Abstract: An electrophysiology map of a portion of a patient's anatomy can be visualized using an electroanatomical mapping system. The system receives a plurality of electrophysiology data points (e.g., an electrophysiology map), which includes a plurality of electrophysiology signals. The system then creates a distribution (e.g., a histogram) for one or more characteristics of the plurality of electrophysiology signals (e.g., dominant cycle length, regular cycle length, peak-to-peak voltage, fractionation, conduction velocity, or the like). The system then analyzes the distribution to determine a display convention (e.g., a range and scale) for a graphical representation of the characteristic based on, for example, a best-fit shape of the distribution, a skew of the distribution, a range of the distribution, and/or a most dominant value of the distribution. The graphical representation can then be output according to the display convention.

Abstract: In a described example, a method includes identifying, by a processor, negative deflections of at least one unipolar signal representing cardiac electrical activity on a surface of interest during a respective interval of the at least one signal. The method also includes determining, by a processor, an activation time for a last identified negative deflection in the respective interval. The method also includes detecting, by the processor, an instance of late activation based on comparing the activation time to a temporal threshold.

Abstract: A vagus nerve stimulation system for stimulating a vagus nerve in a biological subject, the system including a clip configured to be attached to a tragus of the subject, the clip including opposing arms configured so that a distal end of the arms are biased towards each other and electrodes positioned proximate a distal end of the arms on opposing faces so that the electrodes are urged into engagement with opposing faces of the tragus and a signal generator electrically connected to the electrodes, the signal generator being configured to generate at least one therapy signal that is applied to the vagus nerve within the tragus via the electrodes, to thereby modulate the vagus nerve.

Abstract: The invention discloses an objective and quantitative detection method for amblyopia by electroencephalogram (EEG). The method comprises the following steps: firstly, carry out binocular dichoptic viewing display, then design a visual evoked stimulation paradigm, establish a brain-computer interface platform, build a test interaction interface, next determine an amblyopia EEG quantitative index. By using a suppression coefficient (SI) to describe the binocular suppression relationship, quantify the degree of amblyopia, and finally obtain amblyopia detection result feedback, where the computer interaction interface module presents a final amblyopia detection result to realize feedback of a user. The operation is simple and rapid, the applicability is high, and the indexes are objective and quantitative.

Abstract: A fibrosis measurement device that measures fibrosis of a biological tissue non-invasively includes: a sound wave emitter that performs scanning over a surface of a biological tissue as a measurement object to emit sound waves; an electromagnetic wave receiver that receives an electromagnetic wave generated at each location of a biological tissue irradiated with sound waves; a signal extractor that extracts a signal indicating physical property, based on at least one selected from a group including the amplitude, phase, and frequency of an electromagnetic wave received by the electromagnetic wave receiver; an imaging unit that images signals extracted by the signal extractor; and an area comparison unit that compares the area of a portion of the two-dimensional image in which signals indicating a property are displayed, with an area corresponding to a preset threshold of the strength of the signals.

Abstract: A method for detecting and identifying a patient physiological response includes stimulating, via a stimulating electrode coupled to a patient, one or more nerves of the patient. The method includes recording, via a recording electrode coupled to the patient, a plurality of resultant electrical waveforms. The method includes determining, based on the plurality of resultant electrical waveforms, whether at least a subset of the plurality of resultant electrical waveforms includes a patient physiological response. The determining includes comparing the subset of resultant electrical waveforms of the plurality of resultant electrical waveforms to a model waveform from a database of a plurality of model waveforms. The determining includes determining, based on the comparison, a comparison feature. The comparison feature indicates whether the patient physiological response exists in the subset.

Abstract: The neural health or state of a subject is assessed. A recording is obtained of a compound action potential arising in neural tissue of the subject. The recording is processed to determine whether a profile of the recorded compound action potential is anomalous, such as by exhibiting doublets, peak broadening or deformation, or other anomaly. An indication is output regarding the neural state of the subject based on determined anomalies in the recorded compound action potential.

Abstract: Provided is a method for classifying severe cognitive impairment patients by analyzing electroencephalogram (EEG) data. The method of classifying severe cognitive impairment patients by analyzing EEG data includes a brainwave collection step of collecting EEG data on a plurality of users, a first classification step of classifying the plurality of users into a severe cognitive impairment group or a non-severe cognitive impairment group by analyzing the collected EEG data, a second classification step of classifying users included in the non-severe cognitive impairment group into a normal group or an amnestic mild cognitive impairment (aMCI) group, and a third classification group of classifying users included in the normal group into a within normal limits (WNL) group or a preclinical Alzheimer's disease (AD) group and classifying users included in the aMCI group into a non-AD MCI group or a prodromal AD group.

