Abstract: A method and apparatus for positioning a camera to capture images inside a body cavity of a patient during a medical procedure is disclosed. The apparatus includes an insertion tube, a plurality of connected linkages extending from a distal end of the insertion tube, each linkage having a threaded actuator received on a threaded end of a drive shaft extending between the threaded actuator and a proximal end of the insertion tube. The apparatus also includes a camera disposed at a distal end of the plurality of connected linkages. Each connected linkage has at least one associated movement actuated by movement of the threaded actuator in response to rotation of the drive shaft, the associated movements of the connected linkages together operable to facilitate positioning of the camera within the body cavity of the patient.

Abstract: Endoscopes comprising a reusable hand-piece and separable disposable shaft assembly are illustrated and described. The reusable hand-piece includes a housing having an articulation control mounted thereto and an electronics module mounted thereto. The articulation control includes control knobs and concentric drive shafts for articulation. The electronics module includes a battery, a control board, and an optical and/or electrical connector. The separable disposable shaft comprises a housing having an articulation wire actuating assembly mounted thereto and an optical and/or electrical connector mounted thereto. When the housing of the hand-piece and the housing of the separable disposable shaft assembly are joined together, the articulation control engages the articulation wire actuating assembly and the optical and/or electrical connector of the reusable hand-piece engages the optical and/or electrical connector of the disposable shaft assembly.

Abstract: An objective optical system for endoscope consists of a front group having a negative refractive power, an aperture stop, and a rear group having a positive refractive power. The front group consists of a first lens having a negative refractive power and a second lens having a positive refractive power. The rear group consists of a third lens having a positive refractive power, a cemented lens of a fourth lens having a positive refractive power and a fifth lens having a negative refractive power, and a sixth lens having a positive refractive power. A shape of the second lens is a meniscus shape having a convex surface directed toward an image side. The sixth lens is cemented to a plane parallel plate, and the following conditional expressions (1) and (2) are satisfied: 1.0<f3/d6<2.8??(1) 1.7<|f1/f1<10??(2).

Abstract: A method comprises, based on a position of a medical instrument within a patient anatomy, determining, by a control system, whether an obstruction is on a surface of a lens of the medical instrument. The method further comprises, based on a determination that the obstruction is on the surface of the lens, instructing, by the control system, a valve control mechanism to open a valve to release a flow of pressurized fluid through a nozzle of the medical instrument and over the surface of the lens. The valve is configured to control provision of the pressurized fluid.

Abstract: This disclosure relates generally to a container and tube set and methods for fluid delivery, and particularly an integrated container and tube set suitable for use with an endoscope to supply liquids and/or gases to the endoscope. The integrated container and tubes may include a container (e.g., water reservoir) containing a fluid and a gas, and a plurality of tubes integrally formed with the container. The integrated container may include an irrigation supply tube having a first lumen in fluid communication with the fluid, a lens wash supply tube having a second lumen in fluid communication with the fluid, a gas supply tube having a third lumen in operative communication with the gas, and an optional alternative gas supply tube having a fourth lumen in fluid communication with the gas. The lens wash supply tube and the gas supply tube may be formed as a single, multi-lumen tube.

Abstract: An otoscope provides a circular display allowing a compact housing providing improved simultaneous viewing of the display and the patient's ear for improved positioning and stabilization of the otoscope. A recorded image may be rotationally corrected, and non-image data displayed on the screen may be rotationally corrected with the use of an inclinometer.

Abstract: The Self-Orienting Imaging Device and Methods of Use sense the orientation of the handheld imaging, and apply the rotational correction by rotating the image to be displayed. When a scanner is used, the scanning element in the scanner is adjusted, such that the eventual scanning direction remains unchanged referencing the subject anatomy. The self-orienting mechanism for the scanner may be implemented in hardware mechanisms.

