Patents Issued in April 8, 2021
  • Publication number: 20210100704
    Abstract: A standing-up assistance method and apparatus may measure a pressure applied to a part of a body of a user, acquire information about a torque corresponding to the measured pressure, and provide an assistance force to the body of the user based on the information about the torque.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 8, 2021
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventor: Kyung-Rock Kim
  • Publication number: 20210100705
    Abstract: A patient support apparatus comprises a support structure. The support structure comprises a base and a patient support deck coupled to the base. The patient support deck comprises a patient support surface capable of articulating to adjust positioning of a patient supported thereon, a lift system configured to adjust a height of the patient support deck relative to the base, and a user interface system coupled to the support structure and comprising an elongated member and a user interface coupled to the elongated member. The user interface is configured to receive inputs from a user to control a function of the patient support apparatus.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 8, 2021
    Applicant: Stryker Corporation
    Inventors: Anish Paul, Jeffrey S. Dunfee, II, Ryan Ross
  • Publication number: 20210100706
    Abstract: A patient support system comprises a patient support apparatus for patients. The patient support apparatus comprises a base and a patient support surface supported by the base. The patient support apparatus also comprises powered devices that perform one or more predetermined functions on the patient support apparatus. Multiple input devices are employed to control the powered devices. The input devices are designed to enable caregivers to cause operation of the powered devices, as needed, while freeing the caregivers to perform other tasks.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 8, 2021
    Applicant: Stryker Corporation
    Inventors: William D. Childs, Connor F. St. John, Brian J. Tessmer, Krishna S. Bhimavarapu
  • Publication number: 20210100707
    Abstract: Embodiments disclosed include devices for increasing bed (or sofa, chair, car-seat, etc.) mobility. Various embodiments are provided that may include a bed-strap, a fastening end, a hand-grip, and a pull-strap. Various embodiments of pull strap connector structures may provide types of engagements of the pull strap with a pull strap connector.
    Type: Application
    Filed: September 16, 2020
    Publication date: April 8, 2021
    Inventor: Toni Gay Davis Wolpe
  • Publication number: 20210100708
    Abstract: A modular insert for a patient room, the modular insert having a headwall with supply connections for electricity and medical grade vacuum, air and oxygen, and a lightbridge with medical examination lighting, the lightbridge coupled to the headwall. Further a lifting frame for transporting the modular insert to a patient room and facilitating installation thereof in the patient room, the lifting frame having a floor member for removably attaching to the headwall and a wall member for removably attaching to the lightbridge, the wall member pivotally attached to the floor member. Still further, a method for transporting the modular insert to a patient room and installing the modular insert in the patient room using the lifting frame.
    Type: Application
    Filed: October 5, 2020
    Publication date: April 8, 2021
    Inventors: Gunter Grant GEIGER, Patrick FENNINGHAM, Paul COUGHLIN, Samantha FOX, Greg SLODITSKIE
  • Publication number: 20210100709
    Abstract: A collection system for collecting outflow from a hysteroscopic surgical procedure includes a plurality of collection vessels each including a flexible body defining an internal volume and transitionable between a collapsed configuration and an expanded configuration. The collection system further includes connection tubing coupling adjacent collection vessels with one another, outflow tubing coupled to at least one of the collection vessels, and a plurality of retention canisters. Each retention canister includes a rigid body. Each collection vessel is configured to engage a corresponding retention canister such that each rigid body at least partially receives one of the flexible bodies therein.
    Type: Application
    Filed: October 4, 2019
    Publication date: April 8, 2021
    Inventors: NIKOLAI D. BEGG, ALLEN X. AN, DALIA LEIBOWITZ, TIMOTHY J. WOOD, JORDAN A. WHISLER, CHAD A. PICKERING
  • Publication number: 20210100710
    Abstract: Examples of a module for housing unrelated electronic and electromechanical equipment for use during surgery. The module can include a lower section and a tower-like upper section. The lower section can house unrelated electronic and electromechanical equipment. The tower-like upper section can be located on top of the lower section. A water-resistant cowling can enclose at least a portion of the lower section and the tower-like upper section. A cartridge containing one or more ultraviolet-C producing lights can be protectively housed within the tower-like upper section. The cartridge containing one or more ultraviolet-C producing lights can be configured to emerge upward from a top of the tower-like upper section to substantially seat itself on the top of the tower-like upper section when activated allowing the ultraviolet-C light to disinfect the patient and staff-contacting upper surfaces of the equipment in the operating room.
