Abstract: Embodiments of the invention provide compositions useful in analyte sensors as well as methods for making and using such compositions and sensors. In typical embodiments of the invention, the sensor is a glucose sensor comprising an analyte modulating membrane formed from a polymeric reaction mixture formed to include limiting amounts of catalyst and/or polycarbonate compounds so as to provide such membranes with improved material properties such as enhanced thermal and hydrolytic stability.

Abstract: Blood sampling device comprising a lancet body supporting a lancet tip, said lancet being moveably mounted within a housing, an urging member configured to urge said lancet forwardly in said housing in use from a primed position in which said lancet tip is located within a passage to a lancing position in which said lancet tip projects through an aperture in the forward end of the housing and a removable safety cap.

Abstract: A neurotransmitter imbalance detection system (SYS) is disclosed, said system (SYS) comprising at least one eye movement sensor (SEN) for sensing movement of a closed eye (EYE), a frequency analysis arrangement (FAA), and wherein said eye movement sensor (SEN) is configured to output at least one eye movement signal (EMS) representing movement of the closed eye (EYE) and to communicate said at least one eye movement signal (EMS) to said frequency analysis arrangement (FAA), wherein said frequency analysis arrangement (FAA) is configured to receive said at least one eye movement signal (EMS) and process said at least one eye movement signal (EMS) by frequency analysis to determine a frequency distribution. Also, methods for identifying eye movement patterns, for detecting a neurotransmitter imbalance, for identifying a psychiatric disorder, and for treating a psychiatric disorder are disclosed.

Abstract: Disclosed is a system for detecting an emotional state of a companion animal, including: a state information collecting device comprising a microphone and sound sensor which collects a sound of the companion animal, a temperature sensor which collects a temperature of the companion animal, and an acceleration sensor which collects an activity of the companion animal, the state information collecting device being worn on a body of the companion animal; and a companion-animal emotion analysis server configured to extract characteristic information of sound information of the companion animal transmitted from the state information collecting device, select emotional state information of the companion animal corresponding to the extracted characteristic information from a database, and transmit the selected emotional state information of the companion animal through a wireless communication network to a portable terminal of an animal guardian.

Abstract: An analysis system includes a storage unit and a processing unit. The processing unit quantifies the brain state on the basis of occurrence frequencies of the duration included in a plurality of regions each of which has a predefined range within which the duration falls. The calculated brain index is calculated by the processing unit using coefficients.

Abstract: A technique for enabling efficient retrieval of a digital representation of personality data of a user (402) by a client device (406) from a server (404) is disclosed, wherein the digital representation of the personality data is processed at the client device (406) to provide a user-adapted service to the user (402). A method implementation of the technique is performed by the server (404) and comprises storing a neural network being trained to compute personality data of a user based on input obtained from the user (402), receiving, from the client device (406), a request for a digital representation of personality data for a user (402), and sending, to the client device (406), the requested digital representation of the personality data of the user (402), wherein the personality data of the user is computed using the neural network based on input obtained from the user (402).

Abstract: Dry electrodes are electrodes for attachment to human skin without skin preparation or the use of electrolyte gels. The electrode includes a substrate, electrically conductive particles with at least one point, in contact with the substrate, a supporting layer that envelopes the electrically conductive particles with points that protrude from the supporting layer, and an electrical connector. Some electrodes have an electrically conductive substrate, other electrodes have an electrically conductive supporting layer.

Abstract: Example implementations include a device with an electrode electrically responsive to presence of a biochemical present within a biofluid, and one or more biofouling and interferent mitigation layers disposed on the electrode to block transmission of biofouling agents to the electrode and the reaction of interferents on the electrode. Example implementations also include a method of obtaining a biofluid sample, mitigating a biofouling characteristic associated with the biofluid sample, and obtaining a biochemical characteristic associated with the biofluid sample.

Abstract: Embodiments of the present invention (herein referred to simply as “the invention”) comprise an EEG monitoring device worn on or around a user's ears. In some embodiments of the invention, the device comprises a flexible printed circuit containing EEG sensors, skin adhesives or adhesive sensors, and a flexible extension to position the sensor adjusting the user's head size. The device may be designed so that when worn by a user, the sensors are placed at specific points on a user's head in order to accurately capture electroencephalography signals. Said specific points may be one or more points of a 10-10 EEG system. The EEG sensors may comprise or may be made of an adhesive material.

