Abstract: The invention related to a method for manufacturing a distractor for skeletal attachment to a jaw of a patient. This method comprises the steps of: (a) generating a three-dimensional image of the jaw of the patient or of parts of the jaw; (b) generating a virtual model of a patient-specific distractor using the three-dimensional image; and (c) manufacturing the distractor or parts thereof with the help of the virtual model.

Abstract: A joint alignment method comprises using imaging data of at least a portion of a leg to create a leg model, wherein the leg model includes a femur having medial and lateral condyles and a tibia having tibial plateaus that are configured to engage the medial and lateral condyles at a knee joint, displaying an image of the leg model for manipulation by a user, locating a pivot point within one of the medial or lateral condyles, and rotating, in the displayed image, the tibia with respect to the femur, about the pivot point, to obtain a desired knee joint articulation in a specified plane.

Abstract: Methods and system perform tool tracking during minimally invasive robotic surgery. Tool states are determined using triangulation techniques or a Bayesian filter from either or both non-endoscopically derived and endoscopically derived tool state information, or from either or both non-visually derived and visually derived tool state information. The non-endoscopically derived tool state information is derived from sensor data provided either by sensors associated with a mechanism for manipulating the tool, or sensors capable of detecting identifiable signals emanating or reflecting from the tool and indicative of its position, or external cameras viewing an end of the tool extending out of the body. The endoscopically derived tool state information is derived from image data provided by an endoscope inserted in the body so as to view the tool.

Abstract: Systems, devices, and methods for electroporation ablation therapy are disclosed. An apparatus may be configured to activate a field generator to generate an electric or magnetic field such that signals are received by a receiver coupled to an ablation device disposed adjacent to a tissue surface. Processed data associated with the signals may be obtained. A position and an orientation of the ablation device may be determined based on the processed data. An expected ablation zone of the ablation device in the tissue surface may be determined based on the position and the orientation of the ablation device. A map of the tissue surface and a visual representation of the expected ablation zone disposed in the map of the tissue surface may be displayed.

Abstract: A method and system assist a physician in performing an ophthalmic surgery. The method includes receiving a quasi-real time image of at least a first portion of the eye. The at least the first portion of the eye includes an operating field for the ophthalmic surgery. A recommended next region and a recommended next procedure are determined based on the quasi-real time image and a computational model of the eye. An expected next result for the recommended next procedure is calculated using the quasi-real time image and the computational model. The recommended next region, the recommended next procedure and the expected result are provided to the physician.

Abstract: A robotic patient protection system and method including a head mask structure, configured to protect the head of a patient, for use in robotic surgical procedures.

Abstract: A medical robotic system comprises a memory for receiving intraoperative external image data for at least a portion of a patient anatomy. The portion of the patient anatomy includes a target anatomy, and the intraoperative external image data includes image data for the target anatomy and for an effect of a substance on the target anatomy. The system further includes a processor configured for at least semi-automatically controlling a medical instrument of the medical robotic system based on the intraoperative external image data to deliver the substance to the target anatomy through the medical instrument. The processor is further configured for determining the effect of the substance on the target anatomy. The processor is further configured for, using the determined effect, adjusting a control parameter for delivering the substance to the target anatomy.

Abstract: A system for use in surgery includes a central body, a visualization system operably connected to the central body, a video rendering system, a head-mounted display for displaying images from the video rendering system, a sensor system, and a robotic device operably connected to the central body. The visualization system includes at least one camera and a pan system and/or a tilt system. The sensor system tracks the position and/or orientation in space of the head-mounted display relative to a reference point. The pan system and/or the tilt system are configured to adjust the field of view of the camera in response to information from the sensor system about changes in at least one of position and orientation in space of the head-mounted display relative to the reference point.

Abstract: Systems and methods for embodiments of a hyperdexterous robotic system using groundless user input devices (UIDs). In some embodiments, the hyperdexterous system allows for the slave control to follow the master control even when the two are misaligned. The motion of the master control occurring in multiple degrees of freedom may be decoupled into its component parts and processed differently. Each degree of freedom may be processed independently and scaled differently. For example, in some embodiments, only the roll motion of the groundless user interface device is transferred, in some embodiments, the master slave control is only allowed when the master and slave are within a certain region of each other.

