Patents Issued in December 31, 2020
  • Publication number: 20200407277
    Abstract: A cementitious composition of one embodiment, according to the present teaching, includes, but is not limited to, a Portland cement, and at least one other cement from a group comprising, but not limited to, calcium sulfoaluminate cement, a calcium aluminosilicate cement, and calcium aluminate, wherein the Portland cement has a content of at least 20 percent based on the total weight of the non-Portland hydratable cement powder, wherein the cementitious composition bonds to asphalt.
    Type: Application
    Filed: March 4, 2020
    Publication date: December 31, 2020
    Inventor: Paul Sampson
  • Publication number: 20200407278
    Abstract: A ceramic membrane is provided, which may include glass, incinerator fly ash, kaolin and palygorskite. The weight percent of the glass may be 30˜60 wt %. The weight percent of the incinerator fly ash may be 5˜30 wt %. The weight percent of the kaolin may be 0˜50 wt %. The weight percent of the palygorskite is 0˜30 wt %.
    Type: Application
    Filed: June 18, 2020
    Publication date: December 31, 2020
    Inventors: Sue-Huai Gau, Chang-Jung Sun, Ming-Guo Li, Cheng-Gang Chen, Ching-Chieh Yang, Shau-Jiun Wu
  • Publication number: 20200407279
    Abstract: The composite sintered body includes Al2O3, and MgAl2O4. The content of Al2O3 in the composite sintered body is not less than 95.5% by weight. The average sintered grain size of Al2O3 in the composite sintered body is not less than 2 ?m and not greater than 4 ?m. The standard deviation of sintered grain size distribution of Al2O3 in the composite sintered body is not greater than 0.35. The bulk density of the composite sintered body is not less than 3.94 g/cm3 and not greater than 3.98 g/cm3. In the composite sintered body, the ratio of amount of crystal phase of MgAl2O4 to that of Al2O3 is not less than 0.003 and not greater than 0.01.
    Type: Application
    Filed: September 16, 2020
    Publication date: December 31, 2020
    Applicant: NGK INSULATORS, LTD.
    Inventors: Kyohei ATSUJI, Noboru NISHIMURA, Asumi NAGAI, Yuji KATSUDA
  • Publication number: 20200407280
    Abstract: A sintered rare earth oxyfluoride compact is composed of LnaObFc (wherein Ln is a rare earth element; and a, b, and c each independently represent a positive number, provided that they are not equal to each other) or Ca-stabilized LnOF as a primary phase and LnOF unstabilized with Ca as a secondary phase. The intensity ratio of the XRD peak of the (018) or (110) plane of the unstabilized LnOF to the highest XRD peak of LnaObFc is preferably 0.5% to 30%.
    Type: Application
    Filed: September 8, 2020
    Publication date: December 31, 2020
    Inventors: Hitoshi KAJINO, Shoji IMAURA
  • Publication number: 20200407281
    Abstract: The disclosure provides an MAX phase material, a preparation method therefor, and application thereof. The molecular formula of the MAX phase material is represented as Mn+1(AzA?1?z)hXn, wherein M is selected from group IIIB, IVB, VB or VIB elements, A is selected from element Zn, Cu, Ni, Co, Fe or Mn, A? is selected from group IB, IIB, VIII, IVA, VA or VIA elements, X is selected from elements C and/or N, n is 1, 2, 3 or 4, 0<z?1, a unit cell of the MAX phase material is formed by alternately stacking Mn+1Xn units and (AzAzA?1?z)h layers of atoms, and h is the number of layers of the (AzAzA?1?z) layers of atoms located between the Mn+1Xn unit layers, and h is 1, 2 or 3.
    Type: Application
    Filed: November 28, 2018
    Publication date: December 31, 2020
    Applicant: NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Qing HUANG, Mian LI, Youbing LI, Xiaobing ZHOU, Kan LUO, Shiyu DU, Zhengren HUANG
  • Publication number: 20200407282
    Abstract: A ceramic material is provided by deliberately choosing the additions of oxides to form zirconium oxide, in particular for the use of a layer system which has a high resistance to sintering, high expansion tolerance and low thermal conductivity.