Abstract: In some embodiments, an ophthalmic laser system may be provided that does not include a traditional laser console. Instead, the treatment device may be configured to house the treatment light source within the device handle. Additionally, in some embodiments, the handheld treatment device may include a user interface, such as dials and buttons, for adjusting various parameters of the therapeutic light. With certain embodiments, the self-contained handheld treatment device may be operated independent of an AC power source. For example, in some embodiments, the handheld treatment device may be battery powered. Additionally, the handheld treatment device may be disposable or may utilize replaceable distal tips in certain embodiments. Certain embodiments may be particularly designed for transscleral cyclophotocoagulation. Also, treatment guides are provided that may be configured to couple with a treatment device to align the device with a target tissue of the eye.

Abstract: Methods and devices determine an eye strain indicator. In one aspect, an augmented reality (AR) device wearable by a user includes an image sensor and a processor coupled to the image sensor. The processor receives image data from the image sensor, determine that a display is within a field of view (FOV) of the AR device, determine an eye strain indicator based on the determination that the display is within the FOV of the AR device, and provide the eye strain indicator to the user.

Abstract: Systems and methods are provided for measuring the mechanical properties of ocular tissue, such as the lens or corneal tissue, for diagnosis as well as treatment monitoring purposes. A laser locking feedback system is provided to achieve frequency accuracy and sensitivity that facilitates operations and diagnosis with great sensitivity and accuracy. Differential comparisons between eye tissue regions of a patient, either on the same eye or a fellow eye, can further facilitate early diagnosis and monitoring.

Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

Abstract: A mobile communication device-based corneal topography system includes an illumination system, an imaging system, a topography processor, an image sensor, and a mobile communication device. The illumination system is configured to generate an illumination pattern reflected off a cornea of a subject. The imaging system is coupled to an image sensor to capture an image of the reflected illumination pattern. A topography processor is coupled to the image sensor to process the image of the reflected illumination pattern. The mobile communications device includes a display, the mobile communications device is operatively coupled to the image sensor. The mobile communications device includes a mobile communications device (MCD) processor. A housing at least partially encloses one or more of the illumination system, the imaging system, or the topography processor.

Abstract: Method and contact lens (3) for measuring a subject's three dimensional eye movement including torsional movement. A video camera (1) is provided for recording an image of the subject's eye (2). The contact lens (3) is provided for placement over the subject's eye (2). The contact lens (3) comprises one or more markers (3a,3b) that are detectable by the video camera (1) and are positioned at a lateral offset (D) with respect to a central part (3p) of the contact lens (3). The one or more markers (3a,3b) are configured for detecting torsional rotation (R) of the subject's eye (2) around a line of sight axis (C) of the subject's eye (2) by using the video camera (1) to track a position of the one or more markers (3a,3b).

Abstract: A hand-held sized ocular and neurological screening device, system and method, the screening device comprising an eyepiece and a hand-held housing, the housing comprising a tubular stimulus chamber defining a light stimulus channel, wherein an illumination source is configured to provide light stimulus towards an opening through the light stimulus channel and an operational chamber comprising an infrared camera positioned outside the stimulus channel and inclined towards the opening, the infrared camera is configured to capture images of the pupils and eye movements through the opening without interfering with the light stimulus and a controller configured to receive the captured images from the infrared camera. The hand-held sized device can include a clip-on fixture for fixing the device onto a table, a desktop, or any portable ophthalmic apparatus.

Abstract: A remote interface system according to some embodiments includes one or more patient monitoring devices having one or more sensors for patient monitoring, one or more first processors to receive information from the sensors and generate patient data based thereon, a web server, a first communication system, and a first screen to display a representation of at least a first portion of the patient data, and a remote interface device including a second communication system, a second screen, one or more second processors, an application executed by the one or more second processors and configured to detect a presence of the first communication system, establish a communication link between the first and second communication systems, establish a reliable connection channel (e.g. secure websocket connection) with the web server, receive the patient data via the connection, and display at least a second portion of the patient data on the second screen.

Abstract: The present invention provides for a data acquisition system for EEG and other physiological conditions, preferably wireless, and method of using such system. The wireless EEG system can be used in a number of applications including both studies and clinical work. These include both clinical and research sleep studies, alertness studies, emergency brain monitoring, and any other tests or studies where a subject's or patient's EEG reading is required or helpful. This system includes a number of features, which enhance this system over other systems presently in the marketplace. These features include but are not limited to the having multiple channels for looking at a number of physiological features of the subject or patient, a built in accelerometer for looking at a subject's or patient's body motion, a removable memory for data buffering and storage, capability of operating below 2.

