Abstract: There are disposed, in a width direction of an anvil roll, a plurality of first projections for producing joint portions where a pair of sheets are jointed to each other; each of the first projections extends in a circumferential direction of the anvil roll and includes a carrying groove carrying an elastic member while the elastic member has entered in the groove; and between one first projection and another first projection adjacent to each other in the width direction, at least one receiving part for receiving the pair of sheets is arranged.

Abstract: A tampon insertion device for inserting a tampon from a tampon applicator into a vaginal canal. The devices includes a hollow casing having an open distal end, a proximal end, a top wall extending between the proximal and distal ends, an open bottom opposing the top wall, and a clamp portion located at the distal end of the casing. The device further includes a plunger actuator located in the interior of the casing for linear movement therein, and a handle slidably positioned external to the casing and connected to the actuator such that linear sliding movement of the handle with respect to the casing causes a corresponding linear movement of the actuator within the casing. A method of inserting a tampon is also provided.

Abstract: The present invention discloses a method of manufacturing a diaper that has multiple moisture sensing elements on interior side of its bottom impermeable layer or on any surface of the top permeable layer. The moisture sending elements are made by spraying conductive ink on a moving sheet of either the bottom impermeable layer or the top permeable layer, before other layers of the diaper are attached. Spraying of conductive ink on the moving sheet causes parallel lines of conductive inks to be formed on the layer. The parallel lines of conductive ink run through the entire length of either of the layers and are designed to get connected with a detecting device. When a user urinates inside the diaper, the moisture causes a closed circuit between at least two of the parallel lines of conductive inks. These formations of closed circuits, between parallel lines of conductive inks, are detected by the detecting device.

Abstract: An absorbent article comprising an absorbent core having at least two longitudinally extending channel-forming areas and a wetness indicator. The core wrap comprises a top side and a bottom side, which are attached to each other through areas substantially free of absorbent material, so that when the absorbent material swells upon absorption of a liquid the core wrap forms channels along these areas substantially free of absorbent material.

Abstract: A material engagement element sheet formed from a sheet material (10) incorporates a pattern of material engagement element slots (14), each slot containing an array of material engagement elements (20) which have a tapered distal section (30), a flange section (34) and a proximal section (32) which is attached to an edge of the slots in the sheet material. The material engagement element sheet material may be a single layer of shape memory material, or the sheet material may be a composite of different layers some of which may include pre-strained shape memory materials with distinguishable activation parameters. The material engagement element slot configuration allows for the simultaneous processing of the material engagement elements. The material engagement elements may be processed such that they are in a state that is substantially perpendicular to the surface of the material engagement element sheet.

Abstract: Provided herein is a balanced locking pawl. In particular, the center of gravity of the locking pawl is located at or near the pivot point of the locking pawl. The balanced approach allows for a faster locking response during the rebound (whiplash/return) forces of a crash.

Abstract: Provided is a wheelchair that can be easily operated with either a right or left hand. The wheelchair according to the present invention is provided with: a right-left pair of first handrims connected to handrim spokes; a right-left pair of second handrims connected to spokes; a first rotary shaft for transmitting a first rotational force generated by rotation of the left first handrim to a right wheel; and a second rotary shaft for transmitting a second rotational force generated by rotation of the right first handrim to a left wheel, wherein a first power transmission device on a right inner shaft of a right drive mechanism meshes with a second power transmission device on the second rotary shaft, and a third power transmission device on a right outer shaft of the right drive mechanism meshes with a fourth power transmission device on the first rotary shaft.

Abstract: The electric vehicle according to the present invention includes a moving base capable of traveling by electromotive drive, a seat including a seating part having a seating surface and disposed on the moving base, and a back plate used as a seat back corresponding to the seating surface and disposed on the moving base, the seat can move between a seating position with the seating surface facing upward, and a retracting position with the seating part retracted forward from the seating position, the back plate can be moved between a standing-up position located rearward and upward with respect to the seating part of the seat when at the seating position, and a lying-down position located forward of the standing-up position, and the back plate includes a baggage carrier formed on a back surface facing upward when at the lying-down position and allowing baggage to be placed thereon.

Abstract: A hybrid seating cushion made up of a cushion base and a cushion insert. The cushion base has a seating surface in which a void in or extending through the cushion base is formed. A cushion insert such as an air bladder or fluid sack is positioned within the void. A lip or upper surface around an opening in the void overhangs at least a portion of the cushion insert, thereby minimizing the size and corresponding negative effects of a transition area where the base and the insert overlap.

