Patents Issued in March 11, 2021
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Publication number: 20210068979Abstract: Systems and methods for placement of both the prosthetic acetabular cup and the prosthetic femoral head which takes account of the patient's particular anatomy, with inter-operative testing of the patient's body to find an optimum positioning (angles) for the components. The system allows a procedure with less pre-operative and inter-operative imaging, providing for reduced radiation exposure for doctors and patients.Type: ApplicationFiled: September 8, 2020Publication date: March 11, 2021Applicant: iHip Surgical, LLCInventors: Anatol Podolsky, Yuri Garbuzov
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Publication number: 20210068980Abstract: A surgical instrument having a first member being engageable with a fastener. A second member includes an expandable portion configured for capturing the fastener. A third member is engageable with the expandable portion to releasably capture the fastener. An actuator connected with the second member and the third member. The actuator includes a threaded inner surface and a threaded coupling member engageable with the threaded inner surface to facilitate axial translation of the second member relative to the third member. Systems, spinal constructs, implants and methods are disclosed.Type: ApplicationFiled: September 9, 2019Publication date: March 11, 2021Inventor: Daniel Paxton Wall
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Publication number: 20210068981Abstract: The invention involves a cannula suitable for the implantation of intervertebral implants into the spine area of an animal, particularly humans. The first end of the dynamically expanding cannula includes a rectangular or oval shaped cannula portion formed from a sandwich style assembly. The second end of the dynamically expanding cannula includes a connection assembly for securing the sandwich construction together. Once inserted, a backing assembly can be removed and a flexible expansion member can be displaced by an implant while a slide guides the implant to create a dynamic opening through which the implant travels to the disc space. A lever is supplied as a portion of the expansion assembly for removing the expansion member after insertion of an intervertebral implant.Type: ApplicationFiled: September 9, 2020Publication date: March 11, 2021Inventors: Wyatt Drake Geist, John Souza, Mark Grubb
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Publication number: 20210068982Abstract: An insertion instrument for expandable spinal implants includes an elongate member, a shuttle, and a worm gear. The elongate member includes a handle portion of a proximal end and an end effector on a distal end, wherein the end effector is configured to be releasably engaged to an expandable spinal implant. The shuttle is slidably disposed within a cavity defined within the end effector and includes a wedged shaped distal end configured to engage an expandable spinal implant. The worm gear is rotatably disposed within the cavity defined in the end effector and is in mechanical communication with the shuttle, such that rotation of the worm gear effectuates movement of the shuttle. Distal movement of the shuttle effectuates articulation of an expandable spinal implant. A method of performing surgery is also disclosed.Type: ApplicationFiled: September 21, 2020Publication date: March 11, 2021Inventors: Megan Carnes, John Donohoe, Scott Jones
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Publication number: 20210068983Abstract: A spinal implant comprises an implant body extending between an anterior surface and a posterior surface. The implant body includes a first vertebral engaging surface and a second vertebral engaging surface. The implant body includes an outer surface that defines an oblique surface. A wall is connectable with the implant body and translatable relative to the oblique surface. Systems and methods are disclosed.Type: ApplicationFiled: November 10, 2020Publication date: March 11, 2021Applicant: WARSAW ORTHOPEDIC INC.Inventors: Anthony J. Melkent, Thomas E. Drochner, Richard A. Hynes, James P. Duncan
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Publication number: 20210068984Abstract: This disclosure is directed to methods for reconstructing an unstable triangular fibrocartilage complex (TFCC). Exemplary methods include preparing, delivering, and fixating a graft within a distal radioulnar joint in a manner that restores the functionality to the TFCC, thereby improving the joint kinematics of the radioulnar joint.Type: ApplicationFiled: September 5, 2019Publication date: March 11, 2021Inventors: Felix RIANO, Christopher ADAMS
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Publication number: 20210068985Abstract: A method comprises the steps of: imaging at least one trial with a patient anatomy; acquiring data points representative of an image of the at least one trial selectively positioned relative to the patient anatomy; displaying the image from a computer monitor; imaging at least one spinal implant with the patient anatomy; and aligning the at least one spinal implant with the image via a display from the computer monitor. Systems, spinal constructs, implants and surgical instruments are disclosed.Type: ApplicationFiled: September 9, 2019Publication date: March 11, 2021Inventors: Jonathan M. Dewey, Fuad N. Mefleh, Cathlene Donaldson
