Abstract: Methods and apparatuses for recognizing a gait task, that may detect a gait pattern of a user based on sensed data, generate a gait feature of the gait pattern based on similarities between the gait pattern and similar gait data extracted from each of a plurality of databases, and estimate a gait task corresponding to the gait pattern by applying the gait feature to a desired learning model, may be provided.

Abstract: Multipurpose tactile warning panels for use in pedestrian walkways, and in particular tactile warning panels that are designed and built with multifunction/multipurpose capabilities that serve the visually impaired and enable the deployment of smart city technology by integrating tactile warning systems and subsurface enclosures that can withstand pressures of five (5) tons up to and exceeding sixty (60) tons and incorporate small cells, beacons, sensors, Fog Computing, electric energy generation, rechargeable power supplies, wireless M2M communication and a plethora of other smart city technologies.

Abstract: A method and apparatus for massage therapy is described. The method may include using the apparatus to apply heat and pressure to a subject's body. The apparatus may include a handle, a stem connected to the handle, a pusher tip connected to the stem, and an electric heating element configured to increase the temperature of the pusher tip. The heating element may be used to heat the pusher tip so that a precise amount of heat and pressure may be applied to a subject's body during massage therapy.

Abstract: Creating a replica of an anatomical structure. At least some of the example embodiments are methods including: accepting a plurality of pictures of the anatomical structure of a subject; creating an object file that contains an initial model of an outside surface of the anatomical structure; cutting the initial model to a predetermined exterior shape circumscribing the anatomical structure, the cutting creates a positive model of the anatomical structure within the predetermined exterior shape; creating a negative model of the anatomical structure from the positive model; placing a stem tool object on an outside surface of the negative model in relationship to an orifice of the anatomical structure, and thereby creating a final negative model; printing, by way of a three-dimensional printer, the final negative model to create a negative mold; and casting the replica of the anatomical structure using the negative mold.

Abstract: An apparatus for testing and exercising pelvic floor musculature, the apparatus comprising an elongate housing adapted for a pelvic floor aperture. The housing accommodates an oscillator and an accelerometer connected to a signal processor configured for communicating signals representative of values read from the accelerometer. A result is calculated from an applied oscillation and a response measured, and used for characterizing the musculature. In one embodiment the frequency resulting in the greatest response from the musculature is measured, and this frequency is applied during exercise.

Abstract: A hand-held, non-penetrating, non-phallic shaped apparatus for clitoral massage and stimulation comprising a massager housing having a generally prolate spheroid shape sized to fit entirely within a user's palm leaving a user's fingers free, generally convex top and bottom, first and second convex ends, a power source; a vibrating source contained within the massager housing providing at least one level of vibration; at least one switch for activating said vibration; a generally elliptical three-dimensional concave depression on a surface of the convex top of one of said convex ends of sufficient length, width, and depth for enveloping and facilitating the stimulation of a woman's clitoris and labia; wherein when in use the apparatus is held by the bottom.

Abstract: Devices and methods for blood flow enhancement and hemodynamic power monitoring are provided. A blood flow enhancement device includes a pump system configured to be coupled to a central vasculature of a subject during cardiopulmonary resuscitation (CPR). The pump system includes a pumping mechanism configured to increase forward blood flow generated during the CPR while substantially limiting backward blood flow generated during the CPR. The pumping mechanism being operated concurrently with the CPR. The hemodynamic power monitor is configured to control a chest compression device and an active valve.

Abstract: Multi-dose packaged over-the-counter antitussive syrups comprise a bottle containing about 75 ml or less of a liquid formulation of dextromethorphan hydrobromide. The liquid formulation provides at least two doses of dextromethorphan hydrobromide. Multi-dose packaged over-the-counter liquid formulations comprise a bottle having a capacity of about 100 ml or less, at least two doses of the liquid formulation carried within the bottle, a cap, a dosage cup releasably carried on the cap and a shrink wrap substantially enveloping the bottle and the dosage cup. Antitussive syrups comprise water, dextromethorphan hydrobromide in amounts from about 6 to about 25 mg/ml, and sweetener in amounts from about 200 to about 800 mg/ml.

