Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a cord that is flexible and elongated defining a length. The cord may include a core having a porous surface and a porosity-reducing element on at least a portion of the core.

Abstract: A soft tissue repair device can include a housing having a handle, a deployment system having an actuation member, and an insertion system having an inserter and a slider. The slider can be coupled to the actuation member and movable relative to the inserter between deployed and retracted positions. First and second anchors can be carried on an external surface of the slider such that the anchors are spaced apart and portions of the anchors are coaxial with the slider and each other. A flexible strand can couple the anchors. The insertion system can cooperate with the deployment system to move the slider to the deployed position to deploy the first anchor upon activating the actuation member a first time, and to move the slider to the deployed position from the retracted position to deploy the second anchor upon actuating the actuation member a second time after the first time.

Abstract: A surgical instrument for stapling patient tissue is disclosed. The surgical instrument comprises an end effector, a firing element, an elongate shaft, a handle, an electric motor, and a display. The end effector extends from the elongate shaft and comprises a staple cartridge and a plurality of staples. The elongate shaft extends from the handle. The firing element is configured to move through the end effector between a proximal position and a distal position. The firing element is further configured to eject the plurality of staples from the staple cartridge during a firing stroke. The electric motor is configured to output a rotary motion and the firing element is operably responsive to the rotary motion. The display is configured to display a current position of the firing element during the firing stroke.

Abstract: A surgical instrument can comprise a handle including a battery cavity and electrical contacts and, in addition, a battery removably positionable in the battery cavity. The battery is configured to engage and supply power to the electrical contacts when the battery is operably seated in the battery cavity. The handle further comprises diagnostic means for assessing whether the handle is in a suitable operating condition and a battery lockout configured to permit the battery from being operably seated in the battery cavity if the diagnostic means determines that the handle is not in a suitable operating condition. Additionally or alternatively, the handle can comprise a battery lock configured to prevent the battery from being disengaged from the electrical contacts when the handle is transmitting an operating motion to a shaft assembly attached to the handle, for example. Either one system or two systems can comprise the battery lockout and battery lock.

Abstract: A surgical end effector configured for interchangeable use in connection with a hand-held surgical system and a robotically-controlled surgical system is disclosed. The surgical end effector comgrises a cartridge mounting gortion, a firing member, an anvil, and an end effector shaft assembly configured to be interchangeably attachable to a proximal shaft gortion grotruding from one of the hand-held surgical system or the robotically-controlled surgical system such that the surgical end effector is selectively articulatable relative to the groximal shaft gortion about multigle axes that are transverse to a shaft axis that is defined by the proximal shaft gortion.

Abstract: An exemplary surgical method includes possessing a loader that holds a curved-tip cartridge, and a surgical stapler that includes an anvil and channel at a distal end thereof; causing at least one of the loader and the channel to move toward the other; as a result of the causing, engaging the loader and the curved-tip cartridge with the channel; and causing at least one of the loader and the channel to move away from the other, such that the curved-tip cartridge remains engaged with the channel. That method further may include actuating the surgical stapler; grasping the unloader; sliding the unloader toward the channel; disengaging the curved-tip cartridge from the channel with the unloader; and withdrawing the unloader away from said channel, wherein the withdrawing causes the curved-tip cartridge to disengage from the channel.

Abstract: A surgical stapling device includes a housing assembly that is coupled to a tool assembly by a flexible elongate body that having an outer tube, a middle tube, and an inner cable. Each of the outer tube and the inner cable has a proximal end portion fixedly connected to the housing assembly and a distal end portion that is fixedly connected to the tool assembly. The middle tube is positioned within the outer tube about the inner cable and is movable from a retracted position to an advanced position to operate the tool assembly.

Abstract: The invention provides improved devices, systems, and methods for tissue approximation and repair at treatment sites. The invention provides devices, systems, and methods that may more successfully approximate and repair tissue by improving the capture of tissue into the devices. The invention may be a one-way mechanism that allows tissue to enter the mechanism but not easily exit, such as a leaf-spring, a protrusion, a pivoting arm and one or more frictional elements.

