Abstract: The present disclosure relates to a method and a system for collecting and managing terminal use pattern information generated during a process of controlling screen display of a user terminal for eye protection and management. The method, according to the present disclosure, comprises the steps of: measuring a distance between a user terminal and a user; measuring a use time of the user terminal; converting and processing image information displayed on a screen of the user terminal by a predetermined image processing method, when the distance and/or the use time satisfy/satisfies a predetermined condition; and collecting terminal use pattern information comprising at least one of image conversion processing information, distance, and use time when a predetermined reaction is sensed from a user.

Abstract: A method of identifying individuals impaired by a psychoactive substance such as cannabis. The method includes presenting monocularly to a subject being tested; to each eye separately, a sinusoidal grating pattern of fixed spatial frequency with achromatic contrast or color contrast between grating stripes being temporally alternately modulated at a temporal frequency that ranges between 10 Hz and 60 Hz with a pattern of the contrast being such that the subject being tested can see a frequency doubling in the grating pattern.

Abstract: An ophthalmologic apparatus includes: an objective lens that faces a subject's eye; a first illumination optical system that irradiates a cornea of the subject's eye with illumination light; and a corneal measurement optical system having an imaging element that takes an image of a corneal reflection light, which is a reflection of the illumination light, through the objective lens, and outputs an imaging signal. The corneal measurement optical system includes a first mirror arranged near the objective lens and a second mirror arranged near the imaging element. The first and second mirrors and are configured such that the corneal reflection light that enters and is reflected from the first mirror, and then enters and is reflected from the second mirror exits toward an incident side from which the corneal reflection light enters a reflection surface of the first mirror.

Abstract: An ophthalmologic apparatus includes: an ophthalmologic apparatus body having: an objective lens that faces a subject's eye; a first illumination optical system that irradiates a cornea of the subject's eye with illumination light emitted from a first illumination light source along an optical axis overlapping an optical axis center of the objective lens; an interference image capturing camera that takes an image of a corneal reflection light through the objective lens and outputs an imaging signal; and a calculation unit that calculates, based on a corneal reflection image, of a corneal reflection light, input from the interference image capturing camera, a thickness of a tear fluid film at each position on the corneal surface; and a guide rail that supports the ophthalmologic apparatus body.

Abstract: A method for determining thickness of layers of the tear film includes reconstructing a full- or hyper-spectral interference pattern from an imaged multi-spectral pattern. Tear film thickness can then be estimated from the full- or hyper-spectral interference pattern. Using a full- or hyper-spectral interference pattern provides a greater number of frequency sampling points for increased tear film thickness estimation accuracy, without traditional time consuming techniques.

Abstract: Disclosed are an electronic device and a method for determining a degree of conjunctival hyperemia using the same. The electronic device includes a camera and a processor configured to acquire an image including an eye captured by the camera, identify one or more blood vessels included in the image, and determine a degree of conjunctival hyperemia based on sizes of the identified one or more blood vessels.

Abstract: A system and method for determining eye surface contour using multifocal keratometry is disclosed. The system includes a light source, a light detector, a processor, a non-transitory machine-readable medium communicatively coupled to the processor, and instructions stored on the non-transitory machine-readable medium. The instructions, when loaded and executed by the processor, cause the processor to project a light, using the light source, onto a plurality of surfaces of an eye; create, using the light detector, an image of a plurality of reflections, each of the plurality of reflections created by reflecting the light off of one of the plurality of surfaces of the eye; determine that the plurality of reflections are in focus in the image; and calculate, based on the determination, a curvature of the plurality of surfaces of the eye based on the image.

Abstract: A system and method are provided for obtaining a pupil response profile for a subject. The method include: obtaining scan data as frames of a pupil response over time prior to, during and after exposure to a flash of a light source; locating a candidate pupil to be measured from the scan data; image processing the scan data to obtain a set of pupil candidate measurements to generate a graph of pupil measurements against time; filtering the graph to produce a final set of pupil measurements forming a pupil response profile. The method may also include: measuring profile parameters from the pupil response profile; and using the profile parameters to determine aspects of the pupil response.

