Abstract: Systems and methods for delivery of fluid to a wound therapy dressing. In exemplary embodiments, a pressure sensor measures the pressure at the wound therapy dressing and restricts fluid flow to the wound therapy dressing when a predetermined pressure is achieve.

Abstract: A housing and flange assembly arrangement for a breast pump system including or involving a flange having transparent and other structure for facilitating alignment of the breast pump on a breast, and includes structure facilitating ease of assembly of a housing for the breast pump.

Abstract: The invention is a wearable breast pump system including a housing shaped at least in part to fit inside a bra and a piezo air-pump. The piezo air-pump is fitted in the housing and forms part of a closed loop system that drives a separate, deformable diaphragm to generate negative air pressure. The diaphragm is removably mounted on a breast shield.

Abstract: The invention is a wearable breast pump system including a housing shaped at least in part to fit inside a bra and a piezo air-pump. The piezo air-pump is fitted in the housing and forms part of a closed loop system that drives a separate, deformable diaphragm to generate negative air pressure. The diaphragm is removably mounted on a breast shield.

Abstract: The invention is a wearable breast pump system including a housing shaped at least in part to fit inside a bra and a piezo air-pump. The piezo air-pump is fitted in the housing and forms part of a closed loop system that drives a separate, deformable diaphragm to generate negative air pressure. The diaphragm is removably mounted on a breast shield.

Abstract: The invention is a wearable breast pump system including a housing shaped at least in part to fit inside a bra and a piezo air-pump. The piezo air-pump is fitted in the housing and forms part of a closed loop system that drives a separate, deformable diaphragm to generate negative air pressure. The diaphragm is removably mounted on a breast shield.

Abstract: The invention relates to a circuit arrangement for a protective-conductor connection to at least two fluid-conducting lines 11, 12, in particular to at least two fluid-conducting lines which are guided outwards from the interior of a housing 1 of a medico-technical device, in particular the housing of a blood treatment device. The circuit arrangement comprises a plurality of protection apparatuses 16A, 16B; 17A, 17B for electrical contacting which are designed such that an electrical connection to a fluid in the line can be produced using each protection apparatus for electrical contacting. In the circuit arrangement, at least two protection apparatuses 16A, 16B; 17A, 17B for electrical contacting are assigned to each fluid-conducting line 11, 12. As a result, two protective measures are taken for each fluid-conducting line.

Abstract: A system and apparatus for opening and emptying a bag of material includes a base having a pair of opposed sides and a central aperture through which material may flow. The system includes a pair of opposed doors rotatably mounted on a pair of door shafts, the edges of the pair of opposed doors forming an opening and a plurality of piercing blades pivotally mounted to the base on a pivot rod, the blades capable of pivoting to pierce said bag. The system further includes a cutting blade mounted transversely below the opening of the opposed doors, the cutting blade capable of linear motion across the opening.

Abstract: A system for monitoring percentage change in blood volume (?BV %) during dialysis treatment includes a sensor device configured to obtain hematocrit (Hct)-related measurements based on detecting light which has passed through extracorporeal blood of a patient undergoing the dialysis treatment; one or more controllers configured to: determine Hct values based on the Hct-related measurements obtained by the sensor device; determine ?BV % values based on the determined Hct values; and generate a GUI having a ?BV % plot based on the determined ?BV % values; and a display device having a display configured to display the GUI having the ?BV % plot. Zone indicators are provided on the display to distinguish between a first zone corresponding to a first ?BV % profile, a second zone corresponding to a second ?BV % profile, and a third zone corresponding to a third ?BV % profile.

Abstract: A patient fluid removal compensation volume may be determined to make up for the patient fluid removal that does not occur during machine down times, and the patient fluid removal rate may be increased until the compensating volume is satisfied.

Abstract: The present disclosure provides systems for controlling infusion of one or more supplements into blood received from a patient. The systems may include at least one extracorporeal circulatory support system including a pump, fluid conduits, and at least one sensor configured to measure one or more parameters of the blood. The system also may include a fluid flow regulator coupled to the extracorporeal circulatory support system; and a processor, a memory, and associated circuitry communicatively coupled to the at least one sensor and the at least one fluid flow regulator. The system receives measurement signals corresponding to parameters of blood from the at least one sensor and determines one or more target values for the parameters of blood based on a patient profile and/or the measurements. The system may control the fluid flow regulator to cause an infusion of at least one supplemental fluid from a supplemental fluid source into the blood.

