Patents Issued in November 17, 2020
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Patent number: 10836673Abstract: A glass composition formed of a glass frit including P2O5, SiO2, B2O3, Al2O3, ZrO2 and group I-based oxide, wherein P2O5 is contained in an amount of 20 wt % to 40 wt % based on a total weight of the glass frit, SiO2 is contained in an amount of to wt % to 30 wt % based on the total weight of the glass frit, B2O3 is contained in an amount of 3 wt % to 20 wt % based on the total weight of the glass frit, Al2O3 is contained in an amount of 7 to 24 wt % based on the total weight of the glass frit, ZrO2 is contained in an amount of 1 wt % to 7 wt % based on the total weight of the glass frit, and the group I-based oxide is contained in an amount of 7 wt % to 28 wt % based on the total weight of the glass frit.Type: GrantFiled: January 31, 2018Date of Patent: November 17, 2020Assignee: LG ELECTRONICS INC.Inventors: Namjin Kim, Youngseok Kim, Yunsung Kim
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Patent number: 10836674Abstract: A carrier apparatus includes an article including a first major surface, a second major surface, a thickness between the first major surface and the second major surface, and an outer edge extending across the thickness between the first major surface and the second major surface. The carrier apparatus includes a coating including a central portion disposed on the first major surface of the article and an outer exposed portion disposed on the outer edge of the article, and a gasket including a first surface contacting the coating. An outer interface between the first surface of the gasket and the coating defines an outer boundary isolating the central portion of the coating from the outer exposed portion of the coating. Methods of processing a carrier apparatus to remove at least a portion of the coating from the article are also provided.Type: GrantFiled: March 21, 2018Date of Patent: November 17, 2020Assignee: Corning IncorporatedInventors: Michael Patrick Donovan, Jacob Immerman, Jenny Kim, Jae-Chang Lee
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Patent number: 10836675Abstract: A computer or personal communication device or a similar device, comprising a CPU; and a display; wherein the display comprises; an array of optical elements; a touch sensor; and a glass cover having a coating that is oleophobic. The coating of the glass is a polymer having silicon, oxygen and carbon in the backbone. Optionally it may comprise fluorine. The coating has a water contact angle of 65 or more, an oil contact angle of 20 degrees or more, and a pencil hardness of 7H or more. Thus, the coating combines properties of hydro-and oleophobicity and hardness.Type: GrantFiled: March 17, 2016Date of Patent: November 17, 2020Assignee: OPTITUNE OyInventors: Jarkko Leivo, Admir Hadzic, Milja Hannu-Kuure, Ari Karkkainen, Henna Jaervitalo, Rauna-Leena Kuvaja, Matti Pesonen
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Patent number: 10836676Abstract: Disclosed herein are seals for liquid-tight bonding of an optical window comprising a Bi—In alloy. Also disclosed are optical cells comprising the Bi—In alloy seals to provide a liquid-tight seal between a cell housing and a drilled optical window.Type: GrantFiled: August 12, 2019Date of Patent: November 17, 2020Assignee: PIKE Technologies of Wisconsin, Inc.Inventors: Alec Cameron Fisher, Kent Gundlach
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Patent number: 10836677Abstract: A process for the production of a mineral foam includes (i) separately preparing a slurry of cement and an aqueous foam, wherein the cement slurry includes water and Portland cement; (ii) contacting the slurry of cement with the aqueous foam to obtain a slurry of foamed cement; (iii) adding an aluminum salt source before or during step (ii); and (iv) casting the slurry of foamed cement and leave it to set.Type: GrantFiled: December 5, 2016Date of Patent: November 17, 2020Assignee: HOLCIM TECHNOLOGY LTDInventors: Christine Chaumilliat, Christian Blachier, Nicalas Perez, Lilian Ferreint
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Patent number: 10836678Abstract: A lightweight concrete composition includes the concrete components, per yd3 of concrete: Type III Portland cement (lb/yd3) 200-900; metakaolin (lb/yd3) 100-520; calcium sulfoaluminate cement (CSA) (lb/yd3) 40-840; 3/8? lightweight expanded slate aggregate (lb/yd3) 70-550; lightweight fine expanded slate aggregate (lb/yd3) 300-550; expanded glass fine aggregate (0.5-1 mm) 35-90 (lb/yd3); expanded glass fine aggregate (1-2 mm) 35-90 (lb/yd3); water (lb/yd3) 300-350; CSA cement set retarder 0.015 to 0.06 oz per lb of CSA cement; high-range water-reducing admixture 120-1000 (fl. oz/yd3); hydration controlling admixture 0-80 (fl. oz/yd3); reinforcing non-metallic lightweight fibers <1.5? in length 0-8 (lb/yd3); wherein the concrete has a flexural strength of at least 600 psi at 12 hours, a density of 95 to 110 lb/ft3, and a compressive strength at 28 days of at least 7,000 psi. A lightweight concrete wythe and method of making a lightweight concrete wythe are also disclosed.Type: GrantFiled: April 12, 2019Date of Patent: November 17, 2020Assignees: UT-BATTELLE, LLC, UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONInventors: Diana E. Hun, Catherine H. Mattus, Mbakisya Onyango, Joseph Owino, Alex Brent Rollins
