Abstract: The invention provides to PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma) gene fusions and PIK3C2G fusion proteins. The invention further provides methods of diagnosing and treating diseases or disorders associated with PK3C2G fusions, such as conditions mediated by aberrant PIK3C2G expression or activity, or conditions associated with overexpression of PIK.3C2G.

Abstract: The provided scaffolds have heavy chains that are asymmetric in the various domains (e.g. CH2 and CH3) to accomplish selectivity between the various Fc receptors involved in modulating effector function, beyond those achievable with a natural homodimeric (symmetric) Fc molecule, and increased stability and purity of the resulting variant Fc heterodimers. These novel molecules comprise complexes of heterogeneous components designed to alter the natural way antibodies behave and that find use in therapeutics.

Abstract: Provided is a cellulose acetate powder that makes it possible to reduce the formation of spotty patches on a formed article of the cellulose acetate and prevent lowering of the production process passability of the formed article. A cellulose acetate powder includes cellulose acetate having an acetylation degree of 53 to 56% and a 6% viscosity of 30 to 200 mPa·s. In the cellulose acetate powder, a cumulative pore volume is not less than 0.200 ml/g; a proportion of particles having a particle diameter of not less than 500 ?m is not higher than 40%; and an angle of repose is not greater than 51°.

Abstract: Hemostatic devices and methods of making same are disclosed. Disclosed hemostatic devices include biocompatible non-oxidized regenerated cellulose. The disclosed hemostatic devices are effective in providing and maintaining hemostasis in cases of moderate to severe bleeding caused by non-compressional and/or non-tourniquetable injuries, among other things. The disclosed methods enable manufacture of a bioabsorbable, biocompatible, biodegradable carboxymethyl cellulose having high stability and high adherence.

Abstract: The present invention relates to nanocrystalline cellulose, an efficient way of its preparation and to uses of such nanocrystalline cellulose. The present invention also relates to porous metal oxides having a chiral nematic structure which are prepared using nanocrystalline cellulose.

Abstract: Disclosed are methods relating to an extruded pregelatinized, partially hydrolyzed starch prepared by mixing at least water, non-pregelatinized starch, and acid to form a starch precursor. The acid can be a weak acid that substantially avoids chelating calcium ions or a strong acid in a small amount. In the method, pregelatinization and acid-modification of the starch precursor occurs in one step in an extruder. Also disclosed are methods of preparing board using the starch prepared according to the methods, as well as starches and boards prepared by various methods of the invention.

Abstract: The invention relates to N-desulfated and optionally 2-O-desulfated glycosaminoglycan derivatives, wherein at least part of the adjacent diols and OH/NH2 have been converted into the corresponding aldehyde, which aldehydes have been then reduced to the corresponding alcohol. These products are endowed with heparanase inhibitory activity and anti-tumor activity. Said glycosaminoglycan derivatives are obtained from natural or synthetic glycosaminoglycan, preferably from unfractionated heparin, low molecular weight heparins (LMWHs), heparan sulfate or derivatives thereof. The invention further relates to the process for preparation of the same and further to their use as active ingredients of medicaments, also in combination with known established drugs or treatments. The present invention further relates to a process for breaking the C2-C3 linkage of glucosamine residues of a glycosaminoglycan by oxidation of said glycosaminoglycan.

Abstract: An object of the present disclosure is to provide a terminal-modified conjugated dime polymer capable of improving fracture resistance of a rubber article. Specifically, a terminal-modified conjugated diene polymer is characterized in that a content of catalyst residue therein derived from a catalyst used in polymerization is less than 60 ppm.

Abstract: This invention is to improve the reaction efficiency of a peroxide introduced into a cylinder compared with conventional art. In the peroxide reaction method and peroxide reaction device using an extruder according to this invention, in which a peroxide and a raw material such as a synthetic resin, a natural resin, and an elastomer are introduced into a cylinder of the extruder, wherein the raw material and the peroxide are reacted with each other in the cylinder, the raw material is introduced from a raw material supply hopper, the peroxide is introduced from a downstream side of the raw material supply hopper, and the temperature of the raw material in a peroxide introduction portion is adjusted to a temperature lower than the one-minute half-life temperature of the peroxide.

