Abstract: Aspects of the present disclosure provide improved techniques for imaging a subject's retina fundus. Some aspects relate to an imaging apparatus that may be substantially binocular shaped and/or may house multiple imaging devices configured to provide multiple corresponding modes of imaging the subject's retina fundus. Some aspects relate to techniques for imaging a subject's eye using white light, fluorescence, infrared (IR), optical coherence tomography (OCT), and/or other imaging modalities that may be employed by a single imaging apparatus. Some aspects relate to improvements in white light, fluorescence, IR, OCT, and/or other imaging technologies that may be employed alone or in combination with other techniques. Some aspects relate to multi-modal imaging techniques that enable determination of a subject's health status.

Abstract: Aspects of the present disclosure provide improved techniques for imaging a subject's retina fundus. Some aspects relate to an imaging apparatus that may be substantially binocular shaped and/or may house multiple imaging devices configured to provide multiple corresponding modes of imaging the subject's retina fundus. Some aspects relate to techniques for imaging a subject's eye using white light, fluorescence, infrared (IR), optical coherence tomography (OCT), and/or other imaging modalities that may be employed by a single imaging apparatus. Some aspects relate to improvements in white light, fluorescence, IR, OCT, and/or other imaging technologies that may be employed alone or in combination with other techniques. Some aspects relate to multi-modal imaging techniques that enable determination of a subject's health status.

Abstract: A medical system and method are disclosed herein. The medical system, in an embodiment, has computer-readable instructions configured to be executed by one or more processors to cause at least one display device of a wearable device to generate a plurality of graphics. The graphics are configured to stimulate a voluntary eye function of at least one eye of a subject, to stimulate an involuntary eye function of the at least one eye, and to block a vision of the at least one eye. The instructions are also configured to cause at least one sensor of the wearable device to sense eye movement, head movement, and pupillary resizing. The instructions are also configured to cause processing of a plurality of sensed eye parameters and any sensed head movement parameters and to generate an examination output that at least indicates a plurality of the sensed eye parameters.

Abstract: Aspects of the present disclosure provide improved techniques for imaging a subject's retina fundus. Some aspects relate to an imaging apparatus that may be substantially binocular shaped and/or may house multiple imaging devices configured to provide multiple corresponding modes of imaging the subject's retina fundus. Some aspects relate to techniques for imaging a subject's eye using white light, fluorescence, infrared (IR), optical coherence tomography (OCT), and/or other imaging modalities that may be employed by a single imaging apparatus. Some aspects relate to improvements in white light, fluorescence, IR, OCT, and/or other imaging technologies that may be employed alone or in combination with other techniques. Some aspects relate to multi-modal imaging techniques that enable determination of a subject's health status.

Abstract: Aspects of the present disclosure provide improved techniques for imaging a subject's retina fundus. Some aspects relate to an imaging apparatus that may be substantially binocular shaped and/or may house multiple imaging devices configured to provide multiple corresponding modes of imaging the subject's retina fundus. Some aspects relate to techniques for imaging a subject's eye using white light, fluorescence, infrared (IR), optical coherence tomography (OCT), and/or other imaging modalities that may be employed by a single imaging apparatus. Some aspects relate to improvements in white light, fluorescence, IR, OCT, and/or other imaging technologies that may be employed alone or in combination with other techniques. Some aspects relate to multi-modal imaging techniques that enable determination of a subject's health status.

Abstract: Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

Abstract: Remote monitoring device for body temperature in bovine and porcine cattle comprised by a fusiform temperature-conductor shell, a circular lid which hermetically closes the device, both coated with a biocompatible material, and an internal unit consisting on a thermic probe assembled to a programmable circuit, which provides data on the unique identification of the animal, which also consists on a radio transmitter, an aerial and the battery feeding the device. The device can be programmed to take the temperature readings, record and send the information to a receptor, which can transmit the data to any remote device through the 2G network.

Abstract: A system for analyzing brain tissue components based on magnetic resonance image. The system includes a memory and a processor. The memory stores instructions. The processor accesses and executes the instructions to perform the following: extracting maps of tissue from a brain magnetic resonance imaging (MRI) corresponding to normal subjects; averaging the maps of tissue according to a number of the normal subjects to generate reference maps that correspond to different tissues; receiving a brain MRI sample having a targeted region; and analyzing the brain MRI sample based on the reference maps and the targeted region to generate an analysis result, in which the analysis result indicates a ratio of tissues in the targeted region of the brain MRI sample.