Abstract: A powered wheelchair comprises a frame and an arm assembly that includes an arm that is pivotably coupled to the frame. The arm assembly includes a wheel coupled to the arm. A drive system is coupled to the arm assembly and configured to drive a drive wheel. An arm limiter is pivotably coupled to the suspension and coupled to one or more of the arm assembly and the drive system in an engaged position. The arm limiter is configured to limit movement of the arm assembly in the engaged position.

Abstract: A multi-cell inflatable jack includes a plurality of jack elements. Each of the plurality of jack elements includes a body having a predetermined perimeter shape and defining a perimeter chamber and a central chamber. A valve is coupled to the body and configured to provide air flow to one of the perimeter chamber or the central chamber. A plurality of flow control stringers are located between the first chamber portion and the second chamber portion and are configured to control an air flow rate into each of the perimeter chamber and the central chamber. At least one fastener is formed on the body and configured to attach the jack element to at least one additional jack element in a multi-cell stack.

Abstract: An inflatable cushion comprising; a cover; a base; a communication device; a microcontroller; a power source; a gas pump; a primary tube; a blow off valve; two-way valves; a plurality of secondary tubes; and a plurality of bladder pods with pressure sensors.

Abstract: A person lifting apparatus includes a strap movement system. The person lifting device includes a housing and a lifting strap feeding device located in the housing. The lifting strap feeding device includes a motor connected to a drum and a lifting strap wound on the drum. A sensor provides a signal indicative of force on the lifting strap. A controller receives the signal from the sensor. The controller controls operation of the motor based on the signal. A user input is used to place the strap movement system in a fast mode during which the controller speeds up operation of the motor from a normal operating speed.

Abstract: An apparatus comprises a tubular structure. The tubular structure generally comprises a U-shaped portion, a first lever arm, and a second lever arm. The first lever arm generally comprises a first curved portion, a first straight portion, and a first bent portion. The second lever arm generally comprises a second curved portion, a second straight portion and a second bent portion. The U-shaped portion is generally aligned within a first plane. The first lever arm is generally aligned within a second plane. The second lever arm is generally aligned within a third plane. The second and the third planes are generally parallel to each other and perpendicular to the first plane.

Abstract: A method and a portable prone surgical positioning device are provided which includes: a base frame assembly having a length varying assembly; a pair of chest supporting frames for a patient to lay in prone position thereupon; a width varying assembly connected to the pair of chest supporting frames; and a curvature varying assembly, connected to the base frame assembly and the width varying assembly, operable to change a curvature of the pair of chest supporting frames.

Abstract: A frame module includes a frame configured to enclose a portion of a user, and at least one reinforcement belt of which both end portions are connected to both sides of the frame, thereby restricting a splaying level of the frame in a predetermined direction.

Abstract: An apparatus for the treatment of arthrofibrosis, has a base having first and second opposing ends and a hole or recess adjacent the first end for enabling connection of the base to a chair to restrict movement of the base relative to the chair. A block is removably attached to the base and is movable between the first and second ends for abutting the toes of a foot of a user of the apparatus placed between the block and the hole or recess. The block is slidable along a guide on the base for enabling adjustment of the block between the first and second ends of the base. A clamp clamps the block in position on the base.

Abstract: A method for exercising a joint and a limb including the following: preventing movement of an exercise device actuation member in a first direction unless pressure exerted by the limb against the actuation member is equal to or greater than a predetermined first target pressure; permitting movement of the actuation member in the first direction at a first predetermined speed when pressure exerted by the limb against the actuation member is equal to or greater than the predetermined first target pressure; preventing movement of the actuation member in a second direction unless pressure exerted by the limb against the actuation member is equal to or greater than a predetermined second target pressure; and permitting movement of the actuation member in the second direction at a second predetermined speed when pressure exerted by the limb against the actuation member is equal to or greater than the predetermined second target pressure.

Abstract: An exoskeleton system is passively powered and pneumatically operated. The system may be a lower-limb system for walking gait restoration. The system may include a first linear actuator located in front of an upper leg section and a second linear actuator located behind a lower leg section.

Abstract: A pair of detachable crutches extends in a longitudinal direction, where each of the detachable crutches includes a metal ball having magnetic properties and a holder having magnetic properties. A magnetic force is generated between the metal ball provided at one of the crutches and the holder provided at the other one of the crutches so as to maintain attachment therebetween. Each of the crutches further includes a sensor configured to sense whether the metal ball and the holder have been attached to each other.