Abstract: The present disclosure relates to systems and methods for scanning a patient in an imaging system. The imaging system may include at least one camera directed at the patient. The systems and methods may obtain a plurality of images of the patient that are captured by the at least one camera. Each of the plurality of images may correspond to one of a series of time points. The systems and methods may also determine a motion of the patient over the series of time points based on the plurality of images of the patient. The systems and methods may further determine whether the patient is ready for scan based on the motion of the patient, and generate control information of the imaging system for scanning the patient in response to determining that the patient is ready for scan.

Abstract: Embodiments herein relate to reflective optical medical sensor devices. In an embodiment, a reflective optical medical sensor device including a central optical detector and a plurality of light emitter units disposed around the central optical detector is provided. A plurality of peripheral optical detectors can be disposed to the outside of the plurality of light emitter units. Each of the plurality of peripheral optical detectors can form a channel pair with one of the plurality of light emitter units. The reflective optical medical sensor device can also include a controller in electrical communication with the central optical detector, the light emitter units, and the peripheral optical detectors. The controller can be configured to measure performance of channel pairs; select a particular channel pair; and measure a physiological parameter using the selected channel pair. Other embodiments are also included herein.

Abstract: The disclosed apparatus, systems and methods relate to devices, systems and methods for intra-operative imaging.

Abstract: A wireless, patient-worn, physiological sensor configured to, among other things, help manage a patient that is at risk of forming one or more pressure ulcers is disclosed. According to an embodiment, the sensor includes a base having a top surface and a bottom surface. The sensor also includes a substrate layer including conductive tracks and connection pads, a top side, and a bottom side, where the bottom side of the substrate layer is disposed above the top side of the base. Mounted on the substrate layer are a processor, a data storage device, a wireless transceiver, an accelerometer, and a battery. In use, the sensor senses a patient's motion and wirelessly transmits information indicative of the sensed motion to, for example, a patient monitor. The patient monitor receives, stores, and processes the transmitted information.

Abstract: A method for estimating blood pressure using a blood flow occlusion system applied to an artery includes receiving from a first sensor a sensed signal; processing at a processor the sensed signal to detect beats in a pulsatile signal; determining validity of the detected beats; storing the detected beats and data associated with the detected beats in the sensed signal as the pressure applied to the artery by the blood flow occlusion system deflates towards a level below a nominal level; determining baseline beat characteristics; evaluating the stored beats and associated data to detect change in beat characteristics as compared to the baseline beat characteristics; selecting a beat before the detected change in the beat characteristic as the last beat indicating the onset of the diastolic blood pressure for the artery; determining a value of the applied pressure at the last beat as the diastolic blood pressure for the artery.

Abstract: An apparatus and method for detecting a bio-signal feature are provided. The apparatus according to one aspect may include: a bio-signal acquirer configured to acquire a bio-signal; and a processor configured to generate an envelope signal of the bio-signal, and detect at least one feature of the bio-signal based on a difference between the envelope signal and the bio-signal.

Abstract: A PPG PRV device for generating a PRV parameter of a PPG signal (20) as an estimation of a HRV parameter of an ECG signal. The PPG PRV device employs a PPG probe (700) and a PPG PRV controller (710). In operation, the PPG probe (700) generate a PPG signal (20). In response thereto, the PPG PRV controller (710) generates a normalized PPG signal (20?) including a plurality of pulses of the PPG signal (20) designated as normal pulses by the PPG PRV controller (710) and excluding at least one pulse of the PPG signal (20) designated at least one abnormal pulse by the PPG PRV controller (710), wherein the normalized PPG signal (20?) is HRV comparable to the ECG signal. The PPG PRV controller (710) derives the PRV parameter from a HRV measurement of the normalized PPG signal (20?).

