Patents Issued in November 26, 2020
  • Publication number: 20200368519
    Abstract: A lead body having a defibrillation electrode positioned along a distal portion of the lead body is described. The defibrillation electrode includes a plurality of electrode segments spaced a distance apart from each other. At least one of the plurality of defibrillation electrode segments includes at least one coated portion and at least one uncoated portion. The at least one coated portion is coated with an electrically insulating material configured to prevent transmission of a low voltage signal (e.g., a pacing pulse) while allowing transmission of a high voltage signal (e.g., a cardioversion defibrillation shock). The at least one uncoated portion is configured to transmit both low voltage and high voltage signals. The lead may also include one or more discrete electrodes proximal, distal or between the defibrillation electrode segments.
    Type: Application
    Filed: August 11, 2020
    Publication date: November 26, 2020
    Inventors: Mark T. Marshall, Amy E. Thompson-Nauman, Melissa G.T. Christie, Gonzalo Martinez, Kevin R. Seifert
  • Publication number: 20200368520
    Abstract: A lead assembly and associated process include a lead and an integrated feature that facilitates extraction of the lead from the associated body passage. The integrated feature in one embodiment is a sheath received between the associated body passage and received over the lead. The sheath has a first portion extending from adjacent the proximal end to adjacent the distal end of the lead, where the first portion has an inner surface facing with the lead outer surface and the first portion having an outer surface facing radially outward from the lead outer surface. A second portion of the sheath extends from adjacent the distal end to adjacent the proximal end of the lead. The second portion has an inner surface received over the outer surface of the first portion, and the second portion further having an outer surface abutting an inner surface of the associated body passage that receives the lead therein. The integrated feature is alternatively a wire, band, or spoke assembly.
    Type: Application
    Filed: June 1, 2020
    Publication date: November 26, 2020
    Inventor: Majid Rashidi
  • Publication number: 20200368521
    Abstract: The disclosure relates to a bio-electronic interface comprising: a substrate; a plurality of micro-scale tissue-engagement-structures coupled to the substrate, in which each tissue-engagement-structure has a distal end providing a base on the substrate, in which each tissue-engagement-structures comprises one or more guidance-features configured to guide the growth of a plurality of cells; and one or more interface elements associated with each of the tissue-engagement-structures, each interface element configured to couple the one or more of the plurality of cells.
    Type: Application
    Filed: January 10, 2019
    Publication date: November 26, 2020
    Inventor: Benjamin Templeton Paul
  • Publication number: 20200368522
    Abstract: A method for treating neural disorders is provided, The method includes the following operation. A stimulation is delivered to a layer of a cortex of a patient with a neural disorder, wherein the stimulation is delivered to less than all layers of the cortex of the patient. In another method for treating neural disorders, a stimulation is delivered to a cortex of a patient with a neural disorder, wherein the stimulation delivered to one of a plurality of layers of the cortex is stronger than to other layers of the cortex. The system for treating neural disorder is also provided. The system includes a stimulation signal generator and a layer-specific stimulation means. The layer-specific stimulation means is coupled to the stimulation signal generator, configured to deliver a stimulation to a specific layer of a cortex of a patient with a neural disorder.
    Type: Application
    Filed: May 19, 2020
    Publication date: November 26, 2020
    Inventors: PIN CHANG, HSIN CHEN, YEN-CHUNG CHANG, SHIH-RUNG YEH
  • Publication number: 20200368523
    Abstract: An example system for exciting a selected set of motor neurons of a patient comprises one or more signal generators configured for generating a first electrical signal and a second electrical signal; a first set of wires configured to provide the first electrical signal to a first set of electrodes, wherein the first set of electrodes are configured for being secured to a first set of positions on the patient; a second set of wires configured to provide the second electrical signal to a second set of electrodes, wherein the second set of electrodes are configured for being secured to a second set of positions on the patient; and a controller configured to control operation of the one or more signal generators. The first electrical signal is a periodic signal of a first frequency. The second electrical signal is a periodic signal of a second frequency. The first frequency and the second frequency differ by a non-zero frequency difference.
    Type: Application
    Filed: September 5, 2018
    Publication date: November 26, 2020
    Inventors: David D. FULLER, Kevin OTTO, Michael D. SUNSHINE
  • Publication number: 20200368524
    Abstract: An insertion assembly for inserting a neural implant into target neural tissue. The insertion assembly includes a horn connecting to a vibrational actuator. A horn tip is configured to support an implant for insertion, such as the base of an implant having electrode(s). An implant stabilizer is displaceably affixed to the horn at a connection point for secure mounting while permitting flexing of the implant stabilizer. The implant stabilizer includes a first end positionable proximate to the horn tip and contacting the implant, and an opposite second end that may be selectively moved by force to adjust the position of the first end relative to the horn tip. A biasing member contacts the horn tip and first end of the implant stabilizer and urges the first end toward the horn tip to releaseably secure the implant to the horn tip. The biasing member may be selectively removed from the assembly.