    Type: Application
    Filed: November 24, 2020
    Publication date: April 8, 2021
    Inventors: Scott D. Augustine, Susan D. Augustine, Garrett J. Augustine, Brent M. Augustine, Ryan S. Augustine, Randall C. Arnold
  • Publication number: 20210100711
    Abstract: Improvements in an inversion table leg restraint lock. The restrain has a primary and a secondary lock to restrain the ankles of a user to allow the user to invert their body while they lay on a table or bed. The primary lock is a rod connected to a pin. The knob can be easily accessible by a user when they “lean over” to grasp the arm. The telescoping tube is connected to a pin that that lifts a pin from a track. The secondary lock is deactivated when a user places pressure on the foot rest, as when a user stands onto the foot rest as they enter onto the inversion table. Both the primary and secondary locks must be deactivated to allow for movement between ankle restraining pads and a foot roller.
    Type: Application
    Filed: April 23, 2020
    Publication date: April 8, 2021
    Applicant: Paradigm Health and Wellness
    Inventors: Jackson Hsieh, Donrobert Pena
  • Publication number: 20210100712
    Abstract: A device for spine rehabilitation comprising a support frame, immovable crossbars, movable crossbars, and a holder and systems of actuators supporting a patient's head, shoulders, hip, knees, and feet , characterised in that it is equipped with linear actuators (8) mounted to the holder (7) supporting the patient's head and shoulders, whereby the holder (7) has a driving mechanism (9) situated horizontally and mounted to an immovable crossbar (6) of the support frame (1) and in its lower part is rotationally mounted, at the rotation point (10) of the holder, to the immovable crossbar (6). A method for spine rehabilitation using the device for lateral deviation of the patient's torso, whereby the patient's body situated horizontally, face up, is lifted on eight sling hangers taking hold of his/her head and his/her back in the points of shoulder girdle and pelvis girdle.
    Type: Application
    Filed: September 30, 2020
    Publication date: April 8, 2021
    Inventors: Jerzy KWASNIEWSKI, Szymon MOLSKI
  • Publication number: 20210100713
    Abstract: Mobility training apparatus 1 having a training means 2 for training muscles M and muscle fascia of the human body, wherein the training means 2 comprises at least one elongated training body 21, and is automatically movable up and down in a guide 3 by a drive in the vertical direction.
    Type: Application
    Filed: April 9, 2018
    Publication date: April 8, 2021
    Inventor: Murat Altinbas
  • Publication number: 20210100714
    Abstract: A dynamic foot plate assembly structured for therapeutic use adjacent the ankle area of the body comprising a base element, at least one side element extending along the ankle area, and at least one joint movably and adjustably connecting the base element to the side element for variable displacement of the base element and side element into different operative orientations. The dynamic foot plate assembly may also comprise a plurality of strut members disposed in an interconnecting relationship between either a support member and a side element, or the support member and the base element. The strut members, if present, facilitate the variable relative displacement of the base element, side element and support element into different operative orientations.
    Type: Application
    Filed: May 27, 2016
    Publication date: April 8, 2021
    Applicant: MDPO LLC
    Inventors: Luis E. Marin, Steve Ward
  • Publication number: 20210100715
    Abstract: A walking assistance method may include receiving at least one abnormal gait type selected from a plurality of abnormal gait types, and differently controlling a walking assistance apparatus based on the at least one abnormal gait type.
    Type: Application
    Filed: December 16, 2020
    Publication date: April 8, 2021
    Applicant: Samsung Electronics Co., Ltd.
    Inventors: Bokman LIM, Kyung-Rock KIM, Youngbo SHIM, Jusuk LEE, Jun-Won JANG
  • Publication number: 20210100716
    Abstract: An assistive pushcart device for rollerblading includes a set of first wheels and a set of second wheels that are rotationally coupled to a frame proximate to a front and a back of the frame, respectively. A handle that is coupled to and extends transversely from the back of the frame is configured to be grasped in one or two hands of a user to stabilize the user as the user locomotes the frame along a surface. Each of set of brakes is operationally coupled to a respective one of the first wheels and the second wheels. The set of brakes is positioned to selectively slow and stop rotation of at least one of the first wheels and the second wheels. An actuator that is coupled to the handle and operationally coupled to the set of brakes is positioned to selectively actuate the set of brakes.