Abstract: Methods, systems, and devices for menstrual cycle phase identifier are described. A system may be configured to receive physiological data collected over a plurality of days, where the physiological data includes at least temperature data. Additionally, the system may be configured to determine a time series of temperature values taken over the plurality of days where the time series includes a plurality of menstrual cycles for the user. The system may then identify morphological features in the time series and identify menstrual cycle phases in the time series based on the morphological features. The system may cause the graphical user interface to display the identified menstrual cycle phases.

Abstract: The present invention relates to a device for determining intra-abdominal pressure in a subject, comprising an intravaginal ring that is provided with a pressure sensor, means for registering the intra-abdominal pressure value measured by the pressure sensor and means for generating an alert signal when the intra-abdominal pressure exceeds a reference value. The present invention also relates to a method for determining intra-abdominal pressure in a subject, comprising the steps of: a) measuring the intra-abdominal pressure in the vagina by means of a device of the invention, b) comparing the intra-abdominal pressure value measured with a reference value; and c) in case the intra-abdominal pressure value exceeds the reference value transmitting an alert signal to the device that triggers a vibration element in the device or an external device, such as a smartphone or smart watch, to provide a warning to change the subjects behaviour in order to lower the intra-abdominal pressure value.

Abstract: Devices, systems and methods are described herein that enable and make assessments related to pregnancy, including assessments related to a labor-related status such as the onset of true labor. In some embodiments, a pregnancy monitoring system comprises a portable, noninvasive data acquisition device adhered to a patient's skin, comprising at least two electrodes to measure uterine electrical activity, signal processing means, data storage means, and a battery. Systems for notification of the labor-related status are described.

Abstract: A system for treating a joint of a patient includes a treatment head including a probe, a force impulse wave sensor, and a pressure sensor. When the probe is pressed against the joint and reaches a predetermined pressure, the pressure sensor causes a release of current such that the probe delivers a mechanical force impulse to the joint. The force impulse wave sensor is configured to sense a frequency of the mechanical force impulse associated with a treatment point of the joint. The treatment head remains in the same target spot during the pre-test, treatment, and post-test. The system is configured to perform the pretest and post-test analysis of the plurality of treatment points to evaluate improvement of the joint after the treatment. The treatment protocol for the treatment point is modified based on the sensed frequency of the mechanical force impulse from the pre-test at the treatment point.

Abstract: A method of determining a likelihood of presence of at least one type of arthritis in a hand of a patient is provided, the method comprising capturing an image of a hand of the patient, processing the hand image to determine at least one first predictive value indicative of presence or absence of arthritis in the hand based on presence or absence of a plurality of identifiable hand features in the hand image, the identifiable hand features including visible physical hand features that are usable to diagnose arthritis in the hand, receiving patient information from the patient, the patient information comprising a plurality of responses to a plurality of respective questions that are relevant to diagnosing arthritis in the hand, and determining a likelihood of presence of at least one type of arthritis in the hand using the at least one first predictive value and the patient information.

Abstract: Tactile sensing devices, systems, and methods to image a target tissue location are disclosed. When force is applied to the tactile sensing device, voltage data is detected and visualized on a screen, indicating the target tissue location.

Abstract: A surgical system includes at least one light emitter and an array of light sensors disposed at the working end of the surgical instrument, individual light sensors in the array of light sensors adapted to generate a signal comprising a non-pulsatile component. The system also includes a controller coupled to the array of light sensors, the controller including an analyzer configured to determine a curve of the non-pulsatile components of the signals of each of the individual light sensors in the array of light sensors, smooth the curve, calculate a derivative of the smoothed curve; invert the smoothed curve, calculate a derivative of the inverted smoothed curve, take a difference between the derivatives, smooth the resultant curve, estimate zero crossings of the smoothed, resultant curve, apply a signum function to points adjacent each zero crossing, if any, and identify a region of interest, if any, based on the result.