Abstract: A patient support apparatus includes a first transceiver adapted to wirelessly communicate with a second transceiver of a headwall interface that is positioned off of the patient support apparatus. A communication link is automatically established between the first and second transceivers without requiring a user of the patient support apparatus to activate a designated control and without requiring the user to identify the headwall interface. The first transceiver includes a unique identifier assigned to the headwall interface in its messages to the headwall interface. The first transceiver may also automatically transmit a disconnect signal to the headwall interface indicating the termination of the communication link is not accidental. The disconnect signal is sent based on one or more of the following: (1) a brake being off, (2) an A/C power cord being unplugged; and/or (3) a signal strength between the transceivers decreasing.

Abstract: A device, system, and methods are provided for remotely monitoring pump equipment. A monitoring device is mechanically mounted to a pump. The monitoring device includes internal vibration, temperature, and location sensors to periodically monitor a pump and upload data samples via cellular connection to a provider network. The monitoring device additionally includes connections to external sensors that can be sampled and uploaded with the other data samples, when the monitoring device is connected to external power. Authenticated users access the pump data though a user device that connects to the provider network.

Abstract: In certain embodiments, the invention relates to systems and methods for in vivo tomographic imaging of fluorescent probes and/or bioluminescent reporters, wherein a fluorescent probe and a bioluminescent reporter are spatially co-localized (e.g., located at distances equivalent to or smaller than the scattering mean free path of light) in a diffusive medium (e.g., biological tissue). Measurements obtained from bioluminescent and fluorescent modalities are combined per methods described herein.

Abstract: In embodiments, a first 3D model of a patient's teeth based on first intraoral scan data taken at a first time is processed to recognize the teeth in the first 3D model. A second 3D model of the patient's teeth based on second intraoral scan data taken at a second time is processed to recognize the teeth in the second 3D model. The first 3D model is compared to the second 3D model and a plurality of AOIs in the second virtual 3D model representative of at least one of tooth wear, tooth breakage, tooth movement, gingival recession or gingival swelling are determined based on the comparison. The teeth recognized in the first 3D model are compared to the teeth recognized in the second 3D model, and one or more AOIs in the second virtual 3D model representative of tooth wear or tooth breakage are determined based on the comparison.

Abstract: An acoustic wave device includes an insertion object having a photoacoustic wave generator, a light source that irradiates the photoacoustic wave generator with light, an insertion object image signal generator that generates an insertion object image signal from a photoacoustic wave reception signal from the photoacoustic wave generator, and an insertion object display image signal generator that generates an insertion object display image signal having a center at a peak position where a signal strength of the insertion object image signal becomes a peak value, having a maximum width corresponding to a predetermined reference signal width, and having a signal strength corresponding to the peak value at the center.

Abstract: An ambulatory medical device comprises: a sensing component to be disposed on a patient for detecting a physiological signal of the patient; and monitoring and self-test circuitry configured for detecting a triggering event and initiating one or more self-tests based on detection of the triggering event. The ambulatory medical device senses the physiological signal of the patient substantially continuously over an extended period of time.

Abstract: A system for monitoring blood pressure includes an implantable medical device (IMD) and an external device (ED). The IMD senses an electrogram (EGM) signal, identifies a feature thereof indicative of a ventricular depolarization, and transmits a conductive communication signal through patient tissue indicating when the ventricular depolarization occurred. The ED is worn against skin and configured to receive the conductive communication signal. The ED is also configured to sense a plethysmography (PG) signal and identify a feature thereof indicative of when a pulse wave responsive to the ventricular depolarization reaches a region of the patient adjacent the ED, and determine a delay time (TD) indicative of how long it takes the pulse wave to travel from the patient's heart to the region of the patient adjacent to the ED. The TD is a surrogate of the patient's blood pressure and useful for monitoring the patient's blood pressure and/or changes therein.

Abstract: Some embodiments of a balloon catheter device for introduction into a body vessel, in particular the coronary sinus, can include a catheter shaft which carries an inflatable balloon on its distal portion and in which a plurality of different lumens are formed. In particular embodiments, a system for treating heart tissue can include a coronary sinus occlusion catheter configured for improved deliverability to the coronary sinus and for thereafter performing intermittent occlusion of the coronary sinus.

