Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The software and interchangeable auxiliary hardware system for remote telemetric diagnostics of the physiological and mental state of a subject that includes an electronic computing device of a subject with a camera operably configured to measure spectroscopic changes, parameters of discoloration in the skin and the mucous membrane tissues in the areas of the subject's face, to provide assessment of pupils and sclera pigmentation, coupled with multiple interchangeable sensors to assess a surface temperature of the skin, composition of exhaled air from the subject, sensorimotor reaction of the subject, motor activity of the subject, and optical lighting operably configured to assess skin color and perfusion of blood vessels of the subject's face remotely; the electronic computing device of the subject communicatively coupled to a processor, operably configured through programed software instructions, to process the registered data and transmit it to a medical practitioner's personal computer to conclude with a

Abstract: A wireless patient monitoring system includes at least one wireless physiological sensor having a sensing element senses physiological parameter information from a patient. A sensor controller is configured to determine a current parameter value based on the physiological parameter information and to compare the current parameter value to a prior parameter value. Based on the comparison, the sensor controller determines if the current parameter value is redundant of the prior parameter value. If so, then the current parameter value is not transmitted. If the current parameter is not redundant of the prior parameter value, then a wireless transmitter is controlled to wirelessly transmit the current parameter value.

Abstract: Particular embodiments described herein provide for an apparatus to determine biometric data of a user including: a processing circuit configured to: generate a control signal relating to a control value for controlling a wavelength of emitted light of a light source; receive biometric input data based on reflected light from the skin of the user caused by the light of the wavelength emitted by the light source; and determine biometric data of the user based on the biometric input data; and an output interface configured to provide the biometric data of the user.

Abstract: The present disclosure provides a system for interrogating tissue comprising a light source for illuminating tissue comprising lesions from ablation and a sensor being configured to receive light to detect autofluorescence from the illuminated tissue. The sensor detects light at a first wavelength in a first wavelength range such that the first wavelength range includes a peak intensity of autofluorescence from the illuminated tissue and detecting light at a second wavelength in a second wavelength range such that the second wavelength range is 20 nm-100 nm longer than the first wavelength range. A processor is programmed to generate a first digital representation of the tissue from light detected in the first wavelength range and a second digital representation of the tissue from light detected in the second wavelength range, and generate a final digital representation from the first and second digital representations. The final digital representation distinguishes between ablated and non-ablated tissue.

Abstract: A spectroscopic system may include: a probe having a probe tip and an optical coupler, the optical coupler including an emitting fiber group and first and second receiving fiber groups, each fiber group having a first end and a second end, wherein the first ends of the fiber groups are formed into a bundle and optically exposed through the probe tip; a light source optically coupled to the second end of the emitting fiber group, the light source emitting light in at least a first waveband and a second waveband, the second waveband being different from the first waveband; a first spectrometer optically coupled to the second end of the first receiving fiber group and configured to process light in the first waveband; and a second spectrometer optically coupled to the second end of the second receiving fiber group and configured to process light in the second waveband.

Abstract: A dental probe for determining the vitality of a tooth, comprising a light emitter and a light receiver, wherein the light emitter emits light from an emitter surface adapted to be positioned on a hard dental surface of a tooth, wherein the light receiver collects light incident on a receiver surface adapted to be positioned on a hard dental surface of the tooth so that the optical path of the light emitted from the light emitter passes at least through a portion of the pulp chamber of the tooth. The light receiver includes a light shielding spacer member adjacent to the optical path for establishing and maintaining a distance of at least 50 ?m between the gum line and the optical path at the receiver surface.

Abstract: Provided are an ultrasound imaging apparatus and a surgical operation support system for obtaining position information of a device outside an imaging area and presenting the position information to a user together with an ultrasound image. The surgical operation support system includes the ultrasound imaging apparatus, an ultrasonic source fixed to a therapeutic tool to be inserted into a subject body, a display device for displaying the ultrasound image and the position of the ultrasonic source. The ultrasound imaging apparatus is provided with a position estimator for estimating the position information of the ultrasonic source, and the position estimator analyzes a grating lobe artifact (false image) that is generated by the ultrasonic wave emitted from the ultrasonic source outside the imaging area, to estimate the position information of the ultrasonic source with respect to the imaging area.