Abstract: A system SY for determining a position of an OCT or IVUS catheter CA in a vasculature VA. The system SY includes a map-providing unit MPU, a data-providing unit DPU, and a comparator unit COMP. The map-providing unit is configured to provide a reference map SOM including reference measurement data at each of a plurality of positions P1 . . . k of the OCT or IVUS catheter CA in the vasculature VA. The data-providing unit DPU is configured to provide actual measurement data from an actual position in the vasculature VA. The comparator unit COMP is configured to determine from the plurality of positions P1 . . . k of the OCT or IVUS catheter in the vasculature, a position Pn?1 . . . k that corresponds to the actual position in the vasculature, based on a comparison of the actual measurement data and the reference measurement data. The reference measurement data and the actual measurement data are either i) OCT data or ii) IVUS data.

Abstract: Systems, methods, and devices for fluorescence imaging with a minimal area image sensor are disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation, wherein the pixel array comprises active pixels and optical black pixels. The system includes a black clamp circuit providing offset control for data generated by the pixel array. The system includes a controller comprising a processor in electrical communication with the image sensor and the emitter.

Abstract: Fluorescence imaging with reduced fixed pattern noise is disclosed. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation resulting from the plurality of pulses of electromagnetic radiation with a pixel array of an image sensor to generate a plurality of exposure frames. The method includes applying edge enhancement to edges within an exposure frame of the plurality of exposure frames. The method is such that at least a portion of the plurality of pulses of electromagnetic radiation emitted by the emitter comprises one or more of electromagnetic radiation having a wavelength from about 770 nm to about 790 nm; or from about 795 nm to about 815 nm.

Abstract: Fluorescence imaging with reduced fixed pattern noise is disclosed. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation resulting from the plurality of pulses of electromagnetic radiation with a pixel array of an image sensor to generate a plurality of exposure frames. The method includes applying edge enhancement to edges within an exposure frame of the plurality of exposure frames. The method is such that at least a portion of the plurality of pulses of electromagnetic radiation emitted by the emitter comprises one or more of electromagnetic radiation having a wavelength from about 795 nm to about 815 nm.

Abstract: Hyperspectral, fluorescence, and laser mapping imaging with reduced fixed pattern noise are disclosed. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation resulting from the plurality of pulses of electromagnetic radiation with a pixel array of an image sensor to generate a plurality of exposure frames. The method includes applying edge enhancement to edges within an exposure frame of the plurality of exposure frames. The method is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises one or more of: electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, from about 565 nm to about 585 nm, from about 900 nm to about 1000 nm, an excitation wavelength of electromagnetic radiation that causes a reagent to fluoresce, or a laser mapping pattern.

Abstract: Driving an emitter to emit pulses of electromagnetic radiation according to a jitter specification in a fluorescence imaging system is described. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a driver for driving emissions by the emitter according to a jitter specification. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises electromagnetic radiation having a wavelength from about 770 nm to about 795 nm and/or from about 795 nm to about 815 nm.

Abstract: Hyperspectral imaging with reduced fixed pattern noise is disclosed. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation resulting from the plurality of pulses of electromagnetic radiation with a pixel array of an image sensor to generate a plurality of exposure frames. The method includes applying edge enhancement to edges within an exposure frame of the plurality of exposure frames. The method is such that at least a portion of the plurality of pulses of electromagnetic radiation emitted by the emitter comprises one or more of electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, from about 565 nm to about 585 nm, or from about 900 nm to about 1000 nm.

Abstract: According to an embodiment of the disclosure, there is provided an electronic device including: an optical element that is fixed and is configured to split incident light reflected from an object into two or more incident light beams traveling along two or more light paths; an optical sensor that is spaced a separation distance from the optical element such that the split incident light beams form an interference area on a light receiving surface and is configured to detect the incident light; and at least one processor configured to determine state information about the object based on similarity between a first spectrum acquired from the detected incident light and at least one reference spectrum.

Abstract: Systems, methods, and devices for fluorescence imaging in a light deficient environment are disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a controller comprising a processor in electrical communication with the image sensor and the emitter. The system is such that the controller synchronizes timing of the pulses of electromagnetic radiation during a blanking period of the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises electromagnetic radiation having a wavelength from about 770 nm to about 790 nm.