Abstract: A method for monitoring a health parameter in a person is disclosed. The method involves transmitting radio waves below the skin surface of a person and across a range of stepped frequencies, receiving radio waves on a two-dimensional array of receive antennas, the received radio waves including a reflected portion of the transmitted radio waves across the range of stepped frequencies, generating data that corresponds to the received radio waves, wherein the data includes amplitude and phase data, deriving data from at least one of the amplitude and phase data, and determining a value that is indicative of a health parameter in the person in response to the derived data.

Abstract: An electronic device according to an embodiment includes a speaker capable of outputting a sound wave, a sensor capable of acquiring an optical signal related to blood flow at a measured part of a user, and a controller configured to measure blood flow information of the measured part based on the optical signal. The controller estimates a sleep state of the user based on the blood flow information and controls, based on the sleep state, a sound wave outputted from the speaker.

Abstract: Disclosed are systems, devices, and methods for registering a luminal network to a 3D model of the luminal network. An example method comprises generating a 3D model of a luminal network, identifying a target within the 3D model, determining locations of a plurality of carinas in the luminal network proximate the target, displaying guidance for navigating a location sensor within the luminal network, tracking the location of the location sensor, comparing the tracked locations of the location sensor and the portions of the 3D model representative of open space, displaying guidance for navigating the location sensor a predetermined distance into each lumen originating at the plurality of carinas proximate the target, tracking the location of the location sensor while the location sensor is navigated into each lumen, and updating the registration of the 3D model with the luminal network based on the tracked locations of the location sensor.

Abstract: An apparatus comprising at least two RIP measurement bands further comprises an electric power source arrangement, which excites simultaneously the at least two measurement bands with electric currents of different pseudo random variations, for making respiratory signals output by the at least two measurement bands unique. The apparatus also comprises a wireless transmitter arrangement, which transmits wirelessly respiratory information based on the respiratory signals output by the at least two measurement bands.

Abstract: A spirometry system includes an imaging device configured to capture upper body movement images of a subject during inhalation and exhalation of the subject. The system further includes at least one controller configured to receive the captured images from the imaging device and, based upon the received images, determine at least one of an image-based spirometry flow-volume curve for the subject or an image-based spirometry parameter for the subject.

Abstract: A gas sensor kit includes a gas sensor that measures a gas concentration of an exhalation gas of a subject and a gas supply unit that supplies a therapeutic gas, supplied through a tube, to the subject. In the gas sensor, the gas sensor has a convex portion that is supported when connected with the gas supply unit, and the gas supply unit has at least one locking claw that supports the convex portion when connected with the gas sensor.

Abstract: A method of characterising tremor stability in a subject is described for a subject having an involuntary tremor symptomatic of a neurological disorder. The method comprising: identifying a series of tremor cycles from measured tremor data of the subject, said tremor cycles measuring periodic variation in movement of the subject due to the tremor; determining an instantaneous frequency for each tremor cycle and collating the instantaneous frequencies; determining an instantaneous variation between the instantaneous frequencies of each pair of adjacent tremor cycles within the series; comparing the instantaneous variation to the collation of determined instantaneous frequencies to determine a distribution of instantaneous variations; and determining an index value of the distribution of the instantaneous variations, said index value defining the stability of the tremor.

Abstract: Generally, methods, devices, and systems related to analyte monitoring and data logging are provided—e.g., as related to in vivo analyte monitoring devices and systems. In some aspects, methods, devices, and systems are provided that relate to enable related settings based on an expected use of an in vivo positioned sensor; logging or otherwise recording analyte levels acquired or derived—e.g., sample analyte levels more frequently than they are logged or otherwise recorded in memory; dynamically adjust the data logging frequency; randomly determine times of acquiring or storing analyte levels from the in-vivo positioned analyte sensors; and enable recording related settings when the system is operable.

Abstract: An apparatus including a controller can determine a rate of change of a blood glucose level of a subject from blood glucose data and determine if there is a risk of the blood glucose level going high or low.

Abstract: Briefly, a sensor for a continuous biological monitor is provided for measuring the level of a target analyte for a patient. The sensor has a working wire and a reference wire, where the working wire has an analyte limiting layer that passes more than 1 in 1000 analyte molecules from the patient to the an enzyme layer. The enzyme layer has an enzyme entrapped in a polyurethane cross-linked with acrylic polyol. As free electrons are generated, a conductor transfers the electrons to the biological monitor. In some cases, the sensor may be constructed without the use of any expensive platinum.