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Publication number: 20210068986Abstract: A surgical system includes a trial connected with a first image guide oriented relative to a sensor to communicate a signal representative of the trial relative to a patient anatomy. A tracking device includes the sensor and communicates with a processor to generate a storable image of the trial relative to the patient anatomy for display from a monitor. A spinal implant is connected with a second image guide oriented relative to the sensor to communicate a signal representative of the spinal implant relative to the patient anatomy. The sensor receives the signal of the second image guide and communicates with the processor to generate an image of the spinal implant in real time for display from the monitor in a configuration to align the spinal implant in real time with the stored image of the trial. In some embodiments, methods, spinal constructs, implants and surgical instruments are disclosed.Type: ApplicationFiled: September 9, 2019Publication date: March 11, 2021Inventors: Jonathan M. Dewey, Fuad N. Mefleh, Cathlene Donaldson
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Publication number: 20210068987Abstract: A method for producing an orthopedic device, wherein the method comprises: providing a main body of the orthopedic device that comprises at least one volume that can be filled with a fluid, at least one supply line to this volume, and a flexible and/or elastic material in at least some sections of the main body in which there is no volume that can be filled with a fluid, arranging the main body on a body part of a patient, at least partially filling the volume with a curable fluid, and curing the curable fluid.Type: ApplicationFiled: May 9, 2019Publication date: March 11, 2021Applicant: Ottobock SE & Co. KGaAInventors: Mario KOPPE, Jonas BORNMANN, Andreas LEINIGER
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Publication number: 20210068988Abstract: A driving assembly for moving a first body part relative to a second body part comprising at least one manipulator unit for body part including a housing for accommodating at least partly of an actuator, a torque/force transmission gear, a partial gear wheel operatively connected with each other and a first connector arranged at a first/tail end of the manipulator unit for coupling with the first body part and a second connector movably arranged at a second/head end of the manipulator unit for coupling with the second body part and driven by the partial gear wheel actuated by the actuator via the torque transmission gear for coupling and moving with the second body part, and preferably an arc channel or rail for guiding back and forth movement of the partial gear wheel.Type: ApplicationFiled: December 5, 2018Publication date: March 11, 2021Inventor: Sze Kit Ho
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Publication number: 20210068989Abstract: The invention relates to a prosthetic foot comprising a base body having a front sole region, a heel body having a rear sole region, and a slot configured to receive at least one spring element, in particular at least one leaf spring, the spring element configured to be pushed or inserted into the slot. In a disposed state, the spring element engages in the base body and the heel body such that the heel body is spring mounted relative to the base body.Type: ApplicationFiled: May 8, 2019Publication date: March 11, 2021Inventors: Jannis BREUNINGER, Franziska GLAS, Bence ROCHLITZ, Carolin TAUBMANN, Clemens RIETH
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Publication number: 20210068990Abstract: Powered limb prostheses with multi-stage transmissions are provided.Type: ApplicationFiled: April 6, 2020Publication date: March 11, 2021Applicant: Freedom Innovations, LLCInventors: Jonathan M. BYARS, Hugo QUINTERO, John CARPENTER
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Publication number: 20210068991Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.Type: ApplicationFiled: November 16, 2020Publication date: March 11, 2021Inventors: Xiaodong Ma, Min-Shyan Sheu, Lincoln Eramo, John Wainwright, Junwei Li
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Publication number: 20210068992Abstract: A bifurcated intravascular stent graft comprises primary stent segments and a primary graft sleeve, forming a main fluid channel and having a side opening therethrough. An external graft channel formed on the primary graft sleeve has a first end communicating with the side opening and an open second end outside the primary graft sleeve, thereby providing a branch flow channel from the main channel out through the side opening and external graft channel. The primary stent segments and graft sleeve engage an endoluminal surface of a main vessel and form substantially fluid-tight seals. The stent graft further comprises a secondary stent graft, which may be positioned partially within the external graft channel, through the open second end thereof, and partially within a branch vessel. The secondary stent graft engages the inner surface of the external graft channel and the endoluminal surface of the branch vessel, thereby forming substantially fluid-tight seals.Type: ApplicationFiled: November 20, 2020Publication date: March 11, 2021Inventor: Stephen F. Quinn
