20200214542
    Abstract: A baby endoscope which forms a medical device includes: a rotary member; an exterior member which rotatably holds the rotary member about a predetermined rotation axis, houses the rotary member in the exterior member, and has a surface which is brought into contact with a portion of an outer peripheral surface of an operation section of a mother endoscope on an outer peripheral portion; and a bending operation lever mounted on the rotary member, and is disposed within a width of the exterior member in a direction of the rotation axis when the exterior member is viewed in a direction orthogonal to the rotation axis.
    Type: Application
    Filed: March 18, 2020
    Publication date: July 9, 2020
    Applicant: OLYMPUS CORPORATION
    Inventors: Takuto YOSHINAGA, Chikayoshi MEGURO, Tatsuhiko SUZUKI
  • Publication number: 20200214543
    Abstract: An endoscope assembly comprising a handle incorporating a liquid reservoir and injection system, a cannula attaching to the handle, and a distally attached miniature imaging head. The imaging head is a transparent tubular shaped body having an essentially closed proximal end, and a tubular wall extending from the closed proximal end to the distal open end of the body. An optical source is attached to the closed proximal end, and its emitted illumination directed into the tubular wall of the body, such that said illumination is partially internally reflected within the tubular wall and is emitted both radially and from the distal open end. The optical source is disposed radially inwards of the outer dimensions of the tubular shaped body. Alternatively, the optical source can be positioned back-to-back with the camera chip. A system is provided for cell collection from the region in which the endoscope is operating.
    Type: Application
    Filed: September 12, 2018
    Publication date: July 9, 2020
    Inventor: ASAF BEN-ARYE
  • Publication number: 20200214544
    Abstract: Provided is an endoscope that can easily perform the attachment and detachment work of a proximal end side of a wire with respect to a slider. An endoscope includes a base member (98) that forms a slider housing space (150) that is independent of an internal space of an operating part (22), an opening part (94) that is provided at a proximal end of a wire channel (62) and delivers the proximal end side of the wire (60) to a slider housing space (150), a slider (96) that is disposed in the slider housing space (150) and moves in a longitudinal direction of the operating part (22) depending on the operation of an erection operating lever (20) so as to be movable forward and backward, an engaged part (152) that is provided in the slider (96) and recessed toward a lateral side orthogonal to a movement direction of the slider (96), and an engaging member (154) that is provided at the proximal end of the wire (60) and is pushed into and engageable with the engaged part (152) from the lateral side.
    Type: Application
    Filed: March 23, 2020
    Publication date: July 9, 2020
    Applicant: FUJIFILM Corporation
    Inventor: Takashi HARADA
  • Publication number: 20200214545
    Abstract: A binocular image capture device includes a plurality of stacked circuit boards, a front-facing dual image sensor mounted to a first circuit board of the plurality of stacked circuit boards, and signal conditioning electronics mounted to one or more of the plurality of stacked circuit boards and coupled to receive electrical signals generated by the dual image sensor. The dual image sensor is enclosed in a hermetic housing. In some examples, the hermetic housing may be formed by the first circuit board, a transition ring secured to the first circuit board, and an optics mount secured to the transition ring. In some examples, the hermetic housing may be formed using materials having matching coefficients of thermal expansion. In some examples, the binocular image capture device is enclosed by a shaft, the plurality of stacked circuit boards being stacked along a length of the shaft.
    Type: Application
    Filed: February 11, 2020
    Publication date: July 9, 2020
    Inventors: Viraj A. Patwardhan, John A Barton, Mathew Clopp, John E. Sell
  • Publication number: 20200214546
    Abstract: Methods and devices for visualizing and accessing a region inside a body are described. One embodiment of a device includes a working catheter which slides along an open track in a visualization catheter. The visualization catheter is inserted into the body to locate a region of the body with the aid of the visualization element. The working catheter then slides along the track to reach the region, and a working element is inserted through the working catheter to access the region, again with the aid of the visualization element. The methods and devices may also be used to access a variety of internal cavities, soft tissues and organs, and the mediastinal space.
    Type: Application
    Filed: December 19, 2019
    Publication date: July 9, 2020
    Inventors: Kabir GAMBHIR, Thomas A. RITTER
  • Publication number: 20200214547
    Abstract: An imaging unit acquires a white light image by imaging an observation target being illuminated with white light, and acquires a specific light image by imaging the observation target being illuminated with specific light. A light source control unit controls the number of light emission frames of the white light and the number of light emission frames of the specific light in one light emission cycle according to at least one of a moving speed of the imaging unit, zoom information, or a light emission amount.