Abstract: A hand-held applicator (10) for collecting, mixing, diluting and discharging a sample liquid, comprising a main body (20) having an inlet-aperture (24), an outlet-aperture (26) and a chamber (22) for storing a liquid solution, wherein the chamber is connected to the inlet-aperture and the outlet-aperture, a lid (12) for covering the inlet-aperture and a tube (40), moveably supported in the inlet-aperture when the lid is covering the upper portion of the main body, wherein the tube (40) is moveable between a predetermined position outside the chamber and a position, in which the tube is at least partly located in the chamber.

Abstract: A sleepiness estimating device including an auxiliary information acquirer that acquires auxiliary information including at least one of five-sense information perceived by a person or emotion information indicating an emotion of the person; and a sleepiness estimator that estimates a sleepiness of the person based on the auxiliary information.

Abstract: Embodiments of the invention provide devices and systems to monitor fullness of a patient's bladder. One embodiment of a bladder fullness (BF) measure system comprises a sensor device (SD) and a controller. The SD generates an output signal (OS) based on the force exerted by the bladder against SD the wherein the OS corresponds to a degree of BF. The SD may be attached to the bladder wall or adjoining tissue and positioned between the bladder and the pubic bone such that the SD is not affected by tissues force other than that from the bladder. The controller connects to the SD and causes an associated implant to perform a function when the SD output signal exceeds a predetermined threshold. Embodiments are particularly useful for providing information on BF to patients suffering from spinal injury or other conditions whereby they have lost the ability to sense BF and/or voluntarily urinate.

Abstract: A stimulation device includes an adapter component to increase the usability of the stimulation device. The adapter may be a bipolar adapter arranged to connect to the housing of the stimulation device. The adapter may include a clip having a first channel configured to receive an operative element therein and a second channel having a return operative element therein. The return operative element is in electrical communication with an electrical circuit of said stimulation control device. Alternatively, the adapter may be a percutaneous adapter comprising a connector configured to connect to an operative element of a stimulation device and a lead wire connected to the connector. A needle may be connected to the lead wire to deliver a electrical stimulation signal to a target tissue located beneath the skin of a subject patient.

Abstract: The electronic device includes a pad module and a main module. At least part of the patch module is attached to a user to obtain a bio-signal of the user. The pad module includes a first housing and a plurality of first electrodes disposed in the first housing. The main module is configured to record the bio-signal of the user that is transferred through the pad module. The main module includes a second housing that is coupled with the first housing in a first direction. The main module also includes a plurality of second electrodes disposed in the second housing. The plurality of second electrodes are configured to make electrical contact with the plurality of first electrodes. The main module further includes a plurality of magnetic bodies disposed in the second housing to correspond to positions of the plurality of second electrodes.

Abstract: Methods, systems, and computer programs encoded on a computer storage medium, for improving EEG measurements by identifying artifacts present in EEG measurements and providing a real-time indication to a user of likely artifacts in EEG measurements are described. EEG measurements of a patient can be obtained by placing a wearable device or EEG cap on a patient's head. Sensors in the cap provide EEG data to a computing device that processes the data to identify one or more artifacts in the EEG data. The artifacts can be identified by conducting one or more operations of determining the signal to noise ratio of the line noise, calculating mutual information between sensor pairs, and applying the p-welch method. Based on the types of artifacts identified, the computing device can output an indicator that provides feedback to the technician performing an EEG test to make adjustments to the test setup.