    Type: Application
    Filed: April 13, 2020
    Publication date: November 26, 2020
    Applicant: Actuated Medical, Inc.
    Inventors: Roger B. Bagwell, Ryan S. Clement, Natasha N. Tirko, Jenna K. Greaser
  • Publication number: 20200368525
    Abstract: The present disclosure provides a method for treating cancer in a patient harboring an EGFR-expressing tumor and/or tumor cell, such as glioblastoma, comprising the combination of (i) applying an AC electric field to a target area, wherein the target area comprises an EGFR-expressing tumor or cancer cell); and (ii) administering an effective amount of depatuxizumab mafodotin.
    Type: Application
    Filed: November 19, 2018
    Publication date: November 26, 2020
    Inventors: David MAAG, Moshe GILADI, Rosa S. SCHNAIDERMAN, Einav ZEEVI, Eilon KIRSON
  • Publication number: 20200368526
    Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
    Type: Application
    Filed: August 13, 2020
    Publication date: November 26, 2020
    Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
    Inventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
  • Publication number: 20200368527
    Abstract: A wearable device combines its existing functions (e.g., a headphone) with non-invasive autonomic modulation using tragus or other external auditory meatus stimulation. The wearable device can output audio to a user, such as music, podcast, etc., and further provide modulation of the vagus nerve via tragus stimulation or other external auditory meatus stimulation to treat various diseases.
    Type: Application
    Filed: May 20, 2020
    Publication date: November 26, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Samuel J. Asirvatham
  • Publication number: 20200368528
    Abstract: Modulation of neural signaling of an eye-related sympathetic nerve can mitigate choroidal neovascularization (CNV) in the eye, and this provides a way of treating eye disorders, such as ocular neovascular diseases.
    Type: Application
    Filed: July 27, 2018
    Publication date: November 26, 2020
    Applicants: Galvani Bioelectronics Limited, University of Southern California
    Inventors: Arun SRIDHAR, Andrew C WEITZ, Victor Eugene PIKOV, Alessandra GIAROLA, Mark HUMAYUN
  • Publication number: 20200368529
    Abstract: This document discusses, among other things, systems and methods to provide a paresthesia therapy to a patient using an implantable neuromodulation system, wherein providing the paresthesia therapy may include delivering to the patient an electrical waveform having a duration and a distribution of frequencies in the range of 0.001 kHz to 20 kHz, wherein the distribution of frequencies includes a first frequency group of one or more frequencies and a second frequency group of one or more frequencies, and wherein the patient continuously experiences paresthesia throughout the duration of the electrical waveform.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Inventors: Jordi Parramon, Que T. Doan
  • Publication number: 20200368530
    Abstract: A method for treating movement disorders is provided. The method includes the following operations. A central nervous signal of a patient with movement disorders is recorded. A first stimulation is delivered from a stimulator to the patient when an oscillation episode in a range of from about 3 Hz to about 20 Hz is observed in the central nervous signal. The first stimulation is adapted according to a measurable feature of the oscillation episode. The system for treating movement disorders is also provided.
    Type: Application
    Filed: May 19, 2020
    Publication date: November 26, 2020
    Inventors: PIN CHANG, HSIN CHEN, YEN-CHUNG CHANG, SHIH-RUNG YEH
  • Publication number: 20200368531
    Abstract: Modulation of neural signaling of an eye-related sympathetic nerve can decrease the levels of pro-inflammatory cytokines in the eye, and this provides a way of treating eye disorders, such as ocular neovascular diseases.
    Type: Application
    Filed: July 27, 2018
    Publication date: November 26, 2020
    Applicants: Galvani Bioelectronics Limited, University of Southern California
    Inventors: Arun SRIDHAR, Andrew C WEITZ, Victor Eugene PIKOV, Alessandra GIAROLA, Mark HUMAYUN
  • Publication number: 20200368532
    Abstract: Peripheral nerve field stimulation (PNFS) may be controlled based on detected physiological effects of the PNFS, which may be an efferent response to the PNFS. In some examples, a closed-loop therapy system may include a sensing module that senses a physiological parameter of the patient, which may be indicative of the patient's response to the PNFS. Based on a signal generated by the sensing module, the PNFS may be activated, deactivated or modified. Example physiological parameters of the patient include heart rate, respiratory rate, electrodermal activity, muscle activity, blood flow rate, sweat gland activity, pilomotor reflex, or thermal activity of the patient's body. In some examples, a patient pain state may be detected based on a signal generated by the sensing module, and therapy may be controlled based on the detection of the pain state.
