Abstract: A medical imaging device configured to be inserted to a patient's body, comprising an elongated tube, comprising two or more cameras for capturing visual content in the vicinity of the device in different directions of view, a light source for illuminating a field of view of the two or more cameras, a wireless module configured to transmit data captured by the two or more cameras to a remote devices, and a power source for supplying power to the camera, the light source and the wireless module.

Abstract: Systems and methods for improving endoscopy procedures are described that provide not only a conventional real time image of the view obtained by an endoscope, but in addition, a near real time 3D model and/or a 2D flattened image of an interior surface of an organ, which model and image may be processed using AI software to highlight potential tissue abnormalities for closer examination and/or biopsy during the procedure. A navigation module interacts with other system outputs to further assist the endoscopist with navigational indicia, e.g., landmarks and/or directional arrows, that enhance the endoscopists' spatial orientation, and/or may provide navigational guidance to the endoscopist to assist manipulation of the endoscope.

Abstract: In one aspect, the present invention is an articulation joint for use in a low cost medical device such as an endoscope intended for a single use. In one embodiment, the articulation joint comprises a plurality of interconnected segments. In another embodiment, the articulation joint comprises an elongated tubular body. In another aspect, the present invention provides methods of manufacturing an articulation joint for use in a medical device.

Abstract: Disclosed is a flexible surgical instrument system, comprising a distal structural body comprising at least one distal structural segment each comprising a distal fixing disk and structural backbones; a proximal structural body comprising at least one proximal structural segment each comprising a proximal fixing disk, structural backbones and driving backbones; a plurality of cable pulling mechanisms operable to convert a rotational motion into a linear motion to turn the at least one proximal structural segment; and a driving unit to input the rotational motion to the plurality of cable pulling mechanisms; the driving unit comprises: a plurality of driving shafts operable to transfer the rotational motion to the plurality of cable pulling mechanisms, and a first end of each of the plurality of driving shafts is connected with each of the plurality of cable pulling mechanisms.

Abstract: The present invention discloses an ingestible endoscopy capsule including a permanent magnetic dipole, and an external positioning and orientation system to position and/or orientate the capsule in a target area including at least one magnet for positioning and/or orientating the endoscopy capsule within a patient, and one diagnostic imaging means.

Abstract: An endoscope unblocking flush system for back flushing a suction lumen of an endoscope includes a flush source providing pressurized water and a valve mechanism to cut off a suction source from the suction lumen and to open the suction lumen to flow of back flush water from the flush source. The valve mechanism includes a valve housing with ports to connect to the suction lumen, the suction source, and the flush source. A valve member within the housing has passages to connect the suction source to the suction lumen in a run state and to connect the flush source to the suction lumen in a flush state.

Abstract: A medical/dental handpiece comprises a housing having distal portion, the head portion having a bottom surface defining an opening. A motor and a light source are positioned with the handpiece, and the handpiece removably receives a light guide in alignment with the light source, to receive light from the light source. The light guide includes a probe which can be positioned adjacent or within a treatment area. The handpiece can be operated to activate only the light source, such that light is directed through the probe to or into the treatment area, to activate only the motor to rotationally or reciprocatingly drive the light guide, or to activate both the light source and the motor.

Abstract: A device to determine a state of the lacrimal layer of the eye includes at least one light source arranged to form a pattern of source points for projecting a plurality of light rays onto a cornea surface; a lens-camera system arranged to receive a respective plurality of reflected light rays reflected on the cornea surface, thereby forming a pattern of image points; and a computational unit arranged to determine on the basis of the image points the state of the lacrimal layer of the eye and/or to determine on the basis of the image points data representative for the state of the lacrimal layer of the eye and to provide the data representative for the state of the lacrimal layer of the eye to a user.