Abstract: Offset illumination using multiple emitters in a hyperspectral imaging system is described. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The emitter comprises a first emitter and a second emitter for emitting different wavelengths of electromagnetic radiation. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, from about 565 nm to about 585 nm, and/or from about 900 nm to about 1000 nm.

Abstract: In an implementation, a processing device receives first intraoral scan data generated at a first time and analyzes the first intraoral scan data to determine a first representation of a caries from the first intraoral scan data. The processing device receives second intraoral scan data generated at a second time and analyzes the second intraoral scan data to determine a second representation of the caries from the second intraoral scan data. The processing device compares the second representation of the caries to the first representation of the caries and tracks the caries over time based on a difference between the second representation of the caries and the first representation of the caries.

Abstract: A method for calibrating a thermometer unit for measuring a core temperature of a system, includes determining a first heat transfer coefficient of the system, and calculating core temperature data corresponding to the core temperature of the system based on the first heat transfer coefficient. The method also includes identifying a change in the core temperature data that exceeds a predetermined threshold. The thermometer unit is calibrated by determining a second heat transfer in response to the identified change in the core temperature data. The core temperature data is calculated based on the second heat transfer coefficient.

Abstract: Described herein are embodiments of systems and methods that utilize temperature measurements taken with head-mounted sensors as well as images of a user's face to detect fever and/or intoxication. One embodiment of a system to detect fever includes a first head-mounted temperature sensor that measures skin temperature (Tskin) at a first region on a user's head, a second head-mounted temperature sensor that measures a temperature of the environment (Tenv), and a computer. The computer receives images of a second region on the user's face, captured by a camera sensitive to wavelengths below 1050 nanometer, and calculates, based on the images, values indicative of hemoglobin concentrations at three or more regions on the user's face. The computer can then detect whether the user has a fever based on Tskin, Tenv and the values.

Abstract: Methods and apparatuses for heart rate detection are described. In one example, a headphones apparatus and method includes emitting a first light in a first light direction directed at a left ear location from a left ear light emitter, and detecting a detected first light at a left ear light detector following interaction of the first light with a left ear tissue. The method includes emitting a second light in a second light direction directed at a right ear location from a right ear light emitter, the right ear location different from the left ear location. The method further includes detecting a detected second light at a right ear light detector following interaction of the second light with a right ear tissue, and estimating a heart rate from the detected first light and the detected second light.

Abstract: This disclosure is directed to devices, systems, and techniques for identifying a respiration rate based on an impedance signal. In some examples, a medical device system includes a medical device including a plurality of electrodes. The medical device is configured to perform, using the plurality of electrodes, an impedance measurement to collect a set of impedance values, where the set of impedance values is indicative of a respiration pattern of a patient. Additionally, the medical device system includes processing circuitry configured to identify a set of positive zero crossings based on the set of impedance values, identify a set of negative zero crossings based on the set of impedance values, and determine, for the impedance measurement, a value of a respiration metric using both the set of negative zero crossings and the set of positive zero crossings.

Abstract: An apparatus for calibrating a bio-information estimation model is provided. The apparatus may include a sensor configured to detect a bio-signal from an object of interest, and a processor configured to extract a first feature at each of a plurality of points of the bio-signal, extract a second feature at each of the plurality of points of the bio-signal, and determine a calibration point of the bio-information estimation model, from among the plurality of points of the bio-signal, based on a first degree of change in the first feature at each point relative to a first feature at a reference point and a second degree of change in the second feature at each point relative to a second feature at the reference point.

Abstract: Techniques and apparatuses are described that implement a smart-device-based radar system capable of detecting human vital signs in the presence of body motion. In particular, a radar system includes a body-motion filter module that employs machine learning to filter body motion from a received radar signal and construct a filtered signal that includes information regarding a user's vital signs. With machine learning, the radar system can filter the body motion without relying on data from other sensors to determine the body motion. Furthermore, the body-motion filter module can be trained to compensate for a variety of different types of body motions, such as those that occur while a user sleeps, exercises, drives, works, or is treated by a medical professional. By filtering the body motion, the radar system can accurately determine the user's vital signs and provide non-contact human vital-sign detection.