Abstract: An apparatus comprises a body, a shaft assembly, an end effector, a cartridge, and a staple driver actuator. The end effector is operable to manipulate tissue. The end effector comprises a lower jaw, a pivotable anvil, and a translating cutter. The translating cutter is operable to translate relative to the lower jaw and the anvil when the anvil is pivoted toward the lower jaw to manipulate tissue. The cartridge is insertable into the lower jaw and includes a plurality of staples. The staple driver actuator is disposed within the cartridge. The staple driver actuator comprises a secondary cutting element. The translating cutter of the end effector is operable to drive the staple driver actuator distally to staple and cut tissue substantially simultaneously.

Abstract: A device may include a shaft with a dispensing channel, an evacuating channel, a proximal end, and a distal end. The device may further include an enclosure attached to the distal portion of the shaft, the enclosure having a first portion and a second portion that form a bore when the enclosure is closed. The device may further include a handle attached to the proximal end of the shaft, which is configured to open and close the enclosure. A method of delivering a solution to a nerve repair site may include obtaining such a device, closing its enclosure around the nerve repair site, delivering one or more solutions through the dispensing channel to the nerve repair site, removing one or more solutions through the evacuating channel from the nerve repair site, and opening the enclosure to remove it from the nerve repair site.

Abstract: A method of adjusting a staple parameter of a surgical stapling instrument is disclosed. The method includes determining, by a control circuit of the surgical stapling instrument, a first stroke length for a first staple driver of the surgical stapling instrument to drive a first row of staples of a circular stapling head assembly of the surgical stapling instrument; detecting, by the control circuit, a malformed staple in the first row of staples; adjusting, by the control circuit, the staple parameter, based on the detection of the malformed staple; and determining, by the control circuit, a second stroke length for a second staple driver of the surgical stapling instrument to drive a second row of staples of the circular stapling head assembly.

Abstract: An implant for occluding a flow through a vessel may comprise a body member having a first end portion, a second end portion, and an intermediate rod portion extending between the first end portion and the second end portion and a mesh having base layer and a plurality of micro-pillars extending from a first surface of the base layer. The mesh may be disposed about at least a portion of the body such that the micro-pillars extending generally radially outward from the body member. The plurality of micro-pillars may be configured to extend into an adjacent tissue.

Abstract: The present invention relates in general to anchoring systems for occluder devices, and more specifically, to an anchoring system and method for implanting an occluder device within a left atrial appendage (“LAA”) of the heart. The anchoring system is configured so that an anchor penetrates the inner endocardium layer, middle myocardium layer, and outer epicardium layer of an LAA wall. The purpose of the present invention is to provide an occluder device anchor that has a low risk of embolization and/or causing injury to neighboring valve structures. An additional purpose of the present invention is to provide an anchoring system and method for implanting an occluder device within the LAA that allows for the occluder device to be retrievable after initial placement, reusable, and repositionable for an optimal final placement within the LAA.

Abstract: An embodiment of the invention is a shape memory polymer (SMP) foam designed to recover its original shape through exposure to a solvent. Thermo-responsive SMPs are polymers designed to maintain a programmed secondary shape until heated above their transition temperature, upon which the polymer recovers its original, or primary, shape. The thermo-responsive SMP foam is programmed to its secondary shape prior to use, typically compression of the foam to a small volume, and remains in this programmed shape until exposed to a selected solvent such as dimethyl sulfoxide or ethyl alcohol. Upon exposure to the solvent, the transition temperature of the SMP foam decreases below the temperature of the environment and the SMP foam actuates to its primary shape. The SMP foam is tailored to actuate upon exposure to specific solvents while minimizing or preventing actuation when exposed to water or other solvents.

Abstract: Controlled delivery of embolic beads into a subject's artery is achieved using a pump configured to draw fluid into a chamber and eject fluid from the chamber, one or more valves that control fluid-flow paths between three ports and the chamber of the pump, a valve actuator that places the one or more valves into various operating states, and a controller that controls the operation of the pump and the one or more valves in a controlled sequence. The various operating states interconnect one of the ports with a common port in fluid communication with the pump to achieve the controlled delivery of embolic beads.

Abstract: The present disclosure relates to a saw, comprising a drive, a first blade configured to oscillate about an axis perpendicular to a plane defined by a surface of the first blade, a second blade configured to oscillate about an axis perpendicular to the plane in a direction opposite to that of the first blade, and wherein gearing is provided between the drive and the first and second blades to reduce the speed transmitted from the drive to the blades. A saw blade, a connection mechanism for connecting a blade to a saw and associated methods are also provided.