Abstract: A Bowman's Refractive Index (BRI) for quantification of microdistortions in Bowman's Layer (BL) after Small Incision Lenticule Extraction (SMILE) is defined for a patient. BRI is summation of one or more areas of the OCT image of anterior edge of Bowman's layer, quantifies the smoothness of the Bowman's layer. The anterior edge of Bowman's layer is segmented into pixels. After segmentation, a 3rd order polynomial is curve fit to the segmented pixels of the edge of Bowman's layer. BRI is calculated by segmentation of the 3-Dimensional (3-D) OCT image. BRI acts as a marker for mechanical stability and is useful for diagnosis of disease and prognosis of treatments in human.

Abstract: An ophthalmic apparatus to examine an examinee's eye includes: a first optometry unit to perform a first examination of the examinee's eye; a second optometry unit to perform a second examination of the examinee's eye; a drive unit to cause relative movement of the first and second optometry units in three-dimensional manner relative to the examinee's eye; a controller to control the drive unit; a selection receiving unit to receive a selection signal representing at least one selected from the first second examinations; and a face photographing unit to photograph a face image including at least one of examinee's right and left eyes. The controller switches, according to the selection signal, between a first path for alignment of the first optometry unit with the eye detected from the face image and a second path for alignment of the second optometry unit with the eye detected from the face image.

Abstract: Devices, systems and methods are disclosed which relate to remotely monitoring the health of an individual. The individual wears a health monitoring device, with an attached strap, capable of sensing characteristics of the individual. These characteristics may include voice level and tone, movements, blood pressure, temperature, etc. The device allows individuals to constantly monitor their health without having to physically visit a doctor or other health care professional. Wireless communication, for instance with an Internet Protocol Television (IPTV) set-top box, allows measurements to be made and evaluated by a computerized healthcare service provider. For a more accurate evaluation, measurements are sent over the INTERNET to a service. The device communicates with services in order to diagnose the individual based upon the characteristics.

Abstract: The system and method disclosed collects user reported, self-monitored On-task/Off-task Behavior, Fidgeting Behaviors and Walking/Running behaviors as quantified by motion sensors and an intelligent scheduling system. The collected data tells the reminder device what environment a user is scheduled to be in at any point in time in order to appropriately collect behavioral information and use said information to encourage users to be mindful of their own actions and behaviors in order to increase time spent on-task.

Abstract: Systems and methods are provided for performing OCT vibrography based on the synchronization of components of the OCT vibrography system. An A-scan trigger is employed to synchronize the operation of the scanning subsystem that scans the sample beam and an acoustic stimulus source that generates an acoustic stimulus for vibrographic measurements. The acoustic stimulus source is controlled such that when the scanning subsystem dwells on an imaging line selected for vibrography measurements, the acoustic stimulus is generated over a plurality of A-scans and the phase of the acoustic stimulus is locked to the A-scan trigger, such that the phase of the acoustic stimulus is incrementally modified with each A-scan. The accumulation of the acoustic phase is therefore synchronized to the A-scan trigger. The synchronization, providing synchronized acoustic phase evolution during each acoustic phase waveform cycle, permits the use of the OCT vibrography system for simultaneous anatomical and functional imaging.

Abstract: An optoacoustic probe including an ultrasound transducer array, an acoustic lens and a light path separated from the transducer array by an isolator to mitigate light energy from the light path from reaching the transducer array. The isolator being formed from a mixture including a flexible carrier, a coloring and between 10% and 80% by volume micro-bubbles. The isolator mixture being adapted to both absorb light energy and the optoacoustic response to light energy. In an embodiment, an optoacoustic probe also comprises an optical window and/or a diffuser, and the isolator also separating the transducer array from these components.

Abstract: A body monitoring sensor system is described and wherein a sensor module is attachable to a thermally insulated article of warmth, such as an article of apparel, having a thermal insulation of a known clo index value and wherein the sensor system has various sensors to produce various atmospheric and body condition signals to feed a computer having a processor. The processor is programmed to perform calculations to generate a output signals indicative of the corrective action required based on the protection offered by the clo index of the thermal insulation of the article of warmth and taking into account the calculated wind chill temperature and humidity as well as the wearer person's body temperature and humidity conditions to provide warmth and comfort to the user person under the actual atmospheric conditions.