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Publication number: 20210068993Abstract: A vascular implant configured for occluding a vasculature of a patient having a biocompatible polymeric structure formed of a plurality of filaments spaced to maintain surface porosity and an inner radiopaque coil positioned within the longitudinally extending opening of the polymeric structure and attached to the polymeric structure. The polymeric structure and radiopaque coil are attached forming a joint at the distal end.Type: ApplicationFiled: November 20, 2020Publication date: March 11, 2021Applicant: Neurogami Medical, Inc.Inventors: Stephen J. Hebert, Bartosz Bojanowski
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Publication number: 20210068994Abstract: A stent composed by a bioabsorbable network of polymer fibers that can be rearranged upon expansion, accommodating for diameter enlargement without the need of a strut or strut pattern and providing temporary support to a biological duct, is provided. Additionally, a stent is provided where the rearranged fibrous network of its expanded state can act as a scaffold for cell infiltration and promote autologous tissue formation.Type: ApplicationFiled: September 22, 2020Publication date: March 11, 2021Inventors: Bart SANDERS, Maria Sol CABRERA, Franciscus Petrus Thomas BAAIJENS, Patricia Yvonne Wilhelmina DANKERS
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Publication number: 20210068995Abstract: A method of making a method of making a stent includes forming a precursor stent using micro-cladding. The precursor stent includes a plurality of bands made of a first material disposed adjacent to each other and a plurality of connectors connecting each band to an adjacent band. The precursor stent includes a plurality of first connectors configured to remain and a plurality of second connectors made by functionally grading the first material with a second material to create embrittlement. The plurality of second connectors are configured to be removed. The precursor stent is processed to remove the plurality of second connectors without adversely affecting the bands and the plurality of first connectors. The second material may be a radiopaque material.Type: ApplicationFiled: November 2, 2020Publication date: March 11, 2021Inventor: Syamala Pulugurtha
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Publication number: 20210068996Abstract: The invention relates to medical devices and methods of using them. The devices are prostheses which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The prostheses are configured to have a lattice resistant to dilation and creep, which is defined by a plurality of openings. The prosthesis may also optionally have a stent disposed proximal to the lattice. In exemplary embodiments, the fluoropolymer is expanded polytetrafluoroethylene. The composite materials exhibit high elongation while substantially retaining the strength properties of the fluoropolymer membrane. In at least one embodiment, the lattice is made of a composite material that includes a least one fluoropolymer membrane including serpentine fibrils and an elastomer. A lattice including a generally tubular member formed of a composite material including a least one fluoropolymer membrane containing serpentine fibrils and an elastomer is also provided.Type: ApplicationFiled: November 16, 2020Publication date: March 11, 2021Inventors: Joseph R. Armstrong, Edward H. Cully, Jeffrey B. Duncan, Mark Y. Hansen, William D. Montgomery, Wendy J. Terry
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Publication number: 20210068997Abstract: The present disclosure describes implantable medical devices comprising covers, such as a balloon cover. Such devices can comprise a first layer of a porous polymeric material, such as ePTFE, surrounded by layers of a porous polymeric material having an imbibed elastomer, such as polyurethane. The cover can be used to assist in deployment of an expandable implant, such as a stent-graft, within the body of the patient.Type: ApplicationFiled: November 16, 2020Publication date: March 11, 2021Inventors: Deenu G. Kanjickal, James J. Nickerson, Thomas G. Triebes
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Publication number: 20210068998Abstract: A conveyor for an implant having at least one cavity, including a conveying handle, a conveying cable, and a core wire. The conveying cable is a tubular body, a proximal end of the core wire is connected to the conveying handle, and a distal end of the core wire penetrates a distal end of the conveying cable from a proximal end of the conveying cable; a first control is provided on the conveying handle, and when the implant is connected to the distal end of the conveying cable, the first control controls the distal end of the core wire to extend into the implant to straighten the curved implant, or the first control controls the core wire to withdraw from the implant to restore the implant to a preset shape. The conveyor can load and release the implant on the conveyor, and be used in the entire implanting process.Type: ApplicationFiled: December 18, 2018Publication date: March 11, 2021Applicant: LIFETECH SCIENTIFIC (SHENZHEN) CO., LTDInventors: Shujun LI, Siyi LI, Anning LI