    Type: Application
    Filed: October 3, 2019
    Publication date: April 8, 2021
    Inventor: Robert Farley
  • Publication number: 20210100717
    Abstract: A massage device is disclosed herein. The massage device includes a base assembly, the base assembly configured to be disposed on a support surface; at least one pole member configured to be coupled to the base assembly, the at least one pole member configured to extend upwardly from a top surface of the base assembly; and at least one massage head configured to be selectively coupled to the at least one pole member by a user, the selective coupling of the at least one massage head to the at least one pole member enabling the massage device to provide a massage to various parts of a user's body.
    Type: Application
    Filed: October 2, 2020
    Publication date: April 8, 2021
    Inventor: Cameron Beck
  • Publication number: 20210100718
    Abstract: A massage system includes a massage head configured to contact a treatment region of a patient during a massage treatment procedure, a body having a handle, a connector having a first end and a second end, wherein the first end is releasable secured to the body and the second end is coupled to the massage head, a motor positioned within the body and configured to drive movement of the massage head relative to the body, and a platform configured to be placed against the patient during a massage treatment procedure. The platform defines an opening. The platform is positioned so that the massage head extends at least partially through the opening during movement of the massage head relative to the body, and the platform surrounds the massage head in at least one dimension during movement of the massage head relative to the body.
    Type: Application
    Filed: October 19, 2020
    Publication date: April 8, 2021
    Inventors: Richard Loy Smith, JR., Mitchell Edmund Ziska, Jerry Douglas Leopold, James Alan Palma, JR.
  • Publication number: 20210100719
    Abstract: The present invention generally relates a multi-zonal and non-circular roller with several different zones along the periphery of the roller's outer surface and more specifically a roller having a non-circular internal area, a non-regular external surface covered by a series of multiple shape and angles designed to include to offer a user different types of resistance and muscle relief, including a point for the management of a myofascial trigger point.
    Type: Application
    Filed: October 3, 2019
    Publication date: April 8, 2021
    Applicant: Fitness Anywhere LLC
    Inventor: Mauricio Hernan DELGADO
  • Publication number: 20210100720
    Abstract: A system for supporting a spa shell may include a structural support paddle. The paddle may include a base portion and a paddle portion, connected to each other through an articulating joint such as a ball-and-socket. The top side of the paddle portion may include one or more pieces of cushioning material, such as EPF foam. The structural paddle assembly may be placed between the base of the spa and the spa shell. Typically 5 or more paddle assemblies are place in a spa for support, such as in the lowest areas of the spa shell and/or concavities, or convexities, of the spa shell. Compared to typical large blocks of foam used to support a spa shell from beneath, the structural support paddles provided increased room below the spa shell for ease of maintenance and installation, and more directly controlled support.
    Type: Application
    Filed: October 3, 2020
    Publication date: April 8, 2021
    Inventors: Nathan Tulett, Eric Hales, Creed Larsen, Robert Santos
  • Publication number: 20210100721
    Abstract: A blood storage container for the anaerobic storage of blood, having enhanced sealing methods and materials for the preservation of stored blood is provided.
    Type: Application
    Filed: October 16, 2020
    Publication date: April 8, 2021
    Applicant: Hemanext Inc.
    Inventors: Tatsuro YOSHIDA, Rafael CORDERO, Jancarlo SARITA, Michael ZOCCHI, Michael WOLF, Philip Michael KEEGAN, Narendran RENGANATHAN, Jeffrey Karl SUTTON
  • Publication number: 20210100722
    Abstract: A portable, versatile pill dispensing system can be used in a variety of settings and for a variety of pill dispensing regimens. Such systems and methods can be configured for intuitive filling or refilling, early or flexible dispensing, remote monitoring software to verify user compliance with a predetermined medication regimen, and features designed to improve compliance while traveling.
    Type: Application
    Filed: March 8, 2019
    Publication date: April 8, 2021
    Applicant: Dose Health, LLC
    Inventor: Paul Hines
  • Publication number: 20210100723
    Abstract: A pacifier for an individual, the pacifier including a shield, a handle extending from a first side of the shield, and a nipple extending from a second side of the shield. The handle defines a longitudinal axis and the nipple is inclined downwardly with respect to the longitudinal axis. A shelf connects the nipple to the shield. In different configurations the shelf includes varying widths and in other configurations the shelf width is different than a width of the nipple. A core extends from the handle, through the shield and into the nipple.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Inventor: Earl O. Bergersen
  • Publication number: 20210100724
    Abstract: The invention is a removable lid or cap which can be affixed to a disposable container such as a can or bottle in order to repurpose said container into a disposable spittoon. The invention comprises a tube which extends from the lid to the interior of the container to prevent spills. The invention further comprises a way to attach the lid to the container, including tabs or collar for interfacing with a can or bottle, respectively.
