Abstract: Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.

Abstract: An information processing apparatus is described. This determines a physiological parameter of an individual, the apparatus comprising: image circuitry configured to obtain a series of images of a skin exposed region of the individual; and processing circuitry configured to perform a periodogram on at least one of the red, green and blue channels of the skin exposed region of the series of images to obtain frequency components of the channel; and to determine the physiological parameter based on the periodogram.

Abstract: A method and apparatus for estimating heart rate of a subject from a video image of the subject. Regions of interest are generated by: detecting and tracking feature points through the video image sequence, triangulating the feature points and generating square regions of interest corresponding to the in-circles of the triangles; or, according to size and location probability distributions which are defined to have a high probability for image areas away from strong intensity gradients and which generate good quality signals. In an alternative embodiment, the intensity variations from the square regions of interest through the frame sequence are taken as time series signals and those signals which have a strong peak in the power spectrum are selected and subject to principal component analysis. The principal component with a highest signal quality is selected and its frequency is found and used to estimate the heart rate.

Abstract: A device comprising a piece of planar substrate embedded with two sensors and two emitters. The substrate has a generally planar surface for application onto the wearer's body part. The emitters and sensors are shown to be arranged in such a way that no subset of any two emitters and one sensor, or subset of any two emitters and one sensor, forms a straight line, which prevents the two sensors from detecting the same noise caused by the same wearer movements.

Abstract: A method for determining a heart rate (HR) using an infrared rays (IR) sensor and an electronic device is provided. An image is received using an IR sensor, at least one region of interest (ROI) for measuring the HR is determined in the received image, and the HR is determined based on the at least one determined ROI.

Abstract: The disclosed subject matter related to methods and apparatus for determining brain swelling in a patient as well as predicting an increase in intracranial pressure in the patient. The apparatus can include a transducer such as an ultrasound transducer communicatively connected to a controller via wires or via wireless communications device(s). A monitor and/or alarm device can be provided to notify a practitioner when the controller has determined brain swelling is occurring and/or when an imminent increase in intracranial pressure is likely to occur.

Abstract: An optrode may provide a cylindrical substrate with two or more electrodes deposited on said cylindrical substrate. The cylindrical substrate and electrodes may be coated by an insulating layer with openings or vias over certain portions of the electrodes that may provide a contact for the neural probe or may be utilized to connect lead lines. Manufacturing of an optrode may utilize a jig that secures a cylindrical substrate coated by a conductive material and a resist. A first mask may be positioned in an opening provided by the jig, and the cylindrical substrate may expose ions or neutral particles to define one or more electrode patterns. After regions of the resist and conductive material are removed to form the electrodes, a second mask may be utilized to define via regions in which portions of the electrodes are exposed and uncoated by an insulating layer.

Abstract: One or more non-transitory computer-readable media have instructions executable by a processor and programmed to perform a method. The method includes analyzing the electrical data to locate one or more wave front lines over a given time interval. The electrical data represents electrophysiological signals distributed across a cardiac envelope for one or more time intervals. A respective trajectory is determined for each wave end of each wave front line that is located across the cardiac envelope over the given time interval. A set of connected trajectories are identified based on a duration that the trajectories are connected to each other by a respective wave front line during the given time interval. A connectivity association is characterized for the trajectories in the set of connected trajectories.

Abstract: An extended wear electrocardiography patch is provided. A flexible backing includes an elongated strip of stretchable material. An electrocardiographic electrode is respectively affixed to and conductively exposed on each end of the elongated strip. A flexible circuit is affixed on each end to the elongated strip and includes a pair of circuit traces each originating within one of the ends of the elongated strip and coupled to one of the electrocardiographic electrodes. A non-conductive receptacle securely adhered on the one end of the elongated strip and includes electrode terminals aligned to interface the pair of circuit traces to an electrocardiography monitor to obtain electrocardiographic signals through the electrocardiographic electrodes.