Abstract: A screening method includes controlling a heat source of a screening device to reach a selected temperature, determining a location of a subject, and determining that the location is a desired distance from the screening device. The method also includes based at least in part on determining that the location is the desired distance from the screening device, simultaneously determining a temperature of the subject and a temperature of the heat source using a temperature sensor of the screening device.

Abstract: A system and method are provided to deploy an implant assembly in a vessel. The implant assembly comprises a pressure sensor having a body, and first and second anchoring members coupled to the body of the pressure sensor. A delivery apparatus comprises a shaft having proximal and distal ends, the shaft including a main lumen and a secondary lumen, the main lumen extending along at least a portion of the shaft. The secondary lumen extends along at least a portion of the length of the shaft, the secondary lumen joined with first and second ports provided in a sidewall of the shaft. A tether wire is configured to be slidably positioned within the secondary lumen, the tether wire having a distal portion configured to secure the implant assembly against the sidewall.

Abstract: A system for measuring capillary refill time includes a wearable device and a control unit. The wearable device includes a force sensor to obtain a force signal and an optical sensor to obtain an optical signal. The system ensures that an applied force is acceptable in both magnitude and duration, and that a duration over which the applied force is released or removed is acceptable. These factors can establish that a capillary refill time determined or calculated therein is accurate. The system can also determine the capillary refill time based on the force and optical signals obtained by the force and optical sensors, respectively.

Abstract: A wireless patient monitoring system includes a host device configured to pair with one or more wireless physiological sensors to receive physiological data therefrom. The host device includes a nearfield communication (NFC) transmitter emitting an electromagnetic field. The system includes at least one wireless physiological sensor having a sensing element that senses physiological parameter information from a patient, a battery, and a field detection circuit configured to detect NFC field and to generate an activation signal thereupon. A sensor controller is configured to operate in a sleep state that maximizes battery power consumption by the wireless physiological sensor and to receive the activation signal from the field detection circuit when the NFC field is detected. After receipt of the activation signal, the sensor controller operates the wireless physiological sensor in an activated mode that enables full power consumption by the wireless physiological sensor.

Abstract: There is disclosed a vital sign measuring device (VSMD) for obtaining an indication of a person's blood pressure via the person's finger by means of a finger cuff having an inflatable bladder. Blood pressure may be determined without the use of any electromagnetic radiation, such as miniature dynamic light sensing (mDLS). Apparatuses and methods for obtaining an indication of other vital signs, including hematocrit and total protein, are also disclosed.

Abstract: A system includes a minimally intrusive display system (MIDS) configured to be disposed on an eyewear. The MIDS includes a display system and a sensor system configured to provide for a sensor data. The MIDS further includes a processor configured to download a workout and to process the sensor data to monitor a user wearing the MIDS during the workout. The processor is further configured to display, via the display system, a workout progress based on the monitoring.

Abstract: Disclosed are devices and methods for non-invasively measuring arterial stiffness using pulse wave analysis of photoplethysmogram data. In some implementations, wearable biometric monitoring devices provided herein for measuring arterial stiffness have the ability to automatically and intelligently obtain PPG data under suitable conditions while the user is engaged in activities or exercises. In some implementations, wearable biometric monitoring devices are provided herein with the ability to remove PPG data variance caused by factors unrelated to arterial stiffness. In some implementations, wearable biometric monitoring devices have the ability to perform PWA while accounting for the user's activities, conditions, or status.

Abstract: Central blood pressure parameters are monitored using a smart watch or smart band. A PPG sensor on the smart watch or smart band is adapted to sense blood perfusion in the finger (or lower wrist/radial artery) of the person wearing the smart watch or smart band. The PPG signal captures cardiovascular features which can be detected after proper filtering and processing. Signal processing, using the transfer function method, results in an un-calibrated central pressure waveform, which can be used to calculate various cardiovascular parameters or indicators of the parameters that are displayed on the smart watch or smart band. Digital signal processing can be implemented on the smart watch or smart band, on a smart phone, laptop or in the Cloud.

Abstract: The present disclosure generally relates to user interfaces for health applications. In some embodiments, exemplary user interfaces for managing health and safety features on an electronic device are described. In some embodiments, exemplary user interfaces for managing the setup of a health feature on an electronic device are described. In some embodiments, exemplary user interfaces for managing background health measurements on an electronic device are described. In some embodiments, exemplary user interfaces for managing a biometric measurement taken using an electronic device are described. In some embodiments, exemplary user interfaces for providing results for captured health information on an electronic device are described. In some embodiments, exemplary user interfaces for managing background health measurements on an electronic device are described.