    Type: Application
    Filed: February 26, 2019
    Publication date: December 31, 2020
    Applicant: Siemens Aktiengesellschaft
    Inventors: Arturo Flores Renteria, Werner Stamm
  • Publication number: 20200407283
    Abstract: A graphene foam ceramic composite (GrF-CC) comprises an open cell graphene foam (GrF) surrounded by and infiltrated with a sintered low temperature co-fired ceramic (LTCC) matrix. The GrF-CC can be prepared by infiltrating an open cell GrF with an LTCC slurry, removing the solvent from the slurry with solidification to a ceramic-GrF green body, and sintering the ceramic-GrF green body to form the GrF-CC. Sintering by spark plasma sintering (SPS) allows an LTCC GrF-CC that has a density of at least 90%.
    Type: Application
    Filed: September 15, 2020
    Publication date: December 31, 2020
    Applicant: The Florida International University Board of Trustees
    Inventors: Arvind Agarwal, Benjamin Boesl, Cheng Zhang, Tony Thomas, Pranjal Nautiyal
  • Publication number: 20200407284
    Abstract: The invention provides compositions, systems and methods for controlling loss of nutrients and other substances from planting sites.
    Type: Application
    Filed: March 4, 2020
    Publication date: December 31, 2020
    Applicant: WaterScience, Inc.
    Inventor: Robert J. Littmann
  • Publication number: 20200407285
    Abstract: The invention relates to agriculture, in particular to the processing of carbon-containing material to obtain a humus-containing product. A method for processing a carbon-containing material to obtain a humus-containing product by exposing it to a mixture of bacteria consisting of the strains Acinetobacter calcoaceticus VKPM (Russian National Collection of Industrial Microorganisms) V-4883, Pseudomonas denitrificans VKPM V-4884, Pseudomonas sp. “longa” VKPM V-4885 in an amount of (6-8)×109, (3-4)×109 and (2-3)×109 cells per 1 L of solution, respectively, in the presence of a phosphorus-containing additive, under aerobic conditions and while stirring, wherein the carbon-containing material is firstly ground to 0.5 mm in a wet mill while sapropel is simultaneously added in an amount of 5-10 wt %, and grinding is carried out for 30 minutes, the resulting mixture is sent into a mixer, into which aluminium industry waste in the form of dust from the cleaning of carbon electrodes with a particle size up to 0.
    Type: Application
    Filed: May 16, 2019
    Publication date: December 31, 2020
    Inventors: Yuriy Borisovich TOLKACHNIKOV, Konstantin Yur'evich TOLKACHNIKOV, Yuriy Vladimirovich KOS'YANENKO, Vyacheslav Anatol'yevich TITOV, Dmitriy Nikolayevich KUZNETSOV, Artur Mikhaylovich GORBUNOV
  • Publication number: 20200407286
    Abstract: The Earthginuity Composting System is an organic waste composting system. It consists of three steps/components. The first step is using a free-standing cylindrical tube that goes in the kitchen. Organic waste goes into the tube. The second step is the Phase 1 Bin. It is a square-shaped plastic bin that sits on raw earth, and it's about thirty three gallons in volume. It has drainage holes at the bottom and two pegs protruding from the front to serve as “anchors” for dumping. The final component is the two Earth Grids. They are three by three feet, sandbox-like squares with NO bottoms and liquid-tight lids. The lack of a bottom to the Earthgrids allows for sitting on raw earth to attract ground bugs/bacteria. The lids have rain holes. You can open, close, and empty the Earth Grids with a Shepherd's Staff (hooked pole).
    Type: Application
    Filed: June 25, 2019
    Publication date: December 31, 2020
    Inventor: Alexander Joseph Stokes
  • Publication number: 20200407287
    Abstract: A sleeve for the construction of a hose pipe extends about a longitudinal axis. The sleeve has greater elongation capacities in one direction than in the other with respect to the longitudinal axis.
    Type: Application
    Filed: June 27, 2018
    Publication date: December 31, 2020
    Applicant: EXEL INDUSTRIES
    Inventor: Pierrick LANCIEN
  • Publication number: 20200407288
    Abstract: The present disclosure relates to pyrophoric pellets that break apart into individual particulates or agglomerates when exposed to air and emit infrared radiation. The pyrophoric pellets include: (a) about 35 to about 95 wt. % of pyrophoric particles; (b) about 0.05 to about 30 wt. % of one or more thermally expandable particles; (c) about 1 to about 40 wt. % of one or more additives that modify IR signature; and (d) optionally, one or more additives that produce smoke at a temperature of 150° C. or greater. The pyrophoric pellets are particularly useful as countermeasures to protect against incoming missiles.