Abstract: In a general aspect, metrics of interest are generated based on motion data and displayed. In some aspects, a method includes obtaining channel information based on wireless signals communicated through a space over a time period by a wireless communication network. The space includes a plurality of locations. The method includes generating motion data based on the channel information. The motion data includes motion indicator values and motion localization values for the plurality of locations. The method further includes identifying, based on the motion data, an actual value for a metric of interest for the time period; identifying, based on user input data, a benchmark value for the metric of interest for the time period; and providing, for display on a user interface of a user device, the actual value for the metric of interest and the benchmark value for the metric of interest.

Abstract: Systems and methods for monitoring sleep are disclosed. According to an aspect, a method includes emitting light into tissue. The method also includes detecting light backscattered from the tissue. Further, the method includes determining a sleep pattern based on the backscattered light.

Abstract: A system, a wearable device, and a method for monitoring a sleep cycle of an infant. The system and/or the wearable device are configured to vary the monitoring rate based on the sleep stages and awake the infant and/or send an alarm when the infant is in a life-threatening condition.

Abstract: The present invention relates to devices, systems and methods for detecting disturbances that may occur during the sleep of a subject.

Abstract: Disclosed are processes and techniques implementable by devices and a drug delivery system to maintain optimal drug delivery for a user according to a user's diabetes treatment plan. The disclosed techniques enable a drug delivery device that received an analyte measurement value from an analyte sensor during a prior cycle time to determine a present analyte measurement value has not been received during a present cycle time. A processor of the drug delivery device may, in response to the determination, initiate an action to obtain the present analyte measure value from another device or an estimate of the present analyte measurement value. Based on an outcome of the initiated action, the processor may calculate a dosage of the drug using the present analyte measurement value or information related to the present analyte measurement value. The drug delivery device may also be operable to output the calculated dosage of the drug.

Abstract: The present invention, in some embodiments thereof, relates to methods and/or apparatus for measuring the effectiveness of a renal denervation treatment. In some embodiments, a method for determining effectiveness of the denervation treatment comprises tracking at least one of arterial wall movement, arterial blood flow rate, arterial blood flow velocity, blood pressure and arterial diameter at one or more selected locations in the renal artery over time, and assessing the effectiveness of said renal denervation treatment according to results obtained by tracking.

Abstract: Systems and methods are provided for determine the fat composition in an organ of interest using a non-invasive health measurement system. The non-invasive health measurement system may include an open magnet NMR apparatus. The NMR apparatus may measure NMR signals in a sensitive volume of a patient. The sensitive volume may coincide with an organ of interest, such as a liver. Systems and methods disclosed herein may provide for separation of the water contribution and the fat contribution to the measured NMR signal. Diffusion based separation, T2 based separation, and T1 based separation may each serve as different methods for separating the water and fat contributions to the signal. Separating the water and fat contributions to the single may allow for computation of a proton density fat fraction which may reflect the fat composition of the organ of interest.

Abstract: The present invention is a holding case for an instrumented intra-oral appliance containing recorded data, which charges the intra-oral appliance while not in use and transmits recorded data to storage for review and analysis. The transferred data may be subjected to downloading, validation, storage, analysis, measuring, database fusion (with for example data from other devices), data output, and data recording. Output may be further transferred to a computer, processor, phone, tablet computer, or other hardware for review by a user or technical, research, medical, or other oversight personnel. The holding case can also send data to the appliance including firmware or other onboard operating instructions. The holding case can include additional features such as custom dentition of the user, UV light, or a visual user interface.

Abstract: Electronic devices embedded in textile materials provide an improved connection of the electronic device with a textile without impairing the movement of a user. An apparatus for processing sensor signals includes an electronic device to process user biometric signals and a plurality of electrically conducting pads. Each pad is connected to an electrically conducting wire contacting a sensor corresponding to a user anatomic region and providing a sensor signal to the electronic device. A textile interface for a wearable fabric has a first and second surface and a porosity providing a fluidic communication between the surfaces. The electronic device, the pads, and the conducting wires are arranged on the first surface and attached to the textile interface. A coating material covers the electronic device and the pads and extends from the first to the second surface so as to fluidically seal the electronic device and the pads.

Abstract: The invention relates to a sensor for a body monitoring system comprising micro-needles for measuring body analyte, characterized in that it comprises a support base, at least one basic support plate, and at least one micro-needle distributed on the basic support plate, the basic support plate being adapted to be fixedly mounted on the support base.