Abstract: A robot system includes a robot including a tactile sensor and a hand having the tactile sensor, a tactile information generator configured to generate tactile information defined by a pressure distribution based on pressures detected by a plurality of pressure sensors and spatial positions of the plurality of pressure sensors, and output the tactile information, a manipulator configured to make an operator sense the pressure distribution according to the tactile information outputted from the tactile information generator, and when the operator manipulates the manipulator, output manipulating information according to the manipulation, and a robot controller configured to control operation of the hand of the robot according to the manipulating information outputted from the manipulator.

Abstract: A method may include coupling a proximal end of a first cannula to a first manipulator of a surgical system, the first manipulator being configured to remotely actuate movement of the first cannula, wherein the first cannula comprises a rigid portion disposed between the proximal end and a distal end of the first cannula, the rigid portion having a curved longitudinal axis, and coupling a proximal end of a second cannula to a second manipulator of a surgical system, the second manipulator being configured to remotely actuate movement of the second cannula, wherein the second cannula comprises a rigid portion disposed between the proximal end and a distal end of the second cannula, the rigid portion having a curved longitudinal axis.

Abstract: A surgical instrument including a shaft including a distal portion and an articulatable portion is disclosed. The articulatable portion, positioned proximal to the distal portion, includes a plurality of joint members. A first articulation cable extends through each first channel of each of the plurality of joint members and a second articulation cable extends through each second channel of each of the plurality of joint members to the distal portion. The first and second articulation cables are transitionable between: (i) an unlocked state, where the first and second articulation cables are free to translate distally and proximally and the plurality of joint members are slidable relative to one another to pivot the distal portion away from a longitudinal axis, and (ii) a locked state, where translation of the first and second articulation cables is locked, causing a position of the distal portion relative to the longitudinal axis to be locked.

Abstract: Systems and methods for controlling an elongate device include a console. The console includes a first recess and a removable first input control for controlling motion of the medical device. The console also may include one or more first sensors located about the first recess that detect motion of the first input control and detect operator contact with the first input control. The console also may include an integrated display screen arranged to display status information for the medical device. In some embodiments, the first input control controls an insertion depth or steering of the medical device, and may be in the form of a scroll wheel forming a part of a removable control assembly.

Abstract: The invention relates to a sterile surgical drape comprising a cover portion for a tracking reference array, wherein at least a part of the cover portion is formed inherently stable and has a form adapted to accommodate multiple tracking markers of a tracking reference array for computer-assisted surgery. Further, it relates to a surgical draping system and a medical navigation method using such a drape.

Abstract: A medical kit 100 includes a drape 1323. A plurality of pockets (1302,1303,1304,1305, 1306,1307) are disposed along a bottom edge of the drape 1323 in a linear, side-by-side arrangement. A plurality of medical implements (1310,1311,1312,1313,1314,1315) are stowed in the plurality of pockets on a one-to-one basis. Medical indicia (1316,1317,1318,1319,1320,1321) is disposed along each pocket. The medical indicia can include comprising one or more educational prompts that instruct medical personnel how to use a particular medical implement disposed in a pocket to complete a central catheter dressing change.

Abstract: A component (14) for a medical instrument includes a shaft (15), a transmission device (16), which is movable in the shaft (15), for transmitting a force from a manipulation device (18) coupled to the proximal end of the component (14) to a tool (13) at the distal end of the component (14), an abutment surface (86) on the shaft (15), and an abutment surface (36) on the transmission device (16). The abutment surface (86) of the shaft (15) and the abutment surface (36) of the transmission device (16) are arranged such that a mechanical contact between the abutment surface (36) of the transmission device (16) and the abutment surface (86) of the shaft (15) limits a movement of the transmission device (16) relative to the shaft (15) in the proximal direction.

Abstract: A model of a body part, e.g., liver, of which the internal structure can be observed easily; and others. In a liver model according to the present invention, the liver parenchyma is formed in the form of a frame to make it possible to observe the portal, veins, a tumor and others in the inside of the frame 31a easily. In addition, the liver model can be handled easily by gripping a gripping part provided at the lower end surface of the inferior vena cava, and the tumor is integrated with the liver model by means of a joint part. The liver model can be manufactured from a model material using a 3D printer on the basis of three-dimensional shape data for model manufacturing purposes, which are produced using an information processing device.