    Type: Application
    Filed: August 5, 2020
    Publication date: November 26, 2020
    Inventors: Gary W. King, Steven M. Goetz, Andrew H. Houchins, Jeffrey T. Keacher, Jordan J. Greenberg, Kenneth T. Heruth, Mark S. Lent, Paul W. Wacnik
  • Publication number: 20200368533
    Abstract: Methods and systems for monitoring and regulating temperatures of neurostimulator programmers are provided herein. A neurostimulator programmer may include one or more sensors that may detect one or more temperatures associated with the neurostimulator programmer. Each of the one or more sensors may be associated with one or more respective threshold values. When these threshold values are exceeded, one or more courses of actions may be taken by the neurostimulator programmer. For example, the neurostimulator programmer may reduce functionality of one or more heat-generating components, increase monitoring of temperature, and/or initiate shutdown of the neurostimulator programmer. In some cases, two or more such methods may be performed simultaneously, for example, one method to deal with high temperatures and another method to deal with particularly excessive temperatures.
    Type: Application
    Filed: May 22, 2020
    Publication date: November 26, 2020
    Inventors: Charles Borlase, Prabodh Mathur
  • Publication number: 20200368534
    Abstract: Systems, devices, and methods for delivering one or more electrical pulses to a target region within a patient's body are disclosed herein. An implantable neurostimulator for delivering such one or more electrical pulses can include a hermetic housing made of a biocompatible material, an energy storage feature, and at least one lead. The implantable neurostimulator can further include stimulation circuitry that can include a first circuit and a second circuit. The first circuit can include an adjustable resistance element having a first terminal and a second terminal, a first switch coupled to the first terminal of the adjustable resistance element and selectively coupleable with a stimulation-voltage node and a ground node, a second switch selectively coupling the a first one of the plurality of electrodes to one of: the second terminal of the adjustable resistance element; and the stimulation-voltage node.
    Type: Application
    Filed: May 19, 2020
    Publication date: November 26, 2020
    Inventor: Rabih Nassif
  • Publication number: 20200368535
    Abstract: A pacemaker having a motion sensor delivers atrial-synchronized ventricular pacing by detecting events from a signal produced by the motion sensor and delivering ventricular pacing pulses at a rate that tracks the rate of the detected events. The pacemaker is configured to confirm atrial tracking of the ventricular pacing pulses by determining if detected events from the motion sensor signal are atrial events. The pacemaker is configured to adjust a control parameter used for detecting events from the motion sensor signal if atrial tracking is not confirmed.
    Type: Application
    Filed: August 14, 2020
    Publication date: November 26, 2020
    Inventors: Todd J. SHELDON, Wade M. DEMMER, Greggory R. HERR
  • Publication number: 20200368536
    Abstract: A computer implemented method and system for labeling types of heart arrhythmias based on cardiac activity are provided. The method is under control of one or more processors of an implantable medical device (IMD) configured with specific executable instruction. The method obtains cardiac activity (CA) signals at electrodes of the IMD during cardiac beats, declares a ventricular tachycardia (VT) episode based on the CA signals and obtains acceleration signatures, at an accelerometer of the IMD, indicative of heart sounds generated during the cardiac beats. The method analyzes an S1 characteristic of interest (COI) from the acceleration signature to identify the VT episode as a stable or non-stable VT episode and labels the VT episode as stable or non-stable based on the analyzing operation.
    Type: Application
    Filed: May 20, 2019
    Publication date: November 26, 2020
    Inventors: Jong GILL, Gene A. BORNZIN
  • Publication number: 20200368537
    Abstract: In some examples, a feedthrough assembly for a medical device may include a ferrule. The ferrule defines an aperture extending through the ferrule from an outer end surface defined by the ferrule to an end inner end surface defined by the ferrule. The aperture includes a first portion having a first diameter and a second portion having a second diameter less than the first diameter. The aperture defines a longitudinal axis extending therethrough and the ferrule defines a ledge between the first and second portions of the aperture that extends radially inward toward the longitudinal axis. The feedthrough assembly further may include a conductive pin within the aperture and an insulating member surrounding at least a portion of the pin. The insulating member may electrically insulate the conductive pin from the ferrule, and the ledge and a surface of the insulating member adjacent the ledge may define a space therebetween.
    Type: Application
    Filed: May 23, 2019
    Publication date: November 26, 2020
    Inventors: Michael J. Nidelkoff, Lance B. Lohstreter, Brad C. Tischendorf, Paul B. Aamodt, Matthew J. Sanders
  • Publication number: 20200368538
    Abstract: Embodiments of the present technology described herein are directed to implantable systems for performing cardiac resynchronization therapy (CRT), methods for use therewith, and leadless pacemakers for use therewith. Such a system can include a first leadless pacemaker configured to be implanted in or on the right atrial (RA) chamber and selectively pace the RA chamber, a second leadless pacemaker configured to be implanted in or on the right ventricular (RV) chamber and selectively pace the RV chamber, and a third leadless pacemaker configured to be implanted in or on the left ventricular (LV) chamber and selectively pace the LV chamber, wherein one of the leadless pacemaker is designated a master leadless pacemaker. In certain embodiments, the master leadless pacemaker determines a VV delay and an AV delay and coordinates CRT using such delays.