Abstract: A fluid control device (10) includes a container (13), a pump (11), a solenoid valve (12), and a capacitor. The pump (11) is driven by a main power source, and is capable of pressurizing or depressurizing the inside of the container (13). A suction port and a discharge port of the pump (11) internally communicate with each other. The solenoid valve (12) is connected at both ends thereof to the container (13) and the pump (11). If the voltage of the main power source is reduced or lost, the solenoid valve (12) releases pressure in the container (13) by being driven by the power stored in the capacitor or secondary battery.

Abstract: A measurement apparatus for measuring biological information includes a sensor that executes selectively at least a first detection mode or a second detection mode, and a controller. The controller controls switching to the second detection mode based on output of the sensor while the sensor is in the first detection mode.

Abstract: Disclosed is an electronic device. The electronic device according to an embodiment includes a memory and a processor electrically connected with the memory, wherein the processor is configured to obtain an identification of a portion of the media data and a sequence of heart rate (HR) data of a user of the electronic device while the portion of media data is output, and store, in the memory, the identification of the portion of the media data when the HR data sequence satisfies a specified condition.

Abstract: An electronic device includes a light emitter emitting visible light, an infrared emitter emitting infrared light, at least one detector detecting an electromagnetic wave, and at least one processor configured to obtain a user input to obtain spectral data of a target object, in response to obtaining the user input, emit the visible light by using the light emitter and emit the infrared light by using the infrared emitter, obtain a first reflected signal of the visible light reflected by the target object and a second reflected signal of the infrared light reflected by the target object, using the at least one detector, and generate the spectral data of the target object based on the first reflected signal and the second reflected signal.

Abstract: Respiratory variables are estimated on a per-breath basis from airway pressure and flow data acquired by airway pressure and flow sensors (20, 22). A breath detector (28) detects a breath interval. A per-breath respiratory variables estimator (30) fits the airway pressure and flow data over the detected breath interval to an equation of motion of the lungs relating airway pressure, airway flow, and a single-breath parameterized respiratory muscle pressure profile (40, 42) to generate optimized parameter values for the single-breath parameterized respiratory muscle pressure profile. Respiratory muscle pressure is estimated as a function of time over the detected breath interval as the single-breath parameterized respiratory muscle pressure profile with the optimized parameter values, and may for example be displayed as a trend line on a display device (26, 36) or integrated (32) to generate Work of Breathing (WoB) for use in adjusting settings of a ventilator (10).

Abstract: Method and system for monitoring an internal electrical impedance of a biological object including Internal Thoracic Impedance (ITI) comprising placing two arrays of electrodes on opposite sides of the biological object, wherein each of said two arrays comprise three equally spaced electrodes; imposing an alternating electrical current between pairs of the electrodes and obtaining voltage signals representative of a voltage drop thereon, calculating two values of internal electrical impedance of the biological object corresponding to the uttermost electrodes of said two arrays of electrodes placed on the opposite sides of the biological object.

Abstract: Apparatus for transcutaneous electrical nerve stimulation in a user, the apparatus comprising: stimulation means for electrically stimulating at least one nerve; an electrode array connectable to said stimulation means, said electrode array comprising a plurality of electrodes for electrical stimulation of the at least one nerve, said electrodes having a pre-formed geometry and known electrode-skin contact area size when in complete contact with the user's skin; monitoring means electrically connected to said stimulation means for monitoring the impedance of the electrical stimulation through said electrode array; and analysis means for analyzing said impedance to estimate a change in the electrode-skin contact area.

Abstract: In one aspect, a method comprises: receiving data indicative of at least one phase image captured using a magnetic resonance imaging (MRI) device during delivery of thermal therapy by a thermal therapy applicator to a target volume within a patient's body; and processing said at least one phase image; wherein said processing said at least one phase image comprises: applying a first mask; applying phase unwrap; and applying a second mask.