Abstract: A catheter for use in a patient's heart, especially for mapping a tubular region of the heart, has a catheter body, a deflectable intermediate section and a distal mapping assembly that has a generally circular portion adapted to sit on or in a tubular region of the heart. A control handle of the catheter allows for single-handed manipulation of various control mechanisms that can deflect the intermediate section and contract the mapping assembly by means of a deflection control assembly and a rotational control assembly. The deflection control assembly has a deflection arm and a rocker member. The rotational control assembly has an outer rotational member, an inner rotational member and a cam. A pair of puller members are responsive to the deflection control assembly to bi-directionally deflect the intermediate section. A third puller member is responsive to the rotational control assembly to contract the generally circular portion of the mapping assembly.

Abstract: Multiple circuits in a computing device can share one or more conductive elements. The use of the conductive element can vary by circuit, such as an antenna radiator for a radio frequency (RF) circuit or an electrode for an electrocardiography (ECG) circuit. The circuitry sharing a conductive element can utilize signals obtained over different frequency ranges. Those ranges can be used to select decoupling circuitry, or elements, that can enable the respective circuits to obtain signals over a respective frequency range, excluding signals over one or more other frequency ranges corresponding to other circuitry sharing the circuit. Such an approach allows for concurrent independent operation of the circuitry sharing a conductive element.

Abstract: Electrooculogram (EOG) detection methods and EOG detection apparatuses are described. The EOG detection method can comprise: acquiring at least one EOG signal of a blink of at least one eye of a user; and analyzing the at least one EOG signal to determine whether the blink is a protective blink. A basis is thus provided for further applications of an eye movement detection technology by determining, according to an EOG signal of a user, whether a blink of the user is a protective blink.

Abstract: An apparatus includes an interface and a processor. The interface is configured to receive signals from a calibration probe inserted in an organ of a patient. The processor is configured to hold multiple electrode positions corresponding respectively to multiple electrodes attached externally to the patient, to evaluate, based on the received signals, multiple data points, each data point including (i) a respective measured coordinate of the calibration probe, and (ii) a respective set of electrical values indicative of respective impedances between the calibration probe and the multiple electrodes. The processor is further configured to evaluate, based on the multiple data points and on the electrode positions, an alternative position for a selected electrode to be repositioned, and to output an identification of the selected electrode and the evaluated alternative position.

Abstract: The present invention provides a system and method for multi-phase flow decomposition using electrical capacitance imaging techniques. The present invention provides a system and method to obtain permittivity distributions at a plurality of frequency markers using volume tomography image reconstruction to determine volume fraction of each phase and to produce images of the volume fraction for each phase.

Abstract: Characterizing myocardial perfusion pathology includes analyzing a plurality of medical images of at least a portion of the heart of a subject of interest (20), acquired in a consecutive manner by a medical imaging modality (10). Intensities of selected myocardial image positions from the plurality of medical images are sampled and assigned an index representing an order of acquisition to the respective sampled intensities of the myocardial image positions to obtain intensity curves (60). An index number (64, 66) indicative of a spatio-temporal perfusion inhomogeneity or perfusion dephasing among at least a subset of myocardial segments of the plurality of myocardial segments is calculated, based on the obtained intensity curves (60).

Abstract: Described herein is a system and method of controlling real-time image-guided adaptive radiation treatment of at least a portion of a region of a patient. The computer-implemented method comprises obtaining a plurality of real-time image data corresponding to 2-dimensional (2D) magnetic resonance imaging (MRI) images including at least a portion of the region, performing 2D motion field estimation on the plurality of image data, approximating a 3-dimensional (3D) motion field estimation, including applying a conversion model to the 2D motion field estimation, determining at least one real-time change of at least a portion of the region based on the approximated 3D motion field estimation, and controlling the treatment of at least a portion of the region using the determined at least one change.

Abstract: The invention relates to a method for determining the position of a surgical tool relative to a target volume inside an animal body according to a pre-plan comprising the steps of i) obtaining a plurality of two-dimensional images of said target volume using imaging means, each 2D-image being represented by an image data slice I(x,y,z); ii) reconstructing from said plurality of image data slices I(x,y,z) a three-dimensional image of said target volume using transformation means, said 3D-image being represented by a volumetric image data array V(x,y,z); iii) displaying said three-dimensional image of said target volume to an user using displaying means.

Abstract: A system and method for detecting, timing, and adapting to patient motion during an MR scan includes using the inconsistencies between calculated images from different coil-array elements to detect the presence of patient motion and, together with the k-space scan-order information, determine the timing of the motion during the scan. Once the timing is known, various actions may be taken, including restarting the scan, reacquiring those portions of k-space acquired before the movement, or correcting for the motion using the existing data and reconstructing a motion-corrected image from the data.