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Patent number: 10836679Abstract: The invention relates to building products that contain graphene and/or graphene oxide in the bulk component thereof. The addition of graphene and/or graphene oxide improves the mechanical properties of said building products, particularly in terms of strength.Type: GrantFiled: December 18, 2015Date of Patent: November 17, 2020Assignee: Knauf Gips KGInventors: Marcin Wieteska, Grzegorz Kiedrzyn
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Patent number: 10836680Abstract: A glass ceramic material is disclosed that includes a residual glass, and a crystalline phase that includes a yoshiokaite phase. The yoshiokaite phase constitutes a main crystalline phase of the glass ceramic material. A method for making a glass ceramic material is also disclosed that includes heat treating frit glass to form the glass ceramic material, wherein the frit glass comprises: SiO2 from 15 mol % to 37 mol %; Al2O3 from 40 mol % to 47 mol %; and CaO from 20 mol % to 30 mol %.Type: GrantFiled: August 22, 2018Date of Patent: November 17, 2020Assignee: Corning IncorporatedInventor: Marie Jacqueline Monique Comte
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Patent number: 10836682Abstract: Methods, apparatus and systems using heat exchanger reactors to form polymer derived ceramic materials, including methods for making polysilocarb (SiOC) precursors.Type: GrantFiled: July 22, 2018Date of Patent: November 17, 2020Assignee: Melior Innovations, Inc.Inventors: Richard Landtiser, Wen Liao, Connor Kilgallen, Douglas Dukes, Isabel Burlingham
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Patent number: 10836683Abstract: The invention relates to a method of making a sink comprising: cutting out material that will constitute a bottom of the sink; making a hole for a drain in the bottom of the sink; supporting the edges of the bottom of the sink on a flat support and applying a mechanical force on the rim of the hole for the drain in the bottom of the sink; subjecting the bottom of the sink to a gradual and stepwise heating such that the mechanical force applied deforms said surface; cooling a flat slab; placing additional flat slabs around the first slab, on the sides thereof, to constitute the sides of the sink; externally coating the assembly made with a reinforcement comprising resins, glass fiber, mineral fillers, etc.; and bonding the upper part of the assembly made with the countertop where the sink is located.Type: GrantFiled: June 29, 2018Date of Patent: November 17, 2020Assignee: Manufacturas Siles, S.L.Inventor: Jesus Perez Gomez
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Patent number: 10836684Abstract: A method of fabricating a friction part out of composite material, the method including densifying a carbon yarn fiber preform with a matrix including at least pyrolytic carbon and a ZrOxCy phase, where 1?x?2 and 0?y?1, the matrix being formed by film-boiling or by chemical vapor infiltration from a first precursor for pyrolytic carbon and a second precursor that includes zirconium, the second precursor being a zirconium complex including an alcoxy or carboxylate ligand bonded to zirconium.Type: GrantFiled: October 16, 2018Date of Patent: November 17, 2020Assignee: SAFRAN LANDING SYSTEMSInventors: Patrice Brender, Floriane Demeyer, Sylvain Jacques
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Patent number: 10836685Abstract: A method of providing a plant nutrient composition, the method comprising: (a) contacting a cellulosic material with a composition comprising an amino compound; (b) contacting the cellulosic material with a composition comprising carbon dioxide, sulfur dioxide and mixtures thereof; (c) optionally, contacting the cellulosic material with a composition comprising a source of one or more elements selected from nitrogen, phosphorous, potassium, calcium, magnesium, sulphur, boron, cobalt, chlorine, copper, iron, manganese, molybdenum, zinc and sodium; and (d) optionally, contacting the resultant material with a plant and/or a base growing medium.Type: GrantFiled: January 9, 2018Date of Patent: November 17, 2020Assignee: CCM RESEARCH LIMITEDInventor: Peter Hammond