Abstract: A method for minimally invasive surgery using therapeutic ultrasound in spine and orthopedic orthopedic procedures. The method includes a minimally invasive access port, a therapeutic ultrasound probe to treat a targeted area through the port, and a protective sheath that enables application of the therapeutic ultrasound without causing unintended tissue damage.

Abstract: The invention comprises a surgical instrument assembly for minimally invasive surgery. The surgical instrument assembly comprises a light emitting arrangement and a surgical instrument. The surgical instrument has a distal end and a proximal end and comprises a handle portion at its proximal end and a grasper at its distal end, the grasper comprising at least two jaws and having a closed grasper position and an open position where a grasping space is formed between the jaws. The light emitting arrangement comprises a light source for generating light and a projector for projecting at least a beam of light comprising a string shape perpendicular to the optical axis of the beam of light. At least the projector of the light emitting arrangement is at least temporally fixed to the surgical instrument proximally to the jaws and is arranged to project the string shaped beam of light such that it will be broken upon a lateral movement of an object into the grasping space.

Abstract: A method for displaying an anatomical image of a coronary artery on a graphical user interface with information acquired from a plurality of intravascular image frames. The method may include detecting qualitative information from the plurality of intravascular image frames, creating one or more indicator(s) from the qualitative information detected, and determining a spatial relationship between the anatomical image and a plurality of acquisition locations of the plurality of intravascular image frames and generating its linear representation. The method also includes displaying the anatomical image of the coronary artery with the linear representation overlaid thereon on a display device and overlaying the one or more indicator(s) representing at least one type of qualitative information on the anatomical image along the linear representation.

Abstract: Medical observation apparatus (1) and method for observing an object or patient (67) in an operation area (21). Solutions of the art (3, 5) do not allow displaying further information, are expensive, bulky and non-intuitive.

Abstract: A biopsy marker having a spring-loaded anchor. The biopsy marker includes an insertion orientation and an anchored orientation. In the insertion orientation, the biopsy marker is manipulated under force to reduce the lateral span/cross-sectional area of the marker. In the anchored orientation, the biopsy marker is released and free to actively spring into a configuration in which the lateral span/cross-sectional area is greater than the lateral span/cross-sectional area of the biopsy marker when in the insertion orientation. In an embodiment, the spring-loaded anchor is configured to spring about a predefined rotational axis. An embodiment of the biopsy marker may be comprised of a single wire construction.

Abstract: An imaging device including a support, a mouth retractor fastened to the support and defining a retractor opening, a colorimetric calibration chart and/or a translucence calibration chart and a light source that is oriented so as to illuminate both the teeth of the patient through the retractor opening and the colorimetric calibration chart and/or the translucence calibration chart. Structure for fastening an image acquisition apparatus to the support in a position in which the acquisition apparatus is oriented so as to receive an image of both the retractor opening and of the colorimetric calibration chart and/or of the translucence calibration chart.

Abstract: A sulcular guard can be placed into the gingival sulculus surrounding a tooth to collect excess cement resulting from a replacement crown cementation procedure. The semi-rigid sulcular guard can have a generally “U” shaped cross-section with a central recess configured for collecting and containing the cement. Prior to cementing a crown on a prepared tooth, the guard may be inserted into the gingival sulculus surrounding the tooth. When the crown is pressed onto the tooth, excess cement, which is forced out from the bottom of the crown, can be collected and contained within the recess. Upon completion of the cementation, the guard, and all cement contained therein, may be removed leaving the gingival sulculus free of cement.

Abstract: A system and associated methodology for the generation of digital models that account for the adaptation of the shape of the patient's gingiva is provided. The exemplary system uses an initial scan of the patient's gingiva as a base model, taking into account the type and morphology of the teeth, the shape, orientation and movements of the roots inside the gingiva, and other factors for a more accurate prediction of the changes in the shape of the gingiva throughout every step of the treatment. In particular, the system proactively determines the areas of the model that will be covered by the aligner and prevents changes to such areas, whereas the shape of the model outside these areas is altered in a way to minimize the size of model and to add any necessary features for the manufacturing of the aligners.

