Abstract: A method for the prevention of brain damage and dysfunction after blunt or blast types of TBI by a single systemic dose application either intravenous (i.v.) or intraperitoneal (i.p.) of a pharmacological “opener” of KCNQ (“M-type”) potassium ion channels in brain.

Abstract: A method for the prevention of brain damage and dysfunction after blunt or blast types of TBI by a single systemic dose application either intravenous (i.v.) or intraperitoneal (i.p.) of a pharmacological “opener” of KCNQ (“M-type”) potassium ion channels in brain.

Abstract: The present invention involves systems and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.

Abstract: A detection device is disclosed and the detection device includes: a body, including a first groove and a first opening; the first opening is on a first surface of the body and in communication with the first groove; a collector, configured to be at least partially accommodated into the first groove in a rotatable manner and being capable of rotating to allow at least part of the collector to extend out of the first opening in a process of detection; a test paper supplier, disposed on the first surface and configured to provide a test paper on a side of the first opening away from the first groove in the process of detection so as to collect a detection sample; and a detector, disposed on the first surface and configured to detect the test paper that has collected the detection sample.

Abstract: A sleeve that may be worn on a limb of a user is disclosed. The sleeve may be used to assess shape, position, and movement of the limb, as well as biometric properties of the user. The sleeve may include a geometric pattern of conductive elastic material interspersed with non-conductive elastic material. A plurality of sensor units may be integrated in the sleeve with portions of the conductive elastic material coupled between sensor units. The sensor units may assess resistances of the portions of the conductive elastic material between the sensor units. A positioning component may be positioned at a joint of the limb when the sleeve is worn. The sleeve may include inertial measurement units integrated in the sleeve and positioned on upper and lower portions of the joint. A processor may receive and assess data from the sensor units and the first and second inertial measurement units.

Abstract: An thin walled elongated hollow lumen medical device structure comprised at least in part of a cylindrical flexible circuit. The cylindrical flexible circuit is configured in such a way to carry at least part of the device structural loads and therefore reduce the medical device total wall thickness. An exemplary embodiment of the invention structure comprises a hollow lumen medical catheter where a flexible circuit comprises the entire inner lumen and the outer lumen is comprised of a polymer extrusion.

Abstract: An apparatus includes a shaft and an end effector at a distal end of the shaft. The end effector is sized to fit in an anatomical passageway within a subject's cardiovascular system. The end effector includes at least one electrode pair that is configured to contact cardiovascular tissue and thereby pick up electrocardiogram signals. Each electrode pair includes first and second electrodes spaced apart along a longitudinal axis from each other by a gap area located between the electrodes, the gap area having a gap length with respect to the longitudinal axis such that a length of one of the electrodes along the longitudinal axis is equal to or greater than the gap length; and a ratio of an area defined by the gap area to one electrode area is equal to or less than one.

Abstract: A detection apparatus is for detecting interference on signal paths in a differential voltage measuring system with a signal measuring circuit for measuring bioelectric signals with a number of useful signal paths having at least one shield. In an embodiment, the detection apparatus includes at least one analysis unit, connected to the shield and embodied to detect interference in a useful signal path of the voltage measuring system via a signal measured at the shield in the case of interference.

Abstract: This disclosure provides a monitoring apparatus and a statistical display method for physiological parameter(s) thereof.

Abstract: Techniques are disclosed related to using anatomical mask data acquired via magnetic resonance imaging (MRI) scans to train a convolutional neural network (CNN). The training may include the verification of cardiac scar tissue locations data obtained from the anatomical mask data with a reliable system for doing so, such as ground truth data from enhanced cardiac MRI late gadolinium enhanced (LGE) scans. Once the CNN is adequately trained using the anatomical mask data, the CNN may be used to identify cardiac scar tissue from image data obtained from medical imaging modalities other than MRI.