Abstract: A method and apparatus of mapping efficiency by suggesting map points location includes receiving data at a machine, the data including a plurality of signals received during the performance of a triangulation to locate a focal tachycardia, generating, by the machine, a prediction model as to the location of the focal tachycardia, and modifying, by the machine, the prediction model based upon additional data received by the machine.

Abstract: A method includes receiving (a) multiple electrophysiological (EP) signals acquired by multiple catheter electrodes in contact with tissue in cardiac chamber region, and (b) respective tissue locations at which the EP signals acquired. Selecting first and second electrodes, positioned at first and second respective tissue locations of first and second respective sections of the region. Based on the acquired EP signals, calculating: (i) local activation time (LAT) values for the first and second respective tissue locations, (ii) first and second average LAT values for the first and second sections, respectively, and comparing the first and second average LAT values. Determining first and second representative locations are within the first and second sections, respectively.

Abstract: A frequency encoded source imaging system includes an EEG or MEG sensor array and a processing system for analyzing the signals from the sensor array in at least two different frequency bands, where the analysis is localized with respect to a three-dimensional grid corresponding to the portion of the human body.

Abstract: Embodiments of the present disclosure provide an apparatus, method and system for physical, pre-action, extremity and related spinal cord, brain stem and neural therapies. An apparatus according to the present disclosure can include: a computing device configured to convert an input control action into a simulation instruction, wherein the input control action is provided by an input device; at least one simulated extremity operatively connected to the computing device and configured to simulate at least one modeled human anatomical movement based on the simulation instruction, wherein the at least one modeled human anatomical movement is distinct from the input control action; and a feedback device operatively connected to the computing device and configured to transmit a sensory response, wherein the sensory response is based on the modeled human anatomical movement.

Abstract: Systems and methods for detecting a cognitive diseases and/or impairments in humans are disclosed. The method may include providing a saliva sample from a human subject, and subjecting at least a portion of the saliva sample to a spectroscopic analysis to produce a sample spectroscopic signature. The method may also include analyzing the produced sample spectroscopic signature using a predetermined statistical model. The predetermined statistical model may be based on spectroscopic signatures for a plurality modeling samples, and the spectroscopic signatures for each of the plurality of modeling samples may be associated with one of a plurality of predetermined cognitive categories. Additionally, the method may include correlating the produced sample spectroscopic signature with one of the plurality of predetermined cognitive categories based on the spectroscopic signatures for each of the plurality of modeling samples of the predetermined statistical model.

Abstract: This disclosure relates to an epileptic seizure predicting device (1) that executes a seizure predicting process (12). The seizure predicting process (12) includes: a process of providing, as input data, electrocardiographic index data generated from an electrocardiographic signal of a subject, to an autoencoder (AE) that has been provided with and has learned with, as learning input data, learning electrocardiographic index data generated from an electrocardiographic signal of an epilepsy patient, and obtaining output data which is reconstruction data of the input data; a process of calculating an error between the input data and the output data of the subject; and a detection process of detecting a sign of an epileptic seizure of the subject on the basis of whether or not the error exceeds a management limit that the error should not exceed in a case of a seizure-free interval of epilepsy.

Abstract: Described herein are systems and methods for determining medical staffing requirements for administering OIT to patients. Specifically, the methods and systems disclosed herein can determine the time required by a medical staff at a given treatment location to devote to administering OIT to patients as well as the number of patients undergoing OIT over a selected time period. The methods and systems disclosed herein can further provide the time required by providers and clinical staff at a given treatment location to devote to administering OIT to patients.

Abstract: Digital imaging systems and methods are described for analyzing pixel data of an image of a skin area of a user for determining skin laxity. A plurality of training images of a plurality of individuals are aggregated, each of the training images comprising pixel data of a respective skin area of an individual. A skin laxity model, trained with the pixel data, is operable to output, across a range of a skin laxity scale, skin laxity values associated with a degree of skin laxity. An image of a user comprising pixel data of at least a portion of a user skin area is received and analyzed, by the skin laxity model, to determine a user-specific skin laxity value of the user skin area. A user-specific electronic recommendation addressing at least one feature identifiable within the pixel data is generated and rendered, on a display screen of a user computing device.