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Publication number: 20210068999Abstract: Various embodiments of the present invention provide a method and a system. The system having an appetite control device for covering a plurality of teeth, wherein the appetite control device comprises an arcuate shape having an outer sidewall, an inner sidewall and a top wall connecting the inner sidewall and outer sidewall to form a channel, wherein the channel is configured for receiving a plurality of teeth, wherein the appetite control device includes a larger width at ends and a narrower width at a front. The system further includes a user device having a memory and a processor configured to execute executable instructions stored in the memory to receive data associated with usage of the appetite control device and determine an output data associated with appetite information of the user based on analysis of the received data using a pre-trained machine learning model.Type: ApplicationFiled: November 18, 2020Publication date: March 11, 2021Inventor: Kendall Ann Whitney
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Publication number: 20210069000Abstract: A device that decompresses the lower spine while the wearer is seated or standing. The device includes two belt-shaped straps. The first strap circles the upper torso just below the breast line. The second strap circles the waist at or slightly above the normal belt line riding on the hip. In embodiments of the invention, the lower strap can be a normal belt. The straps can be equipped with pockets that are aligned along the upper edge of the upper strap and the lower edge of the lower strap designed to receive and hold flat splints. Typically, two rigid flat splints extend vertically between the straps centered laterally on the left and right sides of the torso. When the device is worn, it decompresses the lower spine when the person stands or sits.Type: ApplicationFiled: July 24, 2020Publication date: March 11, 2021Applicant: Leona E LLCInventor: Paul Sacco
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Publication number: 20210069001Abstract: The present invention discloses an enhanced design of the orthotic device with symmetrical estimations in stature and side width to provide enhanced stability. The assembly has three separate connectable levels which fit as blocks and enable the user to adjust each level as per individual requirements.Type: ApplicationFiled: September 6, 2019Publication date: March 11, 2021Inventor: Diego Caban Delgado
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Publication number: 20210069002Abstract: A neck collar is provided, including: a neck sleeve, a chin support and an adjustment mechanism. The chin support is swingably connected to the neck sleeve. The adjustment mechanism includes at least one linking member and at least one driving member with which the linking member is co-movably connected. Each of the at least one linking member is movably connected to the neck sleeve and movably abutted against the chin support. The at least one driving member is externally operable and adjustable to drive the at least one linking member to move relative to the neck sleeve and to move relative to the chin support, simultaneously, between a first position and a second position. When the at least one linking member is moved toward the second position, the at least one linking member drives the chin support to swing upwardly relative to the neck sleeve.Type: ApplicationFiled: September 10, 2019Publication date: March 11, 2021Inventor: YU-CHIEN WANG
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Publication number: 20210069003Abstract: An apparatus for treating clubfoot is provided that comprises a pair of vertically stacked and parallel cross bars that are connected to shoe attachment member via four hinges to define a parallelogram shaped gap therebetween. As the user raises a knee, one shoe attachment member can be displaced via the hinges (primarily in the y-axis or anterior/superior plane) relative to the other shoe attachment member, while the distance between the crossbars remains constant.Type: ApplicationFiled: September 10, 2020Publication date: March 11, 2021Inventors: Thomas M. Cook, Nicole M. Grosland, Jose Morcuende
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Publication number: 20210069004Abstract: An elbow brace for supporting a wearer's elbow in a desired position when using a portable electronic device to mitigate “tech neck” is made unobtrusive by incorporation into a shoulder bag having a length-adjustable shoulder strap. A flexible bag assembly comprises opposite first and second panels of flexible sheet-like material connected to define an interior compartment having a volume. An upper bag mouth is disposed between edges of the panels, with fastenings connecting its opposite ends of the edges. An elbow-receiving sleeve of flexible sheet-like material is attached in the upper bag mouth and can be opened into a generally frustoconical form, for supporting a bent elbow such that, in use, both forearm and upper arm extend from an outer end elbow-receiving sleeve. In a closed state the elbow-receiving sleeve is flattened such that opposing halves of the elbow-receiving sleeve come together.Type: ApplicationFiled: March 29, 2019Publication date: March 11, 2021Inventor: David K YEUNG