Abstract: A body monitoring system is designed for patients of varying needs with patients at risk for seizures, epilepsy, stroke, heart attack, bedsores, dementia, mental disorders, Old aged people on elderly, children specifically hyperactive ones. This system provides the user the control by online observation and activities algebra sum table sand database. The system has two warning systems: in APP and cell phone in the emergency. A plurality of sensors measuring angle and movement and acceleration in the XYZ axes in combination with a plurality of GPS sensors and GPS boundary makers and a heart rate sensor is used. Show and control and monitoring positions of the body during resting and the time and place activities and body movement of patients the states and tensions have problems psychological. Online display current status of patient and saving the states and conditions of the patient.

Abstract: A system and method for treating cancer by integrating a hemodynamic parameter (Hdp) monitoring system and a radiofrequency generator synchronized by a processing system is disclosed. The system is capable of identifying health condition-specific Hdp variation values changes in a patient upon the exposure of low energy amplitude modulated electromagnetic fields frequencies. The exposure of the modulated frequencies influences cellular functions, such as microtubule conductivity, or malfunctions in a patient and can provide both a therapeutic and predictive and prognostic effect for the patient, providing for both treatment of a specific ailment or disease such as hepatocellular carcinoma as well as predictive results of how effective the treatment is likely to be. The construction of a library of frequencies can be used to more efficiently and effectively diagnose and treat a health condition in patients by auto-tuning a treatment regimen specifically to the patient.

Abstract: Embodiments of systems and methods for rules based assessment of endovascular coil stability are disclosed. These systems and methods may assess images from a patient taken at a first time, such as a time of initial coil placement or thereafter, and at one or more second times, using a set of rules. Based on this assessment, a predictive recurrence indicator predictive of recurrence of the coil in the patient may be determined and presented to a user of the system (such as a doctor or other clinician). This predictive recurrence indicator can then be utilized to determine if further procedures should be undertaken to diagnose or treat the patient.

Abstract: Provided are a biosignal visualizing system, which may easily learn a biosignal, may easily make a diagnosis, and may perform analysis in real time, and an effective pattern extracting method using the same, in order to determine a disease using a biosignal via deep learning.

Abstract: An information display method displays brain activity information calculated using a biological signal measured from a living body so as to be superimposed on a morphological image including a plurality of sectional images. The information display method includes: acquiring mask information representing an area belonging to a brain in the morphological image; and detecting one or more extremal value positions with spatial extremal values in the brain activity information based on the mask information. A sectional image corresponding to the one or more extremal value positions is acquired from the morphological image. A brain activity distribution corresponding to the sectional image is acquired. The brain activity distribution is displayed so as to be superimposed on the sectional image.

Abstract: Computed tomographic method and apparatus includes an electron or ion beam having a beam axis, a refractory metal disk; at least one slit in the refractory metal disk that receive the beam, wherein the slit is at an angle to the beam axis; a beam entrance opening in the slit that allows the beam to enter; an effective beam exit opening in the slit that allow the beam to exit, wherein the beam effective exit opening is smaller than the beam entrance opening; and a system for moving the beam across the refractory metal disk, wherein the beam enters the slit through the beam entrance opening and exits the slit through the effective beam exit opening; and a computed tomographic device for measuring the beam that enters and exits the slit for analyzing the beam.

Abstract: A patient support facility including at least one patient support plate and at least two supports for the patient support plate. Each of the supports are configured to be mobile has an autonomous drive module with a chassis permitting movements and rotations in all horizontal directions, a drive facility, and a control unit. The patient support facility includes a control facility that is configured to operate the drive modules in a coordinated and individual manner.

Abstract: A system and method of pose estimation to enable generation of high-quality 3D reconstruction volumes and fluoroscopic computed tomography images for the identification of small and ground glass lesions.

Abstract: A method and system is disclosed for acquiring image data of a subject. The image data can be collected with an imaging system with at least two different energy characteristics. The image data can be reconstructed using reconstruction techniques.

Abstract: A detection device for detecting radiation from a radiopharmaceutical administered to a subject includes a radiation sensor having a plurality of metal-oxide-semiconductor (MOS) components providing a pixel array, a semiconductor of the MOS components being configured for interaction charge carriers to be created in the depletion layer of the semiconductor in response to direct interaction with received charged particles emitted from the radiopharmaceutical. The detection device further comprises a light sealing covering arranged to prevent light from impinging on the pixel array. A laparoscopic probe, a handheld device and a specimen imaging chamber are also disclosed, and methods for operating the detection devices described herein.