Abstract: An electrocardiogram information dynamic monitoring method and dynamic monitoring system.

Abstract: Examples presented herein generally include systems and methods which can contact electrodes to cardiac tissue while sensing electrical potential from fluids near the tissue. The electrodes in contact with the tissue can be carried by an end effector and can be used to sense and/or ablate the tissue they contact. A reference electrode can be insulated by a shaft connected to the end effector so that the reference electrode can sense the electrical potentials from the fluids near the tissue while being prevented, by the shaft geometry, from contacting the cardiac tissue. In some examples, the reference electrode can be tubular, having an inner surface that is configured to contact and sense electrical potentials from the fluids and an electrically insulated outer surface. Configured as such, the reference electrode can serve as an extension of an irrigation tube extending through the shaft.

Abstract: Aspects of the invention are directed to coil positioning apparatuses, systems, and methods of employing the same. One portable head coil apparatus is provided for use with a magnetic resonance imaging system. The portable head coil apparatus includes a base having at least one coil array comprising at least two coil elements. The base is positionable relative to the patients head and has a receiving portion defining a receiving surface positionable adjacent the patient positioning device. The portable head coil apparatus includes an extension movable relative to the base and having at least one coil array comprising at least two coil elements. The extension defines an inner surface having a curvature the degree of which is greater than that of the receiving surface of the base. The inner surface of the extension and the receiving surface of the base together at least partially define an imaging region therebetween.

Abstract: A meridian impedance measurement device and method are provided, including: at least one set of measurement electrodes placed on the wrists or ankles, each set including six measurement electrodes in contact with six corresponding meridians; at least one reference electrode placed on the wrists or ankles, simultaneously being in contact with all the six corresponding meridians; at least one impedance measurement unit; a microprocessor; an impedance display unit; and a storage unit. During measurement, the adjustable voltage output unit delivers voltage to each pair of measurement electrode and reference electrode, the impedance measurement unit collects signals and pass the signals to the microprocessor for calculation. The whole procedure is done automatically and can be built into a wearable device.

Abstract: An apparatus for measuring impedance is provided. The apparatus may include an electrode part in which a plurality of electrodes are arranged; a depth controller configured to configure electrode clusters from among the plurality of electrodes of the electrode part based on a measurement depth of the object, and generate a control signal; a switch configured to connect electrodes in the electrode clusters to signal lines based on the control signal; and a measurer configured to measure the impedance of the object based on signals measured through the electrode clusters.

Abstract: A system and method using a microphone to collect sound data produced by a potential patient's respiration and speech. The system preferably uses a microphone on a portable electronic device—such as a smart phone. The analysis of the collected data is preferably performed locally—such as by a software application running on the smartphone. The software is used to analyze the data and therefore determine and track useful parameters such as respiration rate and respiratory tidal volume. The software also analyzes phonation patterns. Using the parameters, the inventive system can detect the onset of respiratory distress.

Abstract: A breathing monitor that includes a contactless sensor that uses magneto-LC resonance technology is provided. The breathing monitor collects breathing data from a patient that indicates a breathing pattern of the patient. A model trained using machine learning using breathing patterns collected from patients known to have different stages of COVID-19 is used to process the collected breathing data and to determine whether the patient has COVID-19. The model further determines the stage of COVID-19. The breathing monitor can identify likely COVID-19 infections faster than existing tests and requires no contact between the patient and a medical professional, which is an improvement over existing COVID-19 detection technologies.

Abstract: A method for monitoring a patient includes receiving sensor signals from a sensor arrangement, extracting movement information from the sensor signals, determining a sensing period between the sensor arrangement and a body part of a patient based on the movement information, and determining a respiratory rate of the patient based on the sensor signals occurring during the period of contact. The sensor signals may be received from a sensor arrangement incorporated on or within a wearable item that moves relative to the body part of the patient. The sensor arrangement is in intermittent patterns of contact and non-contact with patient as a result of movement of the wearable item. The wearable item may be, for example, a pendant on a necklace.