    Type: Application
    Filed: July 16, 2019
    Publication date: December 31, 2020
    Inventor: Andrew DAVIS
  • Publication number: 20200407289
    Abstract: A method of converting one or more alkanes to one or more alkenes that includes a) providing a first stream containing one or more alkanes and oxygen to an oxidative dehydrogenation reactor; b) converting at least a portion of the one or more alkanes to one or more alkenes in the oxidative dehydrogenation reactor to provide a second stream exiting the oxidative dehydrogenation reactor containing one or more alkanes, one or more alkenes, oxygen, carbon monoxide and optionally acetylene; and c) providing the second stream to a second reactor containing a catalyst that includes a group 11 metal to convert a least a portion of the carbon monoxide to carbon dioxide and reacting the acetylene.
    Type: Application
    Filed: March 8, 2019
    Publication date: December 31, 2020
    Applicant: NOVA Chemicals (International) S.A.
    Inventors: Vasily Simanzhenkov, Shahin Goodarznia, Kamal Serhal, Xiaoliang Gao, Yoonhee Kim
  • Publication number: 20200407290
    Abstract: Benzene is transalkylated with existing aromatic alkyl groups in a hydrocracking reactor by feeding a benzene stream and alkylated aromatic compounds to a hydrocracking unit. Alkyl groups migrate from heavier alkylated aromatic compounds to the benzene compounds during transalkylation in the hydrocracking unit. The hydrocracking conditions do not prevent the alkyl groups from transferring from one benzene ring to another benzene ring.
    Type: Application
    Filed: June 28, 2019
    Publication date: December 31, 2020
    Inventors: Stanley Joseph Frey, Gavin Paul Towler, Rajeev Gautam
  • Publication number: 20200407291
    Abstract: Co-feeding sulfolane into a transalkylation reactor along with the aromatic hydrocarbon feed(s) can improve benzene purity of the benzene product stream produced from the transalkylation product mixture, especially at the beginning phase of a catalyst cycle.
    Type: Application
    Filed: May 12, 2020
    Publication date: December 31, 2020
    Inventors: Jesus A. Ramos, Robert G. Tinger, Paul Podsiadlo, Todd E. Detjen, Kathleen M. Keville
  • Publication number: 20200407292
    Abstract: Disclosed is a fluorination method comprising providing an aryl fluorosulfonate and a fluorinating reagent to a reaction mixture; and reacting the aryl fluorosulfonate and the fluorinating reagent to provide a fluorinated aryl species. Also disclosed is a fluorination method comprising providing, a salt comprising a cation and an aryloxylate, and SO2F2 to a reaction mixture; reacting the SO2F2 and the ammonium salt to provide a fluorinated aryl species. Further disclosed a fluorination method comprising providing a compound having the structure Ar—OH to a reaction mixture; where Ar is an aryl or heteroaryl; providing SO2F2 to the reaction mixture; providing a fluorinating reagent to the reaction mixture; reacting the SO2F2, the fluorinating reagent and the compound having the structure Ar—OH to provide a fluorinated aryl species having the structure Ar—F.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 31, 2020
    Inventors: Melanie S. SANFORD, Douglas BLAND, Patrick S. HANLEY, Megan A. CISMESIA, Sydonie D. SCHIMLER
  • Publication number: 20200407293
    Abstract: The present invention relates to a process for producing 2,3,3,3-tetrafluoropropene, comprising the steps of: a) providing a stream A comprising at least one of the compounds selected from the group consisting of 2-chloro-3,3,3-trifluoropropene and 2,3-dichloro-1,1,1-trifluoropropane; b) in a reactor, bringing said stream A into contact with HF in the presence or absence of a fluorination catalyst in order to produce a stream B comprising 2,3,3,3-tetrafluoropropene; characterized in that the electrical conductivity of said stream A provided in step a) is less than 15 mS/cm.
    Type: Application
    Filed: March 4, 2019
    Publication date: December 31, 2020
    Applicant: Arkema France
    Inventors: Laurent WENDLINGER, Dominique DEUR-BERT, Anne PIGAMO
  • Publication number: 20200407294
    Abstract: The present specification provides a method for preparing a styrene monomer including preparing a styrene monomer of Chemical Formula 2 by reacting a compound represented by Chemical Formula 1 in the presence of phosphoric acid, wherein the phosphoric acid is used in 100 mol % or greater based on 100 mol % of the compound represented by Chemical Formula 1.