    Type: Application
    Filed: May 24, 2019
    Publication date: November 26, 2020
    Inventor: Xiaoyi Min
  • Publication number: 20200368539
    Abstract: Delivery devices, systems, and methods for delivering implantable leadless pacing devices are disclosed. An example delivery device may include an intermediate tubular member and an inner tubular member slidably disposed within a lumen of the intermediate tubular member. A distal holding section may extend distally of a distal end of the intermediate tubular member and define a cavity therein for receiving an implantable leadless pacing device. The device may be configured to enable fluid flushing of the delivery device prior to use, to remove any air from within the device as well as providing the option of fluid flow during use of the delivery device.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Applicant: CARDIAC PACEMAKERS, INC.
    Inventors: BRIAN SOLTIS, BENJAMIN J. HAASL, JAMES P. GOODMAN, VINCENT P. HACKENMUELLER
  • Publication number: 20200368540
    Abstract: Techniques for minimizing rate of depletion of a non-rechargeable power source, to extend the operational lifetime of an implantable medical device that includes the non-rechargeable power source, by enforcing operational-mode-specific communication protocols whereby inter-device communication between the implantable medical device and another implantable medical device is such that level of power draw from the non-rechargeable power source by the implantable medical device is less than level of power draw from the rechargeable power source by the another implantable medical device for the implantable medical devices to engage in communication with each other.
    Type: Application
    Filed: August 11, 2020
    Publication date: November 26, 2020
    Inventors: Wade M. Demmer, Yong K. Cho, Michael F. Hess, Todd J. Sheldon
  • Publication number: 20200368541
    Abstract: An ear-piece assembly includes (i) an antenna portion enclosing a transmitting antenna configured to send one or more input signals containing electrical energy to a passive implantable neural stimulator device such that the passive implantable neural stimulator generates one or more stimulation pulses suitable for stimulating a neural structure in the craniofacial region solely using the electrical energy in the input signals; and (ii) an enclosure coupled to the antenna portion, wherein enclosure is sized and shaped to be mounted on a helix portion of an ear such that, when worn by a patient, weight from the enclosure is distributed over the helix portion of the ear for the enclosure to rest thereon, wherein the enclosure comprises (i) a controller module configured to provide the one or more input signals to the transmitting antenna, and (ii) a battery adapted to provide energy to the ear-piece assembly.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Inventors: Laura Tyler Perryman, Chad David Andresen, Graham Patrick Greene
  • Publication number: 20200368542
    Abstract: A medical device stores a set of stimulation profiles, wherein each stimulation profile of the set of stimulation profiles is associated with a set of values for stimulation parameters; selects from the set of stimulation profiles, one or more active stimulation profiles; produces, by a stimulation generator, multiple electrical pulses based on the one or more active stimulation profiles; and separately controls parameter values of respective individual pulses of the multiple pulses.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Inventors: Erik J. Peterson, Mandla Shongwe
  • Publication number: 20200368543
    Abstract: Disclosed herein are implantable medical devices and systems, and methods for used therewith, that selectively perform atrial overdrive pacing while an intrinsic atrial rate of a patient is within a specified range. Such a method can involve measuring intervals between a plurality of intrinsic atrial depolarizations that occur during a specified period, and classifying intrinsic atrial activity as stable or unstable based on the measured intervals. In response to classifying the intrinsic atrial activity as stable, atrial overdrive pacing is performed. In response to classifying the intrinsic atrial rate as unstable, atrial overdrive pacing is not performed (i.e., is abstained from being performed). Over time, effectiveness of performing atrial overdrive pacing using various different atrial interval shorting deltas are recorded in a log and updated, and the log is used to determine a preferred rate at which to perform atrial overdrive pacing for various different measured intervals.
    Type: Application
    Filed: August 14, 2020
    Publication date: November 26, 2020
    Applicant: Pacesetter, Inc.
    Inventor: Xing Pei
  • Publication number: 20200368544
    Abstract: An apparatus has advanced amplifier Classes and low pass filter technologies for using software generated ascending or level waveforms that are effective to apply cardiac defibrillation and cardioversion waveforms which significantly reduce damage to the heart muscle or to treat congestive heart failure. The apparatus comprises a waveform energy control system for delivering software generated waveforms comprising one or more differentially driven Class D amplifier sections or differentially driven PWM Class D and Class B or any other class amplifier sections, wherein each Class D amplifier section produces Phase 1 ascending waveforms and has a programmable impedance tracking lowpass filter (LPF) and wherein the Class B or any other class amplifier section delivers hard-switched Phase 2 waveforms.