Abstract: A method produces a polymer composition with improved DC electrical properties. A cable can be surrounded by at least one layer that includes the polymer composition. The polymer composition includes a polyolefin, and the polymer composition has an electric conductivity of 0.50×10?15 S/m or less, when measured according to DC conductivity method using a tape sample consisting of the polymer composition.

Abstract: To provide a fluorinated polymer which can be heat-cured at low temperature (from room temperature to 150° C.). A fluorinated polymer containing units represented by the following formula (1): wherein X1 and X2 are each independently a hydrogen atom or a fluorine atom, Q1 is a single bond or an etheric oxygen atom, Rf1 is a fluoroalkylene group or a fluoroalkylene group having at least 2 carbon atoms and having an etheric oxygen atom between carbon atoms, Z1 is NR1—Y1, O—Y2 or S—Y3, R1 is a hydrogen atom, an alkyl group or an aryl group, and Y1, Y2 and Y3 are each independently a group having at least one hydrolyzable silyl group.

Abstract: Polyvinyl acetals with a degree of acetalization of 70-84 mol %, and characterized by a molar ratio of the amount of continuous syndiotactic sequences of vinyl alcohol groups with 3 members of at least 0.152, based on the total amount of vinyl alcohol groups in the polyvinyl acetal, have exceptionally low melt flow.

Abstract: A polymeric foam precursor composition including the following components: (a) a di- or tri-functional (meth)acrylate oligomer (2); (b) a di- or higher-functional thiol compound (3); and (c) a borane compound (4) as initiator. The foam precursor composition can be isocyanate free, and the curing rate is largely moisture independent and can cure at low temperatures, below freezing point.

Abstract: Polar silane linkers are provided that attach to resins to form silane-functionalized resins. The functionalized resins can be bound to hydroxyl groups on the surface of silica particles to improve the dispersibility of the silica particles in rubber mixtures. Further disclosed are synthetic routes to provide the silane-functionalized resins, as well as various uses and end products that benefit from the unexpected properties of the silane-functionalized resins. Silane-functionalized resins impart remarkable properties on various rubber compositions, such as tires, belts, hoses, brakes, and the like. Automobile tires incorporating the silane-functionalized resins are shown to possess excellent results in balancing the properties of rolling resistance, tire wear, and wet braking performance.

Abstract: A process for producing aqueous solutions of acrylic acid polymers by polymerization of acrylic acid in feed operation with a free-radical starter in the presence of hypophosphite in water as solvent, which comprises (i) initially charging water and optionally acrylic acid in acidic, unneutralized form, optionally one or more ethylenicaliy unsaturated comonomers, optionally aqueous hypophosphite solution and optionally initiator, (ii) adding acrylic acid in acidic, unneutralized form, optionally one or more ethylenicaliy unsaturated comonomers, aqueous free-radical starter solution and aqueous hypophosphite solution, (iii) adding a base to the aqueous solution after termination of the acrylic acid feed, wherein the comonomer content does not exceed 30 wt % based on the total monomer content, wherein the acrylic acid, the aqueous free-radical starter solution and the aqueous hypophosphite solution are added such that the molar ratio x of acrylic acid to phosphorus-bound hydrogen [AA]/[P—H] over a time period

Abstract: A propylene, ethylene, 1-butene terpolymer made from or containing a) from about 1.8 wt % to about 5.9 wt % of ethylene derived units; and b) from about 2.0 wt % to about 4.5 wt % of 1 butene derived units; and having i) a ratio of C2 wt %/C4 wt % in the range from about 0.9 to about 1.3; wherein C2 wt % is the weight percent of ethylene derived units and C4 wt % is the weight percent of 1-butene derived units; ii) a Melt flow rate (determined according to ISO 1133 230° C., 2.16 kg) in the range from about 1.0 to about 30.0 g/10 min; and iii) a xylene soluble fraction at 25° C. between about 10 wt % and about 30 wt %. The weight percentages are based upon the total weight of the terpolymer.