    Type: Application
    Filed: July 27, 2018
    Publication date: December 31, 2020
    Applicant: LG Chem, Ltd.
    Inventors: Byungsoo Kang, Myung Jin Kong, Hyunjik Yi, Wonjae Lee
  • Publication number: 20200407295
    Abstract: A method for producing tetrafluoromethane as follows is unlikely to damage a reaction apparatus and can produce tetrafluoromethane safely, inexpensively, and stably. To a raw material liquid containing a fluorinated hydrocarbon represented by chemical formula CpHqClrFs (wherein p is an integer of 3 to 18, q is an integer of 0 to 3, r is an integer of 0 to 9, and s is an integer of 5 to 30) and having no carbon-carbon unsaturated bond, fluorine gas is introduced, and concurrently a reaction inducer is introduced in a gas state, giving tetrafluoromethane. The reaction inducer is reacted with fluorine gas to induce a reaction of forming tetrafluoromethane from the fluorinated hydrocarbon and the fluorine gas and is at least one reaction inducer selected from a hydrocarbon gaseous at normal temperature and pressure and hydrogen gas.
    Type: Application
    Filed: December 25, 2018
    Publication date: December 31, 2020
    Applicant: SHOWA DENKO K.K.
    Inventors: Yohsuke FUKUCHI, Tomokazu SUGAWARA, Shinya OGURO, Hiroshi KOBAYASHI
  • Publication number: 20200407296
    Abstract: The invention relates to a process comprising contacting a composition comprising a (hydro)halocarbon and a compound of formula Rf—C?CX with a basic solution comprising an hydroxide, an alkoxide and/or an amide to reduce the concentration of Rf—C?CX, wherein Rf is a perfluorinated alkyl group and X is H, F, Cl, Br, or I. The invention further relates to process for preparing a (hydro)halocarbon comprising (i) converting a starting material, optionally in the presence of HF and/or a catalyst, to a composition comprising the (hydro)halocarbon and a compound of formula Rf—C?CX, wherein Rf is a perfluorinated alkyl group and X is H, F, Cl, Br, or I; (ii) contacting the composition with a basic solution comprising an hydroxide, an alkoxide and/or an amide to reduce the concentration of the compound of formula Rf—C?CX; and (iii) recovering the (hydro)halocarbon.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Applicant: Mexichem Fluor S.A. de C.V.
    Inventor: Andrew Paul Sharratt
  • Publication number: 20200407297
    Abstract: There are provided a solvent composition which is excellent in solubility of various organic substances and excellent in detergency and a drying property, and has no adverse effect on a global environment and is excellent in stability; a cleaning method using the solvent composition; a method of forming a coating film; a heat transfer fluid including the solvent composition; and a heat cycle system using the heat transfer fluid. A solvent composition including 1-chloro-2,3,3-trifluoro-1-propene and 1-chloro-3,3-difluoro-1-propyne, a cleaning method of bringing the solvent composition and an article into contact with each other, a method of dissolving a nonvolatile organic compound in the solvent composition to produce a coating film-forming composition and evaporating the solvent composition after applying the coating film-forming composition on an article to be coated, to form a coating film, a heat transfer fluid including the solvent composition, and a heat cycle system using the heat transfer fluid.
    Type: Application
    Filed: September 14, 2020
    Publication date: December 31, 2020
    Applicant: AGC Inc.
    Inventors: Masahiko Nakamura, Hiroaki Mitsuoka, Mari Ichinokawa, Atsushi Fujimori, Hidekazu Okamoto
  • Publication number: 20200407298
    Abstract: A method of producing petrochemicals using a hydrocarbon fuel cell includes the steps of operating the fuel cell to produce electricity, thermal energy, and one or more exhaust stream, the one or more exhaust stream comprising at least a carbon-containing gas and water, reacting at least a portion of the exhaust stream with the reactant stream of natural gas to produce one or more petrochemical streams in a reactor, and heating one or more reactants using at least a portion of at least one of the electricity and the thermal energy.
    Type: Application
    Filed: September 6, 2020
    Publication date: December 31, 2020
    Inventors: Jose Lourenco, MacKenzie Millar
  • Publication number: 20200407299
    Abstract: In a method, device, catalyst and a method for producing a catalyst for the catalytic conversion of a substance mixture containing glycerol to propanol in a fixed-bed reactor, substrates of the catalyst have inorganic materials and/or metal oxides. The substrates have a pore diameter at the surface of between 10 and 25 angstroms, preferably between 12 and 20 angstroms, particularly preferably 15 angstroms.