Abstract: Treatment apparatus with liquid level controls for gas separation devices used to separate gas bubbles from liquids are described herein along with methods of controlling the level of liquids in the gas separation devices. The gas separation devices may be used in liquid treatment apparatus to separate gas bubbles from one or more liquids such as, e.g., physiological liquids (e.g., blood, etc.).

Abstract: A fluid injection device having a body contacting an injection site (SI); fluid reservoirs (210); an injection needle (120) that injects the contents of the reservoir(s) (210); and a respective priming needle (125) associated with each reservoir (210) for penetrating into the reservoir (210) before dispensing the fluid. Each reservoir (210) includes a tube (145) connected at one end to a priming needle (125), and at the other end to the injection needle. The device includes a reservoir selector for selecting one or more reservoirs (210), the contents of which are dispensed during the next actuation. The selector has a rotary member (132, 135) with a cam (1320, 1350) to co-operate with the tubes (145) so as to open or close the flow of fluid through each tube (145).

Abstract: Provided is an electroosmotic pump including a housing including a shaft hole, a membrane disposed between a first space arranged in a direction away from the shaft hole and a second space adjacent to the shaft hole, a first electrode body and a second electrode body arranged at opposite sides based on the membrane, a shaft extending to an outside of the housing through the shaft hole, and a first fluid included in an internal space of the housing.

Abstract: Ambulatory infusion pumps, pump assemblies, and baseplate assemblies, including cartridges, baseplates, cannulas, inserters, and related components and batteries therefor, as well as component combinations and related methods.

Abstract: A hollow puncture needle includes: a needle body portion; a needle distal end portion that extends from the needle body portion in a distal direction and that includes a blade surface that is inclined with respect to an axis of the puncture needle; and an ultrasonic wave reflecting structure including at least one reflecting portion having a concave or hole shape that opens on an inner peripheral surface of the needle distal end portion. An inner surface of the reflecting portion includes a pair of inclined surfaces that face each other, wherein a distance between the inclined surfaces becomes smaller in a direction towards an outer peripheral surface side of the needle distal end portion. The inclined surfaces is parallel to the axis of the puncture needle.

Abstract: A safety needle system includes a safety mechanism for a needle assembly, such as a Huber needle. A main body has a channel having a proximal end to encompass tubing and a distal end for positioning proximate a needle. The main body further has a first hinge mechanism and a first latching mechanism. A movable cover has needle receptacle, a second hinge mechanism connected with the first hinge mechanism of the main body, and a biasing member for pivoting movable cover about the first and second hinge mechanisms relative to the main body. The movable cover has a second latching mechanism to latch with the first latching mechanism in a closed position, in which the safety mechanism can be undocked from the needle and slid away from the needle along the tubing. The movable cover has a release mechanism to allow pivoting of the movable cover about the hinge mechanisms such that the needle receptacle of the movable cover at least partially receives the needle of the needle assembly in an open, locked position.

Abstract: Devices that are placed within fluid filled organs, such as the bladder, which reduce the risk of bacterial infections using a combination of active agents and mechanical disruption of bacteria.

Abstract: An autoinjector device and a method of use thereof for perispinal administration, comprising: a housing with an interspinous stop; a syringe assembly slidably mounted on the housing, the syringe assembly including a needle and a fluid container; an autoinjector actuator for urging the syringe assembly with respect to the housing from a storage position to a launch position wherein the needle travels through the interspinous stop; and a cap releasably engaged to the housing.

