Abstract: An absorbent article comprising at least one stretchable laminate comprising a first nonwoven, a second nonwoven, and an elastic film therebetween, wherein each of the first and second nonwovens is adhesively bonded to the film by a hot melt adhesive; wherein the film is no thicker than about 60 micrometers; wherein at least one of the nonwovens is spunbonded; wherein the laminate is activated with a minimum of about 290% applied strain and a minimum strain rate of about 850/sec; and wherein the laminate is substantially free from pinholes.

Abstract: An absorbent core for use in an absorbent article, the absorbent core including a first absorbent layer comprising a first substrate, a layer of first superabsorbent polymer particles deposited on the first substrate on a deposition area and a fibrous layer of thermoplastic adhesive material covering the layer of first superabsorbent polymer particles, and a second absorbent layer comprising a second substrate and a mixed layer comprising a mixture of second superabsorbent particles and cellulosic fibers deposited on the second substrate. The first and second absorbent layers are combined together such that at least a portion of the fibrous thermoplastic adhesive material of the first absorbent layer contacts at least a portion of the mixed layer of the second absorbent layer.

Abstract: A soiled diaper detection system having a soiled diaper detection device, one or more computer devices in communication with the diaper detection device configured to generate and process requests to the diaper detection device, and store data received from the soiled diaper detection device.

Abstract: An absorbent article has one or more fluid filter layers to inhibit electrode traces from being exposed to low volumes of fluid to reduce the number of false positives that are indicated by an RFID tag of the incontinence detection pad. An antenna inlay has a sacrificial trace portion to permit testing for proper operation of an RFID chip electrically coupled to the antenna inlay. After testing, the sacrificial trace portion is severed. A fluid barrier layer blocks fluid from reaching portions of electrode traces that are located on a backsheet outside a periphery of an absorbent core of an incontinence detection pad. The power at which an antenna transmits to wirelessly energize a passive RFID tag of an incontinence detection pad is controlled to reduce the number of false positives indicated by the RFID tag.

Abstract: A disposable absorbent article may include a chassis that includes a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet; and a leg gasketing system. The leg gasketing system may include an inner cuff and an outer cuff; the inner cuff may include an inner cuff folded edge and an inner cuff material edge and the outer cuff may include an outer cuff folded edge and an outer cuff material edge such that the web of material is folded laterally inward to form the outer cuff folded edge and folded laterally outward to form the inner cuff folded edge, and the leg gasketing system further including a leg gasketing system pocket with an opening on an inboard longitudinal edge of the leg gasketing system pocket. The disposable absorbent article also includes at least one channel in the absorbent core.

Abstract: A disposable absorbent article having a facing layer joined to a backsheet and an absorbent core disposed between the facing layer and the backsheet, is described herein. The facing layer is a composite material having a plurality of apertures extending through the facing layer.

Abstract: An absorbent article that has a reduced tendency to shift when worn. The absorbent article includes a chassis with a front waist portion, a crotch portion, and a back waist portion. Side panels or ears are attached to the front and back waist portions of the chassis, and fastening components are attached to the back ears. Anti-skid elements are added to the outside surface and/or inside surface of the front side panels or ears and/or to the inside surface of the fastening tabs, such as by applying an elastomeric strip in a substantially vertical direction. When the absorbent article is fastened to the wearer attaching the fastening components on the back ears to the front waist portion of the absorbent article, the anti-skid elements interface with the front waist portion, the front ears, and/or the wearer to exert friction and thereby reduce shifting of the fastened absorbent article.

Abstract: A diaper fastener is provided of the type having a substantially planar elastically extensible base member and three spaced hook units that have teeth operable to engage the fabric of a diaper in relevant zones thereof with the elastically extensible part stretched and operative to maintain the teeth in engagement with the diaper fabric to hold the diaper in its functional position. At least one of the hook units and generally all three are each composed of two parts that are permanently clipped together from opposite sides of the base member by inter-engaging formations. One of the parts has the hook teeth formed integral therewith and the two parts co-operate with the base member to physically locate the hook unit on the base member. Preferably, each hook unit is carried by an arm forming part of the planar base. Each hook unit has a hook part and a clamping part.