    Type: Application
    Filed: June 8, 2020
    Publication date: November 26, 2020
    Inventors: RAYMOND E. IDEKER, RICHARD RUSE, SCOTT BOHANAN
  • Publication number: 20200368545
    Abstract: This invention corresponds to an electrical and magnetic tissue stimulation device comprising a multi-source distribution circuit, a decoupled output stage circuit connected to the multi-source distribution circuit and to a control unit; the control unit is connected to the multi-source distribution circuit and to the decoupled output stage circuit, where the control unit generates PE and Out outputs for electrical and magnetic stimulation of a tissue. The invention also has a multi-source distribution circuit that comprises a control unit connected to a source output selector. A voltage regulator circuit is connected to a current limiter. The current limiter is connected to a capacitor, to a capacitor bank and to the source output sector, wherein the control unit controls the source output selector by means of an output control signal bus, the source output selector connects or disconnects one or more capacitors from the capacitor bank.
    Type: Application
    Filed: November 17, 2018
    Publication date: November 26, 2020
    Applicant: PANACEA QUANTUM LEAP TECHNOLOGY LLC
    Inventor: Francisco Javier VELASCO VALCKE
  • Publication number: 20200368546
    Abstract: An assay procedure is described, which allows for the assessment in humans and in animals of a life force energy, which the Applicant refers to as KELEA, being an abbreviation for kinetic energy limiting electrostatic attraction KELEA serves as a non-food calorie source of cellular energy in what the Applicant calls the alternative cellular energy (ACE) pathway. A deficiency in the ACE pathway can contribute to various illnesses. Conversely, an adequate ACE pathway can assist in the healing process. The measurement of KELEA is based on the earlier finding that it can add to the measured weight of dipolar materials, including those containing cellulose. This later grouping extends to paper. KELEA can be transferred to, or alternatively, withdrawn from, paper, as determined by an increase or a decrease, respectively, in the measured weight of a sheet of paper.
    Type: Application
    Filed: May 23, 2019
    Publication date: November 26, 2020
    Inventor: William John Martin
  • Publication number: 20200368547
    Abstract: A method for treating a disease, disorder, or condition in a subject in need thereof, by administering either or both of (i) at least one photoactivatable pharmaceutical agent, or (ii) a first plurality of energy-emitting particles, into the subject in a region of the disease, disorder, or condition, whereby the administering is performed through inhalation; and applying an applied electromagnetic energy to the subject, wherein the applied electromagnetic energy directly or indirectly activates the at least one photoactivatable pharmaceutical agent, when present, and wherein when the first plurality of energy-emitting particles is present, the first plurality of energy-emitting particles absorbs the applied energy and emits an emitted electromagnetic energy, wherein the emitted electromagnetic energy interacts directly with the region of the disease, disorder, or condition or activates the at least one photoactivatable pharmaceutical agent.
    Type: Application
    Filed: April 28, 2020
    Publication date: November 26, 2020
    Applicants: IMMUNOLIGHT, LLC., DUKE UNIVERSITY
    Inventors: Frederic A. BOURKE, JR., Harold WALDER, Zakaryae FATHI, Michael J. THERIEN, Mark W. DEWHIRST, Ian N. STANTON, Jennifer Ann AYRES, Diane Renee FELS, Joseph A. HERBERT
  • Publication number: 20200368548
    Abstract: Exemplary system and method are provided for affecting nail growth rate, which can use a light dosage and a wavelength of light to affect a growth rate of a nail of a subject. For example, it is possible to detect a presence of a nail using, e.g., a presence detector. The nail can be irradiated over a treatment time with a light having a wavelength and a power, e.g., using a narrowband light source. Further, using a controller, it is possible to control one or more of the power and the treatment time to irradiate the nail with a light dosage that is within a biphasic light dosage range bounded by a lesser light dosage and a greater light dosage. The wavelength of the light and the light dosage can be configured to affect a growth rate of the nail. Further, it is possible to document or record (e.g., to a computer file) and/or analyze at least one parameter related to the light dosage, e.g., possibly using the controller and/or a computer device.
    Type: Application
    Filed: April 2, 2020
    Publication date: November 26, 2020
    Inventor: Vincent Zuo
  • Publication number: 20200368549
    Abstract: A light therapy apparatus includes a pad comprising at least a first layer and a second layer and a side scattering light guide mounted between the first layer and the second layer and having a first end and a second end. The first end and the second end extend in parallel with each other externally from the pad, the side scattering light guide extends from at least one of the first end or the second end in a sinusoidal shape or an inward extending circular spiral between the first layer and the second layer, and at least one of the first layer or the second layer is translucent.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Inventor: John Stephan
  • Publication number: 20200368550
    Abstract: Lighting systems, methods, and devices for protecting human circadian neuroendocrine function during night use are described. Suitable lighting conditions can be provided for a working environment while protecting the circadian neuroendocrine systems of those occupying the illuminated workplace during the night. Lighting systems, methods, and devices can provide substantive attenuation of the pathologic circadian disruption in night workers. Lighting systems, methods, and devices can attenuate the specific bands of light implicated in circadian disruption. LED lighting systems, methods, and devices can provide increased intensity at a different portion of the spectrum than conventional LEDs, providing a useable white light even when unfavorable portions of the wavelength are attenuated by a notch filter.