Abstract: The present invention relates to a multimodal system for obtaining senological images by means of X-ray and MBI techniques.

Abstract: A Nuclear Medicine (N-M) imaging system including a gantry having a stationary stator and a rotor rotatably mounted on the stator and including detection units. The rotor is driven by a rotor driving assembly including a linear encoder. The detection units mounted on the rotor include scanning columns having one or more Multi-Pixel Photon Counter (MPC) mounted on one or more extendable arm. The gantry also includes flat cables connecting the controller with gantry components, e.g., the scanning column Multi-Pixel Photon Counters (MPC). The scanning columns are pivotably moveable by a scanning column driver system including a rotary encoder.

Abstract: The present invention relates to a device for aligning an X-ray grating to an X-ray radiation source, the device (10) comprising at least two flat X-ray grating segments (11-19); at least one alignment unit (31-39) for aligning one of the at least two flat X-ray grating segments; wherein the at least two flat X-ray grating segments (11-19) are arranged in juxtaposition and are forming an X-ray grating (20); wherein the at least two flat X-ray grating segments (11-19) each comprise a grating surface (41-49) for X-ray radiation, each grating surface (41-49) comprising a geometrical center; wherein normals (21-29) to each of the grating surfaces (41-49) define a common plane (73), wherein the normals (21-29) intersect the geometrical center of the grating surface (41-49); wherein at least a first of the at least two flat X-ray grating segments (11-19) is rotatable around an axis (131-139) that is perpendicular to the common plane (73); and wherein the first of the at least two flat X-ray grating segments (11-19)

Abstract: To improve breast mammography imagery via use of a digital “slot scanning” imaging system that accommodates the changing thickness of the breast from the chest wall to the nipple by scanning the breast from the chest outward to the nipple or vice versa instead of the side-to-side methodology and using Automatic Exposure Control or AEC parameters optimized for the changing thickness and composition of the breast at each scan location and an improved breast compression device, wherein uniform breast compression mechanism includes a first breast plate and a second breast plate, wherein at least one of said first breast plate and said second breast plates includes an angle adjustment or tilt to account for the high variability in breast sizes and configurations while maintaining optimal immobilization with excellent patient comfort.

Abstract: A method is for providing decision-supporting data. In an embodiment, the method includes receiving photon-counting computed tomography data relating to an examination region; determining a location of a thrombus in the examination region, based on the photon-counting computed tomography data received; generating the decision-supporting data, relating to at least one of the thrombus and a vascular wall in a region of the thrombus, based on the photon-counting computed tomography data received and the location of the thrombus determined; and providing the decision-supporting data generated.

Abstract: The disclosure provides a method and device for performing three-dimensional blood vessel reconstruction using projection images of a patient. The computer-implemented method includes receiving a first two-dimensional image of a blood vessel in a first projection direction and a three-dimensional model of the blood vessel. The method further includes determining, by a processor, a first optical path length at a selected position of the blood vessel based on the first two-dimensional image. The method also includes determining, by the processor, a second optical path length at the selected position of the blood vessel in the three-dimensional model. The method additional includes adjusting the three-dimensional model of the blood vessel, based on a comparison of the first optical path length and the second optical path length.

Abstract: An X-ray diagnostic apparatus according to an embodiment has a display configured to superimpose and display a plurality of X-ray irradiation ranges for generating a long range X-ray image on an image indicating a subject; and a display controller configured to change, based on an operation of a user, a position of an overlap region which is displayed on the display and at which the X-ray irradiation ranges which are adjacent to each other are overlapped.

Abstract: A digital X-ray detector is provided. The digital X-ray detector includes control circuitry. The control circuitry is configured to obtain an electromagnetic interference (EMI) frequency of an EMI signal, to receive a signal to start a scan, to ensure EMI noise is in a same phase during acquisition of offset images and read images to enable a subtraction of the EMI noise, and to start the scan.