Abstract: This invention includes embodiments which disclose patient transportation devices such as toboggans or litters, which may include adjustable handle lock and positioning systems, a handle attachment and detachment system which renders the handle readily attachable and detachable to the transportation device and/or an anchor system for securing or stabilizing rescue stretchers and rescue litters when rescuing and transporting patients.

Abstract: A hinge assembly includes a first hinge member including a first outer finger defining a first aperture, the first aperture including a first circumferential tapered surface, a second hinge member including a second outer finger defining a second aperture, the second aperture including a second circumferential tapered surface, and a fastener assembly including a first hub, a second hub, and a fastener, the first hub including a circumferential tapered surface that is complimentary to the first circumferential tapered surface, and the second hub including a circumferential tapered surface that is complimentary to the second circumferential tapered surface, the fastener assembly is configured to connect the first hinge member to the second hinge member.

Abstract: There is provided a patient support that may be adjustable in height, width, length or a combination thereof. The patient support may be useable with normal sized patients or with bariatric patients. The patient support has a variety of features to enhance operability and/or functionality, including a width adjustable caster frame, width adjustable deck portions, a width adjustable headboard and an extendible foot board to provide extra length. An enhanced lift mechanism can accommodate bariatric patients and alternative functionality in achieving deck positions improves patient comfort. Various parts of the patient support including deck panels and the footboard may be removed and replaced with ease without complicated connectors.

Abstract: A mobility assistance device including a base section and an upright section. The base section is configured to be disposed under a cushion-type portion of a piece of furniture. The base section includes a first base component and a second base component, each of the first and second base components including a first portion defining a base plane and a second portion extending generally upright in a plane perpendicular to the base plane. The upright section includes an arched component configured to couple the second portions of the two base components, and a height-adjustable handle coupled to the arched component.

Abstract: A moisture control system includes a moisture control coverlet (10) and a fluid pump (18). The moisture control coverlet (10) includes a fluid pathway therein for moisture removal fluid. The fluid pump (18) is coupled to the fluid pathway for pumping fluid out of the fluid pathway by negative pressure at a fluid pump rate. The fluid pump rate can be adjustable and/or can be greater than 1 CFM.

Abstract: This invention provides a novel blending and application of technologies that creates a low cost, disposable bio-secure environment to temporarily hold, and where required to transport, patients who are suspected of having an infectious or contagious disease requiring contact isolation precautions. Upon initial presentation of such patients, health care facilities are able to hold such patients while they are initially assessed and then, if need be, transported to an appropriate biosafety level unit. The described Environmental Unit differs significantly from current products in many ways. The unique design provides a unit that is disposable and relatively inexpensive. The frame is designed to integrate with hospital stretchers and beds. The unit is large enough for a patient to sit up and allows movement of arms and legs and the ability to eat and drink while isolated on a bed.

Abstract: A rail system for a medical table includes a frame, a rail coupled to the frame and an apparatus for reacting a moment on the rail. The apparatus is operatively secured to a first position on the rail and is configured to apply a first moment on the rail to counteract a second moment applied to the rail.

Abstract: Embodiments disclosed herein relate to a garment system including at least one muscle or at least one joint activity sensor, and at least one actuator that operates responsive to sensing feedback from the at least one muscle or the at least one joint activity sensor to cause a flexible compression garment to selectively compress against or selectively relieve compression against at least one body part of a subject. Embodiments disclosed herein also relate to methods of using such garment systems.