Abstract: A method of constructing an anterior guidance package (AGP) equipped appliance, the AGP comprising a mandibular guidance component and a maxillary guidance component, and the appliance comprising a mandibular retentive piece configured to be placed about a mandibular arch of a user and a maxillary retentive piece configured to be placed about a maxillary arch of the user, the method comprising: maintaining of the mandibular guidance component in a correct orientation relative to the maxillary guidance component; indexing, while maintaining the mandibular guidance component in the correct orientation relative to the maxillary guidance component, the AGP onto the mandibular retentive piece and the maxillary retentive piece; and enabling, after indexing the AGP onto the mandibular and maxillary retentive pieces, the mandibular guidance component to move from the correct orientation relative to the maxillary guidance component.

Abstract: The present invention relates to a palatal and jaw expansion device comprising at least one screw, at least two blocks that are positioned on the screw so as to move on the screw, at least one stabilization rod whereon the blocks are seated, a movement mechanism disposed at the center of the screw and an arm that has a fixed end fixed to the movement mechanism perpendicularly to the horizontal axis where the screw extends and a free end and hat, when force is applied on the free end, rotates the movement mechanism whereon the arm is fixed and the screw around the horizontal axis where the screw extends, enabling the blocks to move on the screw.

Abstract: A frictionally-retained detachable dental attachment assembly or anchor device is designed to attach a dental appliance with a tooth root or implant. The assembly includes a denture attachment housing for securing in the dental appliance, an abutment attached with a tooth root or implant, and a compressible retention member with a first end in fixed attachment with the cap and a second end in snap engagement with the abutment via a frictionally-retained ball secured within a cavity of the abutment. The retention member is formed using a compressible material to allow the ball to compress and the retention member to flex while inserting the ball into the cavity. Additional friction-retained and fixed attachment configurations of the dental anchor device are provided, along with methods of securing a dental appliance in a subject's mouth by means of the friction-retained and fixed attachment dental anchor devices.

Abstract: A set of healing abutments includes a first healing abutment and a second healing abutment. The first healing abutment has an upper surface with a first code thereon. The first code is associated with a size of the first healing abutment. The second healing abutment has an upper surface with a second code thereon. The second code is associated with a size of the second healing abutment. The first healing abutment and the second healing abutment have the same size. The first code is different from the second code.

Abstract: The invention relates to a method for the production of a dental restoration from a blank, which has regions or layers of ceramic materials with differing compositions, under use of the method steps, filling of the ceramic materials into a mold, pressing of the ceramic materials to form a blank, removal of the blank from the mold, temperature treatment of the blank, wherein the ceramic materials are filling into the mold in such a way that layers and/or regions after temperature treatment have a profile that is available as a digital set.

Abstract: The invention relates to a denture, made of teeth, in particular prefabricated teeth, and of a denture base made of a gingival material, comprising cavities for teeth in which cavities for the teeth are mounted, in particular attached by bonding, characterized in that the denture base (12) is produced by a CAD/CAM process forming the cavities (20) for the teeth (14), and in that cervical areas (40a) of the teeth (14) extending through the basal surface (16, 18) of the denture base (12) are removed, in particular abraded or milled.

Abstract: Embodiments include dental appliances, dental appliance systems, and methods of making and using such appliances. In one embodiment, a dental appliance includes a shell having a number of cavities to receive one or more teeth, each cavity having an inner surface. Fewer than all cavities are scaled-up in size by a first selected percentage over one or more dimensions of a corresponding tooth surface to provide a uniform space between the cavity inner surface and the corresponding tooth surface.

Abstract: Described are implants and dilators useful in a sacral colpopexy procedure, and related methods. The present invention relates to systems, tools, and methods for treating pelvic organ prolapse by use of a pelvic implant to support pelvic tissue. The pelvic treatments include, for example, treatment of vaginal prolapse by laparoscopic or abdominal procedures.

Abstract: A sutureless ventral hernia meshing system and method of fixation is efficacious for fixating a surgical mesh panel to an abdominal wall for the purpose of hernia repair and prevention of hernia recurrence at the peripheral region of the mesh panel. The mesh panel comprises a hydrophilic face and a meshed face. A plurality of hollow anchors such as spikes or pins or hooks are disposed along the peripheral region of the mesh panel in a spaced apart relationship. A blunt quill or needle presses the hollow spikes or pins or hooks into the fascia around the hernia. The blunt quill or needle is removed after pressing the hollow pin into the fascia. In this manner, no sharp needle or suture is used. Tissue growth occurs in the cavity of the hollow spikes or pins or hooks to provide a sutureless anchor.