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Publication number: 20210069005Abstract: A system suitable for collecting and transporting urine away from the body of a person or animal may include an assembly having a fluid impermeable casing having a fluid reservoir at a first end, a fluid outlet at a second end, and a longitudinally extending fluid impermeable layer coupled to the fluid reservoir and the fluid outlet and defining a longitudinally elongated opening between the reservoir and the outlet. The assembly can further include a fluid permeable support disposed within the casing with a portion extending across the elongated opening, and a fluid permeable membrane disposed on the support and covering at least the portion of the support that extends across the elongated opening, so that the membrane is supported on the support and disposed across the elongated opening. The assembly can further include a tube having a first end disposed in the reservoir and a second, fluid discharge end.Type: ApplicationFiled: November 3, 2020Publication date: March 11, 2021Inventors: Robert A. Sanchez, Camille R. Newton, Joseph M. Forehand, Raymond J. Newton
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Publication number: 20210069006Abstract: A urine-sampling system for aseptic urine sampling includes a catheter assembly and a sampling-port access device. The catheter assembly includes a urinary catheter, drainage tubing, and a connector fluidly connecting the urinary catheter to the drainage tubing. The connector includes a urine-sampling port. The sampling-port access device includes a tip at an end of a barrel configured to fluidly connect the sampling-port access device to the urine-sampling port of the catheter assembly. Each of the tip of the sampling-port access device and the urine-sampling port has a complementary fastening means for—fastening to the other of the tip of the sampling-port access device and the urine-sampling port. Each of the complementary fastening means ensures proper mating of the tip of the sampling-port access device and the urine-sampling port for aseptic urine sampling. In addition to various urine-sampling systems such as the foregoing, methods of use are also disclosed.Type: ApplicationFiled: May 13, 2019Publication date: March 11, 2021Inventors: Tim Waitkus, Chris Fodouop, Kelsey Leeke, John Gohde
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Publication number: 20210069007Abstract: A wearable urinary collection apparatus for being worn by a user, including an elongate, watertight, flexible receptacle having an entrance opening near one end thereof and an elongate, flexible backflow inhibiting device which is connected to and extends within a portion of the flexible receptacle and also includes an entrance opening to receive the user's penis therein. At least one of the entrance opening of the receptacle and the entrance opening of the backflow inhibiting device is configured to receive the user's penis therein such that urine discharged from the penis flows through the backflow inhibiting device into the receptacle. The receptacle and the backflow inhibiting device are each formed of flexible plastic sheet material and are each configured to collapse flat when not in use, and the backflow inhibiting device has constrictions formed therein for constricting and diverting flow of urine therethrough.Type: ApplicationFiled: November 19, 2020Publication date: March 11, 2021Inventor: William Kyungha JOH
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Publication number: 20210069008Abstract: In an example, a urine collection device includes a covering defining a recessed receptacle and a fluid collection assembly positioned in the recessed receptacle. The fluid collection assembly includes (i) a foam sleeve including a bore, (ii) a shape retaining element positioned in the bore of the foam sleeve and defining a passage, and (iii) a tube extending through the passage defined by the shape retaining element. The shape retaining element can conform the fluid collection assembly to a curved configuration and maintain the curved configuration of the fluid collection assembly until the curved configuration is adjusted. The urine collection further includes a top sheet coupled to the covering. The top sheet and the covering define an internal chamber of the urine collection device. The top sheet is configured to draw urine into the internal chamber and toward the fluid collection assembly.Type: ApplicationFiled: September 7, 2020Publication date: March 11, 2021Inventors: Brett C. Blabas, Kristin M. Sexton, Daniel R. Ulreich, Catherine S. Boulos, Britt O'Halloran
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Publication number: 20210069009Abstract: The disclosure relates to a menstrual cup that can be reused by replacing only a container containing menstrual blood.Type: ApplicationFiled: November 18, 2020Publication date: March 11, 2021Inventor: Kyung-Ran IM