Abstract: The apparatus is adapted to detect a tool based on a 3D image obtained by a 3D ultrasound imaging system. The apparatus comprises an image processing unit, which includes a tool detection module configured to perform a tool detection procedure. The tool detection procedure involves identifying a shadow of the tool in the 3D image and calculating the position of a “tool plane section” of the 3D image in which the entire length of the tool is represented.

Abstract: An overlay system can include a substantially planar overlay base including a top side. The base can define a handle receptacle, for instance at a first end of the base. The handle receptacle can include a handle capture section optionally having a tapered profile. A centrally located elongated guide can extend longitudinally along the top side of the base to guide translational movement of the ultrasound probe holder along a longitudinal axis of the base. A handle can be configured to be attached and detached, by a user, with the handle receptacle of the base. The handle can define a channel optionally having a wedge profile. The wedge profile of the handle can correspond to the tapered profile of the handle receptacle. Engagement of the channel to the capture section of the handle receptacle can attach the handle to the base.

Abstract: An intravascular imaging device (102) is provided. In some embodiments, the intravascular imaging device includes a flexible elongate member sized and shaped for insertion into a vessel of a patient, the flexible elongate member having a proximal portion and a distal portion; and an imaging assembly (110) disposed at the distal portion of the flexible elongate member, the imaging assembly including a flex circuit (214) positioned directly around the flexible elongate member. In some embodiments, a method of assembling an intravascular imaging device includes obtaining a flex circuit including a first layer having a plurality of transducers and a second layer having an acoustic backing material; and positioning the flex circuit directly around a distal portion of a flexible elongate member.

Abstract: A method of assembling an intravascular imaging device (102) is provided. In one embodiment, the method includes obtaining a support member having a body portion including a plurality of recesses longitudinally spaced from one another (405); positioning a flex circuit around the support member such that the flex circuit is radially spaced from the body portion of the support member (410); and filling a space between the flex circuit and the support member with a backing material through the plurality of recesses of the body portion (420). In one embodiment, an intravascular imaging device includes a flexible elongate member; an imaging assembly including: a flex circuit; and a support member (330) around which the flex circuit is disposed, the support member having a body portion including plurality of recesses (339), wherein the support member defines lumen in fluid communication with a space between the flex circuit and the support member via the plurality of recesses.

Abstract: A catheter assembly for locating an object of interest (e.g., an anatomical region such as a muscle, nerve bundle, etc.) is provided. The catheter assembly includes a catheter having a catheter body defining a proximal end and a distal end; a transducer located at the distal end of the catheter; one or more transducer wires extending from a proximal end of the transducer towards the proximal end of the catheter; and a length of tubing surrounding the catheter, the transducer, and the one or more transducer wires, wherein the length of tubing has a proximal portion and a distal portion, wherein the proximal portion surrounds the one or more transducer wires and the distal portion surrounds the transducer, wherein the proximal portion includes a conductive filler.

Abstract: In an ultrasound automatic scanning system according to an embodiment, one or more ultrasound probes transmit and receive an ultrasound wave. A mechanical mechanism holds the ultrasound probe and moves the ultrasound probe while a surface of the ultrasound probe is directed toward a subject. Processing circuitry detects, based on the ultrasound wave, distance information between a body surface and the surface of the ultrasound probe, with respect to a first scan position and a second scan position set along the body surface. The processing circuitry controls ultrasound scans performed in the first scan position and in the second scan position by the ultrasound probe moved by the mechanical mechanism based on the distance information. The processing circuitry controls the mechanical mechanism so as to move the ultrasound probe to the second scan position after the distance information detection and the ultrasound scan in the first scan position are performed.

Abstract: Diagnostic apparatus includes a plurality of antennas, which are configured to be disposed at different, respective locations on a thorax of a living body so as to direct radio frequency (RF) electromagnetic waves from different, respective directions toward a heart in the body and to output RF signals responsively to the waves that are scattered from the heart. Processing circuitry is configured to process the RF signals over time so as to provide a multi-dimensional measurement of a movement of the heart.