Abstract: Markers and related systems and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The marker includes one or more photosensitive diodes for transforming light pulses striking the marker into electrical energy, one or more antennas, and a switch coupled to the photodiodes and antennas such that the light pulses cause the switch to open and close and modulate radar signals reflected by the marker back to a source of the signals. The antenna(s) may include one or more wire elements extending from a housing, one or more antenna elements printed on a substrate, or one or more chip antennas. Optionally, the marker may include a processor coupled to the photodiodes for identifying signals in the light pulses or one or more coatings or filters to allow selective activation of the marker.

Abstract: An exemplary tissue detection and location identification apparatus can include, for example, a first electrically conductive layer at least partially (e.g., circumferentially) surrounding a lumen, an insulating layer at least partially (e.g., circumferentially) surrounding the first electrically conductive layer, and a second electrically conductive layer circumferentially surrounding the insulating layer, where the insulating layer can electrically isolate the first electrically conductive layer from the second electrically conductive layer. A further insulating layer can be included which can at least partially surrounding the second electrically conductive layer.

Abstract: In respiratory monitoring, a breathing cycle detector (44) detects a breath interval in airway pressure and/or flow data. A respiratory parameters estimator and validator (30) asynchronously fits the airway pressure and airway flow data to an equation of motion of the lungs relating airway pressure and airway flow to generate asynchronously estimated respiratory parameters for the breath interval, using a sliding time window that is not synchronized with the breath interval. The asynchronously estimated respiratory parameters for the breath interval are validated using at least one physiological plausibility criterion defined with respect to the breath interval. Responsive to failure of the validation, the airway pressure and airway flow data are synchronously fitted to the equation of motion of the lungs to generate synchronously estimated respiratory parameters for the breath interval. The synchronous fitting is performed in a time window aligned with the breath interval.

Abstract: Aspects of the present disclosure provide methods, apparatuses, and systems for dynamic starting rates for guided breathing. According to an aspect, a user's initial breathing metric is determined. A multiplier is then determined, where the multiplier varies as a function of the initial breathing metric within a range. The level of intensity of the multiplier may vary, and may be a dynamic feature based on the determination of the user's initial breathing metric. Once the multiplier is determined, the multiplier is applied to the user's initial breathing metric to determine a starting breathing metric for guided breathing. The starting breathing metric is slower than or equal to the user's initial breathing metric.

Abstract: A breath parameter measuring device is described which takes into account breathing patterns which historically have been incompatible with accurate measurements. In particular, during fast breathing patterns, the sensor performing the measurement may not be able to respond quickly enough to provide the true reading. The disclosure may be useful for example in the case of neonatal breath carbon dioxide measurements.

Abstract: Apparatus for quantifying the amount of re-breathing due to bedding materials. The re-breathing analyzer applies heated air to the material under test through an exhaust port in a probe and receives return air from an intake port in the probe. The exhaust and intake ports are placed to engage the material under test when the probe is in contact with the material. In one embodiment, the probe has a surface that is exposed through a top surface of a housing for the analyzer whereby the material under test is placed on the top surface for testing. The analyzer includes a differential temperature measuring instrument that determines the temperature of the return air, where an increase of the temperature of the return air above the temperature of the ambient air indicates the presence and quantity of re-breathing due to the material under test.

Abstract: A wearable monitoring system and associated method that is configured to (i) determine three dimensional displacement of the spine of a subject's chest wall with respect to the subject's spine, (ii) process the three dimensional anatomical data, (iii) determine at least one respiratory parameter associated with the monitored subject and value thereof as a function of the three dimensional anatomical data, and (iv) determine a respiratory disorder as a function of the determined respiratory parameter and value thereof.

Abstract: A wearable respiration monitoring system having a transmitter coil that is adapted to generate and transmit multi-frequency AC magnetic fields, a plurality of receiving coils adapted to detect variable strengths in the AC magnetic fields and generate AC magnetic field strength signals representing anatomical displacements of a monitored subject, and at least one accelerometer that is configured to detect and monitor anatomical positions and movement of the subject, and generate and transmit accelerometer signals representing same. The wearable monitoring system further includes an electronics module that is adapted to receive the AC magnetic field strength signals and accelerometer signals, and determine at least one respiratory disorder as a function of the AC magnetic field strength signals and at least one anatomical position of the subject as a function of the accelerometer signals.

