Abstract: [Problem] To provide a decorating powder composition for decorating the surface of a solid cosmetic material, in particular, for obtaining a solid cosmetic material having a beautiful appearance which is decorated with a glossy powder, and a decorating method using the decorating powder composition. [Solution] Provided are a decorating powder composition including a glossy powder which has been surface-treated with a silane compound or a silazane compound, and a method for decorating a solid cosmetic material, the method including causing the decorating powder composition to adhere to a printing plate and then bringing the printing plate into contact with a surface of the solid cosmetic material to transfer the decorating powder composition to the surface of the solid cosmetic material and decorate the solid cosmetic material.

Abstract: A solid cosmetic composition including at least 15% by weight of a volatile liquid fatty phase, 40% to 85% by weight of a powdery phase having spherical fillers which are surface-treated with a metallic soap. Also a method for preparing such a solid cosmetic composition and to a method for making up the skin or lips using same.

Abstract: A cosmetic pad, which may be useful, for example, for cleansing or other cosmetic-related activity, includes an upper portion, a lower portion coupled to the upper portion, and a non-porous covering. The non-porous covering is disposed around at least the upper portion. The upper portion has a lower durometer than the lower portion.

Abstract: Disclosed are personal care compositions comprising acicular titanium dioxide, which block infrared radiation in the NIR spectral range, and methods for making them.

Abstract: There is provided a spherical organic-inorganic composite particle having good biodegradability. The organic-inorganic composite particle according to the present invention includes 1 to 79% by weight of a silica component and 21 to 99% by weight of a biodegradable plastic. The organic-inorganic composite particle has an average particle diameter d1 of 0.5 to 25 ?m, a true density of 1.03 to 2.00 g/cm3, and a sphericity of 0.80 or more. A cosmetic product including the organic-inorganic composite particle having such properties has excellent texture properties.

Abstract: The present disclosure provides a water in oil type cosmetic composition that prevents syneresis and exhibits favorable stability. A water in oil type cosmetic composition for preventing syneresis of the present disclosure is characterized by containing a compound which is solubilized by being neutralized as an active component. In addition, a preferred embodiment of the water in oil type cosmetic composition for preventing syneresis of the present disclosure is characterized by the compound which is solubilized by being neutralized being a water soluble compound which has a sulfonic acid group. Further, a water in oil type cosmetic of the present disclosure is characterized by containing: a compound which is solubilized by being neutralized; a gelling agent; water; and a powder component; the viscosity of the water in oil cosmetic being greater than or equal to 7000 mPa·s.

Abstract: Nanoemulsions as emulsion additives are prepared to stabilize actives and prevent formulation discoloration. The nanoemulsions have at least 30% by weight oil and are suitable to add to emulsions and/or structured water to produce color stable end use skin benefit compositions.

Abstract: Disclosed are a magnetic eye line, a liquid eyeliner and a gel eyeliner, and a false eyelash corresponding thereto and a wearing method therefor, wherein the eye line contains iron oxide black, and a plurality of small magnets are evenly distributed along a stem of the false eyelash. The liquid or gel eyeliner disclosed in the present invention is resistant to water, sweat and oils after application, is long lasting and smudge-proof, and has no side effects on the eye skin; magnetic eye lines drawn thereby contain iron oxide black as a magnetic substance, have a stronger magnetic property and can adsorb the false eyelash with small magnets, such that the process of wearing the false eyelash is simple, and the false eyelash is aesthetic and does not easily separate after wearing, and is environmentally friendly and safe.

Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.

Abstract: A phosphorous compound such as STMP is used as a cross-linking agent while making a starch nanoparticle in an emulsion process. Negative charge of the nanoparticle is reduced or reversed by adding cations and/or cationizing the starch optionally while forming the nanoparticles. Anionic active agents, such as fluoride or fluorescein, are optionally incorporated into the nanoparticle during the formation process. For example, a fluoride salt can also be used, which promotes the crosslinking reaction while also providing fluoride in the nanoparticle. The retention of both calcium and fluoride in the nanoparticle is improved when both salts are used. Alternatively, the nanoparticle may be used without added calcium and/or fluoride. The nanoparticles may be useful for tooth remineralization, the treatment of dentinal hypersensitivity, to treat caries, or as a diagnostic agent to locate carious lesions.

Abstract: The present disclosure relates to the use of kaolin as an opacifier in cosmetic compositions, cosmetic compositions comprising kaolin and methods of making said cosmetic compositions.

