Abstract: Detecting a respiratory tract infection (RTI) based on changes in coughing sounds, which can provide an early warning of infection with a disease like COVID-19, as well as indications of its progression and severity. In one embodiment, the system includes smartglasses, with sensors mounted thereto, which include an acoustic sensor mounted at a fixed position relative to a user's head, and a movement sensor. A computer receives current measurements of the user, taken with the sensors, while there were head movements that characterize coughing, and also earlier measurements of the user, taken with the sensors, while the user had a known extent of the RTI and while there were head movements that characterize coughing. The computer detects a change relative to the known extent of the RTI based on a difference between the current measurements and the earlier measurements.

Abstract: ECG signal processor includes: a signal processing circuit configured to amplify an ECG signal detected by an electrode attached to a living body and output the ECG signal amplified; and a common-mode signal generation circuit configured to generate a common-mode signal for increasing an amplitude of a peak of the ECG waveform indicated by the ECG signal using the ECG signal amplified by the signal processing circuit and apply the common-mode signal generated to the electrode.

Abstract: In order to provide a highly reliable heart rate, this heartbeat detection device includes: a first detection unit that detects heartbeats from a vibration wave of a body surface of a user detected by a sensor; a second detection unit that extracts a vibration wave of heartbeats which are amplitude-modulated with a resonant frequency of a human body from the vibration wave of the body surface of the user, delays the extracted vibration wave by a predetermined period, and detects heartbeats from differences between the vibration wave before delay and the vibration waves after delay; and an output control unit that selects either the heartbeats detected by the first detection unit or the heartbeats detected by the second detection unit and determines and outputs a heart rate on the basis of the selected heartbeats.

Abstract: A wrist-worn device and a blood pressure measuring method based on the same are disclosed. The wrist-worn device comprises a main body and a wrist band connected to the main body, and further comprises: a photoelectric tube located on a back surface of the main body and configured to collect pulse data of a wearer; electrodes configured to collect electrocardiograph data of the wearer, an insulator located between two of the electrodes, for preventing both from a direct electrical connection; a circuit board electrically connecting the photoelectric tube and the electrodes, the circuit board calculating a blood pressure value based on the collected pulse data and the electrocardiograph data.

Abstract: We disclose a system and method for estimating values of hemodynamic parameters of a subject, by calibrating arterial pressure during one time and tracking arterial pressure at another time.

Abstract: A blood pressure measurement apparatus, a portable pressure measurement apparatus, and a calibration method for the blood pressure measurement apparatus are provided. The blood pressure measurement apparatus includes a pulse wave measurer configured to measure pulse wave data of a subject while a user pressurizes and depressurizes the blood pressure measurement apparatus, using a portable pressure measurement apparatus, and a communicator configured to receive pressure data that is applied to the blood pressure measurement apparatus during the pressurizing and the depressurizing of the blood pressure measurement apparatus, from the portable pressure measurement apparatus, the pressure data being measured by the portable pressure measurement apparatus. The blood pressure measurement apparatus further includes a processor configured to update a blood pressure estimation formula, based on the received pressure data and the measured pulse wave data.

Abstract: The system determines a fetal blood oxygenation level by activating two or more light sources, having different wavelengths, which are positioned on the maternal abdomen of a pregnant mammal to direct light into a maternal abdomen toward a fetus. The system then receives a maternal signal from a first photodetector, which is positioned on the maternal abdomen to receive reflected light that traverses maternal tissue. The system also receives a mixed signal from a second photodetector, which is positioned on the maternal abdomen to receive reflected light that traverses both maternal and fetal tissue. The system performs a filtering operation that removes maternal signal components from the mixed signal to produce a fetal signal. The system determines the fetal blood oxygenation level by performing a pulse-oximetry computation on the fetal signal. The system dynamically adjusts operational parameters in the face of changing variables, such as fetus position and depth.

Abstract: A heartbeat index determination apparatus may include a pulse wave acquirer configured to acquire a plurality of pulse wave signals that are measured using light of different wavelengths; and a processor configured to measure wavelength-specific heartbeat index values from the plurality of pulse wave signals and determine that a wavelength-specific heartbeat index value that is obtained from the plurality of pulse wave signals a most number of times among the wavelength-specific heartbeat index values is a heartbeat index value of a user.