Abstract: A blood pressure measurement device includes an outer case; a base; a pump provided on the base such that the pump is shifted from a center of the outer case and located on one side as viewed in a circumferential direction of a living body; a drive unit provided on the base and located on one side of the pump as viewed in a direction orthogonal to the circumferential direction; an on-off valve provided on another side of the pump as viewed in the direction orthogonal to the circumferential direction; a pressure sensor provided on said another side of the pump as viewed in the direction orthogonal to the circumferential direction; and packing provided between the on-off valve and the pressure sensor and the base.

Abstract: Embodiments herein relate to systems, devices, and methods for assessing hemorrhage and other conditions and treating patients suffering from the same. In an embodiment, a method for detecting hemorrhage in a patient is included. The method can include obtaining a breath sample from the subject and contacting it with a chemical sensor element, the chemical sensor element including a plurality of discrete graphene varactors; sensing and storing capacitance of the discrete graphene varactors to obtain a sample data set; and classifying the sample data set into one or more preestablished hemorrhage classifications. Other embodiments are included herein.

Abstract: Systems and methods of arrhythmia detection and associated apparatus that utilize machine learning techniques that allow for the consideration individual characteristics and the tailoring/personalization of biometric data allow for early detection and treatment, especially of cardiac arrhythmias and other abnormalities.

Abstract: Provided are a computer system, a drug recommendation method and a program capable of prescribing an appropriate drug for treating an illness. The computer system for recommending a drug corresponding to a diagnosis result of the illness outputs inquiry data for inquiring a user, accepts response data regarding the inquiry data, performs a diagnose on basis of the response data, and learns the diagnosis and a type and dosage of a drug prescribed on basis of the diagnosis in advance and recommends a drug associated with the diagnosis on basis of a result of the learning. In addition to diagnosing, the computer system also learns the type and dosage of the drug on basis of physical condition data, medical history and medication history, etc., of the user in advance and recommends the drug. The computer system notifies a pharmacist capable of prescribing of the recommended drug.

Abstract: Pressure sensing layers, devices comprising same, pressure sensing monitors and composite materials comprising a) a porous matrix material comprising a siloxane polymer, comprising a closed porosity volume fraction, and, optionally, an open porosity volume fraction, and b) a conductive or semiconductive filler substantially present in said closed porosity volume fraction of said porous matrix material a), and films, coated substrates and multilayer structures comprising the composite material and the use thereof in pressure sensing devices.

Abstract: A method and system for analyzing two related physiological signals to determine a time difference between them. The fundamental frequency components are analyzed to determine a time difference. This approach is robust against varying and different wave 5 shapes, providing a stable and accurate determination of a time difference.

Abstract: An example of a digital artery blood pressure monitor may include a tactile sensor array disposed on an inner surface of a cuff, the tactile sensor array including a plurality of capacitive sensors to detect pressure changes within a digital artery of a finger due to blood flow, where the pressure changes cause changes to capacitance values of one or more capacitive sensors of the tactile sensor array, and control circuitry coupled to the tactile sensor array to receive the capacitance values from the tactile sensor array, and determine a blood pressure based on the capacitance values.

Abstract: A method of monitoring cardiac activity of a user is provided. Heart beat time data is detected by a PPG sensor (110) in a health sensor (100) worn by the user (1). Motion data is detected by a motion sensor (120) in the health sensor (100). The output data of the PPG sensor (110), which comprises heart beat time data, is analyzed to detect arrhythmia periods. The detected heart beat time data, the detected motion data and the detected arrhythmia are forwarded to an external device, where the data can be stored. The output data of the PPG sensor (110) comprising the heart beat time data, the detected motion data and the detected arrhythmia periods are displayed such that a medical professional (2) can analyze this data to determine whether a suspected arrhythmia period is valid.

Abstract: A biological information detection device includes: a video capture unit, a blood flow analysis unit, a local pulse wave detection unit, a pulse wave propagation velocity calculation unit, and a blood pressure estimation unit. The video capture unit obtains video information on a face of a living body. The blood flow analysis unit analyzes video data of at least three skin areas in the video information, as blood flow information. The local pulse wave detection unit is provided for each skin area to calculate pulse information based on the blood flow information sequenced chronologically. The pulse wave propagation velocity calculation unit calculates a pulse wave propagation velocity based on a phase difference between pieces of the pulse information at each skin area calculated by the local pulse wave detection unit. The blood pressure estimation unit estimates blood pressure based on the pulse wave propagation velocity.