Abstract: A posture improvement device, system, and method. The system for improving posture may comprise: a sensor device; posture improvement software program, comprising a posture improvement system interface; and one or more user devices. The sensor device may be physically associated with a user and may communicate with the posture improvement software program. The sensor device may comprise: one or more sensors for monitoring positions and movements of the user. The system may calculate one or more optimum postural positions for the user, based on data communicated by the sensor device and collected information about the user. The system may monitor a conformance of the user with the optimum postural positions and may display the conformance on the posture improvement system interface. The system may detect and notify the user of one or more non-conformances, such that a user is reminded to maintain at least one optimum postural position.

Abstract: The present disclosure relates generally to a method for providing motion biofeedback to a user while the user performs an activity, where the biofeedback can occur in real time or after discrete points in time (e.g., after a drive phase or maximum velocity phase). The method includes determining an activity type performed by the user; determining a target value for one or more motion characteristics associated with the activity, wherein the target value is determined by historical collected motion data; receiving motion data related to the activity as the user performs the activity; comparing the motion data to the target value; and transmitting feedback to a feedback device based on the comparison to the target value, wherein the feedback corresponds to a motion adjustment proportional to a deviation of the motion data relative to the target value.

Abstract: The present invention relates to a method for estimating the relative orientation between a tibia (11a) and a femur (11b) of a lower limb (10) of a person (1), the method being characterised in that it comprises the steps of: (a) During at least one reference movement of said lower limb (10) from a reference position, acquiring by first inertial measuring means (20a) integral with the tibia (11a) and by second inertial measuring means (20b) integral with the femur (11b) reference accelerations and angular velocities; (b) Estimating a plurality of morphological parameters of said lower limb (10), as a function of said measured reference accelerations and angular velocities; (c) Determining a relative orientation in said initial position between said tibia (11a) and femur (11b), as a function of said estimated morphological parameters of said lower limb (10); (d) During a working movement of said lower limb (10) from an initial position, acquiring by the first inertial measuring means (20a) and the second in

Abstract: A device is used to monitor, in real-time, one or more environment conditions of an environment in which a user is located. Based on the monitoring, an alert condition relating to the environment is detected. Based on detecting the alert condition, on-demand testing of a sensory component of the user is initiated. The on-demand testing tests for a selected condition relating to the health of the user.

Abstract: Embodiments herein include gas sampling catheters, systems and related methods. In an embodiment, a gas sampling catheter is included. The catheter can include a catheter shaft having a proximal end and a distal end, the catheter shaft defining a lumen therein. The catheter can include a gas sampling port providing fluid communication between the exterior of the catheter shaft adjacent the distal end of the lumen of the catheter shaft. The catheter can further include a sensor element disposed in fluid communication with the lumen, the sensor element configured to detect a component of a gaseous sample. The sensor element can include a first measurement zone comprising a plurality of discrete binding detectors. Other embodiments are also included herein.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

Abstract: Systems, methods, and other techniques for estimating the level of an analyte present in a patient during a time interval using electrocardiogram (ECG) signals. The estimate can be improved using information about the patient's posture.

Abstract: The present disclosure is directed to a method and device to determine the hemoglobin value of a mammal. The device includes a plurality of light emitting diodes, one or more sensors and a processor.

Abstract: An oxygen measurement device includes a catheter including a flexible hollow shaft, the flexible shaft having an open port configured to allow urine from a bladder to flow into the open port, and a urinary passage in communication with the open port configured to discharge the urine; and an oxygen sensor including an oxygen sensor main body capable of detecting oxygen in the urine, the oxygen sensor being disposed in the catheter and configured such that the oxygen sensor main body is in contact with the urine flowing in the urinary passage.

Abstract: An eye-mountable device includes layer(s) of polymer material defining a body. The body includes a first side and a second side extending from a first end to a second end. The first side opposes the second side and curves inwardly toward the second side. The second side curves outwardly away from the first side. The body includes an anterior surface and a posterior surface extending from the first side to the second side and from the first end to the second end. The anterior side opposes the posterior side. The posterior surface has a concave shape. The device includes a substrate in the body including a mounting platform disposed proximally to a middle of the second side. The device includes, on the mounting platform, electronics that interact with a biological environment and monitor health-related information. The body may have a thickness profile that prevents the device from undesired movement.