Abstract: A vaporizing and vapor heating assembly includes at least one vaporizing element fluidically coupled to at least one reservoir and configured to discharge vapor and a heater assembly operably coupled to the at least one vaporizing element. The heater assembly including at least one heating element configured to heat the discharged vapor.

Abstract: A storage device having a cylindrical housing with a first end, a second end and cylindrical side, wherein the ends are closed and the cylindrical side has one or more apertures. There is a cylindrical cover for each of the one or more apertures that slidably fit over the cylindrical side of the cylindrical housing and able to slide about the cylindrical side exposing or covering the one or more apertures.

Abstract: A tray for processing platelet rich fibrin includes a base having at least one alignment structure, a screen attachment having at least one alignment structure for engagement with the base, and a lid having at least one alignment structure for engagement with the base and the screen attachment. The screen attachment includes a screen offset between the top and bottom surface of the screen. When the screen attachment is placed on the base with the top surface facing upward, the lid is configured to compress a fibrin clot placed on the screen to a first thickness, and when the screen attachment is placed on the base with the bottom surface facing upward the lid is configured to compress a fibrin clot placed on the screen to a second thickness different from the first thickness.

Abstract: A personal thermoelectric-cooling and heating case includes a first rigid chamber and a temperature regulated second rigid chamber. The first rigid chamber accommodates electronic circuitry. The first rigid chamber also extends lengthwise along a longitudinal axis and includes a first end portion, a second end portion, and a thermoelectric-cooling device. The temperature regulated second rigid chamber includes a bay structure configured to accommodate an item that is subject to temperature regulation. The temperature regulated second rigid chamber (i) extends lengthwise along a longitudinal axis and includes a first end portion and a second end portion, (ii) is coupleable to the first rigid chamber in a lengthwise direction, and (iii) includes a direct heating element thermally coupled to the bay structure. The first rigid chamber and the temperature regulated second rigid chamber together form a housing.

Abstract: An aseptic connector assembly includes a body portion having a receptacle configured to receive a corresponding fill connector. A pivot portion is movably coupled to the body portion, the pivot portion having a channel formed therein. A conduit portion is slidably disposed within the channel formed in the pivot portion. The pivot portion has a ready position and an operative position, the pivot portion being adjustable from the ready position to the operative position via relative movement with respect to the body portion.

Abstract: The present invention is a method of making excipient free N-Acetylglucosamine tablets and also the excipient free N-Acetylglucosamine tablets in a variety of sizes, in particular 10 gram tablets. These excipient free tablets are palatable and suitable for consumption by horses, smaller animals and humans. In the method of making these tablets, of N-Acetylglucosamine powder is mixed with a specific amount of water, to bring about a moldable mass which is formed into suitably sized tablets through compression in a tablet mold. The solvent water is then allowed to evaporate leaving behind an excipient free N-Acetylglucosamine tablet.

Abstract: A modular dispensing apparatus for dispensing articles includes a hub containing electronics and have a plurality of side walls, with each side wall having a first coupling member that faces outward. The apparatus further includes a plurality of cartridges for holding the articles to be dispensed. Each cartridge has an inner wall that includes a second coupling member that is configured to mate with the first coupling member for detachably attaching the cartridge to a respective side wall of the hub. The cartridges are disposed radially beyond the hub such that the plurality of cartridges surround the hub. Each cartridge has an openable lid to provide access to an interior compartment of the cartridge for holding the articles.

Abstract: A non-sticky body surface patch is provided, which is attachable on a body surface to add a look of fullness to the body surface, exhibits excellent followability to skin deformation, and imposes little burden on body surfaces and thus is widely applicable to body surfaces. The non-sticky body surface patch includes a silicone rubber having a thickness in the range from 50 to 600 ?m, wherein the silicone rubber consists of a silicone rubber composition having a rubber hardness of 20 or less measured with a Type A durometer as defined in JIS K6249 standard.

Abstract: The subject matter of the present invention is a cosmetic or pharmaceutical composition for controlled moisturizing and release of active molecule(s), comprising at least one emulsifier having an enzyme cleavable bound, at least one emollient, at least one polar solvent, and water, forming together a macroscopically homogenous liquid crystals emulsion. In some embodiments of the invention, the composition also includes at least one ingredient having a cosmetic or pharmaceutical activity.

Abstract: Cleansing compositions can include hinokitiol; and a 2-pyridinol N-oxide material; wherein the ratio by weight of the 2-pyridinol N-oxide material to the hinokitiol is about 1:4 to about 2:1 and the combination of the 2-pyridinol N-oxide material and hinokitiol includes about 9 ppm or more by weight of the cleansing composition.