Abstract: One embodiment is a method comprising collecting photoplethysmography (“PPG”) data associated with a user using a biometric monitoring device; extracting a signal quality metric (“SQM”) from the collected PPG data; classifying the PPG data signal based on the extracted SQM into one of a plurality of signal quality levels; and determining based on the classification whether to increase, decrease, or maintain a power level of an LED of the biometric monitoring device.

Abstract: Methods and systems for conditioning a signal indicative of electrosurgical unit activity are described. A hardware circuit acquires AC current from an electrosurgical unit on patient isolated circuitry and conditions the signal in either of two alternate processing methods. The processed signal is routed as input to an analog to digital converter circuit. A method for determining saturation on referential inputs and recovering inputs to an unsaturated state is also described.

Abstract: An inspection apparatus to inspect physiological information of a subject being tested includes: an input interface configured to receive a signal corresponding to the physiological information; a display configured to display information corresponding to the signal in real time during the inspection; a storage in which data corresponding to the information is stored; a communication interface communicatively connected to an external apparatus; and one or more processor configured to, when a request from the external apparatus is received by the communication interface, generate based on the data a data file for enabling browsing of the information and transmit the data file to the external apparatus via the communication interface.

Abstract: A system and a process are provided for evaluating subliminal pixel patterns and identifying trigger patterns, which are pixel patterns that trigger a response in subjects exposed to the pattern. Each pixel pattern is embedded in a digital video or a digital still image. Pixel patterns that are found to induce reactions in subjects are identified as trigger patterns and are flagged for re-testing. Re-tested trigger patterns that repeatably induce reactions are identified as positive trigger patterns and are studied further. Variations are made to a positive trigger pattern to determine whether small changes can affect how a subject responds when exposed to that positive trigger pattern. A positive trigger pattern is evaluated to determine whether it can induce an emotional, a physical, and/or a behavioral change in the subjects and, if so, the positive trigger pattern is applied to a real-world situation.

Abstract: Wearable ECG and auscultation monitoring system with SOS and remote monitoring. A wearable device for monitoring cardiac parameters of a user is provided. The device comprises a first electrode to measure electrical potential on a first portion of the user's body, a second electrode to measure electrical potential on a second portion of the user's body and a processor to measure the potential difference between the first electrode and the second electrode. It further comprises a sensor for capturing Seismocardiography, Phonocardiogramand Ballistocardiogram generated by the motion of the heart wall and the blood flow, display module for displaying the generated information, wireless communication modules for communicating and transferring the information generated by the device to a smart phone application of the user and to a remote data processing system.

Abstract: An apparatus includes data acquisition circuitry and a processor. The data acquisition circuitry is configured to acquire multiple signals using multiple respective electrodes of an array of electrodes coupled to one of an organ of a patient and tissue or a cell culture. The processor is configured to hold a definition of a mixed-norm that is defined as a function of relative positions of the electrodes in the array, and jointly compress the multiple signals in a compressed-sensing (CS) process that minimizes the mixed-norm.

Abstract: A time series data analysis method according to an embodiment of the inventive concept is performed by a computing device. The method includes inputting, for each of a plurality of units, into which the time series data is split on a time axis, a feature of each of the units to an intermediate neural network, obtaining m-dimensional intermediate output data (m is a natural number of 2 or more) from the intermediate neural network, inputting the intermediate output data of a plurality of units immediately adjacent in time to a final neural network to obtain final output data output from the final neural network, and generating an analysis result of the time series data using the final output data.

Abstract: An electrocardiogram analysis apparatus according to an embodiment of the present invention includes an inputter configured to receive an electrocardiogram of a subject, a beat analyzer configured to first detect and classify one or more normal beats among a plurality of beats included in the received electrocardiogram, request beat classification for remaining beats except for the one or more normal beats from a remote diagnosis server, and label each of the plurality of beats according to a normal beat detection result and a beat classification result received from the remote diagnosis server, and a rhythm analyzer configured to perform rhythm analysis on the electrocardiogram based on a labeling result.