Abstract: Booster oils with stable oil soluble actives are described. The oils are suitable to be combined with end use compositions in order to enhance the compositions efficacy and ensure superior topical benefits to consumers after application.

Abstract: Described herein, are personal care compositions comprising a cleanser base comprising at least one cleanser selected from a soap and a surfactant; and an effective amount of an antibacterial system comprising a combination of phenoxyethanol and piroctone, or a salt thereof. Methods of making and using these compositions are also described.

Abstract: Alcohol-based hand conditioners are provided. The alcohol-based hand conditioners have superior aesthetics suitable for use in rapid workflow environments. They are non-greasy and low residue, and thus do not leave a sticky or tacky feeling on the hands following application.

Abstract: Described are compositions containing quinones that show activity in enhance DNA repair and/or prevent damage to DNA. The quinones are thymoquinone, lapachol, myrtucommulone C, or mixtures thereof, and can be formulated into cosmetic compositions for topical administration to a subject in need thereof. The cosmetic compositions can also include sunscreens, surfactants, sunless tanning agents, desquamation agents, antiperspirants, colorants, preservatives and mixtures; and a cosmetically acceptable carrier. The compositions should find use in methods for treating the signs of ageing in mammals via topical application to the skin or hair of the mammals.

Abstract: Provided is a cleaner composition which causes no malfunction due to clogging even when contained in a pump foamer container, or the like, and repeatedly used, and is excellent in resilience and persistence of foam, and feeling after washing off. The cleaner composition includes a soap that is obtained by neutralizing a higher fatty acid with sodium N-methyltaurate, and a polymer including dimethyl diallyl ammonium chloride as a monomer unit and having a molecular weight of 200000 or less.

Abstract: Compositions and methods of manufacture for an extended time-release fragrance comprising volatile organic compounds. A composition of the disclosure includes an effective amount of a volatile organic compound for providing a fragrance that can be sensed by a user and fractionated coconut oil comprising caprylic acid and capric acid.

Abstract: The invention relates to liquid compositions for use with hair removal devices comprising a metathesized unsaturated polyol ester for improved lubrication.

Abstract: Use of a non-ionic deep eutectic mixture consisting of A and B, A being R1R2N—CO—NR3R4 and B being selected from the group consisting of R5R6N—CO—CH3 and R7R8N—CO—NR9R10, and wherein each of R1-R10 is independently H, CH3 or alkyl, as a solvent or dispersant in chemical synthesis, material synthesis or fabrication, chemical or enzymatic catalysis, food, cosmetic or pharmaceutical formulation, separation or partitioning, heat transfer, and as detergents or cleaners, as well as such mixtures, is disclosed.

Abstract: A skin- or hair-cleansing composition including a component (A), which is an aqueous gelling agent represented by general formula (1) described in the specification, and a component (B), which is an anionic surfactant, wherein the component (A) presents a viscosity of an aqueous solution containing 1 mass % of at 25° C. of 1,000 to 5,000 mPa·s and a clouding point of the aqueous solution containing 1 mass % of component (A) of 60° C. to 80° C., and has a weight average molecular weight of 10,000 to 30,000; a method for producing the aqueous gelling agent and a method for producing the skin- or hair-cleansing composition are provided.

Abstract: Oral care compositions comprising citrulline and stannous ion source with a specific pH range are provided for promoting Gum Health of a user.

Abstract: Oral care compositions comprising a neutral amino acid and stannous ion source are provided for promoting Gum Health of a user.

Abstract: Oral care compositions comprising an amino acid and stannous ion source, especially in the absence of zinc ion source, are provided for promoting Gum Health of a user.

Abstract: Certain liquid personal care cleaning compositions containing: linalool, a linalool isomer, or combinations thereof; and hinokitiol exhibit effective antibacterial properties.

Abstract: An oral care composition including rottlerin in an amount sufficient to reduce a growth of gram-positive bacteria in a mouth treated with the oral care composition.

Abstract: Heptahydroxyflavan or a salt, isomer, hydrate or solvate thereof, which is an active ingredient of the present disclosure, can enhance skin elasticity and improve skin wrinkles by inhibiting the activity of MMP-1. In addition, the heptahydroxyflavan or a salt, isomer, hydrate or solvate thereof, which is an active ingredient of the present disclosure, can be used in various compositions such as cosmetics, health functional foods, etc. because it is safe with no cytotoxicity.

Abstract: The invention relates to the non-therapeutic cosmetic use of at least one compound of formula (I) as defined below, as an agent for bleaching, lightening and/or depigmenting keratin materials, especially the skin. The invention also relates to a non-therapeutic cosmetic process for depigmenting, lightening and/or bleaching keratin materials, especially the skin, using these compounds (I).