Abstract: The medical toilet may include a seat, lid, and bowl as does a traditional toilet. It also includes one or more acoustic transducers. The acoustic transducers may be located on the seat where they may measure bone density in a user's pelvis or femur. The acoustic transducers may be located on the lid or on a belt which wraps around the user. These acoustic transducers may collect data relating to a user's heart, lungs, liver, bowel, or other internal organs. The medical toilet may include a handrail with an acoustic transducer which measures the bone density in the user's wrist, radius, or ulna. A controller associated with the medical toilet may store algorithms for analyzing the data collected by the acoustic transducers. The controller may perform machine learning to improve the analyses and may calculate trends in repeated measurements taken from the same user or a population of users.

Abstract: A catheter and catheter system includes a first lumen and a second lumen adjacent to the first lumen. The catheter occupies an arc around the first lumen, wherein the arc is greater than 180° and less than 360°, thus creating a lengthwise opening to the first lumen. The catheter material surrounds the second lumen in a cross-sectional dimension. Prior to a procedure, a sampling device is introduced into the second lumen prior and the probe is snapped into the first lumen prior to insertion into an endoscope.

Abstract: Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic and ultrasound modalities. In some embodiments, a medical sensing system includes one or more external optical emitters and a measurement apparatus configured to be placed within a vascular pathway. The measurement apparatus may include a sensor array comprising sensors of two or more types. The sensors may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, and transmit and receive ultrasound signals. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.

Abstract: Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic and ultrasound modalities. In some embodiments, a medical sensing system includes one or more optical emitters and a measurement apparatus configured to be placed within a vascular pathway. The measurement apparatus may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, and transmit and receive ultrasound signals. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.

Abstract: An ultrasonic medical monitoring device may include: at least one ultrasonic probe that scans a test subject to acquire an echo signal; a blood pressure measuring device that measures a blood pressure parameter of a peripheral artery of the test subject; a processor configured to receive the echo signal and process the echo signal to obtain a blood flow parameter, and to calculate a myocardial mechanic parameter that represents a synchronous coupling of a circulatory system of left ventricle-aorta-peripheral arteries circulation according to the blood flow parameter and the blood pressure parameter; and a display device that is coupled to the processor and displays the myocardial mechanic parameter.

Abstract: Disclosed is an ultrasonic probe having an improved heat radiation capability. The ultrasonic probe includes a transducer module configured to transmit and receive an ultrasonic signal, a housing configured to accommodate the transducer module, a cable connected to the transducer module inside the housing and drawn from the inside of the housing to the outside of the housing through an end of the housing, a bending device configured to cover the cable and connected to the end of the housing to receive heat, a strain relief configured to surround the bending device and including a heat radiation groove extending along a circumferential direction of the cable, and a heat radiation fin inserted into the heat radiation groove such that one end thereof is in contact with the bending device and the other end thereof is in contact with outside air.

Abstract: A wireless handheld ultrasound system an ultrasound front end to transmit ultrasonic waves into a subject and convert received ultrasonic echoes into digital data; an image processor coupled to the ultrasound front end to convert the digital data into an image; and a power section coupled to the ultrasound front end and the image processor. The power section may include a battery; a charging circuit to charge the battery; and a wireless power transducer coupled to the charging circuit to convert wireless power received from an external source into electrical energy for the charging circuit.

Abstract: A plurality of opening positions is determined along a ? direction which is a curved direction on a two-dimensional transducer element array. Transmission openings are sequentially set to the plurality of opening positions. Transmission beam deflection scanning is performed at each opening position using the transmission openings. Transmission beam lines radiating from the center of the transmission opening are thus formed. A transmission apodization is applied before and after switching from one opening position to another so that there are no steps in the transmission sound field.