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Publication number: 20210069010Abstract: A method of promoting secretion of a growth hormone includes the step of applying a thermal stimulus to specific sites on a body surface of the subject. The step of applying the thermal stimulus includes the steps of placing two or more guide elements made of two different kinds of metals respectively on at least two different sites of the specific sites, and controlling a temperature of the guide elements to be a range from 40 to 50±5° C., thereby applying the thermal stimulus to the specific sites according to a thermal stimulus pattern so as to increase a rate of blood flow in the subject by 60% or more by the application of thermal stimulus.Type: ApplicationFiled: September 15, 2020Publication date: March 11, 2021Inventor: Kenji Ryotokuji
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Publication number: 20210069011Abstract: A directable, portable appliance in combination with an adjustable set-point digital temperature controller for non-contact remotely monitoring infrared temperatures of a selected area of human skin and activating an electrical fan for directing cooling air over the selected skin areas of individuals experiencing episodes of thermal chaos, i.e., hot flashes.Type: ApplicationFiled: September 11, 2019Publication date: March 11, 2021Inventor: Donald J. Catalano
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Publication number: 20210069012Abstract: Surface treatment devices having a flexible, fluid impermeable enclosure made of a synthetic amorphous silica; and a polydimethlysiloxane fluid contained in the enclosure. The synthetic amorphous silica may be a liquid silicone rubber, for example, s CHT True Skin liquid silicone rubber. The polydimethlysiloxane fluid may be a CHT QM Diluent. The treatment device may be used for heating or cooling a surface, for example, the surface of the human body. The liquid silicone rubber may be a CHT True Skin 10 liquid silicone rubber, and the CHT QM Diluent may be a low viscosity CHT QM Diluent, for example, a CHT QM Diluent having a viscosity of at least 50 centipoise (cps), or at least 1,000 cps. Methods for treating a surface and methods for fabricating a surface treating device are also provided.Type: ApplicationFiled: September 9, 2020Publication date: March 11, 2021Applicant: IMPACT TECHNOLOGIES, LLCInventor: Jason E. Kirshon
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Publication number: 20210069013Abstract: Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).Type: ApplicationFiled: October 30, 2020Publication date: March 11, 2021Inventor: Vijay P. Singh
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Publication number: 20210069014Abstract: The present invention relates to a drop dispenser (1), comprising: —a container part (1B) with an interior volume adapted to be partially filled with a liquid phase (2) and a gaseous phase (3) filling the remainder of the interior volume at ambient pressure, the container part (1B) having a displaceable section (1C), and —a dropper part (1A) in physical connection and in fluid communication with the interior volume of the container part (1B), comprising an outflow channel (5), connecting the interior volume of the container part (1B) to the environment; wherein the outflow channel (5) comprises —a first section (5a) having a proximal end (5ap) and a distal end (5ad), each end having the same or different inner diameter selected independently from each other in the range of 0.09 to 0.19 mm; and —a second section (5b) having a proximal end (5bp) and a distal end (5bd); the proximal end (5bp) having an inner diameter in the range of 1 to 3 mm; the distal end (5bd) having an inner diameter in the range of 0.Type: ApplicationFiled: May 3, 2018Publication date: March 11, 2021Inventors: Frank LÖSCHER, Philip KEMP, Jörg Martin MAUDEN, Eike HOPPMANN, Veronika LÖSSEL, Sybille BURKHARDT
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Publication number: 20210069015Abstract: A probe tip assembly includes an optical fiber for channeling light energy and a straightening tube circumscribing at least a portion of the optical fiber. The straightening tube is moveable between a first position and a second position. The tip assembly also includes a guiding member circumscribing the optical fiber and the straightening tube. The guiding member includes a curvable portion configurable between a pre-formed curved state and a straightened state, wherein, as the straightening tube is retracted from the first position to the second position, the guiding member transitions from its straightened state to its pre-formed curved state. An external surface of the straightening tube contacts an internal surface of the guiding member when the straightening tube is in the first position and the guiding member is in the straightened state.Type: ApplicationFiled: November 19, 2020Publication date: March 11, 2021Inventors: James C. Easley, Matt LaConte