Abstract: Provided herein are polyolefin dispersants, as well as methods for producing polyolefin dispersants. The polyolefin dispersants can be defined by the formula below where Rx is cationic initiator residue; Ra is a polyolefin group; R1 and R2 are each, independently in each —(CR1R2) unit, H, alkyl, alkoxy, or alkylaryl; R3 and R4 are each, independently, H, alkyl, or alkoxy; m is an integer from 1 to 20; n is an integer from 1 to 6; r is an integer from 1 to 4; Y is a polyvalent amine linker comprising one or more tertiary amines, wherein the polyvalent amine linker does not include a primary amine or a secondary amine; and A is absent, or comprises a dispersive moiety.

Abstract: New ethylene polymers having low levels of long chain branching are disclosed. Films and film layers made form these polymers have good hot tack strength over a wide range of temperatures, making them good materials for packaging applications.

Abstract: Curable fluoropolymer containing repeating units derived from VDF and TFE and at least one other fluorinated comonomer and further containing —CF2CH2I end groups and branching sites derived from one or more perfluorinated bisolefinic ether(s) used as modifier(s), wherein the one or more perfluorinated bisolefinic ether(s) used as modifier(s) correspond to the general formula: CF2?CF—(CF2)n—O—(R1)—O—(CF2)mCF?CF2 wherein n and m are independent from each other either 1 or 0 and wherein R1 represents a perfluorinated linear or branched, cyclic or acyclic aliphatic or aromatic hydrocarbon residue that may be interrupted by one or more oxygen atoms and comprises up to 30 carbon atoms. Further provided are methods of making the curable fluoropolymers and for making an article containing the curable polymers.

Abstract: The present invention relates to polymerizable and photochemically crosslinkable compositions which contain at least one polymerizable benzaldehyde derivative according to general formula I and which are suitable as materials for technical and medical applications, for example in surgery or ophthalmology, and in particular as dental materials.

Abstract: Provided are a coloring composition having excellent heat resistance and solvent resistance, a cured film, a color filter, a method for manufacturing a color filter, a solid-state imaging device, an image display device, and a polymer. The coloring composition includes a polymer TP consisting only of a repeating unit A having a triarylmethane structure and a repeating unit B having an acid group, and a polymerizable compound, in which the polymer TP contain the repeating unit B in the amount of 12% to 60% by mass with respect to all the repeating units of the polymer TP.

Abstract: Disclosed is a propylene-diene copolymer resin having excellent melt tension, with improved melt strength, high molecular weight and broad molecular weight distribution by using a specific metallocene catalyst system. The present invention provides a propylene-diene copolymer resin produced by polymerizing propylene and a diene compound of C4-C20 by using a metallocene catalyst system, wherein the propylene-diene copolymer resin has the melt index (2.16 kg load at 230° C.) of 0.1-100 g/10 min and the melt tension (advanced rheometric expansion system (ARES)) of 5-100 g.

Abstract: An object of the present invention is to provide a multicomponent copolymer for use for producing a rubber composition and a rubber product having high abrasion resistance and wet performance. Further, the invention is to provide a rubber composition containing the multicomponent copolymer, a crosslinked rubber composition produced by crosslinking the rubber composition, and a tire and a rubber product using the rubber composition or the crosslinked rubber composition. The multicomponent copolymer of the invention contains a conjugated diene unit, a non-conjugated olefin unit and an aromatic vinyl unit, wherein the content of the aromatic vinyl unit is 5 mol % or more and less than 50 mol % of the whole multicomponent copolymer and the content of the non-conjugated olefin unit is more than 0 mol % and 50 mol % or less of the whole multicomponent copolymer.

