Abstract: A current generation architecture for an implantable stimulator device such as an Implantable Pulse Generator (IPG) is disclosed. Current source and sink circuitry are both divided into coarse and fine portions, which respectively can provide coarse and fine current resolutions to a specified electrode on the IPG. The coarse portion is distributed across all of the electrodes and so can source or sink current to any of the electrodes. The coarse portion is divided into a plurality of stages, each of which is capable via an associated switch bank of sourcing or sinking a coarse amount of current to or from any one of the electrodes on the device. The fine portion of the current generation circuit preferably includes source and sink circuitry dedicated to each of the electrode on the device, which can comprise digital-to-analog current converters (DACs).

Abstract: Peripheral nerve field stimulation (PNFS) may be controlled based on detected physiological effects of the PNFS, which may be an efferent response to the PNFS. In some examples, a closed-loop therapy system may include a sensing module that senses a physiological parameter of the patient, which may be indicative of the patient's response to the PNFS. Based on a signal generated by the sensing module, the PNFS may be activated, deactivated or modified. Example physiological parameters of the patient include heart rate, respiratory rate, electrodermal activity, muscle activity, blood flow rate, sweat gland activity, pilomotor reflex, or thermal activity of the patient's body. In some examples, a patient pain state may be detected based on a signal generated by the sensing module, and therapy may be controlled based on the detection of the pain state.

Abstract: This disclosure relates to an active medical device which includes a generator for producing multiphase nerve stimulation pulse trains, each pulse train including at least one stimulation pulse preceded by a precharge pulse and ending with a passive discharge pulse. The active medical device also includes a sensor configured to output a control signal representative of a physiological and/or physical parameter capable of being influenced by the output of nerve stimulation pulse trains. The active medical device also includes an automatic charge compensation control circuit configured to receive at the input the control signal output by the sensor, determine an amplitude and/or a precharge pulse time as a function of at least one predetermined criterion, and output to the generator a precharge pulse control signal to be produced at the output.

Abstract: Systems and methods for stimulation of neurological tissue apply a stimulation waveform that is derived by a developed genetic algorithm (GA), which may be coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The waveform is optimized for energy efficiency.

Abstract: A pacemaker having a motion sensor delivers atrial-synchronized ventricular pacing by detecting events from a signal produced by the motion sensor and delivering ventricular pacing pulses at a rate that tracks the rate of the detected events. The pacemaker is configured to confirm atrial tracking of the ventricular pacing pulses by determining if detected events from the motion sensor signal are atrial events. The pacemaker is configured to adjust a control parameter used for detecting events from the motion sensor signal if atrial tracking is not confirmed.

Abstract: An external control device for use with a neurostimulation system having a plurality of electrodes capable of conveying an electrical stimulation field into tissue in which the electrodes are implanted is provided. The external control device comprises a user interface having one or more control elements, a processor configured for generating stimulation parameters designed to modify the electrical stimulation field relative to one or more neurostimulation lead carrying the electrodes. The external control device further comprises output circuitry configured for transmitting the stimulation parameters to the neurostimulation system.

Abstract: A method is described for percutaneously delivering an implant through a region of a body of a subject, the region including a fascia and non-fascia tissue. A hollow needle of a delivery tool is advanced distally through the fascia, while the delivery tool is in a first state in which the implant is entirely housed within the needle. The delivery tool is switched to a second state in which a proximal portion of the implant is housed within the needle and a distal portion of the implant is exposed from a distal end of the needle. While the delivery tool is in the second state the hollow needle is advanced distally through non-fascia tissue. Other embodiments are also described.

Abstract: A leadless cardiac pacemaker is provided which can include any number of features. In one embodiment, the pacemaker can include a tip electrode, pacing electronics disposed on a p-type substrate in an electronics housing, the pacing electronics being electrically connected to the tip electrode, an energy source disposed in a cell housing, the energy source comprising a negative terminal electrically connected to the cell housing and a positive terminal electrically connected to the pacing electronics, wherein the pacing electronics are configured to drive the tip electrode negative with respect to the cell housing during a stimulation pulse. The pacemaker advantageously allows p-type pacing electronics to drive a tip electrode negative with respect to the can electrode when the can electrode is directly connected to a negative terminal of the cell. Methods of use are also provided.