Abstract: Provided are formulations that interact with the skin microbiome of a human patient such that when applied topically in therapeutically effective amounts at prescribed intervals, the formulations cause an increase in skin firmness, density, smoothness, elasticity and thickness resulting in a skin appearance that reflects overall skin health. In exemplary embodiments formulations include, without limitation, the following active components acting in concert with each other: a prebiotic component, a peptide component, a matrix metalloproteinases (MMPs) inhibitor component; and an antioxidant component; all present in a carrier base. The exemplary embodiments may be in the form of a cream, a lotion, a serum, or a hydrogel that facilitates delivery of these active components into the skin.

Abstract: Disclosed is a method of manufacturing a composition material for skin moisturizing containing a vehicle having a multi-layer globule. The method includes manufacturing a hydrogenated lecithin dispersion solution by adding hydrogenated lecithin to purified water at 70 to 90° C. with agitation to thus perform dispersion, manufacturing a pre-emulsion base by adding a saturated fatty alcohol having 12 to 22 carbon atoms to the hydrogenated lecithin dispersion solution at 70 to 90° C. with agitation to thus perform dispersion, manufacturing a composition material base for skin moisturizing by adding the pre-emulsion base and water-soluble polypeptide to the purified water at 70 to 90° C. with agitation to thus perform dispersion, and manufacturing a multi-layer globule for skin moisturizing including phospholipid bilayers by adding oil to the composition material base for skin moisturizing at 70 to 90° C. with agitation to thus perform dispersion.

Abstract: The present disclosure relates to a composition for improving optical characteristics of skin, which improves changes of optical characteristics of skin and skin texture, changes of skin tone such as dullness, and the like, caused by progress of keratinization, by applying an optical clearing agent to skin, and thereby, it comprises an optical clearing agent in the composition, thereby having an effect of reducing crystallization of constituents as the optical clearing agent penetrates between keratinocytes, and reducing light scattering as the substance for improving optical characteristics penetrated in the keratinocytes remains in the keratinocytes and binds to water, and through this, improving skin clearing, skin tone and skin texture, and therefore, it may be very usefully used as skin external preparation and cosmetic compositions.

Abstract: The present invention relates to topical compositions comprising a saccharide isomerate and at least one acryloyldimethyltaurate polymer comprising alkali metal ions and/or ammonium ions, characterized in that the ratio of alkali metal ions to ammonium ions in the acryloyldimethyltaurate moieties in the at least one polymer is at least 1 as well as to the use of an alkali metal acryloyldimethyltaurate polymer to suppress discoloration in topical compositions comprising a saccharide isomerate and an ammonium acryloyldimethyltaurate polymer.

Abstract: A tooth whitening composition includes a hydrophobic copolymer, a hydrophilic whitening agent and a polar solvent.

Abstract: A fibrous structure with a plurality of fibrous elements. The fibrous elements contain a polymeric structurant; a fatty material with a melting point above 25° C.; a cationic surfactant, which can be selected from the group consisting of a mono-long alkyl amine, a tertiary amine, and combinations thereof; and an oil soluble acid. The oil soluble acid can be selected from the group consisting of salicylic acid, lactic acid, acetic acid, malic acid, succinic acid, sorbic acid, 2,4-dihydroxybenzoic acid, maleic acid, and combinations thereof.

Abstract: The present invention relates to a composition suitable for treating hair comprising a polymer selected from the group consisting of a branched polylysine and a branched polylysine in which to 80% of the amino groups present in the branched polylysine are derivatized so that they bear one or two substituents, and comprising at least one surfactant. Furthermore, the present invention relates to a branched polylysine in which 1 to 80% of the amino groups present in the branched polylysine are derivatized so that they bear one or two substituents, wherein these substituents are acyl groups having 6 to 24 C-atoms. Furthermore, the present invention relates to the use of a branched polylysine or of the branched polylysine in which amino groups are derivatized or of the said composition for treating hair.

Abstract: The present invention concerns a composition comprising a Lycium barbarum extract or Lycium barbarum polysaccharide in combination with a Moringa oleifera extract and a pharmaceutically acceptable carrier. The composition finds application both in the medical field, in the treatment of actinic lesions, precancerous skin lesions, or non-melanoma skin cancer, and in non-therapeutic applications in the treatment of skin damage caused by exposure to the sun's rays, such as photoaging.