Abstract: Digital imaging systems and methods are described for analyzing pixel data of an image of a shaving stroke for determining pressure being applied to a user's skin. A plurality of training images of a plurality of individuals are aggregated, each of the training images comprising pixel data of a respective individual when shaving with a shaving razor. A pressure model, trained with the pixel data, is operable to determine pressure being applied to the respective individual's skin. An image of a user when shaving with the shaving razor is received and analyzed, by the pressure model, to determine a user-specific pressure being applied to the user's skin by the shaving razor when a user shaving stroke is taken. A user-specific electronic recommendation to address at least one feature identifiable within the pixel data is generated and rendered, on a display screen of a user computing device.

Abstract: Aspects relate to a portable device that may be used to identify a critical intensity and an anaerobic work capacity of an individual. The device may utilize muscle oxygen sensor data, speed data, or power data. The device may utilize data from multiple exercise sessions, or may utilize data from a single exercise session. The device may additionally estimate a critical intensity from a previous race time input from a user.

Abstract: A sample collector is provided for receiving a breath gas sample and a gas sample testing device is provided with such a sample collector. The sample collector is configured for receiving from a person a breath gas sample to be investigated. The sample collector includes an inflow part (2) with an inflow opening (IO) and an outflow part (13) with an outflow opening (OO). The sample collector provides a flow duct guiding a gas sample from the inflow opening (IO) to the outflow opening (OO). The inflow part (2) is rigidly connected with the outflow part (13). The inflow part (2) and the outflow part (13) together form a housing which gas-tightly surrounds the flow duct. The inflow part (2) tapers in a direction towards the outflow opening (OO). The outflow part (13) tapers in a direction towards the inflow opening (IO).

Abstract: This disclosure is directed to devices, systems, and techniques for determining an efficacy of a treatment program. For example, a medical device system includes a medical device including one or more sensors configured to generate a signal that indicates a parameter of a patient. Additionally, the medical device system includes processing circuitry configured to receive data indicative of a user selection of a reference time; determine a plurality of parameter values of the parameter based on a portion of the signal corresponding to a period of time including the reference time. Additionally, the processing circuitry is configured to identify, based on a first set of parameter values, a reference parameter value, calculate a parameter change value, and determine, based on the parameter change value, whether an improvement or a worsening of the patient has occurred responsive to a treatment administered beginning at the reference time.

Abstract: Medical devices coupled to a sensor, and systems including such devices, can generate data and analysis based on that data, which may be used to identify and/or address problems associated with the implanted medical device, including incorrect placement of the device, unanticipated degradation of the device, and undesired movement of the device. Also provided are medical devices coupled to a sensor, and devices and methods to address problems that have been identified with an implanted medical device.

Abstract: Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods include evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.

Abstract: A garment worn by a user includes a sensor material that includes a) an insulating material stretchable in a longitudinal direction and b) a conductive fiber having conductivity and coiled around the insulating material, and a plurality of connecting portions electrically connected to three or more portions of the conductive fiber, wherein at least a portion of the conductive fiber includes a fixing region fixed such that the fixing region does not stretch or shrink even when the insulating material stretches and shrinks, and at least two connecting portions of the plurality of connecting portions are electrically connected to each of two different portions of the fixing region.

Abstract: A system for measuring cardiovascular data includes an elongate member having a channel, a first expandable member carried by the elongate member and movable between a collapsed state and an expanded state by adjustment initiated externally of a subject, a first sensor disposed on a surface of the elongate member, second and third sensors disposed on a surface of the first expandable, a first optical sensor located at a first location in relation to the distal end of the elongate member and configured for obtaining photoplethsmographic data, and wherein the first expandable member in its expanded state is configured to interface with the subject's larynx for delivery of at least oxygen gas into the respiratory system of the subject, and the second and third sensors are configured to contact tissue in proximity to the larynx when the first expandable member is in its expanded state.