    Type: Application
    Filed: March 19, 2020
    Publication date: July 9, 2020
    Applicant: FUJIFILM Corporation
    Inventor: Tatsuya AOYAMA
  • Publication number: 20200214548
    Abstract: An arrangement, and associated method, for cleaning and disinfecting an endoscope having an internal channel accessible via an opening. The arrangement includes: a support structure; at least one tray including at least one fixture arranged to maintain the endoscope in the desired position within the tray; a rack arranged to support the tray; a control unit arranged to control and operate the arrangement; a user interface connected to the control unit and arranged to make it possible for an operator to indicate the type of endoscope arranged in the tray; an optical device connected to the control unit and configured to confirm the type of endoscope arranged in the tray; a robotic device operated by the control unit and arranged to clean the at least one channel in the endoscope arranged in the tray; and a disinfector device arranged to enclose the tray and disinfect the endoscope.
    Type: Application
    Filed: September 15, 2017
    Publication date: July 9, 2020
    Inventor: Michael LARSSON
  • Publication number: 20200214549
    Abstract: Cannula and scope cleaning apparatus and associated methods of use are provided which allow for the clearing/cleaning of a cannula and cleaning of a viewing scope during a medical procedure, wherein the apparatus can be configured such that the viewing scope need not be removed from within the cannula in order for debris and/or fogging to be removed from a lens portion of the scope. In particular embodiments, the cannula and scope cleaning apparatus can be deformable, having an adjustable lumen therein such that when the apparatus can be disposed within a cannula, viewing scopes having various outside diameter sizes can be slidably introduced and stabilized within a cannula.
    Type: Application
    Filed: March 16, 2020
    Publication date: July 9, 2020
    Inventors: Ronald Hurst, Dan Garr
  • Publication number: 20200214550
    Abstract: Anti-fogging system for an endoscope including an endoscope having an outer housing, an imaging arrangement, and a distal window. A filter lens is located at the distal window, with the filter lens allowing a first portion of electromagnetic light to pass therethrough while absorbing a second portion of electromagnetic light in order to heat the filter lens.
    Type: Application
    Filed: January 17, 2020
    Publication date: July 9, 2020
    Applicant: Stryker Corporation
    Inventors: David B. BENNETT, Benjamin H. FEINGOLD, John SHEN
  • Publication number: 20200214551
    Abstract: The invention relates to a method for determining the likelihood of being at or beyond a certain rate and/or risk of visual field progression (VFP) of a user, comprising the following steps: an installing step (S100) comprising placing or implanting a continuous-wear sensor on or in an eye of a user; a measuring step (S101) comprising measuring ocular biomechanical properties (OBP) through the continuous-wear sensor placed on or implanted in the eye, with said measurement comprising repeated data capture at regular time intervals; a recording step (S102) comprising recording the user's ocular biomechanical properties in the form of at least one OBP time series plot in a recorder; a processing step (S103) wherein at least one of a plurality of OBP parameters are extracted from the at least one recorded OBP time series plot; a calculation step (S104) wherein the at least one of a plurality of OBP parameters are associated to VFP; a determining step (S105) wherein one determines whether the visual field progress
    Type: Application
    Filed: June 14, 2017
    Publication date: July 9, 2020
    Inventors: Mario Schlund, Thierry Varidel, Raphael Fritschi, Carlos Gustavo De Moraes
  • Publication number: 20200214552
    Abstract: The present disclosure relates to a visual field testing method, system, and testing apparatus based on head-mounted testing equipment (02). The method includes: transmitting, by the testing apparatus in electronic equipment (01), a start notification for starting monitoring of a movement trajectory of a pupil of a current eye to be tested to an eye movement tracking system (03) after receiving a start test instruction transmitted from a controller; receiving, by the testing apparatus, movement state information of the pupil (202) that is transmitted from the eye movement tracking system (03); and determining, by the testing apparatus, the movement trajectory (203) of the pupil according to the movement state information, wherein the controller is a component that is associated with the head-mounted testing equipment (02) and communicatively connected to the testing apparatus of the electronic equipment (01). The method can reduce the testing complexity and may also improve the testing accuracy and comfort.
    Type: Application
    Filed: June 1, 2018
    Publication date: July 9, 2020
    Inventors: Yi Zhen, Weihong Zheng, Cong Zhang
  • Publication number: 20200214553
    Abstract: The invention relates to a method for obtaining a visual field map of an observer, particularly a perimetry method, wherein a plurality of test locations in front of the observer is provided, at each test location of a subset of said plurality a respective perceived sensitivity threshold is measured, wherein at least one light signal is provided at the respective test location, and wherein it is monitored whether said observer observes said at least one light signal, and wherein for each test location a respective estimate of the perceived sensitivity threshold is derived from the previously measured perceived sensitivity thresholds of said subset, and wherein said light signal is provided at a light intensity value derived from the estimate of the perceived sensitivity threshold of said respective test location.