Abstract: A surgical positioning system including a rotation guide slide and a rotation guide pointer configured to be coupled to the rotation guide slide. The rotation guide pointer includes a base and a pointer extension. The base includes protrusion and a hole extending through the base and the protrusion where the protrusion is sized and configured to be received within a channel such that the rotation guide pointer can translate parallel to a plane defined by the first side of the rotation guide slide. The hole is sized and configured to receive a screw to fix the position of the rotation guide pointer relative to the rotation guide slide, with the protrusion configured to expand when the screw is advanced in the hole.

Abstract: An orthopaedic surgical instrument includes a patella trial and drill guide that may be used to both perform a surgical trial of the patellofemoral joint and guide the surgeon in drilling a number of anchor holes in the patella of the patient. A method of using such an orthopaedic surgical instrument is also disclosed.

Abstract: A lithotripter is provided for fragmenting a stone inside a patient's body. In one form, the lithotripter includes a motor having at least two modes of operation and is configured to produce first and second waveforms. A wave guide shaft is configured to transmit the first and second waveforms to the stone. In one form, at least one of the first and second waveforms is provided to the stone at a frequency that is about equal to a natural frequency of the stone. In a variation, the lithotripter may include an ultrasonic driver configured to produce an ultrasonic frequency waveform and a sonic driver configured to produce a sonic frequency waveform. The sonic driver is mechanically coupled to the ultrasonic driver. The ultrasonic driver and the sonic driver may be disposed within a driver housing. In another variation, the lithotripter may include a brushless DC motor.

Abstract: A minimally invasive surgical assembly broadly includes an outer hollow needle which has an outer diameter of 3.0 mm or smaller, and a coaxial surgical instrument having a shaft which extends through the outer hollow needle. The coaxial surgical instrument includes end effectors at the end of the shaft which are biased to an open position such that when the end effectors of the surgical instrument extended out of the needle they open, and they are closed by relative movement of the needle over them. The assembly preferably includes a first fixing element which is used to fix the relative location of the surgical instrument and the needle. The assembly also preferably includes a second fixing element which moves relative to the needle and is located on the outside thereof and which is used to fix the relative location of the needle to the patient.

Abstract: A surgical treatment instrument includes a holdable housing, a shaft, an end effector configured to perform a bending movement with respect to the shaft, a rotor configured to rotate about a rotation axis in response to an operation input performed through an operation member, and a transmission member configured to transmit a driving force for causing the end effector to perform the bending movement to the end effector. The operation member and the transmission member are configured to rotate together with the shaft and the end effector in response to the operation input, and the rotor is configured to not rotate together with the shaft and the end effector when the operation input is performed.

Abstract: A treatment instrument includes a sheath having a longitudinal axis, an end effector provided on one end of the sheath, a housing to which the other end of the sheath is connected, and an operation dial provided to be rotatable relative to the housing around a first rotational axis. The operation dial includes a first outer peripheral surface provided around the first rotational axis, and a second outer peripheral surface spaced apart from the first outer peripheral surface in a direction along the first rotational axis and provided around the first rotational axis.

Abstract: A surgical clip applier is disclosed which is configured to automatically feed a clip from a clip cartridge once the surgical clip applier is positioned in the patient.

Abstract: A surgical instrument includes a hollow member having a sidewall provided with a window and a closure member movably connected to the hollow member for alternately covering and uncovering the window. The hollow member has a first clamping surface along an edge of the window, while the closure member has a second clamping surface opposing the first clamping surface and disposable substantially adjacent thereto in a clamping or closure configuration of the instrument. The instrument additionally comprises a tissue occlusion component mounted to at least one of the hollow member and the closure member for acting on tissues gripped between the first clamping surface and the second clamping surface, to couple the tissues to each other.

Abstract: An ultrasonic tip for fibrous tissue removal. The ultrasonic tip may be configured for at least torsional vibration and coupled to a distal end of a shaft of a surgical instrument with the shaft including a vibration conversion mechanism. The ultrasonic tip includes a plurality of slots extending between inner and outer circumferential surfaces to form a plurality of teeth. A depth of one of the slots at the outer circumferential surface is greater than a depth of the slot at the inner circumferential surface to define a sloped surface. The teeth include a cutting edge defined between the outer circumferential surface and a side surface defining the slot. The cutting edge includes a positive rake angle. The teeth may further include an inner cutting edge defined between the sloped surface and the inner circumferential surface with the inner cutting edge having a positive rake angle.