Abstract: A biocompatible microelectrode for in vivo and/or in vitro instant monitoring of the neurotransmitter release and reuptake for brain diseases and behavior disorders, which has a recording surface located on the end portion that contacts the neurotransmitter and a conductive circuit which is positioned on the holding portion which enables holding the biocompatible microelectrode during application, and which transfers the measurement data taken from the recording surface to sensors/measurement device. Selective and precise in vivo and in vitro measurement of the neurotransmitter is enabled by coating the isolated recording surface of the biocompatible microelectrode with a biocompatible surface coating.

Abstract: A method of mapping includes receiving inputs measured by a probe at respective locations inside a body cavity of a subject. At each of the respective locations, a respective contact quality between the probe and a tissue in the body cavity is measured. The inputs for which the respective contact quality is outside a defined range are rejected, and a map of the body cavity is created using the inputs that are not rejected.

Abstract: An ambulatory medical device including a plurality of sensing electrodes and one or more processors operably coupled to the plurality of sensing electrodes is provided. Each sensing electrodes is configured to be coupled eternally to a patient and to detect one or more ECG signals. The one or more processors are configured to receive at least one electrode-specific digital signal for each of the plurality of sensing electrodes, determine a noise component for each of the electrode-specific digital signals, analyze each of the noise components for each of the plurality of sensing electrodes, generate electrode matching information for each sensing electrode of the plurality of sensing electrodes based upon analysis of each of the noise components, determine one or more sensing electrode pairs based upon the electrode matching information, and monitor each of the one or more sensing electrode pairs for ECG activity of the patient.

Abstract: An apparatus comprising: at least one electrode, having a first potential, arranged to sense a biosignal; a conductive shield provided over the at least one electrode where the conductive shield is configured to be driven to a second potential wherein the second potential is equivalent to the first potential plus a multiple of an inverted common mode voltage; and wherein the conductive shield is coupled to a drain to enable triboelectric charges to be dissipated.

Abstract: Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals are acquired from a patient's body surface, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2D map, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2D map.

Abstract: A computer implemented method and system for confirming a device documented arrhythmia in cardiac activity are provided. The method is under control of one or more processors configured with executable instructions. The method obtains a cardiac activity (CA) data set that includes CA signals for a series of cardiac events and includes device documented (DD) markers within the series of cardiac events. The device documented markers are indicative of atrial fibrillation (AF) detected by the ICM utilizing an on-board R-R interval irregularity (ORI) process to analyze the CA signals. The method applies a feature enhancement function to the CA signals to form modified CA signals with enhanced sinus features and analyzes the enhanced sinus features in the modified CA signals. The method utilized a confirmatory feature detection process to identify false AF detection by the ORI process. The method records a result of the analysis identifying false AF detection by the ORI process.

Abstract: High-density mapping catheters with an array of mapping electrodes are disclosed. These catheters can be used for diagnosing and treating cardiac arrhythmias, for example. The catheters are adapted to contact tissue and comprise a flexible framework including the electrode array. The array of electrodes may be formed from a plurality of columns of longitudinally-aligned and rows of laterally-aligned electrodes.

Abstract: A catheter may be adapted to map a chamber of the heart. The catheter may include a magnetic and/or ultrasound sensor for navigation. The body of the catheter may be pliable and configured to form a predetermined shape upon exiting a catheter sheath. Upon exiting the catheter sheath, the catheter body may be configured to form one or more loops, and the loops may be non-overlapping loops. In some examples, the non-overlapping loops may be concentric loops. Alternatively, the catheter body may be configured to form one or more splines. The catheter body may include an embedded electrode assembly. The electrodes of the electrode assembly may be may be arranged in one or more rows and configured to detect a wave front. The electrode assembly may also be configured to generate and activation sequence and determine a direction of an activation source.