Abstract: Various embodiments of an intubation system include a tracheal tube and an illumination assembly that is removably couplable to a tubular body of the tracheal tube. The tracheal tube may be a double lumen tracheal tube having a first cuff that is adapted to be inflated to seal against the walls of a patient's trachea and a second cuff that is adapted to be inflated to seal against the walls of the patient's bronchial stem. The illumination assembly may have one or more illumination devices that are adapted to produce light within the patient's trachea, the patient's bronchial stem, or both when the illumination assembly is coupled to the tubular body.

Abstract: A method of evaluating airway wall density and inflammation including: segmenting a bronchial tree to create an airway wall map; for each branch, taking a set of locations that form the wall of each branch from the map and sampling the value in a virtual non-contrast image of the bronchial tree and, given a set of samples of pre-contrast densities, computing a value to yield a bronchial wall density for each branch to yield density measures; for each branch, taking the set of locations that form the wall of each branch from the map and sampling the value in a contrast agent map of the bronchial tree and, given the set of samples of contrast agent intake, computing a value to yield a bronchial wall uptake for each branch to yield inflammation measures; and using the density and inflammation measures to determine treatment or predict outcome for a patient.

Abstract: A single sensor capable of detecting both airflow in spirometry and the full range of sound frequencies needed to track clinically relevant breath sounds is provided. The airflow sensor includes a movable flap with one or more integrated strain gauges for measuring displacement and vibration. The airflow sensor is inherently bidirectional. The sensor is an elastic flap airflow sensor that is capable of detecting data needed for both spirometry and auscultation measurements. The sensor is sterilizable and designed for the measurement of human respiratory airflow. The sterilizable sensor is also suitable for non-medical fluid flow metering applications. Additional devices such as sensors for the ambient level of various chemicals, sensors for temperature, sensors for humidity and microphones, may be affixed to the flap. When the strain gauge is placed in a conventional Wheatstone bridge configuration, the sensor can provide the airflow measurements needed for medical spirometry.

Abstract: A wearable system and method for providing BCG data from a user including a wearable sensor configured to receive cardiogenic surface vibration waveforms, a calibrating sensor configured to receive cardiogenic center-of-mass (COM) vibration waveforms, and a processor configured to use the COM vibration waveforms as a template for modifying the surface vibration waveforms to provide health-related outputs. A systematic approach for elucidating the relationship between surface vibrations of the body in the head-to-foot direction from the wearable sensor, and the movements of the whole body as measured by the calibrating sensor is disclosed. Additionally, a methodology for converting the wearable acceleration signals to BCG signals such that the same analysis and interpretation tools can be used for both measurements is presented.

Abstract: Wearable devices and methods of using the same for inputting ambient conditions and the movement and bio-signals of a user to an external device are provided. The wearable device can include a finger sensor and a wrist sensor, wherein each includes an accelerometer, a gyroscope, and a compass. The compass can be a magnetometer. The wrist sensor can also include a power source, a computer, and a touchscreen.

Abstract: An orthodontic system and method for moving and aligning at least one tooth of a set of teeth of at least one of an upper jaw and a lower jaw of a patient. In the system and method an orthodontic appliance can be provided which may include a force exerting member for applying a force to and moving the at least one tooth, a tooth movement sensor member for obtaining at least one of tooth movement data, tooth position data, and tooth identification data, and a tooth movement monitor for calculating at least one of an amount of tooth movement and tooth position from the at least one of the tooth movement data, the tooth position data, and the tooth identification data obtained with the tooth movement sensor arrangement.

Abstract: A notification system is provided that provides notification of patient events such as movement and/or incontinence. The notification system provides for a plurality of different pressure sensor pads as well as an incontinence pad to be used in association with a single monitor.

Abstract: An action recognition system is illustrated. The action recognition system has an annular body, at least one light emitting unit, at least one light sensing unit and an action recognition module. The annular body is worn on a movable part of a user. One end of the light emitting unit is exposed on an inner side of the annular body, wherein the light emitting unit emits a first light beam illuminating at least a portion of the movable part. One end of the light sensing unit is exposed on the inner side of the annular body. The light sensing unit operatively senses a second light beam reflected by the at least portion of the movable part and generates a light sensing signal. The action recognition module is configured to operatively determine an action of the user according to the light sensing signal.