Abstract: The invention relates to an automatic drug delivery device (10), in particular automatic drug delivery device, for dispensing a fluid product, in particular a fluid medicament, including: a longitudinal housing (104) extending along a longitudinal axis and having a proximal end close to the dispensing site, a distal end opposite to the proximal end and a hollow interior; a removable cap (50) mountable to the proximal end of the housing (104); a syringe assembly (200) arranged a mounting position inside the housing (104) and having a hollow syringe body (204) and an injection needle (206) coupled to the hollow syringe body (204) including the fluid product; a drive mechanism (300) which can be triggered by a trigger element in order to initiate the dispensing of the fluid product; wherein the loaded drive mechanism is operatively coupled with a safety shield (102) movable within the longitudinal housing (104), wherein the safety shield (102) is biased into a proximal position in which it protrudes out of the p

Abstract: The present invention relates to a medicament delivery device comprising a housing (10), which housing is arranged to accommodate a medicament container (20); a power unit (88) comprising: a drive force element (98), an actuation unit (90, 102) operably connected to said drive force element (98); which actuation unit (90, 102) is movable, upon activation of said drive force element (98), for expelling a dose of medicament from said medicament container (20); a monitoring unit (130) provided with an electrical power source (140) for operating said monitoring unit (130). The invention is characterised in that the medicament delivery device further comprises an activation element (160) operably connected to said actuation unit (90, 102), to said monitoring unit (130) and to said electrical power source (140), wherein said activation element (160) is arranged to allow connection between said electrical power source (140) and said monitoring unit (130) when said actuation unit (98, 102) is moved.

Abstract: The present disclosure relates to a drug delivery device (10), comprising a housing (11) adapted to receive a primary package (24), the housing (11) comprising a distal surface (11.1) adapted to be placed against an injection site and a proximal surface (11.2) opposite the distal surface (11.1), the proximal surface (11.2) adapted to be held in the palm of a user's hand during drug delivery, the housing (11) having a flat form-factor in such a manner that a first extension of the housing (11) between the distal surface (11.1) and the proximal surface (11.2) is less than at least one extension at right angles to the first extension.

Abstract: The invention relates to an automatic drug delivery device (10), in particular automatic drug delivery device, for dispensing a fluid product, in particular a fluid medicament, including: •a longitudinal housing (104) •a removable cap (50) •a syringe assembly (200) •a drive mechanism (300) •wherein the loaded drive mechanism is operatively coupled with a safety shield (102) movable within the longitudinal housing (104), •wherein the safety shield (102) is biased into a proximal position in which it protrudes out of the proximal end of the longitudinal housing (104) in order to cover a needle tip (348) of the injection needle (206), and wherein the safety shield (104) is movable into a distal position in which the injection needle (206) is exposed for injection; •wherein the longitudinal housing provides an inner receiving component fixed thereto for receiving a syringe holder and providing a predetermined radial and axial position of the syringe holder within the longitudinal housing; •wherein the syringe ass

Abstract: The invention relates to an automatic drug delivery device (10), in particular automatic dmg delivery device, for dispensing a fluid product, in particular a fluid medicament, including: a longitudinal housing (104) extending along a longitudinal axis and having a proximal end close to the dispensing site, a distal end opposite to the proximal end and a hollow interior; a removable cap (50) mountable to the proximal end of the housing (104); a syringe assembly (200) arranged a mounting position inside the housing (104) and having a hollow syringe body (204) and an injection needle (206) coupled to the hollow syringe body (204) including the fluid product; a drive mechanism (300) which can be triggered by a trigger element in order to initiate the dispensing of the fluid product; wherein the loaded drive mechanism is operatively coupled with a safety shield (102) movable within the longitudinal housing (104), wherein the safety shield (102) is biased into a proximal position in which it protrudes out of the pr

Abstract: A needle-free injection system may include an active substance cartridge, which may have a nozzle and a plunger-actuated dosing chamber for the pressurized dispensing of an active substance. The injection device may have a housing with a receptacle for accommodating the active substance cartridge and a piston, which may be movable relative to the housing and may be designed to execute a movement for the ejection of the active substance from the active substance cartridge, where a mechanism for driving the plunger may be provided, and the plunger may have a starting position related to the mechanism, from which position the piston may be released to move by means of a trigger. The mechanism may be designed to allow the piston to return to the starting position. The dispensing quantity of the active substance may be adjustable.

Abstract: Injection device comprising a housing having an insertion opening at its distal end, a syringe carrier arranged within said housing, an actuation sleeve that is slidably arranged in the housing, first and second energy accumulating members, a plunger holder that is operationally associated with the first energy accumulating member and the syringe carrier, and a plunger rod that is slidably arranged in relation to plunger holder and to the syringe carrier, the plunger rod being operationally associated with the second energy accumulating member.