Abstract: A magnetic conveyance system comprising a support structure having a ferromagnetic capacity and a trolley moveable upon the support structure in a plurality of directions. The trolley may include a trolley frame and at least one attractor cell disposed on the trolley frame. The at least one attractor cell may comprise a housing and at least one magnet, at least one friction reducing load spreading device, and a load transfer member disposed within the housing. The magnet may provide a magnetic attraction force between the trolley and the support structure. The friction reducing load spreading device may comprise a plurality of bearing balls circulating within a reservoir and a channel formed by the load transfer member disposed within the housing. The load transfer member may also include a bearing surface wherein a portion of the plurality of bearing balls is disposed between the bearing surface and the support structure.

Abstract: A walking assistance device includes: a base frame; two front wheels, the two front wheels on a traveling side of the base frame; and one rear wheel. An operation frame including a holding grip for an operator is height-adjustably attached to the base frame. A first axle support with the axle of the front wheels fixed is attached to the base frame, whereby the front wheels retain in contact with the ground even when the operation frame tilts. The axle of the front wheels is positioned on the traveling direction side with respect to the leading end in the traveling direction of the base frame. Providing a gap and a stopper above the rear wheel and downward pressing against the holding grip allows the stopper to come into contact with the rear wheel.

Abstract: A system and method are provided that allow a practitioner to rotate a human subject's head in three-dimensional space using a robotic arm with a head mount attached to one end, while the subject is focused on a visual target. The robotic arm is controlled by a computer system operatively coupled to the various sensors and drive motors embedded with the robotic arm.

Abstract: A sound treatment system includes an audio system for transmitting tones of predetermined frequencies through a plurality of outputs. A sound transmitting device is electrically connectable to one or more of the outputs, and includes a speaker for transmitting the tones received. The speaker is adjacent to crystal which is vibrationally responsive to the tones. A method of using the system includes generating tonal segments of predetermined duration, modulating the frequencies, and compiling these into an audio program. One or more sound transmitting devices are placed on desired locations of the body, and their inputs connected to corresponding outputs of the audio system. The generating step includes compiling selected predetermined frequencies into an audio program to generate the tonal segments, as well as modulating tones of one or more desired frequencies to generate the tonal segments.

Abstract: A foot spa tub includes a tub basin, a first magnetic drive member rotatably coupled to a drive motor, and a first casing supporting the magnetic drive member. The first casing is disposed against an exterior surface of a sidewall of the basin. A second magnetic drive member is rotatably coupled to a blade. The first and second magnetic drive members are magnetically coupled to each other so that the blade is drivingly coupled to the drive motor. A nozzle houses the second magnetic drive member and the blade. The nozzle is detachably securable to an interior surface of the sidewall by a magnetic attraction force between the first and second magnetic drive members. A method of circulating liquid in a foot tub spa is also provided.

Abstract: A child and bite resistant package having a tray and a plurality of spaced apart cavities that are formed therein is provided. A sheet material overlies the tray such that a product disposed in a cavity is enclosed and sealed therein. The sheet material includes a plurality of zones of weakening that are each disposed above a corresponding cavity. Each of the zones of weakening is formed by a plurality of microperforations that are formed in the sheet material. To access a product, the product is pushed against the lidding in the zone of weakness with sufficient force to rupture the lidding. Since the majority of the surface area above each compartment is non-rupturable, the compartments are difficult to access by a child by either hand manipulation or biting.

Abstract: The present invention relates to an adhesive label intended to be secured to a blood bag made of Polyvinyl chloride (PVC), styrenic block copolymer, polypropylene or the like, wherein the adhesive label comprises a flexible support and a layer of pressure-sensitive adhesive deposited on a surface of the support; wherein the label is noteworthy in that the support has a mineral filler rate of silica and/or calcium carbonate (CaCO3) and/or the like, of less than 50%, and wherein at 115° C., the support has an elongation greater than or equal to 2% when a test piece 1.5 cm wide of the support is suspended under tension by a weight of 375 g for ?minutes, and wherein the blood bag at 115° C. has an elongation of at least 100% when a 1.5 cm wide test piece of a blood bag is suspended under tension by a weight of 375 g for 75 minutes.