    Type: Application
    Filed: September 18, 2018
    Publication date: July 9, 2020
    Applicant: UNIVERSITÄT BERN
    Inventors: Serife Seda KUCUR, Raphael SZNITMAN
  • Publication number: 20200214554
    Abstract: A convolutional neural network model distinguishes eyelash images, break-up area images, non-break-up images, sclera images and eyelid images corresponding to a first prediction score, a second prediction score, a third prediction score, a fourth prediction score and a fifth prediction score to respectively produce a first label, a second label, a third label, a fourth label and a fifth label, thereby a break-up area can be detected in a tear film image and a tear film break-up time can be quantized for detection.
    Type: Application
    Filed: January 4, 2019
    Publication date: July 9, 2020
    Inventors: TAI-YUAN SU, ZI-YUAN LIU, DUAN-YU CHEN
  • Publication number: 20200214555
    Abstract: The object of the present invention is to develop an ophthalmologic microscope of a new method that increases the degree of freedom in the optical design in the Galilean ophthalmologic microscope provided with an OCT optical system. The present invention provides an ophthalmologic microscope 1 comprising; an illuminating optical system 300, an observation optical system 400; an objective lens 2; and an OCT optical system 500, characterized in that the optical axis 0-500 of the OCT optical system does not penetrate through the objective lens 2, it comprises objective lens for OCT 507 through which the optical axis 0-500 of the OCT optical system penetrates, and deflection optical elements 503a, 503b for scanning of the OCT optical system and the objective lens for OCT 507 are in a substantially optically conjugate positional relation.
    Type: Application
    Filed: May 2, 2018
    Publication date: July 9, 2020
    Applicant: Topcon Corporation
    Inventors: Yasufumi FUKUMA, Kazuhiro OOMORI
  • Publication number: 20200214556
    Abstract: An ophthalmological device of some embodiment examples includes a memory, detecting processor, identifying processor, transforming processor, and composing processor. The memory stores a plurality of angiograms acquired by applying optical coherence tomography to an eye fundus. The detecting processor is configured to detect a feature point from each of the angiograms. The identifying processor is configured to identify a plurality of feature point groups from among a plurality of feature points detected from the angiograms. Each feature point group corresponds to a same site of the eye fundus. The transforming processor is configured to transform at least part of the angiograms based on the feature point groups. The composing processor is configured to compose two or more angiograms of the angiograms at least part of which has been transformed, based on the feature point groups.
    Type: Application
    Filed: May 17, 2018
    Publication date: July 9, 2020
    Applicant: TOPCON CORPORATION
    Inventors: Hiroyuki AOKI, Taiki AIMI
  • Publication number: 20200214557
    Abstract: An ophthalmologic apparatus, includes: a first concave mirror and a second concave mirror having a concave surface-shaped first reflective surface and a concave surface-shaped second reflective surface; an SLO optical system configured to project light from an SLO light source onto a subject's eye via the first concave mirror and the second concave mirror, and to detect returning light from the subject's eye; a first optical scanner configured to deflect the light from the SLO light source to guide the light to the first reflective surface; a second optical scanner configured to deflect light reflected by the first reflective surface to guide the light to the second reflective surface; an OCT optical system including a third optical scanner, and configured to split light from an OCT light source into measurement light and reference light, to project the measurement light deflected by the third optical scanner onto the subject's eye, and to detect interference light between returning light of the measurement l
    Type: Application
    Filed: December 31, 2019
    Publication date: July 9, 2020
    Applicant: TOPCON CORPORATION
    Inventors: Ryoichi HIROSE, Tatsuo YAMAGUCHI
  • Publication number: 20200214558
    Abstract: The disclosure provides an optical component for retinal imaging including: a light source module, a beam splitter, an imaging module, a scanning module, and a flat field objective lens. The flat field objective lens is between the scanning module and a detection position, the light source module is configured to emit, to the beam splitter, a detection light for illuminating a fundus, the detection light being guided by the beam splitter to the scanning module and emitted to the detection position through the scanning module and the flat field objective lens, reflected light from the detection position can pass through the scanning module and reaches the beam splitter, and is guided by the beam splitter to the imaging module. The scanning module includes a scanning objective lens reciprocally movable along its central axis, and the flat field objective lens is reciprocally movable along its central axis.