Abstract: A multi-modal monitoring system is provided for monitoring activity of an individual. The monitoring system is configured as a computer system comprising data input, memory and a data processor. The data processor is configured and operable to receive and analyze first and second measured data concurrently collected from the individual and corresponding to, respectively, detected brain signals indicative of movement planning by the individual, and detected motion signals indicative of actual movement recognition by at least one body portion of the individual. The data analysis includes applying a multi-modal processing to the first and second measured data to decode the brain and body signals, and upon identifying that the decoded brain and body signals satisfy a condition of common decoded motor commands, generate a control signal indicative of the individual's intended physical action, which can be used for controlling operation of an execution device or assistance device(s), or for providing biofeedback.

Abstract: Devices, systems, and methods of mapping a vessel system of a patient and identifying lesions therein are disclosed. This includes a method of evaluating a vessel of a patient, the method comprising obtaining image data for the vessel of the patient, obtaining physiological measurements for the vessel of the patient, co-registering the obtained physiological measurements with the obtained image data such that the physiological measurements are associated with corresponding portions of the vessel of the patient, analyzing the co-registered physiology measurements to determine a classification of a lesion within the vessel of the patient, and outputting, to a user interface, the classification of the lesion. Other associated methods, systems, and devices are also provided herein.

Abstract: A method for determining a prediction model for predicting, from an N-uplet of markers Mn, the value of a K-uplet of markers Mk to assist the prognosis of central nervous system pathologies, the method including for each subject of a plurality of subjects, a step of acquiring, at a time TO, an N-uplet of markers Mn, to obtain a plurality of N-uplets of markers Mn; for each subject of the plurality of subjects, a step of acquiring, at a time T* greater than or equal to TO, a K-uplet of markers Mk, to obtain a plurality of K-uplets of marker Mk; and a step of determining, from the plurality of N-uplets of markers Mn and the plurality of K-uplets of markers Mk, a prediction model for associating with any N-uplet of markers Mn acquired at a time T, a K-uplet of marker Mk at a time T+?T with ?T=T*?TO.

Abstract: An estimation apparatus acquires stance phases of both feet and estimates a risk of abnormality of a lower limb on the basis of the difference between the stance phases of the both feet.

Abstract: A determination apparatus acquires a feature amount of a whipping motion of a foot and determines a gait disorder risk on the basis of the feature amount.

Abstract: A risk estimation apparatus includes a data acquisition unit that acquires measured data of foot pressures of the left foot and the right foot obtained by sensors that are provided in shoes and measure the foot pressures, a stance phase identification unit that identifies a starting timing and an ending timing of a stance phase of each of the left foot and the right foot from the measured data of the foot pressures, and a risk estimation unit that estimates a risk of abnormality of a lower limb on the basis of asymmetry between the foot pressures of the left foot and the right foot during the stance phase.

Abstract: Disclosed are systems and methods for generating graphical displays of analyte data and/or health information. In some implementations, the graphical displays are generating based on a self-referential dataset that are modifiable based on identified portions of the data. The modified graphical displays can indicate features in the analyte data of a host.

Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.

Abstract: A basal metabolism estimation device includes: at least one memory configured to store instructions; and at least one processor configured to execute the instructions to: acquire first measurement data related to a left foot and second measurement data related to a right foot; identify a starting timing and an ending timing of a stance phase of each of the left and right feet based on the first and second measurement data; calculate a stride time for one cycle of movement of one of the feet during walking and a degree of asymmetry between the first measurement data in the stance phase of the left foot and the second measurement data in the stance phase of the right foot; and estimate basal metabolism based on the stride time and the degree of asymmetry.

Abstract: There is provided a method and apparatus for determining respiratory information for a subject. One or more physiological signals indicative of at least one physiological characteristic of the subject is acquired (202) and contextual information relating to at least one of the subject and the one or more physiological signals is obtained (204). Based on the contextual information, at least one signal processing algorithm for each of the one or more physiological signals is selected (206), the at least one signal processing algorithm being adapted to determine respiratory information. Respiratory information for the subject is determined based on the one or more physiological signals using the at least one signal processing algorithm selected for the one or more physiological signals (208).