    Type: Application
    Filed: February 28, 2019
    Publication date: December 31, 2020
    Inventor: Paul SCHÖFFL
  • Publication number: 20200407300
    Abstract: The present disclosure relates to a method and an apparatus for decomposing a phenolic by-product generated in a bisphenol A preparation process, the method including: a step (S10) of feeding the phenolic by-product to a multistage reactive distillation column; a step (S20) of separating the phenolic by-product into an upper discharge stream containing an active component, a side discharge stream containing acetophenone, and a bottom discharge stream containing tar by the multistage reactive distillation column; and a step (S30) of mixing the side discharge stream discharged from the multistage reactive distillation column and the bottom discharge stream discharged from the multistage reactive distillation column to form a mixed discharge stream.
    Type: Application
    Filed: October 15, 2019
    Publication date: December 31, 2020
    Inventors: Min Suk Kang, Sang Beom Lee, Joon Ho Shin
  • Publication number: 20200407301
    Abstract: The present disclosure is directed to 1-(4-methyl cyclohex-1-en-1-yl)ethan-1-one derivatives having unique and desired flavor and/or fragrance characteristics, as well as the synthesis and application of the derivatives. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients to modify or enhance already existing fragrance compositions, solvents, media, and the like.
    Type: Application
    Filed: March 8, 2019
    Publication date: December 31, 2020
    Inventors: Maureen Blandino, Michael E. Lankin, Louis J. Lombardo
  • Publication number: 20200407302
    Abstract: Provided is a process for preparing acrolein by catalytic gas phase oxidation comprising (a) providing a reaction gas comprising (i) 5 to 10 mol % propylene, (ii) 0.02 to 0.75 mol % propane, and (iii) 0.25 to 1.9 mol % of a fuel mixture comprising at least one of methane and ethane, wherein the molar ratio of the total amount of propane, methane, and ethane to the total amount of propylene is from 0.01:1 to 0.25:1, and (b) contacting the reaction gas with a mixed metal oxide catalyst comprising one or more of molybdenum, bismuth, cobalt, and iron.
    Type: Application
    Filed: February 21, 2019
    Publication date: December 31, 2020
    Inventors: Donald A. Ebert, Timothy Allen Hale, Brian Robert Keyes, Justin Rose, Jinsuo Xu
  • Publication number: 20200407303
    Abstract: Disclosed is a process for the oxidation of at least one chroman (C1) in a solvent mixture comprising at least two solvents or in a C-bearing solvent, with a gaseous compound comprising, essentially consisting of, or consisting of oxygen in the presence of a copper catalyst, said copper catalyst exhibiting the oxidation state (+1) or (+2). A further part of the disclosure is a composition comprising at least one chroman (C1) and/or at least one quinone (C30), a solvent mixture comprising at least two solvents or a C-bearing solvent, a copper catalyst, said copper catalyst exhibiting the oxidation state (+1) or (+2) and a gaseous compound comprising, essentially consisting or consisting of oxygen. A quinone preparation and a process of making same is also part of the invention.
    Type: Application
    Filed: February 12, 2019
    Publication date: December 31, 2020
    Inventors: Karin SCHEIN-ALBRECHT, Wolfgang SIEGEL
  • Publication number: 20200407304
    Abstract: The present invention concerns a process and intermediates for the manufacture of difluoro acetyl chloride. The invention further concerns a process for the manufacture of an agrochemically or pharmaceutically active compound, which comprises the process and intermediate for the manufacture of difluoro acetyl chloride for the manufacture of difluoro acetyl chloride or its intermediate.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 31, 2020
    Inventors: Etienne SCHMITT, Janis JAUNZEMS
  • Publication number: 20200407305
    Abstract: A process for producing acetic acid that involves operating the flash vessel and first column at the lowest possible pressure for a given production rate is described. Low pressures are achieved by operating on a back pressure established by a vapor discharge from an absorbing system. This reduces the pressure differential to allow steady and efficient acetic acid production.