Abstract: A connection assembly for conducting a medical liquid, comprising a connection piece, an attachment part attached to the connection piece; an opening into which the connection piece engages; and a seal element for sealing a passage between the connection piece and the attachment part. The seal element is held between the attachment part and the connection piece and has a sealing head, which closes the opening of the attachment part against the passage of liquid when the attachment part is attached to the connection piece, and a body, which adjoins the sealing head and which can be arranged in the opening at a radial distance to the attachment part.

Abstract: There is featured a grasping facilitator that has one or more of a) to c) as set forth below: a) a combination having an annular core and a plurality of gripping ribs spaced about the annular core, with the core and gripping ribs being formed of an elastomeric material and the ribs extending about an upper part, outer part and bottom part of the core so as to leave an interior region of the core that is aligned radially with respective ribs exposed; b) a pliable collar having a main body with a plurality of ridges separated by concave recesses and a central aperture; c) a tray holder having an aperture or projection that has a configuration designed to conform with at least one of a) and b). There is further featured kit combinations of a) to c) above as well as methods of using and assembling one or all combinations of a) to c).

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a backpack for management of tubing to couple the cartridge to a receiving container. A disposable waste container is contained by the cartridge and the backpack. A syringe holder is provided for use of a syringe as a receiving container to receive a compounded medication.

Abstract: The present invention relates to a device for separating medication packages from a strip of medication packages. The device comprises a cutting base along which the strip of medication packages is to be moved, a circular cutting blade arranged perpendicularly against the cutting base, and an actuator connected to the circular cutting blade and configured to move the circular cutting blade in opposite first and second directions for cutting the strip between two successive medication packages. In the device the actuator is connected to the circular cutting blade with a spring suspension allowing the circular cutting blade to move in opposite third and fourth directions perpendicular to the cutting base.

Abstract: Patients with substance abuse problems may be prescribed regular medication that dulls the positive effects of the substance. However, one of the largest challenges for substance abuse patients is that many do not regularly take their medication as they want to experience the high of the substance. Accordingly, systems and methods have been developed for medication sessions that distract the patient from taking the medicine by incorporating the reminder and other med actions in close temporal proximity.

Abstract: A method for enhancing optical properties of sintered, zirconia ceramic bodies and zirconia ceramic dental restorations is provided. The porous or pre-sintered stage of a ceramic body is treated with two different yttrium-containing compositions and sintered, resulting in sintered ceramic bodies having enhanced optical properties. The enhanced optical properties may be substantially permanent, remaining for the useful life of the sintered ceramic body.

Abstract: A polymerisable dental composite material comprising (i) 70 to 85% by weight of an inorganic filler component comprising at least one dental glass and optionally at least one amorphous metal oxide, (ii) 10 to 30% by weight of at least one monomer comprising 1,3-bis(5?-alkyl-3?,8?-dioxo-2?-aza-4?,7?-dioxa-decyl-9?-en)phenyl and/or 1,3-bis(5?,9?-dialkyl-3?,8?-dioxo-2?-aza-4?,7?-dioxa-decyl-9?-en)phenyl, (iii) 0.01 to 5% by weight of at least one di-, tri-, tetra- or multi-functional monomer not being a urethane (meth)acrylate, (iv) 0.01 to 10% by weight of at least one initiator, of an initiator system and optionally of at least one stabilizer and optionally of at least one pigment, wherein the total composition of the composite material amounts to 100% by weight, and a polymerized composite material having a flexural strength of greater than or equal to 190 MPa and an elastic modulus of 12 to 21 GPa for the production of indirect dentures.

Abstract: Nonwoven and elastomeric substrates having formulations disposed thereon, wherein the formulations have improved compatibility with the substrate, are disclosed herein. More particularly, the formulations can be applied on the substrates without compromising the elastomeric properties and overall integrity of the substrate. Laminated articles using one or more of the nonwoven and elastomeric substrates having the formulations disposed thereon are further disclosed.

Abstract: The invention relates to a cosmetic composition for application in the eye area in the form of a gelatinous emulsion, and to the preparation and use thereof.