Abstract: Extended field-of-view imaging is enabled by combined imaging with a kilovolt (“kV”) x-ray source and a megavolt (“MV”) x-ray source, in which at least one of the corresponding x-ray detectors is laterally offset from the target isocenter by an amount such that the x-ray detector does not have a view of the target isocenter. This scan geometry enables the reconstruction of non-truncated images without resorting to the more expensive solution of outfitting the imaging or radiotherapy system with enlarged x-ray detectors.

Abstract: An embodiment of a computed tomography apparatus includes an x-ray source and scan control circuity configured to control the x-ray source to expose a subject with x-rays over a scan having a plurality of views. A detector is disposed to receive x-rays from the x-ray source, has a plurality of anodes arranged in groups, and a common conductive strip between the anodes. Photon counting circuits are respectively provided for each of the anodes and have adjustable operating parameters. Connection circuitry is configured to adaptively connect, in a first mode, each anode to one of the photon counting circuits and, in a second mode, each anode in a group to a same one of the photon counting circuits. Processing circuitry, connected to the connection circuitry and the photon counting circuits, is configured to, for each of the views, select the first mode or the second mode and adjust the operating parameters based upon exposure data obtained from exposing the subject with the x-rays from the x-ray source.

Abstract: X-ray detectors for generating digital images are disclosed. An example digital X-ray detector includes: a scintillation screen; a reflector configured to reflect light generated by the scintillation screen; and a digital imaging sensor configured to generate a digital image of the light reflected by the reflector.

Abstract: A medical image diagnosis apparatus according to an embodiment includes an ultraviolet light source, processing circuitry, and an imaging equipment. The ultraviolet light source emits an ultraviolet ray. The processing circuitry controls irradiation of the ultraviolet ray to an irradiation object irradiated with the ultraviolet ray in an examination room by moving a position of the ultraviolet light source relatively with respect to the irradiation object. The imaging equipment acquires a medical image of a subject.

Abstract: A radiography system includes an image former, a first determiner, and an operation controller. The image former performs serial radiography of repeatedly generating a frame that constitutes a video. The first determiner determines whether a next test action is the serial radiography. The operation controller makes the image former begin turning a switch element on/off in a same manner as a manner in the serial radiography before start of the next test action in a case where the first determiner determines that the next test action is the serial radiography.

Abstract: A method for calculating a coronary artery calcium score, the method comprising acquiring a target image for a coronary artery and myocardium before contrast enhancement, identifying the coronary artery included in the target image by using an artificial neural network, calculating a coronary artery calcium score based on the identified coronary artery, wherein the artificial neural network is trained based on a training database generated via alignment between a pre-acquired image of a coronary artery and myocardium before contrast enhancement and a pre-acquired image of a coronary artery and myocardium after contrast enhancement.

Abstract: A core-line extraction unit extracts a core line of the blood vessel from a three-dimensional image of a subject including the blood vessel. A local-route extraction unit extracts a local route of the core line within a predetermined range based on a reference point on the core line. In a case where a plurality of points on the local route are projected, a plane setting unit sets a plane having an orientation in which a distribution of a plurality of the projected points has a reference value based on a maximum value of the distribution, as a display plane of the three-dimensional image.

Abstract: A multimodal imaging apparatus, comprising a rotatable gantry system positioned at least partially around a patient support, a first source of radiation coupled to the rotatable gantry system, the first source of radiation configured for imaging radiation, a second source of radiation coupled to the rotatable gantry system, the second source of radiation configured for at least one of imaging radiation or therapeutic radiation, wherein the second source of radiation has an energy level more than the first source of radiation, and a second radiation detector coupled to the rotatable gantry system and positioned to receive radiation from the second source of radiation, and a processor configured to combine first measured projection data based on the radiation detected by the first detector with second measured projection data based on the radiation detected by the second detector, and reconstruct an image based on the combined data, wherein the reconstructing comprises at least one of correcting the second meas

Abstract: A timer circuit for an X-ray imaging system having an X-ray generator used to generate images of a patient. The circuit includes a current sensor connected between a main power system and a circuit interrupter, wherein the circuit interrupter is also connected to the X-ray generator. The circuit also includes a timing device coupled between the current sensor and a control computer. The timing device is triggered when a current level detected by the current sensor exceeds an idle current level wherein X-rays are not generated by the X-ray generator. The timing device then measures a time period that the idle current level is exceeded. When the measured time period exceeds a predetermined time period by 10%, the circuit interrupter is activated to turn off current flow to the X-ray generator.