Abstract: Techniques for user identification by a biometric monitoring device are disclosed. In one aspect, a method of operating a biometric monitoring device may involve measuring a weight of a user in response to detecting that the user is standing on a platform, determining, based on sensor data generated by a sensor, a user parameter indicative of the user's identification, identifying one of a plurality of user profiles as corresponding to the user based on a comparison of the user parameter to parameter values and a comparison of the measured weight of the user to weight values, and updating the identified user profile based on at least one of the measured weight and the user parameter.

Abstract: A method of enhancing an audio signal from an audio output device is provided. For a frequency band, a user masking contour curve covering at least a part of said frequency band is obtained, a target masking contour curve is derived from the user masking contour curve, and a multi-band digital compression system is parameterized based on the sound level of the target masking contour curve at a given frequency and the sound level of the user masking contour curve at the same given frequency. The obtained parameters are outputted to provide an enhanced audio signal.

Abstract: Speech understanding in the presence of background noise can be assessed using novel hearing tests. One such test is a Masking Level Difference with Digits (MLDD) test, which is a clinical tool designed to measure auditory factors that influence the understanding of speech presented within a background of noise. The MLDD test can be used clinically to facilitate a determination of functional hearing. The MLDD test presents background noise using both monotic and diotic conditions.

Abstract: Generally, methods, devices, and systems related to analyte monitoring and data logging are provided—e.g., as related to in vivo analyte monitoring devices and systems. In some aspects, methods, devices, and systems are provided that relate to enable related settings based on an expected use of an in vivo positioned sensor; logging or otherwise recording analyte levels acquired or derived—e.g., sample analyte levels more frequently than they are logged or otherwise recorded in memory; dynamically adjust the data logging frequency; randomly determine times of acquiring or storing analyte levels from the in-vivo positioned analyte sensors; and enable recording related settings when the system is operable.

Abstract: A sensor is provided for measuring a dissolved oxygen concentration in vivo when implanted at a tissue site and in ex vivo applications. The sensor includes an article comprising a sensing medium retained within the implantable article by an oxygen-permeable material. The sensing medium comprises an MR contrast agent for oxygen. The sensor is configured to indicate the dissolved oxygen concentration of a fluid, e.g., in vivo at the tissue site, when subjected to an MR-based method.

Abstract: A kit for determining a concentration of an analyte in a body fluid is disclosed, the kit comprising: a) a sensor module comprising i. a sensor adapted to determine the concentration; ii. a control device connected to the sensor comprising a data collection device to collect measurement data acquired by the sensor, the control device further comprising a wireless near-field communication device adapted to transmit measurement data, the sensor module comprising a sensor module mechanical interface; b) a data reader module adapted to receive measurement data transmitted by the sensor module via wireless near-field communication, the data reader module comprising at least one data storage device; c) a data transmission module to receive measurement data transmitted by the sensor module via wireless near-field communication, the data transmission module comprising a wireless far-field communication device to transmit the measurement data to an external device.

Abstract: The concentration of substance in blood is measured non-invasively, with high accuracy and with simple configuration. Laser light generated by a light source is locally irradiated on the body epithelium of a subject, and the resulting diffused reflected light is detected by a light detector. The laser light has a wavelength of 9.26 ?m. The laser light is generated by converting and amplifying pulsed excitation light from an excitation light source to a long wavelength. A plate-shaped window that is transparent to mid-infrared light is brought in close contact with the body epithelium. The glucose concentration in interstitial fluid can be calculated using normalized light intensity calculated from a signal ratio of signals from a monitoring light detector and light detector.

Abstract: A device includes a housing, an emitter, a detector, and a processor. The housing has a body contact surface. The emitter is coupled to the housing and has an emission surface and has an electrical terminal. The emission surface is configured to emit light proximate the body contact surface in response to a signal applied to the electrical terminal. The detector is coupled to the housing. The detector has a sense surface and an output terminal. The detector is configured to provide an output signal on the output terminal in response to light detected at the sensor surface. The processor is configured to implement an algorithm to determine a tissue site based on the emitted light and based on the detected light.