Abstract: An electronic device according to various embodiments may comprise: a housing; a display exposed through a first portion of the housing; a photoplethysmogram (PPG) sensor exposed through a second portion of the housing; a processor located within the housing and operatively connected to the display and the PPG sensor; and a memory located within the housing and operatively connected to the processor, wherein the memory is configured, when running, to: in a first operation, receive first data by using the PPG sensor, determine a plurality of reference ranges of blood pressure on the basis at least in part of the first data, and store the plurality of reference ranges, and in a second operation, receive second data by using the PPG sensor after the first operation, select at least one reference range among the plurality of reference ranges on the basis at least in part of the second data, and store instructions to induce the processor to provide at least one from among graphical user interface (GUI), text, a nu

Abstract: The invention comprises a system and method for identification and/or characterization of lesions and/or the various type of tissues inside blood vessels, including utilizing a laser system configured to transmit laser radiation towards and/or onto a lesion within a blood vessel, monitoring ablation of the lesion utilizing at least one acoustic sensor; and, using a processor, comparing the signals obtained from the acoustic signal to previously obtained acoustic signals associated with specific lesion types and determine a type of the lesion and/or an efficiency of the ablation process based on the comparison.

Abstract: Systems, methods, devices, and techniques for estimating an ejection-fraction characteristic of a mammal. An electrocardiogram (ECG) procedure is performed on a mammal, and a computer system obtains ECG data that describes results of the ECG over a period of time. The system provides a predictive input that is based on the ECG data to an ejection-fraction predictive model, such as a neural network or other machine-learning model. In response, the ejection-fraction predictive model processes the input to generate an estimated ejection-fraction characteristic of the mammal. The system outputs the estimated ejection-fraction characteristic of the mammal for presentation to a user.

Abstract: The invention relates to a cutaneous patch for monitoring the heart rate of an individual, as well as to a monitoring system comprising such a patch, and to an assembly that comprises a system of this type.

Abstract: A system for collecting and analyzing sweat includes a sweat sensing device having at least one sensor configured to sense one of physiologic information, biologic information, biochemical information, and biometric information, from skin of a person to whom the sweat sensing device is attached. A wireless transmitter is mounted to the sweat sensing device and electrically connected to the at least one sensor. An interactive console is configured to produce a real time feedback to an operator of the system for collecting and analyzing sweat, includes a wireless receiver, and is in wireless communication with the sweat sensing device. The interactive console is further configured to receive data from the at least one sensor, display the data received from the at least one sensor, adjust an environmental condition based on the sensor data received, and display the adjustment to the environmental condition.

Abstract: A biological information measuring device according to an aspect of the present disclosure includes: a light source that, in operation, emits irradiation light for irradiating a test portion of a subject; a light detector that, in operation, detects light from the subject and outputs an electrical signal corresponding to the light; and a control circuit that, in operation, determines a power of the irradiation light emitted by the light source, and that, in operation, measures biological information related to a blood flow at the test portion based on the electrical signal. The control circuit, in operation, detects a distance between the light source and the test portion based on the electrical signal, and determines the power of the irradiation light such that the power of the irradiation light is increased as the distance increases.

Abstract: Systems and methods for monitoring pulsatile flows are disclosed. One method includes obtaining a plurality of magnetic resonance imaging (MRI) scans of a biological structure, acquired consecutively in time, each of the MRI scans acquired using a modified True FISP sequence. The method also includes assembling the plurality of scans into a video file of the biological structure and identifying pulsatile features within the video file.

Abstract: A pulse transit time measuring apparatus according to one aspect includes a belt unit configured to be wrapped around a measurement site of a user, an electrocardiogram acquisition unit including electrodes provided at the belt unit and configured to acquire an electrocardiogram of the user by using the electrodes, a pulse wave signal acquisition unit including a pulse wave sensor provided at the belt unit, and configured to acquire a pulse wave signal representing a pulse wave of the user by using the pulse wave sensor, and a pulse transit time calculation unit configured to calculate a pulse transit time based on a time difference between a waveform characteristic point of the electrocardiogram and a waveform characteristic point of the pulse wave signal.

Abstract: A wearable apparatus and a method of adjusting the same, wherein the wearable apparatus comprises: a determining circuit configured to determine whether the wearable apparatus has been switched to a preset operating mode; an adjusting circuit configured to adjust the wearable apparatus to satisfy an operating requirement of a current operating mode when the determining circuit determines that the wearable apparatus has been switched to the preset operating mode.