    Type: Application
    Filed: March 25, 2020
    Publication date: April 8, 2021
    Inventor: Devon Ross
  • Publication number: 20210100725
    Abstract: A topical cosmetic or medicinal formulation comprising strontium and methylsulfonylmethane (MSM) reduces irritation that may be caused by skin treatment compositions, especially low-pH skin treatments. strontium and methylsulfonylmethane may be provided with a dermatologically acceptable carrier as a separate composition, or may be provided with other active ingredients in a skin treatment formulation.
    Type: Application
    Filed: October 9, 2020
    Publication date: April 8, 2021
    Inventors: Eran ROSMAN, Masha MINKIN
  • Publication number: 20210100726
    Abstract: The present invention provides an anhydrous, sprayable sunscreen composition comprising one or more oil soluble UV filters and a combination of film formers comprising at least one copolymer of trimethylolpropane, adipic acid, neopentyl glycol and hexanediol and at least one acrylates/octylacrylamide copolymer having a molecular weight of at least 50 kDA measured using Dynamic Light Scattering.
    Type: Application
    Filed: October 4, 2019
    Publication date: April 8, 2021
    Inventors: Navya Mudya, Frank C. Sun
  • Publication number: 20210100727
    Abstract: Provided is a method for removing keratotic plugs capable of sufficiently exhibiting an excellent keratotic plug-removing effect without a burden, such as pain and of irritation, on the skin. The present invention relates to a method for removing keratotic plugs comprising using a composition comprising (X) one or more selected from the group consisting of (X1) 2-amino-2-hydroxymethyl-1,3-propanediol (X2), 2-amino-2-methyl-1-propanol, and (X3) 2-amino-2-methyl-1,3-propanediol.
    Type: Application
    Filed: April 9, 2018
    Publication date: April 8, 2021
    Applicant: KAO CORPORATION
    Inventors: Toshiaki OZAWA, Takaya SAKAI, Mariko MIYOSHI, Daisuke FURUKAWA, Aya SHIRAI
  • Publication number: 20210100728
    Abstract: The present invention relates to a pharmaceutical composition comprising piperonylic acid as an effective ingredient for anti-aging or regenerating the skin. A composition according to the present invention utilizes piperonylic acid that various plant species naturally contain therein and thus does not cause side effects. Piperonylic acid activates signals associated with cell survival, growth, and proliferation to exhibit the effect of increasing the resistance and survival of skin cells against external stimuli and enhancing the regeneration of the skin damaged due to external stimuli or senescence. In addition, piperonylic acid of the present invention has a similar function to EGF, but is stable and small in size in contrast to EGF. Thus, piperonylic acid of the present invention has the advantage of being able to easily move to the skin basal layer across the skin barrier and perform its function.
    Type: Application
    Filed: July 23, 2018
    Publication date: April 8, 2021
    Inventors: Kyong Tai KIM, Dohyun LEE, Jinsun LIM
  • Publication number: 20210100729
    Abstract: A fusion protein of heat shock proteins has an increased anti-oxidant activity and skin cell proliferation effect. An anti-wrinkle composition which has the fusion protein as an effective component can be advantageously used as a material of a functional cosmetic product. The fusion protein may be composed of heat shock protein 10 and heat shock protein 20. The fusion protein may include the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 4.
    Type: Application
    Filed: August 1, 2017
    Publication date: April 8, 2021
    Applicants: NEXGEN BIOTECHNOLOGIES, INC.
    Inventors: Sun Kyo LEE, Seong Ran LEE, Han Bong RYU, Tae Hyun KIM, Tae Won CHOI
  • Publication number: 20210100730
    Abstract: The present invention relates a powderous formulation comprising at least one fat-soluble vitamin, which can be produced easily and which can be used in many fields of application.