Abstract: A gasket includes a main body made of an elastic material, and a film laminated on the surface of the main body. The gasket has a film circumferential surface portion to be brought into contact with an inner peripheral surface of a syringe barrel, and an annular groove formed circumferentially of the film circumferential surface portion. The gasket further includes an annular member which is fixed in the annular groove and includes an annular projection projecting from the surface of the film.

Abstract: A method of assembling a drug delivery device, comprising the steps of: inserting a piston rod in a nut portion of a cartridge assembly and rotating the piston rod until the piston rod distal end engages the cartridge piston, mounting a drive member on the piston rod in a rota-tional position being closest to a pre-determined rotational position, and rotating the drive member to the pre-determined rotational position.

Abstract: The present invention relates to a drug-coated microneedle and a method of manufacturing the same, and more particularly to a drug-coated microneedle that delivers a drug by physically piercing the stratum corneum of the skin and a method of manufacturing the same. The drug-coated microneedle is represented by Chemical Formula 1 below, and is capable of releasing a drug through a redox reaction after penetration into the skin. The drug-coated microneedle according to the present invention is capable of effectively delivering a drug having excellent functionality but low skin permeability, and is thus useful as a material for functional cosmetics for whitening, wrinkle reduction, inflammation reduction and the like. [Chemical Formula 1] MN-S—S-D. In Chemical Formula 1, MN is a silica-(SiO2)-containing microneedle, S—S is a disulfide bond, and D is a drug.

Abstract: The invention relates to an automatic drug delivery device (10), in particular automatic drug delivery device, for dispensing a fluid product, in particular a fluid medicament, including: a longitudinal housing (104) extending along a longitudinal axis and having a proximal end close to the dispensing site, a distal end opposite to the proximal end and a hollow interior; a removable cap (50) mountable to the proximal end of the housing (104); a syringe assembly (200) arranged a mounting position inside the housing (104) and having a hollow syringe body (204) and an injection needle (206) coupled to the hollow syringe body (204) including the fluid product; a drive mechanism (300) which can be triggered by a trigger element in order to initiate the dispensing of the fluid product; wherein the loaded drive mechanism is operatively coupled with a safety shield (102) movable within the longitudinal housing (104), wherein the safety shield (102) is biased into a proximal position in which it protrudes out of the p

Abstract: The disclosure refers to a cap assembly for covering a needle shield of an injection device, the cap assembly comprising: a collar, and a cap with a sheath and a bottom, wherein the collar is movable along a longitudinal direction relative to the sheath from an unlocked position not engaging the sheath towards a locked position, force-lockingly engaging the sheath, thereby locking the sheath to the needle shield.

Abstract: Needle shield mechanism for an auto-injector comprising, a tubular housing (10), a needle shield (12) movably arranged in the housing (10), between a retracted state and an extended position, a releasable spring-biased container carrier assembly movably arranged relative to the housing (10) from an initial position to a penetrating position, wherein the container carrier assembly prevents the needle shield (12) from moving to the extended position when the container carrier assembly is in the initial position, and wherein the container carrier assembly allows the needle shield (12) to move to the extended position when the container carrier assembly is in the penetrating position.

Abstract: Apparatus, methods, and kits are for testing a catheter for an obstruction with a lumen by a medical practitioner at the point of use. In some embodiments, an elongate member, including elongate members comprising a gauge portion, is inserted into the lumen configured to detect a reduced diameter condition.

Abstract: The invention relates to a mixing channel for an inhalation device, and in particular to a mixing channel with improved injection and mixing properties for injecting and mixing a liquid drug into an air flow streaming in the mixing channel, thereby producing an aerosol to be inhaled by a patient. One aspect of the invention relates to a mixing channel for an inhalation device, comprising an inlet opening, an outlet opening, and an injection zone located between the inlet opening and the outlet opening, wherein the injection zone has a longitudinal center axis, wherein the injection zone comprises (a) a built-in nebulizer, or (b) a detachable nebulizer, or (c) a member adapted to receive a detachable nebulizer, wherein the effective cross sectional area of the mixing channel in a plane perpendicular to the longitudinal center axis is smaller in the injection zone than upstream of the injection zone.