Abstract: The invention relates to a passive pressure sensor (501) for being introduced into the circulatory system of a human being and for being wirelessly read out by an outside reading system. The pressure sensor comprises a casing (502) with a diffusion blocking layer for maintaining a predetermined pressure within the casing and a magneto-mechanical oscillator with a magnetic object (508) providing a permanent magnetic moment. The magneto-mechanical oscillator transduces an external magnetic or electromagnetic excitation field into a mechanical oscillation of the magnetic object, wherein at least a part of the casing is flexible for allowing to transduce external pressure changes into changes of the mechanical oscillation of the magnetic object. The pressure sensor can be very small and nevertheless provide high quality pressure sensing.

Abstract: A capacitive pressure sensor (10) is disclosed comprising a membrane (21) including a second electrode (23) spatially separated by a cavity (20) from a substrate (11) including a first electrode (13) opposing the second electrode; and a central pillar (22) extending from the membrane to the substrate such that the cavity is an annular cavity enveloping said central pillar. Also disclosed is an invasive medical instrument comprising such a capacitive pressure sensor and a method of manufacturing such a capacitive pressure sensor.

Abstract: The exemplified methods and systems facilitate one or more dynamical analyses that can characterize and identify nonlinear dynamical properties (such as Lyapunov exponent (LE), correlation dimension, entropy (K2), or statistical and/or geometric properties derived from Poincaré maps, etc.) of biophysical signals such as photoplethysmographic signals and/or cardiac signals to predict presence and/or localization of a disease or condition, or indicator of one, including, for example, but not limited to, coronary artery disease, heart failure (including but not limited to elevated or abnormal left ventricular end-diastolic pressure disease) and pulmonary hypertension, among others.

Abstract: An apparatus with a photodetector area comprising a first photodetector area and a second photodetector area, the first and second photodetector areas having co-planar interlocking shapes, and an optical blocking filter configured to filter light incident on the second photodetector area.

Abstract: The exemplified methods and systems facilitate one or more dynamical analyses that can characterize and identify synchronicity between acquired cardiac signals and photoplethysmographic signals to predict/estimate presence, non-presence, localization, and/or severity of abnormal cardiovascular conditions or disease, including, for example, but not limited to, coronary artery disease, heart failure (including but not limited to indicators of disease or conduction such as abnormal left ventricular end-diastolic pressure disease), and pulmonary hypertension, among others. In some embodiments, statistical properties of the synchronicity between cardiac signals and photoplethysmographic signals are evaluated. In some embodiments, statistical properties of histogram of synchronicity between cardiac signals and photoplethysmographic signals are evaluated.

Abstract: An intrathoracic pressure sensor includes: a first tube that is adapted to be inserted into a trachea of a patient to define a first gas passage configured to communicate with the trachea; a first cuff disposed in a portion of the first tube which is to be placed in the trachea, the first cuff being inflatable and deflatable; a second tube that defines a second gas passage configured to communicate with an interior of the first cuff; and a transducer configured to output a signal corresponding to a pressure in the second gas passage.

Abstract: The provided systems, methods and devices describe lightweight, wireless tissue monitoring devices that are capable of establishing conformal contact due to the flexibility or bendability of the device. The described systems and devices are useful, for example, for skin-mounted intraoperative monitoring of nerve-muscle activity. The present systems and methods are versatile and may be used for a variety of tissues (e.g. skin, organs, muscles, nerves, etc.) to measure a variety of different parameterps (e.g. electric signals, electric potentials, electromyography, movement, vibration, acoustic signals, response to various stimuli, etc.).

Abstract: Systems and methods for facilitating display of cardiac information based on sensed electrical signals include a processing unit configured to receive a set of electrical signals; receive an indication of a measurement location corresponding to each electrical signal of the set of electrical signals; and generate an activation histogram corresponding to the set of electrical signals. Systems and methods disclosed herein may be configured to automatically identify activation histograms exhibiting split characteristics, and to facilitate presentation, on a display device, of a cardiac map including highlighted regions corresponding to the identified activation histograms.