    Type: Application
    Filed: September 15, 2020
    Publication date: December 31, 2020
    Inventor: Ronald D. SHAVER
  • Publication number: 20200407306
    Abstract: Provided is a process for preparing acrylic acid comprising (1) preparing acrolein by catalytic gas phase oxidation comprising (a) providing a reaction gas comprising (i) 5 to 10 mol % propylene, (ii) 0.02 to 0.75 mol % propane, and (iii) 0.25 to 1.9 mol % of a fuel mixture comprising at least one of methane and ethane, wherein the molar ratio of the total amount of propane, methane, and ethane to the total amount of propylene is from 0.01:1 to 0.25:1, (b) contacting the reaction gas with a first mixed metal oxide catalyst to form a mixture comprising acrolein, wherein the first mixed metal oxide catalyst comprises one or more of molybdenum, bismuth, cobalt, and iron, and (2) contacting the acrolein mixture with a second mixed metal oxide catalyst to form a mixture comprising acrylic acid, wherein the second mixed metal oxide catalyst comprises one or more of molybdenum, vanadium, tungsten, copper, and antimony.
    Type: Application
    Filed: February 21, 2019
    Publication date: December 31, 2020
    Inventors: Donald A. Ebert, Timothy Allen Hale, Brian Robert Keyes, Justin Rose, Jinsuo Xu
  • Publication number: 20200407307
    Abstract: The present disclosure relates to a process for the manufacturing of a (meth)acrylic anhydride, wherein the process comprises the steps of: A. providing a flow reactor comprising a reaction chamber; B. providing reactants and reagents comprising: a) a (meth)acryloyl halide; b) an organic solvent; c) a (meth)acrylic acid; d) and either: i. a tertiary amine; or ii. an inorganic base and a polar solvent; and C. incorporating the reactants and reagents into the reaction chamber of the flow reactor, thereby forming a reaction product stream comprising the (meth)acrylic anhydride. In another aspect, the present disclosure is directed to the use of a polar solvent for the manufacturing of a (meth)acrylic anhydride in a flow reactor.
    Type: Application
    Filed: February 6, 2019
    Publication date: December 31, 2020
    Inventors: Rudolf J. Dams, Rudy W. Van Campenhout, Matthias Conradi, Marine Movsisyan, Christian V. Stevens
  • Publication number: 20200407308
    Abstract: The present disclosure relates to a preparation method of an acrylic ester compound. The preparation method of an acrylic ester compound according to the present disclosure enables the use of acrylic anhydride as a reactant instead of acryloyl chloride, which is difficult to handle, by using an alkane diamine as a catalyst. Therefore, not only can the reaction be carried out at a low temperature, but also conversion to an acrylic ester compound and a yield of the acrylic ester compound can be improved.
    Type: Application
    Filed: May 15, 2019
    Publication date: December 31, 2020
    Applicant: LG Chem, Ltd.
    Inventors: Ji Eun Kim, Won Taeck Lim, Yongjin Kim, Wonmun Choi
  • Publication number: 20200407309
    Abstract: A method for preparing norbornyl (meth)acrylate by reacting norbornene with (meth)acrylic acid in the presence of boron trifluoride as catalyst, wherein e) boron trifluoride is initially charged in (meth)acrylic acid, f) the initial charge is heated to a temperature of 75 to 110° C., g) norbornene is added and h) the norbornyl (meth)acrylate obtained is isolated from the reaction mixture. A method for preparing norbornyl (meth)acrylate by reacting norbornene with (meth)acrylic acid in the presence of boron trifluoride as catalyst, wherein e) boron trifluoride is initially charged in an organic solvent, f) the initial charge is heated to a temperature of 75 to 110° C., g) a mixture comprising norbornene and (meth)acrylic acid is added and h) the norbornyl (meth)acrylate obtained is isolated from the reaction mixture.
    Type: Application
    Filed: January 22, 2018
    Publication date: December 31, 2020
    Inventors: ANDREA MISSKE, Christoph FLECKENSTEIN, Friederike FLEISCHHAKER
  • Publication number: 20200407310
    Abstract: A process for purifying and/or preparing hexamethylenediamine by hydrogenating adiponitrile in the presence of a hydrogenation catalyst and purifying the thus obtained mixture of hexamethylenediamine, impurities, and water.