Abstract: The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to an improved seal construction for an inhalation device having a nebulizing nozzle and a piston which moves relative to a pumping chamber in order to generate pumping pressure and to an inhalation device comprising such seal.

Abstract: A syringe-shaped spraying device includes: a barrel; a nozzle; a packing disposed therebetween; and a core disposed inside the nozzle. The nozzle is connected to a connecting portion provided at a front end of the barrel. The nozzle has a first facing surface facing a front end surface of the connecting portion and a second facing surface facing an outer circumferential surface of the connecting portion. The outer circumferential surface is provided with an annular recess portion, and the second facing surface is provided with a first annular protrusion portion and a second annular protrusion portion. By engaging the first annular protrusion portion with the annular recess portion, the packing is compressed in an axial direction by the front end surface and the first facing surface. The second annular protrusion portion is in pressure contact with the outer circumferential surface of the connecting portion entirely in a circumferential direction.

Abstract: A system and method for a salt holding integratable pillow having wool infused with different types of salts, particularly Pharmaceutical grade salt ground into a powder and essential oils that may be integrated into masks, scrubbing sleeves used by athletes and other people for performance, baby toys, cat toys for asthmatic felines, small pillows, pillow cases acting as a salt holding device, feed bag styles having salt holding devices for horses and other animals.

Abstract: There is disclosed an inhaler 10 for delivery of a medicament by inhalation. The inhaler 10 comprises a drive mechanism comprising a canister drive 22 for receiving a canister 50 of medicament, a biasing means 20, and a trigger mechanism. The trigger mechanism comprises a latch 35. The latch 35 has a locked position in which it contacts the canister drive 22 to prevent linear movement of the canister drive 22 and holds the biasing means 20 in a loaded configuration; and an unlocked position in which the latch 35 is disengaged from the canister drive 22 and releases the biasing means 20 from the loaded configuration to drive the canister drive 22 from a rest position to an actuated position. The trigger mechanism comprises a blocker 32.

Abstract: A delivery device for and method of delivering a dose of substance for systemic uptake to a nasal cavity of a subject, the delivery device comprising: a nosepiece unit for insertion into a nasal cavity of a subject and comprising an outlet unit which includes at least one nozzle for delivering substance for systemic uptake substantially only to surfaces in one or both of the anterior region and an anterior section of the posterior region of the nasal cavity of the subject; and a substance supply unit which is operable to deliver a dose of substance to the at least one nozzle.

Abstract: Sensing airflow and delivering therapeutic gas to a patient. At least some of the example embodiments are methods including: titrating a patient with therapeutic gas during a period of time when a flow state of breathing orifices is in a first state, the titrating results in a prescription titration volume; and then delivering the prescription titration volume of therapeutic gas to the patient when the flow state of the breathing orifices is in a second state different than the first state, the delivering only to the breathing orifices open to flow.

Abstract: A hypoxic training system is provided that dynamically adjusts the oxygen ratio in the gas provided to the user during a hypoxic training session based on the blood oxygen saturation (SPO2) level of the user. During a first training period, the hypoxic training system provides gas according to a first oxygen ratio. When it is determined that the SPO2 level of the user has reached a target SPO2 level, the hypoxic training system may provide a recovery period, during which gas according to a second oxygen ratio is provided to the user. When it is determined that the SPO2 level of the user has fallen more than a predetermined threshold below the target SPO2 level during the recovery period, the hypoxic training system may provide gas according to an increased first oxygen ratio during a subsequent training period.

Abstract: A fan unit that forms part of a gases supply unit used as part of a breathing assistance system for providing heated gases to a user. The fan has an impeller surrounded by an upwardly sloped surface to facilitate improved airflow performance under surge conditions.

Abstract: A respiratory device (10) includes at least one expiration valve (12) and/or at least one inspiration valve (14) with a valve drive (18) that is configured to influence a position of a closure element (20) of each valve (12, 14). A method for operating such a respiratory device (10) is also provided. The valve drive (18) acts on a valve chamber (24) and a volume in the valve chamber (24) determines the position of the closure element (20). The valve drive (18) includes a plurality of piezo pumps (40, 42), with at least one regular piezo pump (40) with a direction of action towards the valve chamber (24) and at least one inverse piezo pump (42) with a reverse direction of action.