Abstract: A method for accurately extracting an abnormal potential within a QRS, comprising: in an ideal electrocardiographic signal pre-estimation stage, pre-estimating an ideal electrocardiographic signal using a non-linear transformation technology; according to the pre-estimated ideal electrocardiographic signal, further estimating the ideal electrocardiographic signal by using a spline method, so as to accurately estimate the ideal electrocardiographic signal; and according to the accurately estimated ideal electrocardiographic signal, accurately extracting an abnormal potential within the QRS by means of a mobile standard deviation analysis technology. The method can be used not only on an average electrocardiographic signal after multiple superimposition, but also on a single beat electrocardiographic signal.

Abstract: A heart monitoring system enables a person or user to create and evaluate and ECG without the assistance of a medical professional. A self-adhesive patch with leads is placed over the heart of the person and places the leads in an optimal position to thoroughly monitor the patterns emitted from the heart. The data samples are transmitted to a personal device for display and analysis.

Abstract: A medical device includes at least one electrode to sense an electrocardiogram (ECG) signal of a patient, and a controller coupled to the at least one electrode. The controller is configured to generate a first ECG template based on a first ECG signal of the patient received during a first baselining operation. The controller is configured to determine that the patient has been administered a therapeutic shock, and responsive to the determination that the patient has been administered the therapeutic shock, the controller is configured to initiate a second baselining operation and generate a second ECG template based on a second ECG signal of the patient received during the second baselining operation. The controller is configured to determine whether the patient is experiencing a cardiac event based on a comparison of the second ECG template to a real time ECG signal received during real time monitoring of the patient.

Abstract: Method and system for monitoring an internal electrical impedance of a biological object including Internal Thoracic Impedance (ITI) comprising placing two arrays of electrodes on opposite sides of the biological object, wherein each of said two arrays comprise three equally spaced electrodes; imposing an alternating electrical current between pairs of the electrodes and obtaining voltage signals representative of a voltage drop thereon, calculating two values of internal electrical impedance of the biological object corresponding to the uttermost electrodes of said two arrays of electrodes placed on the opposite sides of the biological object.

Abstract: An intravascular MRI probe assembly for producing real time, three dimension imagery of an interior of a blood vessel includes a probe has diameter is sufficiently small to fit inside of a blood vessel of a human being. An x coil, a y coil and a pair of z coils is each positioned within the probe for producing a magnetic field to facilitate magnetic resonance imaging of an interior of the blood vessel. A first gradient echo coil, a second gradient coil, a shim coil and a magnet is each positioned within the probe. A conductor is coupled to the probe and the conductor extends away from the second end of the probe. Additionally, the conductor is electrically coupled to a magnetic resonance imaging processor to produce a three dimensional image of the interior of the blood vessel.

Abstract: Techniques are described for controlling components of a Magnetic Resonance Imaging (MRI) system with a single controller, such as a Field Programmable Gate Array (FPGA), by dynamically instructing the controller to issue commands to the components using a processor coupled to the controller. According to some aspects, the controller may issue commands to the components of the MRI system whilst actively receiving commands from the processor to be later issued to the components.

Abstract: Magnetic resonance imaging (“MRI”) data are corrected from corruptions due to physiological changes using a self-navigated phase correction technique. Unlike motion correction techniques, the effects of physiological changes (e.g., breathing and respiration) are corrected by making the MRI data self-consistent relative to an absolute uncorrupted phase reference. This phase correction information can be extracted from the acquisition itself, thereby eliminating the need for a separate navigator scan, and establishing an accelerated acquisition. This absolute reference can be computed in a data segmented space, and the subsequent data can be corrected relative to this absolute reference with low-resolution phases.

Abstract: The present disclosure relates to a computed tomography apparatus, comprising: a first semiconductor device with a first radar transceiver IC, a second semiconductor device with a second radar transceiver IC, and at least one third semiconductor device with a third radar transceiver IC, which are arranged at different positions around a tomographical measurement region; a synchronization circuit, which is designed to provide a synchronization signal in order to operate the first, second and third radar transceiver IC as synchronized transmitters and receivers using the synchronization signal; and an evaluation circuit, which is designed to ascertain at least one characteristic of a medium located in the measurement region based on time-of-flight measurements of radar signals received from at least two receivers.