Abstract: This invention relates to an alkoxylated calixarene resin comprising one or more modified calixarene alkoxylate compounds. The invention also relates to a process for preparing a solubilized alkoxylated calixarene resin comprising reacting a phenolic resin mixture, comprising linear phenolic resins and calixarene compounds having phenolic hydroxyl groups, with one or more epoxide-containing compounds to alkoxylate one or more of the phenolic hydroxyl groups of the calixarene compounds to form a solubilized phenolic resin mixture, and reacting the solubilized phenolic resin mixture with one or more alkylene oxides.

Abstract: The invention relates to a method for synthesizing NCO-terminated polyurethanes having improved elastic properties, said method involving the staggered addition of diisocyanate(s). The invention also relates to NCO-terminated polyurethanes that have high elongation at break and can be obtained using the disclosed method. The invention finally relates to adhesive, mastic and/or coating compositions comprising the disclosed NCO-terminated polyurethane.

Abstract: In various embodiments, the present invention is directed to new low cost initiator compositions for use with the production of well-defined telechelic PIBs (by LC+P of isobutylene). In various other embodiments, the present invention is directed to methods for using these novel compositions as initiators for isobutylene (IB) and other cationically polymerizable monomers, such as styrene and its derivatives. In still other embodiments, the present invention is directed to structurally new, allyl (and chlorine) telechelic PIBs formed from these new initiator compositions and their derivatives (in particular, hydroxyl telechelic PIB and amine telechelic PIB). In yet other embodiments, the present invention is directed to structurally new polyurethanes, polyureas, and polyurethane ureas made using telechelic PIBs formed from these new initiator compositions.

Abstract: An isocyanate prepolymer composition and a crosslinked thermoplastic polyurethane composition are disclosed, preferably in the form of a fiber. Also disclosed is the process for preparing said prepolymer composition and crosslinked thermoplastic polyurethane. Both of the isocyanate prepolymer composition and crosslinked thermoplastic polyurethane show improved properties.

Abstract: Four conjugated copolymers with a donor/acceptor architecture including 4,4-dihexadecyl-4H-cyclopenta[1,2-b:5,4-b?]dithiophene as the donor structural unit and benzo[2,1,3]thiodiazole fragments with varying degrees of fluorination have been synthesized and characterized. It has been shown that the HOMO levels were decreased after the fluorine substitution. The field-effect charge carrier mobility was similar for all polymers with less than an order of magnitude difference between different acceptor units.

Abstract: A method for synthesizing a polybutylene adipate terephthalate-polylactic acid (PBAT-PLA) copolyester, the method including: uniformly blending a first prepolymer PBAT and a second prepolymer PLA to yield a mixture, 0putting the mixture in a vacuum reactor with a vacuum degree of between 5 and 100 pascal, heating the vacuum reactor to a temperature of between 100 and 110° C., and allowing to react for between 0.5 and 1 hr; stepwise increasing the temperature to be between 145 and 155° C. in between 1 and 2 hrs, and allowing to react for between 5 and 10 hrs, to yield a PBAT-PLA copolyester with a weight-average molecular weight of between 100000 and 250000. The method for synthesizing the PBAT-PLA copolyester is eco-friendly, non-toxic and cost-efficient.

Abstract: Polymers and methods of making the same are described whereby the polymers generically include one or more units each of which necessarily has a 1,2,4-substituted cyclohexane group or a 1,1,2,4-substituted cyclohexane group. According to specific disclosures herein, polymers and methods of making the same are described whereby the polymers have one or more S1 units represented by the formula: wherein n is an integer equal to or higher than 1, m is 0 or 1, A is H or CH3, and wherein each of X and Y is a specifically defined group.