    Type: Application
    Filed: December 14, 2017
    Publication date: July 9, 2020
    Inventors: Qingyang WANG, Guohua SHI
  • Publication number: 20200214559
    Abstract: A faceguard is configured for measuring a human eye muscle movement response. The faceguard is configured for protecting at least one part of a human face and has an aperture for human vision through the faceguard. The faceguard comprises an eye sensor, a head orientation sensor, and an electronic circuit. The eye sensor comprises a video camera and is configured for measuring eyeball movement, pupil size, and/or eyelid movement. The head orientation sensor senses pitch and/or yaw of a person's head. The electronic circuit is responsive to the eye sensor and the head orientation sensor.
    Type: Application
    Filed: February 28, 2020
    Publication date: July 9, 2020
    Inventors: Wesley W.O. Krueger, Trouper Krueger
  • Publication number: 20200214560
    Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.
    Type: Application
    Filed: December 6, 2019
    Publication date: July 9, 2020
    Inventors: Charles Raymond Kalina, JR., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
  • Publication number: 20200214561
    Abstract: A gonioscopic attachment can attach to a gonioscope and can include atraumatic retention elements that are configured to engage an eye to retain the gonioscope relative to the eye. The gonioscopic attachment can be configured to position the gonioscope so that at least a portion of the concave distal surface of the gonioscopic optical element is spaced apart from the eye, and/or so that the curvature of the distal surface is angularly offset from the curvature of the eye. The gonioscope can include a fixation point configured to be visible to the subject when the gonioscope is positioned on the eye. In some embodiments, the retention elements can be incorporated directly into the gonioscope. A coupling mechanism can couple the gonioscope to a lid speculum. The gonioscope can include a light pipe, which can be configured to directly light into the eye.
    Type: Application
    Filed: December 9, 2019
    Publication date: July 9, 2020
    Inventors: Charles Raymond Kalina, JR., Thomas W. Burns, Chris Calcaterra, Edward Collins, Timothy McCauley, David S. Haffner, Steven M. Henderson
  • Publication number: 20200214562
    Abstract: In an ophthalmic imaging system an image imaged by an imaging section for a right eye is formed as an imaging image on a display, and then displayed through a right-eye optical unit and a reflection member. An image imaged by an imaging section for a left eye is formed as an imaging image on a display, and then displayed through an optical unit and the reflection member. This thereby enables the object to be visually inspected as a three-dimensional image by the observer viewing the right-eye imaging image and the left-eye imaging image, which differ from each other according to the parallax therebetween, by viewing the respective images through right and left eyes.
    Type: Application
    Filed: March 19, 2020
    Publication date: July 9, 2020
    Applicant: NIKON CORPORATION
    Inventors: Tomohiro KAWASAKI, Masahiro MIZUTA, Ryoichi SATAKA, Toshiyuki NAMIKAWA
  • Publication number: 20200214563
    Abstract: A machine-implemented method including obtaining physiological signal data for a living being and performing a first analysis of the physiological signal data at a processing device local to the living being and remote from a central processing device. The method further includes transmitting from the processing device data associated with the analysis to the central processing device and performing at the central processing device a second analysis of the data associated with the first analysis. The method further includes displaying the data associated with the second analysis. The method can also include interaction between the processing device local to the living being and the central processing device. The method can also include distributing monitoring and analysis between an ambulatory and a centralized subsystem.
    Type: Application
    Filed: March 19, 2020
    Publication date: July 9, 2020
    Inventor: Dongping Lin
  • Publication number: 20200214564
    Abstract: The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.
    Type: Application
    Filed: October 9, 2019
    Publication date: July 9, 2020
    Inventors: Amy M. Heintz, Krenar Shqau, Ramanathan Lalgudi, Patrick Ganzer, Ming Ming Zhang, Jacob Lilly
  • Publication number: 20200214565
    Abstract: Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are disclosed. In an embodiment, a method for transmitting data between a first communication device associated with an analyte sensor and a second communication device configured to provide user access to sensor-related information comprises: activating a transceiver of a first communication device associated with an analyte sensor at a first time; and establishing a two-way communication channel with the second communication device; wherein the activating comprises waking the transceiver from a low power sleep mode using a forced wakeup from the second communication device.
    Type: Application
    Filed: March 18, 2020
    Publication date: July 9, 2020
    Inventors: Thomas Miller, Mark Dervaes, Phong Lieu, Peter C. Simpson, Shawn Larvenz, Jacob S. Leach, Sebastian Bohm
  • Publication number: 20200214566
    Abstract: Systems and methods are described for configuring and using displays, speakers, or other output devices positioned by an article of clothing or other such structure wearable by a healthcare recipient, for example, in a clinic or residential care facility.