Abstract: An auscultatory sound signal from at least one auscultatory sound-or-vibration sensor is segmented into a plurality of associated heart cycle segments responsive to associated R-peak locations of an electrographic envelope signal representing an envelope response to an even power of an associated electrographic signal from an ECG sensor. A representation an envelope responsive to an even power of said auscultatory sound signal within said at least one heart cycle is locally modeled about at least a second peak to provide for locating the start of diastole of said at least one heart cycle.

Abstract: A biofeedback system capable of obtaining a real-time EEG response “in the field”, i.e. while a user is performing an activity in a real-world (non-clinical) setting, and capable of transforming the EEG response into a meaningful indicator of current mental state, and presenting that indicator to the user, e.g. in a form able to improve their performance of the activity. The system comprises a wearable sensor incorporated into headgear worn by the user during participation in an activity. A central processing unit is arranged to receive an EEG signal transmitted from the wearable sensor, and filter and analyse the EEG signal to generate output data that is indicative of mental state information for the user.

Abstract: Systems and methods are disclosed to detect and/or classify electrophysiological signals as motor events.

Abstract: A blood glucose tracking system and method measures emitted microwave energy transmitted to and accepted by blood vessels in a desired target area of a patient in order to determine, in real time and in vivo, appropriate blood glucose levels. A measurement unit comprises a transmitter operatively connected to an antenna to deliver energy towards appropriate subcutaneous blood vessels. The measurement unit determines an accepted energy power value in the blood vessels associated with the desired target area. This measurement energy power value is compared with a calibration value, and the difference is used to determine a resultant blood glucose value. The determined blood glucose value may further be acclimatized using additional sensed values compensating for biological and ambient factors relevant to the patient. The final determined blood glucose value can be displayed for reading and/or transmitted and stored for recording for further reference.

Abstract: A magnetic particle imaging device is provided. The device includes a magnetic field source configured to produce a magnetic field having a non-saturating magnetic field region, an excitation signal source configured to produce an excitation signal in the non-saturating magnetic field region that produces a detectable signal from magnetic particles in the non-saturating magnetic field region, and a signal processor configured to convert a detected signal into an image of the magnetic particles. Aspects of the present disclosure also include methods of imaging magnetic particles in a sample, and methods of producing an image of magnetic particles in a subject. The subject devices and methods find use in a variety of applications, such as medical imaging applications.

Abstract: The present disclosure directs to a system and method for automated positioning of a subject. The method may include obtaining a scout image of a subject when the subject is positioned at a first position in an apparatus. The method may also include determining location information of a reference structure of the subject based on the scout image. The method may also include determining an offset between the first position of the subject relative to a characteristic point of the apparatus according to the location information of the reference structure. The method may further include moving the subject to a second position based on the offset. The method may still further include performing, using the apparatus, a procedure relating to a target structure of the subject located at the second position.

Abstract: Tubes (e.g., catheters, endotracheal or chest tubes and bypass grafts) are provided, comprising a catheter and a plurality of sensors.

Abstract: Apparatus, including a magnetic tracking system, which generates a magnetic field near a living subject's body, and a probe, having a distal end that can contact registration points on a surface of the body. The probe has a contact sensor, located within the distal end, that outputs first signals indicative of a quality of the contact between the distal end with the registration points. Located within the distal end is a magnetic detector that outputs second signals that are indicative of respective positions of the registration points in a coordinate frame of the magnetic tracking system. A processor receives a tomographic image of the subject, and verifies, based on the quality of the contact indicated by the first signals, that the registration points are valid, and registers the tomographic image in the coordinate frame of the magnetic tracking system using the positions of the valid registration points.

Abstract: Ingestible devices capable of delivering a dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are disclosed. A removably attachable storage reservoir configured to be used with an ingestible device and capable of storing dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are also disclosed.

Abstract: The present disclosure describes a single-use microfluidic cartridge that is can be utilized with a portable and handheld breath collection and analysis device to detect a presence of a target chemical in human breath. The cartridge receives an air sample of human breath, processes it to extract the target chemical in solution, and reacts the solution with chemical reagent(s) to determine a concentration level of the target chemical present in the collected breath sample. Additionally, a portion of the collected sample can be contained in a separate reservoir of the cartridge of evidence preservation. The cartridge may further contain a cryptographic computing chip to store information regarding the sample processed within the cartridge.