Abstract: Certain medical devices, such as auditory prostheses, have an implantable portion and an external portion. The implantable portion and external portion each include a transmission/receiver coil that communicates signals between the two portions. The implanted coil is implanted about the ear canal while the external coil is disposed about the pinna or in the ear canal itself. The proximity of the two coils allows for signal transmission between the implantable and external portions.

Abstract: Systems and methods for detecting cardiac arrhythmias such as an atrial fibrillation (AF) are described herein. The AF detection system includes a sensor circuit to sense a physiological signal, a heartbeat processor to recognize a plurality of beat patterns using cycle length of two more consecutive cardiac cycles. The beat patterns can be indicative of temporal relationship between the consecutive cardiac cycles. The heartbeat processor may generate a repetitiveness indictor based on a statistical measurement of various beat patterns. The AF detection system includes an arrhythmia detector to detect an episode of AF based on the repetitiveness indictor, and to discriminate the AF from other arrhythmias of atrio-ventricular conduction abnormalities.

Abstract: A wearable cardiac defibrillator (“WCD”) system may include a support structure that a patient can wear, an energy storage module that can store an electrical charge, and a discharge circuit that can discharge the electrical charge through the patient so as to shock him or her, while the patient is wearing the support structure. Embodiments may actively take into account bystanders, both to protect them from an inadvertent shock, and also to enlist their help. In some embodiments, the WCD system includes a speaker system and a memory. Prompts have been saved in advance in the patient's own voice, and stored in the memory. In case of an emergency, the prompts may be played by the speaker system in the patient's own voice, and heard by a bystander.

Abstract: A coil has 1st to Nth turns. The 1st to Nth turns respectively provided with actuation parts for current in one direction to flow, and connection parts for current in the opposite direction to the one direction to flow. The plurality of actuation parts are arranged substantially parallel to each other, and are arranged along a surface of an object or a surface that approximates to the surface of the object. A plurality of connection parts are arranged within a space in which the connection parts do not face the surface of the object over the actuation parts of the 1st to Nth turns, and the connection parts are positioned at the sides with respect to the extension direction of the actuation parts.

Abstract: Photobiomodulation therapy (PBMT) can be applied to a tender area on a subject's body to treat fibromyalgia. A light source device can be contacted to a subject's skin proximal to a tender area on the subject's body. A light signal (with wavelengths from the red to infrared part of the spectrum) can be applied in at least one of a pulsed operating mode, a continuous operating mode, and a super-pulsed operating mode through the light source device to the tender area. The light signal is applied for a time sufficient to stimulate a phototherapeutic response in the tender area to treat fibromyalgia.

Abstract: A brassiere is configured to administer electromagnetic therapy to treat a cancerous tumor within a breast. The brassiere includes at least one cup, the cup within its walls at least two magnetic coils (also referred to herein as solenoid coils). Each solenoid coil is energized, when in therapeutic operation, with a distinct time-domain signal. The time domain signal consists of a series of summed sinusoidal waves from a power supply. The coils are oriented within the wall of the cup such that for any two coils a first magnetic coil and a second magnetic coil are oriented relative to each other so as to be nonparallel. The purpose of having two distinct coils is to focus resultant magnetic fields such that at a tumor site within a volume of breast tissue the cup encloses to form a local maximum formed by superposition within the cancerous tumor.

Abstract: Neural stimulator systems with an external magnetic coil to produce changing magnetic fields is applied outside the body, in conjunction with one or more tiny injectable objects that concentrates the induced electric field to a highly-targeted location. These systems include a driver circuit for the magnetic coil that allows for high voltage and fast pulses in the coil, while requiring low-voltage power supply that may be powered by a wearable or portable external device, along with the coil and driver circuit.

Abstract: A personal therapy compartment includes a base of size to receive a human patient. The compartment includes a bed in the base said bed being made of a light transmissive material. An array of lights mounted is below the bed to transmit light onto a body supported on the bed. A control panel controls at least the wavelength, intensity and pulsation of the light.

Abstract: Disorders of the eye can be treated by photobiomodulation therapy according to a device designed to direct light into a patient's eye, no matter the configuration of the eye. The device, including a printed circuit board that includes an array of light delivery devices and a heat sink lens, can be placed proximal to the patient's eye. The light delivery devices can be powered to generate light. The light can be directed into the patient's eye regardless of a position of the patient's eye.