Abstract: A silane-modified polyester blend comprising a polyester polymer homogeneously blended with silane molecules containing two or three alkoxy groups bound to the silicon atom, wherein said silane molecules are present in said polyester blend in an amount of 0.05-20 wt % (or, e.g., 0.05-10 wt %, 0.05-5 wt %, or 0.05-2 wt %). The polyester polymer may, in particular embodiments, be a polyhydroxyalkanoate, terephthalate-based polyester, adipate-based, or succinate-based polyester. The silane molecule may be according to the formula (R2O)2SiR3R4, wherein R2 groups are independently selected from alkyl groups containing 1-4 carbon atoms; and R3 and R4 are independently selected from OR2 groups and alkyl groups containing 1-12 carbon atoms, provided that at least one of R3 and R4 is an alkyl group, wherein the alkyl group optionally includes one or more heteroatoms selected from oxygen, nitrogen, halogen, sulfur, phosphorus, and silicon. Methods for producing the silane-modified polyester blend are also described.

Abstract: A polycarbonate diol is provided, including three kinds of repeating diol units, wherein one of the repeating diol units is chosen from an alkoxylated diol monomer.

Abstract: A method of making a polyamide copolymer includes subjecting a reaction mixture to conditions sufficient to form the polyamide copolymer, the reaction mixture including adduct A and adduct B. Adduct A is a 1:1 adduct of a diamine having the structure H2N-R1-NH2, or a salt thereof and an aliphatic diacid having the structure HO—C(O)—R2-C(O)—OH, or a salt thereof. Adduct B is a 1:1 adduct of the diamine having the structure H2N-R1-NH2, or a salt thereof, and an aromatic diacid having the structure HO—C(O)—R3-C(O)—OH, or a salt thereof. At each occurrence, R1 and R2 can be independently a substituted or unsubstituted (C1-C20)alkylene. At each occurrence, R3 can be independently a substituted or unsubstituted (C6-C20)arylene. The molar ratio of adduct A to adduct B in the reaction mixture can be about 61:39 to about 90:10.

Abstract: Powder compositions for laser sintering. Nylon copolymer compositions are described which provide enhanced performance in processing and finished products when used in 3D laser sintering processes.

Abstract: A polymer compound to be used as a binder for a negative electrode of a power storage device is provided. The polymer compound is formed by condensation of a polyacrylic acid and a polyfunctional amine represented by the following general formula (1), where X is a ring structure having 1 to 3 benzene rings; and C1 to C4 are each a carbon atom constituting a benzene ring in the ring structure.

Abstract: This disclosure relates to dielectric film forming compositions containing a) at least one fully imidized polyimide polymer; b) at least one metal-containing (meth)acrylates; c) at least one catalyst; and d) at least one solvent, as well as related processes and related products. The compositions can form a dielectric film that generates substantially no debris when the dielectric film is patterned by laser ablation process.

Abstract: The present invention relates to a polyarylene sulfide having more improved miscibility with other polymer materials or fillers, and a method of preparing the same. At least part of end groups of the main chain of the polyarylene sulfide is carboxyl group (—COOH) or amine group (—NH2).

Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.

Abstract: A new class of cyclotrisiloxanes having hydridosiloxanylalkyl substituents on one, two, or three of the ring silicon atoms and a method for their preparation are provided. These compounds undergo living anionic ring-opening polymerization to generate unique polymer structures.

Abstract: [Problem] To provide a composition for forming a coating layer having excellent gas barrier performance and a method of forming the coating layer. [Means for Solution] A composition for forming a coating film comprising a specific silicon compound which reacts with a polysilazane by exposure, a polysilazane and an organic solvent, and a method for forming a coating layer comprising coating the composition on a substrate and exposing.

Abstract: The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. Glyme chain length and water content strongly influence the mechanical, electronic, and optical behavior of the network.

Abstract: This invention describes the manufacture of partially cured binder compositions based upon modification of drying oils with at least one multi-functional co-vulcanizing agent. The partially cured binder compositions can be used to produce products such as cured solid layers. These layers can be used in flooring materials, coatings, printing inks, and paints. Methods of manufacturing the partially cured binder compositions and cured solid layers are described.

Abstract: A process for producing superabsorbents, comprising polymerization, drying, crushing, pneumatic conveying, comminuting and classifying, wherein the gas temperature at the end of the pneumatic conveying is from 50 to 95° C.