Abstract: A medical device and method of making the medical device are disclosed. The medical device includes a sensor having an interconnect. The interconnect has a first conductive layer, an insulation layer, and a second conductive layer separated from the first conductive layer by the insulation layer. An electrical contact is provided that is electrically connected to the second conductive layer and is contactable from the side of the interconnect that opposes the second conductive layer. The electrical contact is provided free of micro-vias. The medical device also includes an electronics assembly having an electrical connector, the electronics assembly configured to mate with the interconnect to establish an electrical connection between the electrical connector and the first conductive layer via the electrical contact.

Abstract: Methods and apparatus to identify an emotion evoked by media are disclosed. An example apparatus includes a synthesizer to generate a first synthesized sample based on a pre-verbal utterance associated with a first emotion. A feature extractor is to identify a first value of a first feature of the first synthesized sample. The feature extractor to identify a second value of the first feature of first media evoking an unknown emotion. A classification engine is to create a model based on the first feature. The model is to establish a relationship between the first value of the first feature and the first emotion. The classification engine is to identify the first media as evoking the first emotion when the model indicates that the second value corresponds to the first value.

Abstract: An electronic device for providing biometric information is provided. The electronic device includes a sensor module, a memory, and a processor electrically connected to the sensor module and the memory. The processor obtains a biometric signal from the sensor module at a predetermined time interval, determines whether a user is in a first state on the basis of the obtained biometric signal, in case the user is in a first state, obtains a representative value for a respective of the at least one biometric signal, defines the obtained representative value for the respective of the at least one biometric signal as a candidate reference value for a corresponding biometric signal, determines a candidate reference value satisfying a predetermined condition as a first reference value for the corresponding biometric signal, and updates a second reference value previously configured for the corresponding biometric signal on the basis of the first reference value.

Abstract: A system and method for health diagnostics and more specifically to an image-capture based system and method for detecting physiological state for a subject. The system provides a remote and non-invasive approach by which to detect physiological state with a high confidence. The system enables monitoring of hemoglobin concentration changes by optical imaging and related detection systems.

Abstract: In an embodiment of the subject matter described herein a system is provided. The system includes a portable host system having one or more processors and a memory for storing a plurality of applications. The one or more processors configured to execute programmed instructions of a select application by performing one or more operations, which include obtain a set of frames of 2D ultrasound images, develop a prospect model indicating a likelihood that frames within the set include an organ of interest (OOI), identify primary and secondary reference frames from the set of the frames based on the prospect model, determine a characteristic of interest in the primary reference frame, select a candidate shape for the OOI based on the character of interest in the primary reference frame, and adjust the candidate shape based on the secondary reference frames to form a resultant shape for the OOI.

Abstract: A region extraction unit extracts a bone region and a cartilage region from a three-dimensional image. A projection direction determination unit determines a projection direction of the cartilage region and a projection image generation unit projects the bone region and the cartilage region in the determined projection direction and generates a projection image. A quantification unit calculates a quantitative value of the cartilage region on the projection image.

Abstract: A computer-implemented method of assessing whether a patent has a condition is provided, including generating a facial landmark on a received input video to define points associated with a region of interest on a face of the patient, defining a period of talking based respective positions of the defined points, during the period of talking, measuring pause frequency, repetitive pattern, and vocabulary variety, without determining or applying semantic information associated with the talking, to generate an aggregate score, and based on the aggregate score, generating a prediction of the patient having the condition associated with the aggregate score.

Abstract: In an information processing method, a computer acquires a sleep state of a person existing in space, acquires detection data output from a sensor that detects entry of an object into the space, performs a first determination to determine whether or not the sleep state changes to awakening within a predetermined time from a time point at which the object is estimated to enter the space based on the sleep state and the detection data, generates, in association with the sleep state before the time point, awakening information for determining possibility that the person is awakened by entry of the object in a case where the person is in the sleep state before the time point of entry based on a result of the first determination, and presents the awakening information associated with the sleep state via a presentation device.