Abstract: An integrated imaging and device deployment platform and method may include a catheter, at least one imaging unit, at least one deployment unit, and at least one device configured to be deployed by the at least one deployment unit. The integrated imaging and device deployment platform facilitates improved navigation and deployment of a therapeutic or medical device by providing the at least one imaging unit proximate the deployment unit. Information generated from the at least one imaging unit may be utilized with additional imaging modalities to provide improved imaging and delivery of devices while reducing use of X-ray radiation and contrast injection.

Abstract: A device and system for and methods of using an ultrasound probe housing containing ultrasound probes configured to produce images inside the body of a patient for procedures requiring needle or probe insertion. The ultrasound probe housing can be configured with a guide channel cut-out or aperture between the ambient side and body side of a patient. A needle guide assembly may be pivotally connect internal to the guide channel cut-out or aperture of the ultrasound probe housing at a pivot point such that during use the needle enters the patient through the needle guide assembly within the ultrasonic probe housing so that the needle can be visualized by the ultrasonic probes in real time. The ultrasound probe housing may also provide an adhesion or suction quality to the body side of the device to facilitate aspects of the invention.

Abstract: A self-contained ultrasound patch assembly for detecting fluid flow in a vessel includes piezo elements that can transmit ultrasonic energy and detect echo signals. A flex module has two support portions connected to respective ones of the elements with a hinged portion coupled to the support portions, allowing them to be positioned angularly relative to each other. Electronics that direct the elements to transmit ultrasonic energy and process detected echo signals are in communication with the elements through the flex module. A transducer frame includes an alignment portion engaging a flex module alignment portion to retain the flex module in an aligned position. The frame supports the elements at a fixed angular position with respect to each other. A housing encloses the electronics and frame, and fixedly retains the frame to position the elements to transmit toward a bottom surface and away from a top surface of the housing.

Abstract: A system is described for conducting an ultrasound scan on a human subject. The system includes an ultrasound probe generating ultrasound image data and provisioned with one or more position sensors generating real time position and orientation data as to the position of the ultrasound probe and orientation in three-dimensional space during use of the probe; one or more machine learning models trained to correlate ultrasound images with probe position and orientation, wherein the one or more machine learning models receive images generated from the ultrasound probe; a feedback generator generating feedback data based on the current probe position determined by the position sensors; and a feedback display receiving the feedback data providing real-time suggestions to the user of the ultrasound probe for adjusting the probe position, orientation, pressure and/or other parameters of the ultrasound probe to improve the quality of the images generated from the ultrasound probe.

Abstract: Various methods and systems are provided for a guided at-home ultrasound imaging session. In one example, a system for ultrasonically scanning a tissue sample includes a hand-held ultrasound probe including a transducer array of transducer elements, a probe position tracking device including one or more position sensors coupled to the ultrasound probe, and a controller. The controller is configured to, during an imaging session, determine a position of the ultrasound probe relative to a target position based on position data collected by the probe position tracking device, and responsive to an indication that the ultrasound probe is at the target position, acquire image data with the transducer array.

Abstract: A multi-row ultrasonic imaging apparatus and an ultrasonic imaging instrument are disclosed. The multi-row ultrasonic imaging apparatus includes a housing, and a first ultrasonic transducer, a second ultrasonic transducer, and an adjustment mechanism that are installed in the housing. Ultrasonic waves emitted by the first ultrasonic transducer and the second ultrasonic transducer can intersect to form a confocal point. At least one of the first ultrasonic transducer and the second ultrasonic transducer is connected to the adjustment mechanism to move relative to the housing under the action of the adjustment mechanism, so as to adjust the position of the confocal point.