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Patent number: 10836686Abstract: A water-suspensible, dry, vitamin-hormone horticultural product for promoting plant root growth comprising a combination of one or more plant growth regulators, mycorrhizae, vitamins B1 and B6, sea kelp and beneficial microbes in a carrier. In one embodiment the product is a dry powder of about 2.00 wt % indole-3-butyric acid in crystalline solid form; about 0.20 wt % thiamine mononitrate (B1) in water-soluble powder form; about 0.20 wt % pyridoxine HCl (B6) in water-soluble powder form; about 2.64 wt % Mycorrhizae in water-soluble powder form; about 1.06 wt % sea kelp extract in brown flake form; about 0.88 wt % Bacillus amyloliquefaciens in water-soluble powder form; about 0.07 wt % sodium lauryl sulfoacetate in water-soluble powder form; and about 92.35 wt % maltodextrin in water-soluble powder form.Type: GrantFiled: June 26, 2020Date of Patent: November 17, 2020Assignee: Mitogrow, LLCInventor: John Christopher Ball
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Patent number: 10836687Abstract: A method of producing DEMN eutectic comprises reacting a reactant mixture comprising ethylenediamine and diethylenetriamine with aqueous nitric acid to form a reaction mixture comprising diethylentriamine trinitrate and ethylenediamine dinitrate. The reaction mixture is combined with methylnitroguanidine and nitroguanidine to form an aqueous slurry. Water is removed from the aqueous slurry. A method of producing an energetic composition, and a system for producing DEMN eutectic are also described.Type: GrantFiled: May 1, 2017Date of Patent: November 17, 2020Assignee: Northrop Grumman Innovation Systems, Inc.Inventors: Stephen P. Velarde, Harold E Johnston
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Patent number: 10836688Abstract: The present invention relates to a method of carrying out an organic reaction in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose.Type: GrantFiled: January 14, 2020Date of Patent: November 17, 2020Assignees: ABBVIE INC., ABBVIE DEUTSCHLAND GMBH & CO. KGInventors: Wilfried Braje, Katarina Britze, Justin D. Dietrich, Anais Jolit, Johannes Kaschel, Johanna Klee, Tanja Lindner
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Patent number: 10836689Abstract: The present disclosure provides systems and methods for producing olefins via an oxidative coupling of methane (OCM) process. The systems and methods may comprise the use of a staged process comprising at least one non-adiabatic section that is in thermal communication with a heat transfer medium and at least one substantially adiabatic section. The systems and methods may also comprise the use of a diluent stream which may improve methane conversion in an OCM reactor and an ethylene/ethane ratio in a post-bed cracking unit. The methods and systems may further comprise injecting oxygen (O2) and a paraffin into a gas stream containing a radical transfer agent to provide a reaction mixture. The reaction mixture may be held in a vessel for a time period greater than an auto-ignition delay time (AIDT), such that the reaction mixture may ignite to liberate heat and convert to a product mixture comprising olefins.Type: GrantFiled: July 9, 2018Date of Patent: November 17, 2020Assignee: Lummus Technology LLCInventors: Joel Cizeron, David Sheridan, Gregory J. Turk, Satish Lakhapatri, Rong Fan, Guido Radaelli, Franciscus J. A. Martens, Jarod McCormick, David C. Grauer, Fabio R. Zurcher, Daniel Rosenberg
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Patent number: 10836690Abstract: A dehydrogenation system includes a plurality of dehydrogenation reactors valved to operate in alternating dehydrogenation modes and regeneration modes in a timed sequence in a system cycle by way of the plurality of valves; a digital programmable controller connected to the plurality of valves for sequencing the reactors; and means for determining the productivity characteristics of each reactor over a system cycle. The digital controller is operable to re-sequence the reactors to reduce either peak productivity or productivity deltas over an initial system cycle. After resequencing, production may be increased with the more uniform productivity profile of the re-sequenced system without exceeding system limits, such as compressor operating limits.Type: GrantFiled: September 30, 2019Date of Patent: November 17, 2020Assignee: TPC Group LLCInventors: Joseph G. Duff, David S. Hager, Gilbert D. Valdez, Joseph A. Comeaux, Michael O. Nutt