Abstract: The present disclosure describes systems, methods, and apparatus for a portable and handheld mechanical breath collection device. The mechanical breath collection device collects air from a human subject, filters out saliva from the human subject, and collects aerosolized droplets from the received air via inertial impaction on an impactor surface. A target chemical is then extracted from the collected aerosolized droplets, and analyzed. In this way, a concentration of a target chemical present from the human subject can be determined by the portable and handheld device.

Abstract: This disclosure relates to systems, media, and methods for providing near-instantaneous feedback from real-time motion sensor data. In an embodiment, the system may perform operations including loading at least one target motion trigger. Disclosed embodiments may receive real-time sensor data from the first motion sensor detachably fixed to a user. Additionally, disclosed embodiments may include calculating a motion profile based on the real-time sensor data, the motion profile describing a multi-dimensional representation of acceleration of a motion performed by the user. Disclosed embodiments may also include comparing the at least one target motion trigger to the calculated motion profile to determine if the motion performed by the user corresponds to the target motion. Further, disclose embodiments may include transmitting, based on the comparison, an instruction to provide an alert to a user.

Abstract: The present invention relates to a device and a method for detecting whether a bedridden person is getting out of bed or has fallen out of their bed. The device performs an analysis over time of the distances between the sensors of a detector and the objects that are present in the detection field of the detector. The detection is based on variations in said distances and of the locations thereof within the monitored space.

Abstract: The abnormal data processing system is provided with: a storage unit for holding a multiple-subject DB in which data on multiple subjects are accumulated and individual-subject DB in which data on individual subjects are accumulated; an individual-subject DB divergence-degree calculation unit for calculating an individual-subject DB divergence degree which is the degree of divergence of the new data from the individual-subject DB; a multiple-subject DB divergence degree calculation unit for calculating a multiple-subject DB divergence degree which is the degree of divergence of the new data from the multiple-subject DB; and a composite divergence degree calculation unit for determining a composite divergence by compositing the individual-subject DB divergence degree and the multiple-subject DB divergence degree using the number of data instances in the individual-subject DB. The abnormal data processing system determines whether or not the new data is abnormal on the basis of the composite divergence degree.

Abstract: A method and apparatus for monitoring a human or animal subject in a room using video imaging of the subject and analysis of the video image to detect and quantify movement of the subject and to derive an estimate of vital signs such as heart rate or breathing rate. The method includes techniques for de-correlating global intensity variations such as sunlight changes, compensating for noise, eliminating areas not of interest in the image, and quickly and automatically finding regions of interest for detecting subject movement and estimating vital signs. A logic machine is used for interpreting detected movement of the subject, and an artificial neural network is used to calculate a confidence measure for the vital signs estimates from signal quality indices. The confidence measure may be used with a normal density filter to output estimates of the vital signs.

Abstract: A posture estimation device includes: a processor that: obtains detected information indicating a feature of a subject, wherein the feature is detected based on an image that is captured by an imager from a position where the subject is viewed from above, calculates a feature amount based on the obtained detected information, updates, based on a geometric relationship between the imager and the subject, a model parameter for estimating a posture of the subject by machine learning using the calculated feature amount in a time series, and estimates the posture of the subject using the updated model parameter.

Abstract: Ciliary motion in the upper airway is the primary mechanism by which the body transports foreign particulate out of the respiratory system. The ciliary beating frequency (CBF) is often disrupted with the onset of disease. Current imaging of ciliary motion relies on microscopy and high speed cameras, which cannot be easily adapted to in-vivo imaging. M-mode optical coherence tomography (OCT) imaging is capable of visualization of ciliary activity, but the field of view is limited. The present invention features the development of a spectrally encoded interferometric microscopy (SEIM) system using a phase-resolved Doppler (PRD) algorithm to measure and map the ciliary beating frequency within an on face region. This novel high speed, high resolution system allows for visualization of both temporal and spatial ciliary motion patterns.