Abstract: Disclosed herein is a composition in the form of an emulsion for shaping or altering the shape of hair, such as by straightening hair, wherein the composition contains a reducing agent, a neutralizing agent, at least two fatty substances, a nonionic surfactant selected from alkoxylated fatty alcohols and alkyl(ether)phosphates, optionally a quaternary ammonium compound, and water, wherein the pH of the composition ranges from about 2 to less than about 7. Also disclosed is a process for shaping or altering the shape of hair.

Abstract: The present invention relates to novel oil-in-water pumpable nanoemulsions. The oil phase contains oil selected from the group consisting of triglyceride oil and/or petrolatum as well as C8 to C18 fatty acid; and the aqueous phase contains sulfoalkyl ester and/or amide of fatty acids as emulsifier.

Abstract: The present invention provides a water-in-oil polymeric emulsion composition, including: (a) 25 to 65 wt % of a cross-linked polymer, (b) 15 to 40 wt % of an oil; (c) 1 to 12 wt % of a surfactant; and (d) 1 to 40 wt % of water, wherein (a) the cross-linked polymer is polymerized by using 35 to 85 mol % of a 2-arylamido-2-methylpropane-sulfonic acid totally or partially salified by an alkali metal or ammonium, 15 to 65 mol % of acryloyl morpholine, and 0.005 to 1 mol % of a polyethylenic monomer used as a cross-linking agent.

Abstract: The present invention relates to a capsule comprising a pigment and a method for producing the same. More specifically, the present invention relates to a capsule which comprises therein a pigment inside which is likely to be discolored due to external environment, and thereby can easily crack or break and cause color development when applied to the skin, while isolating the pigment from the external environment, and a method for producing the same.

Abstract: The present invention relates to a process for preparing solid microcapsules comprising the following steps: a) preparation of a composition C1, which is either a composition C1a, comprising a single hydrophobic solid particle, or a composition C1b comprising a plurality of hydrophobic solid particles dispersed in a hydrophilic phase, b) addition with stirring of the composition C1 in a polymeric composition C2 at a temperature Tb, whereby an emulsion (E1) is obtained; c) addition, with stirring, of the emulsion (E1) in a composition C3 at a temperature Tc, whereby a double emulsion (E2) is obtained; d) applying a shear to the emulsion (E2), whereby a double emulsion (E3) is obtained; and e) polymerization of the composition C2, whereby solid microcapsules dispersed in the composition C3 are obtained.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, an anionic polymer, and a basic amino acid, as well as methods of using the same.

Abstract: A method of preparing a zinc citrate-containing oral care composition, the method comprising: (a) adding zinc oxide to a solution of citric acid in a solvent to form a suspension; (b) agitating the suspension until a clear solution is obtained; and (c) adding an additional oral care ingredient to the solution obtained in (b). Also, a method of preparing a zinc citrate-containing oral care composition, the method comprising: (a) adding citric acid to a suspension of zinc oxide in a solvent; (b) agitating the suspension until a clear solution is obtained; and (c) adding an additional oral care ingredient to the solution obtained in (b). In both methods, steps (a) and (b) are carried out at a temperature of from 10° C. to 50° C. and the molar ratio of zinc oxide to citric acid in step (a) is about 3:2.

Abstract: The present invention relates to the use of monosubstiuted urea derivatives of the formula I as self-tanning substance, for increasing melanin synthesis, for improving melanin transport and/or improving the distribution of melanin in suprabasal layers, and to preparations comprising these urea derivatives.

Abstract: This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, fluoride source, and a silica abrasive which exhibits an acid pH when measured as an aqueous slurry as well as to methods of using and of making these compositions.

Abstract: A hair cosmetic comprising the following components (A) and (B) at a mass ratio of component (B) to component (A), (B)/(A), of 0.7 or more and 5.0 or less: (A) an aromatic sulfonic acid having a molecular weight of 300 or less or a salt thereof; and (B) a cationic polymer having a cationic charge density of 4.5 meq/g or more.