Abstract: An active medical device, comprising a processor, a memory unit, and at least one of an accelerometer and a detection unit configured to detect a body impedance. During operation, the active medical device carries out the following steps a) measuring a body impedance of a patient with the detection unit during a first period of time to obtain time-dependent impedance data and calculating a power spectral density of the impedance data; b) alternatively or additionally, to step a), measuring an acceleration of a body of the patient with the accelerometer during the first period of time to obtain time-dependent acceleration data and calculating a power spectral density of the acceleration data; c) identifying coughing of the patient on the basis of the calculated power spectral density if at least 1% of all values of the power spectral density have a frequency of at least 1 Hz.

Abstract: The present disclosure provides a body shape data acquisition system that can acquire body shape data in a simplified manner. A body shape data acquisition system (50) includes an input unit (51) and a measurement unit (52) that acquire biometric information of a user, a storage unit (54) that stores a plurality of reference body shape data corresponding to the biometric information, a selection unit (53) that selects, from the reference body shape data stored in the storage unit (54), the reference body shape data corresponding to the user's biometric data acquired by the input unit (51) and the measurement unit (52), and an acquisition unit (55) that acquires the user's body shape data using the reference body shape data selected by the selection unit (53).

Abstract: A gait analysis system is disclosed. Some implementations of the gait analysis system include instrumented footwear including mobile sensors, a processor, a computer-readable data storage device storing program instructions. The program instructions can control the system to perform operations, including, determining gait information of a user performing a test routine, using the instrumented footwear. The operations can also include determining gait parameters based on the gait information. The operations can also include determining gait symmetry of the user based on the gait parameters. The operations can also include determining a gait signature of the user based on the gait parameters. The operations can also include determining a treatment effect based on the gait signature.

Abstract: Proposed are concepts for predicting the likelihood of a brain injury of a subject resulting from a fall event experienced by the subject. Such concepts may therefore be useful for determining a need for further medical assessment or treatment of a fall by the subject. According to an exemplary concept, data from one or more sensors is used to determine information about a fall of a subject. Such information is then used in conjunction with a prediction algorithm to derive a probability of a brain injury.

Abstract: Methods, systems and devices are provided for utilizing user movement data obtained from one or more wearable sensors during physical activity to compare individualized changes overtime, for example typical versus atypical movement patterns, with subgroup analyses for assessing changes between other users in order to develop an assessment of movement for, for example, tracking injury risk, performance, and/or rehabilitation. The movement information may comprise multi-sensor, high dimensional datasets. Techniques are provided for integrating human movement data from one or more wearable sensor with one or more additional data sources to define an individualized movement profile of a user's movements. The user or another individual may be notified when the user's movements deviate from this individualized movement profile.

Abstract: An external medical device includes monitoring circuitry configured to monitor a cardiac condition of a patient using the external medical device; and a controller configured to: receive at least one of patient input and non-patient user input of a patient's ability; determine a patient interaction mode of the external medical device based on the at least one of the patient input and the non-patient user input; and adapt the patient interaction mode of the external medical device over time based on the at least one of the patient input and the non-patient user input.

Abstract: An article of manufacture for providing a wearable face and hand proximity detector is disclosed. The article includes a bracelet to be worn on a user's wrist and a necklace to be worn around the user's neck. One of these devices includes a signal transmitter that may be received by a receiver element in the other device. The received signal being detected provides an indication that the user's hand is nearing the user's face. When the signal is detected, an alarm is generated. The alarm may be an auditory signal or a physical vibration that may be felt by the user.

Abstract: Systems and methods are disclosed to objectively identify sub-second behavioral modules in the three-dimensional (3D) video data that represents the motion of a subject. Defining behavioral modules based upon structure in the 3D video data itself—rather than using a priori definitions for what should constitute a measurable unit of action—identifies a previously-unexplored sub-second regularity that defines a timescale upon which behavior is organized, yields important information about the components and structure of behavior, offers insight into the nature of behavioral change in the subject, and enables objective discovery of subtle alterations in patterned action. The systems and methods of the invention can be applied to drug or gene therapy classification, drug or gene therapy screening, disease study including early detection of the onset of a disease, toxicology research, side-effect study, learning and memory process study, anxiety study, and analysis in consumer behavior.