Abstract: A hearing device includes a housing configured to be worn at an ear of a user; an output transducer configured to provide an audio signal to the user; a light source configured to provide light emitted from a light emission area at the housing, the light illuminating an illumination volume extending into tissue at the ear when the housing is worn at the ear; and a first photodetector configured to detect a first light intensity of light arriving from a first acceptance volume extending into tissue at the ear when the housing is worn at the ear such that a part of the emitted light scattered by the tissue into the first acceptance volume is contributing to the first light intensity, the first acceptance volume including a first reception area at the housing having a first distance from the light emission area.

Abstract: Systems and methods are provided for that use noninvasively measured physiologic parameters to predict in real time noninvasively unobservable cardiovascular parameters by employing a one-dimensional arterial tree numerical model calibrated with representative patient data. The numerical model further may be trained and calibrated on a larger database that includes synthetic data using machine-learning algorithms to provide a robust generalized estimator for multiple cardiovascular and hemodynamic parameters.

Abstract: A method for monitoring intoxication of a user, the method including: receiving a set of samples from a body region of a user; generating an intoxication metric based on the set of samples; and providing a notification to the user based on the intoxication metric. The method can additionally or alternatively include: modifying operation of the transdermal alcohol sensing device based on the intoxication metric; determining contextual data; maintaining a hydration level of the transdermal alcohol sensing device; and any other suitable processes. A system for monitoring intoxication of a user including a sensor and a housing. The system can additionally or alternatively include any or all of: an inlet, a fastener, an electronics subsystem, a user device, and/or any other suitable component.

Abstract: The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus.

Abstract: A tissue contact detection system tracks, over time during a surgical procedure, a temperature of a surgical instrument associated with a surgical system used for the surgical procedure. The system determines, based on the tracked temperature of the surgical instrument, that the temperature of the surgical instrument changes from a first temperature to a second temperature that varies from the first temperature by at least a predetermined amount, and determines, based on the determination that the temperature of the surgical instrument changes from the first temperature to the second temperature, that the surgical instrument is in physical contact with patient tissue. The system performs, in response to the determination that the surgical instrument is in physical contact with patient tissue, a mitigation operation configured to mitigate the physical contact of the surgical instrument with the patient tissue.

Abstract: At least one example embodiment relates to a measuring system for measuring bioelectrical signals of a patient, the measuring system comprising a sensor electrode, and a mechanical mounting for the sensor electrode, the mechanical mounting being at least partially compressible and comprising a frame structure and a supporting structure. The mechanical mounting is fastened to a substrate of the measuring system and supports the sensor electrode against the substrate, the supporting structure is arranged beneath the sensor electrode, the frame structure at least partially surrounds the supporting structure, and the supporting structure is configured higher than the frame structure.

Abstract: The present invention provides a system and a method for denoising motion artifacts from vital signs signals comprising steps of receiving one or more reflected signals from at least one subject, generating a time sequence buffer of reflected signals of predefined duration for vital signals processing, source separation and a component selection, and estimating and tracking vital signs of the source separation and a component selection.

Abstract: A method for artifact suppression in a sensed signal includes receiving the sensed signal sensed in a brain of a patient, wherein the sensed signal includes a neural signal and artifacts from a cardiac signal, decomposing the sensed signal into a plurality of components of the sensed signal, determining a first group of components, from the plurality of components, that are correlated with one another, determining an estimate of the cardiac signal based on the first group of components, wherein the estimate of the cardiac signal includes the cardiac signal and components of the neural signal, and generating a denoised neural signal based on the estimate of the cardiac signal and a second group of components of the plurality of components of the sensed signal, wherein the cardiac signal is suppressed in the denoised neural signal, and wherein the second group of components excludes the first group of components.

Abstract: A computer-implemented system (CIS), based on the DenseNet model, for processing and/or analyzing computer tomography (CT) medical imaging input data is described. The CIS contains two or more dense blocks containing one or more modules. Within each dense block, output from preceding modules containing convolutional layers are transmitted to succeeding modules containing convolutional layers, via a gate that is controlled by a predefined or trainable threshold. The CIS also includes transition layers between the dense blocks, operably linked to pairs of consecutive dense blocks in the series configuration. The CIS can be used in a computer-implemented method for enhanced diagnoses of hepatocellular carcinoma, based analysis of one or more CT medical images.

Abstract: Systems and methods for training a signal generation model and generating imputed physiological waveform signals in accordance with embodiments of the invention are illustrated. One embodiment includes a method for measuring physiological waveform signals. The method includes steps for receiving a set of one or more input physiological waveform signals, processing the set of input physiological waveform signals, generating an output physiological waveform signal using a signal generation model, and providing outputs based on the generated output signal.