    Type: Application
    Filed: March 23, 2020
    Publication date: July 9, 2020
    Inventors: Paul G. Allen, Edward S. Boyden, Mahalaxmi Gita Bangera, W. Daniel Hillis, Roderick A. Hyde, Muriel Y. Ishikawa, Edward K.Y. Jung, Eric C. Leuthardt, Dennis J. Rivet, Michael A. Smith, Elizabeth A. Sweeney, Lowell L. Wood, JR., Victoria Y.H. Wood
  • Publication number: 20200214567
    Abstract: A skull-mounted drug and pressure sensor (SOS), a smart pump (ISP) electrically coupled to the SOS and a drug delivery and communications catheter communicating the SOS with the ISP are combined for a first embodiment. A skull-mounted (SOS), a metronomic biofeedback pump (MBP) electrically coupled to the SOS and a drug delivery and communications catheter having a sending and receiving optical fiber communicating the SOS with the MBP are combined for a second embodiment. A third embodiment combines a (SOS), an implantable power and communication unit (PCU) electrically coupled to the SOS, and a drug delivery and communications catheter for communicating the SOS with the PCU and for communicating the exterior source of the drug to the SOS. A fourth embodiment combines a ventricular catheter with a CSF accessible chamber and drug delivery port; and an implantable stand-alone skull-mounted drug and pressure sensor (SPS).
    Type: Application
    Filed: March 6, 2020
    Publication date: July 9, 2020
    Applicant: Cognos Therapeutics Inc.
    Inventors: Yehoshua Shachar, Thomas Chen, Thomas J. Lobl, Jeffrey A. Brydle, Juan R. Gonzalez, Virote Indravudh, Christian Merot, Allan R. Schwartz, Chad Srisathapat
  • Publication number: 20200214568
    Abstract: An imaging assembly, system and method for automated multimodal imaging of biological tissue is provided. It finds particular application, although in no way exclusively, in the medical imaging of breast tissue. An optical 3D scanner is included to determine the shape of the surface of both breasts and output a plurality of 3D coordinates thereof. An X-ray generator is included for sequentially radiating X-rays at a plurality of angles, through the tissue, toward an X-ray detector positioned below the patient and thus the breasts. An articulated arm holding an ultrasound transducer at an end thereof automatically moves the ultrasound transducer along a path defined by the obtained 3D coordinates for ultrasound imaging of the breasts while maintaining the transducer in contact with the surface at an orientation required for ultrasound imaging.
    Type: Application
    Filed: September 21, 2018
    Publication date: July 9, 2020
    Inventors: Christopher Leonard Vaughan, Roland Victor Baasch
  • Publication number: 20200214569
    Abstract: Disclosed is a transcranial magnetic stimulation (TMS) stimulation navigation method comprising the steps of: acquiring a stimulation target point in the brain of a subject to which an electrical stimulus is to be applied; acquiring data on the spatial distribution of a magnetic vector potential of a coil for a TMS procedure; acquiring, from the spatial distribution, at least one parameter for acquiring an optimal stimulation condition for the stimulation target point; and by using the acquired parameter, calculating a position and direction of the coil satisfying the optimal stimulation condition for the stimulation target point.
    Type: Application
    Filed: March 10, 2020
    Publication date: July 9, 2020
    Applicant: NEUROPHET INC.
    Inventor: Dong Hyeon KIM
  • Publication number: 20200214570
    Abstract: Disclosed is a method for generating a three-dimensional brain map, comprising the steps of: acquiring a brain magnetic resonance imaging (MRI) image of an object; segmenting the brain MRI image into a plurality of regions; generating a three-dimensional brain image of the object including the plurality of regions by using the segmented brain MRI image; and generating a three-dimensional brain map of the object capable of simulating a process of transferring electrical stimulation to the brain of the object based on properties of each of the plurality of regions included in the three-dimensional brain image, wherein the step of segmenting includes the step of acquiring a segmented brain MRI image of the object by inputting a brain MRI image of the object into a model learned by using a plurality of processed brain MRI images.
    Type: Application
    Filed: March 10, 2020
    Publication date: July 9, 2020
    Applicant: NEUROPHET INC.
    Inventor: Dong Hyeon KIM
  • Publication number: 20200214571
    Abstract: Presented herein is a multichannel imaging system capable of detecting and distinguishing multiple fluorescent light sources simultaneously. Also described herein are methods of using the system to image disease or cellular abnormalities, e.g., for diagnostic and/or intraoperative purposes.