Abstract: The present disclosure includes provides methods for assessing resting-state fMRI functional connectivity, resting-state MEGI functional connectivity, and/or task-based spatiotemporal auditory cortical activity latency in a subject to detect, monitor, and/or diagnose Tinnitus, with or without hearing impairment. The present disclosure also provides systems, devices, and methods for diagnosing Tinnitus and/or hearing impairment in a subject. Also provided are systems configured for performing the disclosed methods and computer readable medium storing instructions for performing steps of the disclosed methods.

Abstract: Transdermal optical sensing systems and methods of use are described. The systems include a main body, an internal reflection element arranged within the main body, with an internal reflection element surface exposed for contact with an epidermis, an optical source configured to project light into the internal reflection element, an optical detector arranged to detect reflected light that reflects internally within the internal reflection element from the internal reflection element surface, a controller configured to measure the light at the optical detector to determine the presence of one or more compounds within the epidermis, and a retention member attached to the main body, the retention member configured to wrap about a wrist of a patient.

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

Abstract: The present invention generally relates, in certain aspects, to relatively small devices applied to the skin, modular systems, and methods of use thereof. In some aspects, the device is constructed and arranged to have more than one module. For instance, the device may have a module for delivering to and/or withdrawing fluid from the skin and/or beneath the skin of a subject and a module for transmitting a signal indicative of the fluid delivered to and/or withdrawn from the skin and/or beneath the skin of the subject, a module for analyzing a fluid withdrawn from the skin and/or beneath the skin of the subject, or the like. In some embodiments, the modules are connectable and/or detachable from each other, and in some cases, the connections and/or detachments may be performed while the device is in contact with the subject, e.g., while affixed to the subject.

Abstract: Glucose prediction using machine learning (ML) and time series glucose measurements is described. Given the number of people that wear glucose monitoring devices and because some wearable glucose monitoring devices can produce measurements continuously, a platform providing such devices may have an enormous amount of data. This amount of data is practically, if not actually, impossible for humans to process and covers a robust number of state spaces unlikely to be covered without the enormous amount of data. In implementations, a glucose monitoring platform includes an ML model trained using historical time series glucose measurements of a user population. The ML model predicts upcoming glucose measurements for a particular user by receiving a time series of glucose measurements up to a time and determining the upcoming glucose measurements of the particular user for an interval subsequent to the time based on patterns learned from the historical time series glucose measurements.

Abstract: In one or more embodiments, a base unit of a wearable device for continuous analyte monitoring may include sensor memory circuitry and a sensor assembly. The sensor memory circuitry stores information (data) of at least one parameter of at least one component of the base unit, such as, e.g., the sensor assembly. The base unit is configured to couple to a transmitter unit of the wearable device and to transfer the information to the transmitter unit. Analyte determinations are made based at least in part on the information. Numerous other embodiments are provided.

Abstract: An interstitial fluid sampling device with mechanical, electrical, and/or chemical components to mitigate sample quality issues and/or measure the quality of collected samples to alert of and/or correct for quality issues. The device includes at least one sensor that is specific to an analyte in the interstitial fluid, at least one wicking component, and at least one component to ensure the quality of collected interstitial fluid.

Abstract: The invention applies to the analysis of the chemical composition of materials and can be used primarily in diagnostic medical equipment for noninvasive determination of hemoglobin and oxygen concentrations contained in the blood.

Abstract: Analyte sensors featuring an enzyme system comprising diaphorase and a NAD-dependent dehydrogenase may be utilized to detect inhibitors of diaphorase, provided that the transfer of electrons to a working electrode is rate-limiting with respect to the diaphorase. Such analyte sensors may comprise a sensor tail comprising at least a first working electrode, a first active area disposed upon a surface of the first working electrode, and an analyte-permeable membrane overcoating at least the first active area. The enzyme system comprises NAD, reduced NAD, or any combination thereof; a NAD-dependent dehydrogenase, such as NAD-dependent glucose dehydrogenase; and diaphorase. Inhibitors of diaphorase that may be detected include, for example, warfarin, dicoumarol, and similar compounds. A second active area may be present to facilitate detection of an analyte differing from the inhibitor of diaphorase.

Abstract: Example biosensor devices having wake-up batteries and associated methods are disclosed. One example device includes a biosensor that has a first electrode for insertion into a subcutaneous layer beneath a patient's skin, and a second electrode coupled to the first electrode for insertion into the subcutaneous layer, and a first battery to apply a voltage across the first and second electrodes, the first battery at least partially electrically decoupled from the electrodes. The device also includes a second battery having an anode material coupled to the first electrode for insertion into the subcutaneous layer, and a portion of the second electrode. The second battery is activatable upon immersion in an electrolytic fluid. The device also includes a wake-up circuit to receive a signal from the second battery and, in response, to electrically couple the first battery to the first and second electrodes to activate the biosensor.