    Type: Application
    Filed: February 27, 2019
    Publication date: December 31, 2020
    Applicant: BASF SE
    Inventor: Fabien RIVOLLET
  • Publication number: 20200407311
    Abstract: The present invention relates to a process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides by reacting (a) cyclopropylcarbonitrile to a cyclopropylcarbaldehyde, (b) further reacting to a cyclobutanone, or (d) further reacting to an enamide, 5 (c) further reacting to enantiomerically and diastereomerically enriched cyclobutane amines, or (d) further reacting to an enamide and (e) to an enantiomerically and diastereomerically enriched cyclobutylamide to obtain (f) an enantiomerically and diastereomerically enriched cyclobutane amine, and (g) further reacting to an enantiomerically and diastereomerically enriched cyclobutane amide.
    Type: Application
    Filed: November 14, 2018
    Publication date: December 31, 2020
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventors: Raphael DUMEUNIER, Tomas SMEJKAL, Brijnandan Premnath MISHRA, Vijayagopal Raman GOPALSAMUTHIRAM, Edouard GODINEAU, Anthony Cornelius O'SULLIVAN
  • Publication number: 20200407312
    Abstract: A process for synthesizing an azo compound by oxidation of a hydrogen compound in the presence of a catalyst and a compound of formula (I) is described in which R1, R2 and R3 (R1)(R2)C(PO3(R3)2)2??(I) are as defined. The use of a compound of formula (I) as complexing agent for a catalyst is also described.
    Type: Application
    Filed: March 14, 2019
    Publication date: December 31, 2020
    Applicant: Arkema France
    Inventors: Jean-Marc Sage, Jean-Michel Bossoutrot
  • Publication number: 20200407313
    Abstract: The present disclosure relates to a method for preparing L-cysteine hydrochloride hydrate crystals, and L-cysteine hydrochloride hydrate crystals prepared by the method. Through the method for preparing L-cysteine hydrochloride hydrate crystals of the present disclosure, L-cysteine hydrochloride hydrate crystals can be obtained from a natural L-cysteine fermentation broth with a high recovery rate and/or purity without a chemical reaction or the use of an artificial synthetic compound.
    Type: Application
    Filed: January 30, 2019
    Publication date: December 31, 2020
    Applicant: CJ CheilJedang Corporation
    Inventors: Jun-Woo Kim, Jung Min Lee, Se-Hee Jo, Il Chul Kim, In Sung Lee, Jun Young Jung
  • Publication number: 20200407314
    Abstract: There are provided substituted 4-carboxamido-isoindolinone derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase P ARP-2. The compounds of this invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of in-flammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Applicant: NERVIANO MEDICAL SCIENCES S.r.l
    Inventors: Gianluca Mariano Enrico Papeo, Mikhail Yurievitch Krasavin, Paolo Orsini, Alessandra Scolaro
  • Publication number: 20200407315
    Abstract: A compound is represented by a formula (1) below, in which k is an integer of 0 or more, m is an integer of 1 or more, n is an integer of 2 or more. L is a substituted or unsubstituted aromatic hydrocarbon ring having 6 to 30 ring carbon atoms, CN is a cyano group, and D1 and D2 are each independently represented by one of a formula (2), a formula (3) and formula (3x) below, D1 and D2 being optionally mutually the same or different.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 31, 2020
    Applicant: Idemitsu Kosan Co., Ltd.
    Inventors: Satomi TASAKI, Masahiro KAWAMURA, Toshinari OGIWARA, Hitoshi KUMA, Kei YOSHIDA, Keiji OKINAKA
  • Publication number: 20200407316
    Abstract: The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of S1P1 receptor-associated disorders, for example, psoriasis, rheumatoid arthritis, Crohn's disease, transplant rejection, multiple sclerosis, systemic lupus erythematosus, ulcerative colitis, type I diabetes, acne, microbial infections or diseases and viral infections or diseases.
    Type: Application
    Filed: June 8, 2020
    Publication date: December 31, 2020
    Inventors: Robert M. Jones, Daniel J. Buzard, Sangdon Han, Sun Hee Kim, Juerg Lehmann, Brett Ullman, Jeanne V. Moody, Xiuwen Zhu, Scott Stirn
  • Publication number: 20200407317
    Abstract: The present disclosure concerns use of compounds of formula I, or salts thereof, as reactive matrices for desorption and laser ablation ionization spectrometry. The disclosure further concerns compounds of formula II, or salts thereof, and use of compounds of formula II or III, or salts thereof.