Abstract: A non-invasive optical internal substance detector includes: a diode array including a plurality of light emitting diodes (LEDs) for emitting light toward a target where an internal substance is detected, and a plurality of photodiodes (PDs) for receiving light which is reflected from the target after being emitted from the plurality of light emitting diodes; and a controller for controlling the plurality of light emitting diodes to be turned on or off and for processing a signal obtained from the photodiodes. The plurality of light emitting diodes and the plurality of photodiodes each have a size of several micrometers to several tens of micrometers and are arranged at intervals of several micrometers to several tens of micrometers from each other.

Abstract: A contact assembly for electrically interconnecting at least two modules is disclosed. The contact assembly has a first module having a first contact pad and a second module having a second contact pad. The first and second contact pads are arranged nonparallel to one another. One of the first and second contact pads exerts pressure on an electrically conductive elastomer to thereby deform it, and the deformation results in the other one of the first and second contact pads being contacted by the electrically conductive elastomer. An electrochemical sensor may be part of the first module and an electronics assembly may be part of the second module. An insertion needle may also be provided to insert the sensor transcutaneously. Associated methods are disclosed.

Abstract: An electrochemical sensor is disclosed. The sensor has a substrate having a proximal part and an elongated distal part. Electrodes are formed on the distal part. The working electrode forms a conductive trace and multiple electrode pads are arranged along and connected by conductive trace. The electrode pads include a corrosive conductive layer covered by a non-corrosive conductive layer. The corrosive conductive layer is a metal less noble or as noble as Ag, and the non-corrosive conductive is a metal more noble than Ag. An insulating layer on the substrate has openings in the areas of the electrode pads. A protective measure for the corrosive conductive layer can be provided, such as having the insulating layer at least partially overlap the electrode pad edges, or providing at least one of the electrode pads with an elongated shape along the smaller dimension of the distal part.

Abstract: Provided is a formula and method for monitoring individual metabolic response that involve calculation of the lag/latency time (LT) for the peak levels of measured a variety of glucose values by HATR-FTIR (horizontally attenuated total reflection Fourier transform infrared) spectroscopy and the LT for the peak level of capillary blood glucose (CBG), with subsequent calculation of the LT changes between them. Obtained meaningful time-dependent and dose-dependent glucose values and their LT changes characterize glycemic variability (GV) in a qualified subject, that can be used to predict the patient's risk of hyperglycemia, to stage Type II diabetes and, in general, to be considered as a new metrics of assessing the quality of metabolic control.

Abstract: A continuous glucose monitoring system may utilize electrode current (Isig) signals, Electrochemical Impedance Spectroscopy (EIS), and Vcntr values to optimize sensor glucose (SG) calculation in such a way as to enable reduction of the need for blood glucose (BG) calibration requests from users.

Abstract: Apparatus and methods are operative to probe the condition of a sensor either initially, at any point thereafter or continuously during a continuous sensor operation for measuring an analyte in a bodily fluid (such as performed by, e.g., a continuous glucose monitoring (CGM) sensor). Results of the probe may include calibration indices determined from electrical signals obtained during the probe. The calibration indices may indicate whether in-situ adjustment of the sensor's calibration should be performed either initially and/or at random check points. Probing potential modulation parameters also may be used during analyte calculations to reduce the effects of lot-to-lot sensitivity variations, sensitivity drift during monitoring, temperature, interferents, and/or the like. Other aspects are disclosed.

Abstract: Apparatus and methods are operative to probe the condition of a sensor either initially, at any point thereafter or continuously during a continuous sensor operation for measuring an analyte in a bodily fluid (such as performed by, e.g., a continuous glucose monitoring (CGM) sensor). Results of the probe may include calibration indices determined from electrical signals obtained during the probe. The calibration indices may indicate whether in-situ adjustment of the sensor's calibration should be performed either initially and/or at random check points. Probing potential modulation parameters also may be used during analyte calculations to reduce the effects of lot-to-lot sensitivity variations, sensitivity drift during monitoring, temperature, interferents, and/or the like. Other aspects are disclosed.

Abstract: Various systems and methods are disclosed. One or more of the methods disclosed uses machine learning algorithms to predict biophysical responses from biophysical data, such as heart rate monitor data, food logs, or glucose measurements. Biophysical responses may include behavioral responses. Additional systems and methods extract nutritional information from food items by parsing strings containing names of food items.