Abstract: Ultrasound oscillation can be propagated to a distal end of an elongated probe. A cross-sectional surface of the probe is perpendicular to the length of the probe, and has to the same shape as a shape of a cross-sectional surface of an anchor. The probe is configured to forma bottomed hole in a bone for placing the anchor and the shape of its cross-sectional surface can prevent rotation of the anchor in the bottomed hole. An area of the cross-sectional surface of the probe at the distal end can be larger than an area of a cross-sectional surface of the probe at a proximal end. The distal end of the probe includes a treatment portion that extends outward from a center of the proximal end of the probe in a first direction perpendicular to the longitudinal direction and in a second direction different from the first direction.

Abstract: Devices and methods for exploiting intramural (e.g., subintimal) space of a vascular wall to facilitate the treatment of vascular disease, particularly total occlusions. For example, the devices and methods disclosed herein may be used to visually define the vessel wall boundary, protect the vessel wall boundary from perforation, bypass an occlusion, and/or remove an occlusion.

Abstract: A catheter includes a catheter body (CB) having a CB proximal-portion, a CB distal-portion, and a CB lumen. The CB distal-portion has a CB distal end. The CB proximal-portion has a distally narrowing taper, wherein the CB distal-portion extends distally from the distally narrowing taper of the CB proximal-portion. The CB lumen extends through the CB proximal-portion and the CB distal-portion. An ultrasound transmission member (UTM) has a UTM distal end. The UTM extends longitudinally through the CB lumen. The UTM has a longitudinal taper that tapers toward the UTM distal end, and wherein the longitudinal taper tapers distally from the distally narrowing taper of the CB proximal-portion. A distal head (DH) is coupled with the UTM distal end and is disposed adjacent the CB distal end.

Abstract: Some implementations provide a tool that includes a gripping portion that includes a first substantially flat surface and a second substantially flat surface arranged substantially parallel to the first surface and coupled to the first surface by at least one side surface, wherein the gripping portion is shaped and sized such that a user can hold the gripping portion between a thumb and forefinger of the user; and a prying portion that includes a first end portion, a second end portion, and a shaft portion connecting the first end portion and the second end portion, wherein the first end portion is shaped and sized for the user holding the gripping portion to pry scab tissue away from a patient's skin and the second end portion is coupled to the gripping portion at the at least one side surface.

Abstract: A surgical knife safety device having a handle, a blade connected to the handle, and a guard carried by the handle for sliding movement between a retracted position in which the blade is exposed for use, and an extended position for covering the sharp cutting edge of the blade. A spring, such as leaf spring or a cantilever beam, and a pair of detents or slots are provided to fix the guard in the extended or retracted position and to provide resistance during movement between the two positions.

Abstract: Embodiments include devices and methods configured to fractionally resect skin and/or fat. Fractional resection is applied as a stand-alone procedure in anatomical areas that are off-limits to conventional plastic surgery due to the poor tradeoff between the visibility of the incisional scar and amount of enhancement obtained. Fractional resection is also applied as an adjunct to established plastic surgery procedures such as liposuction, and is employed to significantly reduce the length of incisions required for a particular application. The shortening of incisions has application in both the aesthetic and reconstructive realms of plastic surgery.

Abstract: A tissue splitting device for splitting a harvested soft tissue to provide a layer of tissue having a uniform thickness and methods for tissue transplantation using uniform layers of tissue.

Abstract: A double-sided needle groove, a frame body and a puncture frame, wherein the double-sided needle groove has an axisymmetric outer contour, and is provided at one side with at least one needle slot a (1) and at the other side with at least one needle slot b (2); and the needle slot b (2) is fan-shaped. The double-sided needle groove is provided with one or more needle slots a (1) having a fixed needle insertion angle and a needle slot b (2) having an adjustable needle insertion angle, and the needle slot a (1) and the needle slot b (2) respectively correspond to the diameters of puncture needles and may be designed to meet multiple width specifications. During the performance of a B-ultrasound puncture operation, based on operation requirements of a surgeon for a fixed or adjustable angle, there is only a need to switch front and back sides of the double-sided needle groove, thus avoiding the need for an additional puncture frame, and switch the needle slots according to the diameters of the puncture needles.