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Patent number: 10836691Abstract: A process is provided including subjecting a raw C5 stream containing C5 diolefins to extractive distillation to form C5 diolefins and a raffinate stream. The process includes subjecting the raffinate stream to dehydrogenation to form additional C5 diolefins, which are recycled to the extractive distillation. Another process includes modifying a C5 diolefin extractive distillation unit by forming a recycle loop with a C5 olefin dehydrogenation reactor. A system is provided that includes a C5 diolefin extractive distillation unit and a C5 olefin dehydrogenation reactor that are arranged in a recycle loop. A process is provided that includes subjecting a raffinate stream containing C5 olefins from an extractive distillation unit to dehydrogenation to form C5 diolefins.Type: GrantFiled: September 22, 2015Date of Patent: November 17, 2020Assignee: FINA TECHNOLOGY, INC.Inventors: James Assef, Scott Cooper, Kaushik Gandhi
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Patent number: 10836692Abstract: The present invention provides a method for separating HFC-245cb and (E)-HFO-1234ze having close boiling points, i.e., boiling points with only 1° C. difference, by extractive distillation from a composition containing the HFC-245cb and the (E)-HFO-1234ze. More specifically, the present invention is a method for separating HFC-245cb and (E)-HFO-1234ze from a composition containing the HFC-245cb and the (E)-HFO-1234ze, the method comprising subjecting the composition to extractive distillation using at least one extractant selected from the group consisting of halogenated hydrocarbons, halogenated unsaturated hydrocarbons, nitriles, ketones, carbonates, alcohols, hydrocarbons, esters and ethers.Type: GrantFiled: November 12, 2015Date of Patent: November 17, 2020Assignee: DAIKIN INDUSTRIES, LTD.Inventors: Mana Shimokawa, Tatsuya Takakuwa, Kazuhiro Takahashi
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Patent number: 10836693Abstract: The present invention provides a process for the preparation of Docosanol (I). The process comprises reducing cis-13-Docosenoic acid (V) to obtain Docosanoic acid (III), which is further reduced to obtain Docosanol (I).Type: GrantFiled: May 28, 2018Date of Patent: November 17, 2020Assignee: Aurobindo Pharma Ltd.Inventors: Nandi Sukumar, Theriviam Sudalayandi Shanmugam Sundaram Dhanraj, Sreedhar Reddy Dwarakapally, Ravi Kumar Gupta Miriyala, Sivakumaran Meenakshisunderam
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Patent number: 10836694Abstract: The present invention aims to improve the production capacity of alcohol in a method of producing high concentration alcohol using a distillation column and an adsorption-desorption column. The method is a method of producing high concentration alcohol by dehydration of a water-alcohol mixture, including: a distillation step of introducing a water-alcohol mixture into a distillation column to obtain crude alcohol; and an adsorption-desorption step of introducing a part of the crude alcohol into an adsorption-desorption column to obtain high concentration alcohol; wherein a further part of the crude alcohol is introduced into a dehydration apparatus to obtain high concentration alcohol.Type: GrantFiled: July 29, 2019Date of Patent: November 17, 2020Assignee: Mitsubishi Chemical CorporationInventors: Tadafumi Yamamura, Hideto Hidaka, Hiroyuki Kakiuchi
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Patent number: 10836695Abstract: The present invention relates to a process for treating a glycerol solution comprising fatty acid soaps obtained in a biodiesel production process, to obtain a glycerol enriched phase.Type: GrantFiled: April 7, 2017Date of Patent: November 17, 2020Assignee: A & C FREEMANInventor: Andrew Freeman
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Patent number: 10836696Abstract: The present invention provides a method for increasing the UV transmittance of ethylene glycol. The method uses an ethylene glycol solution and hydrogen as raw materials, and uses an alloy catalyst comprising nickel, one or more rare-earth elements, tin, and aluminum, the contents thereof in parts by weight being 10-90, 1-5, 1-60, and 5-9, respectively. The method of the present invention uses an inexpensive, stable-in-aqueous-phase, carrier-free alloy as a catalyst, and continuously adds hydrogen to reduce unsaturated impurities in ethylene glycol. In application of the method of the present invention in continuous industrial-scale production, the use of this type of alloy catalyst could be especially significant for the achievement of long-term system stability and control of production costs.Type: GrantFiled: March 30, 2017Date of Patent: November 17, 2020Assignees: The Coca-Cola Company, Changchun Meihe Science and Technology Development Co., Ltd.Inventors: Yi Yuan, Haiyu Ren
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Patent number: 10836697Abstract: Processes to prepare lightly branched surfactant products comprise combining at least one olefin and a coordination-insertion catalyst under conditions such that at least one oligomer product is formed. The surfactant products comprise a main carbon chain containing an average of between 0.5 and 2.5 branches, wherein more than 50% of the branches are ethyl branches, wherein the branches are located more than one carbon away from each end of the main carbon chain in more than 20% of surfactant product molecules.Type: GrantFiled: December 13, 2018Date of Patent: November 17, 2020Assignee: Dow Global Technologies LLCInventors: Paul R. Elowe, Wanglin Yu, Brad C. Bailey, Michael L. Tulchinsky, Andre B. Argenton, Daniel J. Arriola, Jerzy J. Klosin