Abstract: A system for delivering a flow of gas to an airway of a patient respiratory system includes a gas flow generator, a sensor, and a loop gain controller. The loop gain controller selectively controls the flow of gas to the airway according to a positive airway pressure (PAP) therapy mode. The loop gain controller comprises (a) a stability metric module, (b) a condition monitoring module that monitors ventilation characteristics of the flow of gas in the patient respiratory system and provides an output indicative of monitored ventilation characteristics, (c) a loop gain decision module that determines a future ventilation characteristic target and plant gain target, (d) a therapy prescription decision module that determines a therapy command pressure or delivery characteristic, and (e) a pressure delivery module that controls the gas flow generator to deliver the flow of gas at the determined therapy command pressure or delivery characteristic for a future breath.

Abstract: An artificial intelligence-based automatic intubation device according to an exemplary embodiment of the present invention includes: a body having, at one side, a video laryngoscope having an image capturing channel having a predetermined length, the body including a drive unit configured to move an intubation tube; a blade coupled to a circumference of the image capturing channel in a longitudinal direction of the image capturing channel, the blade being configured to be inserted into a trachea; and a control unit configured to control operations of the body and the blade so that the intubation tube is automatically introduced into the trachea.

Abstract: An integrated system for monitoring conditions of a patient and adjusting treatment for the patient based on comparisons of acquired data and historical data related to the patient includes a central processor, an oxygen concentrator, a level of consciousness monitor and a mobile device. The oxygen concentrator, the level of consciousness monitor and the mobile device are in communication with the central processor. The central processor includes a sleep database having baseline sleep information for a generic patient. The oxygen concentrator is configured to provide a flow of concentrated oxygen to the patient. The level of consciousness monitor is configured to collect data regarding the patient's state of wakefulness, awareness and alertness. The central processor collects data from the oxygen concentrator, the level of consciousness monitor and the mobile device and adjusts the oxygen concentrator based on comparisons of the baseline sleep information and the collected data.

Abstract: A fixing device in which the direction of a tube can be easily fine-adjusted is provided. A fixing device has: an arm portion which extends in the X direction; a fixation portion which is to fix a tube; and a rotation portion which is disposed between the arm portion and the fixation portion, and which rotates the fixation portion about the X direction.

Abstract: A pressure swing adsorption (PSA) system and methods for controlling each PSA cycle performed by the PSA system to produce oxygen enriched gas during productive portions of a user breathing cycle, and to cease production of oxygen enriched gas during non-productive portions of the user breathing cycle, is provided. The PSA system synchronizes PSA cycle phases including adsorption and desorption phases with a user's individual inhalation and exhalation phases, on a breath by breath basis, such that each PSA cycle can be dynamically varied from a succeeding PSA cycle, in real time in response to variations in the user's breathing cycle. An oxygen delivery device including a breathing cycle sensor provides breathing cycle inputs to a controller for use with at least one algorithm to detect breathing flow phases during each user breath, and to synchronize each PSA cycle to the user's breathing flow phases, on a breath-by-breath basis.

Abstract: A breathing assistance unit for providing pressurized heated humidified air to a user increases user compliance. The breathing assistance unit generates positive emotional and cognitive states of a user about the therapy.

Abstract: The present technology relates generally to cough-assist devices with humidified cough assistance. In one example, a system includes a cough-assist device having a first phase configured to provide insufflating gas to a patient circuit and a second phase configured to draw exsufflating gas from the patient circuit. A humidifier is disposed between the cough-assist device and a distal end of the patient circuit, the humidifier including a chamber configured to contain heated water and fluidically coupled to the cough-assist device and the patient circuit. The system further includes a bypass configured to (a) direct insufflating gas from the cough-assist device through a first route to the patient circuit such that the insufflating gas is humidified in the chamber, and (b) route exsufflating gas from the patient circuit through a second route to the cough-assist device such that the exsufflating gas bypasses the chamber.