    Type: Application
    Filed: April 24, 2019
    Publication date: April 8, 2021
    Inventors: Andrea BULBARELLO, Stefanie KIRCHEN, Thomas LINDEMANN
  • Publication number: 20210100731
    Abstract: Disclosed herein is an oral hygiene composition comprising a styrene-maleic acid copolymer or terpolymer or salt thereof, wherein the copolymer or terpolymer or salt thereof has a polydispersity ranging from about 2 to about 14 and a minimum biofilm inhibitory concentration (MBIC) ranging from 0.001 ppm to 1000 ppm to reduce deposition of an oral biofilm on teeth or soft tissue. Also disclosed are processes for preparing a styrene-maleic acid copolymer or terpolymer or salt thereof.
    Type: Application
    Filed: May 24, 2019
    Publication date: April 8, 2021
    Applicant: ISP Investments LLC
    Inventors: Petros GEBRESELASSIE, Henry Keith CHENAULT, Yevgeniy TUROVSKIY, Karen WINKOWSKI
  • Publication number: 20210100732
    Abstract: An object to be solved by the present invention is to provide a composition for forming ?-gel which has a high stability with no color development or crystal deposition over time, and a ?-gel composition using the same. The ?-gel composition comprises: (A) 25 to 50% by mass of 1 or more higher aliphatic alcohols having 16 or more carbon atoms and/or higher fatty acids; (B) 40 to 70% by mass of specific polyoxyethylene sterol ether, and (C) 5 to 20% by mass of specific polyoxyethylene dialkyl ester and/or ether, and is generated by adding water.
    Type: Application
    Filed: January 6, 2017
    Publication date: April 8, 2021
    Applicant: SHISEIDO COMPANY, LTD.
    Inventors: REIJI MIYAHARA, Tetsuro YONEZAWA, Takashi OKA, Makoto UYAMA, Saori TANABE
  • Publication number: 20210100733
    Abstract: The present invention relates to avobenzone-dendrimer conjugates comprising: a polyamide dendrimer conjugated with 1 to 18 units of avobenzone. Also disclosed are sunscreen formulations comprising an avobenzone-dendrimer conjugate and a dermatologically acceptable vehicle.
    Type: Application
    Filed: March 8, 2019
    Publication date: April 8, 2021
    Inventors: Marcus WECK, Elizabeth Anne KAUFMAN
  • Publication number: 20210100734
    Abstract: The present invention provides a sunscreen composition comprising one or more oil soluble UV filters, at least about 20 weight percent ethanol, about 13.5 weight percent or less of a low viscosity silicone having a viscosity of at least 20 centistokes, and at least about 23 weight percent of a super low viscosity silicone having a viscosity up to about 15 centistokes, wherein the composition is anhydrous and transparent.
    Type: Application
    Filed: October 4, 2019
    Publication date: April 8, 2021
    Inventors: Elizabeth Maguyon, Frank C. Sun
  • Publication number: 20210100735
    Abstract: A deodorant stick comprising at least 25% by weight liquid triglyceride; a primary antimicrobial having a water solubility of at most about 90 g/L at 25° C.; a fragrance composition comprising at least about 50% natural oils, essential oils, or a combination thereof; and a primary structurant with a melting point of at least 50° C.; said deodorant stick being free of an aluminum salt; and said deodorant stick having a hardness from about 70 mm*10 to about 140 mm*10, as measured by penetration with ASTM D-1321 needle.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 8, 2021
    Inventors: David Arthur STURGIS, Lindsey Michelle BRITT
  • Publication number: 20210100736
    Abstract: The present invention relates to aseptic suspensions, physically stable and injectable through a 25 G needle or thinner, comprising crystalline, non-micronized 3-beta-hydroxy-5-alpha-pregnan-20-one particles, a mixture of acylglycerols and cholesterol, processes for preparing crystalline, non-micronized, 3-beta-hydroxy-5-alpha-pregnan-20-one suitable for such suspensions, as well as methods for manufacturing such suspensions.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Applicant: ASARINA PHARMA AB
    Inventors: Magnus Brisander, Karol Horvath, Björn Norrlind
  • Publication number: 20210100737
    Abstract: Provided is a transdermal drug delivery system comprising dronabinol. The dronabinol transdermal delivery system provides a drug plasma concentration at predetermined rate for a predetermined period of time, offering a simplified therapeutic regimen by decreasing dosing frequency for the treatment and/or prevention of nausea and/or vomiting associated with, for example, chemotherapy.