    Type: Application
    Filed: February 11, 2020
    Publication date: July 9, 2020
    Inventors: Michelle S. Bradbury, Ulrich Wiesner, Richard J.C. Meester, Snehal G. Patel, Nadeem R. Abu-Rustum, Mohan Pauliah
  • Publication number: 20200214572
    Abstract: A device for carrying out mirror therapy includes: a camera for filming a healthy limb of a patient, a work surface on which the patient positions his healthy limb or affected limb, a screen for displaying the image of the healthy limb which is positioned on the work surface and which is filmed by the camera, the screen preventing the patient from directly seeing his healthy limb or affected limb on the work surface, and a support structure which is connected to the work surface and on which the screen and the camera are mounted. The device has a mirror fixed behind the screen. The camera films the healthy limb reflected in the mirror, and the image displayed by the screen is a reflection of the healthy limb in the mirror.
    Type: Application
    Filed: September 10, 2018
    Publication date: July 9, 2020
    Inventors: Nicolas FOURNIER, Davy Christophe LUNEAU
  • Publication number: 20200214573
    Abstract: A system for producing surface temperature estimations of a tissue surface is provided. A first optical assembly receives infrared light emitted from multiple tissue surface areas. A fiber receives the infrared light from the first optical assembly, and a sensor that is optically coupled to the fiber proximal end produces a signal that correlates to an average temperature of each of the multiple tissue surface areas.
    Type: Application
    Filed: March 3, 2020
    Publication date: July 9, 2020
    Inventors: John T. Garibotto, Steven R. Auger, R. Maxwell Flaherty, J. Christopher Flaherty
  • Publication number: 20200214574
    Abstract: An apparatus for dental confocal imaging comprises an illumination module for generating an array of light beams, an optics system for confocal focusing of the array of light beams and a probe head with a light-guiding part having an entrance face and an exit face. The illumination module, the optics system and the probe head are arranged such that the array of light beams from the illumination module passes through the optics system, enters the light-guiding part via the entrance face and exits the light-guiding part via the exit face. The optics system is configured such that, after having passed through the optics system, the outermost marginal rays of the outermost light beams with respect to the optical axis of the optics system are parallel or divergent to the optical axis.
    Type: Application
    Filed: March 16, 2020
    Publication date: July 9, 2020
    Inventors: Yossef Atiya, Tal Verker, Nir Makmel
  • Publication number: 20200214575
    Abstract: Heart rates and beat lengths of a subject can be extracted from videos of the subject by measuring subtle head motion caused by the Newtonian reaction to the influx of blood at each beat. Embodiments track features on the video images of the subject's head and perform principal component analysis (PCA) to decompose the feature location-time series into a set of component motions. The method or system then selects a component that best corresponds to heartbeats based on its temporal frequency spectrum. Finally, the motion projected to this component is analyzed and peaks of the location-time series are identified, which correspond to heartbeats. Pulse rate measurements or heart rate measurements of the subject are output.
    Type: Application
    Filed: March 19, 2020
    Publication date: July 9, 2020
    Inventors: Guha Balakrishnan, John V. Guttag, Frederic Durand, Ph.D.
  • Publication number: 20200214576
    Abstract: Embodiments of the present disclosure relate to heart sound measurements using mobile devices. In an embodiment, a medical system for monitoring heart sounds of a subject comprises a medical device configured to obtain, during a first sampling interval, a first physiological signal. The medical system further comprises a mobile device comprising an accelerator, wherein the accelerator is configured to obtain, during a second sampling interval, a second physiological signal. And, the medical system comprises an analysis component configured to extract heart sounds data from the second physiological signal.
    Type: Application
    Filed: January 2, 2020
    Publication date: July 9, 2020
    Inventors: Jonathan B. Shute, Kyle H. Srivastava, Pramodsingh H. Thakur, Keith R. Maile
  • Publication number: 20200214577
    Abstract: A cuff-type monitoring device, for collecting cardiovascular data relating to an individual user, comprising a control unit housing and a cuff assembly coupled or attached to the control unit housing, the cuff assembly comprising an inner layer, an inflatable bladder, a cuff holder, forming an structural resilient armature of the cuff assembly, an intermediate sheet, an outer band, wherein the cuff assembly is configured, in use, to surround a upper limb of the individual, with the inner layer in contact with the upper limb, wherein control unit housing comprises at least a pump configured to inflate the inflatable bladder, wherein the intermediate sheet is made in an inextensible, i.e. non-stretchable, fabric and there is provided a border joint or seam at least on three sides on a peripheral border of the inflatable bladder, the border joint joining and securing together the inner layer, the inflatable bladder, the intermediate sheet, and the an outer band.