Abstract: The present invention relates to the treatment of cardiac insufficiency. A sensor for measuring the tissue fluid content in the region of the rib cage is implanted in a person suffering from cardiac insufficiency. If the tissue fluid content does not get back to normal within a defined period of time and under treatment with the available standard therapy, treatment with a V1a/V2 vasopessin receptor antagonist is recommended. Dosage of the V1a/V2 vasopressin receptor antagonist and duration of the treatment with the V1a/V2 vasopressin receptor antagonist can be determined on the basis of the acquired sensor data.

Abstract: K-space data obtained from a magnetic resonance imaging scan where motion was detected is split into two parts in accordance with the timing of the motion to produce first and second sets of k-space data corresponding to different poses. Sub-images are reconstructed from the k first and second sets of k-space data, which are used as inputs to a deep neural network which transforms them into a motion-corrected image.

Abstract: A system and method for detecting, timing, and adapting to patient motion during an MR scan includes using the inconsistencies between calculated images from different coil-array elements to detect the presence of patient motion and, together with the k-space scan-order information, determine the timing of the motion during the scan. Once the timing is known, various actions may be taken, including restarting the scan, reacquiring those portions of k-space acquired before the movement, or correcting for the motion using the existing data and reconstructing a motion-corrected image from the data.

Abstract: Systems and methods for integrating and/or registering a shape sensing fiber in or to various instruments are described herein. Registration fixtures and registration techniques for matching the coordinate system of a fiber to the coordinate system of an elongate instrument or other device are provided. Various systems and methods for integrating a shape sensing fiber into an elongate instrument or other device are also described herein.

Abstract: Embodiments of the disclosure can include biomarkers for systems, methods, and devices for detecting and identifying certain substances, such as chemicals, volatile organic compounds (VOCs), volatile gases (VGs), ketones, cannabis, controlled substances, pharmaceuticals, or anesthetics, in the exhaled breath of a subject or person in real-time; and further diagnosing, treating, and addressing one or more associated health conditions or diseases, including a virus, such as COVID-19, tuberculosis (TB), lung cancer, or chronic obstructive lung disease (COPD).

Abstract: An apparatus for assessing the severity of stenosis in a blood vessel includes an elongate body including a distal portion and a centering assembly. The centering assembly is actuatable to selectively center the elongate body in the vessel. A pressure sensor is disposed adjacent the centering assembly and is configured to detect fluid pressure in the vessel. A processing system receives the measured pressure from the pressure sensor, receives data representing the cross-sectional area of the vessel, receives data representing the size of the distal portion, calculates a offset correlation based on the size of the distal portion and based on the size of the vessel, and calculates a fractional flow reserve (FFR) for the vessel as an index of stenosis severity taking into account the offset correlation and the measured fluid pressure from the pressure sensor.

Abstract: Aspects of the subject disclosure may include, for example, obtaining a first plurality of circumference measurements, each of the first plurality of circumference measurements corresponding to a first circumference around a limb of a person at a respective one of a plurality of locations of the limb, each of the first plurality of circumference measurements being obtained from a respective one of a plurality of elastic measurement elements that is positioned at a respective one of the locations; determining, based upon the first plurality of circumference measurements, a first geometric profile along a length of the limb; and outputting data representing the first geometric profile. Other embodiments are disclosed.

Abstract: Disclosed herein are various embodiments of a soft robotic device for assisting hemiparetic patients. In embodiments, the soft robotic device includes an inflatable actuator capable of assisting hemiparetic patients with their gait cycle via application of a force on the gluteus muscle.

Abstract: Embodiments of systems and methods determine one or more gait parameters using acceleration readings generated by an accelerometer coupled to a user. Gait parameters determined by various embodiments may include step length, step width, step time, single limb support time, or double limb support time. The accelerometer may be coupled to one of the user's arms. Exemplary systems may comprise an accelerometer, a processor, and a non-transitory computer readable medium (NTCRM). The processor may process acceleration readings from the accelerometer according to instructions stored on the NTCRM to determine the one or more gait parameters. The processor may communicate the one or more gait parameters to a receiving device. Some embodiments of the system may function as self-contained units and some embodiments may present information corresponding to gait parameters or recommendations regarding gait.