    Type: Application
    Filed: October 2, 2020
    Publication date: April 8, 2021
    Inventors: Fotios M. Plakogiannis, Tamanna Lather, Nisarg Modi, Marina Borovinskaya
  • Publication number: 20210100738
    Abstract: Disclosed are improved devices, systems and methods of delivering oxygen and/or other therapeutic substances to a living organism, such as a mammal and/or human patient, by delivering and/or circulating microbubble carriers within existing anatomical passages of the organism that are accessible via external body orifices, such as portions of the organism's digestive and/or excretory tracts.
    Type: Application
    Filed: October 13, 2020
    Publication date: April 8, 2021
    Inventors: Robert M. Scribner, Paul MOUNTFORD, Mark BORDEN, Robert T. Scribner
  • Publication number: 20210100739
    Abstract: The present invention relates to a novel pharmaceutical composition comprising doxycycline for topical application, in particular to the eye and eyelids. The invention also relates to this topical composition for use in the treatment of bacterial infections of the skin and mucous membranes.
    Type: Application
    Filed: April 3, 2018
    Publication date: April 8, 2021
    Inventors: Marion DUBALD, Sandrine BOURGEOIS, Hatem FESSI, Martine CLARET
  • Publication number: 20210100740
    Abstract: A medical device may comprise a body including a mixture of polyvinylpyrrolidone (“PVP”) and mitomycin. The medical device may be in any size or shape such that the medical device may be inserted into living tissue, including, but not limited to, a lacrimal punctual plug and a stent. The mixture of PVP and mitomycin may be coated on a portion of the medical device, contained within a cavity on the medical device, disposed on the surface of the medical device or configured as part of the medical device such that the mixture of PVP and mitomycin can be delivered to tissue.
    Type: Application
    Filed: October 2, 2019
    Publication date: April 8, 2021
    Inventors: Bruce Segal, Nelson Landrau
  • Publication number: 20210100741
    Abstract: A flavored bioactive extract may include a homogeneous flavored bioactive extract composition including a bioactive plant extract, flavoring, and a carrier. The carrier may be hydrophilic and the extract may have a crystalized or resinous form. The flavoring may be non-lipophilic or hydrophilic.
    Type: Application
    Filed: October 5, 2020
    Publication date: April 8, 2021
    Applicant: Pure Laboratories, LLC
    Inventor: Mark D. Keranen
  • Publication number: 20210100742
    Abstract: A new route is shown for antibiotic delivery in fighting drug resistant infections. Nanotubes and antibiotics and complexed non-covalently, with no chemical bonding, but through adsorption of antibiotics onto the nanotube surface governed by sufficiently strong molecular attraction between hydrophobic systems of the two. This allows the antibiotics to be freed from the nanotubes more easily as they reach the cell membrane. When antibiotics are introduced with nanotubes in this manner, bacterial resistance is mitigated by nanotube transport potentially into the membrane of the bacteria. Nanotubes used in this way help to overcome antibiotic resistance.
    Type: Application
    Filed: December 16, 2020
    Publication date: April 8, 2021
    Applicant: Texas Christian University
    Inventor: Anton V. Naumov
  • Publication number: 20210100743
    Abstract: The present invention involves novel urea compositions for oral administration, that are useful for treatment or management of hyponatremia. Also disclosed are novel methods of making the urea compositions.
    Type: Application
    Filed: October 5, 2020
    Publication date: April 8, 2021
    Inventors: Bhupinder Singh, Lee Souders
  • Publication number: 20210100744
    Abstract: Disclosed are compositions and methods for treating cancer with a hydrogel matrix comprising a chemotherapeutic agent and a blockade inhibitor. Disclosed herein are bioresponsive hydrogel matrixes comprising a reactive oxygen species scavenger.
    Type: Application
    Filed: May 13, 2019
    Publication date: April 8, 2021
    Inventor: Zhen Gu
  • Publication number: 20210100745
    Abstract: Provided are a liposome composition which has a practically required long-term preservation stability, and which has a release rate of a drug on the order of several tens of hours due to releasability of a drug being able to be suitably controlled by rendering an inner water phase hyper-osmotic; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which the content of cholesterols is 10 mol % to 35 mol % with respect to the total amount of lipid components in the liposome composition, and each of the liposomes encapsulates a drug in a dissolved state, and an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Applicant: FUJIFILM Corporation
    Inventors: Makoto ONO, Kohei ONO, Takeshi MATSUMOTO, Mikinaga MORI
  • Publication number: 20210100746
    Abstract: The embodiments disclose a method, including suspending cannabinoid compound molecules and constituents in an aqueous solution, suspending Aloe Vera molecules and its constituents in an aqueous solution, wherein a combination of cannabinoid compound molecules and constituents and Aloe Vera molecules and its constituents may be used for suspending in an aqueous solution, encapsulating cannabinoid compound molecules and Aloe Vera molecules within a liposome in an aqueous solution, and blending the liposome encapsulated cannabinoid compound molecules and Aloe Vera molecules with other ingredients into a health beneficial product and delivery system for oral including sublingual ingestion and nasal spray and suppository insertion or topical application with a plurality of nano sensors by humans.