Abstract: A non-setting agent for positioning a surgical mesh prosthesis against a tissue defect during surgical hernia repair enables a surgeon to position the surgical mesh prosthesis at an optimal location against the tissue defect without pre-measuring suture location and pre-suturing. The surgical mesh prosthesis can be repositioned by removing and replacing, or by sliding, the mesh along the tissue defect without traumatizing the tissue. The positioning agent is provided with adhesion and lubricity characteristics providing an adhesion strength required to temporarily maintain the surgical mesh in place, otherwise unsupported, against tissue of a targeted tissue location, and providing a viscosity that permits removal and replacement, or slidable movement, of the surgical mesh along the tissue upon receipt of a non-gravitational external force applied to the surgical mesh so movement of the surgical mesh that is atraumatic to the tissue.

Abstract: A prosthesis for repairing a hernia defect includes a patch body, a hoisting frame releasably attachable to the patch body, and a tether attached to the hoisting frame with a free end extendable through the thickness of the patch body and accessible from the side of the patch body opposite to where the hoisting frame is releasably attached. The patch body and/or the hoisting frame includes a self-expanding support member. The hoisting frame includes a frame body with an outer frame component and a force translation component for directing pulling forces on the tether across the frame body. The outer frame component has a loop configuration to generally follow the patch periphery with overlapping end portions or a gap between free ends thereof. The force translation component is separable into multiple segments to facilitate withdrawal of the hoisting frame through an opening when released from the patch.

Abstract: An implantable permanent filter assembly (1) for deployment in a bifurcated vessel includes a main vessel and at least two branches. This assembly includes a filtering sleeve (2) formed of an expendable braided framework (20) able to expand from a radially compressed state in a delivery configuration to a radially expanded state. The filtering sleeve extends along an axis and defines a cylindrical lumen devoid of impermeable layer, having a distal end configured to extend toward the branches of the bifurcated vessel and a proximal end configured to extend toward away from the branches of the bifurcated vessel. The braided framework has a plurality of mesh layers (22,23,24) of wires (25) made of biocompatible material, forming a lattice with a plurality of wires of each layers. The lattice, when observed normal with respect to a wall of the implantable endoluminal prosthesis, defines polygonal openings.

Abstract: An embolic coil with a secondary, delivered shape utilizing regions of varying stiffness is described. In some embodiments, these regions of varying stiffness are created by utilizing a larger primary wind loop diameter to create selective regions with lower stiffness and higher flexibility. In some embodiments, these regions of higher flexibility correspond to inflection regions on a complex coil shape to ease deliverability of the coil during therapeutic procedures.

Abstract: A vena cava filter is described, having one or more frame members or an elongated member arranged in helical fashion. A plurality of filaments connect frame members or portions of the elongated member. The filaments may be made of suture material. Hooks may be placed on a free end of the filaments, along the length thereof, or on one or more frame members to engage the blood vessel wall and anchor the filter. A retrieval member may be positioned on the filter to facilitate withdrawal of the filter from the blood vessel.

Abstract: A peripheral vascular filter according to some aspects of the invention includes a filter body forming a cavity therein, the filter body having a proximal end and a distal end in a length-wise direction of the peripheral vascular filter, the filter body having an opening in the proximal end thereof; a spring system arranged proximal to the filter body and in mechanical connection with the filter body and with a filter wire, the spring system being stretchable along the length-wise direction; a plurality of retractor wires, each retractor wire having a distal end connected to the filter body, and a proximal end connected to spring system. In a deployed configuration, the spring system absorbs forces applied to the filter wire proximal to the filter body to prevent the peripheral vascular filter from becoming dislodged from a position in a peripheral vasculature.

Abstract: A method for use of a double-structured tissue implant or a secondary scaffold stand-alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A method of use of a stand-alone secondary scaffold implant or unit for treatment of tissue defects.

Abstract: According to various embodiments, there is provided a tissue scaffold device including a porous core including a plurality of fibres; and an outer portion at least substantially surrounding the porous core, the outer portion including a plurality of pores elongated along a longitudinal axis of the tissue scaffold device.

Abstract: The present disclosure provides devices and methods for treating the breast. The devices can include an acellular tissue matrix having a predefined shape. The shape can include a first edge with an S-shaped configuration and a second arcuate-shaped edge. The shape alternatively can include a first concave edge and a second convex edge.