Abstract: The invention relates to an adaptor for coupling with a medical container closed by a septum, the adaptor comprising:—a gripping member (20) for securing the adaptor to the medical container,—a needle access port intended to face an outer surface of the septum,—a pierceable elastomeric piece (50) having a longitudinal axis located into the needle access port, said pierceable elastomeric piece having a recess (51) with a proximal opening and an outer wall (54) in contact with the needle access port,—attaching means for maintaining the elastomeric piece into the needle access port. The invention also relates to an assembly comprising such an adaptor and a medical container, and to the use of such an adaptor for preventing the contamination inside a medical container closed by a septum.

Abstract: A transfer device (10) for removing or transferring a medium out of or into a bottle (20) having a bottle neck (34) that can be closed by means of a closure (42), including a first adapter part (12), which can be positioned on the bottle, and a second adapter part (14), which interacts with the first adapter part, which can be displaced in the longitudinal direction of the bottle, and has a conducting element (50) for piercing the closure. After the second adapter part (14) has been displaced along the first adapter part in the direction of the closure (42) and the second adapter part has been locked, the first adapter part (12) is non-releasably fastened to or around the bottle (20).

Abstract: Disclosed herein are devices and systems for counting medication. In an aspect, the device can include a collapsible container assembly, the assembly comprising: a sheet comprising a plurality of predetermined fold lines, the plurality of predetermined fold lines configured to flex along the fold lines; wherein at least a portion of the sheet is configured to be folded along at least a portion of the fold lines into at least one predetermined shape having a predetermined volume; wherein the container assembly in a folded state is configured to releasably couple or engage a grid for collecting medication; and a grid comprising a plurality of openings, each opening configured to collect a unit of medication having a predetermined size and/or shape. Also disclosed herein are methods of using the disclosed counting devices and systems.

Abstract: A soap infused washcloth device includes a body, the body including a first side, a second side, and an edge. The first side constructed from a first material and the second side of second material. The first material includes a microfiber fabric and the second material includes an abrasive scrubbing material. The body is absorbent such that the body includes soap. The soap includes dry-soap activatable with water such that device remains dry prior to use. Preferably, soap is contained within capsule(s) contained between the first side and the second side of device. The device is removably connected to other soap infused washcloth devices in a linear fashion on a roll. A method of using a soap infused washcloth device is also described.

Abstract: A stick-shaped cosmetic contains a wax composition including (A) polyethylene wax having an average molecular weight of 600 or more and (B) carnauba wax. Additionally, the stick-shaped cosmetic includes: (C) film-forming agent; (D) volatile silicone oil agent; and (E) powder. The content of the wax composition is 4% to 13% by mass with respect to the total amount of the stick-shaped cosmetic, and the content of (A) polyethylene wax having an average molecular weight of 600 or more in the wax composition is 50% to 95% by mass with respect to the total amount of wax composition.

Abstract: A liquid foamable composition includes a cationic surfactant, a nonionic surfactant, or mixtures of these surfactants, a fatty alcohol, a silicone blend, and water. The silicone blend includes a silicone gel and a silicone powder. A foam composition, an aerosol product, and methods for improving sensory benefits to skin are also provided.

Abstract: Oral care compositions and methods for whitening teeth are provided. The oral care composition may include an orally acceptable vehicle, a whitening booster, and a source of hydrogen peroxide. The whitening booster may be dispersed in the orally acceptable vehicle. The whitening booster may include a salt of a monopersulfate, such as an alkali metal salt of the monopersulfate.

Abstract: An oral care composition, including a peroxysulfate whitening agent, a non-aqueous dispersant having a non-aqueous liquid, and a structural builder.

Abstract: Methods of making personal care compositions including microcapsules and methods of enhancing the efficacy of the microcapsules in said personal care compositions.