Abstract: An embodiment of a method for generating training data for use in monitoring a health parameter of a person is disclosed. The method involves receiving a pulse wave signal that is generated from radio frequency scanning data that corresponds to radio waves that have reflected from below the skin surface of a person, wherein the radio frequency scanning data is collected through a two-dimensional array of receive antennas of a wearable device over a range of radio frequencies, extracting features from at least one of the pulse wave signal and a mathematical model generated in response to the pulse wave signal, receiving control data from an optical sensor system of the wearable device, wherein the control data corresponds to a blood pressure of a person wearing the wearable device, and labeling the extracted features with a corresponding blood pressure of the control data to generate training data.

Abstract: In a health monitoring method, a photoplethysmography (PPG) signal of a user within a preset time is obtained. Physiological parameters of the user are calculated according to the PPG signal. An age of the user and reference physiological parameters corresponding to the age are also obtained. Differences between the physiological parameters of the user and the reference physiological parameters are calculated. A health status of the user is determined according to the differences. The method improves the efficiency of health monitoring.

Abstract: A method for analyzing the biomechanical activity of a human subject and the exposure to a biomechanical risk factor in a context of physical activity, which comprises collecting signals from sensors of one or more muscles of the subject, collecting signals representing the movement of the subject, and processing these signals to extract signals representative of the vibratory behavior of the muscle or muscles of the subject. This method also comprises detecting a drift of the vibratory signals in relation to a frame of reference of the vibratory behavior of the muscle or muscles in the context of physical activity, and predicting a physiological break time necessary for the subject's muscles to recover their reference vibratory behavior.

Abstract: A system and method provides a glucose report for determining glycemic risk based on an ambulatory glucose profile of glucose data over a time period, a glucose control assessment based on median and variability of glucose, and indicators of high glucose variability. Time of day periods are shown at which glucose levels can be seen. A median glucose goal and a low glucose line provide coupled with glucose variability provide a view into effects that raising or lowering the median goal would have. Likelihood of low glucose, median glucose compared to goal, and variability of glucose below median provide probabilities based on glucose data. Patterns can be seen and provide guidance for treatment.

Abstract: A plurality of sets of simulated optical inputs that is simulated to travel through an animal model of tissue, thereby generating simulated light transmission data, and corresponding oximetry vales may be used to train a simulated fetal oximetry model to predict, or calculate, oximetry values for subsequently received sets of simulated light transmission data. The simulated fetal oximetry model may be adapted to train an in vivo fetal oximetry model that may be configured to predict, or calculate, fetal oximetry values for subsequently received sets of light transmission data received from an in vivo study of a pregnant mammal and her fetus.

Abstract: A computer-implemented method and a system for analyzing glucose monitoring data indicative of a glucose level, comprising: presenting by a data processing device provided a graphical window on a display device wherein the graphical window comprises a time abscissa axis that defines time units, and a glucose ordinate axis that defines glucose units; receiving a plurality of glucose monitoring values associated with a monitoring time period by the data processing device; segmenting the plurality of glucose monitoring values into a plurality of glucose monitoring traces indicative of the glucose level; defining a reference trace segment; determining the reference trace segment for each of the plurality of glucose monitoring traces; and plotting, for a time window comprising the reference trace segment, the plurality of glucose monitoring traces within the graphical window. Furthermore, a non-transitory computer readable medium is disclosed.

Abstract: An apparatus for non-invasively estimating bio-information is provided. According to one exemplary embodiment, the apparatus may include a bio-signal acquirer configured to acquire a bio-signal; and a processor configured to extract a plurality of characteristic points from the bio-signal, determine internally dividing points of the plurality of characteristic points, and extract feature values from the bio-signal based on the internally dividing points to perform bio-information estimation.

Abstract: A wearable device includes an optical sensor system configured to generate blood pressure data corresponding to a person wearing the wearable device, a backside RF sensor system having an RF front-end including at least one transmit antenna and a two-dimensional array of receive antennas, the RF front-end configured to perform radio frequency scanning across a frequency range, the radio frequency scanning performed using the at least one transmit antenna and the two-dimensional array of receive antennas, a processor configured to generate digital data in response to the radio frequency scanning and to coherently combine the generated digital data across the two-dimensional array of receive antennas and across the range of radio frequencies to produce a pulse wave signal of the person, and means for generating blood pressure values based on the blood pressure data from the optical sensor system and the pulse wave signal from the backside RF sensor system.