Abstract: The present disclosure describes ultrasound imaging systems and methods configured to identify and remove image artefacts from ultrasound image frames by applying a neural network to the frames. Systems may include an ultrasound transducer configured to acquire echo signals responsive to ultrasound pulses transmitted toward a target region. One or more processors communicatively coupled with the ultrasound transducer may be configured to generate an image frame from the ultrasound echoes and apply a neural network to the image frame. The neural network determines whether an artefact is present in the image frame, and identifies the type of artefact detected. The processors can also generate an indicator conveying the presence of the artefact, which can be displayed on a user interface. The processors can further generate an instruction for adjusting the ultrasound transducer based on the presence and type of artefact present within the image frame.

Abstract: Provided is a method of controlling a ultrasound diagnostic apparatus, in which a plurality of tracking pulses are transmitted at preset intervals to observe a shear wave induced in a region of interest (ROI) of an object, multi-reception scan lines corresponding to each of the tracking pulses are set, and signal processing is selectively performed on the multi-reception scan lines.

Abstract: Changes in tissue stiffness have long been associated with disease. Systems and methods for determining the stiffness of tissues using ultrasonography may include a device for inducing a propagating shear wave in tissue and tracking the speed of propagation, which is directly related to tissue stiffness and density. The speed of a propagating shear wave may be detected by imaging a tissue at a high frame rate and detecting the propagating wave as a perturbance in successive image frames relative to a baseline image of the tissue in an undisturbed state. In some embodiments, sufficiently high frame rates may be achieved by using a ping-based ultrasound imaging technique in which unfocused omni-directional pings are transmitted (in an imaging plane or in a hemisphere) into a region of interest. Receiving echoes of the omnidirectional pings with multiple receive apertures allows for substantially improved lateral resolution.

Abstract: The present invention relates to an ultrasound imaging system comprising: an image processor configured to receive at least one set of volume data resulting from a three-dimensional ultrasound scan of a body and to provide corresponding display data, an anatomy detector configured to detect a position and orientation of an anatomical object of interest within the at least one set of volume data, a slice generator for generating a plurality of two-dimensional slices from the at least one set of volume data, wherein said slice generator is configured to define respective slice locations based on the results of the anatomy detector for the anatomical object of interest so as to obtain a set of two-dimensional standard views of the anatomical object of interest, wherein the slice generator is further configured to define for each two-dimensional standard view which anatomical features of the anatomical object of interest are expected to be contained, and an evaluation unit for evaluating a quality factor for e

Abstract: A system and method include storage of an echo signal power spectrum of a reference phantom for a fundamental frequency band and an echo signal power spectrum of the reference phantom for a harmonic frequency band, acquisition of an echo signal power spectrum of a region of tissue for the fundamental frequency band and an echo signal power spectrum of the region of tissue for the harmonic frequency band, determination of a first backscatter coefficient based on the echo signal power spectrum of the region of tissue for the fundamental frequency band and the echo signal power spectrum of the reference phantom for the fundamental frequency band, determination of a second backscatter coefficient based on the echo signal power spectrum of the region of tissue for the harmonic frequency band and the echo signal power spectrum of the reference phantom for the harmonic frequency band, and determination of a non-linearity of the region of tissue based on the first backscatter coefficient and the second backscatter co

Abstract: Systems and methods for using quantitative ultrasound (“QUS”) techniques to generate imaging biomarkers that can be used to assess a prediction of tumor response to different chemotherapy treatment regimens are provided. For instance, the imaging biomarkers can be used to subtype tumors that have resistance to certain chemotherapy regimens prior to drug exposure. These imaging biomarkers can therefore be useful for predicting tumor response and for assessing the prognostic value of particular treatment regimens.

Abstract: Provided is an ultrasound imaging apparatus including: an ultrasound probe including a transducer module including an ultrasound transducer array, a driving device configured to rotate the transducer module, a magnet configured to rotate as a result of rotation of the transducer module, and a position sensor configured to output one of a first signal and a second signal on the basis of a change in magnetic flux density according to rotation of the magnet; and a controller configured to determine a first time for which the first signal is output as the transducer module rotates in a first direction, control the driving device to switch the rotating direction of the transduce module from the first direction to a second direction at a first switching time point at which an output signal is switched from the first signal to the second signal, control the driving device to switch the rotating direction of the transducer module one or more times during a time corresponding to the first time with respect to a second