Abstract: The present invention relates to a multi-step process for dyeing keratin fibres, human keratin fibres such as the hair, in which said fibres are treated with: i) at least one step i) of treating said fibres using a cosmetic composition Ci) comprising a) one or more titanium salts and b) optionally one or more particular carboxylic acids; ii) at least one step of dyeing with a colouring cosmetic composition Cii) comprising c) one or more synthetic direct dyes, preferably chosen from anionic direct dyes; iii) optionally at least one step of intermediate rinsing of said fibres, said step being performed between step i) and ii) or between step ii) and i), depending on the order in which said steps i) and ii) are performed.

Abstract: A personal care composition is provided, comprising: a vehicle; a surfactant, wherein the surfactant includes at least one alkyl polyglucoside; a water-soluble cellulose ether base material substituted with a hydrophobic group having a carbon chain with 8 to 15 carbon atoms; wherein the water-soluble cellulose ether base material has a weight average molecular weight, Mw, of >800,000 Daltons; and wherein the personal care composition contains <0.01 wt % alkyl sulfate and <0.01 wt % alkyl ether sulfate.

Abstract: The present disclosure relates to a sprayable gel composition, comprising (a) from about 0.08% to about 1.8% by weight of a polysaccharide, (b) from about 0.002% to about 0.08% by weight of a divalent alkaline earth cation, (c) from about 0.1% to about 30% by weight of a humectant, (d) from 0% to about 30% by weight of an emollient, and (e) from about 40% to about 95% by weight of a cosmetically acceptable carrier, wherein the weight percentages are based on the total weight of all components of the sprayable gel composition, and to a method of treating hair in need of a conditioning treatment.

Abstract: A non-aqueous composition and method for reducing the drying time of wet hair includes applying added water to human hair to obtain wet hair and applying a nonaqueous serum comprising a combination of about 55 to about 65 percent by weight of at least one volatile silicone compound, about 30 to about 40 percent by weight of at least one high molecular weight silicone elastomer, a thermoprotective agent, an emollient, and a conditioning agent; applying the nonaqueous serum and heat to the wet hair in order to remove from about 80% to about 100% of the added water. In one embodiment, the application of the serum is capable of reducing a drying time of the wet hair by at least 25 percent.

Abstract: There is provided herein a method of treating thermally and/or chemically damaged including the following steps: contacting thermally and/or chemically damaged hair with a hair treating composition comprising a aminosilicone of the general formula (I): MDxD?yM??(I) wherein: M=R1R22SiO1/2 D=R22SiO2/2, and D?=R2R3SiO2/2, and where R1 is an alkyl group having 12 to 50 carbon atoms, R2 is a substituted or un-substituted hydrocarbon group having 1 to about 6 carbon atoms, R3 is 3-aminopropyl group and/or a N-(2-aminoethyl)-3-aminopropyl group, x has a value of 1 to about 2,000, and y has a value of 1 to about 50.

Abstract: Methods for treating a renal associated disease condition in a subject are provided. The subject methods are characterized by modulating at least one portion of the subject's autonomic nervous system in a manner effective to treat a renal condition in the subject. Specifically, the methods may include modulating, e.g., increasing, a parasympathetic/sympathetic activity ratio in the subject. Also provided are compositions, kits and systems for practicing the subject methods.

Abstract: The present invention relates to a topical ophthalmic formulation comprising at least one antagonist of the endothelin receptor, preferably selected from sitaxentan, ambrisentan, atrasentran, bosentan, macitentan and tezosentan, or a mixture thereof, more preferably bosentan. It also relates to the use of a topical ophthalmic formulation comprising at least one antagonist of the endothelin receptor, preferably selected from sitaxentan, ambrisentan, atrasentran, bosentan, macitentan and tezosentan, or a mixture thereof, more preferably bosentan, as active ingredient for preventing and/or treating the retinal neurodegeneration induced by diabetes and/or aging.