Abstract: An electrocardiogram analysis apparatus includes: an electrocardiogram signal inputting section to which electrocardiogram signals of measurement electrodes attached to a subject are input; a mistaken attachment determining section which, by using the input electrocardiogram signals, determines whether the measurement electrodes are mistakenly attached or not; an outputting section which, if it is determined that the measurement electrodes are mistakenly attached, notifies of mistaken attachment of the measurement electrodes; and an electrocardiogram data storing section which, in a case where there is an input indicative of confirmation of the notification, stores information indicating that the measurement electrodes have been checked, together with the input electrocardiogram signals, and, in a case where there is not an input indicative of confirmation of the notification, stores information indicating that the measurement electrodes have not been checked, together with the input electrocardiogram signals

Abstract: An apparatus includes data acquisition circuitry and a processor. The data acquisition circuitry is configured to acquire multiple signals using multiple respective electrodes of an array of electrodes coupled to one of an organ of a patient and tissue or a cell culture. The processor is configured to hold a definition of a mixed-norm that is defined as a function of relative positions of the electrodes in the array, and jointly compress the multiple signals in a compressed-sensing (CS) process that minimizes the mixed-norm.

Abstract: Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.

Abstract: A medical device is utilized to monitor physiological parameters of a patient and capture segments of the monitored physiological parameters. The medical device includes circuitry configured to monitor one or more physiological parameters associated with the patient and an analysis module that includes a buffer and a processor. The buffer stores monitored physiological parameters and the processor analyzes the monitored physiological parameters and triggers capture of segments from the buffer in response to a triggering criteria being satisfied. The analysis module selects a pre-trigger duration based at least in part on the triggering criteria.

Abstract: An example device for detecting one or more parameters of a cardiac signal is disclosed herein. The device includes one or more electrodes and sensing circuitry configured to sense a cardiac signal via the one or more electrodes. The device further includes processing circuitry configured to determine an R-wave of the cardiac signal and determine whether the R-wave is noisy. Based on the R-wave being noisy, the processing circuitry is configured to determine whether the cardiac signal around a determined T-wave is noisy. Based on the cardiac signal around the determined T-wave not being noisy, the processing circuitry is configured to determine a QT interval or a corrected QT interval based on the determined T-wave and the determined R-wave.

Abstract: A medical device is configured to detect an atrial tachyarrhythmia episode. The device senses a cardiac signal, identifies R-waves in the cardiac signal attendant ventricular depolarizations and determines classification factors from the R-waves identified over a predetermined time period. The device classifies the predetermined time period as one of unclassified, atrial tachyarrhythmia and non-atrial tachyarrhythmia by comparing the determined classification factors to classification criteria. A classification criterion is adjusted from a first classification criterion to a second classification criterion after at least one time period being classified as atrial tachyarrhythmia. An atrial tachyarrhythmia episode is detected by the device in response to at least one subsequent time period being classified as atrial tachyarrhythmia based on the adjusted classification criterion.

Abstract: This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.

Abstract: The present disclosure relates to noninvasive methods for detecting liver fibrosis. Disclosed herein are noninvasive liver fibrosis detection methods that use Doppler Ultrasound devices and a physics-based machine learning method. Further disclosed herein are methods for detecting liver fibrosis in a subject by detecting and measuring the presence of a shift in the frequency of blood flow in the hepatic vein as compared to the frequency of blood flow in the portal vein.

Abstract: The various embodiments of the method of the present invention include a method to improving or expanding the capacity of a sleep analysis unit or laboratory, a method sleep analysis testing a patient admitted for diagnosis or treatment of another primary medical condition while being treated or diagnosed for that condition, a method of sleep analysis testing a patient that cannot be easily moved or treated in a sleep analysis unit or laboratory and other like methods.

Abstract: A wearable device includes a wearable device main body, a sensor part configured to contact a skin surface of a user of the wearable device, and measure a bio-signal of the user, and a shock absorber that is interposed between the wearable device main body and the sensor part to mechanically connect the wearable device main body and the sensor part, and that is configured to reduce motion transmission between the wearable device main body and the sensor part to permit the wearable device main body to move independently from the sensor part.

Abstract: A sensor apparatus includes at least one substrate layer of an elastically deformable material, the substrate layer extending longitudinally between spaced apart ends thereof. A conductive layer is attached to and extends longitudinally between the spaced apart ends of the at least one substrate layer. The conductive layer includes an electrically conductive material adapted to form a strain gauge having an electrical resistance that varies based on deformation of the conductive layer in at least one direction.