Abstract: A method of combatting colour loss from a dyed material, the method comprising the steps of: (1) contacting the material with a composition comprising an electrophilic species selected from aldehydes, succinimidyl esters, and mixtures thereof; (2) contacting the material with a composition comprising a chelating agent and/or a salt of an amine and/or a carboxylic acid.

Abstract: The present disclosure relates to methods for extraction of biomass. Biomass of most interest is that which contains biologically active, extracts suitable for the skin care market. The biomass of interest includes botanicals (plant extracts and bioferments thereof), algae (red, brown, green and red, including bioferments thereof), fungi and even animal extracts (insect, crustacean) origin. Further the use of said extracts in cosmetic preparations prepared by the disclosed method is envisioned.

Abstract: The present invention relates to a novel compound represented by following formula 2 produced by means of marine-derived fungus Penicillium sp. and a composition for improving skin wrinkles, enhancing elasticity and skin whitening using excellent collagen synthesis promoting activity and melanin production inhibitory activity of the novel compound. In formula 2, R1 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R1 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R2 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms. R3 is any one selected from the group consisting of H, OH, COOH, an alkyl having 1 to 6 carbon atoms and an alkoxy having 1 to 6 carbon atoms.

Abstract: A manufacturing method of an ascorbic acid dispersion material includes a heating step of adding an ascorbic acid into a solvent including one or more selected from the group consisting of glycerin, diglycerin, polyglycerin represented by a following formula, and propylene glycol, and heating the ascorbic acid to a predetermined temperature to dissolve the ascorbic acid; a cooling step of cooling a solution with the ascorbic acid dissolved therein at a cooling rate of 5 to 20° C./min until a temperature of the solution reaches 35 to 50° C. to remove heat from the solution; and a growth step of storing the solution after completion of the cooling step at 27 to 38° C. for a predetermined period to promote crystal growth so that the ascorbic acid crystal has a flat plate shape, a thickness of 0.05 to 3 ?m, and an average particle diameter of 50 to 100 ?m.

Abstract: Embodiments herein are directed to moisturizing compositions comprising interpenetrating polymer networks, methods of making moisturizing compositions and methods of using moisturizing compositions.

Abstract: The application describes a cosmetic agent for temporarily reshaping keratin fibres, in particular human hair, comprising a film former and a cosmetic carrier, wherein the film former comprises at least one neutralization product of chitosan with at least one organic acid and at least one non-ionic propylene oxide-modified starch, which cosmetic agent is also substantially free of a fully synthetic film former.

Abstract: The present invention relates to a cosmetic composition and a cleaning and caring product comprising the same, use and application method of the cleaning and caring product. The cosmetic composition comprises: a polymerization product, which is obtained by reacting a system comprising the following components: an anionic polymer, an amphoteric polymer and water, the weight ratio of the anionic polymer to the amphoteric polymer is in the range from 1:100 to 100:1 and the total weight of the anionic polymer and the amphoteric polymer is no less than 0.1 wt %, based on that the amount of the composition is 100 wt %; an optional cationic polymer; an optional active ingredient; an optional additive; and an optional cosmetically acceptable medium.

Abstract: The present invention discloses an organic skin moisturizer, which extends and improves the skin cells. The composition is dermatologically acceptable and is capable of moisturizing skin for at least twelve hours after topical application to skin even after multiple washings of the skin.

Abstract: The present invention provides a stable, aqueous injectable solution comprising epinephrine or its pharmaceutically acceptable salt, a sulfite antioxidant, butylated hydroxyl anisole, an organic acid and a chelating agent, wherein the solution is free of an inorganic acid and an inorganic base. The invention also provides a method of treating the septic shock by intravenous administration of stable aqueous injectable solution comprising epinephrine or its pharmaceutically acceptable salt, a sulfite antioxidant, butylated hydroxyl anisole, an organic acid and a chelating agent, wherein the solution is free of an inorganic acid and an inorganic base.

Abstract: The present embodiments provide compositions, methods, and kits for the treatment or prevention of ocular conditions or maladies via non-invasive liquid depots. In at least one embodiment, the liquid depot is capable of sustained-release delivery of at least one pharmaceutical agent to the eye for days or weeks.