Abstract: A kyphoplasty cannula includes a shaft extending between opposite first and second end surfaces. The shaft has an inner surface defining a lumen. The shaft has a first opening that extends through the first end surface and a second opening that extends through the second end surface. A scoop extends from the second end surface. The scoop has an arcuate inner surface that is continuous with the inner surface of the shaft an opposite outer surface. The scoop has a rib. Kits and methods of use are disclosed.

Abstract: Method and apparatuses for providing access to a body cavity of a living animal through an access port inserted in an incision made in a wall of the body cavity are disclosed. In some embodiments, the apparatus includes a cap configured to attach to the access port, the cap including an opening configured to permit insertion of a medical instrument through the cap and access port into the body cavity, and a tubular sleeve including a distal end sealingly connected at the opening and extending outwardly therefrom, the sleeve including a proximal end configured to receive and provide a seal with the medical instrument when received. The apparatus also includes a closure disposed to temporarily seal the sleeve prior to insertion of the medical instrument through the opening in the cap.

Abstract: The present invention comprises systems, methods and devices for the delivery of compositions for occluding or of means for opening conduits. The implantable occlusive material may be delivered pre-formed or in situ cured and, may be a resorbable material that supports tissue ingrowth that eventually replaces the material leaving little or no original material in place. The delivery system is positioned to allow for placement of the occlusive material into the body conduit. Use of delivery systems, methods and devices for re-opening an occluded body conduit are also included.

Abstract: A bone anchor includes a shank for anchoring to a bone and a receiving part for coupling a rod to the shank. The receiving part includes a base and two legs each including a first portion extending away from the base, and a second portion extending from the first portion further away from the base, and an elongate extension member extending from the second portion still further away from the base. An internal engagement structure is provided on the first and second portions for engaging a fixation device. A breakaway portion facilitates breaking away of the second portion. The extension members are at least as long as the second portions. The second portions are stiffer than a region of the extension members adjacent the second portions.

Abstract: Provided are improved pedicle screws or lateral mass screws, systems and methods for stabilizing spinal vertebrae, such as a pedicle or lateral vertebral mass, during minimally invasive spinal surgery. For example, provided is a pedicle screw or lateral mass screw having a screw shaft comprising an elongated threaded body having a vertical axis, a polyaxial screw head comprising two opposite walls that define a concave channel, and two semi-rigid, non-wire, elongated projections extending from two opposite walls of the polyaxial screw head at a positive angle in relation to a horizontal plane.

Abstract: A spinal construct comprises a fastener including a head. A member includes an inner surface defining a cavity configured for disposal of the head and a groove configured for disposal of a band that is engageable with the head to connect the fastener and the member. The member includes a transverse rod. A coupling member is engageable with the inner surface. Implants, systems, instruments and methods are disclosed.

Abstract: A pivotal uniplanar bone anchor assembly includes a shank having a shank head with a partial spherical shape at a proximal end and an anchor portion opposite the shank head for fixation to the bone of a patient. The assembly also includes a receiver having a top portion defining an open channel for receiving an elongate rod and a base defining a cavity in communication with the open channel and with a bottom surface of the receiver through a distal opening. The assembly further includes a retainer positionable into non-pivotal engagement with an inner surface of the cavity prior to the shank head being received within the cavity, with the retainer having a central passage configured to receive and support the shank head within the cavity while restricting pivotal motion between the shank and the receiver to a single plane.

Abstract: An expandable facet joint fixation device, including a first collar, a central shaft including a first end and a second end, the first end rotatably connected to the first collar, a second collar including a radially inward facing surface, the second collar concentrically arranged around the central shaft, and one or more expandable members, each of the one or more expandable members including a first arm hingedly connected to the first collar, a second arm hingedly connected to the second collar, the second arm hingedly connected to the first arm, wherein when the second collar is displaced in a first axial direction relative to the first collar, the one or more expandable members displace radially outward in a first radial direction.

Abstract: A method of repairing a pars fracture includes docking a needle guide on a lamina of the pars, inserting a needle at least partially through the needle guide, inserting a stylet at least partially through the needle, inserting a guidewire at least partially through the needle, removing the needle from the needle guide, removing the needle guide, positioning a screw assembly in contact with the lamina and co-axially with the guidewire, rotating an elongated portion of the screw assembly with respect to the lamina to move the screw assembly distally with respect to the lamina such that a distal end of the elongated portion of the screw assembly travels through an interior portion of the pars and into a superior portion of the pars, and approximating the distal end of the elongated portion of the screw assembly and a collar of the screw assembly to approximate the interior portion of the pars and the superior portion of the pars.