    Type: Application
    Filed: December 18, 2019
    Publication date: July 9, 2020
    Applicant: WITHINGS
    Inventors: Jean-Louis WANG, Xianzhi ZHANG, Virginie VISSAC, Pierre-Antoine CUNIASSE, Benoit TUCOULAT, Mélanie ALSBERGHE-PATEL
  • Publication number: 20200214578
    Abstract: A cuff-type monitoring device, for collecting cardiovascular data relating to an individual user, comprising a control unit housing including a pump, a cuff assembly including a resilient cuff holder and an interface member arranged at the control unit housing, provided integral with the control unit housing or as a separate part, wherein there is provided at least a pneumatic coupling and an electrical coupling through the interface member, for coupling the cuff assembly to the control unit housing, wherein the resilient cuff holder comprises two retaining members, the interface member comprising two complementary retaining members, configured to be snap-fit with the retaining members, and assembly method to assemble the device.
    Type: Application
    Filed: January 3, 2020
    Publication date: July 9, 2020
    Applicant: WITHINGS
    Inventors: Xianzhi ZHANG, Jean-Louis WANG, Virginie VISSAC, Pierre-Antoine CUNIASSE, Benoît TUCOULAT, Mélanie ALSBERGHE-PATEL
  • Publication number: 20200214579
    Abstract: An example embodiment includes a blood pressure monitor system configured to continuously monitor blood pressure. The blood pressure monitor system includes a housing, a sensor arranged in a first side of the housing, at least one light emitting diode arranged in the first side of the housing, a barrier coupled to the housing and arranged between the sensor and the at least one light emitting diode, wherein the barrier is opaque, and a processor in communication with the sensor, the processor configured to continuously determine a blood pressure based on a reflected light.
    Type: Application
    Filed: March 20, 2020
    Publication date: July 9, 2020
    Inventors: Shane Phillips, Mohamed Ali
  • Publication number: 20200214580
    Abstract: The invention relates to catheters and apparatuses for combined imaging and obtaining pressure measurement in a vessel having a stenosis. The imaging can be an optical imaging technology or ultrasound imaging. The apparatus can include a combined probe comprising an imaging channel and a pressure measurement channel, and a signal processor in communication with the imaging channel and the pressure measurement channel.
    Type: Application
    Filed: January 3, 2019
    Publication date: July 9, 2020
    Applicant: KOTL LLC
    Inventors: Wei Kang, Chenyang Xu
  • Publication number: 20200214581
    Abstract: Systems and methods for treatment of neurological conditions using aTBS in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including generating a personalized accelerated theta burst stimulation (aTBS) target representing a location in a patient's brain related to a neurological condition, placing a TMS device relative to the patient's brain such that the focus of the magnetic field is over the aTBS target, applying TMS to the aTBS target according to an aTBS protocol to the brain using the TMS device to alleviate the neurological condition.
    Type: Application
    Filed: March 13, 2020
    Publication date: July 9, 2020
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Nolan Williams, Keith Sudheimer
  • Publication number: 20200214582
    Abstract: A system for vital sign measuring of a patient, comprising: a first sensor removably attachable with a first body portion of the patient and configured to measure, when in operable position, a vital sign of the patient; at least one additional sensor removably attachable with a second body portion of the patient and configured to measure, when in operable position, a vital sign of the patient; and a processor configured to provide data descriptive of a level of correspondence between measurements of the vital signs provided by the first sensor and the at least one additional sensor.
    Type: Application
    Filed: January 6, 2020
    Publication date: July 9, 2020
    Inventors: Nimrod ADI, Gil ZOIZNER, Jonathan RUBIN
  • Publication number: 20200214583
    Abstract: An interface structure for a biological environment including at least one composite electrical impulse generating layer comprising a matrix phase of a piezo polymer material, a first dispersed phase of piezo nanocrystals, and second dispersed phase of carbon nanotubes, the first and second dispersed phase presented through the matrix phase. The piezo polymer material and piezo nanocrystal convert mechanical motion into electrical impulses and accept electrons to charge the composite impulse generating layer. The carbon nanotubes provide pathways for distribution of the electrical impulses to a surface of the composite impulse generating layer contacting the biological environment. The carbon nanotubes further provide for the delivery of the byproducts of the free radical degradation from the biological environment to both piezo-nanocrystals and piezo-polymer.