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Patent number: 10836698Abstract: Provided is a process for preparing dry methacrolein which maximizes capture of methanol. Also provided is a process for producing methyl methacrylate.Type: GrantFiled: May 24, 2018Date of Patent: November 17, 2020Assignee: Rohm and Haas CompanyInventors: Reetam Chakrabarti, Charles Como, Sarah L. Hruby, Dmitry A. Krapchetov, Minh N. Ngo, Muhunthan Sathiosatham, Mark A. Silvano
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Patent number: 10836699Abstract: Provided is a process for preparing methacrolein which maximizes capture of methanol. Also provided are processes for producing methacrylic acid and methyl methacrylate.Type: GrantFiled: May 24, 2018Date of Patent: November 17, 2020Assignee: Rohm and Haas CompanyInventors: Reetam Chakrabarti, Dmitry A. Krapchetov, Mark A. Silvano, Jinsuo Xu
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Patent number: 10836700Abstract: A process for preparing a ketone or carboxylic acid by catalytic oxidation of a secondary or primary alcohol comprises adding the secondary or primary alcohol as a raw material and N-hydroxyphthalimide (NHPI) combined with phthalocyanine, serving as a catalytic system, into an amount of an organic solvent into which oxygen gas is then introduced, to proceed with an oxidation reaction to give the ketone or carboxylic acid. The oxygen gas is employed as the source of an oxidant. The oxidation reaction may be carried out under normal pressure at 60 to 120° C. for 9 to 36 hours. The process can produce a high yield of ketone or carboxylic acid. Compared with conventional technology, the process has several advantages, such as the green oxidant, the cheap catalyst which can also be easily prepared and separated, and mild reaction conditions, and it is also an environmentally friendly process for alcohol oxidation.Type: GrantFiled: April 16, 2020Date of Patent: November 17, 2020Assignee: Shanghai Institute of TechnologyInventors: Xiaoling Sun, Fei Li, Lingjun Ye, Zhilin Tang, Jinxin Zhao, Hehua Li
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Patent number: 10836701Abstract: The present disclosure describes that high purity cholesterol is obtained by the processes of the invention without any further purification step, such as a crystallizing step from a solvent, but rather by distilling steps alone. The disclosures provides a process that includes the production of compositions having a cholesterol content over 75% in weight, from fish oil processing waste residues.Type: GrantFiled: March 26, 2020Date of Patent: November 17, 2020Inventors: Alejandro Markovits Rojas, Steven Lee Härting Eckman, Thomas Francis Härting Glade
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Patent number: 10836702Abstract: The present technology relates to synthesis of resveratrol compositions, in particular to methods of synthesizing resveratrol salicylates such as those formed through the activation of resveratrol and salicylic acid, and cosmetic and pharmaceutical compositions comprising the same.Type: GrantFiled: May 16, 2019Date of Patent: November 17, 2020Assignee: Biocogent, LLCInventors: Joseph D. Ceccoli, Michael L. Ingrassia, Christopher M. Judd, Brian R. Costello
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Patent number: 10836703Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.Type: GrantFiled: August 18, 2020Date of Patent: November 17, 2020Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGYInventors: Yongbo Wang, Yuanyuan He, Gennian Mao, Mudan Xu, Xingke Ju, Han Li, Qianqian Zhao, Bin Tian, Chengyuan Liang
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Patent number: 10836704Abstract: Preparing ethanolamines/ethyleneamines in the presence of an amination catalyst prepared by reducing a calcined catalyst precursor containing one or more metals of groups 8, 9, 10 and/or 11 and low basicity achieved by: a) coprecipitating catalyst precursor and active composition additionally contains alkali metals or alkaline earth metals; b) the catalyst precursor is prepared by impregnating a support material or precipitative application onto a support material containing alkali metals, Be, Ca, Ba, Sr, hydrotalcite, chrysotile or sepiolite; c) the catalyst precursor is prepared by impregnating a support material or precipitative application onto a support material and the active composition of the catalyst support contains one or more of alkali metals and alkaline earth metals; d) the catalyst precursor is calcined at temperatures of 600° C. or more; or e) the catalyst precursor is prepared by a combination of a) and d), b) and d), or c) and d).Type: GrantFiled: December 7, 2017Date of Patent: November 17, 2020Assignee: BASF SEInventors: Marie Katrin Schroeter, Alvaro Gordillo, Andrei-Nicolae Parvulescu, Johann-Peter Melder, Carlos Lizandara Pueyo, Juergen Bechtel, Thomas Heidemann, Stephan A. Schunk, Ulrich Mueller