Abstract: Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.

Abstract: A system and method for preparing a diagnostic fluid sample for use with a fluid assay system. The method comprises the steps of: amplifying the fluid sample to increase the number of cells subject to being tested; drawing a first volume of the fluid sample into a first syringe of a dual-barrel syringe and dispensing the first volume of the fluid sample through a media filter. The method further comprises the steps of placing the bacteria-laced filter into a lysis module; dispensing a first portion of a lysis buffer into the lysis module from the second syringe of the dual-barrel syringe; and dispensing a second portion of the lysis buffer through the media filter into a disposable cartridge of a fluid assay system.

Abstract: An apparatus for performing phlebotomy through a peripheral intravenous line. The apparatus includes an introducer and a catheter configured to advance the catheter through a peripheral intravenous line. A y-adapter with a port of larger diameter is configured to receive the catheter and place in fluid communication with the peripheral intravenous line. When advanced the catheter is configured to transport a bodily fluid (i.e. blood) to a volume outside of the body.

Abstract: Physiological variables, metrics, biomarkers, and other data points can be used, in connection with a non-invasive wearable device, to screen for, and predict, mental health issues and cognitive states. In addition to metrics such as heart rate, sleep data, activity level, gamification data, and the like, information such as text message and email data, as well as vocal data obtained through a phone and/or a microphone, may be analyzed, provided user authorization. Applying predictive modeling, one or more of the monitored metrics can be correlated with mental states and disorders. Identified patterns can be used to update the predictive models, such as via machine learning-trained models, as well as to update individual event predictions. Information about the mental state predictions, and updates thereto, can be surfaced to the user accordingly.

Abstract: A monitoring device comprising at least one measurement module for measuring at least one physiological parameter of the crew member, at least one consolidation module for consolidating the measured physiological parameter or parameters, a fusion module for fusing the consolidated physiological parameter or parameters in order to detect at least one physiological status of the crew member, a filtering module for filtering the physiological status or statuses, a determination module for determining a level of incapacity of the crew member, a transmission module for transmitting a signal indicative of the level of incapacity of the crew member to a user device.

Abstract: A vehicular notification apparatus detects an emotion of a driver based on a line-of-sight detection result and a brain activity detection result, and performs control to suppress notification in response to that the detected emotion of the driver is uncomfortable.

Abstract: System and apparatus for measuring biopotential and implementation thereof. A device for mitigating electromagnetic interference (EMI) thereby increasing signal-to-noise ratio is disclosed. Specifically, the present disclosure relates to an elegant, novel circuit for measuring a plurality of biopotentials in useful in a variety of medical applications. This allows for robust, portable, low-power, higher S/N devices which have historically required a much bigger footprint.

Abstract: A medical device includes a sensor interface for measuring one or more physiological signals of the patient; at least one motion detector for detecting movement of the device; a processor coupled to the sensor interface and the at least one motion detector; and a memory communicatively coupled to the processor and comprising instructions that cause the processor to receive movement information comprising at least acceleration information and heading information from the at least one motion detector; detect movement of the medical device from the movement information, wherein the movement of the medical device comprises a distance traveled by the medical device and a direction traveled by the medical device; and estimate a current location of the medical device relative to a previous location of the medical device using dead reckoning based at least in part on the distance and direction traveled by the medical device.

Abstract: A system includes an implantable body configured for implantation in a subgaleal extracranial position, the implantable body including a first electrode array including a first elongated body comprising first and second electrode contacts separated from one another by a distance selected to facilitate the detection of brain electrical activity and a unit coupled to the first electrode array. The unit includes a processor analyzing the detected brain electrical activity to determine whether an epileptic event has occurred and generating epileptic event data based on this determination and a transceiver controlled by the processor to wirelessly transmit epileptic event data to and from a remote computing device.