    Type: Application
    Filed: October 6, 2019
    Publication date: April 8, 2021
    Inventors: Nicolas DeFrank, Antonio DeFrank, Edmond A. DeFrank
  • Publication number: 20210100747
    Abstract: Ground is a nutritional supplement designed to slow the negative effects of radiation on the body. It combines 4 natural compounds shown in clinical trials to reduce radiation-induced inflammation, into a single supplement.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Inventor: Tim Chrisman
  • Publication number: 20210100748
    Abstract: Launch is a nutritional supplement designed to slow the negative effects of radiation on the body while an individual is traveling in the upper atmosphere or outer space. It combines 5 natural compounds shown in clinical trials to reduce radiation-induced inflammation, into a single supplement.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Inventor: Tim Chrisman
  • Publication number: 20210100749
    Abstract: A composition for use in a method of providing sustained energy release over time in a subject is described. The composition comprises or consists of microparticles comprising high glycaemic index (Gl) carbohydrate contained within a gastric-resistant, ileal-sensitive, GLP-1 stimulative, non-porous carrier configured for release of the high Gl carbohydrate in the ileum, wherein the composition is administered orally to the subject.
    Type: Application
    Filed: March 7, 2019
    Publication date: April 8, 2021
    Inventors: Sinead Bleiel, Robert Kent, Neil Gerard Docherty, Carel Wynand Le Roux
  • Publication number: 20210100750
    Abstract: Therapeutic compositions deliver a therapeutic amount of methylphenidate in a delayed and extended release formulation. The dosage form exhibits a lag time prior to release of from 6 to 8 hours or longer, followed by a sustained release period.
    Type: Application
    Filed: December 16, 2020
    Publication date: April 8, 2021
    Inventors: David Lickrish, Feng Zhang
  • Publication number: 20210100751
    Abstract: The invention relates to a method of producing an emulsion or suspension from a biomass. The invention also relates to producing a powder or products produced therefrom. The invention also relates to an emulsion or suspension produced by a method as described herein. The invention also relates to a powder produced by a method as described herein or products produced therefrom.
    Type: Application
    Filed: February 1, 2019
    Publication date: April 8, 2021
    Inventors: Mary Ann AUGUSTIN, Luz SANGUANSRI
  • Publication number: 20210100752
    Abstract: Provided herein are methods and compositions for sensitizing a cancer cell to a cancer treatment, for example to an anticancer drug by the inhibition of at least two cancer biomarkers. Further provided are methods of treating and/or preventing a cancer including reducing the size of a tumor. Also provided are compositions comprising nanopartides associated with inhibitory molecules, such as siRNA, and/or anti-cancer drugs.
    Type: Application
    Filed: March 30, 2018
    Publication date: April 8, 2021
    Inventors: Raghuraman KANNAN, Dhananjay SURESH, Soumavo MUKHERJEE, Ajit P ZAMBRE, Anandhi UPENDRAN
  • Publication number: 20210100753
    Abstract: There is provided a method of preparing silica nanocapsules, the method comprising mixing a surfactant with water at a temperature that is above the gel-to-liquid transition temperature of the surfactant to form a mixture, passing the mixture one or more times through at least one pore to obtain a dispersion of vesicles, and adding a silica precursor to the dispersion of vesicles to form silica nanocapsules. Also provided is a silica nanocapsule formed from a vesicle template, and a method of delivering one or more types of molecules to a subject. In a specific embodiment, hollow silica nanocapsules having substantially lens-shaped are synthesized by employing dimethyldioctadecylammonium bromide (DODAB) or dioctadecyldimethyl ammonium chloride (DODAC) as the vesicle template and tetraethyl orthosilicate (TEOS) as the silica precursor.
    Type: Application
    Filed: March 28, 2018
    Publication date: April 8, 2021
    Inventors: Eun Ju PARK, Alexander M. VAN HERK, Praveen THONIYOT