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Patent number: 10836705Abstract: A method of producing pharmaceutical grade bretylium tosylate comprising low amounts of mutagenic impurities. The method comprises forming bretylium tosylate having a purity of less than 99.5% and purifying the bretylium tosylate by: i) forming a slurry of the bretylium tosylate with a mixture of acetone and ethyl acetate; ii) filtering the slurry to obtain purified bretylium tosylate. The bretylium tosylate so produced has a purity of at least 99.5%, and suitably comprises less than 0.5 ppm of the potentially mutagenic impurity ethyl p-toluenesulfonate. The bretylium tosylate so produced also suitably comprises less than 0.5 ppm of the potentially mutagenic impurity 2-bromobenzylbromide.Type: GrantFiled: August 14, 2019Date of Patent: November 17, 2020Assignee: TOPCHEM PHARMACEUTICALS LIMITEDInventor: Donal Coveney
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Patent number: 10836706Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.Type: GrantFiled: February 23, 2017Date of Patent: November 17, 2020Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit Parhi, Gifty A. Blankson, Liping Wang, Xiao Chen, Yongzheng Zhang, Malvika Kaul, Daniel S. Pilch
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Patent number: 10836707Abstract: Disclosed are a mild and efficient preparation method for an ?-acyloxyenamide compound and a use thereof in the synthesis of an amide and a polypeptide. The ?-acyloxyenamide compound is obtained by an addition reaction of a ynamide and a carboxylic acid in dichloromethane under conditions where the temperature is 0° C. to 50° C.; the produced ?-acyloxyenamide compound can react with an amine compound to produce an amide or a polypeptide; the two reactions can be carried out step by step, and can also be carried out in one pot. According to the invention, the reaction conditions are mild and no metal catalyst is required; when the carboxylic acid, which has chirality on an alpha site of carboxyl, forms an amide bond or a peptide bond, no racemization occurs; and the operation is simple and the application range is wide.Type: GrantFiled: January 20, 2017Date of Patent: November 17, 2020Inventors: Junfeng Zhao, Long Hu, Silin Xu, Zhenguang Zhao
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Patent number: 10836708Abstract: Provided herein are processes, compounds and compositions for making (S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid. Also provided herein a pharmaceutical compositions containing (S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid.Type: GrantFiled: May 28, 2019Date of Patent: November 17, 2020Assignee: NORTHWESTERN UNIVERSITYInventors: Richard B. Silverman, Matthew Moschitto
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Patent number: 10836709Abstract: A process for the preparation of a solid composition of an amino acid diacetic acid compound wherein the amino acid diacetic acid compound is methyl glycine-N,N-diacetic acid or a salt thereof, or glutamic N,N-diacetic acid or a derivative thereof, as well as the product obtained by such process are disclosed. The process includes feeding a saturated or oversaturated aqueous composition of the amino acid diacetic acid compound in an aqueous solvent to a drum dryer, wherein the aqueous composition is fed to the drum surface with a layer thickness of from about 0.1 to about 10 mm, the drum has a surface temperature of from about 80 to about 180° C., and the drum operates at a tangential speed of from about 0.1 to about 100 m/min. The method further includes removing the mass from the drum before a full revolution of the drum.Type: GrantFiled: July 3, 2018Date of Patent: November 17, 2020Assignee: NOURYON CHEMICALS INTERNATIONAL B.V.Inventors: Paulus Johannes Cornelis Van Haeren, Roy Doppen, Elwin Schomaker, Raymond Jean Cécile Vaessen, Marco Ypma, Stijn Oudenhoven, Martin Heus
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Patent number: 10836710Abstract: The present invention generally relates to a process using a mechanochemical approach exploiting the mechanical milling of reactants for the manufacturing of acetyl Iopamidol and, more generally, of key intermediates of radiographic contrast agents, and of the contrast agents themselves.Type: GrantFiled: December 4, 2017Date of Patent: November 17, 2020Assignee: BRACCO IMAGING SPAInventors: Alessandro Barge, Francesca Baricco, Giancarlo Cravotto, Roberta Fretta, Luciano Lattuada