    Type: Application
    Filed: August 5, 2020
    Publication date: November 26, 2020
    Inventors: Martin Christopher Moore-Ede, Rebecca Mary Chacko, Anneke Marlies Heitmann, Robert Frederic Casper, Robert Frank Karlicek, JR., Doros Platika, Udo Trutschel
  • Publication number: 20200368551
    Abstract: Described here are systems, devices, and methods for imaging and radiotherapy procedures. Generally, a radiotherapy system may include a radiotransparent patient platform, a radiation source coupled to a multi-leaf collimator, and a detector facing the collimator. The radiation source may be configured to emit a first beam through the collimator to provide treatment to a patient on the patient platform. A controller may be configured to control the radiotherapy system.
    Type: Application
    Filed: June 2, 2020
    Publication date: November 26, 2020
    Inventors: Rostem BASSALOW, Manat MAOLINBAY, Brent HARPER
  • Publication number: 20200368552
    Abstract: A method for simulating a particle transport may include recording transport paths of inputted particles and determining an uncertainty of each of lattice cells based on the transport paths of each batch of the inputted particles, a lattice cell being a qualified lattice cell if an uncertainty of the lattice cell does not exceed a first threshold; determining a standard-reaching rate of lattice cells in a region of interest (ROI), the ROI including at least one lattice cell, the standard-reaching rate of lattice cells in the ROI being equal to a ratio of the number of qualified lattice cells to a total number of lattice cells in the ROI; and if the standard-reaching rate of lattice cells in the ROI exceeds a second threshold, stopping inputting particles, and outputting the transport paths of the inputted particles.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Gui LI, Yin TANG, Shaoqiang YE, Juan LIU
  • Publication number: 20200368553
    Abstract: Methods are provided for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject. One such method comprises: determining a dose modification voxel for which it is desired to modify the dose value and a corresponding magnitude of desired dose modification; for each of a plurality of beams: (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing the projection of the beamlet into space; and (ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; modifying the intensity values of at least one of the dose-change beamlets; and updating the achievable dose distribution estimate to account for the modified intensity values of the at least one of the dose-change beamlets.
    Type: Application
    Filed: August 13, 2020
    Publication date: November 26, 2020
    Inventor: Karl OTTO
  • Publication number: 20200368554
    Abstract: A radiation therapy system includes a radiation source, a processor, a flexible pressure sensing matrix, and a pressure sensing device. The radiation source emits a radiation beam to a target region of a patient for treatment. The processor is coupled to the radiation source for adjusting an incident angle and intensity of the radiation beam. The flexible pressure sensing matrix is placed at an object for detecting an amount of movement and an amount of rotation of the object. The pressure sensing device is coupled to the flexible pressure sensing matrix for receiving the amount of movement and the amount of rotation of the object. When the amount of movement or the amount of rotation exceeds a first preset amount, the processor controls the radiation source to suspend treatment.
    Type: Application
    Filed: November 6, 2019
    Publication date: November 26, 2020
    Inventors: LIANG-HSIANG WU, NGOT-SWAN CHONG, CHIH-CHING CHANG, YI-CHING LIU, MING-HSUN HSU
  • Publication number: 20200368555
    Abstract: A method and apparatus for position detection, and a radiotherapy system are provided. The radiotherapy system includes: a treatment couch, a positioning apparatus, an optical tracking system and a computer; the positioning apparatus disposed on the treatment couch, and at least one reference point provided on the positioning apparatus; the optical tracking system disposed above the treatment couch and configured to detect relative positioning between a mark point set on a treated part of a patient and the reference point, determine deviation between the relative and reference positions, and send the deviation to the computer. The computer is configured to determine whether to adjust a position of the treatment couch based on the deviation and deviation range. The system provided by the present disclosure avoids the influence of patient movement on the accuracy of treatment, and prevents a treatment beam from damaging normal tissues of the patient.
    Type: Application
    Filed: July 16, 2020
    Publication date: November 26, 2020
    Inventors: Tianchang GOU, Jinsheng LI, Hao YAN, Liang WANG, Kaiqiang FU, Pengfei ZHANG, Xiaojun YUE, Bing HE
  • Publication number: 20200368556
    Abstract: An example particle therapy system may include: a synchrocyclotron to produce a particle beam; a scanner to move the particle beam in one or more dimensions relative to an irradiation target; and an energy degrader that is between the scanner and the irradiation target. The energy degrader may include multiple plates that are movable relative to a path of the particle beam, with the multiple plates each being controllable to move while in the path of the particle beam and during movement of the particle beam. An aperture may be between the energy degrader and the irradiation target. The aperture being may be to trim the particle beam prior to the particle beam reaching the irradiation target.
    Type: Application
    Filed: June 8, 2020
    Publication date: November 26, 2020
    Applicant: Mevion Medical Systems, Inc.