Abstract: A control circuit accesses information regarding a plurality of pre-existing vetted radiation treatment plans for a variety of patients and uses that information to train at least one model (such as a dose volume histogram estimation model). The control circuit then uses that model to develop estimates for a radiation treatment plan for a particular patient. The control circuit can then use those estimates to develop a candidate radiation treatment plan.

Abstract: The present invention relates to the field of radiation therapy. In particular, the present invention relates to methods for treatment planning for a radiation therapy system. The method includes setting a number of objectives reflecting clinical criteria are set for the regions of interest and generating radiation dose profiles to be delivered to these regions of interest. A convex optimization function for optimizing the delivered radiation based on the objectives is provided and dose profiles for specific treatment configurations including beam shape settings for the radiation dose profiles are calculated using the convex optimization function. Treatment plans including determining the radiation dose profiles to be delivered during treatment based on the treatment configurations are created and an optimal treatment plan that satisfies the clinical criteria is selected.

Abstract: The invention relates to system and a method for adapting a radiotherapy treatment plan for treating a target structure within a target region of a patient body, where a planning unit (7) adapts the treatment plan on the basis of a set of influence parameters quantifying an influence of the radiation on the target region per unity intensity emission in accordance with an anatomical configuration of the target region. In a storage (8), a plurality of sets of influence parameters is stored, each set being associated with an image of the body region representing a particular anatomical configuration of the target region and the planning unit (7) is configured to select the set of influence parameters from the stored sets on the basis of a comparison between a captured image of the body region and at least one of the images associated with the sets of influence parameters.

Abstract: In order to provide a neutron therapy apparatus which give multi angles neutron beam irradiation, the neutron therapy apparatus includes: a beam shaping assembly including a moderator and a reflector surrounding the moderator, wherein the moderator moderates neutrons to a predetermined energy spectrum and the reflector guides deflected neutrons back to enhance the neutron intensity in the predetermined energy spectrum; a neutron generator embedded inside the beam shaping assembly, wherein the neutron generator generates neutrons after irradiated by an ion beam; and an irradiation room for receiving a irradiated object, a shielding assembly connected to the beam shaping assembly, wherein the shielding assembly moves together with the beam shaping assembly and shields the radioactive rays leaked from the beam shaping assembly all the time.

Abstract: An apparatus for communicating with a radiation therapy device comprises a first plurality of omnidirectional radio antennas 212, 214 mounted upon a rotor 202, and a second plurality of omnidirectional radio antennas 216, 218 positioned at respective fixed locations off the rotor. The first plurality of antennas 212, 214 may be substantially equally spaced around the axis of rotation of the rotor 202. The first plurality of antennas 212, 214 and the second plurality of antennas 216, 218 are positioned so as to allow line-of-sight radio communication between at least one of the first plurality of antennas and at least one of the second plurality of antennas at all angles of rotation of the rotor 202.

Abstract: Described herein are implantable devices configured to emit an electrical pulse. An exemplary implantable device includes an ultrasonic transducer configured to receive ultrasonic waves that power the implantable device and encode a trigger signal; a first electrode and a second electrode configured to be in electrical communication with a tissue and emit an electrical pulse to the tissue in response to the trigger signal; and an integrated circuit comprising an energy storage circuit. Also described are systems that include one or more implantable device and an interrogator configured to operate the one or more implantable devices. Further described is a closed loop system that includes a first device configured to detect a signal, an interrogator configured to emit a trigger signal in response to the detected signal, and an implantable device configured to emit an electrical pulse in response to receiving the trigger signal.

Abstract: The invention relates to photocurable compositions comprising at least one inorganic gelling agent.

Abstract: A formulation for a nail polish composition which is curable with UV light is provided. The composition can be applied in a single coating and does not include solvents such as tolualene, dibutyl phthalate, or formaldehyde. The coating once cured provides multi-coating results using only a single coating and can be covered with an optional gloss or other decorative top coating.