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Patent number: 10836711Abstract: The present invention concerns a process for the preparation of organo-iodized compounds, as well as their preparation intermediates. More particularly, the present invention concerns a process for the preparation of organo-iodized compounds which can be used as preparation intermediates in the synthesis of iodized contrast agents.Type: GrantFiled: February 9, 2018Date of Patent: November 17, 2020Assignee: GUERBETInventors: Myriam Petta, Stephan Pellinghelli
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Patent number: 10836712Abstract: A flavour composition comprising a compound according to the formula (I) or edible salts thereof, wherein R1 is an alkyl residue containing 6 to 20 carbon atoms, or an alkene residue containing from 9 to 25 carbon atoms with 1 to 6 double bonds, R1 together with the carbonyl group to which it is attached is a residue of a carboxylic acid, and NR2R3, in which R3 is H or together with R2 and the N-atom to which they are attached, a 5-membered ring, is a residue of an amino acid, in particular a proteinogenic amino acid, ornithine, gamma-aminobutyric acid or beta alanine, or a 1-amino cycloalkyl carboxylic acid.Type: GrantFiled: March 28, 2013Date of Patent: November 17, 2020Assignee: Givaudan S.A.Inventors: Feng Shi, Harry Renes, Esther Van Ommeren, Susanna Magdalena Vorster, Yili Wang, Adri De Klerk, Xiaogen Yang
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Patent number: 10836713Abstract: The invention relates to a method for producing isocyanates by phosgenating the corresponding primary amines in the gas phase, wherein the raw gaseous reaction product mixture is cooled and partially condensed by being brought into contact with at least one flow of a quenching liquid, and using a part of the condensed reaction product mixture as a component, optionally the only component, of the at least one flow of the quenching liquid after an additional cooling process. The quenching liquid used in total comprises, based on the total mass, organic solvents in a proportion of maximally 25% by mass, and the remainder of up to 100% by mass consists of at least the isocyanate to be produced. Furthermore, the reaction product mixture components which are not condensed under the influence of the quenching liquid are freed of isocyanate components in a scrubber column, and a scrubber liquid- and isocyanate-containing liquid flow is obtained with, based on the total mass, a content of organic solvents of 0.Type: GrantFiled: June 6, 2018Date of Patent: November 17, 2020Assignee: Covestro Deutschland AGInventors: Joachim Zechlin, Thomas Stetten
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Patent number: 10836714Abstract: Ketamine derivatives and pharmaceutical compositions thereof are disclosed. When administered orally the ketamine derivatives provide increased bioavailability of ketamine in the systemic circulation. The ketamine derivatives can be used to treat neurological diseases, psychological diseases and pain.Type: GrantFiled: April 2, 2020Date of Patent: November 17, 2020Assignee: XW LABORATORIES INC.Inventors: Jia-Ning Xiang, Xuesong Xu, Hao-Wei Shih, Wai-Si Eng
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Patent number: 10836715Abstract: A process for preparing polyaryl ethers in which a polycondensation of the monomer building blocks is carried out using microwave irradiation leads to thermoplastic molding compositions having improved color properties.Type: GrantFiled: July 6, 2017Date of Patent: November 17, 2020Assignee: BASF SEInventors: Frauke Thrun, Joaquim Henrique Teles, Jun Gao
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Patent number: 10836716Abstract: An exemplary process for the production of alkali metal salts of dialkyldithiocarbamic acids produced according to the following steps: i) reaction of one or more dialkylamines, carbon disulphide and alkali metal hydroxides to form alkali metal salts of dialkyldithiocarbamic acids; ii) crystallisation to form a crystal suspension of alkali metal salts of dialkyldithiocarbamic acids; iii) separation of crystals of alkali metal salts of dialkyldithiocarbamic acids from the mother liquor in step ii; (iv) recirculation of the separated mother liquor into the crystallisation process; and v) drying of the alkali metal salts of dialkyldithiocarbamic acids.Type: GrantFiled: April 10, 2018Date of Patent: November 17, 2020Assignee: EPC ENGINEERING & TECHNOLOGIES GMBHInventors: Jens Henkel, Jurgen Rassbach, Tobias Przynosz