    Inventors: Gerrit Townsend Zwart, Mark R. Jones, James Cooley, Adam Molzahn
  • Publication number: 20200368557
    Abstract: Disclosed herein are radiation therapy systems and methods. These radiation therapy systems and methods are used for emission-guided radiation therapy, where gamma rays from markers or tracers that are localized to patient tumor regions are detected and used to direct radiation to the tumor. The radiation therapy systems described herein comprise a gantry comprising a rotatable ring coupled to a stationary frame via a rotating mechanism such that the rotatable ring rotates up to about 70 RPM, a radiation source (e.g., MV X-ray source) mounted on the rotatable ring, and one or more PET detectors mounted on the rotatable ring.
    Type: Application
    Filed: May 29, 2020
    Publication date: November 26, 2020
    Inventors: Brent HARPER, Robert WIGGERS, David LARKIN, David MEER, David NETT, Rostem BASSALOW, Peter OLCOTT, Chris JULIAN, Brent DOLAN, William Jorge PEARCE
  • Publication number: 20200368558
    Abstract: The makeup removal composition includes at least one branched or linear, liquid alkane with carbon chain length of C11 to C20, at least one polar emollient with molecular weight of 400 g/mol or less, at least one polymeric thickener for water-based system, and at least one surfactant in a water-based emulsion/suspension system comprising oil and water phases, the water phase including water present from about 70% to about 85% by weight of the composition. Articles include the composition infused in a water-insoluble substrate formed from synthetic materials or formed from natural biodegradable and sustainably sourced natural originated fiber, natural fiber, or regenerated or recycled natural fiber.
    Type: Application
    Filed: May 25, 2019
    Publication date: November 26, 2020
    Inventors: Catherine CHIOU, Ryuji HARA, Jean-Pascal HIRT
  • Publication number: 20200368559
    Abstract: One variation of a method includes: accessing a skin type of a user; predicting a first set of locations occupied by the user during a first future time interval; based on historical ultraviolet irradiance data and the first future time interval, calculating a first predicted unprotected ultraviolet radiation exposure of the user during the first future time interval; calculating a maximum allowable ultraviolet radiation exposure for periods within the first future time interval based on the skin type of the user; calculating a first minimum sun protection factor predicted to reduce the first predicted unprotected ultraviolet radiation exposure to less than the maximum allowable ultraviolet radiation exposure; selecting a first sunscreen formula characterized by a first sun protection factor greater than the first minimum sun protection factor; and shipping the first volume of the first sunscreen formula to the user prior to the first future time interval.
    Type: Application
    Filed: August 12, 2020
    Publication date: November 26, 2020
    Inventor: Andrew Poutiatine
  • Publication number: 20200368560
    Abstract: A system and method may allow a person to rotate a skin care product based on the current climate to help skin transition to and react to changes in temperature and humidity the air. For example, each moisturizer may be formulated to support skin needs for a specific climate, such as tropical climate (i.e., humid and hot air), a desert climate (i.e., dry and hot air), a temperate climate (i.e., normal and mild air), and/or a polar climate (i.e., cold and dry air).
    Type: Application
    Filed: August 14, 2020
    Publication date: November 26, 2020
    Inventor: Ulrike Haslacher
  • Publication number: 20200368561
    Abstract: Provided is an oxygen candle starting device, comprising a pull line column (17) and a percussion cap (15), wherein a pull line hole (155) is provided in the pull line column in an axial direction of the pull line column, a percussion cap cavity (154) is provided inside one end of the pull line column, a fire-preventing cavity is provided inside the other end of the pull line column, and the pull line hole passes through the fire-preventing cavity and the percussion cap cavity; the percussion cap is mounted in the percussion cap cavity, and sand grains (16) are packaged in the fire-preventing cavity.
    Type: Application
    Filed: October 25, 2018
    Publication date: November 26, 2020
    Applicant: SHAANXI STAR EXPLOSION SAFETY POLYTRON TECHNOLOGIES INC
    Inventors: Xinguo WEN, Aiping MA
  • Publication number: 20200368562
    Abstract: A firefighting water garment consists of a reinforced cotton fabric with combing manufactured through weaving of doubled yarn with loose end with an area weight approximately 346 g/m2 which is able to absorb up to six-times more liquid than it weights. The fabric is soaked with a water solution that consists of 50% of water, at least, of 2.7 to 50% of extinguishing agent and of 1 to 10% of a component reflecting heat radiation. Another necessary component is powder titanium dioxide which reflects heat radiation perfectly. Evaporation of water from the suit occurs under presence of fire, and the water starts to cool surface of the fabric and thus prevents overheating of the organism. This way marked extension of time for suit exposure in the fire and prevention of rise of dangerous burns on skin is achieved.