Abstract: The present invention provides an ionic liquid represented by the following chemical formula (I): [(CH3)3N(CH2)2OH]+[NH2-L-COO]???(I) where L is —(CH2)2— or —(CH2)3—. The present invention also provides an ionic liquid composition containing an ionic liquid; and water. The ionic liquid is represented by the above chemical formula (I). A molar ratio of [(CH3)3N(CH2)2OH]+ to [NH2-L-COO]? is not less than 0.86 and not more than 1.12. A weight ratio of the water to the ionic liquid composition is not more than 4.7%. The present invention provides an ionic liquid capable of dissolving cellulose without an cellulose-degrading enzyme (namely, an enzyme capable of hydrolyzing cellulose).

Abstract: Methods for producing 3D printing composite polymer materials for use in additive manufacturing processes are provided. The methods result in enhancing the material properties of the printing material by providing a uniform and smooth surface finish of the printing material and the nozzle extrudate for additive manufacturing processes, such as Fused Filament Fabrication. The method includes implementing impregnation techniques for combining carbon nanotubes or other nano-fillers, a polymer resin and a fiber material to produce a polymer material that can be processed into a printing material. Further, the method may include combining the carbon nanotubes or other nano-fillers and the polymer resin to form a masterbatch that may be further combined with the fiber material through an extrusion process. The method results in a printing material with enhanced material properties and smooth surface finish for the printing material and resulting nozzle extrudate for Fused Filament Fabrication.

Abstract: Methods for producing 3D printing composite polymer materials for use in additive manufacturing processes are provided. The methods result in enhancing the material properties of the printing material by providing a uniform and smooth surface finish of the printing material and the nozzle extrudate for additive manufacturing processes, such as Fused Filament Fabrication. The method includes implementing impregnation techniques for combining carbon nanotubes or other nano-fillers, a polymer resin and a fiber material to produce a polymer material that can be processed into a printing material. Further, the method may include combining the carbon nanotubes or other nano-fillers and the polymer resin to form a masterbatch that may be further combined with the fiber material through an extrusion process. The method results in a printing material with enhanced material properties and smooth surface finish for the printing material and resulting nozzle extrudate for Fused Filament Fabrication.

Abstract: The present invention provides a heat-curable resin composition, which comprises (1) a heat-curable resin mixture comprising a heat-curable resin (a) and thickener particles (b) and exhibiting a viscosity (150° C.) after having been held at a temperature of 150° C. for 30 seconds that is a viscosity (S), and (2) a curing agent, and is characterized in that the heat-curable resin composition exhibits a lowest viscosity (R) at 80-120° C., the lowest viscosity (R) is 0.1-10 Pa·s, and the viscosity (S) and lowest viscosity (R) satisfy the relationship of formula (1): 5<S/R<200??formula (1).

Abstract: An anti-fogging and anti-fouling laminate, including: a substrate; and an anti-fogging and anti-fouling layer on the substrate where a surface of the anti-fogging and anti-fouling layer is flat, wherein the anti-fogging and anti-fouling layer is a cured product obtained by curing an active energy ray curable resin composition through an active energy ray, wherein the active energy ray curable resin composition includes a hydrophilic monomer having a radically polymerizable unsaturated group and a photopolymerization initiator, wherein a content of the hydrophilic monomer having a radically polymerizable unsaturated group in the active energy ray curable resin composition is 60% by mass or more, and wherein a surface of the anti-fogging and anti-fouling layer has a pure water contact angle of 90° or more.

Abstract: The present disclosure provides composites comprising an open cell foam and a small pore area material, methods for their preparation, articles of manufacture comprising them and methods for preparing the same.

Abstract: A foaming process for converting fibrous material into a cellular foam structure includes mixing fibrous material and a solvent-based binding agent to form a mixture; saturating the mixture with a pressurized gas to form a gas-saturated mixture; expanding the gas-saturated mixture by reducing the pressure of the pressurized gas to form an expanded mixture with voids in the fibrous material; and curing the expanded mixture to set the fibrous material and drive off the solvent to provide a stable network of fibrous material having cushioning properties.