Abstract: The present invention relates to a composition comprising ex-vivo expanded adipose tissue derived stem cell (ASC) or ex-vivo expanded adipose tissue-derived stem cells (ASC) mixed with harvested fat tissue at a ratio of 5,0×104?2,0×108 ASCs/mL fat; for example 1,0×105?2,0×107 and the use of ex-vivo expanded adipose tissue-derived stem cells or ex-vivo expanded adipose tissue-derived stem cell enriched fat grafts as an agent for cosmetic breast filling/augmentation or for facial filling/rejuvenation.

Abstract: The present disclosure relates to a method for delivering a mucoadhesive composition to the oral cavity of a subject. The mucoadhesive composition comprises one or more active agents, a mucoadhesive polymer, and water. The present disclosure is further related to a method for treating a disease, disorder, or condition, such as pharyngitis, aphthous stomatitis (canker sore), bacterial infection, radiation-induced mucositis, fibromyalgia, and diabetes, comprising administering the mucoadhesive composition to the oral cavity of a subject. The present disclosure is also related a mucoadhesive composition comprising one or more active agents, a mucoadhesive polymer, and water.

Abstract: Stable aerosol solution formulations comprising glycopyrronium bromide are useful for administration to patients with COPD and other respiratory conditions.

Abstract: The present invention relates to a method to prepare pharmaceutical compositions of sugammadex, to pharmaceutical compositions of sugammadex and uniform pharmaceutical batches of said compositions.

Abstract: A composition comprising a small molecule therapeutic agent and an organic acid compound is described. The small molecule therapeutic agent (i) has a water solubility at room temperature of less than about 1.0 g/L and (ii) is a base. The organic acid is one that (i) has a water solubility at room temperature of between 0.1 and 10 or of less than about 20 g/L, (ii) has a molar mass of less than 500 grams per mole, and/or (iii) maintains a pH of the composition when hydrated in its environment of use of between 3.0-6.5 for a period of at least about 30 days. The organic acid, particularly when it is present in the composition in stoichiometric excess, improves solubility of the small molecule therapeutic agent to provide a composition that delivers the therapeutic agent for a sustained period of time.

Abstract: Topical vaginal compositions are disclosed herein which include silica microspheres and an active ingredient in the amount of 0.001 to 15.0% w/w selected from estradiol, metronidazole, clindamycin, butoconazole, and combinations thereof. The topical compositions provide sustained release of the active ingredient so as to reduce skin irritation.

Abstract: The present invention relates to delivery devices adapted to mechanically dilate a pelvic anatomical canal, the delivery devices comprise a composition formulated as a gel comprising a beneficial or therapeutic agent, said delivery devices being capable of releasing the beneficial or therapeutic agent into the pelvic anatomical canal, specifically into the vaginal canal, and thereby treat vaginal conditions associated with vaginal narrowing, atrophy, or dryness.

Abstract: The present invention provides a stable liquid pharmaceutical formulation containing: an antibody or its antigen-binding fragment; a surfactant; a sugar or its derivative; and a buffer. The stable liquid pharmaceutical formulation according to the present invention has low viscosity while containing a high content of the antibody, has excellent long-term storage stability based on excellent stability under accelerated conditions and severe conditions, and may be administered subcutaneously.

Abstract: The disclosure provides drug delivery formulations that comprise a porous silicon material and a meltable compound, such as a progestin drug, or a meltable composition. The formulations provide for the controlled release of the progestin drug, or other therapeutic agent, over long time periods. In some embodiments, the meltable composition further comprises a melting point suppression agent, where the melting point suppression agent enables the loading of thermally unstable therapeutic agents into the porous silicon material by melt casting that would not otherwise be possible absent the melting point suppression agent. The disclosure additionally provides methods of making and using the drug delivery formulations.

Abstract: Provided herein are methods of treatment, compositions, systems and kits using polymer particles as restraints of neutrophil function. Such methods include, but are not limited to, methods of preventing, treating, and/or ameliorating inflammatory diseases, infections, autoimmune diseases, malignant diseases, and other diseases or conditions in which neutrophils may be implicated. In some embodiments, polymer particles are useful for diagnosing neutrophil related diseases or conditions.

Abstract: The present application relates to pharmaceutical compositions comprising a salt of arsenous acid, such as sodium meta arsenite or potassium meta arsenite, and methods of manufacturing the pharmaceutical compositions.

Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

Abstract: Disclosed are engineered nanovesicles and engineered platelets comprising an exogenous protein and methods for treating cancer comprising administering the same to a subject.