Abstract: The disclosure relates to compositions for treating keratinous substrates, such as the hair, comprising monoethanolamine and at least one carboxylic acid, as well as systems and methods for treating keratinous substrates with the compositions.

Abstract: Methods and kits for treating hair or preventing damage in the relaxing of hair are disclosed herein. Hair that is damaged during a relaxing treatment with hydroxide-containing relaxing agents, can be treated with formulations containing one or more active agents. The active agent formulations can be applied simultaneously with the hair relaxing formulation, or optionally applied immediately following application of the relaxing formulation, to reduce damage and breakage. Use of the active agent formulation along with a relaxing treatment can be used to control the level of curl achieved or retained in the relaxed hair, as compared to the natural amount of curl in the untreated hair.

Abstract: A detergent composition and a method of washing/cleaning urushiol at least partially, more typically substantially or completely off a surface of human skin or clothing. The detergent composition is typically a non-buffered composition that contains one or more C12 surfactants, typically at least a sodium lauroyl sarcosinate and the detergent composition is typically free of one or more of (1) any nonylphenol ethoxylate; (2) any pharmaceutically active drug or prodrug; (3) any salt in an amount that affects the functional characteristics of either of the solely C12 surfactants; (4) any salt in granular form; and/or (5) any ethoxylate that is a stand-alone ingredient.

Abstract: A mouth rinse composition with a cationic antimicrobial agent and an anti-stain agent, which is a functionalized polyethylene glycol. A dentifrice composition with a cationic antimicrobial agent and an anti-stain agent, which is a functionalized polyethylene glycol. The cationic antimicrobial agent is a quaternary ammonium salt, such as cetyl pyridinium chloride, or a metal ion source, such as stannous fluoride.

Abstract: The invention relates to a composition, in particular a cosmetic composition, characterized in that it comprises:—at least one monoglyceride,—at least one tartaric ester of monoglycerides based on C12-C22,—at least one UV filter,—at least one HLB surfactant greater than 10, and—at least one hydrophilic gelling agent wherein the content of said one or more surfactant(s) having a HLB greater than 10 is comprised between 0.2% and 10% by weight, based on the total weight of the composition.

Abstract: A hair dye that is safe for human bodies and has a high hair dyeing effect is provided. The hair dye consisting of: a reaction solution (A) comprising: a substance having a specific flavonoid skeleton represented by the following general formula (1); one type or two or more types selected from benzyl alcohol, vanillin, propylene carbonate, and ?-butyrolactone; and one type or two or more types selected from a thioglycolic acid salt, a thiolactic acid salt, cysteine and cysteamine, and a reaction solution (B) comprising an oxidizing agent. (In the formula, R1, R2, R3, R4, R6, and R7 independently represent a hydrogen atom, a hydroxy group, or a methyl group; either one or both of R6 and R7 is/are a hydroxy group; R5 represents a hydrogen atom, a hydroxy group, a galloyl group, or a saccharide; and X represents >CH2, >C?O, or >CHOH.

Abstract: The present disclosure describes a topical composition, and related masks comprising the compositions disclosed herein, for applying to skin for treating acne or skin rejuvenation, the compositions comprising a light activated enzymatic extract; adaptogenic Baobab (Adansonia digitata) seed extract; adaptogenic wild indigo (Tephrosia purpurea) extract; pre- and/or pro-biotic extracts; and a carrier. The mask may be embodied in, or comprise, a hydrogel matrix or a biocellulose material or other fibrous material.

Abstract: The present invention relates to an oil-in-water emulsion comprising a glycopyrronium salt and an emulsifier system comprising at least one macrogol glycerol fatty acid ester, at least one glycerol fatty acid ester and at least one fatty alcohol. Moreover, the present invention relates to such an emulsion for use as a medicament, in particular for treating and preventing diseases in conjunction with excessive sweating. In addition the present invention relates to the non-therapeutic use of such an oil-in-water emulsion for topical application on the skin of a mammal in order to reduce sweating.

Abstract: A robust sunscreen composition is disclosed herein comprising a water soluble polymer and a water insoluble film former providing a synergistic effect in SPF retention and critical wavelength after immersion in water, salt water, and chlorinated water. The water soluble polymer comprises poloxamer 338 (and) PPG-12/SMDI copolymer, poloxamer 407 (and) PPG-12/SMDI copolymer, or a combination thereof.

Abstract: A hair care composition having a combination of a high melting point wax to provide a hydrophobic film (frizz resistance) and thermo-pliable film (heat styling response), along with a lightweight conditioner, to produce a hair care composition that is far less susceptible to buildup than traditional products currently marketed.