Abstract: Certain embodiments involve administering a residence structure to a subject (e.g., a patient) in a constrained configuration, then unconstraining the structure such that it is retained at a location internally of the subject for a period of time. The structure includes a loadable component that can carry an active substance for release internally of the subject.

Abstract: Certain embodiments involve gastric residence structures which can be administered to a subject (e.g., a patient) in a configuration constrained by a retaining element, and configured to mediate a change in shape when unconstrained by the retaining element to assume a configuration in the stomach in which is retained and unable to pass through the gastric pyloric orifice of the subject under gastrointestinal physiological conditions. The residence structures can be loaded with an agent for release in the stomach.

Abstract: Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting ?2 adrenergic receptor agonists via a metered dose inhaler. In particular embodiments, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.

Abstract: Provided herein are topical formulations. The topical formulation may comprise: (i) pregabalin, (ii) water, (iii) DMSO, (iv) a keto acid, and (v) and/or a fatty alcohol. The topical formulation may also comprise (i) pregabalin, (ii) DMSO, (iii) a keto acid and (iv) a fatty acid ester. It has been discovered that the combinations of DMSO with a keto acid such as levulinic acid and/or and a fatty acid ester such as lauryl lactate, or combinations of DMSO with a keto acid such as levulinic acid and/or with a fatty alcohol such as oleyl alcohol are excellent penetration enhancers and, as such, can be incorporated in a skin-applied formulation to facilitate administration of pregabalin.

Abstract: A semiconductor device includes a substrate, a peripheral structure, a lower insulating layer, and a stack. The substrate includes a peripheral circuit region and a cell array region. The peripheral structure is on the peripheral circuit region. The lower insulating layer covers the peripheral circuit region and the cell array region and has a protruding portion protruding from a flat portion. The stack is on the lower insulating layer and the cell array region, and includes upper conductive patterns and insulating patterns which are alternately and repeatedly stacked.

Abstract: A pharmaceutical composition comprising a lipid component, an amphiphilic emulsifier, a polar liquid carrier, and one or more electrolytes, where the amphiphilic emulsifier forms lipid carrying micelles having a lipophilic core comprising the lipid component in the polar liquid carrier, and/or liposomes organized as a lipid bilayer and/or other particle configurations. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating ischemic conditions with reduced reperfusion injury.

Abstract: The present invention relates to liposomal compositions, comprising liposomes containing tetraether lipids (TELs), and further comprising the lipopeptide Myr-HBVpreS/2-48 (Myrcludex B) as part of said liposomes, as well as uses thereof for the prevention or treatment of hepatic disorders or diseases, and/or for the oral hepatic delivery of therapeutic and/or diagnostic agents.

Abstract: A method of preparing liposomal statins includes preparing a lipid solution including phosphatidylcholine, cholesterol, vitamin-E and an organic solvent and removing the solvent, forming a lipid cake. The lipid cake may then be hydrated with a first aqueous media. The hydrated cake may be mixed in a mixer and subjected to one or more freeze/thaw cycles and then extruded to form liposomes. A cryo-protective agent may be added to the liposomes and the liposomes may be lyophilized to provide a powder. A statin is added to the organic lipid solution or to the first aqueous media used for hydrating the lipid cake.

Abstract: Disclosed are methods for hydration of ST-246 particles comprising exposing said particles to moisture by conveying volumes of air containing moisture.

Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclose.

Abstract: Exemplary embodiments of the disclosure may be drawn to ingestible delivery devices. An ingestible delivery device may include a first compartment and a second compartment. A lipase may be contained within the first compartment, and a fat may be contained within the second compartment. The first compartment may be sealed from the second compartment prior to exposure to a trigger, preventing the lipase and the fat from contacting each other, and at least one of the first compartment or the second compartment may at least partially rupture upon exposure to the trigger, allowing the lipase and the fat to contact each other.