    Type: Application
    Filed: December 18, 2018
    Publication date: November 26, 2020
    Inventors: Adam Lucanik, Petra Gottwald
  • Publication number: 20200368563
    Abstract: Techniques are described for monitoring and controlling fall protection equipment. For example, the techniques of this disclosure may be used to monitor the connection status of fall protection equipment, e.g., whether or not the fall protection equipment is connected to a support structure. The techniques described in the disclosure may determine whether the fall protection equipment is connected to a support structure based on changes in a resonant frequency of an electronic circuit of an inductive sensor within the fall protection equipment. The inductive sensor may be formed from sets of one or more coils, where a first set of one or more coils and a second set of one or more coils are wound in opposite directions.
    Type: Application
    Filed: February 6, 2019
    Publication date: November 26, 2020
    Inventors: Anthony J. Nowicki, Ronald D. Jesme, Judd D. Perner, Scott E. Brigham, Jeffrey T. Keacher, Mohsen Salehi, Jonathan J. Lepp
  • Publication number: 20200368564
    Abstract: A system for protecting a structure in imminent threat of a fire hazard, the system includes a fire protective cover formed from a plurality of side-cover portions and a plurality of roof-cover portions, each of the side and roof -cover portions being adapted to attach to one or more eaves of the structure via a plurality of attachment elements, for example, clamps and the like. In addition, an optional cable may be engaged around a periphery of the structure and secured for holding the side-cover portions against side sections of the structure. A method is described for installing the system and fire protective cover thereof.
    Type: Application
    Filed: May 8, 2020
    Publication date: November 26, 2020
    Applicant: URBNTEK LLC
    Inventor: Charles Castelo
  • Publication number: 20200368565
    Abstract: A locomotive-mounted power battery pack fire safety control system includes a power battery pack, a power battery management system main controller, a rolling stock microcomputer system and a rolling stock display screen. The power battery pack is an enclosed installation isolated from external air. An inert gas injection pipe, a smoke detector and a temperature detector are arranged at the top end inside the power battery pack. An inert gas storage device is arranged outside the power battery pack. The inert gas storage device is connected with the inert gas injection pipe. A pressure detector and an inert gas injection control switch are arranged in turn on a pipeline through which the inert gas storage device discharges an inert gas to the power battery pack. The pressure detector and the inert gas injection control switch are connected with the rolling stock microcomputer system.
    Type: Application
    Filed: November 1, 2018
    Publication date: November 26, 2020
    Inventors: YuFa MENG, DingKang YE, PingHua WANG
  • Publication number: 20200368566
    Abstract: A wildland urban interface (WUI) firefighting apparatus is provided in the form of a four-wheel or all-wheel drive pumper truck that merges the high-clearance and off road capability of a Type 3 wildland pumper truck with the functionality, exceptional handling, mobility and storage capacity of a Type 1 pumper truck. The truck can include a short front overhang chassis yielding a 20+ degree angle of approach and an optional 20+ degree angle of departure. The truck can include a compact water distribution system including a narrow discharge manifold plumbed to an engine PTO driven primary pump and optional portable secondary pump, which can operate during pump and roll firefighting procedures. The discharge manifold can be coupled to electronic valves operated via a control panel, and can be so narrow that it can contribute to shortening the truck's wheelbase.
    Type: Application
    Filed: August 13, 2020
    Publication date: November 26, 2020
    Inventors: Kenneth C. Lenz, JR., Kevin J. Longhurst
  • Publication number: 20200368567
    Abstract: A fire suppression system in which the water supply line is fitted with repeating arrays or groups of sprinkler heads. Each array is composed of at least two side-discharge sprinklers. The side-discharge sprinklers in each array are aimed so that their coverage areas point in opposite directions. Each side-discharge sprinkler includes a lateral heat shield. The lateral heat shield has a concave heat-concentering side that focuses radiant heat toward the sprinkler's trigger, and a convex heat-scattering side that disperses radiant heat away from the trigger. In some embodiments, the array can include one or more vertical-discharge sprinklers. The vertical-discharge sprinkler may include a heat collector to facilitate early activation of its trigger. The fire suppression system is advantageous in high-challenge applications like facilities where large quantities of combustible items are stored in close proximity, such as in warehouses and attics.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Inventor: Jeffrey J. Pigeon
  • Publication number: 20200368568
    Abstract: An electric heater fire extinguishing strategy customization mechanism includes: a timing device for outputting the current operation time; a real-time display device installed onto an integrated circuit board of the electric heater and connected to the timing device for receiving the current operation time and displaying a red string corresponding to the real-time display and too-long operation information of when the current operation time exceeds a limit; a position sensing device installed onto the dot-matrix imaging mechanism for detecting the current position of the dot-matrix imaging mechanism, determining the difference between the current position and a predetermined fixed position, wherein the difference includes a horizontal change and a vertical change, and issuing a jitter sensing signal when the horizontal change changes between positive and negative values or the vertical change changes between positive and negative values. The electric heater includes a fire extinguishing function.
    Type: Application
    Filed: April 12, 2019
    Publication date: November 26, 2020
    Inventor: Gaoli Ge