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Publication number: 20210069016Abstract: A method of treatment is disclosed herein. The method includes administering to a patient in need thereof a biocompatible drug by at least one of intravenously, systemically, intravitreally, through the choroid, in the cerebrospinal fluid (CSF), topically, through the conjunctival mucosa, through the nasal mucosa, through the cornea, through the retinal optic nerve, through the nasal mucosa olfactory nerve, in the brain, in the spinal cord, the biocompatible drug comprising one or more cell pathway inhibitors together with one or more complement pathway inhibitors and/or one or more TGF beta inhibitors, the patient having one or more neurodegenerative disorders. The administration of the biocompatible drug to the patient treats the one or more neurodegenerative disorders, reduces the symptoms associated with the one or more neurodegenerative disorders, and/or alleviates the one or more neurodegenerative disorders.Type: ApplicationFiled: November 23, 2020Publication date: March 11, 2021Inventor: Gholam A. Peyman
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Publication number: 20210069017Abstract: An ophthalmic surgical instrument is provided that includes a handle having a handle distal end and a handle proximal end, a membrane removal instrument having an instrument proximal end attached to the handle distal end and an instrument distal end configured for engagement with an ophthalmic membrane, an aspiration port of the membrane removal instrument configured for engagement with at least a separated portion of the ophthalmic membrane with a suction force, and an aspiration lumen of the ophthalmic membrane removal instrument in operative communication with the aspiration port.Type: ApplicationFiled: September 4, 2020Publication date: March 11, 2021Inventors: Carl C. Awh, Scheller D. Gregg, Bass Eric, Niehoff Brad
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Publication number: 20210069018Abstract: Protective eyewear lens assemblies include one or more metal-detectable components and a lens body formed in-situ around the one or more metal-detectable components. The lens body is formed from a polymeric material such that the one or more metal-detectable component is permanently embedded within the lens body. Protective eyewear including such lens assemblies and methods of manufacture are also included.Type: ApplicationFiled: September 8, 2020Publication date: March 11, 2021Inventors: Bonnie K. San, Michael D. Love
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Publication number: 20210069019Abstract: Protective eyewear lens assemblies include one or more metal-detectable components and a lens body. The lens body is formed from a polymeric material and the one or more metal-detectable component are permanently encapsulated on, along or within the lens body. Protective eyewear including such lens assemblies and methods of manufacture are also included.Type: ApplicationFiled: September 8, 2020Publication date: March 11, 2021Inventors: Michael D. Love, Bonnie K. San
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Publication number: 20210069020Abstract: A visor that can be removably attached to a variety of field masks, including those used in softball and baseball and other sports, to protect the user from weather elements and minimize sun damage while not affecting play and withstanding movement. In some embodiments, the visor may include a curvilinear base having at least one recess. The visor may additionally include a brim attached to, or formed with, the base. The visor may further include a fastener received in the at least one recess, where the fastener is configured to secure the visor to the field mask.Type: ApplicationFiled: September 11, 2020Publication date: March 11, 2021Applicant: Z2D, LLCInventors: Joseph Hayes, Leslie Hayes
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Publication number: 20210069021Abstract: A dressing for use with percutaneous tubes/drains/pins and tracheostomies that is designed to be impermeable to aid in the prevention of leakage of body secretions or fluids and to help prevent microbes from entering the body around the percutaneous device from the outside of the dressing. The dressing includes three layers or more including a layer having antimicrobial, bacteriocidal, or hemostatic agents, a cushioned absorbent layer covered by an outer see through impermeable adhesive layer.Type: ApplicationFiled: September 4, 2020Publication date: March 11, 2021Inventors: Leslie Giesemann, Irene Rodriguez
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Publication number: 20210069022Abstract: Disclosed is a wound dressing material comprising a substrate, about 2.5% to about 8% by weight of a bicarbonate, and a film-forming agent, the film-forming agent serving as a binder for said bicarbonate to said substrate, the film-forming agent and the bicarbonate being present in a ratio of between 1:2 and 2:1 with respect to one another. Also disclosed are a method for preparing a wound dressing material and a method for treating a wound.Type: ApplicationFiled: November 11, 2020Publication date: March 11, 2021Inventors: Martin Coffey, Ramon Verduzco