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

Abstract: A photometry device can include a first to emit light to a target in response to a first current through the first LED, a second LED to emit light to the target in response to a second current through the second LED, and an inductor, coupled to the first and second LEDs, to store energy associated with at least one of the first and second currents.

Abstract: A method providing a signal quality degree associated with an analyte value measured in a continuous monitoring system is disclosed. The method includes: receiving a measured analyte value from a biosensor; determining at least two impact parameters, wherein each of the impact parameters is influenced by an operational status of the continuous monitoring system and wherein each of the impact parameters is capable of exerting an influence on the signal quality of the biosensor and wherein the influence of each of the impact parameters on the signal quality of the biosensor is expressed by a weight assigned to each of the impact parameters; and determining the signal quality degree associated with the measured analyte value as a function of the weights and the corresponding impact parameters; and providing the signal quality degree associated with the analyte value. A method of calibration using the signal quality degree is also disclosed.

Abstract: A transcutaneous sensor device configured for continuously measuring analyte concentrations in a host is provided. In some embodiments, the transcutaneous sensor device 100 comprises an in vivo portion 160 configured for insertion under the skin 180 of the host and an ex vivo portion 170 configured to remain above the surface of the skin 180 of the host after sensor insertion of the in vivo portion. The in vivo portion may comprise a tissue piercing element 110 configured for piercing the skin 180 of the host and a sensor body 120 comprising a material or support member 130 that provides sufficient column strength to allow the sensor body to be pushable in a host tissue without substantial buckling. The ex vivo portion 170 may be configured to comprise (or operably connect to) a sensor electronics unit and may comprise a mounting unit 150. Also described here are various configurations of the sensor body and the tissue piercing element that may be used to protect the membrane of the sensor body.

Abstract: The present invention extends to methods, systems, and computer program products for forecasting mood changes from digital biomarkers and more generally for forecasting changes in a neuropsychological clinical assessment. User interaction data indicative of a user's interaction with a mobile device is passively captured over a period of time and can include keyboard timings. A function mapping is executed to compute a digital biomarker for a brain health metric from the captured user interaction data. A prior digital biomarker for the brain health metric (computed from previously captured user interaction data by executing the function mapping) is accessed. A difference is detected between the digital biomarker and the prior digital biomarker. A change in a score of the neuropsychological test score is forecast to occur within a specified time range in the future based on the detected differences. The forecast change is output.

Abstract: The safety process covering a vehicle having driving apparatus and a station designed for a person and a person fitted with a medical device, in which: the medical device is designed to work in response to the physiological data of the person with a device and trigger an alarm signal in case of malfunctioning of the medical device per se and alarm signal for any actual or inferred problem regarding the medical condition of the person fitted with a device.

Abstract: Disclosed is a system for objective self-assessment of physical capabilities and condition changes of individuals with conditions like multiple sclerosis, the system has a mobile device with an appropriate software for carrying out a set of tests for assessment of motor capabilities such as body balance, muscle strength, and muscle spasticity, and receiving assessment feedback. The system has inertial motion sensors for performing motion sensing, wherein said inertial motion sensors are integrated with said mobile device, e.g., a smartphone, a smart watch, or a personal computer, or in a separate wearable sensor device, connected with said mobile device over wired or wireless data connection. Also disclosed is a method for such self-assessment with such system.

Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.

Abstract: Breast monitoring systems and methods are described including a flexible substrate fabricated to substantially conform to one or more breasts of a subject; dynamically bendable optical fibers associated with the flexible substrate; a light source operably coupled to the optical fibers; a photodetector positioned to detect light reception from the optical fibers; a reporting device; and a microcontroller including a microprocessor and circuitry, wherein the circuitry includes input circuitry configured to receive a first set of signals and at least one second set of signals from the photodetector; calculation circuitry configured to calculate a curvature delta value based on a comparison of the received first and at least one second set of signals, and calculate a breast volume delta value from the calculated curvature delta value; and reporting circuitry configured to transmit a signal to the reporting device based on the calculated breast volume delta value.