Abstract: Disclosed is a pain detection system and method. Preferred methods include capturing imaging data from patient using functional near-infrared spectroscopy. In methods of the invention, pain may be assessed from a non-responsive patient. Preferred methods may further include measuring hemodynamic parameters using the optical imaging data and averaging the measured hemodynamic parameters to reduce background noise. Additionally, a pattern in the averaged hemodynamic parameters is identified and the pattern is compared to a predetermined associated with patient pain. The method further includes detecting, by the processor, a similarity between the pattern and the predetermined pattern and outputting a signal indicating patient pain.

Abstract: Systems and methods for delivering a drug with a tracer or contrast agent are disclosed herein, as are systems and methods that generally involve CED devices with various features for reducing or preventing backflow. In some embodiments, CED devices include a tissue-receiving space disposed proximal to a distal fluid outlet. Tissue can be compressed into or pinched/pinned by the tissue-receiving space as the device is inserted into a target region of a patient, thereby forming a seal that reduces or prevents proximal backflow of fluid ejected from the outlet beyond the tissue-receiving space. In some embodiments, CED devices include a bullet-shaped nose proximal to a distal fluid outlet. The bullet-shaped nose forms a good seal with surrounding tissue and helps reduce or prevent backflow of infused fluid.

Abstract: A method, system, apparatus, and/or device for adjusting a power consumption level of a device. The method, system, apparatus, and/or device may include: a first sensor interface, a second sensor interface, and a processing device coupled to the first sensor interface and the second sensor interface. The processing device may: measure a first physiological measurement via the first sensor interface within a first period of time; measure a second physiological measurement via the second sensor interface within the first period of time; adjust a power consumption level of the apparatus in view of at least one of the first physiological measurement or the second physiological measurement; measure the physiological measurement via the first sensor interface at the adjusted power consumption level within a second period of time; and measure a second physiological measurement via the second sensor interface at the adjusted power consumption level within the second period of time.

Abstract: A method of measuring patient position by a patient monitoring system includes providing a first position sensor attachable to a portion of the patient, and providing a hub device that includes a calibration position sensor. A first calibration position measurement is received from the calibration position sensor while the hub device is aligned with the portion of the patient where the first position sensor is attached. A first patient position measurement is received from the first position sensor, and then a calibration map is determined for the first position sensor based on a difference between the first calibration position measurement and the first patient position measurement. Position measurement data is then received from the first position sensor, and a patient position is determined based on the position measurement data and the calibration map.

Abstract: A system for detecting bioelectrical signals of a user comprising: a set of sensors configured to detect bioelectrical signals from the user, each sensor in the set of sensors configured to provide non-polarizable contact at the body of the user; an electronics subsystem comprising a power module configured to distribute power to the system and a signal processing module configured to receive signals from the set of sensors; a set of sensor interfaces coupling the set of sensors to the electronics subsystem and configured to facilitate noise isolation within the system; and a housing coupled to the electronics subsystem, wherein the housing facilitates coupling of the system to a head region of the user.

Abstract: A wearable medical device is provided. The wearable medical device includes a garment that includes a sensing electrode, at least one of an inductive element and a capacitive element included in at least part of the garment, and a controller. The controller may be configured to determine a confidence level of information received from the sensing electrode based on at least one of an inductance of the inductive element and a capacitance of the capacitive element.

Abstract: A method for clip selection includes receiving through an interface to a medical imaging device, a selection of a diagnostic procedure and a target portion of a mammalian body. Thereafter, the device acquires video clip imagery of the target portion and stores the video clip imagery in an image store. Each video clip of the video clip imagery is then image processed to determine a view and a quality of each video clip and a rule is retrieved from a rules base corresponding to the selected diagnostic procedure and target portion. In this regard, the rule specifies a requisite view and quality of the video clip imagery. Finally, the retrieved rule is applied to the video clip imagery as a filter to produce a subset of video clip imagery satisfying the specified requisite view and quality and the subset of video clip imagery is stored in the image store.

Abstract: An adaptive controller used in a photoplethysmography sensing system, comprises a plurality of hardware circuits which are configured to: receive a photoplethysmography signal (hereinafter, “PPG signal”) processed; determine whether the PPG signal processed satisfies with a requirement; output the PPG signal processed if the PPG signal processed satisfies with a requirement; and adjust a gain of an amplifier for amplifying the PPG signal and/or a driving signal of a light source if the PPG signal processed does not satisfy with a requirement.