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Publication number: 20210069023Abstract: A compression stocking having shape memory, heat-shrinkable thermoplastic material, wherein said stocking is configured to establish, in use, a compression contact with at least one of a leg and a foot of a user upon the application of an amount of heat to the shape memory, heat-shrinkable thermoplastic material, wherein the thermoplastic material is a polymer that has a glass transition temperature below ?10° C., has crystallinity with a melting temperature (Tm) between 30-50° C. and a heat of fusion of at least 10 J/g, as determined using differential scanning calorimetry (DSC) (?40° C./10.0 (K/min)/100° C.) as set out by the ASTM D3418:2003.Type: ApplicationFiled: December 11, 2018Publication date: March 11, 2021Inventors: Stefan HECTORS, Piet SMEETS, Jaap RENKEMA
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Publication number: 20210069024Abstract: A hemostasis device comprises a panel having a top side and a bottom side having an adhesive layer coupled to the panel. A button, having a 3-dimensional shape, is integrally molded to the top side of the panel. One or more apertures extend through the button and the panel. A pad joined to the panel by the adhesive layer. The button is engaged to a wound by a user and adapted to provide a force vector in a substantially axial direction to the wound. A method for imparting hemostasis comprises the steps of selecting an arterial pressure device then positioning the button with the one or more apertures over a wound. Retaining the device over the wound imparts a force vector in a substantially axial direction to the wound and results in more rapid blood coagulation.Type: ApplicationFiled: November 18, 2020Publication date: March 11, 2021Inventors: Barakat Alhammadin, Christopher Abboud
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Publication number: 20210069025Abstract: An apparatus for manufacturing an elastic composite structure includes a first roller configured to transport a web layer in a machine direction and a laydown guide configured to guide a laydown pattern of a plurality of elastic threads. A rotary anvil comprises a first weld line having a first notch formed in a contact surface of the first weld line, the first notch having a first interior configured to receive a portion of a first elastic thread of the plurality of elastic threads and a portion of the web layer therein. The first notch comprises a facing surface defining at least a portion of the first interior. A smallest orientation angle of a first face axis normal to the facing surface with respect to a contact surface axis normal to the contact surface is a first angle that is less than 90 degrees.Type: ApplicationFiled: August 17, 2020Publication date: March 11, 2021Inventor: Jeffrey W. Fritz
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Publication number: 20210069026Abstract: A method of applying elastic members includes applying a construction adhesive; intermittently applying an elastic adhesive; positioning first and second elastics in an elongated condition such that a first portion of the elastics are positioned in contact with both the construction adhesive and the elastic adhesive in hold zones and a second portion of the elastics are positioned in contact with the construction adhesive but not the elastic adhesive in release zones; severing the elastics in the release zones; retracting the elastics through the construction adhesive in the release zones; and maintaining the elongation of the elastics in the hold zones.Type: ApplicationFiled: November 17, 2020Publication date: March 11, 2021Inventors: Bradley W. Schoon, Chadwick I. Romzek, Erica F. Creighton
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Publication number: 20210069027Abstract: To enable an absorbent article to fit easily around the legs when worn and to improve fit. A pad which includes a polymer sheet having a superabsorbent polymer disposed between two nonwoven fabric sheets. Planar-shaped linear embossed grooves that protrude inward in a width direction from each side edge are formed at positions of the polymer sheet on which the groin of a wearer abuts when worn. Standing gathers BS that rise along a longitudinal direction on a skin side are formed on both side portions on the skin side. Regions that are surrounded by the embossed grooves tend to deform around the legs with the embossed grooves as flexible shafts, so that the polymer sheet fits easily around the legs when worn and fit is improved.Type: ApplicationFiled: March 28, 2019Publication date: March 11, 2021Applicant: DAIO PAPER CORPORATIONInventor: Tatsuhiko KASHIWAGI
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Publication number: 20210069028Abstract: An elastic laminate is provided including outer facing layers of a fabric and, located between the outer facing layers, a series of individual, spaced apart strips of elastic film extending continuously along the direction of elasticity. The film strips are formed by a controlled tearing of a continuous film while the film is biaxially stretched and bonded to the fabric facings. The fabric facings have gathers formed therein that allow the elastic laminate to stretch at least to the extent that the gathers can be pulled flat.Type: ApplicationFiled: February 28, 2018Publication date: March 11, 2021Inventors: Jose Augusto Vidal De Siqueira, Michael R. Vaughan