Abstract: Devices and methods of treatment useful in implantation and post-implantation procedures are described. The devices and methods may be used to correct deformities and/or asymmetries in tissues near an implant, support tissues near an implant, and/or refine the shape of an area of the body after placement of an implant, for example. The method may include inserting a cannula into tissue adjacent to or near an implant of a patient, and delivering fat or other filler material(s) to the tissue, wherein the cannula is configured to prevent or otherwise minimize the risk of damaging the implant, e.g., a breast implant. The cannula may include an elongate member having a lumen therein, an atraumatic distal tip, and an opening disposed proximal to the distal tip, the opening being in fluid communication with the lumen for delivering the fat or other filler material(s).

Abstract: Various intraocular pseudophakic contact lenses are disclosed. For example, an intraocular pseudophakic contact lens can include a first optical lens and multiple anchors. The first optical lens is configured to at least partially correct a residual refractive error in an eye. The anchors are configured to be inserted through an anterior surface of an intraocular lens into lens material forming a second optical lens of the intraocular lens in order to secure the intraocular pseudophakic contact lens to the intraocular lens. The anchors can be configured to couple the intraocular pseudophakic contact lens to different types of intraocular lenses, including intraocular lenses not specifically designed to be coupled to or receive the intraocular pseudophakic contact lens. The intraocular pseudophakic contact lens could also include at least one drug-eluting device located on the first optical lens and configured to deliver at least one medication.

Abstract: Prosthetic capsular devices (e.g., bag, bowl, housing, structure, cage, frame) include technology devices such as a computer, virtual reality device, display device, WiFi/internet access device, image receiving device, biometric sensor device, game device, image viewers or senders, GPSs, e-mail devices, combinations thereof, and/or the like. The technology devices can be used in combination with an intraocular lens. The output from the technology device(s) can be fed to the retina of the user to provide a visual image, can be otherwise connected to the user, and/or can be used to control the properties of the intraocular lens or of the prosthetic capsular device.

Abstract: An intraocular lens (IOL) device comprising a first lens, a second lens and a circumferential haptic. The first lens comprises a pair of opposing and deformable surfaces and a cavity defined therebetween. The first lens has a first lens diameter. The second lens has a second lens diameter. The circumferential haptic has an outer peripheral edge and couples the first lens and the second lens. A main IOL cavity is defined by the circumferential haptic, the first lens and the second lens. The IOL device is resiliently biased to an unaccommodated state, characterized by the IOL device having a first diameter d1 in the absence of radial compressive forces exerted on the outer peripheral edge. The IOL device actuates to an accommodated state being characterized by a second diameter d2 in response to radial compressive forces exerted on the outer peripheral edge, wherein d1>d2.

Abstract: A method and system provide an ophthalmic device. The ophthalmic device includes an ophthalmic lens having anterior surface, a posterior surface and at least one diffractive structure including a plurality of zones. The at least one diffractive structure is for at least one of the anterior surface and the posterior surface. Each zone includes at least one echelette having a least one step height. The step height(s) are individually optimized for each zone. To compensate chromatic aberration of eye from distance to a range of vision, a greater than 2? phase step height may be employed and the step height(s) folded by a phase, which is an integer multiple of two multiplied by ?. Hence chromatic aberration of eye may be compensated to improve vision from distance to near.

Abstract: The present embodiments provide a prosthesis comprising first and second segments, and an axially extendable segment coupled to the first and second segments. A valve is coupled to at least one of the axially extendable segment or the second segment. The axially extendable segment comprises a first state in which the valve at least partially overlaps with the first segment, and the axially extendable segment comprises a second state in which the valve lacks an overlap with the first segment.

Abstract: In a representative embodiment, an implantable assembly for a native heart valve comprises a prosthetic heart valve and first and second inflatable bodies. The prosthetic heart valve can comprise a frame and prosthetic leaflets. The first inflatable body can comprise first and second end portions, wherein the first end portion is configured to be secured to tissue of the native heart valve at a first location, and the second end portion is configured to engage an outer surface of the prosthetic valve. The second inflatable body can comprise third and fourth end portions, wherein the third end portion is configured to be secured to tissue of the native heart valve at a second location, and the fourth end portion is configured to engage the outer surface of the prosthetic valve. The first and second inflatable bodies anchor the prosthetic valve within the annulus of the native heart valve.