Abstract: A mask is provided that can inactivate viruses adhering thereto even in the presence of lipids and proteins regardless of whether or not the viruses have an envelope. The mask can inactivate viruses adhering thereto and includes a mask body provided with a member used when the mask is worn and virus inactivating fine particles having a virus inactivating ability and held by the mask body. The virus inactivating fine particles are particles of at least one selected from the group consisting of platinum(II) iodide, palladium(II) iodide, silver(I) iodide, copper(I) iodide, and copper(I) thiocyanate.

Abstract: A semi-disposable face mask has a shaped molded base composed of silicone and/or TPE and molded forming a face seal, a filter media and a support structure that houses the shaped molded base and filter media in fluid communication allowing airflow from an environment through the filter media to the face seal.

Abstract: A roof anchor, roof anchor safety system, and method of using the same is provided herein. The roof anchor is generally for or use with a roof frame having an overhang, and has a base plate having a bottom surface configured to engage a field of the roof in a substantially planer direction, a hook portion contiguous with the base plate and having an inner surface, the inner surface of the hook portion adapted to sit proximate to or engage with the overhang of the roof, a wing contagious with the hook portion, the wing being configured to abut a portion of the overhang, wherein the base plate comprises a partially inverted portion having an aperture, the aperture adapted for coupling to a lifeline.

Abstract: A retractable fall arrest block comprising a spring side housing member and a drum side housing member. A center support wall, defining a bearing housing, is secured between the housing members. A bearing assembly is mounted in the bearing housing to support a spindle. A spring side housing member is mounted to a spring side of the center support wall and a spring side cover is mounted to the spring side housing member opposite the center support wall to define a spring housing. A drum side housing member is mounted to a drum side of the center support wall, and a drum side cover is mounted to the drum side housing member to define a drum housing. The spindle extends into both housings. A spring is mounted in the spring housing. A drum is positionally fixed to the spindle in the drum housing. A clutch assembly is mounted to the spindle to stop the drum from unwinding.

Abstract: A veneer panel may comprise an outer surface, and a heat resistant system coupled to the outer surface comprising at least one of a thermal barrier layer or an intumescent layer.

Abstract: A method of responding to a condition in an exhaust ventilation system that has an exhaust hood includes receiving, at a control module, an exhaust air temperature signal representing a temperature of the exhaust air in a vicinity of the exhaust hood, the exhaust air temperature signal being generated by a temperature sensor. The method also includes receiving a radiant temperature signal representing a temperature of a surface of a cooking appliance that generates the exhaust air, the radiant temperature signal being generated by a radiant temperature sensor. Further, the method includes receiving a pressure signal representing the pressure in the hood and determining a state of the cooking appliance based on the received exhaust air temperature signal, the received radiant temperature signal, and the received pressure signal. Finally, the method responds to the determined appliance state by outputting a control signal from the control module.

Abstract: A hub assembly includes a primary support defining a first primary support end and a second primary support end, the primary support defining a primary cut out portion; a secondary support defining a first secondary support end and a second secondary support end, the secondary support defining a secondary cut out portion, the second secondary support end defining a first opening and a second opening; a pin extending through the first primary support end and the first secondary support end, the pin hingedly coupling the first primary support end to the first secondary support end; and a locking mechanism extending through the second secondary support end, the locking mechanism including a first pin member engaging the first opening; a second pin member engaging the second opening; and a spring captured between the first pin member and the second pin member.

Abstract: A method of temporarily operating sprinklers and mobile sensors during buildings/facilities alterations, renovations, additions, repairs, rehabilitations, relocations and any other similar activities where personnel may trigger sprinkler systems through accidental actions (or inactions) during their chores. This minimizes the possibility of damages during the building's construction/renovation.

Abstract: A climate change reducing malodorous composition of matter that contains a liquid mercaptan mixed with a solvent, trans-1,3,3,3-tetrafluoroprop-1-ene, and a flame suppression component, trans-1-chloro-3,3,3-trifluoropropene, and with an inert gas such as nitrogen or carbon dioxide under pressure in a container for introduction into a pressurized breathing or pneumatic tool system, such as in mines, thereby forming a warning system to warn a person of danger when the malodorous composition of matter is released from the container.