Abstract: A method includes receiving analog body-surface signal from body-surface electrode, and multiple analog unipolar signals from multiple unipolar electrodes of an invasive probe. A first unipolar electrode is assigned to serve as a common electrical ground and a common timing reference for the analog unipolar signals and the analog body-surface signal. The analog unipolar signals are digitized to produce digital unipolar signals sampled relative to a digital ground. Defined are an analog bipolar signal between the first unipolar electrode and a second unipolar electrode of the probe, and digital bipolar signal formed from the first unipolar electrode and the second unipolar electrode. Ground and timing offsets between the analog bipolar signal and the digital bipolar signal are estimated, while the first unipolar electrode is connected to the digital ground. The ground offset and the timing offset are applied in measuring a third unipolar signal, sensed by a third unipolar electrode.

Abstract: Systems and methods for measuring transmural activation times between an endocardial surface and an epicardial surface are provided. A system includes at least one catheter including at least one electrode, the at least one catheter configured to acquire electrogram data and positioning data proximate at least one of the endocardial surface and the epicardial surface. The system further includes a computing device communicatively coupled to the at least one catheter, the computing device configured to determine transmural activation times based on the acquired electrogram data and positioning data.

Abstract: A detection device generates plural attractors based on brainwave data. Subsequently, the detection device calculates a Betti number by subjecting the attractors to persistent homology transform. The detection device determines an onset of encephalopathy based on a first order component of a Betti sequence calculated based on the Betti number.

Abstract: A system for evaluating neurologic dysfunction of a subject includes an odorant generator configured to deliver an odorant stimulation to the subject, an auditory generator configured to deliver an audible stimulation to the subject, a vibrotactile stimulator configured to generate a somatosensory stimulation to the subject, a plurality of electrodes configured to be attached to the subject at respective different locations, and at least one processor. The plurality of electrodes are configured to collect neural signals from the subject as a result of the odorant stimulation, the audible stimulation, and the somatosensory stimulation. The at least one processor is configured to process the neural signals from the plurality of electrodes and generate an assessment of neurologic dysfunction of the subject.

Abstract: The present invention relates generally to method and device for the detection of drug levels in blood flow using the application of magnetic fields for the detection of small electronic currents. The method of the present invention includes the electromagnetic measurements that are based on the readings of the sensitivity of a giant magnetoresistance sensor which senses the magnetic field induced by the ions of the circulating drug in arterial blood flow. The device includes a pressure cuff, a magnetic sensor, a permanent magnet, data acquisition box, and a graphical user interface to control input data and read the current drug concentration in the arterial blood flow.

Abstract: A wearable monitoring apparatus for monitoring at least one biological parameter of an internal tissue of an ambulatory user. Said wearable monitoring apparatus comprises at least one transducer configured for delivering electromagnetic (EM) radiation to said internal tissue and intercepting a reflection of said EM radiation said reform in a plurality of transmission sessions during at least 24 hours, a processing unit configured for analyzing respective said reflection and identifying a change in said at least one biological parameter accordingly, a reporting unit configured for generating a report according to said change, and a housing for containing said at least one transducer, said reporting unit, and said processing unit, said housing being configured for being disposed on said body of said ambulatory user.

Abstract: Systems and methods for generating thin slice images from thick slice images are disclosed herein. In some examples, a deep learning system may calculate a residual from a thick slice image and add the residual to the thick slice image to generate a thin slice image. In some examples, the deep learning system includes a neural network. In some examples, the neural network may include one or more levels, where one or more of the levels include one or more blocks. In some examples, each level includes a convolution block and a non-linear activation function block. The levels of the neural network may be in a cascaded arrangement in some examples.

Abstract: A magnetic resonance imaging method includes: obtaining three-dimensional under-sampling data of a target object based on a first three-dimensional magnetic resonance imaging sequence; obtaining a three-dimensional point spread function based on the three-dimensional under-sampling data or a two-dimensional mapping data of the target object; obtaining a sensitivity map of the target object based on the data collected by three-dimensional low-resolution complete sampling; performing imaging reconstruction to the three-dimensional under-sampling data based on the three-dimensional point spread function and the sensitivity map to obtain a reconstructed magnetic resonance image. The first three-dimensional magnetic resonance imaging sequence has a first sinusoidal gradient field on a phase direction and a second sinusoidal gradient field on a layer selection direction. 0-order moments of the first and the second three-dimensional magnetic resonance imaging sequences are 0.