Abstract: The present invention recognizes that medical devices, such as but not limited to contact lenses, can be made having a coating made at least in part using printing technologies to provide drug storage and drug release structures. The coating preferably includes at least one drug reservoir layer and a least one barrier layer, and can include structures, such as but not limited to capillary structures that alone or in combination modulate the release of the drug from the coating. One aspect of the present invention is a medical device that incorporates a drug in at least one coating.

Abstract: A powder preparation for nasal administration containing a particulate of steroid hormones having an average particle size of 50 to 300 ?m as an active ingredient is prepared.

Abstract: The present invention is directed to an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.

Abstract: Coconut oil, coconut oil blends that are high in MCTs such as LouAna® liquid coconut oil, pure MCT oils, Omega-3 oils, cannabidiol (CBD), hemp extract, tree nut oil, macadamia oil, almond oil, cashew oil, avocado oil, docosahexaenoic acid (DHA), fish oil, and/or conjugated linoleic acid (CLA) may be emulsified to create an emulsified oil or blend that may take the form of a creamy shot or a cream substitute. These oils and/or blends may be emulsified using an emulsifier that may be selected from the following: sunflower lecithin, sodium stearoyl lactylate (SSL), acacia gum, beta-cyclodextrin, and combinations of same. By emulsifying these oils/oil blends, a good tasting creamy shot or a cream substitute can be formed.

Abstract: A self-foaming composition is described that includes brimonidine, for a no-rinse topical application. The composition can include: at least one intermediate composition B including a gas-generating agent; at least one intermediate composition A including an agent for activating the gas-generating agent; and brimonidine or one of the pharmaceutically acceptable salts thereof being present in at least one of the intermediate compositions A and B. Also described, is a kit or a single container including a plurality of compartments including such a composition.

Abstract: Embodiments of the present invention are directed to particles having a Bryoid and a HDAC inhibitor for the treatment of latent viral disease.

Abstract: Emulsome compositions comprising phosphatidylcholine, cholesterol, tristearin, and one or more lipophilic bioactive agents such as vinpocetine are provided. The emulsomes may further comprise surface modifications of either [N-(carbonyl-methoxypropylethyleneglycol-2000)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt] (MPEG-DSPE) for peglyation or stearylamine for cationization. Methods of improving brain delivery of lipophilic bioactive agents by intranasally administering such emulsome compositions are also provided.

Abstract: A method comprises preparing initial agent molecules and applying the initial agent molecules to microbes for extracellular vesiculation. Microbial vesicles are generated which contain the initial agent molecules by the microbes. The packaged microbial vesicles are then administered to a host organism. By administering the initial agent molecules as a microbial vesicle package, binding proteins for the initial agent molecules may be co-administered, and cells may uptake numerous initial agent molecules concurrently.

Abstract: The invention provides a method of inducing satiety in a subject comprising a step of orally administering a composition comprising an effective amount of a first agent capable of inducing satiety and of a second agent capable of augmenting the satiety-inducing effect of the first agent. Also disclosed are compositions for carrying out the method and a body weight management system comprising such compositions in combination with a device configured for the collection, storage and/or display of information relating to a subject's response to a predefined therapeutic regimen of orally administering the composition.

Abstract: Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and subsequent iransfection of said target cells, and in certain embodiments are characterized as having one or more properties that afford such compounds advantages relative to other similarly classified lipids.

Abstract: The present invention relates to pharmaceutical composition, comprising certain phosphate binder particles having a certain particle size distribution, a process for the manufacture of the pharmaceutical composition and the use of sucroferric oxyhydroxide having a certain particle size distribution for the manufacture of a pharmaceutical composition.

Abstract: The present invention relates to pharmaceutical composition, comprising certain phosphate binder particles having a certain particle size distribution, a process for the manufacture of the pharmaceutical composition and the use of sucroferric oxyhydroxide having a certain particle size distribution for the manufacture of a pharmaceutical composition.

Abstract: The present invention relates to oral solid dosage forms comprising a plasma kallikrein inhibitor, in particular a solid form (Form 1) of the compound of Formula A. Also provided are methods of preparing oral solid dosage forms comprising the compound of Formula A using Form 1 of the compound of Formula A.