Abstract: The system provides a method and apparatus for patient monitoring. In one embodiment, the system comprises beacons located in the patient environment. The beacons may be part of the Medical Internet of Things (MIOT). The patient has a medical wearable that includes fall detection and non-clinical medical monitoring within a geo-fencing perimeter to assure patient safety. The caregivers wear monitoring badges that identify the location, proximity, time management and resources spent for a patient. A central hub base station in the home coordinates and collects the information from the beacons, badges, and medical wearable to deliver information (e.g., via the cloud) for the management of the patient and the caregiver.

Abstract: Compositions and methods for in vivo immunoimaging IL-12 as a marker of IL-12—producing activated antigen presenting cells (APCs) in a subject are provided according to aspects of the present disclosure which include: administering a labeled-antibody conjugate to a subject, wherein the labeled-antibody conjugate includes 1) an antibody or antibody fragment that specifically binds to IL-12, and 2) a detection label conjugated to the antibody or antibody fragment, wherein the detection label is a radionuclide tracer, fluorophore, or nanoparticle, and wherein the labeled-antibody conjugate specifically binds to IL-12; and detecting the presence of the labeled-antibody conjugate in the subject in vivo by imaging. According to embodiments of the present disclosure, the subject is human and the antibody or antibody fragment specifically binds to human IL-12.

Abstract: A collimator is provided for reducing aliasing artifacts in images generated in an X-ray imaging system, such as a computed tomography (CT) imaging system. In one embodiment, a collimator comprises a plurality of high attenuating regions interleaved with a plurality of low attenuating regions, with each high attenuating region having a non-uniform transition profile and configured to be aligned with a respective inactive region of a respective channel of an X-ray detector of an X-ray imaging system. In another embodiment, a CT imaging system, comprising an X-ray source configured to project X-rays towards a patient; an X-ray detector configured to receive attenuated X-rays passing through the patient; and a collimator positioned between the patient and the X-ray detector and configured to non-uniformly attenuate the X-rays, the collimator having bell shaped plates, each of the plates separated by a gap.

Abstract: Apparatus and techniques for blocking radiation in a medical environment are described. In one or more embodiments, a lock-block shield device includes a base that is configured to adhesively couple to an object associated with a patient. In some embodiments, the base includes a lock mechanism for securing a work piece that has a generally tubular shape. A shield that is configured to at least partially block transmission of radiation can be coupled to the base in a releasable manner. For example, a clasp is used to secure the base and shield together. In embodiments, a ball and socket joint couples the shield and base to permit, for example, the shield to pivot and articulate with respect to the base.

Abstract: A bite tray, system, and method for alleviating dental discomfort includes a first mouth guard section, a second mouth guard section, a hinge section, and a channel. Each of first and second mouth guard sections include a first surface, a second surface, an anterior region and a posterior region. The first mouth guard section and the second mouth guard section are adapted to receive the teeth of a subject. The hinge section interconnects first and second mouth guard sections to allow the anterior region of each to open and close with respect to each other. The channel is formed when the first surface of the first mouth guard section and the first surface of the second mouth guard are brought together. The channel is adapted to receive and hold a bite plate of an intra-oral radiographic device.

Abstract: The present invention, which addresses to the field of human and veterinary health, aiming at health security inspection, presents the creation of an unprecedented product, for the generation of radiographic images captured in 3D planar and multiplanar modes (Tomosynthesis) of the thorax, abdomen, skull, facial bones, upper/lower limbs, vertebral column, and the like, in routine and emergency examinations, and triage with the patient in the lying down, upright or sitting position, wherein the positioning movements are manual, motorized, or robotic, without restricting.

Abstract: An estimation device includes at least one processor, in which the processor functions as a learned neural network that derives a result of estimation relating to a bone density of a bone part from a simple radiation image acquired by simply imaging a subject including the bone part. The learned neural network is learned by using, as teacher data, (i) two radiation images acquired by imaging the subject including the bone part with radiation having different energy distributions, (ii) the radiation image of the subject and a bone part image representing the bone part of the subject, or (iii) the radiation image of the subject and a bone density image representing the bone density of the bone part of the subject, and information relating to the bone density of the bone part of the subject.