Abstract: A medical inserting apparatus includes a screw nail which is inserted into a human body, a driver which inserts the screw nail into the human body, a current generator disposed in the driver to generate a predetermined current, a current meter disposed in the driver to measure the current, and a conductor element disposed in the screw nail and the driver along a lengthwise direction including an exposed portion to outside, wherein the conductor element includes a forward conductor element connected to the current generator to allow the current generated by the current generator to flow into the human body, and a reverse conductor element having one end electrically connected to the forward conductor element and the other end connected to the current generator, and including a variable resistor and the current meter installed to allow the current generated by the current generator to flow to the current meter by current division with resistance of the human body.

Abstract: An extramedullary compression and fixation apparatus consists of a pre-curved, malleable band having a first end and a second end, and at least one bone engaging structure protruding from the band toward an interior space defined by the band. The band is configured to be compressed (e.g., crimped) over a bone fracture site to conform the curvature of the band to a curvature of a surface of bone around the bone fracture site. The at least one bone engaging structure is configured to dig into the outer cortex of the bone when the band is compressed. The band is configured to maintain compression of the bone across the bone fracture upon the band being compressed without additional external fixation devices.

Abstract: A quick release sternum closing fixator has a locking roller, and a male fixing piece and a female fixing piece that can be plugged together. The male fixing piece has an elastic plug and the first claw hook plate. The elastic plug has the first serration on both sides and a tightening groove in the middle, thus forming two elastic claws. A tensioning device forces the two elastic claws to move against each other is provided between the said locking roller and the two elastic claws. After the locking roller rotates, when the elastic claws on the male fixing piece lose resilience due to the growth of human tissues, the two elastic claws can be forcibly pulled back to the initial state by rotating the locking roller, thus smoothly and quickly opening the sternum closing fixator.

Abstract: Bone fixation systems include various combinations of stabilizing members, dynamic elements, fasteners, and locking mechanisms. Bone plates receive dynamic bone staples and bone screws. Other dynamic elements include elbow pegs, straight pegs, and wire pegs.

Abstract: A cannulated nail extractor including an extractor having a proximal end for connecting to an extraction device, a distal end opposite the proximal end, and a connector extending from the distal end. The cannulated nail extractor further includes an engagement wire having an enlarged proximal end configured to engage the extractor and an enlarged distal end configured to engage a distal end of the cannulated nail. The cannulated nail extractor further includes a positioning wire for insertion into the cannulated nail for urging the enlarged distal end of the engagement wire into engagement with the distal end of the cannulated nail, whereby exerting an extraction force on the extractor produces extraction force by engagement of the enlarged distal end of the engagement wire on the distally facing end of the cannulated nail.

Abstract: Systems and methods for indicating an interval in which a procedure (or sub-procedure) should be carried out are disclosed. Some systems and methods involve timing various sub-procedures and alerting a practitioner at the completion of a sub-procedure period. Some systems and methods include a sensor, such as a temperature sensor, that is used determine a window of time in which a variable-viscosity material is of suitable viscosity for delivery to a patient.

Abstract: A bone cement applicator comprising a cartridge with an internal space. The cartridge has a head with a dispensing opening for expulsion of bone cement, a first thread, a dispensing plunger, a threaded tube having a counter thread engaging the first thread, a receptacle mobile in the threaded tube, and a mixing rod with a mixer fastened to it and arranged in the internal space of the cartridge. The mixing rod is detachably connected to the receptacle and is guided through a feedthrough in the dispensing plunger and is supported in the feedthrough so as to be axially mobile. When detached from the receptacle, the mixing rod can be pushed into the receptacle when the receptacle is propelled in the direction of the cartridge head. A method is also disclosed for production of a bone cement using the bone cement applicator.

Abstract: A bone cement applicator comprising a cartridge with an internal space. The cartridge has a head with a dispensing opening for expulsion of bone cement, a dispensing plunger, a receptacle mobile in the cartridge, and a mixing rod with a mixer fastened to it and arranged in the internal space of the cartridge. The mixing rod is detachably connected, on a side opposite from the mixer, to a front side of the receptacle that faces the cartridge head. When the mixing rod is detached from the receptacle and the receptacle is propelled in the direction of the cartridge head the mixing rod can be pushed into the receptacle. A method is also disclosed for production of a bone cement using the bone cement applicator.