Abstract: The present disclosure presents glucose monitoring systems and methods. One such system comprises a glucose monitoring sensor having at least a counter electrode, a reference electrode, and a working electrode; and a silicon-carbide-silicon-carbide-nanoparticles-electrospun-nanofibrous-membrane contacting the working electrode. The system further includes a glucose oxidase enzyme solution contacting the silicon-carbide-silicon-carbide-nanoparticles-electrospun-nanofibrous-membrane, wherein a conductive polymer membrane assists in binding the glucose oxidase enzyme composition with the silicon-carbide-silicon-carbide-nanoparticles-electrospun-nanofibrous-membrane. Other systems and methods are also provided.

Abstract: A biological property testing device includes a base comprising a primary surface extending in a base plane, and a first lancet station supported by the base. A first test strip channel provided in the base can have a main channel portion extending generally parallel with the base plane, and an angled channel portion that forms an angle with the main channel portion between 5 degrees and 90 degrees. The first test strip channel can house a biological test strip oriented so that a meter connecting end of the biological test strip is adjacent to the main channel portion and a sample end of the biological test strip is adjacent to the angled channel portion.

Abstract: A shieldable needle device (12) with a needle cannula (28), a hub (44) supporting the needle cannula, and a tip guard (24) axially movable along the needle cannula where, upon transition, the tip guard protectively surrounds the distal end (42) of the needle cannula. The needle device includes a pair of wings (60) extending laterally from opposing sides of the tip guard and connected to the hub. The pair of wings are transitionable between a first position and a second position, wherein transition of the pair of wings advances the tip guard from a proximal position to a shielding distal position. The wings include protrusions (66) which cause the longitudinal axis of the needle cannula to become offset from the opening (52) of the tip guard during advancement of the tip guard preventing the needle cannula from being reinserted through the tip guard after the tip guard has been transitioned to the distal position.

Abstract: Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.

Abstract: A system and method are provided for detecting and continuously monitoring Pupillary Light Reflex responses and neurological conditions to determine probability and degree of impairment to a user due to intoxication or neurological disorder. In one embodiment, the system includes a camera in a housing affixed to an article worn on the head of a user operable to enable the camera to view at least one eye of the user, a portable video capture device (VCD) wired or wirelessly coupled, or integrated to the camera to receive video therefrom, and software executed by a processor in the VCD. The software includes modules to locate and measure a change in a feature of the eye, extract data therefrom and predict a degree of impairment of the user, and output the probability and degree of impairment to the user and/or to a third party monitor. Other embodiments are also disclosed.

Abstract: Automated audio multi-issue comparison test (AMCT) protocols for deception detection. In one exemplary embodiment, testing equipment that may include an eye tracking device, such as an infrared camera, computer, keyboard, mouse, chin rest, and audio output device (headphones or speaker) is used. A series of Agree and Disagree statements regarding issues of interest are presented to the examinee in an audio format as by text-to-speech narration. Each statement must include an introductory phrase, topic phrase and declaration phrase. As statements are presented, a neutral image is presented on a visual display, then replaced by an image prompting the examinee to provide a response when the statement concludes. The eye tracker measures and records eye movements during the test. At the conclusion, ocular-motor measures and test question responses are combined by means of a logistic regression equation to compute the probability of deception.

Abstract: Provided is a method for predicting a PTSD diagnosis in a patient comprising receiving audio input data from a patient; determining one or more audio input indicators based on the audio input data, wherein each audio input indicator of the one or more audio input indicators represents a likelihood of a positive PTSD diagnosis based on the audio input data; receiving clinical assessment data from the patient; determining one or more clinical assessment indicators based on the clinical assessment data, wherein each clinical assessment indicator of the one or more clinical assessment indicators represents a likelihood of a positive PTSD diagnosis based on the clinical assessment data; combining the one or more audio input indicators and the one or more clinical assessment indicators using a prediction model chosen by a clinician; and determining a PTSD diagnosis in the patient based on the audio input data and the clinical assessment data.