    Type: Application
    Filed: March 11, 2020
    Publication date: July 9, 2020
    Inventors: Maxim Signaevsky, Igor Yehuda Yaroslavsky
  • Publication number: 20200214584
    Abstract: Systems, devices, methods, and techniques relating to generating and presenting information related to heart rate data. In one aspect, a system includes a monitoring device configured to obtain physiological data for a living being and to generate annotation data based on the physiological data for a total time period, a processing system configured to obtain the annotation data via a communication channel from the monitoring device and to generate for display based on the annotation data a daily patient report that includes, a chart showing summary statistical data for a proportion of a total monitored time period spent in cardiac arrhythmia for each of a plurality of days and summary statistical data for a proportion of the total monitored time period not spent in cardiac arrhythmia for each of the plurality of days.
    Type: Application
    Filed: December 11, 2019
    Publication date: July 9, 2020
    Applicant: Braemar Manufacturing, LLC
    Inventors: Anna McNamara, Jonathan Newbrough, Charles Gropper, Aaron Goldmuntz, Yachuan Pu
  • Publication number: 20200214585
    Abstract: Cardiac activation wavefronts can be computed as one or more stream paths or stream lines from electrophysiological data collected by a multi-electrode catheter. In embodiments of the disclosure, the stream path or stream line is computed by identifying a first activating bipole from amongst the electrodes and then iteratively identifying successively later-activating, neighboring bipoles. The process can be repeated for additional bipoles and/or additional locations of the multi-electrode catheter within the subject's heart. In additional embodiments of the disclosure, stream paths or stream lines are computed from a conduction velocity vector field or mesh, distributed over a cardiac geometry, by identifying the path of one or more seed points through the conduction velocity vector field. The stream paths and/or stream lines can be graphically output, such as on a three-dimensional cardiac geometry model.
    Type: Application
    Filed: December 9, 2019
    Publication date: July 9, 2020
    Inventors: Jan O. Mangual-Soto, Federico Calore
  • Publication number: 20200214586
    Abstract: The present invention relates to a method for generating a sensorial stimulus using electroencephalographic data acquired from a subject, the method comprising the following steps: receiving electroencephalographic data comprising at least two electroencephalographic signals measured simultaneously from at least two electroencephalogram channels; calculating an alpha phase neuromarker on consecutive epochs of the electroencephalographic data, the alpha phase neuromarker being representative of at least the phase coherence between alpha waves recorded from the at least two electroencephalogram channels; and generating a sensorial stimulus representing alpha phase neuromarker using an output generator.
    Type: Application
    Filed: September 18, 2018
    Publication date: July 9, 2020
    Applicant: CYREBRO TECHNOLOGIES
    Inventors: Quentin BARTHELEMY, Louis MAYAUD
  • Publication number: 20200214587
    Abstract: Systems and methods are provided for detecting and analyzing changes in a body. A system includes an electric field generator, an external sensor device, a quadrature demodulator, and a controller. The electric field generator is configured to generate an electric field that associates with a body. The external sensor device sends information to the electric field generator and is configured to detect a physical change in the body in the electric field, where the physical change causes a frequency change of the electric field. The quadrature demodulator receives the electric field from the electric field generator and is configured to detect the frequency change of the electric field and to produce a detected response. The controller, coupled to the electric field generator, is configured to output a frequency control signal to the electric field generator and to modify the frequency of the electric field by adjusting the frequency control signal.
    Type: Application
    Filed: March 19, 2020
    Publication date: July 9, 2020
    Inventors: John B. LANGLEY, II, Guy MCILROY
  • Publication number: 20200214588
    Abstract: An electrophysiology map, for example a map of arrhythmic substrate, can be generated by acquiring both geometry information and electrophysiology information pertaining to an anatomical region, and associating the acquired geometry and electrophysiology information as a plurality of electrophysiology data points. A user can select two (or more) electrophysiological characteristics for display, and can further elect to apply various filters to the selected electrophysiological characteristics. The user can also define various relationships (e.g., Boolean ANDS, ORs, and the like) between the selected and/or filtered characteristics. The user-selected filtering criteria can be applied to the electrophysiology data points to output various subsets thereof. These subsets can then be graphically rendered using various combinations of colorscale, monochrome scale, and iconography, for example as a three-dimensional cardiac electrophysiology model.
    Type: Application
    Filed: March 13, 2020
    Publication date: July 9, 2020
    Inventors: Wenwen Li, Erhan Erdemir, Valtino X. Afonso, Carlo Pappone, Dennis Morgan