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Patent number: 10836717Abstract: Disclosed herein are compounds of formula Ar—N(SO2F)2, wherein Ar is selected from an optionally substituted aryl, an optionally substituted five-membered heteroaryl, or an optionally substituted six-membered heteroaryl. Also disclosed are methods of synthesizing the above compounds by reacting a compound of formula Ar—NH—R9 with MN(SO2F)2.Type: GrantFiled: August 14, 2018Date of Patent: November 17, 2020Assignees: BioDuro, LLC, Pfizer Inc.Inventors: Hua Zhou, Paramita Mukherjee, Rongqiang Liu, Christopher W. Am Ende, Tianjing Deng
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Patent number: 10836718Abstract: The invention describes a process for making astacene of formula 1, the exocyclic double bonds thereof having either an E configuration or an E- and/or Z-configuration, wherein astaxanthin of the general formula 2 having asymmetric centers 3 and 3?, each of which respectively having an (S)- or (R)-conformation and the exocyclic double bonds of said astaxanthin 2 having either an E- or E- and/or Z configuration, is oxidized in the presence of at least one tertiary alcoholate.Type: GrantFiled: November 20, 2017Date of Patent: November 17, 2020Assignee: BASF SEInventors: Bernd Schaefer, Wolfgang Siegel
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Patent number: 10836719Abstract: An object is to provide a method for easily producing maleimide (MI) in which trace amounts of residual acid components as impurities in a crude MI are efficiently reduced, that is, the acid value is sufficiently reduced. <1> A method for producing purified MI, comprising reducing an acid value of crude MI by 50% or more, by adding carbodiimide (CDI) to a solution comprising the crude MI to react an acid component in the crude MI with the CDI. <2> The method for producing purified MI, comprising adding 0.5% by mass or more and 8% by mass or less of the CDI with respect to a mass of the crude MI for reaction. <3> The method for producing purified MI, wherein the CDI is N,N?-diisopropyl carbodiimide (DIC). <4> The method for producing purified MI, comprising removing a urea derivative of the CDI (CDI-U) by-produced when reacting the acid component in the crude MI with the CDI.Type: GrantFiled: April 30, 2019Date of Patent: November 17, 2020Assignee: UNITIKA LTD.Inventors: Yuki Yamada, Tatsuya Morikita, Yosuke Sugimoto, Takeshi Yoshida, Akira Shigeta, Yoshiaki Echigo
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Patent number: 10836720Abstract: Disclosed herein, inter alia, are inhibitors of integrin alpha 5 beta 1 and methods of using the same.Type: GrantFiled: March 31, 2017Date of Patent: November 17, 2020Assignee: The Regents of the University of CaliforniaInventors: Dean Sheppard, Aparna Sundaram, William F. Degrado, Hyunil Jo, Joel McIntosh
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Patent number: 10836721Abstract: Thalidomide analogs and methods of using the thalidomide analogs are disclosed. Some embodiments of the disclosed compounds exhibit anti-angiogenic and/or anti-inflammatory activity. Certain embodiments of the disclosed compounds are non-teratogenic.Type: GrantFiled: June 24, 2020Date of Patent: November 17, 2020Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, University Court of the University of AberdeenInventors: Nigel H. Greig, Weiming Luo, David Tweedie, Neil Vargesson, Shaunna Beedie, William Douglas Figg
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Patent number: 10836722Abstract: The disclosure relates to a compound having Formula (I?): and in particular, Compound I-126: which modulates the activity of EGFR, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which EGFR plays a role.Type: GrantFiled: June 13, 2019Date of Patent: November 17, 2020Assignee: DANA-FARBER CANCER INSTITUTE, INC.Inventors: Nathanael S. Gray, Michael Eck, Pasi Janne, Hwan Geun Choi, Jaebong Jang, Kwok-Kin Wong
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Patent number: 10836723Abstract: There is a demand for the development of a technique according to which sodium 2,2,6,6-tetramethylpiperidides (Na-TMPs) can be economically and efficiently synthesized through simple operations including a small number of steps under mild conditions in a short period of time. Also, there is a demand for the development of a technique according to which high-quality Na-TMPs that do not contain lithium or lithium compounds such as Li-TMP can be synthesized. The method for synthesizing sodium 2,2,6,6-tetramethylpiperidides includes a step of obtaining sodium 2,2,6,6-tetramethylpiperidides by reacting, in a reaction solvent, 2,2,6,6-tetramethylpiperidines with a dispersion product obtained by dispersing sodium in a dispersion solvent or an organosodium compound having an aromatic ring obtained through a reaction with a dispersion product obtained by dispersing sodium in a dispersion solvent.Type: GrantFiled: January 24, 2018Date of Patent: November 17, 2020Assignee: KOBELCO ECO-SOLUTIONS CO., LTD.Inventors: Yoshiaki Murakami, Miyuki Fukushima, Kazuhiko Takai, Sobi Asako