    Type: Application
    Filed: March 6, 2019
    Publication date: December 31, 2020
    Inventors: Per ANDRÉN, Luke ODELL, Anna NILSSON, Mohammadreza SHARIATGORJI, Jonas SÄVMARKER
  • Publication number: 20200407318
    Abstract: Disclosed herein are embodiments of a compound that can be used as a supramolecular sensor for determining the presence of analytes (e.g., illicit drugs), and for identifying and/or quantifying the analytes. Also disclosed herein is a parallel synthesis method for making compound embodiments, as well as method embodiments for using the compound embodiments. Array embodiments comprising one or more compound embodiments disclosed herein also are described.
    Type: Application
    Filed: June 24, 2020
    Publication date: December 31, 2020
    Inventors: Meagan Beatty, Fraser Hof, Allison Selinger
  • Publication number: 20200407319
    Abstract: The present invention relates to the field of pharmaceutical chemistry. In particular, the present invention relates to a class of alkynyl pyridine prolyl hydroxylase inhibitors (I). The experiments show that such a compound has good activity of inhibiting prolyl hydroxylase, and can enhance the generation and secretion of erythropoietin in cell or animal models, and thus can promote the generation of red cells, and can be used for the treatment or prevention of anemia, such as chronic kidney disease anemia, and ischemic diseases, including ischemic strokes, myocardial ischemia and other related diseases. The present invention also discloses a method for preparing such a compound.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Inventors: Qidong YOU, Xiaojin ZHANG, Yonghua LEI, Tianhan HU, Xingsen WU, Haopeng SUN, Xiaoke GUO, Xiaoli XU
  • Publication number: 20200407320
    Abstract: Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed.
    Type: Application
    Filed: September 14, 2020
    Publication date: December 31, 2020
    Inventors: Julius F. Remenar, Laura Cook Blumberg, Tarek A. Zeidan
  • Publication number: 20200407321
    Abstract: Cost effective, semi-continuous flow methods and systems for synthesizing the antimalarial drug hydroxychloroquine (HCQ) in high yield are provided. The synthesis method that uses simple, inexpensive reagents to obtain the crucial intermediate 5-(ethyl(2-hydroxyethyl)-amino)pentan-2-one, vertical-integration of the starting material 5-iodopentan-2-one and the integration of continuous stirred tank reactors.
    Type: Application
    Filed: February 25, 2019
    Publication date: December 31, 2020
    Inventors: Frank B. GUPTON, Saeed AHMAD, Hari P.R. GUNURU, Nakul S. TELANG
  • Publication number: 20200407322
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Application
    Filed: September 16, 2020
    Publication date: December 31, 2020
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • Publication number: 20200407323
    Abstract: The present invention provides processes for the preparation of ivacaftor using novel intermediates and a process for its preparation.
    Type: Application
    Filed: September 16, 2020
    Publication date: December 31, 2020
    Applicant: Laurus Labs Limited
    Inventors: Suresh Thatipally, Venkata Krishna Reddy, Venkata Lakshmi Narasimha Rao Dammalapati, Satyanarayana Chava
  • Publication number: 20200407324
    Abstract: Described are polymerizable fused tricyclic compounds of formula I: wherein R1, R2, R3, m, n, t, and rings B, C, and D are as defined herein. The compounds absorb various wavelengths of ultraviolet and/or visible light (such as high energy visible light) and are suitable for incorporation in a variety of products, such as biomedical devices and ophthalmic devices.
    Type: Application
    Filed: May 26, 2020
    Publication date: December 31, 2020
    Inventors: Shivkumar Mahadevan, Dawn D. Wright
  • Publication number: 20200407325
    Abstract: The present invention relates to the compound having Formula (I) or pharmaceutically acceptable salts or solvates thereof, and its use in treating and/or preventing a Tauopathy.
    Type: Application
    Filed: September 14, 2020
    Publication date: December 31, 2020
    Inventors: Nicolas SERGEANT, Luc BUEE, Patricia MELNYK, Marion GAY, Nicolas LE FUR
  • Publication number: 20200407326
    Abstract: The present invention relates to a method of mono-alkylating a piperidine nitrogen in a piperidine derivative with a deuterated lower-alkyl, which comprises protecting the piperidine nitrogen with an aralkyl protective group, lower-alkylating the piperidine nitrogen with a deuterated-lower-alkylating agent under neutral or basic condition, and then deprotecting the aralkyl protective group.
    Type: Application
    Filed: September 6, 2018
    Publication date: December 31, 2020
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Yuya NAKAI, Masashi HAYASHI, Wataru MITSUHASHI