Abstract: A process for preparing a potent plant based active, the process includes creating a plant salt, a plant tincture, and a plant essential oil and adding the salt either alone or with the essential oil and/or tincture to a cosmetic product as an active ingredient.

Abstract: Disclosed are methods useful for the topical therapeutic treatment of skin malignancies including skin cancers and cutaneous metastases using compositions containing nanoparticles of paclitaxel or other taxanes.

Abstract: The present invention provides an ophthalmic gel and a preparation method thereof. The ophthalmic gel comprises: an antibiotic; a nanocarrier, wherein the nanocarrier is used to load the antibiotic; and a biodegradable matrix, wherein the biodegradable matrix is compatible with the nanocarrier to carry the nanocarrier. When the ophthalmic gel of the present invention is applied to the surface of the cornea and conjunctiva of the eyes, the biodegradable matrix is automatically degraded and the nanocarrier carried by the biodegradable matrix will slowly release the antibiotic, loaded in the nanocarrier, at an appropriate rate to overcome the high-frequency use of general ophthalmic drugs and easily caused blurred vision; the present invention further comprises an ophthalmic gel preparation method.

Abstract: The present disclosure provides a once-daily water-soluble pharmaceutically active formulation for oral administration. In certain embodiments, the composition comprises a watersoluble pharmaceutically active organic compound incorporated into a small particulate, each particulate having a core of the water-soluble pharmaceutically active organic compound or an acceptable salt thereof in reversible association with a pharmaceutically acceptable drug-binding polymer. The core of the composition being surrounded by an insoluble water permeable membrane that is capable of delaying the dissolution of the pharmaceutically active compound therewithin and providing for extended release of the pharmaceutically active compound.

Abstract: A chewing gum for mucosal delivery of cannabinoids, the chewing gum being formulated as an extruded chewing gum including water-soluble chewing gum ingredients mixed into water-insoluble gum base, wherein the chewing gum has one or more cannabinoids, and wherein the chewing gum generates saliva and delivers at least 10% by weight of the one or more cannabinoids to the oral mucosa during the first 5 minutes of chewing.

Abstract: Disclosed herein is a particle delivery system comprising electrospun nanofiber comprised of coaxial fiber with a microfluidic core. Iron-doped apatite nanoparticles (IDANPs) have demonstrated a unique influence over phage killing of bacteria, whereby, IDANP-exposed bacterial cultures experience 2× the bacterial death as controls. IDANPs consist of hydroxyapatite (HA) doped with iron. HA is a mineral known to be biocompatible and analogous to the inorganic constituent of mammalian bone and teeth and has been approved by the Food and Drug Administration (FDA) for many applications in medicine and dentistry. Previous work has shown that for IDANPs to enhance antibacterial activity of phage to the greatest extent, bacterial cultures should be exposed to IDANPs for 1 hr prior to phage introduction. Biocompatible polymer materials which encase IDANPs and/or phage can be used to disseminate IDANPs and/or phage in a controlled manner into a physiological system for treatment of bacterial infection.

Abstract: The application relates to an aqueous pharmaceutical formulation for use in the treatment of Type I or Type II Diabetes Mellitus, wherein the treatment reduces the risk of nocturnal hypoglycemia, said formulation comprising 200-1000 U/mL [equimolar to 200-1000 IU human insulin] of insulin glargine, with the proviso that the concentration of said formulation is not 684 U/mL of insulin glargine.

Abstract: A method for continuously processing at least two liquid feed streams is provided. A system for continuously processing at least two liquid feed streams is also provided.

Abstract: The present invention relates to a branched peptide that includes a first peptide chain and a second peptide chain having its C-terminal amino acid covalently linked to a sidechain of an amino acid residue of the first peptide chain, wherein the first peptide chain includes a plurality of aromatic amino acids and, optionally, an aromatic group linked to an amino terminus of the first peptide chain; and the second peptide chain includes a plurality of hydrophilic amino acids and an enzyme cleavage site. Pharmaceutical compositions containing the branched peptide and one or more therapeutic agents in an aqueous medium are disclosed, where the branched peptides form micelle structures in the aqueous medium. Methods of using the pharmaceutical composition to deliver therapeutic agents, and for treating various disease conditions are also described.

Abstract: Methods and devices for producing a population of liposomes are provided. Aspects of the methods include applying a centrifugal force to a suspension of liposomes in a manner sufficient to pass the liposomes through a porous membrane to produce a population of liposomes. Aspects of the invention further include devices, systems and kits useful for performing the methods.