Abstract: A composite floor mat having an upper layer, a middle layer, and a bottom layer. The upper layer comprises a durable wear surface, the middle layer comprises a plurality of pockets, each filled with an energy dissipative material. The bottom layer is bound to the upper layer and defines a perimeter of the mat and a network of ribs defining the pockets of the middle layer. A mat system comprises a plurality of mat components positioned adjacent one another, including edge mat components, corner mat components, and internal mat components, held together by retaining clips disposed in a channels of the mat components. A process for manufacture of a floor mat assembly, and product produced thereby, are also disclosed.

Abstract: An exercise board comprising a first top and second top rotatably engaged, wherein the first top has a first cavity and the second top has a second cavity, a board rotatably engaged along a first edge of the first board is rotatably engaged with a first edge of the first cavity, and a step foldable and comprised of a upper step and a lower step; a upper front panel extending between the upper step and the lower step and rotatably engaged to the upper step and the lower step; a lower front panel extend from the lower step and rotatably engaged with the lower step; a front and a rear side panels on each side of the steps being rotatable relative to one another; and a rear panel rotatably engaged with the upper step and both of the rear side panels rear panel.

Abstract: An exercise machine has a mobile base and an upright support extending upwards from the mobile base. An upper support assembly extends forward from an upper portion of the upright support and an exercise device is suspended from the upper support assembly at a location spaced forward from the upright support. The exercise machine may include a compact and safe counterbalancing gas spring mechanism that tends to move the exercise device away from the exerciser, and that requires a force to be applied to move an exercise device down towards the exerciser. The exercise machine may include an exercise device that is rotatable along a vertical axis, and may be coupled to an adjustable monitor for a wide range of uses. The exercise machine may be used by a exerciser lying supine, sitting in a chair or wheelchair, or standing in front of or adjacent the exercise machine.

Abstract: An exercise device comprises a base. A power mechanism and a vibration mechanism are each disposed in the base. The power mechanism powers the vibration mechanism. The vibration mechanism provides linear vibrations through the base of the device in a first axis parallel to a longitudinal axis of a user standing on the base. In some embodiments, the device is substantially free of vibration in a plane orthogonal to the first axis and is substantially free of rotational vibration in any direction at a time when the vibration mechanism provides the first plurality of linear vibrations. In some embodiments, the vibration mechanism operates between 10 and 60 Hz. In some embodiments an exercise kit is provided that includes the referenced exercise device, an exercise bar, and one or more elastic bands, each elastic band for removably coupling the base to the exercise bar.

Abstract: An exercise machine is provided for agonist-antagonist muscle training. A first variable resistance mechanism has a first line extending therefrom, a second variable resistance mechanism has a second line extending therefrom, and a user-engaged link is coupled to the first line and second line with the first line, second line, and link being aligned along a common axis. When the user applies a first tensile force to the first line via the link, the first line extends from the first variable resistance mechanism against its resistance force while the second line retracts towards the second variable resistance mechanism under its restoring force. Then, when the user applies a second tensile force to the second line via the link, the second line extends from the second variable resistance mechanism against its resistance force while the first line retracts towards the first variable resistance mechanism under its restoring force.

Abstract: A weight training machine generally includes a supportive frame, a first mechanism, and a second mechanism. The first mechanism includes a first weight stack, a first cable system, and a second cable system. The second mechanism includes a second weight stack, a third cable system, and a fourth cable system. In each of the first and second mechanisms, one end of a cable can be easily attached to a moving pulley block to have the moving pulley block converted to a fixed pulley block. As a result, the force applied to a handle for lifting the associated weight stack becomes double as compared to the cable being not attached to the moving pulley block.

Abstract: A collapsible weightlifting bar, comprising: two halves bisected from a weightlifting bar; a hollow, tubular splint; and, removably attachable hardware to secure the two halves to the splint. The weightlifting bar is configured to be adjustable in overall length and is configured to be collapsible for more efficient storage and transport.

Abstract: A bed with an exercise function includes: an upper exercise arm which is embedded in an insertion groove formed in a front surface or peripheral part of the head part, has a horizontal bar and leg parts extending downward from both ends of the horizontal bar, and is rotatable to protrude forward by a rotary support part provided at a lower end of the leg part; and a rotation stopping part which is coupled to the upper exercise arm and stops rotation of the upper exercise arm in a state in which the upper exercise arm protrudes forward at a predetermined angle.

Abstract: A method of differentially tuning a lower limb muscle in a human in need thereof is provided. The method includes placement of at least two calibrated, differential disturbances or protuberances under the human's feet thereby tuning a lower limb muscle.

Abstract: An exercise handle that includes a clamp configured to secure the exercise handle in place. The clamp includes a first portion that includes a first section and a second section. The clamp also includes a spring within the first portion. The spring biases the clamp in a closed position. The clamp further includes a second portion, where the second portion includes a first arm on the first section and a second arm on the second section. The exercise handle also includes a first block attached to the first arm of the second portion and a second block attached to the second arm of the second portion. The exercise further includes a handle. The handle includes a first segment, the first segment placed around at least some of the first portion and a second segment extending perpendicularly from the first segment and rotates relative to the first portion.

Abstract: An exercise machine which allows for a wide range of exercises while maintaining improved balance and control for the exerciser. The exercise machine generally includes a frame having a first track, a carriage movably connected to the first track, a first platform and a second platform connected to the frame, a first stationary handle extending upwardly from the upper surface of the first platform, and a second stationary handle extending upwardly from the upper surface of the first platform.

Abstract: Training at the proper level of effort is important for athletes whose objective is to achieve the best results in the least time. In running, for example, pace is often monitored. However, pace alone does not reveal specific issues with regard to running form, efficiency, or technique, much less inform how training should be modified to improve performance or fitness. A sensing system and wearable sensor platform described herein provide real-time feedback to a user/wearer of his power expenditure during an activity. In one example, the system includes an inertial measurement unit (IMU) for acquiring multi-axis motion data at a first sampling rate, and an orientation sensor to acquire orientation data at a second sampling rate that is varied based on the multi-axis motion data.

Abstract: Roughly described, a computer system uses a behavior-driven algorithm that is better able to find optimum solutions to a problem by balancing the use of fitness and novelty measures in evolutionary optimization. In competition among candidate individuals, a domination estimate between a pair of individuals is determined by both their fitness estimate difference and their behavior difference relative to one another. An increase in the fitness estimate difference of one individual of the pair over the other increases the domination estimate of the first individual. An increase in the behavior distance between the pair of individuals decreases the domination estimate of both of the individuals. Individuals with a higher domination estimate are more likely to survive competitions among the candidate individuals.

Abstract: The technology disclosed here involves analyzing an activity session. An example method involves receiving activity data indicative of an activity of a user, the activity data comprising a plurality of measurements associated with multiple parameters monitored during an activity session; retrieving a set of criteria corresponding to an activity type, wherein the set comprises a criterion related to a biomedical parameter and a criterion related to a resistance parameter; classifying, based on the set of criteria, the received activity data into a plurality of segments, wherein a first segment comprises a portion of the activity data corresponding to the activity type; accessing historical data associated with the user, the historical data comprising a second segment of historical data corresponding to the activity type; comparing the first segment comprising the portion of the received activity data and the second segment comprising historical data; and generating output based on the comparing.

Abstract: A swim fin includes a foot pocket with a front and rear sections and an upper portion. The upper portion has a dorsal region, and first and second debossed regions with the dorsal region disposed between the debossed regions. The first and second debossed regions are laterally positionable adjacent the metatarsophalangeal joints of the foot of the user. The debossed region includes grooves formed therein. The foot pocket includes a foot pocket cavity. The swim fin further includes a fin blade extending from the front section of the foot pocket. The fin blade has a distal edge, a blade body disposed between the distal edge and the front section, and first and second triple-bladed rails. The triple-bladed rails are disposed longitudinally along the foot pocket and the blade body with the foot pocket and the blade body disposed between the first and second triple-bladed rails.

Abstract: Golf balls having covers made of thermoplastic polyurethane compositions are provided. Multi-piece golf balls can be made. Polyurethane primer coatings and polyurethane top-coatings are applied to the thermoplastic polyurethane cover. Isocyanate-rich and polyol-rich polyurethane coatings can be applied. In one embodiment, multi-functional imine and amine compounds can be used to treat the golf ball. The resulting coating may contain polyurethanes, polyureas, and hybrids, copolymers, and blends thereof. The cover composition and surface coatings can further include catalysts, ultraviolt (UV)-light stabilizers, and other additives. Heat is used to cure the coatings. The coating methods have many benefits and the finished balls have good physical properties.